CN112888481A - 包含tnfr2结构域的新型car构建体 - Google Patents

包含tnfr2结构域的新型car构建体 Download PDF

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CN112888481A
CN112888481A CN201980066796.1A CN201980066796A CN112888481A CN 112888481 A CN112888481 A CN 112888481A CN 201980066796 A CN201980066796 A CN 201980066796A CN 112888481 A CN112888481 A CN 112888481A
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seq
cells
car
fragment
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T·亚伯
达维德·弗纳尔
J·格特纳-达登内
F·迈耶
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Sangamo Biotherapy France
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CN201980066796.1A 2018-08-10 2019-08-09 包含tnfr2结构域的新型car构建体 Pending CN112888481A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862717234P 2018-08-10 2018-08-10
US62/717,234 2018-08-10
PCT/IB2019/000907 WO2020030979A2 (en) 2018-08-10 2019-08-09 New car constructs comprising tnfr2 domains

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CN112888481A true CN112888481A (zh) 2021-06-01

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CN201980066796.1A Pending CN112888481A (zh) 2018-08-10 2019-08-09 包含tnfr2结构域的新型car构建体

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US (1) US20210292389A1 (https=)
EP (1) EP3833446A2 (https=)
JP (2) JP2021534815A (https=)
KR (1) KR20210046006A (https=)
CN (1) CN112888481A (https=)
AU (1) AU2019318135A1 (https=)
BR (1) BR112021002579A2 (https=)
CA (1) CA3109253A1 (https=)
IL (1) IL280697A (https=)
MX (1) MX2021001592A (https=)
SG (1) SG11202101415UA (https=)
WO (1) WO2020030979A2 (https=)

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WO2021183795A1 (en) * 2020-03-11 2021-09-16 Poseida Therapeutics, Inc. Chimeric stimulatory receptors and methods of use in t cell activation and differentiation
CN113528449A (zh) * 2020-04-20 2021-10-22 浙江瑞加美生物科技有限公司 一种制备通用型人源化car19-dnt细胞的技术及其应用
KR102937100B1 (ko) * 2021-01-20 2026-03-12 서울대학교산학협력단 항-c4d 키메라 항원 수용체 조절 t 세포 및 이의 용도
KR20240025524A (ko) * 2021-06-25 2024-02-27 상가모 테라퓨틱스, 인코포레이티드 Il-23r에 특이적인 항원 결합제 및 이의 용도
CA3226798A1 (en) * 2021-07-29 2023-02-02 James MATTHAEI Synovial extracellular matrix-specific chimeric antigen receptor for targeting regulatory t cells to treat autoimmune diseases
WO2023076912A2 (en) * 2021-10-26 2023-05-04 ImmPACT Bio USA Inc. Cd4+ and/or cd8+ cell populations comprising icars for use in treatment therapies
US20250099584A1 (en) * 2022-02-18 2025-03-27 Institut National de la Santé et de la Recherche Médicale Use of tcr-deficient car-tregs in combination with anti-tcr complex monoclonal antibodies for inducing durable tolerance
WO2025006795A1 (en) * 2023-06-30 2025-01-02 Board Of Regents, The University Of Texas System Tsyn-seq: a t cell synapse-based tumor antigen identification platform
WO2025170881A1 (en) * 2024-02-06 2025-08-14 The Board Of Trustees Of The University Of Illinois Methods and kits for reducing the risk of allograft rejection
WO2025250847A1 (en) * 2024-05-29 2025-12-04 The Texas A&M University System Compositions containing hsp60-specific regulatory t cells and methods of treatment using the same

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