CN112868086A - 使与质谱系统一起应用的取样元件官能化的方法 - Google Patents

使与质谱系统一起应用的取样元件官能化的方法 Download PDF

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Publication number
CN112868086A
CN112868086A CN201980068358.9A CN201980068358A CN112868086A CN 112868086 A CN112868086 A CN 112868086A CN 201980068358 A CN201980068358 A CN 201980068358A CN 112868086 A CN112868086 A CN 112868086A
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China
Prior art keywords
silicate
sampling element
antibody
elongated
analyte
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Pending
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CN201980068358.9A
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English (en)
Chinese (zh)
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T·R·科维
刘畅
S·普尔卡亚沙
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DH Technologies Development Pte Ltd
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DH Technologies Development Pte Ltd
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Publication of CN112868086A publication Critical patent/CN112868086A/zh
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    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/02Details
    • H01J49/04Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN201980068358.9A 2018-10-18 2019-10-17 使与质谱系统一起应用的取样元件官能化的方法 Pending CN112868086A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862747480P 2018-10-18 2018-10-18
US62/747,480 2018-10-18
PCT/IB2019/058876 WO2020079647A1 (en) 2018-10-18 2019-10-17 Functionalizing a sampling element for use with a mass spectrometry system

Publications (1)

Publication Number Publication Date
CN112868086A true CN112868086A (zh) 2021-05-28

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CN201980068358.9A Pending CN112868086A (zh) 2018-10-18 2019-10-17 使与质谱系统一起应用的取样元件官能化的方法

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Country Link
EP (1) EP3867943A1 (de)
JP (1) JP2022505162A (de)
CN (1) CN112868086A (de)
WO (1) WO2020079647A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4154013A1 (de) * 2020-05-22 2023-03-29 DH Technologies Development Pte. Ltd. Festphasenaffinitätsauswahl durch massenspektrometrie
CN116615649A (zh) * 2020-12-22 2023-08-18 豪夫迈·罗氏有限公司 自动化临床诊断系统和方法
JP2024507179A (ja) * 2021-02-25 2024-02-16 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド サンプリングのためのシステムおよび方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1010008A2 (de) * 1997-09-02 2000-06-21 Sequenom, Inc. Massenspektrometrischer nachweis von polypeptiden
CN1360732A (zh) * 1999-04-27 2002-07-24 赛弗根生物系统股份有限公司 气相离子谱仪的探头
WO2015188282A1 (en) * 2014-06-13 2015-12-17 Pawliszyn Janusz B A probe for extraction of molecules of interest from a sample
US20170316926A1 (en) * 2016-04-29 2017-11-02 DH Technologies Development Pte Ltd. Sampling Interface for Mass Spectrometry Systems and Methods
WO2018069872A1 (en) * 2016-10-14 2018-04-19 Dh Technologies Development Pte. Ltd. Methods and systems for increasing sensitivity of direct sampling interfaces for mass spectrometric analysis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US20090026122A1 (en) * 2002-03-11 2009-01-29 Janusz Biocompatible solid-phase microextraction coatings and methods for their preparation

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1010008A2 (de) * 1997-09-02 2000-06-21 Sequenom, Inc. Massenspektrometrischer nachweis von polypeptiden
CN1360732A (zh) * 1999-04-27 2002-07-24 赛弗根生物系统股份有限公司 气相离子谱仪的探头
WO2015188282A1 (en) * 2014-06-13 2015-12-17 Pawliszyn Janusz B A probe for extraction of molecules of interest from a sample
US20170316926A1 (en) * 2016-04-29 2017-11-02 DH Technologies Development Pte Ltd. Sampling Interface for Mass Spectrometry Systems and Methods
WO2018069872A1 (en) * 2016-10-14 2018-04-19 Dh Technologies Development Pte. Ltd. Methods and systems for increasing sensitivity of direct sampling interfaces for mass spectrometric analysis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MUKESH DIGAMBAR SONAWANE: "surface modification chemistries of materials used in diagnostic platforms with biomolecules", JOURNAL OF CHEMISTRY, pages 1 - 20 *

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EP3867943A1 (de) 2021-08-25
WO2020079647A1 (en) 2020-04-23
JP2022505162A (ja) 2022-01-14

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