CN112805269A - 用于制备烷氧基亚甲基-苯甲酰基乙腈的合成方法 - Google Patents
用于制备烷氧基亚甲基-苯甲酰基乙腈的合成方法 Download PDFInfo
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- CN112805269A CN112805269A CN201980063103.3A CN201980063103A CN112805269A CN 112805269 A CN112805269 A CN 112805269A CN 201980063103 A CN201980063103 A CN 201980063103A CN 112805269 A CN112805269 A CN 112805269A
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- orthoformate
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Images
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D3/00—Distillation or related exchange processes in which liquids are contacted with gaseous media, e.g. stripping
- B01D3/009—Distillation or related exchange processes in which liquids are contacted with gaseous media, e.g. stripping in combination with chemical reactions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D3/00—Distillation or related exchange processes in which liquids are contacted with gaseous media, e.g. stripping
- B01D3/10—Vacuum distillation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/32—Separation; Purification; Stabilisation; Use of additives
- C07C253/34—Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/54—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1815699.2A GB201815699D0 (en) | 2018-09-26 | 2018-09-26 | Synthetic method |
| GB1815699.2 | 2018-09-26 | ||
| PCT/GB2019/052720 WO2020065325A1 (en) | 2018-09-26 | 2019-09-26 | Synthetic methodfor the preparation of an alkoxymethylene-benzoylacetonitrile |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN112805269A true CN112805269A (zh) | 2021-05-14 |
Family
ID=64024259
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201980063103.3A Pending CN112805269A (zh) | 2018-09-26 | 2019-09-26 | 用于制备烷氧基亚甲基-苯甲酰基乙腈的合成方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20220033352A1 (https=) |
| EP (1) | EP3856712B1 (https=) |
| JP (1) | JP2022502413A (https=) |
| KR (1) | KR20210065110A (https=) |
| CN (1) | CN112805269A (https=) |
| AU (1) | AU2019348974A1 (https=) |
| CA (1) | CA3113000A1 (https=) |
| DK (1) | DK3856712T3 (https=) |
| ES (1) | ES2933687T3 (https=) |
| GB (1) | GB201815699D0 (https=) |
| IL (1) | IL281635A (https=) |
| WO (1) | WO2020065325A1 (https=) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3658838A (en) * | 1968-11-16 | 1972-04-25 | Bayer Ag | Process for the preparation of 1 5-disubstituted-4-cyano-pyrazoles |
| US4686221A (en) * | 1985-10-01 | 1987-08-11 | Kanebo, Ltd. | Quinolinecarboxylic acid compounds and antimicrobial agent containing the same |
| CN1832928A (zh) * | 2003-06-26 | 2006-09-13 | 诺瓦提斯公司 | 以5元杂环为基础的p38激酶抑制剂 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62174055A (ja) * | 1985-10-01 | 1987-07-30 | Kanebo Ltd | 新規キノリンカルボン酸誘導体および該化合物を有効成分とする抗菌剤 |
| CA2329065A1 (en) * | 1998-05-05 | 1999-11-11 | Francisco Xavier Talamas | Pyrazole derivatives as p-38 map kinase inhibitors |
-
2018
- 2018-09-26 GB GBGB1815699.2A patent/GB201815699D0/en not_active Ceased
-
2019
- 2019-09-26 EP EP19780307.5A patent/EP3856712B1/en active Active
- 2019-09-26 ES ES19780307T patent/ES2933687T3/es active Active
- 2019-09-26 JP JP2021516981A patent/JP2022502413A/ja not_active Ceased
- 2019-09-26 CA CA3113000A patent/CA3113000A1/en active Pending
- 2019-09-26 WO PCT/GB2019/052720 patent/WO2020065325A1/en not_active Ceased
- 2019-09-26 CN CN201980063103.3A patent/CN112805269A/zh active Pending
- 2019-09-26 DK DK19780307.5T patent/DK3856712T3/da active
- 2019-09-26 AU AU2019348974A patent/AU2019348974A1/en not_active Abandoned
- 2019-09-26 KR KR1020217008900A patent/KR20210065110A/ko not_active Ceased
- 2019-09-26 US US17/279,326 patent/US20220033352A1/en not_active Abandoned
-
2021
- 2021-03-18 IL IL281635A patent/IL281635A/en unknown
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3658838A (en) * | 1968-11-16 | 1972-04-25 | Bayer Ag | Process for the preparation of 1 5-disubstituted-4-cyano-pyrazoles |
| US4686221A (en) * | 1985-10-01 | 1987-08-11 | Kanebo, Ltd. | Quinolinecarboxylic acid compounds and antimicrobial agent containing the same |
| CN1832928A (zh) * | 2003-06-26 | 2006-09-13 | 诺瓦提斯公司 | 以5元杂环为基础的p38激酶抑制剂 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2020065325A1 (en) | 2020-04-02 |
| DK3856712T3 (da) | 2022-12-12 |
| CA3113000A1 (en) | 2020-04-02 |
| IL281635A (en) | 2021-05-31 |
| KR20210065110A (ko) | 2021-06-03 |
| AU2019348974A1 (en) | 2021-04-22 |
| EP3856712B1 (en) | 2022-10-26 |
| ES2933687T3 (es) | 2023-02-13 |
| JP2022502413A (ja) | 2022-01-11 |
| GB201815699D0 (en) | 2018-11-07 |
| US20220033352A1 (en) | 2022-02-03 |
| EP3856712A1 (en) | 2021-08-04 |
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