GB201815699D0 - Synthetic method - Google Patents

Synthetic method

Info

Publication number
GB201815699D0
GB201815699D0 GBGB1815699.2A GB201815699A GB201815699D0 GB 201815699 D0 GB201815699 D0 GB 201815699D0 GB 201815699 A GB201815699 A GB 201815699A GB 201815699 D0 GB201815699 D0 GB 201815699D0
Authority
GB
United Kingdom
Prior art keywords
synthetic method
synthetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1815699.2A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mereo Biopharma 1 Ltd
Original Assignee
Mereo Biopharma 1 Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mereo Biopharma 1 Ltd filed Critical Mereo Biopharma 1 Ltd
Priority to GBGB1815699.2A priority Critical patent/GB201815699D0/en
Publication of GB201815699D0 publication Critical patent/GB201815699D0/en
Priority to ES19780307T priority patent/ES2933687T3/es
Priority to US17/279,326 priority patent/US20220033352A1/en
Priority to CA3113000A priority patent/CA3113000A1/en
Priority to EP19780307.5A priority patent/EP3856712B1/en
Priority to DK19780307.5T priority patent/DK3856712T3/da
Priority to KR1020217008900A priority patent/KR20210065110A/ko
Priority to JP2021516981A priority patent/JP2022502413A/ja
Priority to PCT/GB2019/052720 priority patent/WO2020065325A1/en
Priority to CN201980063103.3A priority patent/CN112805269A/zh
Priority to AU2019348974A priority patent/AU2019348974A1/en
Priority to IL281635A priority patent/IL281635A/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D3/00—Distillation or related exchange processes in which liquids are contacted with gaseous media, e.g. stripping
    • B01D3/009—Distillation or related exchange processes in which liquids are contacted with gaseous media, e.g. stripping in combination with chemical reactions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D3/00—Distillation or related exchange processes in which liquids are contacted with gaseous media, e.g. stripping
    • B01D3/10—Vacuum distillation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/32—Separation; Purification; Stabilisation; Use of additives
    • C07C253/34—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/54—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GBGB1815699.2A 2018-09-26 2018-09-26 Synthetic method Ceased GB201815699D0 (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
GBGB1815699.2A GB201815699D0 (en) 2018-09-26 2018-09-26 Synthetic method
AU2019348974A AU2019348974A1 (en) 2018-09-26 2019-09-26 Synthetic methodfor the preparation of an alkoxymethylene-benzoylacetonitrile
EP19780307.5A EP3856712B1 (en) 2018-09-26 2019-09-26 Synthetic methodfor the preparation of an alkoxymethylene-benzoylacetonitrile
US17/279,326 US20220033352A1 (en) 2018-09-26 2019-09-26 Synthetic method for the preparation of an alkoxymethylene-benzoylacetonitrile
CA3113000A CA3113000A1 (en) 2018-09-26 2019-09-26 Synthetic method for the preparation of an alkoxymethylene-benzoylacetonitrile
ES19780307T ES2933687T3 (es) 2018-09-26 2019-09-26 Método de síntesis para la preparación de un alcoximetilen-benzoilacetonitrilo
DK19780307.5T DK3856712T3 (da) 2018-09-26 2019-09-26 Syntetisk fremgangsmåde til fremstillingen af en alkoxymethylen-benzoylacetonitril
KR1020217008900A KR20210065110A (ko) 2018-09-26 2019-09-26 알콕시메틸렌-벤조일아세토니트릴의 제조를 위한 합성 방법
JP2021516981A JP2022502413A (ja) 2018-09-26 2019-09-26 アルコキシメチレン−ベンゾイルアセトニトリルの調製のための合成方法
PCT/GB2019/052720 WO2020065325A1 (en) 2018-09-26 2019-09-26 Synthetic methodfor the preparation of an alkoxymethylene-benzoylacetonitrile
CN201980063103.3A CN112805269A (zh) 2018-09-26 2019-09-26 用于制备烷氧基亚甲基-苯甲酰基乙腈的合成方法
IL281635A IL281635A (en) 2018-09-26 2021-03-18 A synthetic method for the preparation of Alkoxymethylene-Benzoyllactonitrile

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1815699.2A GB201815699D0 (en) 2018-09-26 2018-09-26 Synthetic method

Publications (1)

Publication Number Publication Date
GB201815699D0 true GB201815699D0 (en) 2018-11-07

Family

ID=64024259

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1815699.2A Ceased GB201815699D0 (en) 2018-09-26 2018-09-26 Synthetic method

Country Status (12)

Country Link
US (1) US20220033352A1 (https=)
EP (1) EP3856712B1 (https=)
JP (1) JP2022502413A (https=)
KR (1) KR20210065110A (https=)
CN (1) CN112805269A (https=)
AU (1) AU2019348974A1 (https=)
CA (1) CA3113000A1 (https=)
DK (1) DK3856712T3 (https=)
ES (1) ES2933687T3 (https=)
GB (1) GB201815699D0 (https=)
IL (1) IL281635A (https=)
WO (1) WO2020065325A1 (https=)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1809386A1 (de) * 1968-11-16 1970-06-11 Bayer Ag Verfahren zur Herstellung von 1,5-disubstituierten 4-Cyanopyrazolen
JPS62174055A (ja) * 1985-10-01 1987-07-30 Kanebo Ltd 新規キノリンカルボン酸誘導体および該化合物を有効成分とする抗菌剤
US4686221A (en) * 1985-10-01 1987-08-11 Kanebo, Ltd. Quinolinecarboxylic acid compounds and antimicrobial agent containing the same
CA2329065A1 (en) * 1998-05-05 1999-11-11 Francisco Xavier Talamas Pyrazole derivatives as p-38 map kinase inhibitors
KR101120857B1 (ko) 2003-06-26 2012-04-12 노파르티스 아게 5원의 헤테로사이클-기재 ｐ38 키나제 억제제

Also Published As

Publication number Publication date
WO2020065325A1 (en) 2020-04-02
CN112805269A (zh) 2021-05-14
DK3856712T3 (da) 2022-12-12
CA3113000A1 (en) 2020-04-02
IL281635A (en) 2021-05-31
KR20210065110A (ko) 2021-06-03
AU2019348974A1 (en) 2021-04-22
EP3856712B1 (en) 2022-10-26
ES2933687T3 (es) 2023-02-13
JP2022502413A (ja) 2022-01-11
US20220033352A1 (en) 2022-02-03
EP3856712A1 (en) 2021-08-04

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)