CN112805015A - 造血干细胞和造血祖细胞扩增系统 - Google Patents

造血干细胞和造血祖细胞扩增系统 Download PDF

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CN112805015A
CN112805015A CN201980065957.5A CN201980065957A CN112805015A CN 112805015 A CN112805015 A CN 112805015A CN 201980065957 A CN201980065957 A CN 201980065957A CN 112805015 A CN112805015 A CN 112805015A
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inhibitor
medium
acid
growth medium
supplement
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Chinese (zh)
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J·塞
A·贝克尔
N·考尔
M·维穆里
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Life Technologies Corp
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Life Technologies Corp
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/22—Colony stimulating factors (G-CSF, GM-CSF)
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
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    • C12N2501/20—Cytokines; Chemokines
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    • C12N2501/20—Cytokines; Chemokines
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2510/00—Genetically modified cells

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  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
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  • Wood Science & Technology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN201980065957.5A 2018-10-12 2019-10-14 造血干细胞和造血祖细胞扩增系统 Pending CN112805015A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862745208P 2018-10-12 2018-10-12
US62/745,208 2018-10-12
US201962854250P 2019-05-29 2019-05-29
US62/854,250 2019-05-29
PCT/US2019/056145 WO2020077343A1 (en) 2018-10-12 2019-10-14 Hematopoietic stem and progenitor cell expansion system

Publications (1)

Publication Number Publication Date
CN112805015A true CN112805015A (zh) 2021-05-14

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US (1) US20210386787A1 (https=)
EP (1) EP3863648A1 (https=)
JP (2) JP2022504722A (https=)
KR (1) KR20210076048A (https=)
CN (1) CN112805015A (https=)
WO (1) WO2020077343A1 (https=)

Cited By (2)

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CN114891749A (zh) * 2022-07-13 2022-08-12 杭州艾名医学科技有限公司 一种胰腺癌类器官的培养基及胰腺癌类器官的培养方法
CN115644066A (zh) * 2022-12-02 2023-01-31 福建农林大学 利用外源多胺提高龙眼胚性愈伤组织生长量和类黄酮含量的方法

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JP2024539519A (ja) * 2021-10-20 2024-10-28 エクシール， インク． 非ヒト霊長類の個別化されたゲノムアセンブリ及び人工多能性幹細胞株を前臨床評価に使用するための組成物及び方法
CN115975929A (zh) * 2022-08-18 2023-04-18 南通大学 Kat2a抑制剂在治疗脊髓及坐骨神经损伤中的应用
LU507930B1 (en) * 2024-08-05 2026-02-05 Luxembourg Institute Of Science And Tech Serum-free culture medium for the culture of human monocytic cells and method using the same

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US20040087652A1 (en) * 2000-07-07 2004-05-06 Goettlicher Martin Valproic acid and derivatives thereof as histone deacetylase inhibitors
US20090253203A1 (en) * 2005-08-01 2009-10-08 Nupotential, Inc. Reprogramming a Cell by Inducing a Pluripotent Gene Through Use of a Small Molecule Modulator
WO2011158806A1 (ja) * 2010-06-14 2011-12-22 日産化学工業株式会社 造血幹細胞の製造方法
CN102307990A (zh) * 2008-12-03 2012-01-04 国际干细胞公司 从干细胞衍生分化细胞的方法
US20120207744A1 (en) * 2009-03-19 2012-08-16 Mendlein John D Reprogramming compositions and methods of using the same
US20130171110A1 (en) * 2011-12-05 2013-07-04 DeWitt Ross & Stevens S.C. Compositions and methods for differentiating pluripotent stem cells into primitive blood cells and uses thereof
WO2016020434A1 (en) * 2014-08-06 2016-02-11 Johann Wolfgang Goethe-Universität Method for expanding immune cells
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US20180187156A1 (en) * 2015-06-25 2018-07-05 Children's Medical Center Corporation Methods and compositions relating to hematopoietic stem cell expansion, enrichment, and maintenance
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JP2009509911A (ja) * 2005-05-05 2009-03-12 リージェンツ オブ ザ ユニバーシティ オブ ミネソタ リンパ造血組織を定着させるためのｍａｐｃまたはそれらの子孫の使用
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US20090253203A1 (en) * 2005-08-01 2009-10-08 Nupotential, Inc. Reprogramming a Cell by Inducing a Pluripotent Gene Through Use of a Small Molecule Modulator
CN102307990A (zh) * 2008-12-03 2012-01-04 国际干细胞公司 从干细胞衍生分化细胞的方法
US20120207744A1 (en) * 2009-03-19 2012-08-16 Mendlein John D Reprogramming compositions and methods of using the same
WO2011158806A1 (ja) * 2010-06-14 2011-12-22 日産化学工業株式会社 造血幹細胞の製造方法
US20130171110A1 (en) * 2011-12-05 2013-07-04 DeWitt Ross & Stevens S.C. Compositions and methods for differentiating pluripotent stem cells into primitive blood cells and uses thereof
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US20180187156A1 (en) * 2015-06-25 2018-07-05 Children's Medical Center Corporation Methods and compositions relating to hematopoietic stem cell expansion, enrichment, and maintenance
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114891749A (zh) * 2022-07-13 2022-08-12 杭州艾名医学科技有限公司 一种胰腺癌类器官的培养基及胰腺癌类器官的培养方法
CN115644066A (zh) * 2022-12-02 2023-01-31 福建农林大学 利用外源多胺提高龙眼胚性愈伤组织生长量和类黄酮含量的方法
CN115644066B (zh) * 2022-12-02 2024-01-16 福建农林大学 利用外源多胺提高龙眼胚性愈伤组织生长量和类黄酮含量的方法

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Publication number Publication date
KR20210076048A (ko) 2021-06-23
EP3863648A1 (en) 2021-08-18
JP2024137954A (ja) 2024-10-07
JP2022504722A (ja) 2022-01-13
US20210386787A1 (en) 2021-12-16
WO2020077343A1 (en) 2020-04-16

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