CN112804993A - 氯法齐明的组合物,含它们的组合,它们的制备方法,含它们的用途和方法 - Google Patents
氯法齐明的组合物,含它们的组合,它们的制备方法,含它们的用途和方法 Download PDFInfo
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- CN112804993A CN112804993A CN201980064766.7A CN201980064766A CN112804993A CN 112804993 A CN112804993 A CN 112804993A CN 201980064766 A CN201980064766 A CN 201980064766A CN 112804993 A CN112804993 A CN 112804993A
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- clofazimine
- pharmaceutical composition
- infection
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- mycobacterium
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- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
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- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
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Landscapes
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- Inorganic Chemistry (AREA)
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Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862722048P | 2018-08-23 | 2018-08-23 | |
US62/722,048 | 2018-08-23 | ||
US201962796822P | 2019-01-25 | 2019-01-25 | |
US62/796,822 | 2019-01-25 | ||
PCT/US2019/025538 WO2020040818A1 (en) | 2018-08-23 | 2019-04-03 | Compositions of clofazimine, combinations comprising them, processes for their preparation, uses and methods comprising them |
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JP (2) | JP7377259B2 (ja) |
KR (1) | KR20210090607A (ja) |
CN (1) | CN112804993A (ja) |
AU (1) | AU2019324330A1 (ja) |
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CN114507189A (zh) * | 2021-12-08 | 2022-05-17 | 余述南 | 一种化学合成的原料药及其治疗结核病及耐药性结核病的用途 |
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CN114828828A (zh) * | 2019-11-06 | 2022-07-29 | 曼金德公司 | 氯法齐明的组合物,含它们的组合,它们的制备方法,含它们的用途和治疗方法 |
CN111634940B (zh) * | 2020-05-27 | 2021-10-29 | 中国地质大学(武汉) | 一种单质金均匀负载钛酸盐纳米材料的制备方法 |
CN112521339A (zh) * | 2020-11-20 | 2021-03-19 | 山西立业制药有限公司 | 一种氯苯吩嗪的制备方法 |
US11793808B2 (en) * | 2021-02-22 | 2023-10-24 | Mannkind Corp. | Compositions of clofazimine, combinations comprising them, processes for their preparation, uses and methods comprising them |
CN115737560A (zh) * | 2022-12-27 | 2023-03-07 | 四川农业大学 | 一种酸响应的一氧化氮/活性氧纳米发生器及其制备方法 |
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CN114507189A (zh) * | 2021-12-08 | 2022-05-17 | 余述南 | 一种化学合成的原料药及其治疗结核病及耐药性结核病的用途 |
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CA3109572A1 (en) | 2020-02-27 |
KR20210090607A (ko) | 2021-07-20 |
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