CN112718031A

CN112718031A - Biochemical test paper tube

Info

Publication number: CN112718031A
Application number: CN202110098826.6A
Authority: CN
Inventors: 钱锐泽; 韦里; 周中人
Original assignee: Shanghai Miaoling Bioengineering Co ltd; Shanghai Quicking Biotech Co ltd
Current assignee: Shanghai Miaoling Bioengineering Co ltd; Shanghai Quicking Biotech Co ltd
Priority date: 2020-06-19
Filing date: 2021-01-25
Publication date: 2021-04-30
Anticipated expiration: 2041-01-25
Also published as: CN214553632U; CN112718031B

Abstract

The invention relates to a biochemical test paper tube, which comprises a tube part and a cover part; the pipe portion includes: a solution chamber; the test paper fixing part is horizontally spaced from the outer edge of the test paper fixing part and the inner wall of the pipe part; wherein, under the condition that the cap part seals the tube part, the top of the solution cavity is communicated with the top of the test paper fixing part, and a horizontal interval is arranged between the outer edge of the test paper fixing part and the inner wall of the cap part. The biochemical test paper fixing part has the advantages that the horizontal interval is formed between the test paper fixing part and the inner wall of the pipe part, and the biochemical test paper is prevented from contacting with the inner wall of the pipe part or forming an adherence to the wall to influence the detection effect under the condition that the biochemical test paper is placed on the test paper fixing part.

Description

Biochemical test paper tube

Technical Field

The invention relates to the technical field of rapid detection devices, in particular to a biochemical test paper tube.

Background

In vitro diagnosis or in vitro detection, a combination of a chromatography test paper and a test tube is usually used as a rapid diagnosis tool or a rapid detection tool in order to obtain a qualitative result quickly. Generally, the sample to be diagnosed or tested will usually have some risks, such as toxicity and infectivity. The used test tube is treated as medical waste.

However, the related art test tube has some drawbacks. For example, the tube and the cap of part test tube are split type designs, and the cap drops from the tube easily for material, the solution in the tube outwards flow, the polluted environment, harm staff's life safety. In addition, the tube part and the cap part of the test tube are designed as an integral body, but the sealing performance and the connection firmness are poor, and the cap part is easy to separate from the tube part under the action of external force, so that substances and solutions in the tube part can flow outwards.

At present to among the correlation technique, the cap that has the test tube and the condition that the material in easy separation, the pipe portion of pipe portion is outwards flowed out, lead to polluted environment, harm staff's life safety's problem, has not proposed effectual solution yet.

Disclosure of Invention

The invention aims to provide a biochemical test paper tube aiming at the defects in the prior art, so as to at least solve the problems of environmental pollution and life safety hazard of the test tube in the related technology.

In order to achieve the purpose, the invention adopts the technical scheme that:

the invention provides a biochemical test paper tube, which comprises a tube part and a cover part, wherein the cover part is in interpolation matching with the tube part;

the tube portion includes:

a solution chamber;

the test paper fixing part or the top of the sample receiving end of the biochemical test paper positioned in the test paper fixing part extends to the bottom end of the inner wall of the cover part under the condition that the cover part seals the tube part, the vertical interval between the test paper fixing part or the sample receiving end of the biochemical test paper positioned in the test paper fixing part and the top of the cover part is less than 2mm, the horizontal interval is arranged between the outer edge of the test paper fixing part and the inner wall of the tube part, and the horizontal interval is greater than the wall thickness of an inserted tube opening of the cover part;

the test paper fixing part is a biochemical test paper cavity, and the top end of the biochemical test paper cavity is communicated with the solution cavity; or

The test paper fixing part is a biochemical test paper container positioned by the clamping side wall in the solution cavity and the outer wall of the solution cavity, and the top end of the biochemical test paper container is provided with a communication hole communicated with a sample solution receiving end of biochemical test paper or the biochemical test paper in the biochemical test paper container extends out of the top end of the biochemical test paper container by a certain length; or

The test paper fixing part is a biochemical test paper container positioned by the clamping side wall in the solution cavity and the outer wall of the solution cavity, and after the top end of the biochemical test paper container is broken, a broken cross section of the biochemical test paper container is provided with a communicating hole communicated with a sample solution receiving end of biochemical test paper or the biochemical test paper positioned in the biochemical test paper container extends out of the top end of the biochemical test paper container for a certain length.

In one embodiment, the width of the reagent holding member is not greater than 2.8mm, and the depth of the reagent holding member is not less than 28 mm.

In one embodiment thereof, the cover further comprises:

a cavity formed by an inner surface of the cover portion bulging outward;

the test paper fixing part or the top of the sample receiving end of the biochemical test paper positioned in the test paper fixing part protrudes out of the horizontal plane of the pipe orifice by at least 1 mm.

In one embodiment, the device further comprises an opening prevention part;

the cover portion includes:

a stopper member provided on an outer wall of the lid portion;

the opening prevention part is arranged on the top of the tube part and/or the limiting part of the cover part.

In one embodiment, the longitudinal section of the cavity is trapezoidal, circular arc or triangular.

In one embodiment, the opening prevention member includes a counter bore provided at the top of the nozzle of the tube portion.

In one embodiment, the opening prevention member further comprises a chamfered portion provided on an outer wall of the stopper member;

wherein, in a case where the lid portion closes the tube portion, a width of a cross section of an upper end of the chamfered portion is smaller than a width of a cross section of a lower end of the chamfered portion.

In one embodiment, the opening prevention member further comprises:

the cover opening component is arranged in the counter bore, the first end of the cover opening component is located on the inner wall of the counter bore, and the second end of the cover opening component is located on the outer wall of the counter bore or located between the outer wall of the counter bore and the inner wall of the counter bore.

In one embodiment thereof, the cover further comprises:

a sealing member provided on an outer wall of the lid section;

a first fitting member provided on an outer wall of the lid portion and positioned above the sealing member;

the tube portion includes:

and a second fitting member provided on an inner wall of the tube portion, the second fitting member being fitted and connected to the first fitting member.

In one embodiment, the sealing member is an annular projection.

In one embodiment, the first engaging member is an annular projection, and the second engaging member is an annular groove.

In one embodiment, the number of the first fitting parts is several, and several first fitting parts are arranged at intervals along the axial direction of the cover part.

In one embodiment, the number of the second engaging parts is several, and several of the second engaging parts are arranged at intervals along the axial direction of the pipe portion.

In one embodiment, the biochemical test paper tube further comprises:

and a connection member connected to the tube portion and the cap portion, respectively.

In one embodiment, the biochemical test paper tube further comprises:

the biochemical test paper is arranged inside the test paper fixing part;

under the condition that the cover part seals the tube part, the sample solution receiving end of the biochemical test paper is close to the cover part, and a horizontal interval is formed between the sample solution receiving end of the biochemical test paper and the inner wall of the cover part.

In one embodiment, the biochemical test strip protrudes from the test strip fixing member.

In one embodiment, the length of the biochemical test paper protruding from the test paper fixing part is 1-5 mm.

In one embodiment, the biochemical test strip is an immunochromatographic test strip comprising:

a substrate;

a chromatographic membrane disposed on an upper surface of the substrate;

the water absorption pad is arranged on the lower surface of the base material;

wherein the chromatographic membrane and the absorbent pad are contacted at the end of the substrate and solution transfer is performed.

In one embodiment thereof, the end of the chromatographic membrane is a distance beyond the end of the substrate;

the tail end of the absorbent pad exceeds the tail end of the base material by a certain distance;

the end of the chromatographic membrane is contacted with the end of the absorbent pad and solution transfer is carried out.

In one embodiment, the chromatographic membrane is also arranged on the lower surface of the substrate, and the tail end of the chromatographic membrane and the tail end of the water absorption pad are contacted on the lower surface of the substrate and perform solution transmission.

In one embodiment, the absorbent pad is further disposed on the upper surface of the substrate, and the ends of the chromatographic membrane and the absorbent pad are in contact with each other on the upper surface of the substrate and perform solution transfer.

In one embodiment, the immunochromatographic test strip further comprises:

a conjugate pad disposed on the substrate, an end of the conjugate pad contacting a front end of the chromatographic membrane and delivering a solution to the chromatographic membrane;

a guide film disposed on the substrate, a distal end of the guide film contacting a front end of the conjugate pad and transferring a solution to the conjugate pad;

wherein the solution chromatography speed of the guide membrane is less than that of the binding pad.

In one embodiment, the guide film has a thickness of less than 0.15 mm.

In one embodiment, the immunochromatographic test strip further comprises:

a sample pad disposed on the substrate, a distal end of the sample pad contacting a front end of the guide membrane and transferring a solution to the guide membrane.

In one embodiment, the immunochromatographic test strip further comprises:

a sample pad disposed on the substrate, a distal end of the guide membrane contacting a front end of the sample pad and delivering a solution to the sample pad.

In one embodiment, the immunochromatographic test strip further comprises:

a sample limiting membrane disposed on the substrate, a distal end of the sample limiting membrane contacting a front end of the guide membrane and transferring a solution to the guide membrane.

In one embodiment, the liquid absorption saturation volume of the sample limiting film is 2-20 μ l.

In one embodiment, the immunochromatographic test strip further comprises:

and the filter pad is arranged on the base material, and the tail end of the guide membrane is in contact with the front end of the filter pad and transmits the solution to the filter pad.

In one embodiment, the immunochromatographic test strip further comprises:

and the water retaining cushion is arranged close to the front end of the guide film.

In one embodiment, the water-retaining pad of the immunochromatographic test strip fills the gap between the immunochromatographic test strip and the strip fixing member.

In one embodiment, the immunochromatographic test strip further comprises:

a transparent protective film covering at least the chromatographic carrier and the conjugate pad.

In one embodiment, the chromatographic membrane comprises a detection line and a quality control line which are arranged in sequence.

In one embodiment, the lower surface of the end of the absorbent pad is in contact with the upper surface of the end of the chromatographic membrane; or

The upper surface of the tail end of the water absorption pad is contacted with the lower surface of the tail end of the chromatographic membrane.

In one embodiment, the lower surface of the distal end of the conjugate pad is in contact with the upper surface of the leading end of the chromatographic membrane; or

The upper surface of the distal end of the conjugate pad is in contact with the lower surface of the leading end of the chromatographic carrier.

In one embodiment thereof, a lower surface of the end of the guide film is in contact with an upper surface of the front end of the bonding pad; or

An upper surface of a tip of the guide film is in contact with a lower surface of a front end of the bonding pad.

In one embodiment, a lower surface of a tip of the guide membrane is in contact with an upper surface of a front end of the filter pad; or

The upper surface of the end of the guide membrane is in contact with the lower surface of the front end of the filter pad.

In one embodiment, the lower surface of the distal end of the filter pad is in contact with the doping surface of the front end of the conjugate pad; or

The upper surface of the end of the filter pad is in contact with the lower surface of the front end of the conjugate pad.

In one embodiment thereof, a lower surface of the distal end of the sample pad is in contact with an upper surface of the leading end of the guide film; or

An upper surface of a distal end of the sample pad is in contact with a lower surface of a leading end of the guide film.

In one embodiment thereof, the lower surface of the distal end of the sample pad is in contact with the upper surface of the leading end of the conjugate pad; or

The upper surface of the distal end of the sample pad is in contact with the lower surface of the leading end of the conjugate pad.

In one embodiment thereof, a lower surface of the tip of the guide film is in contact with an upper surface of the front end of the sample pad; or

An upper surface of a tip of the guide film is in contact with a lower surface of a front end of the sample pad.

In one embodiment thereof, a lower surface of a tip end of the sample limiting membrane is in contact with an upper surface of a leading end of the guide membrane; or

An upper surface of a tip end of the sample limiting membrane is in contact with a lower surface of a leading end of the guide membrane.

In one embodiment, when the end of the absorbent pad is located on the upper surface of the base material and the front end of the absorbent pad is located on the lower surface of the base material:

the length of the absorbent pad on the upper surface of the base material is greater than that of the absorbent pad on the lower surface of the base material; or

The length of the absorbent pad on the upper surface of the base material is equal to that of the absorbent pad on the lower surface of the base material; or

The length of the absorbent pad on the upper surface of the substrate is smaller than that of the absorbent pad on the lower surface of the substrate.

In one embodiment, in the case where the front end of the chromatographic carrier is located on the upper surface of the substrate and the end of the chromatographic carrier is located on the lower surface of the substrate:

the length of the chromatographic membrane positioned on the upper surface of the substrate is greater than the length of the chromatographic membrane positioned on the lower surface of the substrate; or

The length of the chromatographic membrane positioned on the upper surface of the substrate is equal to the length of the chromatographic membrane positioned on the lower surface of the substrate; or

The length of the chromatographic membrane on the upper surface of the substrate is smaller than the length of the chromatographic membrane on the lower surface of the substrate.

In one embodiment, the inspection line and the quality control line are located on the upper surface of the substrate; or

The detection line is positioned on the upper surface of the substrate, and the quality control line is positioned on the lower surface of the substrate; or

The detection line and the quality control line are positioned on the lower surface of the substrate.

In one embodiment, the method further comprises:

the biochemical test paper is arranged inside the transparent hollow tube, and the transparent hollow tube is arranged inside the test paper fixing part.

In one embodiment, one end of the transparent hollow tube is a closed end.

In some of these embodiments, the strip fixing member is a strip cartridge including:

a base card, the base card comprising:

the biochemical test paper groove is arranged on the first end face of the bottom card and used for placing biochemical test paper strips;

the first sealing surface is arranged on the periphery of the biochemical test paper groove;

a first sealing member adhered to the first sealing surface such that the biochemical test strip groove forms a sealed space.

In some of these embodiments, the base card further comprises:

the sample solution adding hole is formed in the second end face of the bottom card and communicated with the biochemical test paper groove;

a second sealing surface disposed around the sample solution addition hole;

the sealed film single-layer test paper card further comprises:

a second sealing member bonded to the second sealing face such that the sample solution addition hole forms a sealed space.

In some of these embodiments, the base card further comprises:

the first crease part is arranged on the second end face of the bottom card and is close to the sample solution adding hole;

and after the bottom card is broken along the first folding part, a sample solution receiving end of a biochemical test strip arranged in the biochemical test strip groove is exposed to the broken section of the first folding part.

In some embodiments, after the bottom card is broken along the first folding part, the sample solution receiving end of the biochemical test strip disposed in the biochemical test strip slot extends outside the biochemical test strip slot by a length greater than 0.5 mm.

In some of these embodiments, the first crease member comprises:

a first crease element disposed at a second end face of the base card and proximate to the sample solution addition hole;

and the second folding elements are symmetrically arranged at two ends of the first folding element and are connected with the first folding element.

In some embodiments, a cavity is formed at an outer end of the biochemical test strip arranged in the biochemical test strip groove, where the outer end is located at an intersection of the first folding part and the biochemical test strip, and a ratio of a height of the cavity to a length of the outer end of the biochemical test strip is greater than 70%.

In some of these embodiments, the base card further comprises:

and the second folding part is arranged on the first end surface of the bottom card, is positioned in the biochemical test paper groove and corresponds to the first folding part.

In some of these embodiments, the base card is made of a transparent material; and/or

The first sealing member is a first sealing film comprising an aluminum foil film; and/or

The second sealing member is a second sealing film including an aluminum foil film.

In some of these embodiments, the base card further comprises:

the slide rail parts are arranged on two sides of the bottom card and extend from one side of the first crease part to the other side of the first crease part;

the test strip card box still includes:

the sliding component is connected with the sliding rail component in a sliding way;

after the bottom card is bent along the first crease part, the bottom card is divided into a first part and a second part, the first part and the second part are in a bent state, and the sliding part is initially positioned at the first part; after the second part is reset, the first part and the second part are in a horizontal state, one end of the sliding part is located at the first part, the other end of the sliding part is located at the second part, and the sliding part seals the first crease part.

In some of these embodiments, the base card further comprises:

the anti-falling parts are arranged at the two ends of the sliding rail part and used for limiting the sliding part.

By adopting the technical scheme, compared with the prior art, the invention has the following technical effects:

according to the biochemical test paper tube, the horizontal interval is formed between the test paper fixing part and the inner wall of the tube part, so that the biochemical test paper is prevented from contacting or forming an adherence wall with the inner wall of the tube part to influence the detection effect under the condition that the biochemical test paper is placed on the test paper fixing part.

Drawings

FIG. 1 is a schematic view of a biochemical test paper tube according to an embodiment of the present application (I);

FIG. 2 is a cross-sectional view (one) showing a closed state of a biochemical test paper tube according to an embodiment of the present application;

FIG. 3 is a top view (one) of an unclosed state of a biochemical test paper tube according to an embodiment of the present application;

FIG. 4 is a cross-sectional view (one) of an unclosed state of a biochemical test paper tube according to an embodiment of the present application;

FIG. 5 is a cross-sectional view (II) showing an unclosed state of a biochemical test paper tube according to an embodiment of the present application;

FIG. 6 is a sectional view showing a closed state of a biochemical test paper tube according to an embodiment of the present application;

FIG. 7 is a plan view of an unclosed state of a biochemical test paper tube according to an embodiment of the present application;

FIG. 8 is a cross-sectional view (III) of an unclosed state of a biochemical test paper tube according to an embodiment of the present application;

FIG. 9 is a schematic view of a biochemical test paper tube according to an embodiment of the present application (II);

FIG. 10 is a sectional view (III) showing a closed state of a biochemical test paper tube according to an embodiment of the present application;

FIG. 11 is a cross-sectional view (IV) of an unclosed state of a biochemical test paper tube according to an embodiment of the present application;

FIG. 12 is a schematic view (III) of a biochemical test paper tube according to an embodiment of the present application;

FIG. 13 is a sectional view (IV) showing a closed state of a biochemical test paper tube according to an embodiment of the present application;

FIG. 14 is a cross-sectional view (V) of an unclosed state of a biochemical test paper tube according to an embodiment of the present application;

FIG. 15 is a schematic view (IV) of a biochemical test paper tube according to an embodiment of the present application;

FIG. 16 is a sectional view (V) showing a closed state of a biochemical test paper tube according to an embodiment of the present application;

FIG. 17 is a sectional View (VI) showing a closed state of a biochemical test paper tube according to an embodiment of the present application;

FIG. 18 is a sectional View (VI) of an unclosed state of a biochemical test paper tube according to an embodiment of the present application;

FIG. 19 is a schematic view of an immunochromatographic test strip according to an embodiment of the present application (I);

FIG. 20 is a cross-sectional view of an immunochromatographic test strip according to an embodiment of the present application (I);

FIG. 21 is a cross-sectional view of a biochemical test paper tube (provided with biochemical test paper) according to an embodiment of the present application;

FIG. 22 is a schematic view of an immunochromatographic test strip according to an embodiment of the present application (II);

FIG. 23 is a sectional view of an immunochromatographic test strip according to an embodiment of the present application (II);

FIG. 24 is a schematic view (III) of an immunochromatographic test strip according to an embodiment of the present application;

FIG. 25 is a sectional view of an immunochromatographic test strip according to an embodiment of the present application (III);

FIG. 26 is a schematic view (IV) of an immunochromatographic test strip according to an embodiment of the present application;

FIG. 27 is a sectional view (IV) of the immunochromatographic test strip according to an embodiment of the present application;

FIG. 28 is a cross-sectional view of an immunochromatographic test strip according to an embodiment of the present application (V);

FIG. 29 is a cross-sectional view (one) of a transparent hollow tube according to an embodiment of the present application;

FIG. 30 is a cross-sectional view of a transparent hollow tube according to an embodiment of the present application (II);

FIG. 31 is a cross-sectional view of a biochemical test paper tube according to an embodiment of the present application (provided with a biochemical test paper sleeved with a transparent hollow tube);

FIG. 32 is a schematic view of a strip cartridge according to the present application;

FIG. 33 is a schematic view of a strip cartridge according to the present application (two);

FIG. 34 is a schematic view (one) of a base card according to the present application;

FIG. 35 is a schematic view of a base card fitted with a biochemical test strip according to the present application (one);

FIG. 36 is a schematic view of a strip cartridge according to the present application (III);

FIG. 37 is a schematic view of a strip cartridge according to the present application (IV);

FIG. 38 is a schematic view of a base card according to the present application (two);

FIG. 39 is a schematic view (III) of a base card according to the present application;

FIG. 40 is a schematic view of a base card equipped with a biochemical test strip according to the present application (two);

FIG. 41 is a schematic view of a base card equipped with a biochemical test strip according to the present application (III);

FIG. 42 is a schematic view (five) of a test strip cartridge according to the present application;

FIG. 43 is a schematic view of a strip cartridge according to the present application (sixth);

FIG. 44 is a schematic view (IV) of a base card according to the present application;

FIG. 45 is a schematic view (five) of a base card according to the present application;

FIG. 46 is a schematic view (IV) of a base card equipped with a biochemical test strip according to the present application;

FIG. 47 is a schematic view (V) of a base card equipped with a biochemical test strip according to the present application;

FIG. 48 is a schematic view (seventh) of a test strip cartridge according to the present application;

FIG. 49 is a schematic view (eight) of a test strip cartridge according to the present application;

FIG. 50 is a schematic view of a base card according to the present application (six);

FIG. 51 is a schematic view (seven) of a base card according to the present application;

FIG. 52 is a schematic View (VI) of a base card equipped with a biochemical test strip according to the present application;

FIG. 53 is a schematic view (seventh) of a base card equipped with a biochemical test strip according to the present application;

FIG. 54 is a schematic view (nine) of a strip cartridge according to the present application;

FIG. 55 is a schematic view (eight) of a base card according to the present application;

FIG. 56 is a schematic view (eight) of a base card equipped with a biochemical test strip according to the present application;

FIG. 57 is a schematic view (nine) of a base card equipped with a biochemical test strip according to the present application;

FIG. 58 is a schematic view of a base card according to the present application (nine);

FIG. 59 is a schematic view (ten) of a base card according to the present application;

fig. 60 is a cross-sectional view of a bottom card according to the present application.

Wherein the reference numerals are: 100. a biochemical test paper tube; 110. a tube portion; 111. a solution chamber; 112. a test paper fixing member; 113. a clamping side wall; 114. a second fitting member; 120. a cover portion; 121. a limiting component; 122. a cavity; 123. a sealing member; 124. a first fitting member; 130. a connecting member; 140. an opening prevention member; 141. a counter bore; 142. chamfering the corner; 143. a lid opening part;

200. immunochromatography test paper; 210. a substrate; 220. a chromatographic membrane; 221. detecting lines; 222. a quality control line; 230. a water absorbent pad; 240. a bonding pad; 250. a guide film; 260. a sample pad; 270. a sample limiting membrane; 280. a transparent protective film;

300. a transparent hollow tube;

400. a test paper card box; 410. bottom card; 411. a biochemical test paper groove; 412. a first sealing surface; 413. a sample solution addition well; 414. a second sealing surface; 415. a first crease member; 4151. a first crease element; 4152. a second creasing element; 416. a second creasing member; 417. a slide rail member; 418. an anti-drop component; 420. a first seal member; 430. a second seal member; 440. a sliding member.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

It should be noted that the embodiments and features of the embodiments may be combined with each other without conflict.

The invention is further described with reference to the following drawings and specific examples, which are not intended to be limiting.

Example 1

As shown in FIGS. 1 to 4, a tube 100 for biochemical test paper comprises a tube portion 110, a cap portion 120 and a connecting member 130, wherein the tube portion 110 and the cap portion 120 are connected by the connecting member 130, and the tube portion 110 and the cap portion 120 are connected by an insertion.

The tube portion 110 includes a solution chamber 111 and a test paper fixing member 112. The axial direction of the solution chamber 111 is coaxial with or parallel to the axial direction of the tube portion 110, and the solution chamber 111 is used for placing a solution such as a reaction solution. The axial direction of the test paper fixing part 112 is parallel to the axial direction of the solution chamber 111, and the test paper fixing part 112 is used for placing biochemical test paper.

Wherein, there is a horizontal interval, at least 0.5mm, between the outer edge of the test paper fixing part 112 and the inner wall of the tube part 110, for preventing the biochemical test paper placed in the test paper fixing part 112 from contacting with the inner wall of the tube part 110 or forming adherence.

Wherein the width of the test strip fixing member 112 (the diameter direction of the tube portion 110) is not more than 2.8mm, and the depth of the test strip fixing member 112 is not less than 28mm

When the cap 120 closes the tube 110, the top of the solution chamber 111 and the top of the strip fixing member 112 communicate with each other.

Further, in the case where the cover part 120 closes the tube part 110, there is a horizontal interval of at least 0.5mm between the inner edge of the test strip fixing member 112 and the inner wall of the cover part 120, for preventing the biochemical test strips placed in the test strip fixing member 112 from contacting the inside of the cover part 120 or forming adhesion.

In some embodiments, in the case where the cap 120 closes the tube portion 110, the outer edge of the reagent fixing member 112 is horizontally spaced from the inner wall of the cap 120 by at least 0.5mm, so as to prevent the biochemical reagent placed in the reagent fixing member 112 from contacting the inside of the cap 120 or adhering thereto.

In some of these embodiments, in the case where the cover part 120 closes the tube part 110, there is a vertical interval between the top wall of the test paper fixing member 112 and the bottom wall of the cover part 120, which is less than 2 mm.

Wherein, the solution cavity 111 is a regular-shaped cavity (such as a circular cavity, a rectangular cavity, a trapezoidal cavity) or an irregular-shaped cavity. The reagent holding member 112 may be a regular-shaped chamber (e.g., a circular chamber, a rectangular chamber, a trapezoidal chamber) or an irregular shape.

The test paper fixing member 112 is a biochemical test paper cavity, and the top end of the biochemical test paper fixing member is communicated with the solution cavity 111.

In one embodiment, the solution cavities 111 may be several, the axes of several solution cavities 111 are parallel, at least one solution cavity 111 is used for placing biochemical reaction reagents or biochemical reaction solutions, and at least one solution cavity 111 is used for placing functional reaction reagents. The functional reagent includes, but is not limited to, degrading enzyme, lysis solution, probe, buffer solution, diluent, etc., or a reagent for performing a subsequent reaction after the biochemical reaction is completed.

In one embodiment, the number of the test strip fixing parts 112 may be several, the axes of several test strip fixing parts 112 are parallel, and each test strip fixing part 112 has a biochemical test strip placed therein, so that different indexes of the same sample can be detected at the same time.

The plurality of test strip fixing members 112 are disposed around the axial direction of the tube 110.

The cover part 120 includes a stopper part 121 and a cavity 122, wherein the stopper part 121 is disposed at an outer wall of the cover part 120, and the cavity 122 is formed by an inner surface of the cover part 120 protruding outward.

Wherein, the limiting part 121 is a limiting ring.

Wherein, the longitudinal section of the cavity 122 is trapezoidal, circular arc or triangular.

The connection member 130 is connected to the tube 110 and the cap 120, respectively, so that the tube 110 and the cap 120 form a one-piece structure.

The connection member 130 may be a connection bar, one end of which is connected to the tube 110 and the other end of which is connected to the cap 120.

Through the biochemical test paper tube of this embodiment, utilize the fixed part of specially designed test paper, make the biochemical test paper of placing in the fixed part of test paper neither contact the inner wall of pipe portion, do not contact the inside of lid again, avoid appearing biochemical test paper and appear the adherence.

Example 2

This embodiment is a modified embodiment of embodiment 1, and is different from embodiment 1 in that: the strip fixing member 112 is different.

As shown in fig. 5, the test paper fixing member 112 is a biochemical test paper container positioned by the clamping side wall 113 inside the solution chamber 111 and the outer wall of the solution chamber 111, and a communication hole is formed at the top end of the biochemical test paper container and connected to a sample solution receiving end of the biochemical test paper or the biochemical test paper in the biochemical test paper container extends out of the top end of the biochemical test paper container by a certain length.

Example 3

This embodiment is a modified embodiment of embodiment 2, and is different from embodiment 2 in that: the strip fixing member 112 is different.

As shown in fig. 6 to 8, the test paper fixing member 112 is a biochemical test paper container positioned by the clamping side wall 113 inside the solution cavity 111 and the outer wall of the solution cavity 111, and after the top end of the biochemical test paper container is broken, a broken cross section of the biochemical test paper container has a communication hole communicated with a sample solution receiving end of the biochemical test paper or the biochemical test paper in the biochemical test paper container extends from the top end of the biochemical test paper container for a certain length.

Example 4

As shown in FIGS. 9 to 11, a biochemical test paper tube 100 includes a tube part 110, a cap part 120, a connecting part 130, and an opening preventing part 140, wherein the tube part 110 and the cap part 120 are connected by the connecting part 130, and the opening preventing part 140 is provided on the top of the tube part 110. However, when the cover 120 closes the tube 110, the cover 120 cannot be removed from the tube 110 by the opening prevention member 140.

The structure and connection manner of the tube 110, the cover 120 and the connection member 130 are substantially the same as those of embodiment 1, and are not described again here.

The opening prevention member 140 includes a counter bore 141, the counter bore 141 being provided at the top of the tube portion 110 and capable of being engaged with the stopper member 121 of the cap portion 120, the stopper member 121 being provided at the counter bore 141 with the upper surface of the stopper member 121 being at the same level as the upper surface of the counter bore 141 in a state where the cap portion 120 closes the tube portion 110.

The method of use of this example is as follows: placing the biochemical test paper into the test paper fixing part 112, and enabling a sample solution receiving end of the biochemical test paper to be arranged upwards; placing a reaction solution into the solution cavity 111, placing a sample to be detected, such as a throat swab, into the solution cavity 111, closing the tube part 110 with the cover part 120, and immersing the limiting part 121 of the cover part 120 into the counterbore 141; after the reaction in the solution cavity 111 is completed, the biochemical test paper tube 100 is inclined, so that the reaction solution contacts the biochemical test paper, the reaction solution performs biochemical action on the biochemical test paper, and the detection result can be obtained by observing the biochemical test paper; after the detection result is observed, the biochemical test paper tube 100 can be directly treated as medical waste without worrying about leakage of the substance in the biochemical test paper tube 100.

Through the test tube that is provided with of this embodiment and prevents opening the part, seal the pipe portion at the cap after, can't avoid the intraductal material of biochemical test paper to leak with cap and pipe portion separation, avoid polluted environment, harm life health.

Example 5

As shown in FIGS. 12 to 14, a biochemical test paper tube 100 includes a tube part 110, a lid part 120, a connecting member 130, and an opening prevention member 140, wherein the tube part 110 and the lid part 120 are connected by the connecting member 130, and the opening prevention member 140 is provided on the top of the tube part 110 and the outer wall of the lid part 120. However, when the cover 120 closes the tube 110, the cover 120 cannot be removed from the tube 110 by the opening prevention member 140.

The opening prevention member 140 includes a counterbore 141 and a chamfered portion 142, the counterbore 141 being provided at the top of the tube portion 110, and the chamfered portion 142 being provided at the outer wall of the stopper member 121.

The chamfer portion 142 and the limiting member 121 are designed as an integral structure.

In a case where the cover part 120 closes the tube part 110, a width of a cross section of a first end (upper end) of the chamfered part 142 is smaller than a width of a cross section of a second end (lower end) of the chamfered part 142.

When the cover 120 closes the tube 110, the stopper member 121 is provided to the counterbore 141 together with the chamfered portion 142, and the upper surface of the stopper member 121, the upper surface of the chamfered portion 142, and the upper surface of the counterbore 141 are located on the same horizontal plane.

The using method of this embodiment is basically the same as that of embodiment 1, and is not described herein again.

In the present embodiment, in the case where the cap closes the tube, the cap cannot be separated from the tube by the dual action of the counterbore and the chamfered portion; due to the presence of the chamfered portion, it is not possible to provide a stress point, and even if an external force is forcibly applied to the counterbore and the chamfered portion, the cap portion cannot be separated from the tube portion.

Example 6

As shown in FIGS. 15 to 16, a biochemical test paper tube 100 includes a tube part 110, a cap part 120, a connecting part 130, and an opening preventing part 140, wherein the tube part 110 and the cap part 120 are connected by the connecting part 130, and the opening preventing part 140 is provided on the top of the tube part 110. However, when the cover 120 closes the tube 110, the cover 120 cannot be removed from the tube 110 by the opening prevention member 140.

The opening prevention member 140 includes a counter bore 141 and a cover opening member 143.

The counter bore 141 is provided at the top of the tube 110 and is capable of engaging with the stopper 121 of the cap 120, and when the cap 120 closes the tube 110, the stopper 121 is provided in the counter bore 141, and the upper surface of the stopper 121 and the upper surface of the counter bore 141 are at the same level.

Wherein the cap member 143 is provided on an upper surface or inside of the counterbore 141 for separating the cap 120 from the tube 110 by the cap member 143 under certain circumstances.

In one embodiment, the cap member 143 is disposed through the counterbore 141. Specifically, a first end of the cap member 143 is positioned at an inner wall of the counterbore 141, a second end of the cap member 143 is positioned at an outer wall of the counterbore 141, and the cap part 120 is tilted by passing an auxiliary tool, such as a pry bar, through the cap member 143 to separate the cap part 120 from the tube part 110.

In one embodiment, the cap-opening part 143 is provided on an upper surface of the counterbore 141. Specifically, a first end of the cap member 143 is positioned at an inner wall of the counterbore 141, a second end of the cap member 143 is positioned between the inner wall and an outer wall of the counterbore 141, and the cover part 120 is tilted by passing an auxiliary tool, such as a pry piece, through the cap member 143 to separate the cover part 120 from the tube part 110.

The present embodiment is used in substantially the same manner as in embodiment 1, except that after the detection result is obtained, the lid portion 120 is separated from the tube portion 110 by the lid-opening member 143 to recover the solution or substance in the biochemical paper tube 100.

Example 7

As shown in FIGS. 17 to 18, a biochemical test paper tube 100 includes a tube part 110, a cap part 120, a connecting part 130, and an opening preventing part 140, wherein the tube part 110 and the cap part 120 are connected by the connecting part 130, and the opening preventing part 140 is provided on the top of the tube part 110. However, when the cover 120 closes the tube 110, the cover 120 cannot be removed from the tube 110 by the opening prevention member 140.

The structure and connection manner of the connection member 130 and the opening prevention member 140 are substantially the same as those of embodiments 2 to 4, and are not described herein again.

The tube portion 110 includes a solution chamber 111, a strip fixing member 112, and a second fitting member 114.

The structure and connection manner of the solution chamber 111 and the test strip fixing member 112 are substantially the same as those in embodiment 1, and are not described herein again.

Second fitting parts 114 are provided on the inner wall of the top of pipe part 110, and second fitting parts 114 are provided at intervals in the axial direction of pipe part 110.

The cover portion 120 includes a stopper member 121, a cavity 122, a sealing member 123, and a first fitting member 124.

The structure and connection manner of the limiting part 121 and the cavity 122 are substantially the same as those of embodiment 1, and are not described herein again.

The sealing member 123 and the first fitting member 124 are provided at intervals in the axial direction of the cover 120. When the lid 120 closes the tube 110, the sealing member 123 is positioned below the lid 120, and the first fitting member 124 is positioned above the sealing member 123.

When the lid 120 closes the tube 110, the sealing member 123 seals the top of the tube 110, and the first fitting member 124 is fitted to the second fitting member 114, so that the lid 120 and the tube 110 are tightly coupled.

In one embodiment, the sealing member 123 is an annular projection having an outer diameter equal to the inner diameter of the top of the tube portion 110.

In one embodiment, the first engagement member 124 is an annular projection having an outer diameter greater than the inner diameter of the top of the tube portion 110; the second engagement member 114 is an annular groove that mates with the first engagement member 124.

Through the sealing member, first gomphosis part and the second gomphosis part of this embodiment, further improve the inseparable degree of being connected between cap and the pipe portion, greatly improved the resistance with cap and pipe portion separation, effectively prevent the intraductal solution of biochemical test paper and leak, avoid the polluted environment, prevent to endanger life health.

Example 8

This example relates to the biochemical test paper placed in the biochemical test paper tube of examples 1 to 7.

In this example, a biochemical test strip is exemplified as an immunochromatographic test strip.

As shown in fig. 19 to 20, an immunochromatographic test strip 200 includes a substrate 210, a chromatographic membrane 220, a water absorption pad 230, a binding pad 240, and a guide membrane 250, wherein the guide membrane 250, the binding pad 240, the chromatographic membrane 220, and the water absorption pad 230 are sequentially disposed on the substrate 210.

The immunochromatographic test strip 200 is provided to protrude from the strip fixing member 112. Generally, the immunochromatographic test strip 200 protrudes from the strip-fixing member 112 to a degree of 1mm to 5mm, and preferably has a length of 2mm to 3 mm.

When the cap 120 closes the tube 110, the sample solution receiving end of the immunochromatographic test strip 200 extends into the cavity 122 of the cap 120.

Further, in the case where the cap 120 closes the tube portion 110, the sample solution receiving end of the immunochromatographic test strip 200 is horizontally spaced from the inner wall of the cap 120 by at least 0.5 mm.

The substrate 210 is made of plastic, such as a non-setting adhesive plastic.

The guide film 250 is disposed on the upper surface of the substrate 210, i.e., the lower surface of the guide film 250 and the upper surface of the substrate 210 are connected, e.g., bonded. The end of the guide film 250 is in contact with the front end of the conjugate pad 240, and the guide film 250 transfers the solution to the conjugate pad 240.

The upper surface of the end of the guide film 250 is in contact with the lower surface of the front end of the bonding pad 240, or the lower surface of the end of the guide film 250 is in contact with the upper surface of the front end of the bonding pad 240.

Wherein the guide membrane 250 is made of a cellulose membrane.

Wherein the thickness of the guide film 250 is less than 0.15 mm.

The bonding pad 240 is disposed on the upper surface of the substrate 210, i.e., the lower surface of the bonding pad 240 is connected to, e.g., adhered to, the upper surface of the substrate 210. The end of the conjugate pad 240 contacts the front end of the chromatographic carrier 220, and the conjugate pad 240 transfers the solution to the chromatographic carrier 220. Specifically, the upper surface of the end of the conjugate pad 240 is in contact with the lower surface of the front end of the chromatographic carrier 220, or the lower surface of the end of the conjugate pad 240 is in contact with the upper surface of the front end of the chromatographic carrier 220.

Wherein, the bonding pad 240 is a gold pad.

The bonding pad 240 is made of glass fiber, polyester film, cellulose filter paper, non-woven fabric, or the like.

Wherein the solution chromatography speed of the guide membrane 250 is lower than that of the conjugate pad 240.

The chromatographic carrier 220 is disposed on at least the upper surface of the substrate 210, i.e., the lower surface of the chromatographic carrier 220 is attached, e.g., adhered, to the upper surface of the substrate 210. The end of the chromatographic carrier 220 contacts the end of the absorbent pad 230, and the chromatographic carrier 220 transfers the solution to the absorbent pad 230.

The chromatographic membrane 220 is further provided with a detection line 221 and a quality control line 222, which are sequentially arranged along the front end to the tail end of the chromatographic membrane 220.

Wherein, the chromatographic membrane 220 is made of a nitrocellulose membrane.

The absorbent pad 230 is disposed on at least the lower surface of the substrate 210, i.e., the upper surface of the absorbent pad 230 is connected to, e.g., adhered to, the lower surface of the substrate 210. The end of the absorbent pad 230 contacts the end of the chromatographic carrier 220.

Wherein the absorbent pad 230 is absorbent paper.

Wherein the ends of the chromatographic carrier 220 and the absorbent pad 230 are contacted at the end of the substrate 210 and solution transfer is performed.

In the first embodiment of this example, the end of the chromatographic carrier 220 is beyond the end of the substrate 210 by a certain distance, the end of the absorbent pad 230 is beyond the end of the substrate 210 by a certain distance, and the end of the chromatographic carrier 220 and the end of the absorbent pad 230 are in contact and perform solution transfer, that is, the lower surface of the end of the chromatographic carrier 220 and the upper surface of the end of the absorbent pad 230 are in contact and perform solution transfer. In this embodiment, the chromatographic carrier 220, the substrate 210 and the absorbent pad 230 form a sandwich structure.

In the second embodiment of this embodiment, the chromatographic carrier 220 is further disposed on the lower surface of the substrate 210, i.e., the end of the chromatographic carrier 220 is bent downward at the end of the substrate 210. Specifically, the upper surface of the end of the chromatographic carrier 220 contacts the upper surface of the end of the absorbent pad 230 and solution transfer is performed, or the lower surface of the end of the chromatographic carrier 220 contacts the lower surface of the end of the absorbent pad 230 and solution transfer is performed.

In this embodiment, the length of the chromatographic membrane 220 located on the upper surface of the substrate 210 is greater than the length of the chromatographic membrane 220 located on the lower surface of the substrate 210; alternatively, the length of the chromatographic membrane 220 located on the upper surface of the substrate 210 is equal to the length of the chromatographic membrane 220 located on the lower surface of the substrate 210; alternatively, the length of the chromatographic carrier 220 located on the upper surface of the substrate 210 is less than the length of the chromatographic carrier 220 located on the lower surface of the substrate 210.

Preferably, the length of the chromatographic carrier 220 located on the upper surface of the substrate 210 is greater than the length of the chromatographic carrier 220 located on the lower surface of the substrate 210

In the third embodiment of this embodiment, the absorbent pad 230 is also disposed on the upper surface of the base material 210, i.e. the end of the absorbent pad 230 is bent upward at the end of the base material 210. Specifically, the upper surface of the end of the absorbent pad 230 contacts the upper surface of the end of the chromatographic carrier 220 and performs solution transfer, or the lower surface of the end of the absorbent pad 230 contacts the lower surface of the end of the chromatographic carrier 220 and performs solution transfer.

In this embodiment, the length of the absorbent pad 230 on the upper surface of the substrate 210 is greater than the length of the absorbent pad 230 on the lower surface of the substrate 210; alternatively, the length of the absorbent pad 230 on the upper surface of the substrate 210 is equal to the length of the absorbent pad 230 on the lower surface of the substrate 210; alternatively, the length of the absorbent pad 230 on the upper surface of the substrate 210 is less than the length of the absorbent pad 230 on the lower surface of the substrate 210.

Preferably, the length of the absorbent pad 230 on the upper surface of the substrate 210 is smaller than the length of the absorbent pad 230 on the lower surface of the substrate 210.

In addition, in order to ensure that the end of the chromatographic carrier 220 is in contact with the end of the absorbent pad 230, a thin film is provided between the end of the chromatographic carrier 220 and the end of the absorbent pad 230. The membrane covers the chromatographic carrier 220 and the absorbent pad 230 so that the chromatographic carrier 220 and the absorbent pad 230 are kept in contact.

In this embodiment, the length of the immunochromatographic test strip 200 is 2cm to 4cm, preferably 2.8cm, 3.0cm, 3.2cm, and 3.5 cm.

The method of use of this example is as follows: as shown in fig. 21, the immunochromatographic test strip 200 is placed in the strip fixing member 112 of the biochemical test strip tube 100 such that the sample solution receiving end of the immunochromatographic test strip 200 faces upward (i.e., the guide membrane 250); putting a solution to be reacted into the solution cavity 111 of the biochemical test paper tube 100, and putting a sample to be detected; after the solution in the solution cavity 111 finishes the reaction, the biochemical test paper tube 100 is tilted to make the reacted solution contact the sample solution receiving end of the immunochromatographic test paper 200, and the solution is rapidly adsorbed to the chromatographic membrane 220 for color development under the action of the water absorption pad 230.

Example 9

As shown in fig. 22-23, an immunochromatographic test strip 200 includes a substrate 210, a chromatographic membrane 220, a water-absorbing pad 230, a conjugate pad 240, a guide membrane 250, and a sample pad 260, wherein the sample pad 260, the guide membrane 250, the conjugate pad 240, the chromatographic membrane 220, and the water-absorbing pad 230 are disposed on the substrate 210.

The connection relationship, structure and composition of the substrate 210, the chromatographic membrane 220, the absorbent pad 230 and the conjugate pad 240 are substantially the same as those of embodiment 1, and are not repeated herein.

Sample pad 260 is disposed on the upper surface of substrate 210, i.e., the lower surface of sample pad 260 and the upper surface of substrate 210 are attached, e.g., bonded.

The sample pad 260 is made of glass fiber, polyester film, cellulose filter paper, nonwoven fabric, or the like.

In the first embodiment of this embodiment, the end of the sample pad 260 is in contact with the front end of the guide membrane 250, and the sample pad 260 transfers the solution to the guide membrane 250. Specifically, the upper surface of the end of the sample pad 260 contacts the lower surface of the front end of the guide film 250, or the lower surface of the end of the sample pad 260 contacts the upper surface of the front end of the guide film 250.

In the second embodiment of this embodiment, the front end of the sample pad 260 contacts the end of the guide membrane 250, and the guide membrane 250 transfers the solution to the sample pad 260. Specifically, the upper surface of the end of the guide film 250 is in contact with the lower surface of the front end of the sample pad 260, or the lower surface of the end of the guide film 250 is in contact with the upper surface of the front end of the sample pad 260.

The end of sample pad 260 contacts the front end of conjugate pad 240, and sample pad 260 transfers the solution to conjugate pad 240. Specifically, the upper surface of the end of sample pad 260 contacts the lower surface of the front end of conjugate pad 240, or the lower surface of the end of sample pad 260 contacts the upper surface of the front end of conjugate pad 240.

In the third embodiment of this embodiment, as shown in FIGS. 17 to 18, the immunochromatographic test strip 200 includes two guide membranes 250 disposed on the front and rear sides of the sample pad 260, respectively, i.e., the end of the first guide membrane 250 contacts the front end of the sample pad 260, and the first guide membrane 250 transfers a solution to the sample pad 260. Specifically, the upper surface of the end of the first guide film 250 contacts the lower surface of the front end of the sample pad 260, or the lower surface of the end of the first guide film 250 contacts the upper surface of the front end of the sample pad 260.

The end of the sample pad 260 contacts the second guide membrane 250, and the sample pad 260 transfers the solution to the second guide membrane 250. The upper surface of the end of the sample pad 260 contacts the lower surface of the front end of the second guide film 250, or the lower surface of the end of the sample pad 260 contacts the upper surface of the front end of the second guide film 250.

Wherein, in the case that there is only one guide film 250, the guide film 250 may be a first guide film; in the case where the guide membranes 250 are two, the guide membrane 250 near the chromatographic carrier 220 may be a first guide membrane, and the guide membrane 250 far from the chromatographic carrier 220 may be a second guide membrane.

In this embodiment, the solution chromatography speed of the sample pad 260 is greater than that of the guide membrane 250.

In this embodiment, the length of the immunochromatographic test strip 200 is 2cm to 4cm, preferably 3.2cm and 3.5 cm.

The using method of this embodiment is basically the same as that of embodiment 5, and is not described herein again.

Example 10

As shown in fig. 24 to 25, an immunochromatographic test strip 200 includes a base material 210, a chromatographic membrane 220, a water absorption pad 230, a binding pad 240, a guide membrane 250, and a sample limiting membrane 270, wherein the sample limiting membrane 270, the guide membrane 250, the binding pad 240, the chromatographic membrane 220, and the water absorption pad 230 are sequentially disposed on the base material 210.

The connection relationship, structure and composition of the substrate 210, the chromatographic membrane 220, the absorbent pad 230, the combination pad 240 and the guide membrane 250 are substantially the same as those of embodiment 5, and are not repeated herein.

The sample limiting membrane 270 is disposed on the upper surface of the substrate 210, i.e., the lower surface of the sample limiting membrane 270 is attached, e.g., adhered, to the upper surface of the substrate 210. The end of the sample limiting membrane 270 is in contact with the front end of the guide membrane 250, and the sample limiting membrane 270 transfers the solution to the guide membrane 250. Specifically, the upper surface of the end of the sample limiting membrane 270 is in contact with the lower surface of the front end of the guide membrane 250, or the lower surface of the end of the sample limiting membrane 270 is in contact with the upper surface of the front end of the guide membrane 250.

Wherein, the liquid absorption saturation volume of the sample limiting film 270 is 2-20 mul, and the sample limiting film can absorb trace samples.

The sample limiting film 270 is made of glass fiber, polyester film, cellulose filter paper, or the like.

In this embodiment, the length of the immunochromatographic test strip 200 is 2cm to 4cm, preferably 3.3cm, 3.5cm, and 3.7 cm.

Example 11

As shown in fig. 26 to 27, an immunochromatographic test strip 200 includes a substrate 210, a chromatographic membrane 220, a water-absorbent pad 230, a conjugate pad 240, a guide membrane 250, a sample pad 260, and a sample limiting membrane 270, wherein the sample limiting membrane 270, the guide membrane 250, the sample pad 260, the conjugate pad 240, the chromatographic membrane 220, and the water-absorbent pad 230 are disposed on the substrate 210.

The connection relationship, structure and composition of the substrate 210, the chromatographic membrane 220, the absorbent pad 230, the conjugate pad 240, the guide membrane 250 and the sample pad 260 are substantially the same as those of the second and third embodiments of example 6, and are not repeated herein.

In this embodiment, the length of the immunochromatographic test strip 200 is 2cm to 4cm, preferably 3.6cm and 3.8 cm.

Example 12

As shown in fig. 28, an immunochromatographic test strip 200 includes a substrate 210, a chromatographic membrane 220, a water absorption pad 230, a conjugate pad 240, a guide membrane 250, and a transparent protective membrane 280, wherein the guide membrane 250, the conjugate pad 240, the chromatographic membrane 220, and the water absorption pad 230 are sequentially disposed on the substrate 210.

The connection relationship, structure and composition of the substrate 210, the chromatographic membrane 220, the absorbent pad 230, the combination pad 240 and the guide membrane 250 are substantially the same as those in embodiment 1, and are not repeated herein.

The lower surface of the transparent protective film 280 covers at least the conjugate pad 240 and the chromatographic carrier 220.

In this embodiment, the transparent protection film 280 can prevent the binding pad 240 and the chromatographic carrier 220 from contacting with the exogenous aqueous mixture, thereby improving the accuracy of the detection result of the chromatographic strip.

The transparent protective film 280 may be applied to the immunochromatographic test strips of examples 8 to 11.

Example 13

As shown in fig. 29, the immunochromatographic test strip 200 further includes a transparent hollow tube 300, and the immunochromatographic test strip 200 is wrapped inside the transparent hollow tube 300 by the transparent hollow tube 300, that is, the immunochromatographic test strip 200 is disposed inside the transparent hollow tube 300.

The inner surface of the transparent hollow tube 300 is a hydrophobic surface.

The first end of the transparent hollow tube 300 is a closed end, and the second end thereof is an open end, which is provided to facilitate the movement of the immunochromatographic test strip 200 from the open end to the inside of the transparent hollow tube 300.

In addition, the sample solution receiving end of the immunochromatographic test strip 200 is located at the open end of the transparent hollow tube 300.

The transparent hollow tube 300 is made of a transparent material, such as plastic or thermoplastic resin, so as to facilitate observation of the detection or diagnosis result of the immunochromatographic test strip 200.

In one embodiment, as shown in fig. 30, the width of the cross-section of the second end of the open end of the transparent hollow tube 300 is greater than the inner diameter of the cross-section of the first end of the open end. Preferably, the width of the cross-section of the open end of the transparent hollow tube 300 decreases from the second end of the open end to the first end of the open end.

As shown in fig. 31, the immunochromatographic test strip 200 fitted with the transparent hollow tube 300 is placed in the strip fixing member 112 of the biochemical test strip tube 100, and the immunochromatographic test strip 200 is prevented from moving in the strip fixing member 112.

In addition, the use of the transparent hollow tube 300 prevents the immunochromatographic test strip 200 from directly contacting the inner surface of the strip fixing member 112, and prevents the surface tension of the inner surface of the strip fixing member 112 from affecting the adsorption rate of the immunochromatographic test strip 200.

Example 14

This embodiment relates to the test paper fixing member in the biochemical test paper tube of embodiments 1 to 7.

In this embodiment, a test strip fixing member is described as an example of a test strip cartridge.

As shown in fig. 32 to 33, a strip cartridge 400 includes a bottom card 410 and a first sealing member 420. The first sealing member 420 covers a first end surface of the bottom card 410, and is used for sealing the biochemical test paper in the bottom card 410.

As shown in FIG. 34, the bottom card 410 includes a biochemical test paper slot 411 and a first sealing surface 412. Wherein, the biochemical test paper slot 411 is arranged on the first end surface of the bottom card 410 and is used for placing biochemical test paper; the first sealing surface 412 is disposed around the biochemical test paper slot 411 for adhering the first sealing member 420.

In some embodiments, the bottom card 410 is made of a transparent material, such as plastic, to facilitate viewing of the detection process.

The first sealing member 420 is adhered to the first sealing surface 412 for forming a sealed space for the biochemical test paper slot 411.

In some of these embodiments, the first sealing member 420 is a first sealing membrane that includes at least an aluminum foil membrane.

As shown in FIG. 35, the immunochromatographic test strip 200 is placed inside the biochemical test strip slot 411, and the length of the immunochromatographic test strip 200 is smaller than that of the biochemical test strip slot 411.

The method of use of this example is as follows: the first sealing member 420 is torn along one end, and the sample solution is added to the sample solution receiving end of the immunochromatographic test strip 200 located in the biochemical test strip slot 411, and then waiting for observation.

Example 15

This embodiment is a modification of embodiment 14, and as shown in fig. 36 to 37, a strip cartridge 400 includes a bottom card 410, a first sealing member 420, and a second sealing member 430. The first sealing member 420 covers a first end surface of the bottom card 410, the second sealing member 430 covers a second end surface of the bottom card 410, and the first sealing member 420 and the second sealing member 430 are used to keep the biochemical test paper in the bottom card 410 in a sealed space, so as to keep the biochemical test paper dry.

The structure and connection relationship of the first sealing member 420 are substantially the same as those of embodiment 14, and are not described herein again.

As shown in FIGS. 38 to 39, the base card 410 includes a biochemical test paper slot 411, a first sealing surface 412, a sample solution addition hole 413, and a second sealing surface 414. Wherein, the biochemical test paper slot 411 is arranged on the first end surface of the bottom card 410 and is used for placing biochemical test paper; the first sealing surface 412 is arranged around the biochemical test paper slot 411 and is used for bonding the first sealing part 420; the sample solution adding hole 413 is disposed on a second end surface (the second end surface is disposed opposite to the first end surface, that is, the first end surface is an upper side surface, and the second end surface is a lower side surface) of the bottom card 410, and is communicated with the biochemical test paper slot 411, and is used for adding the sample solution to the biochemical test paper in the biochemical test paper slot 411 through the sample solution adding hole 413; the second sealing surface 414 is disposed around the sample solution adding hole 413 to adhere the second sealing member 430.

Wherein, the length of the sample solution adding hole 413 is smaller than the length of the biochemical test paper slot 411, and the sample solution adding hole 413 and the biochemical test paper slot 411 are arranged in a staggered way, namely, the lower part of the sample solution adding hole 413 is communicated with the upper part of the biochemical test paper slot 411.

In some of these embodiments, the width of the sample solution addition hole 413 is smaller than the width of the biochemical test paper slot 411.

The second sealing member 430 is adhered to the second sealing surface 414 to seal the sample solution adding hole 413, so that a sealed space is formed inside the bottom card 410, and the biochemical test paper placed in the biochemical test paper slot 411 is in a dry environment.

In some of these embodiments, the second sealing member 430 is a second sealing film that includes at least an aluminum foil film.

As shown in fig. 40 to 41, the immunochromatographic test strip 200 is placed inside the biochemical test strip slot 411, and the sample solution receiving end of the immunochromatographic test strip 200 is located at the communication position between the sample solution adding hole 413 and the biochemical test strip slot 411, so that the sample solution directly contacts the immunochromatographic test strip 200.

The method of use of this example is as follows: the second sealing member 430 is removed, and the sample solution is added to the immunochromatographic test strip 200 located in the biochemical test strip slot 411 through the sample solution addition hole 413, and then waits for observation.

Example 16

This embodiment is a modification of embodiment 15, and as shown in fig. 42 to 43, a strip cartridge 400 includes a bottom card 410, a first sealing member 420, and a second sealing member 430. The first sealing member 420 covers a first end surface of the bottom card 410, the second sealing member 430 covers a second end surface of the bottom card 410, and the first sealing member 420 and the second sealing member 430 are used to keep the biochemical test paper in the bottom card 410 in a sealed space, so as to keep the biochemical test paper dry.

The structure and connection relationship of the first sealing part 420 and the second sealing part 430 are substantially the same as those of embodiment 15, and are not described herein again.

As shown in FIGS. 44 to 47, the base card 410 includes a biochemical test paper bath 411, a first sealing surface 412, a sample solution addition hole 413, a second sealing surface 414, and a first folding member 415.

The structures and the connection relationships of the biochemical test paper slot 411, the first sealing surface 412, the sample solution adding hole 413, and the second sealing surface 414 are substantially the same as those in embodiment 15, and are not described herein again.

The first folding member 415 is disposed on the second end surface of the bottom card 410, and is disposed near the sample solution adding hole 413, and is used for folding the bottom card 410 at the first folding member 415, so that the sample solution receiving end of the immunochromatographic test strip 200 located in the bottom card 410 is exposed at the folded section of the first folding member 415.

Wherein the first crease member 415 comprises a first crease element 4151 and a second crease element 4152. Wherein the first folding member 4151 is disposed at the second end surface of the bottom card 410 and is disposed near the sample solution adding hole 413; the second flap member 4152 is symmetrically disposed at both ends of the first flap member 4151 (i.e., at the third end surface (left side surface) and the fourth end surface (right side surface) of the bottom card 410), and is connected to the first flap member 4151.

In some of these embodiments, the first flap member 4151 is a transverse fold and the second flap member 4152 is a vertical fold, enabling one end of the bottom card 410 to be quickly folded at the first fold section 415.

In some embodiments, after the bottom card 410 is bent along the first folding part 415, the sample solution receiving end of the immunochromatographic test strip 200 disposed in the biochemical test strip slot 411 extends to a length of more than 0.5mm outside the biochemical test strip slot 411.

In some embodiments, the immunochromatographic test strip 200 disposed in the biochemical test strip slot 411 is provided with a cavity at the outer end of the intersection point of the first folding part 415 and the immunochromatographic test strip 200, so as to prevent the immunochromatographic test strip 200 from being folded when the bottom card 410 is folded.

In some of these embodiments, the ratio of the height of the cavity to the length of the outer end of the immunochromatographic test strip 200 is greater than 70%.

Example 17

This embodiment is a modification of embodiment 16, and as shown in fig. 48 to 49, a strip cartridge 400 includes a bottom card 410, a first sealing member 420, and a second sealing member 430. The first sealing member 420 covers a first end surface of the bottom card 410, the second sealing member 430 covers a second end surface of the bottom card 410, and the first sealing member 420 and the second sealing member 430 are used to keep the biochemical test paper in the bottom card 410 in a sealed space, so as to keep the biochemical test paper dry.

The structure and connection relationship of the first sealing part 420 and the second sealing part 430 are substantially the same as those of embodiment 16, and are not described herein again.

As shown in FIGS. 50 to 53, the base card 410 includes a biochemical test paper slot 411, a first sealing surface 412, a sample solution adding hole 413, a second sealing surface 414, and a first folding member 415.

The first sealing surface 412, the sample solution addition hole 413, the second sealing surface 414, and the first folding member 415 have substantially the same structure and connection relationship as those of embodiment 16, and are not described herein again.

The two biochemical test paper slots 411 are arranged in parallel, and the two biochemical test paper slots 411 are spaced apart from each other, so that the immunochromatographic test paper 200 respectively positioned in the two biochemical test paper slots 411 do not contact each other. The two biochemical test paper slots 411 are respectively communicated with the sample solution adding holes 413.

In some embodiments, the number of the biochemical test paper slots 411 may be more than two.

In this embodiment, two biochemical test paper tanks 411 are provided to allow different test items to be simultaneously performed.

Example 18

This embodiment is a modification of embodiment 17, and as shown in fig. 54, a strip cassette 400 includes a bottom card 410, a first sealing member 420, and a second sealing member 430. The first sealing member 420 covers a first end surface of the bottom card 410, the second sealing member 430 covers a second end surface of the bottom card 410, and the first sealing member 420 and the second sealing member 430 are used to keep the biochemical test paper in the bottom card 410 in a sealed space, so as to keep the biochemical test paper dry.

The structure and connection relationship of the first sealing part 420 and the second sealing part 430 are substantially the same as those of embodiment 17, and are not described herein again.

As shown in FIGS. 55 to 57, the base card 410 includes a biochemical test paper slot 411, a first sealing surface 412, a sample solution addition hole 413, a second sealing surface 414, a first folding member 415, and a second folding member 416.

The structure and connection relationship of the biochemical test paper slot 411, the first sealing surface 412, the sample solution adding hole 413, the second sealing surface 414, and the first folding component 415 are substantially the same as those in embodiment 17, and are not described herein again.

The second folding member 416 is disposed on the first end surface of the bottom card 410, is located inside the biochemical test paper slot 411, and corresponds to the first folding member 415, so as to rapidly fold the bottom card 410.

In some of these embodiments, the second fold features 416 are transverse folds.

Example 19

This embodiment is a modification of embodiment 18, and as shown in fig. 58 to 60, a strip cartridge 400 includes a bottom card 410, a first sealing member 420, a second sealing member 430, and a sliding member 440. The first sealing member 420 covers a first end face of the bottom card 410, the second sealing member 430 covers a second end face of the bottom card 410, and the first sealing member 420 and the second sealing member 430 are used for keeping the biochemical test paper arranged in the bottom card 410 in a closed space, so as to keep dry; the sliding member 440 is slidably disposed on the bottom card 410 for closing the bottom card 410 under certain conditions.

The structure and connection relationship of the first sealing part 420 and the second sealing part 430 are substantially the same as those of embodiment 18, and are not described herein again.

The base card 410 includes a biochemical test paper slot 411, a first sealing surface 412, a sample solution adding hole 413, a second sealing surface 414, a first folding member 415, a second folding member 416, a slide member 417, and an anti-slip member 418.

The structure and connection relationship of the biochemical test paper slot 411, the first sealing surface 412, the sample solution adding hole 413, the second sealing surface 414, the first folding component 415, and the second folding component 416 are substantially the same as those in embodiment 18, and are not described herein again.

The slide rail members 417 are symmetrically disposed at left and right sides of the bottom card 410, and are configured to be slidably coupled to the slide member 440, such that the slide member 440 performs a reciprocating motion along the slide rail members 417.

Wherein the slide member 417 is disposed across the first fold member 415. Specifically, after the bottom card 410 is bent at the first folding part 415, the bottom card 410 is divided into a first portion and a second portion, the first portion of the bottom card 410 is not separated from the second portion of the bottom card 410, and the first portion of the bottom card 410 is bent from the second portion of the bottom card 410; both the left and right sides of the first portion of the bottom card 410 are provided with slide rail members 417, and both the left and right sides of the second portion of the bottom card 410 are also provided with slide rail members 417, at this time, the slide member 440 is located at the first portion of the bottom card 410; after the second portion of the bottom card 410 is reset, the second portion of the bottom card 410 and the first portion of the bottom card 410 are in a horizontal state, and at this time, the sliding member 440 slides along the rail member 417, one portion of the sliding member 440 is slidably connected to the rail member 417 of the first portion of the bottom card 410, and the other portion of the sliding member 440 is slidably connected to the rail member 417 of the second portion of the bottom card 410, and shields the sample solution addition hole 413, thereby sealing the bottom card 410.

Wherein the first end of the sliding rail member 417 is located at the first end of the bottom card 410 (i.e., near the sample solution adding hole 413), and the second end of the sliding rail member 417 is located at the middle position of the bottom card 410, so as to reduce the sliding distance of the sliding member 440.

The anti-slip members 418 are provided at both ends of the slide rail member 417 to prevent the slide member 440 from slipping off.

In some embodiments, the anti-slip feature 418 is a limit stop or a limit protrusion.

The method of use of this example is as follows: bending the bottom card 410 at the positions of the first folding part 415 and the second folding part 416 to form a first portion and a second portion to expose the immunochromatographic test strip 200 previously disposed in the biochemical test strip slot 411 of the bottom card 410, and contacting a sample solution receiving end of the immunochromatographic test strip 200 with a sample solution; then, the second portion of the bottom card 410 is reset, so that the bottom card 410 is again in a horizontal state, the sliding member 440 slides along the sliding rail member 417, and a portion of the sliding member 440 is slidably connected to the sliding rail member 417 of the first portion of the bottom card 410, and another portion of the sliding member 440 is slidably connected to the sliding rail member 417 of the second portion of the bottom card 410, and the sample solution adding hole 413 is shielded, so as to seal the bottom card 410, thereby forming a short-time sealed state, and preventing external moisture from contacting the immunochromatographic test strip 200.

While the invention has been described with reference to a preferred embodiment, it will be understood by those skilled in the art that various changes in form and detail may be made therein without departing from the spirit and scope of the invention.

Claims

1. The biochemical test paper tube is characterized by comprising a tube part and a cover part, wherein the cover part is matched with the tube part in an interpolation way;

the tube portion includes:

a solution chamber;

the test paper fixing part extends from the bottom end of the inner wall of the cover part on the top of the sample receiving end of the test paper or biochemical test paper positioned in the test paper fixing part under the condition that the cover part seals the tube part, the vertical interval between the test paper fixing part and the top of the cover part is less than 2mm, and the horizontal interval between the outer edge of the test paper fixing part and the inner wall of the tube opening of the tube part is greater than the wall thickness of the inserted tube opening of the cover part;

2. The biochemical test paper tube according to claim 1, wherein the width of the test paper fixing member is not more than 2.8mm, and the depth of the test paper fixing member is not less than 28 mm.

3. The biochemical test paper tube according to claim 1, wherein the cover portion comprises:

a cavity formed by an inner surface of the cover portion bulging outward;

4. The biochemical test paper tube according to claim 1, further comprising an opening prevention member;

the cover portion includes:

a stopper member provided on an outer wall of the lid portion;

5. The biochemical test paper tube according to claim 4, wherein the opening prevention member includes a counter bore provided at a top of the tube opening of the tube portion.

6. The biochemical test paper tube according to claim 4 or 5, wherein the opening prevention member includes a chamfered portion provided on an outer wall of the stopper member;

7. The biochemical test paper tube according to claim 5, wherein the opening prevention member further comprises:

8. The biochemical test paper tube according to claim 1, wherein the cover portion further comprises:

a sealing member provided on an outer wall of the lid section;

the tube portion includes:

9. The biochemical test paper tube according to claim 1, further comprising:

10. The biochemical test paper tube according to claim 1, further comprising:

the biochemical test paper is arranged inside the test paper fixing part;

11. The biochemical test paper tube according to claim 10, wherein the biochemical test paper is disposed to protrude from the test paper fixing member.

12. The biochemical test strip cartridge of claim 10, wherein the biochemical test strip is an immunochromatographic test strip comprising:

a substrate;

a chromatographic membrane disposed on an upper surface of the substrate;

the water absorption pad is arranged on the lower surface of the base material;

13. The biochemical test paper tube according to claim 12, wherein the end of the chromatographic membrane is beyond the end of the substrate by a certain distance, the end of the absorbent pad is beyond the end of the substrate by a certain distance, and the end of the chromatographic membrane is in contact with the end of the absorbent pad and performs solution transfer; or

The chromatographic membrane is also arranged on the lower surface of the substrate, and the tail end of the chromatographic membrane and the tail end of the water absorption pad are contacted on the lower surface of the substrate and carry out solution transmission; or

The water absorption pad is further arranged on the upper surface of the base material, and the tail end of the chromatographic membrane and the tail end of the water absorption pad are in contact with each other on the upper surface of the base material and are used for solution transmission.

14. The biochemical test strip cartridge of claim 12, wherein the immunochromatographic test strip further comprises:

15. The biochemical test paper tube according to claim 10, further comprising:

16. The biochemical test paper tube according to claim 15, wherein one end of the transparent hollow tube is a closed end.

17. The biochemical test paper tube according to claim 1, wherein the test paper fixing member is a test paper cartridge including:

a base card, the base card comprising:

18. The biochemical test paper tube of claim 17, wherein the base card further comprises:

a second sealing surface disposed around the sample solution addition hole;

the test strip card box still includes:

19. The biochemical test paper tube of claim 18, wherein the base card further comprises:

20. The biochemical test paper tube according to claim 19, wherein after the bottom card is bent along the first folding part, a length of a sample solution receiving end of a biochemical test paper strip arranged in the biochemical test paper slot extending outside the biochemical test paper slot is greater than 0.5 mm.

21. The biochemical test paper tube of claim 19, wherein the first folding member comprises:

22. The biochemical test paper tube according to claim 19, wherein a cavity is provided at an outer end of the biochemical test paper strip of the biochemical test paper slot at an intersection of the first fold part and the biochemical test paper strip, and a ratio of a height of the cavity to a length of the outer end of the biochemical test paper strip is greater than 70%.

23. The biochemical test paper tube according to claim 18, wherein the bottom card is made of a transparent material; and/or

24. The biochemical test paper tube of claim 19, wherein the base card further comprises:

the test strip card box still includes:

25. The biochemical test paper tube of claim 24, wherein the base card further comprises: