CN214845315U - Antigen detection kit based on quantum dot quantification - Google Patents
Antigen detection kit based on quantum dot quantification Download PDFInfo
- Publication number
- CN214845315U CN214845315U CN202121105058.4U CN202121105058U CN214845315U CN 214845315 U CN214845315 U CN 214845315U CN 202121105058 U CN202121105058 U CN 202121105058U CN 214845315 U CN214845315 U CN 214845315U
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- China
- Prior art keywords
- test paper
- quantum dot
- antigen detection
- groove
- detection kit
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- Expired - Fee Related
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- 238000001514 detection method Methods 0.000 title claims abstract description 23
- 102000036639 antigens Human genes 0.000 title claims abstract description 22
- 108091007433 antigens Proteins 0.000 title claims abstract description 22
- 239000002096 quantum dot Substances 0.000 title claims abstract description 22
- 239000000427 antigen Substances 0.000 title claims abstract description 21
- 238000011002 quantification Methods 0.000 title claims abstract description 11
- 238000012360 testing method Methods 0.000 claims abstract description 85
- 238000007789 sealing Methods 0.000 claims abstract description 37
- 239000000872 buffer Substances 0.000 claims abstract description 17
- 229920000742 Cotton Polymers 0.000 claims abstract description 9
- 239000000020 Nitrocellulose Substances 0.000 claims description 10
- 239000012528 membrane Substances 0.000 claims description 10
- 229920001220 nitrocellulos Polymers 0.000 claims description 10
- 238000010521 absorption reaction Methods 0.000 claims description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 3
- 239000007788 liquid Substances 0.000 abstract description 10
- 239000007853 buffer solution Substances 0.000 description 8
- 241000700605 Viruses Species 0.000 description 5
- 239000003153 chemical reaction reagent Substances 0.000 description 5
- 238000005070 sampling Methods 0.000 description 3
- 206010011409 Cross infection Diseases 0.000 description 2
- 206010029803 Nosocomial infection Diseases 0.000 description 2
- 239000012141 concentrate Substances 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000003760 hair shine Effects 0.000 description 2
- 238000003018 immunoassay Methods 0.000 description 2
- 238000011179 visual inspection Methods 0.000 description 2
- 241000283707 Capra Species 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 239000000090 biomarker Substances 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 238000003317 immunochromatography Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000004005 microsphere Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000001989 nasopharynx Anatomy 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
Images
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- Investigating Or Analysing Biological Materials (AREA)
Abstract
The utility model relates to the technical field of medical detection test paper, in particular to an antigen detection kit based on quantum dot quantification, which comprises a box body, a test paper placing cavity is formed on the box body, a test paper component is arranged on a positioning frame in the test paper placing cavity, one side of the test paper placing cavity is provided with a buffer liquid hole, a buffer liquid bottle is placed in the buffer liquid hole, a dropper cover is arranged on the buffer liquid bottle, one side of the buffer liquid hole is respectively provided with a cotton swab groove and a dissolving tube groove, a transparent sealing cover is arranged above the test paper placing cavity, an ultraviolet lampshade is arranged on the inner wall of the test paper placing cavity close to one side of the dissolving tube groove, at least three ultraviolet photodiodes are arranged in the ultraviolet lampshade, and one side of the dissolving tube groove close to the test paper placing cavity is provided with a button for switching the ultraviolet photodiodes; the kit can shield the test paper assembly to prevent the influence on the detection result, and the kit is provided with ultraviolet light to facilitate the observation of the result.
Description
Technical Field
The utility model belongs to the technical field of medical science is with test paper technique and specifically relates to, especially, based on quantitative antigen detect reagent box of quantum dot.
Background
The most effective way to detect viruses is to perform immunoassays, wherein immunoassays comprise detection of nucleic acid segments, specific proteins or antibodies of viruses, and the like. The virus is mainly spread through droplets or contact, the spreading performance is strong, when the kit is adopted for detection, the detection result is inaccurate due to the waiting time required by the kit detection, and if droplets fall into the kit, a plurality of chromatography test paper need to be placed in the same environment for observation by adopting fluorescence immunochromatography, so that the accuracy is also influenced.
SUMMERY OF THE UTILITY MODEL
In order to overcome the defect that prior art exists, the utility model provides a: the utility model provides an antigen detect reagent box based on quantum dot ration, this reagent box can shelter from the test paper subassembly, prevents to influence the testing result, and this reagent box is from taking the ultraviolet light moreover, makes things convenient for the observation result.
The utility model provides a technical scheme that its technical problem adopted is: the utility model provides an antigen detect reagent box based on quantum dot ration, includes the box body, it places the chamber to have seted up the test paper on the box body, the test paper is placed intracavity locating rack and is equipped with the test paper subassembly, the test paper is placed chamber one side and is equipped with the buffer solution hole, the downthehole buffer solution bottle of having placed of buffer solution, be equipped with the burette lid on the buffer solution bottle, buffer solution hole one side is equipped with cotton swab groove and dissolving tube groove respectively, the test paper is placed the chamber top and is equipped with transparent closing cap, the test paper is placed the chamber and is close to be equipped with ultraviolet lampshade on the inner wall of dissolving tube groove one side, be equipped with three at least ultraviolet photodiode in the ultraviolet lampshade, dissolving tube groove is close to one side that the test paper placed the chamber and is equipped with the button that is used for switching ultraviolet photodiode.
Furthermore, a rotating hole is formed in the side face, close to the transparent sealing cover, of the test paper placing cavity, rotating rods corresponding to the rotating hole are arranged on two sides of the lower end of the transparent sealing cover, and a cover uncovering groove is formed in one side, far away from the transparent sealing cover, of the upper portion of the test paper placing cavity.
Furthermore, the test paper placing cavity is provided with two raised positioning blocks, and the positioning blocks are provided with positioning grooves.
Furthermore, positioning columns corresponding to the positioning grooves are arranged at two ends of the lower portion of the test paper assembly.
Furthermore, a sample dropping port is arranged on the test paper assembly, a sealing assembly is arranged on the inner side above the sample dropping port, a display window is arranged on one side of the sample dropping port, and a quantum dot antigen detection test paper group is arranged in the test paper assembly.
Further, the seal assembly is including setting up at the inboard shrouding passageway in dripping appearance mouth top and shrouding groove, wears to be equipped with the shrouding that is used for sealed dripping appearance mouth in this shrouding passageway, and the one end that drips appearance mouth is kept away from to this shrouding is equipped with vertical handle board, and this shrouding groove is corresponding with the shrouding passageway.
Furthermore, quantum dot antigen detects test paper group is including setting up the sample absorption paper in the drop appearance mouth below, and this sample absorption paper is equipped with the combination paper near the below of display window one end, and the below that this combination paper is close to display window one end is equipped with the nitrocellulose membrane, is equipped with T line and C line on this nitrocellulose membrane respectively, and this nitrocellulose membrane other end top lid is equipped with the paper that absorbs water.
Furthermore, a battery cavity is arranged below the button, a circuit board and a wire groove are arranged between the battery cavity and the button, and the circuit board is respectively connected with a battery, the button and an ultraviolet photodiode in the battery cavity through wires.
The utility model has the advantages that: the utility model discloses a test paper subassembly can fix a position and place the intracavity at the test paper, places the ultraviolet photodiode that sets up on the intracavity wall through the test paper and shines the test paper subassembly for visual inspection result does not need to take ultraviolet source in addition, convenient to use, moreover the test paper is placed the chamber top and is equipped with transparent closing cap, places the test paper with the test paper subassembly and places the chamber after, can cover transparent closing cap, and whole kit can concentrate and place and wait for the result together, prevents that the test paper subassembly from appearing the polluted condition, and transparent closing cap can make things convenient for the observation result moreover, does not need to take out the test paper subassembly once more, prevents cross infection.
Drawings
Fig. 1 is a schematic structural diagram of the present invention.
Fig. 2 is a schematic side view of the present invention.
FIG. 3 is a schematic diagram of the test strip assembly.
In the figure: the test paper testing box comprises a box body 1, a test paper placing cavity 2, a buffer liquid hole 3, a cotton swab groove 4, a dissolving tube groove 5, a transparent sealing cover 7, a rotary hole 8, a rotary rod 9, a cover uncovering groove 10, a positioning block 11, a test paper component 12, a positioning column 13, a buffer liquid bottle 14, a dropper cover 15, a sample dropping port 16, a display window 17, a sealing plate channel 18, a sealing plate 19, a handle plate 20, a button 21, a positioning groove 22, an ultraviolet lampshade 23, an ultraviolet photodiode 24, a battery cavity 25, a circuit board 26, a wire groove 27, a sealing plate groove 28, sample absorbing paper 29, bonding paper 30, a nitrocellulose membrane 31, a T line 32, a C line 33 and water absorbing paper 34.
Detailed Description
The following describes the present invention with reference to the accompanying drawings. It should be noted that the description of the embodiments is provided to help understanding of the present invention, but the present invention is not limited thereto. In addition, the technical features related to the embodiments of the present invention described below may be combined with each other as long as they do not conflict with each other.
The antigen detection kit based on quantum dot quantification shown in fig. 1 to 3 comprises a box body 1, wherein a test paper placing cavity 2 is formed in the box body 1, a test paper component 12 is positioned and erected in the test paper placing cavity 2, a buffer hole 3 is formed in one side of the test paper placing cavity 2, a buffer liquid bottle 14 is placed in the buffer hole 3, a dropper cover 15 is arranged on the buffer liquid bottle 14, a cotton swab groove 4 and a dissolving tube groove 5 are respectively formed in one side of the buffer liquid hole 3, a transparent sealing cover 7 is arranged above the test paper placing cavity 2, an ultraviolet lampshade 23 is arranged on the inner wall of the test paper placing cavity 2 close to one side of the dissolving tube groove 5, at least three ultraviolet photodiodes 24 are arranged in the ultraviolet lampshade 23, and a button 21 for switching on and off the ultraviolet photodiodes 24 is arranged on one side of the dissolving tube groove 5 close to the test paper placing cavity 2; the utility model discloses a test paper subassembly 12 can fix a position and place the intracavity 2 at the test paper, places the ultraviolet photodiode 24 that sets up on the 2 inner walls in chamber through the test paper and shines test paper subassembly 12 for visual inspection result does not need to take ultraviolet source in addition, convenient to use, moreover the test paper is placed 2 tops in chamber and is equipped with transparent closing cap 7, places test paper subassembly 12 and places the test paper and place 2 backs in chamber, can cover transparent closing cap 7, and whole kit can concentrate and place and wait for the result together, prevents that the pollution condition from appearing in test paper subassembly 12, and transparent closing cap 7 can conveniently observe the result, need not take out test paper subassembly 12 once more, prevents cross infection.
The test paper placing cavity 2 is provided with a rotating hole 8 on the side face close to the transparent sealing cover 7, rotating rods 9 corresponding to the rotating hole 8 are arranged on two sides of the lower end of the transparent sealing cover 7, a cover opening groove 10 is formed in one side, far away from the transparent sealing cover 7, of the upper portion of the test paper placing cavity 2, and the transparent sealing cover 7 can be opened conveniently through the cover opening groove 10.
The test paper placing cavity 2 is internally provided with two raised positioning blocks 11, the positioning grooves 22 are formed in the positioning blocks 11, and the positioning columns 13 corresponding to the positioning grooves 22 are arranged at two ends of the lower portion of the test paper component 12, so that the test paper component 12 can be conveniently placed in the test paper placing cavity 2, the display window 17 corresponds to the ultraviolet lampshade 23, and the display window 17 can be conveniently irradiated through the ultraviolet photodiode 24 to develop color.
A sample dropping hole 16 is formed in the test paper assembly 12, a sealing assembly is arranged on the inner side above the sample dropping hole 16, a display window 17 is arranged on one side of the sample dropping hole 16, a quantum dot antigen detection test paper group is arranged in the test paper assembly 12, the sealing assembly comprises a sealing plate channel 18 and a sealing plate groove 28 which are arranged on the inner side above the sample dropping hole 16, a sealing plate 19 for sealing the sample dropping hole 16 penetrates through the sealing plate channel 18, a vertical handle plate 20 is arranged at one end, away from the sample dropping hole 16, of the sealing plate 19, and the sealing plate groove 28 corresponds to the sealing plate channel 18; the drip port 16 is sealed by pushing the closure plate 19 through the closure plate channel 18 until the closure plate 19 is inserted into the closure plate slot 28.
The quantum dot antigen detection test paper group comprises sample absorption paper 29 arranged below a sample dropping port 16, binding paper 30 is arranged below one end, close to a display window 17, of the sample absorption paper 29, a nitrocellulose membrane 31 is arranged below one end, close to the display window 17, of the binding paper 30, a T line 32 and a C line 33 are respectively arranged on the nitrocellulose membrane 31, and absorbent paper 34 is covered above the other end of the nitrocellulose membrane 31.
It should be noted that the binding paper 30 is coated with a virus antigen protein or a virus antibody labeled with quantum dot microspheres, a biomarker capable of specifically binding with a target object to be detected is disposed at the T-line 32, and a goat anti-chicken IgY polyclonal antibody is coated on the C-line 33, which are the prior art and are not described in detail.
A battery cavity 25 is arranged below the button 21, a circuit board 26 and a wire casing 27 are arranged between the battery cavity 25 and the button 21, and the circuit board 26 is respectively connected with a battery in the battery cavity 25, the button 21 and the ultraviolet photodiode 24 through wires.
It should be noted that the control circuit among the circuit board 26, the battery, the button 21 and the ultraviolet photodiode 24 is prior art and is not described in detail.
The utility model discloses during the use, earlier use the cotton swab in cotton swab groove 4 to carry out the nasopharynx sampling, then dip into the part of cotton swab sampling and drip in the dissolving tube that has the buffer solution, dissolve tub sampling flexible glue pipe, press the rotatory cotton swab of immersion fluid part simultaneously with the hand, make the sample fully dissolve in the buffer solution, then will dissolve the buffer solution of sample and instil into in dripping appearance mouth 16, seal shrouding 19, place test paper with test paper subassembly 12 and place the chamber 2 in, close transparent closing cap 7, until the time is enough after, open button 21, the visual T line 32 in the display window 17 and the colour development condition of C line 33 can.
The embodiments of the present invention have been described in detail with reference to the accompanying drawings, but the present invention is not limited to the described embodiments. It will be apparent to those skilled in the art that various changes, modifications, substitutions and alterations can be made in the embodiments without departing from the principles and spirit of the invention, and the scope of the invention is to be accorded the full scope of the claims.
Claims (8)
1. Antigen detection kit based on quantum dot ration, including box body (1), its characterized in that, it places chamber (2) to have seted up the test paper on box body (1), the test paper is placed chamber (2) interior location and is erect test paper subassembly (12), the test paper is placed chamber (2) one side and is equipped with buffer hole (3), buffer bottle (14) have been placed in buffer hole (3), be equipped with drip tube lid (15) on buffer bottle (14), buffer hole (3) one side is equipped with cotton swab groove (4) and dissolving tube groove (5) respectively, the test paper is placed chamber (2) top and is equipped with transparent closing cap (7), the test paper is placed and is equipped with ultraviolet lampshade (23) on the inner wall that chamber (2) are close to dissolving tube groove (5) one side, be equipped with three at least ultraviolet photodiode (24) in ultraviolet lampshade (23), dissolving tube groove (5) are close to one side that the test paper was placed chamber (2) and are equipped with and are used for switching ultraviolet photodiode (24) A push button (21).
2. The antigen detection kit based on quantum dot quantification as claimed in claim 1, wherein a rotary hole (8) is formed in the side surface of the test paper placing cavity (2) close to the transparent sealing cover (7), rotary rods (9) corresponding to the rotary holes (8) are arranged on two sides of the lower end of the transparent sealing cover (7), and a cover uncovering groove (10) is formed in one side, far away from the transparent sealing cover (7), above the test paper placing cavity (2).
3. The antigen detection kit based on quantum dot quantification as claimed in claim 1, wherein two raised positioning blocks (11) are arranged in the test paper placing cavity (2), and positioning grooves (22) are formed in the positioning blocks (11).
4. The antigen detection kit based on quantum dot quantification as claimed in claim 1, wherein positioning posts (13) corresponding to the positioning grooves (22) are disposed at two ends below the test paper assembly (12).
5. The antigen detection kit based on quantum dot quantification as claimed in claim 4, wherein a sample dropping port (16) is formed in the test paper assembly (12), a sealing assembly is arranged on the inner side above the sample dropping port (16), a display window (17) is formed on one side of the sample dropping port (16), and a quantum dot antigen detection test paper group is arranged in the test paper assembly (12).
6. The antigen detection kit based on quantum dot quantification as claimed in claim 5, wherein the sealing assembly comprises a sealing plate channel (18) and a sealing plate groove (28) which are arranged on the inner side above the sample dropping port (16), a sealing plate (19) for sealing the sample dropping port (16) penetrates through the sealing plate channel (18), a vertical pull handle plate (20) is arranged at one end of the sealing plate (19) far away from the sample dropping port (16), and the sealing plate groove (28) corresponds to the sealing plate channel (18).
7. The antigen detection kit based on quantum dot quantification as claimed in claim 5, wherein the quantum dot antigen detection test paper set comprises a sample absorption paper (29) arranged below the sample dropping port (16), a bonding paper (30) is arranged below one end of the sample absorption paper (29) close to the display window (17), a nitrocellulose membrane (31) is arranged below one end of the bonding paper (30) close to the display window (17), a T line (32) and a C line (33) are respectively arranged on the nitrocellulose membrane (31), and a water absorption paper (34) is covered above the other end of the nitrocellulose membrane (31).
8. The antigen detection kit based on quantum dot quantification as claimed in claim 1, wherein a battery cavity (25) is arranged below the button (21), a circuit board (26) and a wire groove (27) are arranged between the battery cavity (25) and the button (21), and the circuit board (26) is respectively connected with a battery in the battery cavity (25), the button (21) and the ultraviolet photodiode (24) through wires.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121105058.4U CN214845315U (en) | 2021-05-22 | 2021-05-22 | Antigen detection kit based on quantum dot quantification |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121105058.4U CN214845315U (en) | 2021-05-22 | 2021-05-22 | Antigen detection kit based on quantum dot quantification |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN214845315U true CN214845315U (en) | 2021-11-23 |
Family
ID=78776037
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202121105058.4U Expired - Fee Related CN214845315U (en) | 2021-05-22 | 2021-05-22 | Antigen detection kit based on quantum dot quantification |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN214845315U (en) |
-
2021
- 2021-05-22 CN CN202121105058.4U patent/CN214845315U/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20211123 |