CN211179858U - Serum amyloid A chromatography detection card - Google Patents
Serum amyloid A chromatography detection card Download PDFInfo
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- CN211179858U CN211179858U CN201921555066.1U CN201921555066U CN211179858U CN 211179858 U CN211179858 U CN 211179858U CN 201921555066 U CN201921555066 U CN 201921555066U CN 211179858 U CN211179858 U CN 211179858U
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Abstract
The utility model discloses a serum amyloid A chromatography detection card, wherein a chromatography card shell comprises a card shell cover and a card shell bottom; the shell cover of the card shell is provided with a sample adding hole and an observation window in sequence; the bottom of the card shell is sequentially provided with a dilution liquid tank, a chromatography test paper strip position and a drying agent tank. The chromatography detects the card and includes the utility model discloses chromatography card shell and chromatography test paper strip. The utility model discloses chromatography detects the card and has integrateed dilution cistern, drier groove, has solved and has diluted that the rate of portable pollution is big, the reagent card can't place the scheduling problem for a long time in normal wet environment.
Description
Technical Field
The utility model belongs to the field of in vitro diagnosis, in particular to a serum amyloid A chromatography detection card.
Background
With the rapid development of modern technology, automatic detection equipment is widely applied in the medical inspection industry. The automatic detection device can replace most of complex manual operations, has accurate detection results and good consistency, avoids human errors, reduces pollution, and has higher automatic detection speed and higher efficiency.
At present, when an automatic detection device is adopted to detect a serum amyloid A chromatography detection card, the following problems occur: 1. the full-automatic equipment finishes the processes of sampling, diluting and sample adding by equipment, the dilution is finished in a mixing cup, a sampling head is easy to be polluted, the current common method is to use cleaning liquid and deionized water to clean a needle head and the mixing cup among different samples, and if the cleaning is not clean, the last sample is brought into the subsequent operation to influence the detection result. 2. The immunochromatographic test strip needs to be stored in a dry environment, when a full-automatic instrument is adopted for detection, the reagent card is usually put into a detector in batches after an outer package is removed, and if the time of air contact is long, the chromatographic test strip absorbs moisture to influence the detection result.
Disclosure of Invention
In order to solve the problems, a serum amyloid A chromatography detection card is developed, and comprises a chromatography card shell and a serum amyloid A chromatography test strip; the chromatography card shell comprises a card shell cover and a card shell bottom; the shell cover of the card shell is provided with a sample adding hole and an observation window in sequence; the bottom of the card shell is sequentially provided with a dilution liquid tank, a chromatography test strip position and a drying agent tank; the chromatographic test strip comprises a bottom plate, and a sample pad, a combination pad, a reaction membrane and a water absorption pad are sequentially connected on the bottom plate; the reaction membrane is provided with a quality control line C and a detection line T in parallel; the combination pad is sprayed with antiserum amyloid A antibody marked by time-resolved fluorescent microspheres and chicken IgY marked by time-resolved fluorescent microspheres; the quality control line C is coated with goat anti-chicken IgY, and the detection line T is coated with an anti-serum amyloid A antibody.
In the chromatography detection card, the dilution liquid tank on the bottom of the card shell is positioned at one end of the bottom of the card shell, and the drying agent tank on the bottom of the card shell is positioned at any position from the middle part of the bottom of the card shell to the opposite side of the dilution liquid tank.
In the chromatography detection card, 1 to a plurality of baffles can be arranged in the dilution liquid tank.
The inner surface of the shell cover of the card shell is also provided with a fixing hole, an extrusion strip and an extrusion point respectively; the inner surface of the shell bottom of the clamping shell is provided with a fixing column and a fixing strip; the extrusion strips are respectively positioned on two sides of the observation window on the inner surface of the shell cover.
The fixed columns are respectively positioned at the front part, the middle part and the rear part of the inner surface of the shell bottom; the fixing holes are respectively positioned at the front part, the middle part and the rear part of the inner surface of the shell cover; the fixing column corresponds to the fixing hole in position so as to ensure that the fixing hole and the fixing column can be completely embedded.
And two of the extrusion strips and the sample adding hole are positioned on the same side of the observation window, and the other extrusion strip is positioned on the different side of the observation window.
The fixing strips are respectively positioned at two ends of the chromatographic strip position and used for fixing the chromatographic test strip; the inner side surface of the fixing strip is provided with 1 to a plurality of convex points.
The extrusion points and the sample adding holes are respectively positioned at two ends of the observation window, wherein 2 to a plurality of extrusion points are positioned corresponding to the dryer grooves of the shell bottom, and 1 to a plurality of extrusion points are positioned corresponding to the inner sides of the fixed strips of the shell bottom; the bar code district that the cap surface set up, bar code district and application of sample hole are located the both ends of observation window respectively.
According to the chromatography detection card shell, the shell cover and the shell bottom are separated or integrated, one end of the integrated shell cover is connected with one end of the shell bottom, or one side of the shell cover is connected with one side of the shell bottom, so that the shell cover and the shell bottom are well embedded; the connection comprises fixed connection or movable connection.
1 to a plurality of chutes are arranged on one side of the shell cover and one side of the shell bottom, so that the front and back directions of the shell cover are prevented from being reversed when the separated shell cover is embedded with the shell bottom, and the directions of the shell cover and the shell bottom are consistent; if the chromatography detection card adopts a full-automatic instrument for detection, the sliding groove on the side surface of the chromatography detection card can be matched with the clamping column on the reagent card box, so that the chromatography detection card slides on the clamping column, and the phenomenon of inclination and turnover when the chromatography detection card is taken out of the card is prevented.
The chromatography detection card is characterized in that the dilution liquid tank is integrated or detachable.
Above-mentioned chromatography detects the card, still be equipped with on the casing and dismantle sealed lid, sealed lid covers with sample hole, observation window.
The chromatography test strip is positioned at the chromatography strip position at the bottom of the card shell, and two ends of the chromatography test strip are clamped at the inner side of the fixing plate.
The baffle in the dilution liquid tank is integrated or can be moved and detached, so that the chromatography detection card is suitable for detection of special items, such as: 1. the sample is treated by two or more diluents and then detected; 2. the sample needs to be diluted by multiple times before detection.
The diluent in the diluent groove is sealed by a sealing film, and the sealing film comprises an aluminum foil film, a plastic film, a rubber film and the like, preferably the aluminum foil film.
The extrusion points on the shell cover correspond to the chromatography test paper strips and the drying agents on the shell bottom respectively, so that the fixed reagent strips and the drying agents are prevented from being shifted and shaken in the transportation and use processes.
The shell bottom is provided with a chromatography test strip position, and the chromatography test strip is placed on the chromatography test strip position on the shell bottom and is embedded between the fixing strips at the two ends.
Technical effects
1. According to the serum amyloid A chromatography detection card, the dilution liquid tank is connected to the chromatography card shell, the dilution and sample adding processes are carried out in the dilution liquid tank on the chromatography detection card, and each chromatography card is provided with one dilution liquid tank, so that the influence on the detection result caused by the fact that a previous sample is brought into the subsequent operation due to incomplete cleaning is avoided, and the probability of wrong adding of the dilution liquid can be effectively reduced; in addition, the chromatography card shell is connected with a diluent tank, and a diluent container does not need to be additionally equipped, so that the production cost is reduced.
2. According to the serum amyloid A chromatography detection card, the drying agent groove is formed in the bottom of the shell, when the chromatography detection card is assembled, the drying agent is filled into the drying agent groove, and after an outer package of the chromatography detection card is opened, the drying agent is placed in the shell of the card, so that a chromatography test strip can be kept in a dry state for a long time in a normal-humidity environment, the chromatography effect of the chromatography test strip is prevented from being influenced due to moisture absorption, and detection errors are reduced.
Drawings
FIG. 1: is a schematic structural diagram of the outer surface of the shell cover of the chromatography card shell.
FIG. 2: is a schematic structural diagram of the inner surface of the shell cover of the chromatography card shell.
FIG. 3: the structure of the inner surface of the shell bottom of the chromatography card is shown schematically, wherein the diluting fluid tank is integrated.
FIG. 4: the inner surface of the shell cover of the chromatography card shell is in a schematic structure, wherein the diluting fluid groove is detachable.
FIG. 5: is a structural schematic diagram of the connection of the chromatography shell cover and the chromatography shell bottom.
FIG. 6: is a schematic diagram of a chromatographic test strip.
Description of reference numerals: 101-shell cover, 102-shell cover, 201-shell bottom, 202-shell bottom, 6-observation window, 7-sample adding hole, 8-extrusion strip, 9-extrusion point, 10-fixed hole, 11-fixed column, 12-dilution liquid tank, 13-drying agent tank, 14-salient point, 15-fixed strip, 16-sliding chute, 17-chromatography test strip position, 18-bar code area, 21-sample pad, 22-combination pad, 23-coating film, 24-water absorption pad, 25-bottom plate, T-detection area T line and C-quality control area C line.
Detailed Description
The invention will be further described with reference to the following examples.
Example 1
A serum amyloid A chromatography detection card comprises a chromatography card shell and a serum amyloid A chromatography test strip; the chromatography card shell comprises a card shell cover 101 and a card shell bottom 201; the shell cover of the card shell is sequentially provided with a sample adding hole 7 and an observation window 6; the bottom of the card shell is sequentially provided with a dilution liquid tank 12, a chromatography test strip position 17 and a drying agent tank 13; the inner surface of the shell cover is also respectively provided with a fixing hole 10; the inner surface of the shell bottom is provided with a fixed column 11 and a fixed strip 15; the chromatographic test strip comprises a bottom plate, and a sample pad, a combination pad, a reaction membrane and a water absorption pad are sequentially connected on the bottom plate; the reaction membrane is provided with a quality control line C and a detection line T in parallel; the combination pad is sprayed with antiserum amyloid A antibody marked by time-resolved fluorescent microspheres and chicken IgY marked by time-resolved fluorescent microspheres; the quality control line C is coated with goat anti-chicken IgY, and the detection line T is coated with an anti-serum amyloid A antibody.
The diluting liquid tank and the drying agent tank on the bottom of the clamping shell are respectively positioned at two ends of the bottom of the clamping shell; the dilution liquid tank is integrated.
Example 2
A serum amyloid A chromatography detection card comprises a chromatography card shell and a serum amyloid A chromatography test strip; the chromatography card shell comprises a card shell cover 101 and a card shell bottom 201; the shell cover of the card shell is sequentially provided with a sample adding hole 7 and an observation window 6; the bottom of the card shell is sequentially provided with a dilution liquid tank 12, a chromatography test strip position 17 and a drying agent tank 13; the inner surface of the shell cover is also provided with a fixing hole 10, an extrusion strip 8 and an extrusion point 9 respectively; the inner surface of the shell bottom is provided with a fixed column 11 and a fixed strip 15; the chromatographic test strip comprises a bottom plate, and a sample pad, a combination pad, a reaction membrane and a water absorption pad are sequentially connected on the bottom plate; the reaction membrane is provided with a quality control line C and a detection line T in parallel; the combination pad is sprayed with antiserum amyloid A antibody marked by time-resolved fluorescent microspheres and chicken IgY marked by time-resolved fluorescent microspheres; the quality control line C is coated with goat anti-chicken IgY, and the detection line T is coated with an anti-serum amyloid A antibody.
The diluting liquid tank and the drying agent tank on the bottom of the clamping shell are respectively positioned at two ends of the bottom of the clamping shell; the diluting liquid groove is of a separated type.
Example 3
A serum amyloid A chromatography detection card comprises a chromatography card shell and a serum amyloid A chromatography test strip; the chromatography card shell comprises a card shell cover 101 and a card shell bottom 202; the shell cover of the card shell is sequentially provided with a sample adding hole 7 and an observation window 6; the bottom of the card shell is sequentially provided with a dilution liquid tank 12, a chromatography test strip position 17 and a drying agent tank 13; the inner surface of the shell cover is also provided with a fixing hole 10, an extrusion strip 8 and an extrusion point 9 respectively; the inner surface of the shell bottom is provided with a fixed column and a fixed strip; the chromatographic test strip comprises a bottom plate, and a sample pad, a combination pad, a reaction membrane and a water absorption pad are sequentially connected on the bottom plate; the reaction membrane is provided with a quality control line C and a detection line T in parallel; the combination pad is sprayed with antiserum amyloid A antibody marked by time-resolved fluorescent microspheres and chicken IgY marked by time-resolved fluorescent microspheres; the quality control line C is coated with goat anti-chicken IgY, and the detection line T is coated with an anti-serum amyloid A antibody.
The diluting liquid tank and the drying agent tank on the bottom of the clamping shell are respectively positioned at two ends of the bottom of the clamping shell; and 2 sliding grooves are respectively formed in one side of the shell cover and one side of the shell bottom, and the diluting liquid groove is integrated.
Although the present invention has been described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that the present invention can be modified or replaced with other embodiments without departing from the spirit and scope of the present invention.
Claims (9)
1. A serum amyloid A chromatography detection card comprises a chromatography card shell and a serum amyloid A chromatography test strip; the chromatography card shell comprises a card shell cover and a card shell bottom; the shell cover of the card shell is provided with a sample adding hole and an observation window in sequence; it is characterized in that the bottom of the card shell is provided with a dilution liquid tank, a chromatography test paper strip position and a drying agent tank in sequence; the chromatographic test strip comprises a bottom plate, and a sample pad, a combination pad, a reaction membrane and a water absorption pad are sequentially connected on the bottom plate; the reaction membrane is provided with a quality control line C and a detection line T in parallel; the combination pad is sprayed with antiserum amyloid A antibody marked by time-resolved fluorescent microspheres and chicken IgY marked by time-resolved fluorescent microspheres; the quality control line C is coated with goat anti-chicken IgY, and the detection line T is coated with an anti-serum amyloid A antibody.
2. The serum amyloid a chromatographic detection card according to claim 1, wherein: the diluting liquid tank on the bottom of the clamping shell is positioned at one end of the bottom of the clamping shell, and the drying agent tank on the bottom of the clamping shell is positioned at any position from the middle of the bottom of the clamping shell to the opposite side of the diluting liquid tank.
3. The serum amyloid a chromatographic detection card according to claim 1, wherein: the inner surface of the shell cover of the card shell is provided with a fixing hole, an extrusion strip and an extrusion point; and the inner surface of the bottom of the clamping shell is provided with a fixing column and a fixing strip.
4. The serum amyloid a chromatographic detection card according to claim 3, wherein: the fixed columns are respectively positioned at the front part, the middle part and the rear part of the inner surface of the shell bottom; the fixing holes are respectively positioned at the front part, the middle part and the rear part of the inner surface of the shell cover; the fixing column corresponds to the fixing hole in position.
5. The serum amyloid a chromatographic detection card according to claim 3, wherein: the fixing strips are respectively positioned at two ends of the chromatography strip position, and two parallel fixing strips are respectively arranged at the two ends; the inner side surface of the fixing strip is provided with 1 to a plurality of convex points.
6. The serum amyloid a chromatographic detection card according to claim 3, wherein: the extrusion points and the sample adding holes are respectively positioned at two ends of the observation window, wherein 2 to a plurality of extrusion points are positioned corresponding to the dryer grooves of the shell bottom, and 2 to a plurality of extrusion points are positioned corresponding to the inner sides of the fixing strips of the shell bottom; the surface of the shell cover is provided with a bar code area, and the bar code area and the sample adding hole are respectively positioned at two ends of the observation window.
7. The serum amyloid a chromatographic detection card according to claim 1, wherein: the shell cover and the shell bottom are separated or integrated, one end of the integrated shell cover is connected with one end of the shell bottom, or one side of the shell cover is connected with one side of the shell bottom, and the connection comprises fixed connection or movable connection.
8. The serum amyloid a chromatographic test card according to any one of claims 1 to 7, wherein: and 1 to a plurality of sliding grooves are respectively arranged on one side of the shell cover and one side of the shell bottom, wherein the positions of the sliding grooves of the shell cover and the shell bottom correspond to each other.
9. The serum amyloid a chromatographic detection card according to claim 8, wherein: above-mentioned chromatography card shell, the shell is covered and still is equipped with the sealed lid of dismantling, sealed lid covers add kind of hole, observation window.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921555066.1U CN211179858U (en) | 2019-09-06 | 2019-09-06 | Serum amyloid A chromatography detection card |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921555066.1U CN211179858U (en) | 2019-09-06 | 2019-09-06 | Serum amyloid A chromatography detection card |
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| CN211179858U true CN211179858U (en) | 2020-08-04 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201921555066.1U Active CN211179858U (en) | 2019-09-06 | 2019-09-06 | Serum amyloid A chromatography detection card |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112540173A (en) * | 2020-12-02 | 2021-03-23 | 赛莱克斯生物科技(苏州)有限公司 | Sample adding device and auxiliary sample adding type test structure |
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2019
- 2019-09-06 CN CN201921555066.1U patent/CN211179858U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112540173A (en) * | 2020-12-02 | 2021-03-23 | 赛莱克斯生物科技(苏州)有限公司 | Sample adding device and auxiliary sample adding type test structure |
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