CN216646531U - Kit for rapidly evaluating hepatitis A vaccination effect - Google Patents
Kit for rapidly evaluating hepatitis A vaccination effect Download PDFInfo
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- CN216646531U CN216646531U CN202123154141.3U CN202123154141U CN216646531U CN 216646531 U CN216646531 U CN 216646531U CN 202123154141 U CN202123154141 U CN 202123154141U CN 216646531 U CN216646531 U CN 216646531U
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- pad
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- sealing box
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- 230000000694 effects Effects 0.000 title claims abstract description 18
- 208000005252 hepatitis A Diseases 0.000 title claims abstract description 18
- 238000002255 vaccination Methods 0.000 title claims abstract description 18
- 238000001514 detection method Methods 0.000 claims abstract description 38
- 239000003085 diluting agent Substances 0.000 claims abstract description 25
- 239000003550 marker Substances 0.000 claims abstract description 17
- 238000007789 sealing Methods 0.000 claims abstract description 17
- 239000000427 antigen Substances 0.000 claims abstract description 15
- 102000036639 antigens Human genes 0.000 claims abstract description 14
- 108091007433 antigens Proteins 0.000 claims abstract description 14
- 238000003908 quality control method Methods 0.000 claims abstract description 14
- 238000010521 absorption reaction Methods 0.000 claims abstract description 13
- 238000001035 drying Methods 0.000 claims abstract description 10
- 239000011248 coating agent Substances 0.000 claims description 9
- 238000000576 coating method Methods 0.000 claims description 9
- 239000007788 liquid Substances 0.000 claims description 7
- 238000011156 evaluation Methods 0.000 claims description 3
- 238000010790 dilution Methods 0.000 abstract description 4
- 239000012895 dilution Substances 0.000 abstract description 4
- 206010019799 Hepatitis viral Diseases 0.000 description 3
- 229940124724 hepatitis-A vaccine Drugs 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 201000001862 viral hepatitis Diseases 0.000 description 3
- 230000001154 acute effect Effects 0.000 description 2
- POIUWJQBRNEFGX-XAMSXPGMSA-N cathelicidin Chemical compound C([C@@H](C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(O)=O)NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CC(C)C)C1=CC=CC=C1 POIUWJQBRNEFGX-XAMSXPGMSA-N 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 208000006454 hepatitis Diseases 0.000 description 2
- 230000001900 immune effect Effects 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- TVEXGJYMHHTVKP-UHFFFAOYSA-N 6-oxabicyclo[3.2.1]oct-3-en-7-one Chemical compound C1C2C(=O)OC1C=CC2 TVEXGJYMHHTVKP-UHFFFAOYSA-N 0.000 description 1
- 238000002965 ELISA Methods 0.000 description 1
- 206010019842 Hepatomegaly Diseases 0.000 description 1
- 241000709721 Hepatovirus A Species 0.000 description 1
- 206010028813 Nausea Diseases 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 231100000354 acute hepatitis Toxicity 0.000 description 1
- 208000022531 anorexia Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000010241 blood sampling Methods 0.000 description 1
- 206010061428 decreased appetite Diseases 0.000 description 1
- 238000007865 diluting Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 231100000283 hepatitis Toxicity 0.000 description 1
- 230000003908 liver function Effects 0.000 description 1
- 230000008693 nausea Effects 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 201000005404 rubella Diseases 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
Images
Classifications
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Investigating Or Analysing Biological Materials (AREA)
Abstract
The utility model discloses a kit for rapidly evaluating the vaccination effect of hepatitis A, which belongs to the technical field of medical instruments, wherein a tear strip is arranged in the middle of one side of the outer side of an outer sealing box, an observation port is arranged in the middle of one side of the outer wall of the outer sealing box, a diluent storage tank is arranged in one side of the inner part of the outer sealing box, an instruction book is arranged in one side of the diluent storage tank, a drying piece is arranged in one side of the instruction book, a base detection component is arranged in a detection piece main body, a combination pad component is arranged at the bottom of the combination pad component, after the drying piece is taken out, the tear strip on one side of the outer sealing box can be pulled to take out the diluent storage tank, a patient extract is placed in the diluent storage tank for dilution, after dilution is diluted, the diluent is dripped into a dripping port to be mutually contacted with a sample pad, an antigen pad, a marker combination pad and an absorption pad, and quality control C lines and detection T lines in a result display port are used for displaying, so that the kit is convenient to open, can be dried to prolong the effective period, reduce the limitation and facilitate the use and operation.
Description
Technical Field
The utility model relates to a kit for quickly evaluating a vaccination effect, in particular to a kit for quickly evaluating a hepatitis A vaccination effect, and belongs to the technical field of medical instruments.
Background
Viral hepatitis A is acute hepatitis caused by hepatitis A virus, mainly manifested by anorexia, nausea, emesis, debilitation, hepatomegaly and abnormal liver function, the disease is fever at first, clinical experience shows self-limitation, most patients recover to normal in the medical department of the week, in many developing countries, more than 80% of adolescent acute viral hepatitis is hepatitis A virus infection, in developed countries hepatitis A is also relatively common acute viral hepatitis.
The effective measure for preventing the hepatitis A epidemic is to inoculate hepatitis A vaccine, the expanded national immune plan of China has listed the hepatitis A vaccine in a conventional immune program, about ten million children receive the immune vaccination every year, which prompts us that the evaluation of the group immune effect of the hepatitis A vaccine is necessary, the most reliable method for evaluating the immune effect of the vaccine is to detect the content of specific antibodies in serum of an inoculator, the current commercialized kits for detecting rubella antibodies in the market mostly adopt enzyme-linked immunosorbent assay and chemiluminescence methods, although the methods have high flexibility, accurate results and long time consumption, specific devices are also needed, the kits need to be stored at 4 ℃, samples need to be subjected to venous blood sampling and the like, and the popularization and the application in the basic level are difficult.
The existing kit is inconvenient to open, and a drying part is not used for drying the kit, so that the effective period is short, the limitation is high, and therefore a kit for quickly evaluating the hepatitis A vaccination effect is urgently needed, and the problems are solved.
SUMMERY OF THE UTILITY MODEL
The utility model mainly aims to provide a kit for quickly evaluating the hepatitis A vaccination effect, wherein a worker takes out an outer sealing box, pulls a tearing strip on one side of the outer sealing box after taking out the outer sealing box, takes out a diluent storage tank, places a patient extract in the diluent storage tank for dilution, drips the diluent into a dripping liquid port after dilution to be mutually contacted with a sample pad, an antigen pad, a marker combination pad and an absorption pad, and displays the quality control C line and a detection T line in a result display port, so that the kit is convenient to open, can be dried, prolongs the effective period, reduces the limitation, and is convenient to use and operate.
The purpose of the utility model can be achieved by adopting the following technical scheme:
the utility model provides a quick evaluation kit of hepatitis A vaccination effect, including outer seal box, the viewing aperture, the tear strip, detect a main part, the diluent holding vessel, description and dry piece, department is equipped with the tear strip in the middle of the outside one side of outer seal box, the viewing aperture is established in the middle of the outside one side of outer seal box, the inside one side department of outer seal box is placed to the diluent holding vessel, the description is established in diluent holding vessel one side department, dry piece is established in description one side department, detect a main part is established in dry piece one side department, detect a main part, the diluent holding vessel, description and dry piece all place the inside middle department of outer seal box, be equipped with base determine module in the detect a main part, it is equipped with the combination pad subassembly to combine pad subassembly bottom, be equipped with sealed dropping liquid display module in the detect a main part.
Preferably, the base detection assembly comprises a leakage-proof base, a quality control C line and a detection T line, the leakage-proof base is arranged at the bottom in the detection piece main body, the coating film is laid at the top of the leakage-proof base, the detection piece main body is arranged at one side of the middle of the coating film top, and the detection T line is arranged at one side of the quality control C line.
Preferably, the combination pad assembly comprises a sample pad, an antigen pad, a marker combination pad and an absorption pad, wherein the absorption pad is laid at one side of the detection T line, the marker combination pad is laid at one side of the quality control C line, the marker combination pad is connected with the top of the coating film, the antigen pad is laid at one side of the middle of the top of the marker combination pad, and the sample pad is laid at the top of the antigen pad.
Preferably, sealed dropping liquid display module includes drip mouth, result display mouth and top cap, and the top cap is established in detection piece main part top department, and the drip mouth is seted up in the middle of the top cap one side department, and the result display mouth is seted up in drip mouth one side department.
The utility model has the beneficial technical effects that:
according to the kit for quickly evaluating the hepatitis A vaccination effect, provided by the utility model, a worker takes out the outer sealing box, pulls a tearing strip on one side of the outer sealing box after taking out the outer sealing box to pull the diluent storage tank to take out the diluent storage tank, places the extract of a patient in the diluent storage tank to dilute the extract, drips the diluent into the drip opening to be in contact with the sample pad, the antigen pad, the marker combination pad and the absorption pad after diluting, and displays the quality control C line and the detection T line in the result display opening, so that the kit is convenient to open, can be dried, prolongs the effective period, reduces the limitation, and is convenient to use and operate.
Drawings
FIG. 1 is an exploded front view showing the overall three-dimensional structure of a preferred embodiment of a kit for rapidly evaluating the effect of hepatitis A vaccination according to the present invention;
FIG. 2 is a schematic structural diagram of a test paper of a preferred embodiment of the kit for rapidly evaluating the vaccination effect of hepatitis A according to the present invention;
FIG. 3 is a schematic structural diagram of a housing of a kit for rapidly evaluating the effect of hepatitis A vaccination according to a preferred embodiment of the present invention.
In the figure: 1-outer sealed box, 2-observation opening, 3-tearing strip, 4-detection part body, 5-diluent storage tank, 6-instruction book, 7-drying part, 8-dropping opening, 9-result display opening, 10-sample pad, 11-leakproof base, 12-antigen pad, 13-marker combination pad, 14-quality control C line, 15-detection T line, 16-absorption pad, 17-envelope film and 18-top cover.
Detailed Description
In order to make the technical solutions of the present invention more clear and definite for those skilled in the art, the present invention is further described in detail below with reference to the examples and the accompanying drawings, but the embodiments of the present invention are not limited thereto.
As shown in fig. 1-3, the kit for rapidly evaluating the vaccination effect of hepatitis a provided in this embodiment comprises an outer sealing box 1, a viewing port 2, a tear strip 3, a detection member main body 4, diluent holding vessel 5, description 6 and dry piece 7, department is equipped with tear strip 3 in the middle of 1 outside one side of outer seal box, viewing aperture 2 establishes department in the middle of 1 outer wall one side of outer seal box, diluent holding vessel 5 places 1 inside one side department of outer seal box, description 6 establishes jar 5 one side department at diluent holding vessel 5, dry piece 7 establishes 6 one side departments in the description, detect a main part 4 and establish 7 one side departments at dry piece, detect a main part 4, diluent holding vessel 5, description 6 and dry piece 7 all place 1 inside middle department at outer seal box, be equipped with base detection subassembly in detect a main part 4, it is equipped with the bonding pad subassembly to bond pad subassembly bottom, be equipped with sealed dropping liquid display module on detect a main part 4.
The general working principle is as follows: the staff takes out outer seal box 1, can pull open 3 tear strip of 1 one side of outer seal box after taking out and take out dilutent storage tank 5, place the patient extract and dilute in dilutent storage tank 5, dilute after good with dilutent drop income drip 8 in with sample pad 10, antigen pad 12, marker combination pad 13 and absorption pad 16 contact each other, show through the result that matter accuse C line 14 in the 9 shows with detect T line 15, thereby it is convenient for open to reach the kit, can carry out drying process, make its validity period extension, the limitation reduces, convenient to use and operation.
In this embodiment: the base detection assembly comprises a leakage-proof base 11, a quality control C line 14 and a detection T line 15, wherein the leakage-proof base 11 is arranged at the bottom in the detection piece main body 4, a coating film 17 is laid at the top of the leakage-proof base 11, the detection piece main body 4 is arranged at one side of the top middle part of the coating film 17, and the detection T line 15 is arranged at one side of the quality control C line 14.
The local working principle is as follows: leakage prevention, absorption and display are carried out through the leakage-proof base 11, the quality control C line 14, the detection T line 15 and the absorption pad 16.
In this embodiment: the combination pad assembly comprises a sample pad 10, an antigen pad 12, a marker combination pad 13 and an absorption pad 16, wherein the absorption pad 16 is laid at one side of a detection T line 15, the marker combination pad 13 is laid at one side of a quality control C line 14, the marker combination pad 13 is connected with the top of a coating film 17, the antigen pad 12 is laid at one side of the middle of the top of the marker combination pad 13, and the sample pad 10 is laid at the top of the antigen pad 12.
The local working principle is as follows: detection is performed by the sample pad 10, the antigen pad 12, the label binding pad 13, and the absorbent pad 16.
In this embodiment: sealed dropping liquid display module includes drip mouth 8, result display mouth 9 and top cap 18, and top cap 18 is established in 4 tops departments of detection piece main part, and drip mouth 8 is seted up in 18 middle one sides departments of top cap, and result display mouth 9 is seted up in 8 one sides departments of drip mouth.
The local working principle is as follows: dripping and displaying the result are performed through the dripping port 8, the result display port 9 and the top cover 18.
The above are only further embodiments of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art can substitute or change the technical solution of the present invention and its concept within the scope of the present invention.
Claims (4)
1. A hepatitis A vaccination effect rapid evaluation kit, characterized by: comprises an outer sealing box (1), an observation port (2), a tearing strip (3), a detection piece main body (4), a diluent storage tank (5), a specification (6) and a drying piece (7), wherein the tearing strip (3) is arranged in the middle of one side of the outer part of the outer sealing box (1), the observation port (2) is arranged in the middle of one side of the outer wall of the outer sealing box (1), the diluent storage tank (5) is arranged at one side of the inner part of the outer sealing box (1), the specification (6) is arranged at one side of the diluent storage tank (5), the drying piece (7) is arranged at one side of the specification (6), the detection piece main body (4) is arranged at one side of the drying piece (7), the detection piece main body (4), the diluent storage tank (5), the specification (6) and the drying piece (7) are all arranged in the middle of the inner part of the outer sealing box (1), a base detection component is arranged in the detection piece main body (4), a combination pad component is arranged at the bottom of the combination pad component, the detection piece main body (4) is provided with a sealing dropping liquid display component.
2. The kit for rapidly evaluating the vaccination effect of hepatitis A according to claim 1, characterized in that: the base detection assembly comprises a leakage-proof base (11), a quality control C line (14) and a detection T line (15), the leakage-proof base (11) is arranged at the bottom in the detection piece main body (4), the coating film (17) is laid at the top of the leakage-proof base (11), the detection piece main body (4) is arranged at one side of the top middle part of the coating film (17), and the detection T line (15) is arranged at one side of the quality control C line (14).
3. The kit for rapidly evaluating the vaccination effect of hepatitis A according to claim 2, characterized in that: the combined pad assembly comprises a sample pad (10), an antigen pad (12), a marker combined pad (13) and an absorption pad (16), wherein the absorption pad (16) is laid at one side of a detection T line (15), the marker combined pad (13) is laid at one side of a quality control C line (14), the tops of the marker combined pad (13) and a coating film (17) are connected with each other, the antigen pad (12) is laid at one side of the middle of the top of the marker combined pad (13), and the sample pad (10) is laid at the top of the antigen pad (12).
4. The kit for rapidly evaluating the vaccination effect of hepatitis A according to claim 3, characterized in that: sealed dropping liquid display module includes drip mouth (8), result display mouth (9) and top cap (18), and top cap (18) are established in detection piece main part (4) top department, and drip mouth (8) are seted up in top cap (18) middle one side department, and result display mouth (9) are seted up in drip mouth (8) one side department.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202123154141.3U CN216646531U (en) | 2021-12-14 | 2021-12-14 | Kit for rapidly evaluating hepatitis A vaccination effect |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202123154141.3U CN216646531U (en) | 2021-12-14 | 2021-12-14 | Kit for rapidly evaluating hepatitis A vaccination effect |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN216646531U true CN216646531U (en) | 2022-05-31 |
Family
ID=81741653
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202123154141.3U Active CN216646531U (en) | 2021-12-14 | 2021-12-14 | Kit for rapidly evaluating hepatitis A vaccination effect |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN216646531U (en) |
-
2021
- 2021-12-14 CN CN202123154141.3U patent/CN216646531U/en active Active
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| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CP01 | Change in the name or title of a patent holder |
Address after: No. 819, drug City Avenue, Taizhou, Jiangsu Province, Jiangsu Patentee after: Aimei Action Biopharmaceutical Co.,Ltd. Address before: No. 819, drug City Avenue, Taizhou, Jiangsu Province, Jiangsu Patentee before: AIMEI CONVAC BIO-PHARMACY (JIANGSU) Co.,Ltd. |
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| CP01 | Change in the name or title of a patent holder |