CN112704703A

CN112704703A - Traditional Chinese medicine preparation for treating acute proctitis

Info

Publication number: CN112704703A
Application number: CN202110096259.0A
Authority: CN
Inventors: 蓝明见
Original assignee: Individual
Current assignee: Individual
Priority date: 2021-01-25
Filing date: 2021-01-25
Publication date: 2021-04-27

Abstract

The invention discloses a traditional Chinese medicine preparation for treating acute proctitis, which is prepared from the following raw materials: honeysuckle, coptis, scutellaria, forsythia, liquorice, agilawood, rhubarb, phellodendron, gardenia, gentian, plantain, tuckahoe and auxiliary materials. The traditional Chinese medicine preparation disclosed by the invention is reasonable in compatibility, can be used for clearing heat and removing toxicity, increasing the blood circulation of intestinal tracts, relaxing bowel, eliminating the clinical symptoms of acute proctitis, improving the intestinal health on the whole, recovering the normal form and function of intestinal mucosa, effectively improving the treatment effect of the acute proctitis, fundamentally eliminating the pathogeny and preventing the acute proctitis from being recurrent; in addition, the traditional Chinese medicine preparation does not generate any toxic or side effect on a human body in the treatment process of acute proctitis.

Description

Traditional Chinese medicine preparation for treating acute proctitis

Technical Field

The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine preparation for treating acute proctitis.

Background

With the improvement of living standard of people, intestinal diseases are caused by irregular diet work and rest. Proctitis is the most common one, and refers to proctitis diseases caused by various reasons. Proctitis includes acute proctitis and chronic proctitis, wherein the typical symptoms of acute proctitis are hematochezia, anorectal pain and seriously affect the life quality of patients. In the treatment process of acute proctitis, systemic antibiotic therapy is generally adopted for effectively controlling inflammation, but the use of a large amount of antibiotics inherently causes side effects to the body, because antibiotics for treating infection can kill beneficial bacteria in the intestinal tract, so that rectal flora is disordered, although the inflammation of the intestinal mucosa is reduced, the immune system of the body is damaged, and the intestinal health is difficult to recover fundamentally. For acute proctitis with serious symptoms, the patients need to be treated by medical enema and the like, great pain is brought to the patients, and the acute proctitis is easy to relapse and difficult to cure radically.

The traditional Chinese medicine takes the current symptom expression of a patient as a main prescription of reprimation instead of taking the severity of inflammation as a medication reference through dialectical treatment and symptomatic prescription. Traditional Chinese medicine focuses on the holism concept, the human body is a whole body, and the traditional Chinese medicine diagnosis and treatment has the function of self-adjustment, and the traditional Chinese medicine diagnosis and treatment is to use medicines to assist the human body to integrally condition, correct the victory or the failure of yin and yang of viscera, remove pathological factors such as damp heat and the like, and restore the balance of yin and yang of the human body or tend to balance the yin and yang of the human body. Therefore, the traditional Chinese medicine preparation is used for treating acute proctitis, the treatment effect can be effectively improved, the aim of radical treatment is fulfilled, and repeated attack of acute proctitis is prevented.

Disclosure of Invention

The invention aims to solve the problems of great side effect, poor treatment effect and incapability of radical treatment in the prior art of treating acute proctitis by using antibiotics, and provides a traditional Chinese medicine preparation for treating acute proctitis, which can effectively and radically treat acute proctitis and prevent repeated attack.

In order to solve the technical problems, the technical scheme adopted by the invention is as follows: a traditional Chinese medicine preparation for treating acute proctitis is prepared from the following raw materials: honeysuckle, coptis, scutellaria, forsythia, liquorice, agilawood, rhubarb, phellodendron, gardenia, gentian, plantain, tuckahoe and auxiliary materials.

Preferably, the traditional Chinese medicine preparation consists of the following raw materials in parts by weight: 15-25 parts of honeysuckle, 10-20 parts of coptis chinensis, 10-20 parts of scutellaria baicalensis, 10-20 parts of fructus forsythiae, 5-15 parts of liquorice, 10-15 parts of agilawood, 10-20 parts of rheum officinale, 10-20 parts of golden cypress, 15-25 parts of cape jasmine, 15-25 parts of felwort, 10-20 parts of plantain herb, 10-20 parts of poria cocos and 10-20 parts of auxiliary materials.

Preferably, the traditional Chinese medicine preparation consists of the following raw materials in parts by weight: 20 parts of honeysuckle, 15 parts of coptis chinensis, 15 parts of scutellaria baicalensis, 15 parts of fructus forsythiae, 8 parts of liquorice, 12 parts of agilawood, 15 parts of rheum officinale, 15 parts of golden cypress, 20 parts of cape jasmine, 20 parts of gentian, 15 parts of plantain herb, 15 parts of poria cocos and 15 parts of auxiliary materials.

Preferably, the auxiliary material is rice milk or honey.

The Chinese medicinal preparation is prepared from honeysuckle, coptis root, scutellaria root, forsythia, liquorice, agilawood, rhubarb, phellodendron, gardenia, gentian, plantain and poria cocos.

Honeysuckle, sweet and cold; enters lung, heart and stomach meridians, and has the effects of clearing away heat and toxic materials and dispelling wind and heat. The honeysuckle in modern medicine has obvious anti-inflammatory and antipyretic effects.

Coptis root, rhizoma Coptidis has the effects of clearing heat, drying dampness, purging fire and removing toxicity. Rhizoma Coptidis is used for removing damp-heat in spleen, stomach and large intestine, and can be used for treating damp-heat dysentery, abdominal pain and tenesmus.

Baikal skullcap root, bitter and cold in nature, has the effects of clearing heat and drying dampness, purging fire and removing toxicity and stopping bleeding, is good at clearing damp heat in gastrointestinal tract, and can cool blood and stop bleeding.

Fructus forsythiae has effects of clearing away heat and toxic materials, relieving swelling, dispersing pathogen accumulation, and dispelling wind and heat.

The liquorice has sweet taste and neutral nature, enters heart, lung and spleen channels, and has the effects of tonifying qi and strengthening middle warmer, moistening lung to arrest cough, clearing away heat and toxic materials, relieving spasm and pain and harmonizing drug properties.

The agilawood is pungent, bitter and slightly warm in taste, enters spleen, stomach and kidney channels, and has the effects of promoting qi circulation, relieving pain, dredging channels and collaterals and promoting blood circulation.

Rhubarb, radix et rhizoma Rhei entering stomach, large intestine and liver meridians, has the functions of removing dampness and jaundice, clearing heat and relaxing bowels, detoxifying and curing carbuncle.

Phellodendron bark, cortex Phellodendri, bitter and cold in taste, enters kidney and bladder meridians, and has the functions of clearing heat and drying dampness, purging fire and removing steam, detoxifying and treating sore.

Cape jasmine, bitter in taste and cold in nature, enters heart, lung and triple energizer meridians; has effects of purging pathogenic fire, relieving restlessness, clearing heat, promoting diuresis, cooling blood, and removing toxic substance.

Gentian, bitter in taste and cold in nature, enters lung and liver meridians; has effects of clearing heat, eliminating dampness, and purging liver and gallbladder fire.

The plantain herb is sweet in taste and cold in nature, enters liver, kidney and bladder channels, and has the effects of clearing heat, promoting urination, cooling blood and detoxifying.

Poria cocos, sweet and light in flavor, neutral in nature, enters heart, lung, spleen and kidney meridians, and has the effects of inducing diuresis to alleviate edema, excreting dampness, invigorating spleen and calming heart.

The auxiliary materials in the invention are rice milk or honey, and the rice milk has the functions of enriching blood and tonifying qi, and strengthening spleen and stomach; honey has the effects of tonifying middle-jiao and relieving urgency, and moistening intestines and relaxing bowels.

Since acute proctitis is mainly manifested by intestinal mucositis, the mild cases only have intestinal mucositis, and the severe cases have inflammation affecting submucosa, muscularis and even perirectal tissues. Therefore, the elimination of intestinal mucositis and restoration of normal tissue morphology and tissue function of the rectum are the key to treat the disease. According to the invention, the coptis, the scutellaria, the rheum officinale, the golden cypress, the gardenia, the gentian and the plantain are used for compatibility, so that the effects of clearing heat and cooling blood, inducing diuresis and relieving swelling, purging intense heat and removing toxicity are achieved, the damp-heat in the intestinal tract can be effectively removed, and the intestinal inflammation is eliminated; meanwhile, agilawood, honeysuckle, poria cocos, fructus forsythiae and liquorice are added to play roles in promoting qi circulation, relieving pain, promoting intestinal blood circulation, and diminishing swelling and dissipating stagnation. The traditional Chinese medicine composition disclosed by the invention has the effects of clearing away heat and toxic materials, increasing intestinal blood circulation, relaxing bowel and fundamentally recovering normal forms and functions of intestinal mucosa, so that the treatment effect of acute proctitis is effectively improved, and the repeated attack of the acute proctitis is prevented.

The invention has the following beneficial effects: the traditional Chinese medicine preparation disclosed by the invention is reasonable in compatibility, can be used for clearing away heat and toxic materials, increasing the blood circulation of intestinal tracts, relaxing bowel, eliminating the clinical symptoms of acute proctitis, improving the intestinal health on the whole, recovering the normal form and function of intestinal mucosa and effectively improving the treatment effect of acute proctitis; the pathogeny is fundamentally eliminated, and the repeated attack of the acute proctitis is prevented; moreover, the traditional Chinese medicine preparation does not generate any toxic or side effect on a human body in the treatment process of acute proctitis.

Detailed Description

The present invention will be further described with reference to the following examples.

Example 1

Weighing 20 parts of honeysuckle, 15 parts of coptis chinensis, 15 parts of scutellaria baicalensis, 15 parts of fructus forsythiae, 8 parts of liquorice, 12 parts of agilawood, 15 parts of rheum officinale, 15 parts of golden cypress, 20 parts of cape jasmine, 20 parts of gentian, 15 parts of plantain herb and 15 parts of poria cocos. The raw material components are uniformly mixed to obtain a raw material mixture, the raw material mixture is subjected to superfine grinding, 15 parts of rice milk is added, and pills are prepared by adopting a pill making machine.

Example 2

Weighing 15 parts of honeysuckle, 20 parts of coptis chinensis, 10 parts of scutellaria baicalensis, 18 parts of fructus forsythiae, 5 parts of liquorice, 13 parts of agilawood, 20 parts of rheum officinale, 15 parts of golden cypress, 25 parts of cape jasmine, 15 parts of gentian, 15 parts of plantain herb and 20 parts of poria cocos. Decocting the raw material components in water for 1 hour, filtering, collecting liquid medicine, and adding 20 parts of honey to obtain the water preparation.

Example 3

Weighing 25 parts of honeysuckle, 10 parts of coptis chinensis, 20 parts of scutellaria baicalensis, 10 parts of fructus forsythiae, 15 parts of liquorice, 15 parts of agilawood, 15 parts of rheum officinale, 20 parts of golden cypress, 20 parts of cape jasmine, 20 parts of gentian, 20 parts of plantain herb and 15 parts of poria cocos. Decocting the raw material components in water for 1 hour, filtering, collecting liquid medicine, adding 15 parts of honey, and preparing into paste.

Example 4

Weighing 20 parts of honeysuckle, 18 parts of coptis chinensis, 15 parts of scutellaria baicalensis, 20 parts of fructus forsythiae, 12 parts of liquorice, 10 parts of agilawood, 10 parts of rheum officinale, 15 parts of golden cypress, 15 parts of gardenia, 15 parts of gentian, 10 parts of plantain herb and 10 parts of poria cocos. The raw material components are uniformly mixed to obtain a raw material mixture, the raw material mixture is subjected to superfine grinding, 10 parts of rice milk is added, and the micro-pill is prepared by a pill making machine.

Experiment on treatment effect of the invention on acute proctitis

Subject: 200 patients with confirmed acute proctitis. The clinical symptoms of patients with acute proctitis are fever, inappetence, pain in anus, frequent defecation and tenesmus, and congestion of rectal mucosa is found in enteroscopy.

The experimental method comprises the following steps: the pills prepared according to the embodiment 1 are taken three times a day in the morning, in the middle of the day and in the evening, 15 pills are taken each time, and each pill is 1.5 g; the results were observed after 21 consecutive days of administration. Follow-up visit within 6 months after treatment and observation of repeated disease.

The experimental results are as follows: the results are judged according to the treatment criteria, detailed in table 1, as follows:

the effect is shown: the intestinal mucosa is recovered to be normal by enteroscopy, the defecation is recovered to be normal, and the clinical symptoms disappear;

the method has the following advantages: the intestinal mucosa is improved by enteroscopy, and the clinical symptoms are improved;

and (4) invalidation: the intestinal mucosa has no obvious change in enteroscopy, and the clinical symptoms have no obvious change;

side effects: intestinal flora disturbance and low immunity.

TABLE 1 therapeutic Effect of the present invention on acute proctitis

General case (example)	Obvious effect (example)	Effective (example)	Invalid (example)	Side effects (example)	Effective rate (%)
						200	174	23	3	0	98.5％

The treatment data in table 1 show that the traditional Chinese medicine preparation has a very good curative effect on treating acute proctitis, the effective rate reaches over 90%, no side effect is caused to a human body, and no case of acute proctitis recurrence is caused in the follow-up visit of a patient for 6 months after treatment is finished, so that the traditional Chinese medicine preparation can radically treat the acute proctitis and prevent the recurrence.

The application effect of the invention is further illustrated by specific treatment cases, wherein the ointment prepared by the invention in the embodiment 3 is used for 3 times a day, and 20g is taken for each time; a treatment course comprises 21 consecutive days.

Example 1: the patients have the symptoms of the traditional Chinese medicine formula X, male, 25 years old and acute proctitis, and are clinically manifested as low fever, anal pendant and diarrhea. The treatment results are as follows: after taking the medicine for one treatment course, the clinical symptoms completely disappear, and no side effect appears in the treatment course.

Example 2: the patient is plum xxx, female, 41 years old, acute proctitis, and has clinical symptoms of high fever, severe abdominal pain, inappetence and rectal mucosa hyperemia after enteroscopy. The treatment results are as follows: after a course of treatment, the symptoms disappear, the intestinal mucosa is recovered to be normal by enteroscopy, and the patient does not relapse after 6 months of follow-up visit.

As can be shown from the specific treatment cases, the traditional Chinese medicine preparation disclosed by the invention can be used for effectively treating acute proctitis, is good in treatment effect, does not have side effects on a body, and is not easy to relapse after being cured.

The present description is to be considered as illustrative and not restrictive, and it is within the scope of the present invention that certain changes and modifications may be made in the details of the invention without departing from the spirit and scope of the invention.

Claims

1. The traditional Chinese medicine preparation for treating acute proctitis is characterized by comprising the following raw materials: honeysuckle, coptis, scutellaria, forsythia, liquorice, agilawood, rhubarb, phellodendron, gardenia, gentian, plantain, tuckahoe and auxiliary materials.

2. The traditional Chinese medicine preparation according to claim 1, which is prepared from the following raw materials in parts by weight: 15-25 parts of honeysuckle, 10-20 parts of coptis chinensis, 10-20 parts of scutellaria baicalensis, 10-20 parts of fructus forsythiae, 5-15 parts of liquorice, 10-15 parts of agilawood, 10-20 parts of rheum officinale, 10-20 parts of golden cypress, 15-25 parts of cape jasmine, 15-25 parts of felwort, 10-20 parts of plantain herb, 10-20 parts of poria cocos and 10-20 parts of auxiliary materials.

3. The traditional Chinese medicine preparation according to claim 2, which is prepared from the following raw materials in parts by weight: 20 parts of honeysuckle, 15 parts of coptis chinensis, 15 parts of scutellaria baicalensis, 15 parts of fructus forsythiae, 8 parts of liquorice, 12 parts of agilawood, 15 parts of rheum officinale, 15 parts of golden cypress, 20 parts of cape jasmine, 20 parts of gentian, 15 parts of plantain herb, 15 parts of poria cocos and 15 parts of auxiliary materials.

4. The Chinese medicinal preparation according to any one of claims 1 to 3, wherein the adjuvant is rice milk or honey.

5. The traditional Chinese medicine preparation according to any one of claims 1 to 3, wherein the traditional Chinese medicine preparation is one of a pill, a micro-pill, an ointment or an aqua.