CN112704158A - Mixed fermentation type feed additive of traditional Chinese medicine and tea and preparation method thereof - Google Patents

Mixed fermentation type feed additive of traditional Chinese medicine and tea and preparation method thereof Download PDF

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Publication number
CN112704158A
CN112704158A CN202010983741.1A CN202010983741A CN112704158A CN 112704158 A CN112704158 A CN 112704158A CN 202010983741 A CN202010983741 A CN 202010983741A CN 112704158 A CN112704158 A CN 112704158A
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parts
traditional chinese
mixed
chinese medicine
feed additive
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蔡志祥
朱建华
丁小伍
汪洋
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Anhui Zhide Animal Nutrition Technology Co ltd
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Anhui Zhide Animal Nutrition Technology Co ltd
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/30Feeding-stuffs specially adapted for particular animals for swines
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/10Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/12Animal feeding-stuffs obtained by microbiological or biochemical processes by fermentation of natural products, e.g. of vegetable material, animal waste material or biomass
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • A23K10/37Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms from waste material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • A61K36/195Strobilanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315Isatis, e.g. Dyer's woad
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/344Codonopsis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634Forsythia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/78Saururaceae (Lizard's-tail family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P60/00Technologies relating to agriculture, livestock or agroalimentary industries
    • Y02P60/80Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
    • Y02P60/87Re-use of by-products of food processing for fodder production

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Informatics (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Animal Husbandry (AREA)
  • Physiology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Birds (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Sustainable Development (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Fodder In General (AREA)
  • Feed For Specific Animals (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention discloses a mixed fermentation type feed additive of traditional Chinese medicines and tea leaves, which belongs to the field of feed additives and comprises the following raw materials in parts by weight: the traditional Chinese medicine comprises 10-15 parts of dried orange peel, 10-15 parts of honeysuckle, 10-15 parts of fructus forsythiae, 10-15 parts of radix isatidis, 10-15 parts of codonopsis pilosula, 10-15 parts of astragalus membranaceus, 10-15 parts of houttuynia cordata and 10-15 parts of liquorice; tea powder; soybean meal; the mixed strain comprises the main components of 30-40% of bacillus subtilis, 30-40% of lactobacillus and 10-30% of bacillus according to weight ratio. The traditional Chinese medicine and tea mixed feed additive is added into pig feed, after the traditional Chinese medicine and tea mixed feed additive is used, the resistance of pigs can be effectively improved, the morbidity of bacteria and viral diseases is reduced, the mortality of virulent infectious diseases such as African swine fever is reduced, the feed conversion rate is improved, and in addition, the traditional Chinese medicine feed additive added into cattle and sheep feed can also obviously improve the resistance of cattle and sheep and reduce the morbidity.

Description

Mixed fermentation type feed additive of traditional Chinese medicine and tea and preparation method thereof
Technical Field
The invention relates to the field of feed in breeding industry, in particular to a mixed fermentation type feed additive of traditional Chinese medicines and tea leaves and a preparation method thereof.
Background
With the rapid development of social economy and the improvement of the living standard of people, the demand of livestock is more and more large, so that the livestock breeding, such as the breeding of pigs, cattle, sheep and the like, also develops in a large-scale and intensive direction.
With the rapid development of the livestock industry, the problems of antibiotic residue, environmental pollution and the like in food are caused by the long-term mass use of pharmaceutical feed additives, particularly antibiotic additives, and the like, and the wide attention of the whole society is drawn, and the nonreactive culture becomes the future development direction of the breeding industry.
Since the situation of the African swine fever in part of the continental province of 8 months in 2018, the African swine fever causes huge loss to the pig industry, and the prevention and control effects of Chinese herbal medicines are increasingly shown before effective prevention and control means such as specific medicines and African swine fever vaccines are put on the market.
Disclosure of Invention
In order to overcome the defects of the prior art, the invention adopts the mixed fermentation type feed additive of the traditional Chinese medicine and the tea which can improve the resistance of animals, reduce the morbidity and effectively prevent and control the morbidity of African swine fever and the preparation method thereof.
The purpose of the invention is realized by the following scheme: 1. a mixed fermentation type feed additive of traditional Chinese medicines and tea leaves is characterized by comprising the following raw materials in parts by weight: the traditional Chinese medicine comprises 10-15 parts of dried orange peel, 10-15 parts of honeysuckle, 10-15 parts of fructus forsythiae, 10-15 parts of radix isatidis, 10-15 parts of codonopsis pilosula, 10-15 parts of astragalus membranaceus, 10-15 parts of houttuynia cordata and 10-15 parts of liquorice; tea powder; soybean meal; the mixed strain comprises the main components of 30-40% of bacillus subtilis, 30-40% of lactobacillus and 10-30% of bacillus according to weight ratio.
2. The method for preparing the traditional Chinese medicine and tea mixed fermentation type feed additive according to claim 1, wherein the preparation method comprises the following steps:
1) pulverizing folium Camelliae sinensis and Chinese medicinal materials respectively by pulverizer;
2) decocting the Chinese medicinal components to obtain a mixed liquid medicine and a residue mixture;
3) preparing a fermentation mixed solution:
a. stirring by a mixer to prepare a fermentation mixed solution;
b. the preparation method of the mixed strain comprises the following steps of preparing 30-40% of bacillus subtilis, 30-40% of lactobacillus and 10-30% of bacillus according to the weight ratio of main components;
4) mixing and fermenting:
uniformly mixing tea leaves, bean pulp, the traditional Chinese medicine mixture in the step 2) and the fermentation mixed solution in the step 3) through a mixer, adding a proper amount of water to control the water content to be about 45-55%, packaging the mixture into a biological feed packaging bag, and fermenting for 7-10 days at the temperature of 20-45 ℃.
3. The method for preparing a Chinese medicinal feed additive according to claim 1, wherein the Chinese medicinal powder is over 140-180 mesh, and the tea powder is over 40 mesh.
4. The method for preparing a fermentation mixture according to claim 2, wherein the raw materials of the fermentation mixture are mixed with the following strains: glucose and water 4: 625: 2500.
5. the preparation method of the traditional Chinese medicine feed additive according to claim 2, wherein the preparation ratio of the mixed fermentation type feed additive is that the traditional Chinese medicine liquid: tea powder: bean pulp: strain (net weight) 12500: 3000: 2000: 1.
use effect of mixed fermentation type feed additive
Figure RE-GDA0002780971300000031
Results show that after the feed additive is continuously used in a live pig fattening field of a sow propagation field, the fatality rates are respectively 19.7% and 19.0%, and the results are similar and are obviously superior to 36.8% of the results of the traditional antibiotic medicine. The feed can enhance the organism immunity of the pigs, improve the disease resistance of the pigs and play a certain role in preventing and controlling African swine fever.
Finally, it should be noted that: the above embodiments are only used to illustrate the present invention and do not limit the technical solutions described in the present invention; thus, while the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those skilled in the art that various changes may be made and equivalents may be substituted; all such modifications and variations are intended to be included herein within the scope of this disclosure and the present invention and protected by the following claims.

Claims (5)

1. A mixed fermentation type feed additive of traditional Chinese medicines and tea leaves is characterized by comprising the following raw materials in parts by weight: the traditional Chinese medicine comprises 10-15 parts of dried orange peel, 10-15 parts of honeysuckle, 10-15 parts of fructus forsythiae, 10-15 parts of radix isatidis, 10-15 parts of codonopsis pilosula, 10-15 parts of astragalus membranaceus, 10-15 parts of houttuynia cordata and 10-15 parts of liquorice; tea powder; soybean meal; the mixed strain comprises the main components of 30-40% of bacillus subtilis, 30-40% of lactobacillus and 10-30% of bacillus according to weight ratio.
2. The method for preparing the mixed fermentation type feed additive of the traditional Chinese medicine and the tea leaves according to claim 1, wherein the preparation method comprises the following steps:
1) pulverizing folium Camelliae sinensis and Chinese medicinal materials respectively by pulverizer;
2) decocting the Chinese medicinal components to obtain a mixed liquid medicine and a residue mixture;
3) preparing a fermentation mixed solution:
a. stirring by a mixer to prepare a fermentation mixed solution;
b. the preparation of the mixed strain comprises the main components of 30-40% of bacillus subtilis according to the weight ratio,
30-40% of lactobacillus and 10-30% of bacillus;
4) mixing and fermenting:
uniformly mixing tea leaves, bean pulp, the traditional Chinese medicine mixture in the step 2) and the fermentation mixed solution in the step 3) through a mixer, adding a proper amount of water to control the water content to be about 45-55%, packaging the mixture into a biological feed packaging bag, and fermenting for 7-10 days at the temperature of 20-45 ℃.
3. The method for preparing a Chinese medicinal feed additive according to claim 1, wherein the Chinese medicinal powder is over 140-180 mesh, and the tea powder is over 40 mesh.
4. The method for preparing a fermentation mixture according to claim 2, wherein the raw materials of the fermentation mixture are mixed with the following strains: glucose and water 4: 625: 2500.
5. the preparation method of the traditional Chinese medicine feed additive according to claim 2, wherein the preparation ratio of the mixed fermentation type feed additive is that the traditional Chinese medicine liquid: tea powder: bean pulp: strain (net weight) 12500: 3000: 2000: 1.
CN202010983741.1A 2020-09-17 2020-09-17 Mixed fermentation type feed additive of traditional Chinese medicine and tea and preparation method thereof Pending CN112704158A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114404505A (en) * 2022-02-25 2022-04-29 广东温氏大华农生物科技有限公司 South-medicine-based traditional Chinese medicine preparation for preventing and controlling African swine fever and preparation method thereof

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003289814A (en) * 2002-03-29 2003-10-14 Teiu Chikusan Kenkyusho:Kk Feed additive agent for physiological activity increase/ growth and development promotion for cultured marine fish using effective microorganism and chinese herb medicine, and method for producing the same
CN107821822A (en) * 2017-12-01 2018-03-23 无为县雨露生态农业有限公司 Pig cultivation green feed additive
CN109007370A (en) * 2018-08-30 2018-12-18 河南牧业经济学院 Complex function additive for feed for piglets and preparation method thereof
CN109316533A (en) * 2018-12-05 2019-02-12 长沙绿叶生物科技有限公司 It is a kind of remove pig vivotoxin fermented tcm compound preparation and its application
CN111000050A (en) * 2020-01-10 2020-04-14 徐青海 Tea leaf and traditional Chinese medicine mixed feed for growing finishing pigs and preparation method thereof
CN111134233A (en) * 2020-02-26 2020-05-12 河南旭百瑞生物科技股份有限公司 Chinese herbal medicine fermented feed for pigs and production method thereof
CN111587957A (en) * 2020-05-28 2020-08-28 开封嘉骏生物科技有限公司 Functional additive for improving pig conservation capacity and disease resistance and preparation method thereof

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003289814A (en) * 2002-03-29 2003-10-14 Teiu Chikusan Kenkyusho:Kk Feed additive agent for physiological activity increase/ growth and development promotion for cultured marine fish using effective microorganism and chinese herb medicine, and method for producing the same
CN107821822A (en) * 2017-12-01 2018-03-23 无为县雨露生态农业有限公司 Pig cultivation green feed additive
CN109007370A (en) * 2018-08-30 2018-12-18 河南牧业经济学院 Complex function additive for feed for piglets and preparation method thereof
CN109316533A (en) * 2018-12-05 2019-02-12 长沙绿叶生物科技有限公司 It is a kind of remove pig vivotoxin fermented tcm compound preparation and its application
CN111000050A (en) * 2020-01-10 2020-04-14 徐青海 Tea leaf and traditional Chinese medicine mixed feed for growing finishing pigs and preparation method thereof
CN111134233A (en) * 2020-02-26 2020-05-12 河南旭百瑞生物科技股份有限公司 Chinese herbal medicine fermented feed for pigs and production method thereof
CN111587957A (en) * 2020-05-28 2020-08-28 开封嘉骏生物科技有限公司 Functional additive for improving pig conservation capacity and disease resistance and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114404505A (en) * 2022-02-25 2022-04-29 广东温氏大华农生物科技有限公司 South-medicine-based traditional Chinese medicine preparation for preventing and controlling African swine fever and preparation method thereof

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Application publication date: 20210427