CN1126438A - 抗击具无环鸟苷抗性的单纯性疱疹病毒感染的方法 - Google Patents

抗击具无环鸟苷抗性的单纯性疱疹病毒感染的方法 Download PDF

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Publication number
CN1126438A
CN1126438A CN94192662A CN94192662A CN1126438A CN 1126438 A CN1126438 A CN 1126438A CN 94192662 A CN94192662 A CN 94192662A CN 94192662 A CN94192662 A CN 94192662A CN 1126438 A CN1126438 A CN 1126438A
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CN
China
Prior art keywords
ethyl
propyl
methyl
cme
amino carbonyl
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Pending
Application number
CN94192662A
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English (en)
Chinese (zh)
Inventor
詹姆斯·G·查弗里斯
罗伯特·德齐尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bio Mega Boehringer Ingelheim Research Inc
Original Assignee
Bio Mega Boehringer Ingelheim Research Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio Mega Boehringer Ingelheim Research Inc filed Critical Bio Mega Boehringer Ingelheim Research Inc
Publication of CN1126438A publication Critical patent/CN1126438A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN94192662A 1993-05-03 1994-04-29 抗击具无环鸟苷抗性的单纯性疱疹病毒感染的方法 Pending CN1126438A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA002095408A CA2095408A1 (en) 1993-05-03 1993-05-03 Method of combating acyclovir-resistant herpes simplex viral infections
CA2,095,408 1993-05-03

Publications (1)

Publication Number Publication Date
CN1126438A true CN1126438A (zh) 1996-07-10

Family

ID=4151571

Family Applications (1)

Application Number Title Priority Date Filing Date
CN94192662A Pending CN1126438A (zh) 1993-05-03 1994-04-29 抗击具无环鸟苷抗性的单纯性疱疹病毒感染的方法

Country Status (13)

Country Link
EP (1) EP0767671A1 (ko)
JP (1) JPH08509476A (ko)
KR (1) KR960701651A (ko)
CN (1) CN1126438A (ko)
AU (1) AU683465B2 (ko)
BR (1) BR9406575A (ko)
CA (1) CA2095408A1 (ko)
CZ (1) CZ287795A3 (ko)
HU (1) HUT73779A (ko)
NO (1) NO954390L (ko)
SG (1) SG48806A1 (ko)
SK (1) SK132695A3 (ko)
WO (1) WO1994025046A1 (ko)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109627243A (zh) * 2019-01-09 2019-04-16 广西壮族自治区水产科学研究院 一种喷昔洛韦-铜配合物、合成方法及其应用

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5817638A (en) * 1988-07-07 1998-10-06 Nexstar Pharmaceuticals, Inc. Antiviral liponucleosides: treatment of hepatitis B
US6252060B1 (en) 1988-07-07 2001-06-26 Nexstar Pharmaceuticals, Inc. Antiviral liponucleosides: treatment of hepatitis B
US6599887B2 (en) 1988-07-07 2003-07-29 Chimerix, Inc. Methods of treating viral infections using antiviral liponucleotides
CA2139169C (en) * 1994-12-28 2001-05-01 Boehringer Ingelheim (Canada) Ltd./ Boehringer Ingelheim (Canada) Ltee Antiherpes peptidomimetic compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2033448C (en) * 1990-12-31 1996-11-26 Boehringer Ingelheim (Canada) Ltd./ Boehringer Ingelheim (Canada) Ltee Antiherpes compositions and method of use
SG42995A1 (en) * 1992-03-12 1997-10-17 Bio Mega Boehringer Ingelheim Isosteric antiherpes peptide derivatives

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109627243A (zh) * 2019-01-09 2019-04-16 广西壮族自治区水产科学研究院 一种喷昔洛韦-铜配合物、合成方法及其应用
CN109627243B (zh) * 2019-01-09 2021-06-29 广西壮族自治区水产科学研究院 一种喷昔洛韦-铜配合物、合成方法及其应用

Also Published As

Publication number Publication date
CZ287795A3 (en) 1996-06-12
HUT73779A (en) 1996-09-30
CA2095408A1 (en) 1994-11-04
SG48806A1 (en) 1998-05-18
NO954390D0 (no) 1995-11-02
KR960701651A (ko) 1996-03-28
AU6642394A (en) 1994-11-21
WO1994025046A1 (en) 1994-11-10
SK132695A3 (en) 1996-10-02
AU683465B2 (en) 1997-11-13
EP0767671A1 (en) 1997-04-16
BR9406575A (pt) 1996-03-19
HU9503135D0 (en) 1996-01-29
JPH08509476A (ja) 1996-10-08
NO954390L (no) 1996-01-02

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C53 Correction of patent of invention or patent application
CB02 Change of applicant information

Address after: Quebec

Applicant after: Boehringer Ingelheim (Canada) Ltd.

Address before: Quebec

Applicant before: Research Center of the research company

COR Change of bibliographic data

Free format text: CORRECT: APPLICANT; FROM: BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. TO: BEHRINGERL INGEHUM CANADA CO., LTD.

C01 Deemed withdrawal of patent application (patent law 1993)
WD01 Invention patent application deemed withdrawn after publication