CN1125082C - 人类趋化因子β－8,趋化因子β－1和巨噬细胞炎性蛋白－4 - Google Patents

人类趋化因子β－8,趋化因子β－1和巨噬细胞炎性蛋白－4 Download PDF

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CN1125082C
CN1125082C CN95197892A CN95197892A CN1125082C CN 1125082 C CN1125082 C CN 1125082C CN 95197892 A CN95197892 A CN 95197892A CN 95197892 A CN95197892 A CN 95197892A CN 1125082 C CN1125082 C CN 1125082C
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nucleic acid
seq
continuous bases
polypeptide
cell
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CN1186501A (zh
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C·A·罗森
S·M·卢本
李浩东
M·D·艾德姆斯
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Human Genome Sciences Inc
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Human Genome Sciences Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
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    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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    • A—HUMAN NECESSITIES
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • A61P35/00—Antineoplastic agents
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/521—Chemokines
    • C07K14/523—Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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    • C07—ORGANIC CHEMISTRY
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    • C07K2319/00—Fusion polypeptide
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

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  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Toxicology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN95197892A 1995-05-05 1995-06-23 人类趋化因子β－8,趋化因子β－1和巨噬细胞炎性蛋白－4 Expired - Fee Related CN1125082C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44688195A 1995-05-05 1995-05-05
US08/446,881 1995-05-05

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CNA021471495A Division CN1515672A (zh) 1995-05-05 1995-06-23 人类趋化因子β-8,趋化因子β-1和巨噬细胞炎性蛋白-4

Publications (2)

Publication Number Publication Date
CN1186501A CN1186501A (zh) 1998-07-01
CN1125082C true CN1125082C (zh) 2003-10-22

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ID=23774170

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CNA021471495A Pending CN1515672A (zh) 1995-05-05 1995-06-23 人类趋化因子β-8,趋化因子β-1和巨噬细胞炎性蛋白-4
CN95197892A Expired - Fee Related CN1125082C (zh) 1995-05-05 1995-06-23 人类趋化因子β－8,趋化因子β－1和巨噬细胞炎性蛋白－4

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CNA021471495A Pending CN1515672A (zh) 1995-05-05 1995-06-23 人类趋化因子β-8,趋化因子β-1和巨噬细胞炎性蛋白-4

Country Status (8)

Country Link
EP (1) EP0871672A4 (fr)
JP (2) JPH11505417A (fr)
KR (1) KR19990008335A (fr)
CN (2) CN1515672A (fr)
AU (1) AU3134695A (fr)
CA (1) CA2220123A1 (fr)
MX (1) MX9708537A (fr)
WO (1) WO1996034891A1 (fr)

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US6811773B1 (en) 1993-12-22 2004-11-02 Human Genome Sciences, Inc. Human monocyte colony inhibitory factor (M-CIF) polypeptides
US6451562B1 (en) 1993-12-22 2002-09-17 Human Genome Sciences, Inc. Polypeptides encoding myeloid progenitor inhibitory factor-1 (MPIF-1) polynucleotides
US6488925B2 (en) 1993-12-22 2002-12-03 Human Genome Sciences, Inc. Macrophage inflammatory protein-4 (MIP-4) polypeptides
US6001606A (en) * 1994-03-08 1999-12-14 Human Genome Sciences, Inc. Polynucleotides encoding myeloid progenitor inhibitory factor-1 (MPIF-1) and polypeptides encoded thereby
US6495129B1 (en) 1994-03-08 2002-12-17 Human Genome Sciences, Inc. Methods of inhibiting hematopoietic stem cells using human myeloid progenitor inhibitory factor-1 (MPIF-1) (Ckbeta-8/MIP-3)
WO1997041230A2 (fr) * 1996-04-30 1997-11-06 Forssmann Wolf Georg Chemokines de type cc
EP0859842A4 (fr) * 1995-09-29 1999-02-24 Smithkline Beecham Corp FORMES COURTES DE LA CHIMIOKINE -g(b)-8
US6512103B1 (en) 1995-12-08 2003-01-28 Schering Corporation Mammalian chemokine reagents
US7888466B2 (en) 1996-01-11 2011-02-15 Human Genome Sciences, Inc. Human G-protein chemokine receptor HSATU68
US5912327A (en) * 1996-09-30 1999-06-15 Human Genome Sciences, Inc. Method of purifying chemokines from inclusion bodies
JP2001500382A (ja) * 1996-09-30 2001-01-16 ヒューマン ジノーム サイエンシーズ，インコーポレイテッド 骨髄前駆体阻害因子―１（ｍｐｉｆ―１）、単球コロニー阻害因子（ｍ―ｃｉｆ）、およびマクロファージ阻害因子―４（ｍｉｐ―４）で疾患状態を処置するための治療組成物および方法
US6632425B1 (en) 1997-03-20 2003-10-14 Human Genome Sciences, Inc. Chemokine compositions
ATE487737T1 (de) 1997-05-30 2010-11-15 Human Genome Sciences Inc 32 humane sekretierte proteine
WO1999023105A1 (fr) 1997-11-03 1999-05-14 Human Genome Sciences, Inc. Vegi, un inhibiteur de l'angiogenese et de la croissance tumorale
KR19990042713A (ko) * 1997-11-27 1999-06-15 허일섭 사람에서 분리한 c 6 베타-케모카인 lkn-1의 cdna 및 재조합 lkn-1의 제조방법
AU3072799A (en) 1998-03-19 1999-10-11 Human Genome Sciences, Inc. Cytokine receptor common gamma chain like
CA2332573A1 (fr) * 1998-07-06 2000-01-13 Elizabeth Esther Mary Bates Genes mammiferes ; transporteur du type prostaglandine de cellules dendritiques (dc-pgt), hdtea84, hsljd37r et rankl, chimiokine hcc5, proteines de desubiquitination 11 et 12 (dub11, dub12), md-1, md-2 et cycline e2, reactifs apparentes et procedes associes
EP0974357A1 (fr) 1998-07-16 2000-01-26 Schering-Plough Chemokines comme adjuvants de la réponse immunitaire
CA2350771A1 (fr) 1998-11-10 2000-05-18 Human Genome Sciences, Inc. Chemokine .beta.-7
AU1083401A (en) * 1999-10-14 2001-04-23 Human Genome Sciences, Inc. Methods of treating or preventing cell, tissue, and organ damage using human myeloid progenitor inhibitory factor-1 (mpif-1)
CA2387378A1 (fr) * 1999-10-25 2001-05-03 Euroscreen S.A. Chimiokines humaines phc-1 et phc-2 traitees
EP1167527A1 (fr) * 2000-06-22 2002-01-02 Euroscreen S.A. Chemokines humaines tronquées: PHC-1 et PHC-2
EP1278544A4 (fr) 2000-04-12 2004-08-18 Human Genome Sciences Inc Proteines hybrides d'albumine
WO2001096528A2 (fr) 2000-06-15 2001-12-20 Human Genome Sciences, Inc. Facteur de necrose tumorale humain delta et epsilon
EP1176200A3 (fr) 2000-06-20 2005-01-12 Switch Biotech Aktiengesellschaft Utilisation des polypeptides ou leurs acides nucléiques pour le diagnose ou traitement des maladies de la peau ou de la cicatrisation de blessures et leurs utilisations pour l'identification des substances pharmacologiquement actives
WO2002000939A2 (fr) 2000-06-28 2002-01-03 Diadexus, Inc. Procede de diagnostic, de surveillance, de determination du stade, d'imagerie et de traitement du cancer du colon
BR0113512A (pt) 2000-08-25 2005-05-10 Basf Plant Science Gmbh Polinucleotìdeos de planta que codificam novas prenil proteases
US6989247B2 (en) 2000-11-28 2006-01-24 Celltech R & D, Inc. Compositions and methods for diagnosing or treating psoriasis
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CA2220123A1 (fr) 1996-11-07
CN1186501A (zh) 1998-07-01
CN1515672A (zh) 2004-07-28
JP2003102486A (ja) 2003-04-08
KR19990008335A (ko) 1999-01-25
EP0871672A4 (fr) 1999-05-12
AU3134695A (en) 1996-11-21
JPH11505417A (ja) 1999-05-21
EP0871672A1 (fr) 1998-10-21
WO1996034891A1 (fr) 1996-11-07
MX9708537A (es) 1998-02-28

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