CN112472871A - 一种提高力学及抗凝血性能的生物瓣膜交联方法 - Google Patents
一种提高力学及抗凝血性能的生物瓣膜交联方法 Download PDFInfo
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- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
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- A—HUMAN NECESSITIES
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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- A—HUMAN NECESSITIES
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
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Abstract
Description
断裂拉伸强度/MPa | |
戊二醛对照组 | 24.20±2.143 |
实施例 | 19.97±0.58 |
相对血小板粘附量 | |
戊二醛对照组 | 0.29 |
实施例 | 0.17 |
Claims (10)
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CN202011421499.5A CN112472871B (zh) | 2020-12-08 | 2020-12-08 | 一种提高力学及抗凝血性能的生物瓣膜交联方法 |
PCT/CN2021/136200 WO2022121912A1 (zh) | 2020-12-08 | 2021-12-07 | 一种提高力学及抗凝血性能的生物瓣膜交联方法、生物瓣膜材料及其应用 |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113952513A (zh) * | 2021-11-29 | 2022-01-21 | 四川大学华西医院 | 一种抗衰败人工生物瓣膜及其制备方法和应用 |
WO2022121912A1 (zh) * | 2020-12-08 | 2022-06-16 | 吉林启明皓月生物科技有限公司 | 一种提高力学及抗凝血性能的生物瓣膜交联方法、生物瓣膜材料及其应用 |
CN115970060A (zh) * | 2021-11-17 | 2023-04-18 | 四川大学 | 一种双键后交联提高生物瓣膜材料抗钙化及抗凝血性的方法 |
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CN117504003A (zh) * | 2022-08-04 | 2024-02-06 | 吉林启明皓月生物科技有限公司 | 生物膜材料加工方法、生物膜材料以及人工生物瓣膜 |
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WO2022121912A1 (zh) * | 2020-12-08 | 2022-06-16 | 吉林启明皓月生物科技有限公司 | 一种提高力学及抗凝血性能的生物瓣膜交联方法、生物瓣膜材料及其应用 |
CN115970060A (zh) * | 2021-11-17 | 2023-04-18 | 四川大学 | 一种双键后交联提高生物瓣膜材料抗钙化及抗凝血性的方法 |
CN115970060B (zh) * | 2021-11-17 | 2024-04-30 | 四川大学 | 一种双键后交联提高生物瓣膜材料抗钙化及抗凝血性的方法 |
CN113952513A (zh) * | 2021-11-29 | 2022-01-21 | 四川大学华西医院 | 一种抗衰败人工生物瓣膜及其制备方法和应用 |
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