CN112472758A - Acid-reducing tea for relieving gout and preparation method thereof - Google Patents

Acid-reducing tea for relieving gout and preparation method thereof Download PDF

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CN112472758A
CN112472758A CN202011598156.6A CN202011598156A CN112472758A CN 112472758 A CN112472758 A CN 112472758A CN 202011598156 A CN202011598156 A CN 202011598156A CN 112472758 A CN112472758 A CN 112472758A
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parts
extract
superfine powder
acid
polysaccharide
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刘志伟
李明
何丽丽
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Wuhan Walksun Biotechnology Co ltd
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Wuhan Walksun Biotechnology Co ltd
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Abstract

The invention provides a deacidification tea for relieving gout and a preparation method thereof, wherein the raw materials comprise: 2-6 parts of sarcandra glabra polysaccharide, 1-6 parts of peach kernel superfine powder, 0.5-2 parts of safflower superfine powder, 0.5-5 parts of angelica extract, 0.5-3 parts of radix rehmanniae extract, 1-3 parts of achyranthes root extract, 1-5 parts of ligusticum wallichii extract, 1-5 parts of platycodon grandiflorum superfine powder, 1-5 parts of red paeony root superfine powder, 0.5-3 parts of fructus aurantii extract, 1-5 parts of liquorice extract, 1-5 parts of radix bupleuri extract, 0.5-5 parts of gentian extract, 0.5-5 parts of scutellaria baicalensis extract, 0.5-6 parts of gardenia extract, 0.5-3 parts of rhizoma alismatis extract, 1-2 parts of radix bupleuri extract, 0.5-3 parts of semen plantaginis superfine powder, 1-5 parts of xylo oligosaccharide, 0.02-0.5 part of dipotassium hydrogen phosphate and 0.05-0.2 part of sodium. The acid-reducing tea for relieving gout is safe to eat, free of toxic and side effects, capable of regulating qi and blood, promoting blood circulation to remove blood stasis, relieving spasm and dispelling wind, inducing diuresis to alleviate pain, expelling wind and reducing acid, promoting discharge of uric acid, capable of effectively relieving gout, simple and easy to operate, strong in reproducibility, and beneficial to large-scale production.

Description

Acid-reducing tea for relieving gout and preparation method thereof
Technical Field
The invention belongs to the field of acid-reducing tea, and particularly relates to acid-reducing tea for relieving gout and a preparation method thereof.
Background
Gout is a common and complex type of arthritis, which can be suffered by all ages, with higher incidence in men than women. Patients with gout often have sudden joint pain at night, the joint is in urgent attack, severe pain, edema, red swelling and inflammation appear at the joint, and the pain is slowly relieved until the pain disappears for days or weeks. Hyperuricemia is the basis of gout, and hyperuricemia are over-saturated in urine, so that urate is deposited in the renal tubule lumen or interstitium, and an acute inflammatory reaction is caused. At present, medicines for relieving gout mainly comprise nonsteroidal anti-inflammatory drugs and glucocorticoids, but the existing medicine relieving method is less in use, people prefer to adopt diet therapy, the diet therapy has no side effect, both symptoms and root causes are treated, diet is controlled, foods with rich purine content are strictly limited, and high-purine foods and high-fat foods, such as meat, wild flavor, seafood, yeast-containing foods and beverages, are reduced; eating food with low purine content, such as rice, wheat, starch, sorghum, egg, pig blood, duck blood, etc., as far as possible; at the same time, the health care wine can reduce weight, control weight and properly increase physical activity. In view of this, this patent is filed.
Disclosure of Invention
In order to solve the problems in the prior art, the invention provides an acid-reducing tea for relieving gout and a preparation method thereof. The acid-reducing tea for relieving gout is safe to eat, has no toxic or side effect, has the mutual cooperation of the raw materials, and has a good effect of relieving gout.
The invention aims to provide the acid-reducing tea for relieving gout. The invention also aims to provide two preparation methods of the acid-reducing tea for relieving gout. The acid-reducing tea is prepared from the following raw materials: 2-6 parts of sarcandra glabra polysaccharide, 1-6 parts of peach kernel superfine powder, 0.5-2 parts of safflower superfine powder, 0.5-5 parts of angelica extract, 0.5-3 parts of radix rehmanniae extract, 1-3 parts of achyranthes root extract, 1-5 parts of ligusticum wallichii extract, 1-5 parts of platycodon grandiflorum superfine powder, 1-5 parts of red paeony root superfine powder, 0.5-3 parts of fructus aurantii extract, 1-5 parts of liquorice extract, 1-5 parts of radix bupleuri extract, 0.5-5 parts of gentian extract, 0.5-5 parts of scutellaria baicalensis extract, 0.5-6 parts of gardenia extract, 0.5-3 parts of rhizoma alismatis extract, 1-2 parts of radix bupleuri extract, 0.5-3 parts of semen plantaginis superfine powder, 1-5 parts of xylo oligosaccharide, 0.02-0.5 part of dipotassium hydrogen phosphate and 0.05-0.2 part of sodium.
Further, the raw materials comprise the following components in parts by weight: 5 parts of sarcandra glabra polysaccharide, 4 parts of peach kernel superfine powder, 1 part of safflower superfine powder, 3 parts of angelica extract, 2 parts of radix rehmanniae extract, 2 parts of achyranthes extract, 3 parts of ligusticum wallichii extract, 3 parts of platycodon grandiflorum superfine powder, 3 parts of red paeony root superfine powder, 2 parts of fructus aurantii extract, 3 parts of liquorice extract, 3 parts of radix bupleuri extract, 3 parts of gentian extract, 3 parts of scutellaria baicalensis extract, 3 parts of gardenia extract, 2 parts of rhizoma alismatis extract, 1.5 parts of radix bupleuri extract, 1.5 parts of semen plantaginis superfine powder, 3 parts of xylo-oligosaccharide, 0.3 part of dipotassium hydrogen phosphate and 0.1 part of.
Further, the sarcandra glabra polysaccharide is prepared by the following method: pulverizing and sieving Sarcophyton xanthina, degreasing with ethyl acetate and petroleum ether respectively, adding into distilled water at a weight ratio of 1:20-30, adjusting pH to 4.5-5.5, and extracting in 85-95 deg.C water bath for 3-5 hr; taking the supernatant, cooling, carrying out enzymolysis to remove starch, and then centrifuging to obtain the supernatant; concentrating the supernatant, adding 95% diethyl ether 2-4 times the volume of the concentrated solution, precipitating overnight to obtain precipitate, and vacuum freeze drying the precipitate to obtain crude polysaccharide of Pseudopterogorgia fusca; dissolving in water to obtain solution, deproteinizing, decolorizing, dialyzing, and performing ion exchange column chromatography to obtain Xanthocorallinum hancockianum pure polysaccharide, and vacuum freeze drying to obtain Xanthocorallinum hancockianum polysaccharide.
Further, the preparation method of the acid-reducing tea for relieving gout is characterized by comprising the following steps: weighing the sarcandra glabra polysaccharide, the safflower superfine powder, the red paeony root superfine powder and the plantain seed superfine powder in proportion, mixing, and uniformly mixing to form mixed fine materials; (2) respectively crushing and mixing the other raw materials except the sarcandra glabra polysaccharide, the safflower superfine powder, the red paeony root superfine powder and the plantain seed superfine powder, uniformly mixing to form a material to be extracted, soaking the material to be extracted for 6-18 hours by using 60-90% of diethyl ether as a solvent, filtering, collecting filtrate, recovering diethyl ether, and concentrating into paste to form paste liquid; and (3) drying the paste obtained in the step (2) in vacuum, crushing, mixing with the mixed fine powder obtained in the step (1), uniformly mixing, and sieving to obtain the deacidification tea for relieving gout. Further, in the step (2), the crushing is carried out by adopting a wall breaking machine. Further, in the step (2), the fineness of the crushed particles is 100 meshes.
Further, in the step (3), the sieving is 400-mesh sieving.
Further, sterilizing the acid reducing tea for relieving gout, granulating into granules or powder by adopting a granulator, weighing and packaging to form the tea bag.
The invention has the beneficial effects that:
1. the acid-reducing tea for relieving gout disclosed by the invention adopts natural traditional Chinese medicinal materials and food materials, and retains bioactive components in the raw materials to the greatest extent through advanced processes such as strict screening, ether extraction, vacuum concentration, low-temperature drying and the like, so that the biological active components are reasonably matched, the absorption is effectively promoted, and the health-care effect of relieving gout is achieved;
2. the acid-reducing tea for relieving gout is safe to eat, has no toxic or side effect, regulates qi and blood, promotes blood circulation to remove blood stasis, relieves spasm, dispels wind, promotes diuresis, relieves pain, dispels wind, reduces acid, promotes discharge of uric acid, and can effectively relieve gout;
3. the preparation method of the acid-reducing tea for relieving gout is simple and easy to operate, has strong reproducibility and is beneficial to large-scale production.
Detailed description of the preferred embodiments
Example 1
The embodiment provides an acid-reducing tea for relieving gout, which is prepared from the following raw materials: the acid-reducing tea is prepared from the following raw materials: 2 parts of sarcandra glabra polysaccharide, 1 part of peach kernel superfine powder, 0.5 part of safflower superfine powder, 0.5 part of angelica extract, 0.5 part of radix rehmanniae extract, 1 part of achyranthes extract, 1 part of ligusticum wallichii extract, 1 part of platycodon grandiflorum superfine powder, 1 part of red paeony root superfine powder, 0.5 part of fructus aurantii extract, 1 part of liquorice extract, 1 part of radix bupleuri extract, 0.5 part of gentian extract, 0.5 part of scutellaria baicalensis extract, 0.5 part of gardenia extract, 0.5 part of rhizoma alismatis extract, 1 part of radix bupleuri extract, 0.5 part of semen plantaginis superfine powder, 1 part of xylo-oligosaccharide, 0.02 part of dipotassium hydrogen phosphate and 0.05 part of. The sarcandra glabra polysaccharide is prepared by the following method: pulverizing and sieving Sarcophyton xanthina, degreasing with ethyl acetate and petroleum ether respectively, adding into distilled water at a weight ratio of 1:20-30, adjusting pH to 4.5-5.5, and extracting in 85-95 deg.C water bath for 3-5 hr; taking the supernatant, cooling, carrying out enzymolysis to remove starch, and then centrifuging to obtain the supernatant; concentrating the supernatant, adding 95% diethyl ether 2-4 times the volume of the concentrated solution, precipitating overnight to obtain precipitate, and vacuum freeze drying the precipitate to obtain crude polysaccharide of Pseudopterogorgia fusca; dissolving in water to obtain solution, deproteinizing, decolorizing, dialyzing, and performing ion exchange column chromatography to obtain Xanthocorallinum hancockianum pure polysaccharide, and vacuum freeze drying to obtain Xanthocorallinum hancockianum polysaccharide. The preparation method of the acid-reducing tea for relieving gout is characterized by comprising the following steps: weighing the sarcandra glabra polysaccharide, the safflower superfine powder, the red paeony root superfine powder and the plantain seed superfine powder in proportion, mixing, and uniformly mixing to form mixed fine materials; (2) respectively crushing and mixing the other raw materials except the sarcandra glabra polysaccharide, the safflower superfine powder, the red paeony root superfine powder and the plantain seed superfine powder, uniformly mixing to form a material to be extracted, soaking the material to be extracted for 6-18 hours by using 60-90% of diethyl ether as a solvent, filtering, collecting filtrate, recovering diethyl ether, and concentrating into paste to form paste liquid; and (3) drying the paste obtained in the step (2) in vacuum, crushing, mixing with the mixed fine powder obtained in the step (1), uniformly mixing, and sieving to obtain the deacidification tea for relieving gout. In the step (2), the fineness of the crushed particles is 100 meshes. In the step (3), the sieving is 400-mesh sieving. Sterilizing the acid reducing tea for relieving gout, granulating into granules or powder by adopting a granulator, weighing and packaging to form the tea bag.
Example 2
The embodiment provides an acid-reducing tea for relieving gout, which is prepared from the following raw materials: the raw materials comprise the following components in parts by weight: 5 parts of sarcandra glabra polysaccharide, 4 parts of peach kernel superfine powder, 1 part of safflower superfine powder, 3 parts of angelica extract, 2 parts of radix rehmanniae extract, 2 parts of achyranthes extract, 3 parts of ligusticum wallichii extract, 3 parts of platycodon grandiflorum superfine powder, 3 parts of red paeony root superfine powder, 2 parts of fructus aurantii extract, 3 parts of liquorice extract, 3 parts of radix bupleuri extract, 3 parts of gentian extract, 3 parts of scutellaria baicalensis extract, 3 parts of gardenia extract, 2 parts of rhizoma alismatis extract, 1.5 parts of radix bupleuri extract, 1.5 parts of semen plantaginis superfine powder, 3 parts of xylo-oligosaccharide, 0.3 part of dipotassium hydrogen phosphate and 0.1 part of. The sarcandra glabra polysaccharide is prepared by the following method: pulverizing and sieving Sarcophyton xanthina, degreasing with ethyl acetate and petroleum ether respectively, adding into distilled water at a weight ratio of 1:20-30, adjusting pH to 4.5-5.5, and extracting in 85-95 deg.C water bath for 3-5 hr; taking the supernatant, cooling, carrying out enzymolysis to remove starch, and then centrifuging to obtain the supernatant; concentrating the supernatant, adding 95% diethyl ether 2-4 times the volume of the concentrated solution, precipitating overnight to obtain precipitate, and vacuum freeze drying the precipitate to obtain crude polysaccharide of Pseudopterogorgia fusca; dissolving in water to obtain solution, deproteinizing, decolorizing, dialyzing, and performing ion exchange column chromatography to obtain Xanthocorallinum hancockianum pure polysaccharide, and vacuum freeze drying to obtain Xanthocorallinum hancockianum polysaccharide. The preparation method of the acid-reducing tea for relieving gout is characterized by comprising the following steps: weighing the sarcandra glabra polysaccharide, the safflower superfine powder, the red paeony root superfine powder and the plantain seed superfine powder in proportion, mixing, and uniformly mixing to form mixed fine materials; (2) respectively crushing and mixing the other raw materials except the sarcandra glabra polysaccharide, the safflower superfine powder, the red paeony root superfine powder and the plantain seed superfine powder, uniformly mixing to form a material to be extracted, soaking the material to be extracted for 6-18 hours by using 60-90% of diethyl ether as a solvent, filtering, collecting filtrate, recovering diethyl ether, and concentrating into paste to form paste liquid; and (3) drying the paste obtained in the step (2) in vacuum, crushing, mixing with the mixed fine powder obtained in the step (1), uniformly mixing, and sieving to obtain the deacidification tea for relieving gout. In the step (2), the crushing is carried out by adopting a wall breaking machine, and the fineness of the crushed particles is 100 meshes. In the step (3), the sieving is 400-mesh sieving. Sterilizing the acid reducing tea for relieving gout, granulating into granules or powder by adopting a granulator, weighing and packaging to form the tea bag.
Example 3
The embodiment provides an acid-reducing tea for relieving gout, which is prepared from the following raw materials: the invention also aims to provide two preparation methods of the acid-reducing tea for relieving gout. The acid-reducing tea is prepared from the following raw materials: 6 parts of sarcandra glabra polysaccharide, 6 parts of peach kernel superfine powder, 2 parts of safflower superfine powder, 5 parts of angelica extract, 3 parts of radix rehmanniae extract, 3 parts of achyranthes extract, 5 parts of ligusticum wallichii extract, 5 parts of platycodon grandiflorum superfine powder, 5 parts of red paeony root superfine powder, 3 parts of fructus aurantii extract, 5 parts of liquorice extract, 5 parts of radix bupleuri extract, 5 parts of gentian extract, 5 parts of scutellaria baicalensis extract, 6 parts of gardenia extract, 3 parts of rhizoma alismatis extract, 2 parts of radix bupleuri extract, 3 parts of semen plantaginis superfine powder, 5 parts of xylo-oligosaccharide, 0.5 part of dipotassium hydrogen phosphate and 0.2 part of. The sarcandra glabra polysaccharide is prepared by the following method: pulverizing and sieving Sarcophyton xanthina, degreasing with ethyl acetate and petroleum ether respectively, adding into distilled water at a weight ratio of 1:20-30, adjusting pH to 4.5-5.5, and extracting in 85-95 deg.C water bath for 3-5 hr; taking the supernatant, cooling, carrying out enzymolysis to remove starch, and then centrifuging to obtain the supernatant; concentrating the supernatant, adding 95% diethyl ether 2-4 times the volume of the concentrated solution, precipitating overnight to obtain precipitate, and vacuum freeze drying the precipitate to obtain crude polysaccharide of Pseudopterogorgia fusca; dissolving in water to obtain solution, deproteinizing, decolorizing, dialyzing, and performing ion exchange column chromatography to obtain Xanthocorallinum hancockianum pure polysaccharide, and vacuum freeze drying to obtain Xanthocorallinum hancockianum polysaccharide. The preparation method of the acid-reducing tea for relieving gout comprises the following steps: weighing the sarcandra glabra polysaccharide, the safflower superfine powder, the red paeony root superfine powder and the plantain seed superfine powder in proportion, mixing, and uniformly mixing to form mixed fine materials; (2) respectively crushing and mixing the other raw materials except the sarcandra glabra polysaccharide, the safflower superfine powder, the red paeony root superfine powder and the plantain seed superfine powder, uniformly mixing to form a material to be extracted, soaking the material to be extracted for 6-18 hours by using 60-90% of diethyl ether as a solvent, filtering, collecting filtrate, recovering diethyl ether, and concentrating into paste to form paste liquid; and (3) drying the paste obtained in the step (2) in vacuum, crushing, mixing with the mixed fine powder obtained in the step (1), uniformly mixing, and sieving to obtain the deacidification tea for relieving gout. And (3) crushing by using a wall breaking machine in the step (2), wherein the fineness of the crushed particles is 100 meshes in the step (2). In the step (3), the sieving is 400-mesh sieving. Sterilizing the acid reducing tea for relieving gout, granulating into granules or powder by adopting a granulator, weighing and packaging to form the tea bag.
And (3) clinical trials:
1.1 clinical data 240 gout patients admitted to the traditional Chinese medicine hospital in Hubei province in 2018, 1 month-2019, were selected as observation targets and randomly divided into an observation group and a control group, wherein 120 gout patients in each group were 36-56 years old.
1.2 methods the control group used oral indomethacin enteric coated tablets of 30mg, 3 times daily. The observation group was then relieved with the powder composition of example two: the medicine is dissolved in about 300mL of boiled water and is taken orally 3 times, 2 weeks is a treatment course, and 6 treatment courses are relieved.
1.3 observing the clinical curative effect and adverse reaction occurrence of two groups of patients by observing indexes. Clinical ineffectiveness: the clinical symptoms of the patients and the knee joint function have no obvious change; the clinical effect is shown: the clinical symptoms of the patient completely disappear, and the knee joint function returns to normal; the clinical effect is as follows: the clinical symptoms of the patients are effectively controlled, and the knee joint function is improved by more than or equal to 50 percent compared with that before the relief.
1.4 statistical analysis was performed using SPSS16.0 statistical software.
2 results
2.1 clinical efficacy observed groups of two groups of patients had significantly better clinical efficacy than the control group (P < 0.05), as shown in Table 1.
TABLE 1 clinical efficacy of two groups of patients [ n (%) ]
Group of Show effect Is effective Invalidation Effective rate of treatment
Observation group (120) 45 46 9 91.0
Control group (120) 30 47 23 77
X2 6.523 6.554 11.636 11.714
P value 0.000 0.000 0.000 0.000
Adverse reaction incidence rates of the two groups of patients the adverse reaction incidence rate of the observed group was significantly lower than that of the control group (P < 0.05), as shown in Table 2.
TABLE 2 incidence of adverse reactions in two groups of patients
Group of Allergy (S) Nausea Diarrhea (diarrhea) Effective rate of treatment
Observation group (120) 0 2 0 1.6
Control group (120) 4 6 4 11.6
X2 1.691 3.601 2.714 7.308
P value 0.147 0.402 0.328 0.000
In the research and observation, the clinical curative effect and the adverse reaction incidence rate of an observation group are obviously superior to those of a control group (P is less than 0.05), which shows that the composition for relieving gout has better curative effect and safety in clinical relief, and is worthy of popularization and use in clinic.
The above description is only for the specific embodiments of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art can easily conceive of the changes or substitutions within the technical scope of the present invention, and all the changes or substitutions should be covered within the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the appended claims.

Claims (7)

1. The acid-reducing tea for relieving gout is prepared from the following raw materials: 2-6 parts of sarcandra glabra polysaccharide, 1-6 parts of peach kernel superfine powder, 0.5-2 parts of safflower superfine powder, 0.5-5 parts of angelica extract, 0.5-3 parts of radix rehmanniae extract, 1-3 parts of achyranthes root extract, 1-5 parts of ligusticum wallichii extract, 1-5 parts of platycodon grandiflorum superfine powder, 1-5 parts of red paeony root superfine powder, 0.5-3 parts of fructus aurantii extract, 1-5 parts of liquorice extract, 1-5 parts of radix bupleuri extract, 0.5-5 parts of gentian extract, 0.5-5 parts of scutellaria baicalensis extract, 0.5-6 parts of gardenia extract, 0.5-3 parts of rhizoma alismatis extract, 1-2 parts of radix bupleuri extract, 0.5-3 parts of semen plantaginis superfine powder, 1-5 parts of xylo oligosaccharide, 0.02-0.5 part of dipotassium hydrogen phosphate and 0.05-0.2 part of sodium.
2. The acid-reducing tea for relieving gout as claimed in claim 1, wherein the acid-reducing tea is prepared from the following raw materials in parts by weight: 5 parts of sarcandra glabra polysaccharide, 4 parts of peach kernel superfine powder, 1 part of safflower superfine powder, 3 parts of angelica extract, 2 parts of radix rehmanniae extract, 2 parts of achyranthes extract, 3 parts of ligusticum wallichii extract, 3 parts of platycodon grandiflorum superfine powder, 3 parts of red paeony root superfine powder, 2 parts of fructus aurantii extract, 3 parts of liquorice extract, 3 parts of radix bupleuri extract, 3 parts of gentian extract, 3 parts of scutellaria baicalensis extract, 3 parts of gardenia extract, 2 parts of rhizoma alismatis extract, 1.5 parts of radix bupleuri extract, 1.5 parts of semen plantaginis superfine powder, 3 parts of xylo-oligosaccharide, 0.3 part of dipotassium hydrogen phosphate and 0.1 part of.
3. The acid-reducing tea for relieving gout as claimed in claims 1-2, wherein the Xanthomonas campestris polysaccharide is prepared by the following method: pulverizing and sieving Sarcophyton xanthina, degreasing with ethyl acetate and petroleum ether respectively, adding into distilled water at a weight ratio of 1:20-30, adjusting pH to 4.5-5.5, and extracting in 85-95 deg.C water bath for 3-5 hr; taking the supernatant, cooling, carrying out enzymolysis to remove starch, and then centrifuging to obtain the supernatant; concentrating the supernatant, adding 95% diethyl ether 2-4 times the volume of the concentrated solution, precipitating overnight to obtain precipitate, and vacuum freeze drying the precipitate to obtain crude polysaccharide of Pseudopterogorgia fusca; dissolving in water to obtain solution, deproteinizing, decolorizing, dialyzing, and performing ion exchange column chromatography to obtain Xanthocorallinum hancockianum pure polysaccharide, and vacuum freeze drying to obtain Xanthocorallinum hancockianum polysaccharide.
4. The preparation method of the acid-reducing tea for relieving gout as claimed in any one of claims 1 to 3, which comprises the following steps: weighing the sarcandra glabra polysaccharide, the safflower superfine powder, the red paeony root superfine powder and the plantain seed superfine powder in proportion, mixing, and uniformly mixing to form mixed fine materials; (2) respectively crushing and mixing the other raw materials except the sarcandra glabra polysaccharide, the safflower superfine powder, the red paeony root superfine powder and the plantain seed superfine powder, uniformly mixing to form a material to be extracted, soaking the material to be extracted for 6-18 hours by using 60-90% of diethyl ether as a solvent, filtering, collecting filtrate, recovering diethyl ether, and concentrating into paste to form paste liquid; and (3) drying the paste obtained in the step (2) in vacuum, crushing, mixing with the mixed fine powder obtained in the step (1), uniformly mixing, and sieving to obtain the deacidification tea for relieving gout.
5. The preparation method of the acid-reducing tea for relieving gout as claimed in claim 4, wherein in the step (2), the crushing is carried out by a wall breaking machine.
6. The preparation method of the acid-reducing tea for relieving gout as claimed in claim 4, wherein in the step (2), the particle fineness after the crushing is 100 meshes.
7. The preparation method of the acid-reducing tea for relieving gout as claimed in claim 4, wherein in the step (3), the sieving is performed by a 400-mesh sieve.
CN202011598156.6A 2020-12-29 2020-12-29 Acid-reducing tea for relieving gout and preparation method thereof Pending CN112472758A (en)

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