CN103961551A - Traditional Tibetan medicine for treating diabetes - Google Patents
Traditional Tibetan medicine for treating diabetes Download PDFInfo
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- CN103961551A CN103961551A CN201410224564.3A CN201410224564A CN103961551A CN 103961551 A CN103961551 A CN 103961551A CN 201410224564 A CN201410224564 A CN 201410224564A CN 103961551 A CN103961551 A CN 103961551A
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Abstract
The invention discloses a traditional Tibetan medicine for treating diabetes, which is prepared from an active component or active component and pharmaceutically acceptable auxiliary materials, wherein the active component is prepared from coriander fruit, celery seed, emblic leafflower fruit, rhizoma polygonati, cortex berberidis, wolfberry bark and Gymnadenia conopsea according to certain parts by weight. The traditional Tibetan medicine can be prepared into any common oral preparation formulation. The traditional Tibetan medicine has the effects of nourishing the kidney-yin, moistening the lung, clearing away the stomach-heat, promoting salivation, quenching thirst, invigorating qi and lowering the blood sugar. The traditional Tibetan medicine is used for diabetes caused by deficiency of both qi and yin, which has the symptoms of polydipsia, polyphagia, diuresis, marasmus, asthenia, spontaneous perspiration, night sweat, short breath, laziness to speak, dysphoria with feverish sensation in chest, palpitation and insomnia, numbness and pain of limbs, soreness and weakness of limbs, dizziness and tinnitus, constipation, glucose in urine, high blood sugar and the like.
Description
Technical field
The present invention relates to a kind of Tibetan medicine for the treatment of diabetes, belong to Tibetan medicine field.
Background technology
Diabetes are a kind of common metabolism endocrinopathyes, and World Health Organization (WHO) is classified as one of ten large difficult disease.Sickness rate is high, and has the trend rising year by year; According to New York Times, a current research demonstration, the diabetes prevalence of China occupy first place, the world, but also is continuing deterioration.The aforementioned current research that is published in " JAMA " shows, the diabetes prevalence of China has just exceeded the U.S.: 11.6% Chinese adult suffers from this disease, and the U.S. is 11.3%.1980, the diabetes prevalence of China was less than 1%.Diabetes mellitus in China patient total number of persons reaches 1.14 hundred million, rises 2,200 ten thousand than estimative figure in 2007, that is to say, the diabetics in the whole world about 1/3rd is all in China.More allow people's worry, this research is tested 9.9 ten thousand people nearly, and the people's blood glucose that finds that there is half has reached " prediabetes " level.Research is pointed out: " China is one of country that Asia diabetes prevalence is the highest at present, be also in the world the maximum country of the absolute number of diabetics ".
Modern medicine there will be many untoward reaction in various degree in the process for the treatment of diabetes, and Chinese medicine is slow to the therapeutical effect of diabetes, but belong to the category that effects a permanent cure, when blood glucose declines, body constitution is synchronously strengthened, chronic complicating diseases is had to good preventive and therapeutic action.
Tibetan medicine's theory is thought: trouble diabetes are relevant to " three categories of etiologic factors " imbalance of self body.Under normal circumstances, human body " dragon " (being equivalent to wind, gas), " red bar " (refer to gallbladder, fire, the root that causes all heat symptom-complex diseases), " Baconic " (refer to water, soil, the root that causes all sympotoms caused by cold factors diseases) " three categories of etiologic factors " in poised state, could keep the normal operation of body function.The pathogenic factor of diabetes is because serious unbalance appears in human body " three categories of etiologic factors ", conventionally comparatively significant performance is that " red bar " and " dragon " are contained partially, " Baconic " is on the weak side, cause seven large cereal nutrients of human body (precise and tiny, blood, muscle, fat, skeleton, marrow, seminal fluid) can not normally decompose, excretion and conveying, dirty thing in blood is assembled too much, the vitals function that causes the human bodies such as heart kidney is impaired, show as clinically xerostomia easily hungry, urine urgency-frequency, weak dreaminess, the symptom such as become thin, simultaneously with heating, visual deterioration, the symptoms such as skin pruritus.Tibetan medicine, by conditioning, balance " three categories of etiologic factors ", reaches and falls " red bar " and " dragon ", and righting " Baconic " is object, make the large cereal nutrient of seven in body be decomposed normally and drain, reduce harmful composition in blood, make pancreas obtain nutrition, islet function progressively recovers; Regulate dietary simultaneously, the custom of making the life better, finally reach nutrition pancreas, reduce blood glucose, improve complication, improve the object of patient live and work quality.
There is tight demand in the Tibetan medicinal preparation that therefore, people better treat diabetes to curative effect.Up to now, also do not find any report about Tibetan medicinal composition of the present invention and preparation method thereof.The inventor, through research repeatedly, and by the checking repeatedly of animal and clinical trial, has finally found the Tibetan medicine oral drugs that have the treatment of better curative effect diabetes, thereby has completed the present invention.
Summary of the invention
The object of the invention is just to provide a kind of Tibetan medicine of more effectively treating diabetes and preparation method thereof.
The present invention is a kind of Tibetan medicine, be to be made or be made up of active component and pharmaceutically acceptable adjuvant by active component, wherein said active component is to be made up of following bulk drugs: Fructus Coriandri sativi, seed of Herba Apii graveolentis, Fructus Phyllanthi, Rhizoma Polygonati, Radix Berberidis Amurensis, Cortex Lycii, Rhizoma Gymnadeniae.
It has selected Fructus Coriandri sativi, seed of Herba Apii graveolentis, Fructus Phyllanthi, Rhizoma Polygonati, Radix Berberidis Amurensis, Cortex Lycii, Rhizoma Gymnadeniae to combine as crude drug, and wherein (1) Fructus Coriandri sativi is the dry mature fruit of samphire coriander Coriandrum sativum L..There is heat clearing away, induce sweat, effect of stomach invigorating.For " Baconic wood cloth " disease, dyspepsia, inappetence, thirsty etc.(2) seed of Herba Apii graveolentis is the dry fruit of samphire Herba Apii graveolentis Apium graveolens L..There is clearing heat to ease the stomach, reduce phlegm and wash worm, effect of promoting the production of body fluid to quench thirst.For Baconic's disease, pathogenic heat in the stomach phlegm syndrome, purple phlegm syndrome, xerostomia wish drink.(3) Fructus Phyllanthi is the dry mature fruit of euphorbia plant Fructus Phyllanthi Phyllanthusemblica L..There is clearing away heat and cooling blood, the function of promoting digestion and invigorating the stomach.For heat in blood blood stasis, dyspepsia, abdominal distention, cough, laryngalgia, xerostomia.There is anti-myocardial necrosis and blood fat reducing, antimutagenic, antibacterial, the pharmacological actions such as antioxidation; The clinical hypertension that is used for the treatment of, hepatitis B, chronic pharyngitis, slow down aging etc., have good adjusting blood fat effect to diabetics.(4) Rhizoma Polygonati is the dry rhizome of liliaceous plant Yunnan Rhizoma Polygonati Palygonatum kingianum Coll.et Hemsl. Rhizoma Polygonati Polygonatum sibiricum Red. or Polygonatum cyrtonema Hua Polygonatum cyrtonema Hua.There is spleen reinforcing lung moistening, effect of supplementing QI and nourishing YIN.Weak for body void, shortness of breath and palpitation, dryness of the lung dry cough, diabetes.There is increase coronary flow, regulating blood fat and decreasing blood sugar, defying age and enhancing immunity; immunomodulating, has protective effect to chemical liver injury, the pharmacological actions such as antiinflammatory and antiviral; the clinical coronary heart disease that is used for the treatment of, hyperlipemia, diabetes; leukopenia; pulmonary tuberculosis, chronic hepatitis, mental and do not have enough sleep; headache, sexual impotence etc.(5) Radix Berberidis Amurensis is the dry skin of Berberidaceae plant kansu barberry bark Berbeis kansuensis Schneid..There is place heat clearly, relieving heat toxin, the effect of holding back yellow fluid.For epidemic disease, old calentura, grasserie.Berberine has hypoglycemic activity.(6) Cortex Lycii is the dry root bark of matrimony vine of solanaceae plant Lycium chinense Mill. or lycium barbarum Lycium barbarum L..There is removing heat from blood except steaming, effect of lung heat clearing pathogenic fire reducing.For deficiency of YIN hectic fever, hectic fever due to YIN-deficiency night sweat, cough due to lung-heat, spitting of blood, epistaxis, interior-heat is quenched one's thirst etc.Root bark is containing cinnamic acid and volume aldehydes matter, betanin; There is blood pressure lowering, blood sugar lowering, the pharmacological action such as antipyretic.(7) Rhizoma Gymnadeniae is the dry tuber of orchid Rhizoma Gymnadeniae Gymnadenia conopsea (L.) R.Br..Have and tonify Qi of the kidney, effect of spermatogenesis lung moistening.For pneumonopathy, cough and asthma due to lung deficiency, meat poison, seminal emission sexual impotence.Make each efficacy of drugs produce synergism these drug regimens, thereby can effectively treat atrophic gastritis.
The consumption of Tibetan medicine active component of the present invention is also groped in a large number to sum up through inventor and is drawn, each crude drug consumption for all having good therapeutic effect within the scope of following concrete weight proportion:
Fructus Coriandri sativi 50～100g, seed of Herba Apii graveolentis 25～75g, Fructus Phyllanthi 25～75g, Rhizoma Polygonati 20～60g, Radix Berberidis Amurensis 20～60g, Cortex Lycii 15～45g, Rhizoma Gymnadeniae 10～30g.
Be preferably: Fructus Coriandri sativi 60～90g, seed of Herba Apii graveolentis 40～60g, Fructus Phyllanthi 40～60g, Rhizoma Polygonati 32～48g, Radix Berberidis Amurensis 32～48g, Cortex Lycii 24～36g, Rhizoma Gymnadeniae 16～24g.
More preferably: Fructus Coriandri sativi 75g, seed of Herba Apii graveolentis 50g, Fructus Phyllanthi 50g, Rhizoma Polygonati 40g, Radix Berberidis Amurensis 40g, Cortex Lycii 30g, Rhizoma Gymnadeniae 20g.
The preparation of Tibetan medicine active component of the present invention can be that direct the crude drug of above-mentioned consumption co-grinding is made; The conventional method that also crude drug of above-mentioned consumption can be adopted to Chinese medicine preparation makes as decoction and alcohol sedimentation technique or ethanol extract from water precipitation (referring to Cao Chunlin chief editor's " pharmaceutics of Chinese drugs " 73rd～74 pages, Science and Technology of Shanghai publishing house publishes in November, 1986).
The active component of Tibetan medicine of the present invention can add various conventional adjuvant required while preparing different dosage form, if disintegrating agent, lubricant, binding agent etc. are with conventional method of Chinese medicinal (" pharmaceutics of Chinese drugs " edited referring to Cao Chunlin, Science and Technology of Shanghai publishing house publishes in November, 1986) be prepared into any conventional peroral dosage form, as powder, pill, capsule, granule, tablet etc.
Tibetan medicine of the present invention has nourishing kidney yin, lung moistening clearing stomach, promoting the production of body fluid to quench thirst, effect of QI invigorating blood sugar lowering.For the diabetes due to deficiency of both QI and YIN, disease is seen: polydipsia, polyphagia, polyuria, become thin, spiritlessness and weakness, spontaneous sweating, the lazy speech of breathing hard, dysphoria with feverish sensation in the chest palms and soles, palpitation and insomnia, limb fiber crops pain, extremity are aching and limp, dizziness and tinnitus, be hard and dry, glucose in urine and blood sugar increasing etc.
The usage and dosage of Tibetan medicine of the present invention is: oral; A 1～1.5g, 1～3 time on the one.
[detailed description of the invention]
Carry out by the following examples further to set forth the preparation method of Tibetan medicine of the present invention.
The preparation of [embodiment 1] Tibetan medicine powder of the present invention:
Take Fructus Coriandri sativi 75g, seed of Herba Apii graveolentis 50g, Fructus Phyllanthi 50g, Rhizoma Polygonati 40g, Radix Berberidis Amurensis 40g, Cortex Lycii 30g, Rhizoma Gymnadeniae 20g, be jointly ground into fine powder after mixing, mix, subpackage, obtains powder.
The preparation of [embodiment 2] Tibetan medicine pill of the present invention:
Take Fructus Coriandri sativi 50g, seed of Herba Apii graveolentis 25g, Fructus Phyllanthi 25g, Rhizoma Polygonati 20g, Radix Berberidis Amurensis 20g, Cortex Lycii 15g, Rhizoma Gymnadeniae 10g, after mixing, be jointly ground into fine powder, mix, with water pill, 60 DEG C of following being dried, polishing, packaging, obtains pill.
The preparation of [embodiment 3] Tibetan medicine granule of the present invention:
Take Fructus Coriandri sativi 100g, seed of Herba Apii graveolentis 75g, Fructus Phyllanthi 75g, Rhizoma Polygonati 60g, Radix Berberidis Amurensis 60g, Cortex Lycii 45g, Rhizoma Gymnadeniae 30g, after mixing, be jointly ground into fine powder, mix, add adjuvant granulation, 60 DEG C of following being dried, granulate, subpackage, obtains granule.
The preparation of [embodiment 4] Tibetan medicine capsule of the present invention:
Take Fructus Coriandri sativi 60g, seed of Herba Apii graveolentis 40g, Fructus Phyllanthi 40g, Rhizoma Polygonati 32g, Radix Berberidis Amurensis 32g, Cortex Lycii 24g, Rhizoma Gymnadeniae 16g, be jointly ground into fine powder after mixing, mix, pack gelatine capsule into, subpackage, obtains capsule.
The preparation of [embodiment 5] Tibetan medicine tablet of the present invention:
Take Fructus Coriandri sativi 90g, seed of Herba Apii graveolentis 60g, Fructus Phyllanthi 60g, Rhizoma Polygonati 48g, Radix Berberidis Amurensis 48g, Cortex Lycii 36g, Rhizoma Gymnadeniae 24g, after mixing, be jointly ground into fine powder, mix, add adjuvant granulation, 60 DEG C of following being dried, granulate, tabletting, subpackage, obtains tablet.
Further set forth below the beneficial effect of Tibetan medicine of the present invention by test example, these test examples have comprised pharmacodynamics test and the clinical observation on the therapeutic effect test of Tibetan medicine embodiment 1 powder of the present invention.
[test example 1] Tibetan medicine embodiment 1 powder of the present invention is to the hypoglycemic pharmacodynamics test of diabetic mice:
Test material: anthology invention Tibetan medicine embodiment 1 powder; JIANGZHILING PIAN (phenformin hydrochloride tablet), 25mg/ sheet, lot number: 20100813, pharmaceutical factory of Jintan City of Jiangsu Province produces; Alloxan: Signa company provides; Glucose oxidase enzyme reagent kit: Wenzhou Dong Ou biological engineering company limited produces; Insulin test kit: China Atomic Energy Science Research Institute's coordination rope institute provides; SD rat, Kunming mouse, provided by Qinghai Province's Experimental Animal Center.
Experimental technique: get Kunming kind healthy mice, male and female half and half, body weight 20 ± 2g, mice fasting 32h(can't help water), tail vein injection alloxan 100mg/kg, 72h posterior orbit venous blood sampling is measured fasting glucose (12h on an empty stomach), get blood glucose value >=11.1mmol/L, 50 is diabetes moulding mice, is divided at random five groups, 10 every group, press respectively Time of Administration gavage Tibetan medicine embodiment 1 powder (1g/kg of the present invention, 2g/kg, 4g/kg) basic, normal, high dosage group, JIANGZHILING PIAN group (0.1g/kg.d) and normal saline equivalent blank group.10 of normal mouse matched groups in addition, same gavage equivalent normal saline.After administration 10d, administration 11d is measured by eye socket venous blood sampling: blood glucose adopts glucose oxidase method; Serum insulin adopts radioimmunology.
Carbohydrate tolerance test: respectively organize mice by the glucose load filling amount of 2g/kg, 30min, 60min and the 120min mensuration blood glucose of respectively taking a blood sample after gavage, the mensuration of carbohydrate tolerance still adopts glucose oxidase method.
Experimental result: Tibetan medicine embodiment 1 powder of the present invention is measured the impact of diabetic mice hyperglycemia.The results are shown in Table 1.
The impact (n=10) of table 1 Tibetan medicine embodiment 1 powder of the present invention on diabetic mice hyperglycemia
Blood glucose (mmol/L) after blood glucose (mmol/L) medicine before group number of animals dosage (g/kg) medicine
Normal group 10 6.76 ± 1.12 7.07 ± 1.05
* *
Model control group 10 12.38 ± 1.46 12.59 ± 2.14
Low dose group 10 1 12.43 ± 1.74 10.79 ± 1.83
△
Middle dosage group 10 2 12.58 ± 1.38 9.17 ± 2.28
*
High dose group 10 4 12.53 ± 1.34 8.94 ± 2.17
*
JIANGZHILING PIAN group 10 0.1 12.38 ± 1.58 8.93 ± 2.14
*
Illustrate: with model control group comparison:
△p>0.05;
*p<0.05;
*p<0.01;
* *p<0.001.
As seen from Table 1: model control group blood sugar detection result relatively has notable difference with Normal group, blood sugar increasing more than one times, illustrates mice tail vein injection alloxan 100mg/kg on an empty stomach, and it is successful making hyperglycemia model; Tibetan medicine embodiment 1 powder of the present invention has hypoglycemic activity in using dosage test, and along with its effect of increase of dosage strengthens, high dose (4g/kg) effect is the strongest, its effect and relatively no significant difference of insoral group, both all can make mice hyperglycemia be down to almost normal value (certainly also slightly higher).That is to say, Tibetan medicine embodiment 1 powder of the present invention has hypoglycemic activity, and suitable with blood sugar lowering Western medicine JIANGZHILING PIAN hypoglycemic effect.
The mensuration of the impact of Tibetan medicine embodiment 1 powder of the present invention on diabetic mice serum insulin.The results are shown in Table 2.
The impact (n=10) of table 2 Tibetan medicine embodiment 1 powder of the present invention on diabetic mice serum insulin
Group number of animals dosage (g/kg) serum insulin (mu/L)
Normal group 10 26.58 ± 3.54
*
Model control group 10 12.17 ± 2.68
Low dose group 10 1 15.24 ± 3.27
△
Middle dosage group 10 2 17.16 ± 1.44
△
High dose group 10 4 19.93 ± 2.17
*
JIANGZHILING PIAN group 10 0.1 19.42 ± 1.58
△
Illustrate: with model control group comparison:
*p<0.01;
*p<0.05;
△p>0.05.
As seen from Table 2: model control group serum insulin relatively reduces by more than 50 with Normal group, P<0.01, illustrate that the β cell in moulding mouse islets is destroyed in a large number, cause serum insulin in body obviously to decline (and causing blood glucose to rise).After the Tibetan medicine embodiment of the present invention 1 powder treatment of giving diabetic mice gavage various dose, serum islet have increase in various degree, and proportional with dosage, show that Tibetan medicine embodiment 1 powder of the present invention is improved the trend of diabetic mice serum insulin levels.
Carbohydrate tolerance test is measured.The results are shown in Table 3.
The impact (n=10) of table 3 Tibetan medicine embodiment 1 powder of the present invention on hyperglycemia model mice oral glucose carbohydrate tolerance
Group dosage (g/kg) serum insulin (mmol/L)
0min 30min 60min 120min
Normal group 6.04 ± 1.52 8.91 ± 1.35 9.01 ± l.34 7.83 ± 1.64
Model control group 12.15 ± 2.17
##20.45 ± 2.17
##20.95 ± 2.03
##18.87 ± 2.04
##
Low dose group 1 12.35 ± 1.84
19.23 ± 1.95**, 17.87 ± 1.64**, 14.11 ± 2.08*
Middle dosage group 2 12.53 ± 2.02
18.94 ± 2.05*, 17.07 ± 2.06**, 12.77 ± 1.63*
High dose group 4
12.11 ± 2.13 18.26 ± 1.93**, 16.81 ± 1.84**, 11.97 ± 1.93**
JIANGZHILING PIAN group 0.1 12.33 ± 2.17 18.14* ± 1.64** 17.94* ± 1.65** 11.14 ± 2.13*
Illustrate: with Normal group comparison:
##p<0.01, with model group comparison
*p<0.05,
*p<0.01.
As seen from Table 3: the hyperglycemia mice that Tibetan medicine embodiment 1 powder of the present invention causes alloxan, after oral administration, there is reduction blood glucose, and blood sugar increasing time and reduce blood glucose peak concentration after deferrable mice oral glucose.This explanation Tibetan medicine embodiment 1 powder of the present invention may weaken the damage of alloxan to beta Cell of islet or improve the function of damaged cell, is of value to the condition of illness of diabetes-alleviating mice.
The observation of curative effect of [test example 2] Tibetan medicine embodiment 1 powder of the present invention to diabetes patient's hypoglycemic activity:
Physical data: my Out-patient Department Inpatients with Diabetic Mellitus, have a medical check-up undesired, fat or become thin.Polydipsia, polyuria, polyphagia symptom are obvious, fasting glucose >=7.8mmol/L, and OGTT checks blood glucose >=11.lmmol/L after (being 75 grams of oral glucoses) 2h, is diagnosed as diabetes type II patient 123 examples, wherein male 68 examples, female's 55 examples, are used as clinical observation object.In 123 examples, be divided at random treatment group 63 examples (man 35, female 28); Matched group 60 examples (man 33, female 27).
Therapeutic Method: 1, treatment group: adopt Tibetan medicine embodiment 1 powder of the present invention; 1.5g/ time, 3 times/d 30 days is a course for the treatment of.During treatment, regularly inquire about more than three, body weight, Signs, Od, 15d, 30d measure respectively fasting glucose record, add if desired and look into OGTT, determine with.
2, matched group: adopt diamicron 80～160mg/ time, 3 times/d 30 days is a course for the treatment of, equally treats observed and recorded with treatment group.
Clinical efficacy evaluation criteria: recovery from illness: subjective symptoms more than three disappears, fasting glucose≤7.8mmol/L; Effective: subjective symptoms more than three is improved, and fasting glucose obviously declines, but is not down to normal level; Progressive: subjective symptoms more than three takes a turn for the better, but fasting glucose is without significant change; Invalid: the state of an illness is unchanged, conscious symptom more than three even increases the weight of without taking a turn for the better.Recovery from illness adds the effective effective percentage that adds up to.
Clinical observation.The results are shown in Table 4.
The observation of curative effect of table 4 Tibetan medicine embodiment 1 powder treatment diabetes hypoglycemic activity of the present invention:
Project treatment group matched group
Number of cases (n) percentage rate (%) number of cases (n) percentage rate (%)
Fully recover 23 36.51 21 35
Effective 29 46.03 27 45
Progressive 9
14.29 9 15
Invalid 2
3.17 35
Add up to 63 100.00 60 100.00
Be treatment group effective percentage 82.54%, matched group effective percentage 80.00%.But recovery from illness refers to transference cure more than three at that time in table, fasting glucose is recovered normal level ,≤7.8mmol/L, and not source of disease is eradicated or is completely cured.
Clinical observation result shows: Tibetan medicine embodiment 1 powder treatment diabetes type II patient 63 examples of the present invention,
Effective 30 examples of recovery from illness 22 example, total effective rate 82.54%, matched group diamicron (blood sugar lowering Western medicine) is observed 60 examples equally, 20 examples of fully recovering, effective 28 examples, total effective rate be 80.00%, two group obvious to diabetics blood sugar lowering curative effect, but no significant difference (P<0.05).In two groups of therapeutic processes, all do not occur untoward reaction, clinical observation result shows: Tibetan medicine embodiment 1 powder treatment diabetes curative effect of the present invention is definite, and clinic is promoted the use of, and has good application prospect.
In the preparation of conventional oral solid formulation dosage form, the preparation of powder belongs to part operation above in other conventional oral solid formulation preparation process, the test example of powder has proved, having good effect aspect treatment diabetes, also just to have illustrated that pill, granule, capsule, the tablet in conventional oral solid formulation dosage form also has same effect; Be that the above-mentioned embodiment enumerating 1-5 has same effect.Illustrate that Tibetan medicine of the present invention has good effect aspect treatment diabetes.
Claims (5)
1. treat the Tibetan medicine of diabetes for one kind, it is characterized in that it is to be made or be made up of active component and pharmaceutically acceptable adjuvant by active component, wherein said active component is to be made up of the crude drug of following concrete weight proportion: Fructus Coriandri sativi 50～100g, seed of Herba Apii graveolentis 25～75g, Fructus Phyllanthi 25～75g, Rhizoma Polygonati 20～60g, Radix Berberidis Amurensis 20～60g, Cortex Lycii 15～45g, Rhizoma Gymnadeniae 10～30g.
2. Tibetan medicine according to claim 1, wherein said active component is to be made up of the crude drug of following concrete weight proportion: Fructus Coriandri sativi 60～90g, seed of Herba Apii graveolentis 40～60g, Fructus Phyllanthi 40～60g, Rhizoma Polygonati 32～48g, Radix Berberidis Amurensis 32～48g, Cortex Lycii 24～36g, Rhizoma Gymnadeniae 16～24g.
3. Tibetan medicine according to claim 2, wherein said active component is to be made up of the crude drug of following concrete weight: Fructus Coriandri sativi 75g, seed of Herba Apii graveolentis 50g, Fructus Phyllanthi 50g, Rhizoma Polygonati 40g, Radix Berberidis Amurensis 40g, Cortex Lycii 30g, Rhizoma Gymnadeniae 20g.
4. according to any one Tibetan medicine described in claim 1-3, it is peroral dosage form.
5. Tibetan medicine according to claim 4, it is powder, pill, granule, capsule or tablet.
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| CN103961550A (en) * | 2014-05-25 | 2014-08-06 | 青海省通天河藏药制药有限责任公司 | Preparation method of traditional Tibetan medicine for treating diabetes |
| CN105079706A (en) * | 2015-09-09 | 2015-11-25 | 白玛仁增 | Compound Tibetan medicine preparation for treating diabetes |
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| CN101708295A (en) * | 2009-12-04 | 2010-05-19 | 卢速江 | Chinese medicinal preparation for treating diabetes and preparation methods thereof |
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| CN103961550A (en) * | 2014-05-25 | 2014-08-06 | 青海省通天河藏药制药有限责任公司 | Preparation method of traditional Tibetan medicine for treating diabetes |
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Application publication date: 20140806 |