CN112451446A - Skin-tendering porcelain skin cream - Google Patents

Skin-tendering porcelain skin cream Download PDF

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Publication number
CN112451446A
CN112451446A CN202011483781.6A CN202011483781A CN112451446A CN 112451446 A CN112451446 A CN 112451446A CN 202011483781 A CN202011483781 A CN 202011483781A CN 112451446 A CN112451446 A CN 112451446A
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Prior art keywords
skin
active substance
porcelain
tendering
cream
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CN202011483781.6A
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Chinese (zh)
Inventor
张应贤
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Guangzhou Lakel Stem Cell Research Institute
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Guangzhou Lakel Stem Cell Research Institute
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Publication of CN112451446A publication Critical patent/CN112451446A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4993Derivatives containing from 2 to 10 oxyalkylene groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55Phosphorus compounds
    • A61K8/553Phospholipids, e.g. lecithin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/673Vitamin B group
    • A61K8/675Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/678Tocopherol, i.e. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/736Chitin; Chitosan; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/007Preparations for dry skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a tender porcelain skin cream which comprises the following components in percentage by mass: 0.1-3% of whitening active substance, 0.3-2% of moisturizing active substance, 0.2-0.5% of antioxidant active substance and 94.5-99.4% of matrix material. Compared with the prior art, the invention has the advantages that: by adding the moisturizing active substances, moisturizing and hydrating are performed, the water content of the skin epidermis is maintained, the plumpness of the skin is improved, new visible light is generated, and the skin color is instantly brightened through luster reflection; the whitening active substance is added to effectively prevent and improve the pigmentation of the skin and realize deep whitening.

Description

Skin-tendering porcelain skin cream
Technical Field
The invention relates to the technical field of cosmetics, in particular to a skin-tendering porcelain skin cream.
Background
However, in the current society with increasingly worsened environment, the skin is easy to accelerate the internal aging of the skin and reduce the functions of skin cells due to factors such as external environment, such as ultraviolet radiation, dry and moist weather, irritant substances, allergens, environmental pollution and the like, so that the phenomena of skin wrinkles, skin aging, large skin pores, pigmentation and the like are generated. With the increase of age, the skin of a person becomes thin and loses elasticity, and subcutaneous adipose tissues supporting the skin of the person are lost under the action of gravity, so that the person loses youthful and beautiful appearance.
Smooth, fair and ruddy skin is sought by oriental women, most people use physical shielding products such as whitening and whitening powder for masking skin more than a decade ago, urban women seek more skin which is healthy from inside to outside today, and the skin state is moist, fair and young through the improvement of the whole skin state. Rejuvenation refers to rejuvenating the skin, primarily by whitening, and removing excess free radicals. Whitening skin care products are desired to be safe and effective. At present, the whitening agent with low concentration is difficult to have obvious effect when used at low concentration, and the whitening agent with high concentration is easy to cause skin irritation, so that the product has higher quality and more advanced technology.
Disclosure of Invention
The invention aims to provide a novel skin-care cosmetic which can keep moisture and moisturize by adding a moisture-keeping active substance, maintain the water content of the skin epidermal layer, improve the plumpness of the skin, generate new visible light and gloss reflection and realize instant brightening of the skin color; the whitening active substance is added, so that the pigmentation of the skin is effectively prevented and improved, and the deep whitening is realized.
The purpose of the invention is realized by the following technical scheme:
the skin-tendering porcelain skin cream comprises the following components in percentage by mass: 0.1-3% of whitening active substance, 0.3-2% of moisturizing active substance, 0.2-0.5% of antioxidant active substance and 94.5-99.4% of matrix material.
Further, the paint comprises the following components in percentage by mass: 2% of whitening active substance, 2% of moisturizing active substance, 0.35% of antioxidant active substance and 95.65% of matrix material.
Further, the paint comprises the following components in percentage by mass: 0.1% of whitening active substance, 0.3% of moisturizing active substance, 0.2% of antioxidant active substance and 99.4% of matrix material.
Further, the paint comprises the following components in percentage by mass: 3% of whitening active substance, 2% of moisturizing active substance, 0.5% of antioxidant active substance and 94.5% of matrix material.
Further, the whitening active substance is three or more of Glycyrrhiza Glabra (Glycyrrhiza Glabra) root extract, Verbascum Thapsus (Verbascum Thapsus) extract, Crystalide crystal highlight peptide, tranexamic acid and nicotinamide.
Further, the moisture-keeping active substance is a mixture of two or more of polymer sodium hyaluronate, acetyl chitosamine, rose leaf extract and wild soybean (Glycine SOJA) seed extract.
Further, the antioxidant active comprises fullerene, tocopherol and vitamin E.
Further, the matrix body comprises 10-15% of oil phase components, 81.4-83.5% of water phase components and 1-3% of additives.
Further, the oil phase component is one or a mixture of more of cetearyl alcohol, glyceryl stearate, PEG-100 stearate, C14-22 alcohol, C12-20 alkyl glucoside, dipentaerythritol hexacaprylate/hexacaprate, ethylhexyl methoxycinnamate, polydimethylsiloxane, diphenyl polydimethylsiloxane, cyclopentadimethylsiloxane, cyclohexasiloxane, caprylic/capric triglyceride; the water phase component is one or more of carbomer, glycerol, butanediol, EDTA-2 sodium and deionized water; the additive is one or more of triethanolamine, p-hydroxyacetophenone, 1, 2-hexanediol, polyacrylamide, C13-14 isoparaffin, and laureth-7.
Compared with the prior art, the invention has the advantages that:
the rose leaf extract utilizes plant extracts to protect the most important skin stem cells to delay skin aging, keep the skin young and endow the skin with unlimited vitality.
The Crystalide crystal highlight peptide comprises the following components: the skin care product comprises water, caprylic/capric triglyceride, cetyl palmitate, sorbitan stearate, polysorbate-80, hydrogenated lecithin and palmitoyl tetrapeptide, and can make the skin uniform, clear and bright by coordinating the mature differentiation of the epidermis to be glittering and translucent crystals.
The invention provides a skin-tendering porcelain skin cream which has multiple action mechanisms, visually brightens skin color, and obviously realizes the effects of tendering and beautifying skin and creating porcelain skin by matching with skin inner layer whitening. By adding the moisturizing active substances, moisturizing and hydrating are performed, the water content of the skin epidermis is maintained, the plumpness of the skin is improved, new visible light is generated, and the skin color is instantly brightened through luster reflection; the whitening active substance is added to effectively prevent and improve the pigmentation of the skin and realize deep whitening.
Detailed Description
Example 1
The skin-tendering porcelain skin cream comprises the following components in percentage by mass: 2% of whitening active substance, 2% of moisturizing active substance, 0.35% of antioxidant active substance and 95.65% of matrix material.
Example 2
The skin-tendering porcelain skin cream comprises the following components in percentage by mass: 0.1% of whitening active substance, 0.3% of moisturizing active substance, 0.2% of antioxidant active substance and 99.4% of matrix material.
Example 3
The skin-tendering porcelain skin cream comprises the following components in percentage by mass: 3% of whitening active substance, 2% of moisturizing active substance, 0.5% of antioxidant active substance and 94.5% of matrix material.
Comparative example 1
The difference from example 1 is that no moisturizing active was added.
Comparative example 2
The difference from example 1 is that no whitening active was added.
50 volunteers (20 men and 30 women) were selected from the skin-care cream prepared in examples 1 to 3 and comparative examples 1 to 2 and used for 2 weeks, 1 time each in the morning and evening, and the cream was used after the skin of the face was cleaned. The effect of the use was evaluated and shown in Table 1.
Table 1: enhancing skin color score
Figure BDA0002838413440000031
As shown in the evaluation of the subjects in Table 1, the subjects fed back the instant whitening effect, and the skin color became white after long-term use, and no allergy was observed.
Trial tests were conducted on the products prepared in examples 1-3 and comparative examples 1-2 to examine the effects.
Test objects: each experimental group selects 60 testers (male 20 and female 40) with dry facial skin and spots, the testers are tried for 1 time every day and used for 4 weeks continuously, and a testing instrument: skin melanin and heme tester (Mexameter MX 18).
The method comprises the following steps: after the test of the testee, after the testee cleans the face on the day and sits still for 30min in an environment with the room temperature of 23-25 ℃ and the relative humidity of 50-60%, the testee pays attention to the relaxation of the facial muscle group and slightly closes the eyes. The melanin precipitation of facial skin was measured by a skin melanin and heme tester (Mexameter MX18), and the measurement was repeated 3 times by a probe in the same area to be measured, and the average value was obtained. The relative temperature of the test environment is kept during measurement, the influence of light and sound interference is avoided, force is uniformly applied when the probe is used, and the applied pressure is constant. The subjects used for 1 week, 2 weeks, 3 weeks, 4 weeks before measuring the melanin status of the test area again. The measurement is finished, the data is saved, and the data is collated and analyzed as shown in table 2.
Figure BDA0002838413440000032
As can be seen from the results of the change in the skin melanin number of the tested part of the test person in table 2, the skin whitening and porcelain skin cream provided by the embodiment of the invention has whitening effect on the skin of most test persons, effectively improves skin pigmentation, reduces the skin dryness, and presents a tender and fair skin, and no irritation and allergy phenomenon of the product to the test person is found.

Claims (9)

1. The skin-tendering porcelain skin cream is characterized by comprising the following components in percentage by mass: 0.1-3% of whitening active substance, 0.3-2% of moisturizing active substance, 0.2-0.5% of antioxidant active substance and 94.5-99.4% of matrix material.
2. The skin-tendering porcelain skin cream according to claim 1, which is characterized by comprising the following components in percentage by mass: 2% of whitening active substance, 2% of moisturizing active substance, 0.35% of antioxidant active substance and 95.65% of matrix material.
3. The skin-tendering porcelain skin cream according to claim 1, which is characterized by comprising the following components in percentage by mass: 0.1% of whitening active substance, 0.3% of moisturizing active substance, 0.2% of antioxidant active substance and 99.4% of matrix material.
4. The skin-tendering porcelain skin cream according to claim 1, which is characterized by comprising the following components in percentage by mass: 3% of whitening active substance, 2% of moisturizing active substance, 0.5% of antioxidant active substance and 94.5% of matrix material.
5. The cream of any one of claims 1 to 4, wherein the whitening active is a mixture of three or more of Glycyrrhiza Glabra (Glycyrrhiza Glabra) root extract, Verbascum Thapsus (Verbascum Thapsus) extract, Crystalide crystal highlight peptide, tranexamic acid, and nicotinamide.
6. The skin-care porcelain skin cream as claimed in any one of claims 1 to 4, wherein the moisture-keeping active substance is a mixture of two or more of sodium hyaluronate, acetyl chitosamine, rose leaf extract, and wild soybean (Glycine SOJA) seed extract.
7. The skin tendering and porcelain skin cream as claimed in any one of claims 1 to 4, wherein the antioxidant active comprises fullerene, tocopherol vitamin E.
8. The skin-tendering porcelain muscle cream as claimed in any one of claims 1 to 4, wherein the matrix material comprises 10 to 15% of oil phase component, 81.4 to 83.5% of water phase component and 1 to 3% of additive.
9. The cream of claim 8, wherein the oily phase component is one or more of cetostearyl alcohol, glyceryl stearate, PEG-100 stearate, C14-22 alcohol, C12-20 alkyl glucoside, dipentaerythritol hexacaprylate/hexacaprate, ethylhexyl methoxycinnamate, dimethicone, diphenyl dimethicone, cyclopentadecyl dimethicone, cyclohexasiloxane, caprylic/capric triglyceride; the water phase component is one or more of carbomer, glycerol, butanediol, EDTA-2 sodium and deionized water; the additive is one or more of triethanolamine, p-hydroxyacetophenone, 1, 2-hexanediol, polyacrylamide, C13-14 isoparaffin, and laureth-7.
CN202011483781.6A 2020-12-16 2020-12-16 Skin-tendering porcelain skin cream Pending CN112451446A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114404359A (en) * 2022-01-28 2022-04-29 湖南伟方生命科技有限公司 Gynecological whitening and moistening nursing gel and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114404359A (en) * 2022-01-28 2022-04-29 湖南伟方生命科技有限公司 Gynecological whitening and moistening nursing gel and preparation method thereof
CN114404359B (en) * 2022-01-28 2024-04-02 湖南伟方生命科技有限公司 Gynecological whitening and moisturizing nursing gel and preparation method thereof

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Application publication date: 20210309