CN1124142C - Chinese medicine for treating cold and its preparing process - Google Patents

Chinese medicine for treating cold and its preparing process Download PDF

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Publication number
CN1124142C
CN1124142C CN 00112840 CN00112840A CN1124142C CN 1124142 C CN1124142 C CN 1124142C CN 00112840 CN00112840 CN 00112840 CN 00112840 A CN00112840 A CN 00112840A CN 1124142 C CN1124142 C CN 1124142C
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China
Prior art keywords
heat
medicine
present
chinese traditional
radix scutellariae
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Expired - Fee Related
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CN 00112840
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CN1317330A (en
Inventor
李南高
杨兆祥
普俊学
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Kunming Pharmaceutical Corp
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Kunming Pharmaceutical Corp
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Publication of CN1124142C publication Critical patent/CN1124142C/en
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Abstract

The present invention relates to a compound traditional Chinese medicine preparation for treating externally contracted wind-heat and a method for producing the medicine. The present invention has the efficiency of heat heating, toxin removal andwind-heatclearing. The preparation comprises extractives obtained by the traditional Chinese medicines of the following constituents of (weight percentage) 15 to 45% of honeysuckle flower, 15 to 30% of scutellaria, 10 to 25% of notoginseng leaf and 15 to 35% of heartleaf houttuynia herb. The present invention has good therapeutic effects on serious heat generation, slight aversion to cold, sweating, headache, nasal obstruction, thick pus nosal discharge, red swollen throat, heat pain and mouth thirst. The prescription is particularly developed for treating the externally contracted wind-heat, and has no toxic or side effect. In addition, because the used raw materials are only natural plants, and therefore, the present invention has low cost.

Description

A kind of Chinese traditional compound medicine and production method thereof for the treatment of affection due to external wind and heat
The present invention relates to a kind of oral drugs, is a kind ofly to have heat-clearing and toxic substances removing, declare the Chinese traditional compound medicine wind heat effect, the treatment affection due to external wind and heat, and the method for producing this medicine clearly specifically.
Publication number is that the Chinese patent file of CN 1179948A has been announced a kind of " antiviral antibacterial compound Chinese medicinal preparation ", and it mainly contains following composition (percentage by weight): chlorogenic acid 5-50%, baicalin 10-75%, houttuynine sodium bisulfite 0.5-15%, oleanolic acid 2.5-40%.It has heat-clearing and toxic substances removing, wide spectrum antibacterium, antifungal, effects such as antiviral, anti-inflammatory analgesic, calmness.The weak point one of said preparation is that raw materials used medicine is extract, and cost is higher; The 2nd, its prescription does not design at the treatment affection due to external wind and heat specially, and therefore the curative effect to affection due to external wind and heat is still waiting to improve.
The purpose of this invention is to provide a kind of Chinese traditional compound medicine and production method thereof for the treatment of affection due to external wind and heat, its prescription designs at affection due to external wind and heat disease specially, and to the good effect of this disease, and production cost is low.
Chinese traditional compound medicine of the present invention comprises the extract of gained the Chinese medicine (percentage by weight) from following component: Flos Lonicerae 15-45%, Radix Scutellariae 15-30%, Folium Notoginseng 10-25%, Herba Houttuyniae 15-35%.
The composition that Chinese traditional compound medicine of the present invention is further optimized is the extract of gained the Chinese medicine (percentage by weight) that comprises from following component: Flos Lonicerae 24-40%, Radix Scutellariae 17-25%, Folium Notoginseng 12-22%, Herba Houttuyniae 17-32%.Said extract is alcohol extract preferably.
The production method of Chinese traditional compound medicine of the present invention is as follows: Flos Lonicerae, Radix Scutellariae, Folium Notoginseng, Herba Houttuyniae are soaked the back decoct two to four times, preferably decoct three times, collecting decoction, filter, add ethanol after filtrate decompression concentrates and reach 60-70% to containing the alcohol amount, leave standstill after-filtration and remove precipitation, filtrate recycling ethanol also is condensed into thick paste, cold drying, pulverize.
Flos Lonicerae gas delicate fragrance in the prescription of the present invention, lightly seasoned, little hardship, heat-clearing and toxic substances removing, wind-heat dissipating is used for the warm blood fulminant dysentery, anemopyretic cold, epidemic febrile disease heating.The detoxifcation of Radix Scutellariae clearing away heat-fire, hemostasis is used for hygropyrexia, the cough due to lung-heat, hyperpyrexia is dry thirsty.Folium Notoginseng heat clearing away, detumescence, analgesic therapy analgesia can enhancing immunity, and the effect of tonification is arranged.The Herba Houttuyniae heat-clearing and toxic substances removing, the eliminating carbuncle evacuation of pus, inducing diuresis for treating stranguria syndrome, four flavor Chinese medicines be through scientific composition, has heat-clearing and toxic substances removing, declares the merit of wind heat clearly.Mainly to generate heat heavily, aversion to cold is light, has antiperspirant, headache, nasal obstruction, rhinorrhea, pharyngitis burning pain, the thirsty curative effect of xerostomia better.Clinical treatment treating cold due to wind-heat disease total effective rate 96.67%, cure rate reaches 60.7%, and therapeutic effect is very outstanding, and certain market prospect is arranged.The clinical experiment result is as follows:
Patient's situation: 150 3-15 year patient, wherein light-duty 44 examples, symptom are T37-38 ℃ of heating with watery nasal discharge, sneeze, headache, slight cough, hoarseness, pharyngalgia, pharyngeal hyperemia, antiadoncus etc. can be arranged; Medium-sized 71 examples, symptom with watery nasal discharge, sneeze, nasal obstruction, headache, can have moderate cough, hoarseness, pharyngalgia, pharyngeal hyperemia, antiadoncus, retropharyneal folliculosis for T38-39 ℃ of heating; Heavy 35 examples, symptom is T38-39 ℃ of heating, companion's general malaise, spirit is poor, inappetence, fear of cold, headache, cough and sniffle are heavier, and hoarseness, pharyngalgia, pharyngeal hyperemia, antiadoncus can be arranged, speckle shape exudate can be arranged, visible canescence herpes or ulcer on pharyngeal cavity, soft, the staphyleus mucosa on isthmus faucium portion and the tonsil.
Therapeutic scheme: oral capsule of the present invention, one of every 10kg body weight clothes, every day 3 times, 5 days each courses of treatment.
Criterion of therapeutical effect:
Recovery from illness---took medicine 24--48 hour in, temperature recovery is normal, no longer gos up, and disease disappears, and it is normal that abnormal index recovers;
Produce effects---took medicine 24--48 hour in, temperature recovery is normal, no longer gos up, and main sign is most of to disappear, and abnormal index is near normal;
Effectively---took medicine 48--72 hour in, temperature recovery is normal, no longer gos up, and main sign is most of to disappear, and abnormal index makes moderate progress;
Invalid---body temperature, symptom do not have improvement.
Therapeutic outcome:
The total example of the comparison sheet course of treatment several 1 day 2 days 3 days 150 70 (47%) 47 (31%) 33 (22%)
Typing observation of curative effect table typing example number recovery from illness produce effects enabledisable total effective rate light-duty 44 44, (100%) 000 100% is medium-sized by 71 31, (43.66%) 23, (32.3%) 15, (21.13%) 2, (2.82%) 97.18 heavy 35 16, (45.71%) 12, (34.28%) 4, (11.43%) 3, (8.57%) 91.43
The invention has the beneficial effects as follows that its prescription system is in particular the treatment affection due to external wind and heat and develops, therefore, have no side effect the good effect of affection due to external wind and heat; In addition since raw materials used be natural plants only, so cost is low.
Embodiment 1:
Extracting honeysuckle 1200g, Radix Scutellariae 880g, Folium Notoginseng 700g, Herba Houttuyniae 990g soaks the back and decocts three times, collecting decoction filters, and adds ethanol after filtrate decompression concentrates and reaches 65% to containing the alcohol amount, leave standstill after-filtration and remove precipitation, filtrate recycling ethanol also is condensed into thick paste, cold drying, pulverize, add appropriate amount of auxiliary materials, tabletting is made tablet.
Embodiment 2:
Extracting honeysuckle 1230g, Radix Scutellariae 900g, Folium Notoginseng 720g, Herba Houttuyniae 980g soaks the back and decocts three times, and collecting decoction filters, add ethanol after filtrate decompression concentrates and reach 63% to containing the alcohol amount, leave standstill after-filtration and remove precipitation, filtrate recycling ethanol also is condensed into thick paste, cold drying, pulverize, add appropriate amount of auxiliary materials, make granule, divide encapsulated.
Embodiment 3:
Extracting honeysuckle 698g, Radix Scutellariae 1150g, Folium Notoginseng 693g, Herba Houttuyniae 1309g soaks the back and decocts three times, and collecting decoction filters, add ethanol after filtrate decompression concentrates and reach 68% to containing the alcohol amount, leave standstill after-filtration and remove precipitation, filtrate recycling ethanol also is condensed into thick paste, cold drying, pulverize, add appropriate amount of auxiliary materials, make granule, divide encapsulated.
Above embodiment is only for the present invention is further illustrated, and scope of the present invention is not subjected to the limitation of illustrated embodiment.

Claims (5)

1, a kind of Chinese traditional compound medicine for the treatment of affection due to external wind and heat is characterized in that being made up of the extract of gained from the Chinese medicine (percentage by weight) of following component: Flos Lonicerae 14-45%, Radix Scutellariae 15-30%, Folium Notoginseng 10-25%, Herba Houttuyniae 15-35%.
2,, it is characterized in that forming: Flos Lonicerae 24-40%, Radix Scutellariae 17-25%, Folium Notoginseng 12-22%, Herba Houttuyniae 17-32% by the extract of gained from the Chinese medicine (percentage by weight) of following component as the said Chinese traditional compound medicine of claim 1.
3,, it is characterized in that said extract is the alcohol extraction extract as the said Chinese traditional compound medicine of claim 2.
4, as the production method of the arbitrary said Chinese traditional compound medicine of claim 1 to 3, it is characterized in that Flos Lonicerae, Radix Scutellariae, Folium Notoginseng, Herba Houttuyniae are soaked the back to be decocted two to four times, collecting decoction, filter, add ethanol after filtrate decompression concentrates and reach 60-70% to containing the alcohol amount, leave standstill after-filtration and remove precipitation, filtrate recycling ethanol also is condensed into thick paste, cold drying, pulverize.
5,, it is characterized in that Flos Lonicerae, Radix Scutellariae, Folium Notoginseng, Herba Houttuyniae are soaked the back to be decocted three times as the production method of the said Chinese traditional compound medicine of claim 4.
CN 00112840 2000-04-08 2000-04-08 Chinese medicine for treating cold and its preparing process Expired - Fee Related CN1124142C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 00112840 CN1124142C (en) 2000-04-08 2000-04-08 Chinese medicine for treating cold and its preparing process

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Application Number Priority Date Filing Date Title
CN 00112840 CN1124142C (en) 2000-04-08 2000-04-08 Chinese medicine for treating cold and its preparing process

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CN1317330A CN1317330A (en) 2001-10-17
CN1124142C true CN1124142C (en) 2003-10-15

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CN110314187A (en) * 2018-03-29 2019-10-11 北京盈科瑞创新药物研究有限公司 A kind of sucking silver-colored a kind of reed mentioned in ancient books pharmaceutical solutions and preparation method thereof

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Applicant after: Kunming Pharmaceutical Industry Group Corp., Ltd.

Applicant before: Kunming Pharmaceutical Co., Ltd.

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Free format text: CORRECT: APPLICANT; FROM: KUNMING MEDICINE STOCK CO., LTD. TO: KUNMING MEDICINE GROUP STOCK CO., LTD.

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Granted publication date: 20031015

Termination date: 20140408