CN112369492A - Gel candy capable of calming heart, soothing nerves and improving sleep and preparation method thereof - Google Patents
Gel candy capable of calming heart, soothing nerves and improving sleep and preparation method thereof Download PDFInfo
- Publication number
- CN112369492A CN112369492A CN202011060578.8A CN202011060578A CN112369492A CN 112369492 A CN112369492 A CN 112369492A CN 202011060578 A CN202011060578 A CN 202011060578A CN 112369492 A CN112369492 A CN 112369492A
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- China
- Prior art keywords
- sandwich
- gel candy
- theanine
- improving sleep
- calming heart
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- 230000001914 calming effect Effects 0.000 title claims abstract description 24
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- 238000002360 preparation method Methods 0.000 title claims description 9
- DATAGRPVKZEWHA-YFKPBYRVSA-N N(5)-ethyl-L-glutamine Chemical compound CCNC(=O)CC[C@H]([NH3+])C([O-])=O DATAGRPVKZEWHA-YFKPBYRVSA-N 0.000 claims abstract description 50
- BTCSSZJGUNDROE-UHFFFAOYSA-N gamma-aminobutyric acid Chemical compound NCCCC(O)=O BTCSSZJGUNDROE-UHFFFAOYSA-N 0.000 claims abstract description 27
- DATAGRPVKZEWHA-UHFFFAOYSA-N L-gamma-glutamyl-n-ethylamine Natural products CCNC(=O)CCC(N)C(O)=O DATAGRPVKZEWHA-UHFFFAOYSA-N 0.000 claims abstract description 21
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- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 description 1
- LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 description 1
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- 229930182488 steviol glycoside Natural products 0.000 description 1
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- OHHNJQXIOPOJSC-UHFFFAOYSA-N stevioside Natural products CC1(CCCC2(C)C3(C)CCC4(CC3(CCC12C)CC4=C)OC5OC(CO)C(O)C(O)C5OC6OC(CO)C(O)C(O)C6O)C(=O)OC7OC(CO)C(O)C(O)C7O OHHNJQXIOPOJSC-UHFFFAOYSA-N 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
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- 239000000230 xanthan gum Substances 0.000 description 1
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- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/50—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by shape, structure or physical form, e.g. products with supported structure
- A23G3/54—Composite products, e.g. layered, coated, filled
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/364—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/48—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing plants or parts thereof, e.g. fruits, seeds, extracts
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The invention discloses a gel candy for calming heart, soothing nerves and improving sleep, which comprises a sandwich and a skin wrapping the sandwich, wherein the sandwich comprises the following raw materials in percentage by weight of 100 percent: 40-80% of oil and fat, and wild jujube seed extract: 5-30%, L-theanine 5-20%, valerian: 1-20%, emulsifier: 1-8% and other functional auxiliary materials: 0-20%, and other seasoning accessories: 0.01-20%; the spina date seed extract, the L-theanine and the valerian are used as main raw materials, the L-theanine and the valerian are synergistic, and the liquorice extract, the poria cocos extract, the gamma-aminobutyric acid, the balm and the hops are used for assisting raw materials, so that the gel candy which is good in taste, good in effects of calming the heart, soothing the nerves and improving sleep, free of dependence and side effects, simple and easy to carry is prepared, and the insomnia problem of more people is solved more widely.
Description
The technical field is as follows:
the invention relates to the field of functional foods, in particular to a gel candy for calming heart, soothing nerves and improving sleep and a preparation method thereof.
Background art:
the physical strength and the mental strength of people can be recovered by sleeping, however, along with the rapid development of society, the pressure of people is increasing, the anxiety, the dysphoria and the depression caused by the pressure are gradually invisible killers in the life of people, and the insomnia is gradually a common phenomenon. The symptoms of insomnia are mainly manifested as: the time of falling asleep is long, and the falling asleep is difficult; dreaminess at night and easy wakefulness; drowsiness, anxiety, and dysphoria are likely to occur during the day. According to the epidemiological investigation of the third world sleep union, about 1 person suffers from insomnia in every 1 small 12 people worldwide, and more than 7 hundred million insomnia persons are suffered in 2020, insomnia is taken as a common physiological and psychological disease, which brings serious adverse effects to normal life and work of people, even causes serious accidents, and insomnia has become an influence on physical and mental health of human! Quality of life and efficiency of work.
Drug therapy is one of the important methods for treating insomnia. At present, western medicines for treating insomnia mainly stay in the stage of artificially synthesized sedative-hypnotic drugs, the insomnia can cause people to feel dizziness and inattention, although the sedative-hypnotic drugs can enable people to enter a sleep state, the phenomena of dizziness, hypodynamia, sleepiness, lassitude and the like still occur after the people are awake, most of the sleep drugs can aggravate the situation, and adverse reactions such as drug resistance, addiction, withdrawal and the like are generated.
The spina date seed belongs to homology of medicine and food, is ranked the first in the medicines for treating insomnia, and is a core medicine for treating insomnia by using the traditional Chinese medicine. The spina date seed has the effects of calming heart and tranquilizing mind, arresting sweating, promoting the production of body fluid and nourishing liver, is used for treating dysphoria and insomnia, palpitation and dreaminess, body deficiency and hyperhidrosis, body fluid deficiency and thirst, and is a traditional good medicine for calming and tranquilizing mind. Compared with western medicines, the active ingredients of the traditional Chinese medicine have the characteristics of multiple targets, multiple effect organs, mild and lasting effect and the like. Researches show that the active ingredients of the spina date seeds have the effects of tranquilizing, hypnotizing, resisting depression and anxiety, prolonging the slow wave sleep time of people and the like mainly by enhancing the central GABA energy system transfer function.
The most important physiological function of the theanine is to obviously increase alpha waves of the brain of a human body, so that the human body is in a relaxed and quiet state, the theanine has better sedative and tranquilization effects, and is considered as a natural sedative, and an electroencephalogram monitoring result shows that 50 mgL-theanine can promote the activity of alpha brain waves, so that the human body achieves a relaxed state, the spirit and physical fatigue are relieved, the pressure resistance is improved, and the emotion is improved.
Valerian is recorded as early as the Ming Dynasty 'Bencao gang mu', has sweet and mild nature and taste, can inhibit the autonomous activity of mice and prolong the sleep time of the mice, and has obvious sedative-hypnotic activity and sleep-improving effect. The research finds that the valerian extract has no influence on the sleep-wake cycle of insomnia mice, finds that the valerian extract has no influence on the number of wakefulness, non-rapid eye movement sleep and rapid eye movement sleep, but increases the activity of delta waves in the non-rapid eye movement sleep period, which shows that the valerian extract not only has the sleep induction effect, but also can improve the sleep quality.
The mechanism of insomnia is very complex, the causes of insomnia are various, the insomnia often appears alone or along with other diseases, different individual differences also exist, and different methods can be adopted according to different people and different causes.
The invention content is as follows:
the invention aims to provide a gel candy for calming heart, soothing nerves and improving sleep and a preparation method thereof.
The invention is realized by the following technical scheme:
the gel candy for calming heart, soothing nerves and improving sleep comprises a sandwich and a skin wrapping the sandwich, wherein the sandwich comprises the following raw materials in percentage by weight of 100 percent: 40-80% of oil and fat, and wild jujube seed extract: 5-30%, L-theanine 5-20%, valerian: 1-20%, emulsifier: 1-8% and other functional auxiliary materials: 0-20%, and other seasoning accessories: 0.01-20%; the preparation method of the spina date seed extract comprises the following steps: parching semen Ziziphi Spinosae, grinding, sieving with 80 mesh sieve, adding 10 times of water, decocting for 2-3 hr, decocting for 3 times, filtering, concentrating to obtain semen Ziziphi Spinosae extract concentrated solution, spray drying to obtain semen Ziziphi Spinosae extract powder with semen Ziziphi Spinosae saponin content not less than 2%; wherein the L-theanine is theanine derived from tea, and caffeine in tea is completely removed in the extraction process.
The emulsifier is selected from one or more of beeswax, monoglyceride and diglyceride fatty acid ester, sucrose fatty acid ester, and phospholipid.
The functional adjuvants include one or more of Glycyrrhrizae radix, Poria, Melissa officinalis, gamma-aminobutyric acid, and flos Lupuli.
The flavoring adjuvants comprise fruit and vegetable powder, essence, sugar alcohol (xylitol, erythritol, sorbitol, etc.), sour agent (malic acid, citric acid, etc.), sweetener (stevioside, mogroside, sucralose, etc.).
The outer shell glue solution comprises gelling agent, carrageenan, starch (modified and common), gellan gum and xanthan gum, the water holding agent comprises glycerol, sugar alcohol, sugar, carboxymethyl cellulose, hydroxypropyl cellulose and microcrystalline cellulose, and the other components comprise essence, pigment, sweetener, sour agent and fruit and vegetable juice.
Preferably, the sandwich comprises the following raw materials by the total weight percentage of 100 percent: 45-75% of oil and fat, and wild jujube seed extract: 10-20%, L-theanine 10-15%, valerian 5-10%, and an emulsifier: 1-3%, and other functional auxiliary materials: 0-10% of other seasoning accessories: 0.1 to 5 percent.
The preparation method of the gel candy for calming heart, soothing nerves and improving sleep comprises the following steps:
1) preparing a sandwich: preparing powder materials, carrying out superfine grinding to ensure that the particle size of the powder is less than or equal to 60 mu m, drying the powder with the moisture content of less than 4 percent, and weighing for later use; heating oil to 70-75 deg.C, adding emulsifier, stirring, dissolving, cooling to 60-65 deg.C, adding powder material, stirring, emulsifying and homogenizing;
2) preparing a sheath glue solution, pressing the filling and the sheath glue solution into gel candy, and drying to obtain the finished sandwich type gel candy.
The invention has the following beneficial effects:
the spina date seed extract, the L-theanine and the valerian are used as main raw materials, the L-theanine and the valerian are synergistic, and the liquorice extract, the poria cocos extract, the gamma-aminobutyric acid, the balm and the hops are used for assisting raw materials, so that the gel candy which is good in taste, good in effects of calming the heart, soothing the nerves and improving sleep, free of dependence and side effects, simple and easy to carry is prepared, and the insomnia problem of more people is solved more widely.
The specific implementation mode is as follows:
the following is a further description of the invention and is not intended to be limiting.
Example 1:
the gel candy for calming heart, soothing nerves and improving sleep comprises a sandwich and a rubber coating wrapping the sandwich, wherein the sandwich comprises the following raw materials in percentage by weight of 100 percent: 40% of sunflower seed oil, and a spina date seed extract: 30%, 20% of L-theanine, 7% of valerian, 1% of gamma-aminobutyric acid, and mono-diglycerol fatty acid ester: 1.99%, sucralose: 0.01 percent.
The preparation method comprises the following steps:
and (2) water extraction, namely, grinding the fried spina date seeds into powder, sieving the powder by using a sieve of 80 meshes, adding 10 times of water, decocting for 2-3h for 3 times, filtering and concentrating to obtain a spina date seed extract concentrated solution, and performing spray drying to obtain spina date seed extract powder, wherein the spina date seed saponin content of the spina date seed extract powder is more than or equal to 2 percent and is a main functional substance for assisting sleep of the spina date seeds.
Preparing a sandwich: all the powders are superfine ground to the particle size of less than or equal to 60 mu m for standby. Heating oleum Helianthi to 70-75 deg.C, adding mono-diglycerol fatty acid ester, dissolving, cooling to 60-65 deg.C, adding semen Ziziphi Spinosae extract, L-theanine, gamma-aminobutyric acid, rhizoma et radix Valerianae, and sucralose, stirring, cooling to 40-45 deg.C, homogenizing, and cooling to 30-35 deg.C.
Preparing a sheath glue solution, wherein the sheath glue solution comprises the following components: 38%, glycerol 12%, water: 38 percent, xylitol 7 percent and microcrystalline cellulose 5 percent, and the preparation method comprises the following steps: putting xylitol into water, heating to 65 deg.C, adding gelatin, stirring for dissolving for 90min, and vacuumizing to remove bubbles.
Pressing the sandwich and the sheath glue solution into gel candy, and drying to obtain the finished sandwich type gel candy.
Comparative example 1:
reference example 1, except that the spina date seed extract was not added.
The gel candy for calming heart, soothing nerves and improving sleep comprises a sandwich and a rubber coating wrapping the sandwich, wherein the sandwich comprises the following raw materials in percentage by weight of 100 percent: 70% of sunflower seed oil, 20% of L-theanine, 7% of valerian, 1% of gamma-aminobutyric acid, and mono-diglycerol fatty acid ester: 1.99%, sucralose: 0.01 percent.
Comparative example 2:
reference example 1 was made, except that L-theanine was not added.
The gel candy for calming heart, soothing nerves and improving sleep comprises a sandwich and a rubber coating wrapping the sandwich, wherein the sandwich comprises the following raw materials in percentage by weight of 100 percent: 60% of sunflower seed oil, and a spina date seed extract: 30%, valerian 7%, gamma-aminobutyric acid 1%, and mono-diglycerol fatty acid ester: 1.99%, sucralose: 0.01 percent.
Comparative example 3:
reference example 1 was repeated except that no valerian was added.
The gel candy for calming heart, soothing nerves and improving sleep comprises a sandwich and a rubber coating wrapping the sandwich, wherein the sandwich comprises the following raw materials in percentage by weight of 100 percent: 47% of sunflower seed oil, and a spina date seed extract: 30%, 20% of L-theanine, 1% of gamma-aminobutyric acid, and mono-diglycerol fatty acid ester: 1.99%, sucralose: 0.01 percent.
The 50 sleepers were found and were subjected to a sleep survey for 1 week and a questionnaire was filled out and the scores of the survey were recorded. 50 individuals were divided into 5 groups of 10 individuals each, and there was no difference in questionnaire scores for each group. Group a consumed the product of example 1, group B consumed the product of comparative example 1, group C consumed the product of comparative example 2, group D consumed the product of comparative example 3, each for 15 days, and group E was a blank control, which was questionnaire-asked for 1 week and scored. The results are as follows
As can be seen from the above table, the lack of any group of components does not shorten the time to sleep within 30min (the time to sleep longer than 30min is considered as insomnia), and the synergistic effect of the spina date seed extract, the L-theanine and the valerian has obvious improvement on the mental state of the next day.
Example 2:
the gel candy for calming heart, soothing nerves and improving sleep comprises a sandwich and a rubber coating wrapping the sandwich, wherein the sandwich comprises the following raw materials in percentage by weight of 100 percent: 80% of soybean oil, and extract of spina date seeds: 5%, 5% of L-theanine, 5% of gamma-aminobutyric acid, and mono-diglycerol fatty acid ester: 2%, melissa officinalis: 2.99%, steviol glycosides: 0.01 percent
Example 3:
the gel candy for calming heart, soothing nerves and improving sleep comprises a sandwich and a rubber coating wrapping the sandwich, wherein the sandwich comprises the following raw materials in percentage by weight of 100 percent: 50% of grape seed oil, and a wild jujube seed extract: 15%, 10% of L-theanine, 1% of gamma-aminobutyric acid, and white beeswax: 2%, xylitol: 15%, hops: 6.99%, sucralose: 0.01 percent
Example 4:
the gel candy for calming heart, soothing nerves and improving sleep comprises a sandwich and a rubber coating wrapping the sandwich, wherein the sandwich comprises the following raw materials in percentage by weight of 100 percent: 68.99% of camellia oil, and a spina date seed extract: 5%, L-theanine 5%, gamma-aminobutyric acid 20%, white beeswax: 1%, sucralose: 0.01 percent
Example 5:
the gel candy for calming heart, soothing nerves and improving sleep comprises a sandwich and a rubber coating wrapping the sandwich, wherein the sandwich comprises the following raw materials in percentage by weight of 100 percent: 40% of sunflower seed oil, and a spina date seed extract: 20%, 7% of L-theanine, 5% of gamma-aminobutyric acid, and white beeswax: 2%, sucrose fatty acid ester: 0.1%, phospholipid: 5.9%, licorice: 10%, poria cocos: 10 percent.
Claims (6)
1. The gel candy for calming heart, soothing nerves and improving sleep is characterized by comprising a sandwich and a skin wrapping the sandwich, wherein the sandwich comprises the following raw materials in percentage by weight of 100 percent: 40-80% of oil and fat, and wild jujube seed extract: 5-30%, L-theanine 5-20%, valerian: 1-20%, emulsifier: 1-8% and other functional auxiliary materials: 0-20%, and other seasoning accessories: 0.01-20%; the preparation method of the spina date seed extract comprises the following steps: parching semen Ziziphi Spinosae, grinding, sieving with 80 mesh sieve, adding 10 times of water, decocting for 2-3 hr, decocting for 3 times, filtering, concentrating to obtain semen Ziziphi Spinosae extract concentrated solution, spray drying to obtain semen Ziziphi Spinosae extract powder with semen Ziziphi Spinosae saponin content not less than 2%; wherein the L-theanine is theanine derived from tea, and caffeine in tea is completely removed in the extraction process.
2. The gel candy for calming heart, soothing nerves and improving sleep as claimed in claim 1, wherein the emulsifier is one or more selected from beeswax, mono-diglycerol fatty acid ester, sucrose fatty acid ester and phospholipid.
3. The gel candy for calming heart, soothing nerves and improving sleep as claimed in claim 1, wherein the functional auxiliary materials include one or more of licorice, poria cocos, melissa officinalis, gamma-aminobutyric acid and hops.
4. The gel candy as claimed in claim 1, wherein the seasoning ingredients include fruit and vegetable powder, essence, sugar alcohol, sour agent, and sweetener.
5. The gel candy for calming heart, soothing nerves and improving sleep as claimed in claim 1, wherein the center comprises the following raw materials by weight percentage of 100%: 45-75% of oil and fat, and wild jujube seed extract: 10-20%, L-theanine 10-15%, valerian 5-10%, and an emulsifier: 1-3%, and other functional auxiliary materials: 0-10% of other seasoning accessories: 0.1 to 5 percent.
6. A method for preparing the gel candy for calming heart, soothing nerves and improving sleep as claimed in claim 1, which is characterized by comprising the following steps:
1) preparing a sandwich: preparing powder materials, carrying out superfine grinding to ensure that the particle size of the powder is less than or equal to 60 mu m, drying the powder with the moisture content of less than 4 percent, and weighing for later use; heating oil to 70-75 deg.C, adding emulsifier, stirring, dissolving, cooling to 60-65 deg.C, adding powder material, stirring, emulsifying and homogenizing;
2) preparing a sheath glue solution, pressing the filling and the sheath glue solution into gel candy, and drying to obtain the finished sandwich type gel candy.
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113475612A (en) * | 2021-05-25 | 2021-10-08 | 电子科技大学中山学院 | Low-calorie soft candy 3D printing material with sleep-assisting function and soft candy 3D printing method |
| CN113875958A (en) * | 2021-10-25 | 2022-01-04 | 宣城柏维力生物工程有限公司 | Suction type functional sleep jelly and production process thereof |
| CN114680257A (en) * | 2022-03-10 | 2022-07-01 | 陕西新研药业有限公司 | Preparation method of plant beverage for improving sleep |
| CN114847389A (en) * | 2022-04-22 | 2022-08-05 | 北京农学院 | Whole-plant wild jujube kernel gel soft sweets and preparation method thereof |
| CN115154526A (en) * | 2022-06-27 | 2022-10-11 | 北京彩晔健康管理有限公司 | Composition for improving sleep and preparation method thereof |
| CN115700091A (en) * | 2022-11-17 | 2023-02-07 | 睿丽生命科技(江苏)有限公司 | Nerve-soothing and sleep-aiding beverage and preparation method thereof |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030059501A1 (en) * | 2000-05-03 | 2003-03-27 | Vincent Rivier | Confectionery product containing functional ingredients |
| US20080044499A1 (en) * | 2004-04-06 | 2008-02-21 | Taiyokagaku Co., Ltd. | Sleep Improvement Composition |
| CN105077477A (en) * | 2015-08-12 | 2015-11-25 | 北京晚安科技有限责任公司 | Sleeping-aid beverage |
| CN107897466A (en) * | 2017-11-09 | 2018-04-13 | 山东天地健生物工程有限公司 | A kind of antarctic krill oil interlayer type gel candy and preparation method thereof |
| CN109007200A (en) * | 2018-08-07 | 2018-12-18 | 王斌 | A kind of gel candy containing eucommia ulmoides seed oil |
| CN110050867A (en) * | 2019-04-24 | 2019-07-26 | 杭州娃哈哈科技有限公司 | A kind of interlayer type gel candy and preparation method thereof |
| CN111053143A (en) * | 2019-11-28 | 2020-04-24 | 北京美宝高科技有限责任公司 | Green and healthy sandwich gel candy rich in nutrition and preparation method thereof |
-
2020
- 2020-09-30 CN CN202011060578.8A patent/CN112369492A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030059501A1 (en) * | 2000-05-03 | 2003-03-27 | Vincent Rivier | Confectionery product containing functional ingredients |
| US20080044499A1 (en) * | 2004-04-06 | 2008-02-21 | Taiyokagaku Co., Ltd. | Sleep Improvement Composition |
| CN105077477A (en) * | 2015-08-12 | 2015-11-25 | 北京晚安科技有限责任公司 | Sleeping-aid beverage |
| CN107897466A (en) * | 2017-11-09 | 2018-04-13 | 山东天地健生物工程有限公司 | A kind of antarctic krill oil interlayer type gel candy and preparation method thereof |
| CN109007200A (en) * | 2018-08-07 | 2018-12-18 | 王斌 | A kind of gel candy containing eucommia ulmoides seed oil |
| CN110050867A (en) * | 2019-04-24 | 2019-07-26 | 杭州娃哈哈科技有限公司 | A kind of interlayer type gel candy and preparation method thereof |
| CN111053143A (en) * | 2019-11-28 | 2020-04-24 | 北京美宝高科技有限责任公司 | Green and healthy sandwich gel candy rich in nutrition and preparation method thereof |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113475612A (en) * | 2021-05-25 | 2021-10-08 | 电子科技大学中山学院 | Low-calorie soft candy 3D printing material with sleep-assisting function and soft candy 3D printing method |
| CN113875958A (en) * | 2021-10-25 | 2022-01-04 | 宣城柏维力生物工程有限公司 | Suction type functional sleep jelly and production process thereof |
| CN114680257A (en) * | 2022-03-10 | 2022-07-01 | 陕西新研药业有限公司 | Preparation method of plant beverage for improving sleep |
| CN114847389A (en) * | 2022-04-22 | 2022-08-05 | 北京农学院 | Whole-plant wild jujube kernel gel soft sweets and preparation method thereof |
| CN115154526A (en) * | 2022-06-27 | 2022-10-11 | 北京彩晔健康管理有限公司 | Composition for improving sleep and preparation method thereof |
| CN115700091A (en) * | 2022-11-17 | 2023-02-07 | 睿丽生命科技(江苏)有限公司 | Nerve-soothing and sleep-aiding beverage and preparation method thereof |
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Application publication date: 20210219 |