CN112368295B - 离子性自组装肽 - Google Patents

离子性自组装肽 Download PDF

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Publication number
CN112368295B
CN112368295B CN201980044909.8A CN201980044909A CN112368295B CN 112368295 B CN112368295 B CN 112368295B CN 201980044909 A CN201980044909 A CN 201980044909A CN 112368295 B CN112368295 B CN 112368295B
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pharmaceutical composition
self
peptide
cells
seq
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Chinese (zh)
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CN112368295A (zh
Inventor
恩·塞奥·吉尔
埃尔顿·阿列克斯
山本直毅
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3D Matrix Ltd
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3D Matrix Ltd
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Toxicology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
CN201980044909.8A 2018-07-03 2019-07-03 离子性自组装肽 Active CN112368295B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862693877P 2018-07-03 2018-07-03
US62/693,877 2018-07-03
PCT/IB2019/055661 WO2020008377A2 (en) 2018-07-03 2019-07-03 Ionic self-assembling peptides

Publications (2)

Publication Number Publication Date
CN112368295A CN112368295A (zh) 2021-02-12
CN112368295B true CN112368295B (zh) 2025-03-21

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201980044909.8A Active CN112368295B (zh) 2018-07-03 2019-07-03 离子性自组装肽

Country Status (5)

Country Link
US (3) US11617778B2 (https=)
EP (1) EP3818071A2 (https=)
JP (2) JP7442196B2 (https=)
CN (1) CN112368295B (https=)
WO (1) WO2020008377A2 (https=)

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EP3818071A2 (en) 2018-07-03 2021-05-12 3-D Matrix, Ltd. Ionic self-assembling peptides
US12383700B2 (en) 2019-06-13 2025-08-12 Hollister Incorporated Reusable urinary catheter products
EP4628107A3 (en) 2019-06-25 2025-12-17 Hollister Incorporated Reusable urinary catheter products
US20210106506A1 (en) * 2019-10-11 2021-04-15 Elc Management Llc Methods for cosmetic skin remodeling
US12390552B2 (en) * 2020-01-13 2025-08-19 Arch Biosurgery, Inc. Self-assembling peptide gel formulation and methods of use
CN111249469B (zh) * 2020-03-20 2022-03-08 临沂大学 一种能够溶酶体逃逸的肽纳米颗粒及其制备方法和应用
CN114377202B (zh) * 2021-12-16 2023-01-24 方向前 适用于软骨再生的功能化自组装miRNA/多肽复合水凝胶及其制备方法
WO2025106582A1 (en) * 2023-11-13 2025-05-22 University Of Florida Research Foundation, Incorporated Polymer assemblies for cargo delivery
WO2025240422A1 (en) * 2024-05-14 2025-11-20 University Of Florida Research Foundation, Incorporated Use of rada16 to reduce mucosal inflammation
CN119954905B (zh) * 2025-01-23 2025-11-14 遵义医科大学 纳米自组装短肽kld12-krh在药物、细胞载体和生物医学的应用

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JP5497451B2 (ja) 2007-12-05 2014-05-21 株式会社スリー・ディー・マトリックス 創傷治癒・皮膚再建材
RU2011118341A (ru) 2008-10-06 2012-11-20 3-Д Матрикс, Лтд. (Jp) Агент для окклюзии тканей
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JP6034868B2 (ja) 2011-09-02 2016-11-30 株式会社スリー・ディー・マトリックス 胸部の空気漏れ閉塞のための両親媒性ペプチド
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Also Published As

Publication number Publication date
EP3818071A2 (en) 2021-05-12
US12611439B2 (en) 2026-04-28
CN112368295A (zh) 2021-02-12
US11617778B2 (en) 2023-04-04
US20200009214A1 (en) 2020-01-09
JP7442196B2 (ja) 2024-03-04
JP2021531248A (ja) 2021-11-18
JP2024045511A (ja) 2024-04-02
JP7835455B2 (ja) 2026-03-25
WO2020008377A2 (en) 2020-01-09
US20230226142A1 (en) 2023-07-20
US20230241157A1 (en) 2023-08-03
WO2020008377A3 (en) 2020-04-09

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