CN112336640A - Broad-spectrum spherical active carbon toothpaste and preparation method thereof - Google Patents
Broad-spectrum spherical active carbon toothpaste and preparation method thereof Download PDFInfo
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- CN112336640A CN112336640A CN202011158054.2A CN202011158054A CN112336640A CN 112336640 A CN112336640 A CN 112336640A CN 202011158054 A CN202011158054 A CN 202011158054A CN 112336640 A CN112336640 A CN 112336640A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0241—Containing particulates characterized by their shape and/or structure
- A61K8/0279—Porous; Hollow
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/28—Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/41—Particular ingredients further characterized by their size
- A61K2800/413—Nanosized, i.e. having sizes below 100 nm
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Abstract
The invention discloses a broad-spectrum spherical active carbon toothpaste and a preparation method thereof, belonging to the technical field of daily chemicals. Consists of abrasive, purificant, humectant, thickener, foaming agent, sweetener, essence, deionized water and broad-spectrum spherical active carbon in the weight ratio of 1 to 0.001-0.03 to 0.5-0.8 to 0.05-0.5 to 0.06-0.1 to 0.01-0.05 to 0.005-0.01 to 0.2-0.8 to 0.15-0.99. By adding broad-spectrum spherical active carbon into the toothpaste, on one hand, the toothpaste has the function of whitening teeth by utilizing the characteristics of high strength and high sphericity, the defect of strong adhesion between the powdered active carbon toothpaste and the teeth is avoided, and the water consumption for washing and rinsing is reduced; on the other hand, the advantages of the pore size distribution of the antibacterial deodorant are larger than the molecular diameter of bacteria or viruses, so that the bacteria or viruses are extremely strongly adsorbed, and the aims of deodorization, inflammation diminishing and sterilization are fulfilled.
Description
Technical Field
The invention belongs to the technical field of daily chemicals, and particularly relates to a broad-spectrum spherical activated carbon toothpaste and a preparation method thereof.
Background
The toothpaste belongs to a dentifrice, and is a cleaning product which is commonly used in daily life and is used for protecting the oral hygiene. With the increasing attention of people on tooth whitening, inflammation diminishing, bacteria removing, caries prevention and the like, the multifunctional toothpaste is developed vigorously. Plastic beads have been used in toothpaste for polishing teeth and whitening teeth earlier and widely. Although the plastic microspheres have ideal whitening effect, the components of the plastic microspheres are mainly high molecular polymers such as polyethylene and the like, and are difficult to degrade, so that the products are definitely required to be eliminated in the international range. Bengqingyang et al (patent publication No. CN 107550742A) disclose a cosmetic microbead prepared from natural renewable resources, which, despite the problem of surface environmental pollution, only has the functions of polishing and removing cutin, has single use and has no effect on inflammation diminishing, deodorization, etc. The active carbon toothpaste popular in recent years can improve the effects of whitening, preventing bad breath, periodontitis and the like. Liu Yun Zhen (patent publication No. CN 110664629A) adds powdered activated carbon into toothpaste, although it has a certain action on oral inflammation and sterilization, its actual use effect is not ideal. The better adsorption performance of the powdered activated carbon on the surface of the tooth leads to overlong washing cycle, and a large amount of water is needed to be washed clean, thus leading to the waste of water resources. Meanwhile, the powdery activated carbon has nano-scale particles, and the particles can contact blood if entering intestines and stomach during the washing process, so that serious blood sequelae are caused. To avoid the above phenomenon, wuxing et al [ patent publication No. CN105147530A ] prepared a spherical carbon toothpaste using pitch-based spherical carbon instead of powdered activated carbon. Although the toothpaste has the whitening function, the asphalt-based spherical carbon has the pore size distribution of less than 1.5nm, most molecules such as inflammation and bacteria have the diameter of more than 10nm, so that the actual functions of deodorization, inflammation diminishing and sterilization of the asphalt-based spherical carbon are extremely low. Based on the research and analysis, the broad-spectrum spherical active carbon toothpaste with high strength and wide pore size distribution can play a role in whitening, can adsorb different inflammatory molecules in micro-sized and large-sized tissues by utilizing the unique pore size, and has important application value.
Disclosure of Invention
Aiming at the problems, the invention provides a broad-spectrum spherical active carbon toothpaste and a preparation method thereof.
The invention aims to overcome the defects of the traditional toothpaste and provides a broad-spectrum spherical active carbon toothpaste which has the functions of whitening and preventing periodontitis, gingivitis, tooth bleeding and oral odor and a preparation method thereof.
In order to achieve the purpose, the invention adopts the following technical scheme:
a broad-spectrum spherical active carbon toothpaste is prepared from abrasive, purificant, humectant, thickener, foaming agent, sweetening agent, essence, deionized water and broad-spectrum spherical active carbon at a weight ratio of 1:0.001-0.03:0.5-0.8:0.05-0.5:0.06-0.1:0.01-0.05:0.005-0.01:0.2-0.8: 0.15-0.99.
Further, the pore size distribution of the broad spectrum type spherical activated carbon is 1-3nm and 10-100 nm.
Further, the sphericity of the broad-spectrum spherical activated carbon is 95-99%; the mechanical strength is 17-30N/cm2。
Further, the raw material of the broad-spectrum spherical activated carbon is any one of phenolic resin, ion exchange resin and macroporous adsorption resin.
A preparation method of a broad-spectrum spherical active carbon toothpaste comprises the following steps:
and 2, adding the weighed materials into a high-speed stirrer for stirring to finally form the broad-spectrum spherical active carbon toothpaste.
Further, the stirring speed in the high-speed stirrer is 100-1000rpm, the stirring temperature is 20-30 ℃, the stirring time is 1-10h, and the viscosity of the broad-spectrum spherical active carbon toothpaste is 1500-2000mPa & s.
Further, the pore size distribution of the broad spectrum type spherical activated carbon is 1-3nm and 10-100 nm.
Further, the sphericity of the broad-spectrum spherical activated carbon is 95-99%; the mechanical strength is 17-30N/cm2。
Further, the most accessible pore size distribution of the broad spectrum type spherical activated carbon is 1-1.5nm and 20-50 nm.
Further, the raw material of the broad-spectrum spherical activated carbon is any one of phenolic resin, ion exchange resin and macroporous adsorption resin.
Compared with the prior art, the invention has the following advantages:
1. has whitening and skin whitening effects;
2. can effectively prevent and treat dental diseases such as periodontitis, gingivitis, tooth bleeding and the like;
3. can effectively remove peculiar smell in the oral cavity, bacteria and the like;
4. stable chemical performance and no toxic or side effect;
5. the preparation process of the toothpaste can not cause great change of the viscosity of the toothpaste in the preparation process of other formulas of the toothpaste, namely, the whole process for preparing the toothpaste can not be influenced.
Drawings
FIG. 1 is a graph showing pore size distribution of a broad spectrum type spherical activated carbon (FIG. 1a is pore size distribution of a broad spectrum type spherical activated carbon, and FIG. 1b is pore size distribution of a pitch-based spherical activated carbon);
FIG. 2 is a macroscopic view of a broad spectrum type spherical activated carbon;
FIG. 3 is the morphology of a broad spectrum type spherical activated carbon toothpaste;
FIG. 4 shows the viscosity change of toothpaste before and after adding broad-spectrum spherical activated carbon with different contents in the same raw material ratio.
Detailed Description
Example 1
Mixing abrasive 10g, purificant 0.01g, and antiseptic 5gWetting agent, 0.5g thickener, 0.6g foaming agent, 0.1g sweetener, 0.05g essence, 2g deionized water, 1.5g broad-spectrum spherical active carbon (pore size distribution: 1-2.5nm and 10-100nm [ see figure 1 ]](ii) a Sphericity: 95% [ see FIG. 2 ]](ii) a Mechanical strength: 17N/cm2) Respectively weighing, adding into high speed stirrer, stirring at 100rpm at 20 deg.C for 10 hr to obtain broad spectrum spherical active carbon toothpaste with viscosity of 1850 mPas [ see FIGS. 3 and 4 ]]. The removal rates of the traditional Chinese medicine composition on group A streptococcus, anaerobic streptococcus, staphylococcus epidermidis, neisseria, lactobacillus, spirochete and candida are respectively 42%, 43%, 48%, 46%, 54%, 51% and 62% [ see table 1 ]]。
TABLE 1 broad-spectrum type table showing the variation trend of degerming ability of spherical activated carbon
Example 2
10g of abrasive, 0.1g of purificant, 6g of humectant, 2g of thickener, 0.8g of foaming agent, 0.2g of sweetener, 0.07g of essence, 3g of deionized water and 3.33g of broad-spectrum spherical active carbon (pore diameter distribution: 1-3nm and 50-100 nm; sphericity: 96%; mechanical strength: 20N/cm)2) Respectively weighing and metering, adding the above raw materials into a high-speed stirrer, stirring at 500rpm at 25 deg.C for 5 hr to obtain broad-spectrum spherical active carbon toothpaste with viscosity of 2000 mPas. The removal rates of the compound preparation on streptococcus A, anaerobic streptococcus, staphylococcus epidermidis, neisseria, lactobacillus, spirochete and candida are respectively 55%, 59%, 57%, 67%, 70%, 58% and 68%.
Example 3
10g of abrasive, 0.2g of purificant, 7g of humectant, 4g of thickener, 0.9g of foaming agent, 0.3g of sweetener, 0.08g of essence, 5g of deionized water and 6.05g of broad-spectrum spherical active carbon (pore diameter distribution: 1-3nm and 10-100 nm; sphericity: 98%; mechanical strength: 25N/cm)2) Respectively weighing, adding the above materials into a high-speed stirrer at stirring speed of 800rpm and at 28 deg.CStirring for 3h to finally form the broad-spectrum spherical activated carbon toothpaste with the viscosity of 1680 mPas. The removal rates of the compound preparation on streptococcus A, anaerobic streptococcus, staphylococcus epidermidis, neisseria, lactobacillus, spirochete and candida are respectively 78%, 80%, 68%, 83%, 82%, 66% and 80%.
Example 4
10g of abrasive, 0.3g of purificant, 8g of humectant, 5g of thickener, 1g of foaming agent, 0.5g of sweetener, 0.1g of essence, 8g of deionized water and 9.9g of broad-spectrum spherical active carbon (pore diameter distribution: 1-1.5nm and 20-50 nm; sphericity: 99%; mechanical strength: 30N/cm)2) Respectively weighing and metering, adding the above raw materials into a high-speed stirrer, stirring at 1000rpm at 30 deg.C for 1h, and finally forming the broad-spectrum spherical active carbon toothpaste with viscosity of 1500 mPas. The removal rates of the compound preparation on streptococcus A, anaerobic streptococcus, staphylococcus epidermidis, neisseria, lactobacillus, spirochete and candida are respectively 90%, 95%, 83%, 91%, 93%, 84% and 89%.
Those skilled in the art will appreciate that the invention may be practiced without these specific details. Although illustrative embodiments of the present invention have been described above to facilitate the understanding of the present invention by those skilled in the art, it should be understood that the present invention is not limited to the scope of the embodiments, and various changes may be made apparent to those skilled in the art as long as they are within the spirit and scope of the present invention as defined and defined by the appended claims, and all matters of the invention which utilize the inventive concepts are protected.
Claims (10)
1. A broad-spectrum spherical active carbon toothpaste is characterized in that: the cleaning agent is composed of raw materials of an abrasive, a cleaning agent, a humectant, a thickening agent, a foaming agent, a sweetening agent, essence, deionized water and broad-spectrum spherical active carbon according to the weight ratio of 1:0.001-0.03:0.5-0.8:0.05-0.5:0.06-0.1:0.01-0.05:0.005-0.01:0.2-0.8: 0.15-0.99.
2. A broad spectrum toothpaste of spherical activated carbon as claimed in claim 1, wherein: the pore size distribution of the broad spectrum type spherical activated carbon is 1-3nm and 10-100 nm.
3. A broad spectrum toothpaste of spherical activated carbon as claimed in claim 1 or 2 wherein: the sphericity of the broad spectrum type spherical activated carbon is 95-99%; the mechanical strength is 17-30N/cm2。
4. A broad spectrum toothpaste of spherical activated carbon as claimed in claim 3, characterized in that: the raw material of the broad spectrum type spherical active carbon is any one of phenolic resin, ion exchange resin and macroporous adsorption resin.
5. A preparation method of broad-spectrum spherical active carbon toothpaste is characterized by comprising the following steps: the method comprises the following steps:
step 1, respectively weighing an abrasive, a purificant, a humectant, a thickening agent, a foaming agent, a sweetening agent, essence, deionized water and broad-spectrum spherical active carbon according to the weight ratio of 1:0.001-0.03:0.5-0.8:0.05-0.5:0.06-0.1:0.01-0.05:0.005-0.01:0.2-0.8: 0.15-0.99;
and 2, adding the weighed materials into a high-speed stirrer for stirring to finally form the broad-spectrum spherical active carbon toothpaste.
6. The preparation method of a broad-spectrum spherical activated carbon toothpaste as claimed in claim 5, wherein the preparation method comprises the following steps: the stirring speed in the high-speed stirrer is 100-1000rpm, the stirring temperature is 20-30 ℃, the stirring time is 1-10h, and the viscosity of the broad-spectrum spherical active carbon toothpaste is 1500-2000mPa & s.
7. The broad spectrum spherical activated carbon toothpaste according to claim 6 wherein: the pore size distribution of the broad spectrum type spherical activated carbon is 1-3nm and 10-100 nm.
8. A broad spectrum toothpaste of spherical activated carbon according to claim 7,the method is characterized in that: the sphericity of the broad spectrum type spherical activated carbon is 95-99%; the mechanical strength is 17-30N/cm2。
9. The preparation method of a broad-spectrum spherical activated carbon toothpaste as claimed in claim 8, wherein the preparation method comprises the following steps: the most accessible pore size distribution of the broad spectrum type spherical activated carbon is 1-1.5nm and 20-50 nm.
10. A broad spectrum toothpaste of spherical activated carbon as claimed in claim 9, wherein: the raw material of the broad spectrum type spherical active carbon is any one of phenolic resin, ion exchange resin and macroporous adsorption resin.
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| CN202011158054.2A CN112336640A (en) | 2020-10-26 | 2020-10-26 | Broad-spectrum spherical active carbon toothpaste and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115721570A (en) * | 2022-09-29 | 2023-03-03 | 深圳爱尔创口腔技术有限公司 | Whitening toothpaste |
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| CN1480399A (en) * | 2003-07-18 | 2004-03-10 | 中国科学院山西煤炭化学研究所 | Method for preparing spherical active cardon with base of resin |
| KR100861806B1 (en) * | 2007-10-05 | 2008-10-07 | 박득자 | Toothpaste |
| CN105147530A (en) * | 2015-08-20 | 2015-12-16 | 杭州皎洁口腔保健用品有限公司 | Toothpaste adopting spherical activated carbon and preparation method of toothpaste |
| CN106456460A (en) * | 2015-01-22 | 2017-02-22 | 株式会社Met | Scrub and method for using same |
| CN107550742A (en) * | 2017-07-27 | 2018-01-09 | 武汉华丽生物股份有限公司 | Microballon used for cosmetic and preparation method |
| CN110664629A (en) * | 2018-07-02 | 2020-01-10 | 刘从珍 | Active carbon toothpaste |
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2020
- 2020-10-26 CN CN202011158054.2A patent/CN112336640A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1480399A (en) * | 2003-07-18 | 2004-03-10 | 中国科学院山西煤炭化学研究所 | Method for preparing spherical active cardon with base of resin |
| KR100861806B1 (en) * | 2007-10-05 | 2008-10-07 | 박득자 | Toothpaste |
| CN106456460A (en) * | 2015-01-22 | 2017-02-22 | 株式会社Met | Scrub and method for using same |
| EP3248586A1 (en) * | 2015-01-22 | 2017-11-29 | Met Co., Ltd. | Scrub and method for using same |
| CN105147530A (en) * | 2015-08-20 | 2015-12-16 | 杭州皎洁口腔保健用品有限公司 | Toothpaste adopting spherical activated carbon and preparation method of toothpaste |
| CN107550742A (en) * | 2017-07-27 | 2018-01-09 | 武汉华丽生物股份有限公司 | Microballon used for cosmetic and preparation method |
| CN110664629A (en) * | 2018-07-02 | 2020-01-10 | 刘从珍 | Active carbon toothpaste |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115721570A (en) * | 2022-09-29 | 2023-03-03 | 深圳爱尔创口腔技术有限公司 | Whitening toothpaste |
| CN115721570B (en) * | 2022-09-29 | 2024-04-09 | 深圳爱尔创口腔技术有限公司 | Whitening toothpaste |
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Application publication date: 20210209 |