CN112315840A - Mussel mucin scalp repair composition, repair liquid and preparation method thereof - Google Patents
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
- A61K8/466—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfonic acid derivatives; Salts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/12—Preparations containing hair conditioners
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
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Abstract
The invention discloses a mussel mucin scalp repair composition, a repair liquid and a preparation method thereof, and relates to the technical field of daily cosmetics. The mussel mucin scalp care composition comprises mussel mucin, aloe extract, taurine, acetyl glutamine and salt. The scalp repair liquid prepared from the mussel mucin scalp repair composition can protect human scalp, has the functions of anti-allergy and repair, is simple in preparation method, can be prepared by simple mixing, and is suitable for industrial production.
Description
Technical Field
The invention relates to the technical field of daily cosmetics, in particular to a mussel mucin scalp repair composition, a repair liquid and a preparation method thereof.
Background
With the increasingly worsened living environment of human beings and the uneven quality of hair care products, many people have symptoms of scalp sensitivity, pruritus, inflammation and the like, so that hair loss caused by healthy scalp is increasingly aggravated, and the phenomenon that hair is not stored in the scalp is caused to be so much so that the old speaking is that hair is attached to the scalp. The existing anti-allergy repairing products are difficult to adhere to the scalp or the hair, so that the loss of the effective components is caused, and the action time is short. Therefore, the preparation of products which are reliable and can repair the scalp for a long time is a problem which needs to be solved at present.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provide a mussel mucin scalp anti-allergy repairing composition with excellent scalp repairing performance, a repairing liquid and a preparation method thereof.
In order to achieve the purpose, the technical scheme adopted by the invention is as follows: a mussel mucin scalp care composition comprises mussel mucin, Aloe extract, taurine, acetyl glutamine and salt.
Under the circumstances with normal saline coexistence, mussel mucin's partial hydrophobic group exposes, pass through hydrophobic interaction mutually combined with the lipid bilayer of cell membrane, make firm lasting adhesion of albumen at the cell surface, positive charge makes albumen adsorb the cell surface rapidly to promote the cell adherence through electrostatic physical action and crawl, promote the surface of a wound healing, have bacteriostatic action simultaneously, mussel mucin can form water proof adhesion effect with cell and tissue, play antioxidation, effect such as itch stopping pain. Even if the mussel mucin forms a complete membrane, the mussel mucin still has good water vapor and air permeability, and meets the requirement of skin wound healing. The invention achieves the aims of sterilization, inflammation diminishing and itching relieving through the firm adhesion of mussel mucin on the scalp, repairs the scalp, makes the scalp healthy and promotes the hair growth.
The aloe extract has natural moisturizing and water-locking effects, can form a smooth moisture absorption film on the skin surface, improves the softness of the formula without increasing the viscosity, and has a soothing effect due to the rich polysaccharide. In addition, the aloe has the functions of diminishing inflammation and healing wounds, contains biological enzymes, has the functions of diminishing inflammation and sterilizing by slowly hydrolyzing with the skin, and can act with collagen in the horny layer under the action of amino acid to heal the wounds.
Taurine has antioxidant effect, is helpful for synthesis of cysteine in vivo, has effects of nourishing skin, enhancing activity of cortical cells, inhibiting skin allergy, and relieving inflammation.
Aceglutamide is a skin conditioner, has a moisturizing effect, can participate in protein and carbohydrate metabolism, and can repair cells.
The applicant of the invention prepares the mussel mucin scalp care composition with good anti-allergy and anti-inflammatory effects by compounding the 5 materials and selecting the proportion of the materials, and the 5 materials interact with each other, so that the scalp care effect can be obviously improved, and the mussel mucin scalp care composition can act on the scalp for a long time.
Preferably, the mussel mucin scalp care composition comprises the following ingredients in parts by weight: mussel mucin 0.3-1 parts, aloe extract 3-5 parts, taurine 0.03-0.1 part, acetyl glutamine 0.1-1 part and salt 0.5-1 part.
Preferably, the mussel mucin scalp care composition comprises the following ingredients in parts by weight: mussel mucin 0.5-0.8 parts, aloe extract 3.5-4.5 parts, taurine 0.05-0.09 part, acetyl glutamine 0.3-0.7 part and salt 0.6-0.9 part.
Preferably, the mussel mucin scalp care composition comprises the following ingredients in parts by weight: mussel mucin 0.6 parts, aloe extract 4 parts, taurine 0.08 parts, acetyl glutamine 0.4 parts and salt 0.8 parts. The applicant of the invention proves through multiple experiments that the scalp repair composition prepared according to the proportion can be stably attached to the scalp, so that the effective ingredients can act on the scalp for a long time, and the scalp repair effect is improved.
In addition, the invention also discloses a scalp repairing liquid which comprises the mussel mucin scalp repairing composition.
Preferably, the scalp nursing liquid also comprises the following components in parts by weight: 5-15 parts of methyl propylene glycol, 0.1-0.8 part of hydroxyethyl urea, 0.03-0.1 part of allantoin, 0.5-0.8 part of hexanediol, 0.01-0.15 part of ethylhexyl glycerol and 0.01-0.15 part of phenoxyethanol.
Preferably, the scalp nursing liquid also comprises the following components in parts by weight: 8-12 parts of methyl propylene glycol, 0.3-0.6 part of hydroxyethyl urea, 0.05-0.08 part of allantoin, 0.6-0.7 part of hexanediol, 0.05-0.1 part of ethylhexyl glycerol and 0.05-0.12 part of phenoxyethanol.
Preferably, the scalp nursing liquid also comprises the following components in parts by weight: 10 parts of methyl propylene glycol, 0.5 part of hydroxyethyl urea, 0.06 part of allantoin, 0.65 part of hexanediol, 0.08 part of ethylhexyl glycerol and 0.1 part of phenoxyethanol. The applicant of the invention proves through multiple experiments that the addition amounts of the moisturizing agent and the preservative in the scalp repair liquid can also have certain influence on the final experimental effect, and the moisturizing agent and the preservative interact with the mussel mucin scalp repair composition, so that the scalp repair effect of the scalp repair liquid on the scalp can be effectively improved when the scalp repair liquid is compounded according to the proportion.
Meanwhile, the invention also discloses a preparation method of the scalp nursing liquid, which comprises the following steps:
(1) uniformly mixing phenoxyethanol, hexanediol, ethylhexyl glycerol and methyl propylene glycol to obtain a mixture A;
(2) adding acetyl glutamine, taurine, water, salt, allantoin and hydroxyethyl urea into the mixture A, and stirring until the mixture is transparent to obtain a mixture B;
(3) adding mussel mucin and aloe extract into the mixture B, and stirring uniformly to obtain the scalp nursing liquid.
Compared with the prior art, the invention has the beneficial effects that: the invention selects mussel mucin, prepares a scalp repairing composition which can be effectively adhered to the scalp through a reasonable formula, achieves good scalp anti-allergy repairing effect, does not generate other side effects, and provides a new technical means for scalp anti-allergy.
Detailed Description
To better illustrate the objects, aspects and advantages of the present invention, the present invention will be further described with reference to specific examples.
Examples 1 to 5
The formula of the mussel mucin scalp care composition according to the present invention is shown in table 1.
TABLE 1 examples 1 to 5 formulation tables (parts by weight)
Examples 6 to 10
Examples 6 to 10 of the scalp conditioner of the present invention include the scalp care compositions of examples 1 to 5, respectively, and further include the following components in parts by weight: 10 parts of methyl propylene glycol, 0.5 part of hydroxyethyl urea, 0.06 part of allantoin, 0.65 part of hexanediol, 0.08 part of ethylhexyl glycerol and 0.1 part of phenoxyethanol, and water is added to the mixture until the mixture reaches 100 parts. The scalp conditioner of examples 6 to 10 is prepared by the following method:
(1) adding phenoxyethanol, hexanediol, ethylhexylglycerin and methyl propylene glycol into an emulsifying pot, and uniformly stirring to obtain a mixture A;
(2) adding acetyl glutamine, taurine, water, salt, allantoin and hydroxyethyl urea into the mixture A, and stirring until the mixture is transparent to obtain a mixture B;
(3) adding mussel mucin and aloe extract into the mixture B, and stirring uniformly to obtain the scalp nursing liquid.
Examples 11 to 14
Examples 11 to 14 of the scalp conditioner of the present invention each include the scalp conditioner composition of example 3, and the formulations of the remaining additives are shown in table 2, and the preparation method thereof is the same as in examples 6 to 10.
TABLE 2 recipe table (parts by weight)
Comparative example 1
A scalp treatment liquid, wherein a scalp treatment composition comprises 4.45 parts of an aloe extract, 0.09 part of taurine, 0.45 part of aceglutamide and 0.9 part of salt, and the remaining ingredients and preparation method are the same as those in example 8.
Comparative example 2
A scalp care liquid, wherein a scalp care composition comprises mussel mucin 1.88 parts, taurine 0.25 part, acetylglutamine 1.25 parts and common salt 2.5 parts, and the remaining ingredients and preparation method are the same as in example 8.
Comparative example 3
A scalp care liquid, wherein a scalp care composition comprises mussel mucin 0.6 parts, aloe vera extract 4.1 parts, acetylglutamine 0.4 parts and common salt 0.8 parts, and the remaining ingredients and preparation method are the same as in example 8.
Comparative example 4
A scalp care solution, wherein a scalp care composition comprises mussel mucin 0.65 parts, aloe vera extract 4.3 parts, taurine 0.08 parts and salt 0.86 parts, and the remaining ingredients and preparation method are the same as in example 8.
Test of repair Performance
Scalp repair performance tests were performed on examples 6 to 14 and comparative examples 1 to 4, and the number of hair loss was used to characterize the quality of scalp repair performance. 78 male volunteers with alopecia at 18-35 years old are selected and randomly divided into 13 groups, 6 individuals in each group are continuously used for 3 months, and are used once every 3 days with 2mL each time, the hair loss number before use, during combing on the next day after 1 month, 2 months and 3 months is respectively recorded, the difference value between the hair loss number and the hair loss number before use is calculated, the average value of each group is calculated, and the average value is recorded in table 3.
TABLE 3 Hair loss Difference (root)
As can be seen from Table 3, compared with examples 6 to 14, the hair loss difference values of comparative examples 1 to 4 are relatively small, that is, the healing effect is poor, which shows that the mussel mucin scalp care composition consisting of 5 materials of the invention has a better scalp care effect. In addition, the difference in the number of hair loss was the largest in example 8, indicating that the scalp conditioner prepared at the formulation ratio had the optimum conditioning performance.
Finally, it should be noted that the above embodiments are only used for illustrating the technical solutions of the present invention and not for limiting the protection scope of the present invention, and although the present invention has been described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that modifications or equivalent substitutions can be made on the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention.
Claims (9)
1. A mussel mucin scalp care composition is characterized by comprising mussel mucin, aloe extract, taurine, acetyl glutamine and salt.
2. The mussel mucin scalp care composition of claim 1, comprising the following ingredients in parts by weight: mussel mucin 0.3-1 parts, aloe extract 3-5 parts, taurine 0.03-0.1 part, acetyl glutamine 0.1-1 part and salt 0.5-1 part.
3. The mussel mucin scalp care composition of claim 2, comprising the following ingredients in parts by weight: mussel mucin 0.5-0.8 parts, aloe extract 3.5-4.5 parts, taurine 0.05-0.09 part, acetyl glutamine 0.3-0.7 part and salt 0.6-0.9 part.
4. The mussel mucin scalp care composition of claim 3, comprising the following ingredients in parts by weight: mussel mucin 0.6 parts, aloe extract 4 parts, taurine 0.08 parts, acetyl glutamine 0.4 parts and salt 0.8 parts.
5. A scalp care solution comprising the mussel mucin scalp care composition according to any one of claims 1 to 4.
6. The scalp conditioner according to claim 5, further comprising the following components in parts by weight: 5-15 parts of methyl propylene glycol, 0.1-0.8 part of hydroxyethyl urea, 0.03-0.1 part of allantoin, 0.5-0.8 part of hexanediol, 0.01-0.15 part of ethylhexyl glycerol and 0.01-0.15 part of phenoxyethanol.
7. The scalp conditioner according to claim 6, further comprising the following components in parts by weight: 8-12 parts of methyl propylene glycol, 0.3-0.6 part of hydroxyethyl urea, 0.05-0.08 part of allantoin, 0.6-0.7 part of hexanediol, 0.05-0.1 part of ethylhexyl glycerol and 0.05-0.12 part of phenoxyethanol.
8. The scalp conditioner according to claim 7, further comprising the following components in parts by weight: 10 parts of methyl propylene glycol, 0.5 part of hydroxyethyl urea, 0.06 part of allantoin, 0.65 part of hexanediol, 0.08 part of ethylhexyl glycerol and 0.1 part of phenoxyethanol.
9. A method for preparing a scalp care solution according to any one of claims 6 to 8, comprising the steps of:
(1) uniformly mixing phenoxyethanol, hexanediol, ethylhexyl glycerol and methyl propylene glycol to obtain a mixture A;
(2) adding acetyl glutamine, taurine, water, salt, allantoin and hydroxyethyl urea into the mixture A, and stirring until the mixture is transparent to obtain a mixture B;
(3) adding mussel mucin and aloe extract into the mixture B, and stirring uniformly to obtain the scalp nursing liquid.
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| Application Number | Priority Date | Filing Date | Title |
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| CN202011317944.3A CN112315840A (en) | 2020-11-20 | 2020-11-20 | Mussel mucin scalp repair composition, repair liquid and preparation method thereof |
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| CN202011317944.3A CN112315840A (en) | 2020-11-20 | 2020-11-20 | Mussel mucin scalp repair composition, repair liquid and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114869802A (en) * | 2022-07-06 | 2022-08-09 | 美慕(北京)科技有限公司 | Mussel protein composition with hair care and dyeing assisting effects and preparation method and application thereof |
| CN116617109A (en) * | 2023-06-05 | 2023-08-22 | 广州植境生物科技有限公司 | Mussel mucin scalp repair composition and preparation method and application thereof |
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| CN105194675A (en) * | 2008-08-04 | 2015-12-30 | 波利化学公司 | Film-forming liquid formulations for drug release to hair and scalp |
| CN108348577A (en) * | 2015-07-20 | 2018-07-31 | 江阴市本特塞缪森生命科学研究院有限公司 | Sea-mussel mucin product and its application for inhibiting scytitis |
| CN109152716A (en) * | 2016-05-10 | 2019-01-04 | 高露洁-棕榄公司 | Taurine and aloe collaboration anti-irritant composition and method |
| CN109157670A (en) * | 2018-09-28 | 2019-01-08 | 常州大学 | A kind of composite antibacterial gel rubber material |
| CN111729124A (en) * | 2020-06-29 | 2020-10-02 | 华仁药业股份有限公司 | Wound dressing containing icodextrin |
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Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105194675A (en) * | 2008-08-04 | 2015-12-30 | 波利化学公司 | Film-forming liquid formulations for drug release to hair and scalp |
| CN108348577A (en) * | 2015-07-20 | 2018-07-31 | 江阴市本特塞缪森生命科学研究院有限公司 | Sea-mussel mucin product and its application for inhibiting scytitis |
| CN109152716A (en) * | 2016-05-10 | 2019-01-04 | 高露洁-棕榄公司 | Taurine and aloe collaboration anti-irritant composition and method |
| CN109157670A (en) * | 2018-09-28 | 2019-01-08 | 常州大学 | A kind of composite antibacterial gel rubber material |
| CN111729124A (en) * | 2020-06-29 | 2020-10-02 | 华仁药业股份有限公司 | Wound dressing containing icodextrin |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114869802A (en) * | 2022-07-06 | 2022-08-09 | 美慕(北京)科技有限公司 | Mussel protein composition with hair care and dyeing assisting effects and preparation method and application thereof |
| CN114869802B (en) * | 2022-07-06 | 2022-10-04 | 美慕(北京)科技有限公司 | Mussel protein composition with hair care and dyeing assisting effects and preparation method and application thereof |
| CN116617109A (en) * | 2023-06-05 | 2023-08-22 | 广州植境生物科技有限公司 | Mussel mucin scalp repair composition and preparation method and application thereof |
| CN116617109B (en) * | 2023-06-05 | 2024-02-20 | 广州植境生物科技有限公司 | Mussel mucin scalp repair composition and preparation method and application thereof |
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