CN112312918A - 促融合脂质纳米粒和制备其的方法以及其用于靶细胞特异性产生治疗蛋白和治疗与靶细胞有关的疾病、病况或障碍的用途 - Google Patents

促融合脂质纳米粒和制备其的方法以及其用于靶细胞特异性产生治疗蛋白和治疗与靶细胞有关的疾病、病况或障碍的用途 Download PDF

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CN112312918A
CN112312918A CN201980041436.6A CN201980041436A CN112312918A CN 112312918 A CN112312918 A CN 112312918A CN 201980041436 A CN201980041436 A CN 201980041436A CN 112312918 A CN112312918 A CN 112312918A
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target cell
lnp formulation
promoter
cells
cell
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马修·赖因·斯科尔茨
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OISIN BIOTECHNOLOGIES
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CN201980041436.6A 2018-04-18 2019-04-18 促融合脂质纳米粒和制备其的方法以及其用于靶细胞特异性产生治疗蛋白和治疗与靶细胞有关的疾病、病况或障碍的用途 Pending CN112312918A (zh)

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CN202511703583.9A CN121775163A (zh) 2018-04-18 2019-04-18 促融合脂质纳米粒、制备其的方法以及其用途

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US201862659676P 2018-04-18 2018-04-18
US62/659,676 2018-04-18
US201962821084P 2019-03-20 2019-03-20
US62/821,084 2019-03-20
PCT/US2019/028207 WO2019204666A1 (en) 2018-04-18 2019-04-18 Fusogenic lipid nanoparticles and methods for the manufacture and use thereof for the target cell-specific production of a therapeutic protein and for the treatment of a disease, condition, or disorder associated with a target cell

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Cited By (2)

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CN114540416A (zh) * 2022-02-18 2022-05-27 上海交通大学 一种表达载体、脂质纳米粒、抗肿瘤药物及其制备方法和用途
CN116712406A (zh) * 2023-04-23 2023-09-08 深圳复生命生物医药有限公司 一种病毒样纳米粒子核酸药物递送系统、制备方法及应用

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JP2020503390A (ja) 2017-01-09 2020-01-30 オイシン バイオテクノロジーズ， インコーポレイテッド 治療用タンパク質の標的細胞特異的な産生のため、および標的細胞に関連する疾患、状態、または障害の治療のための、膜融合性脂質ナノ粒子、ならびにその作製および使用のための方法
CN112312918A (zh) 2018-04-18 2021-02-02 奥依信生物技术公司 促融合脂质纳米粒和制备其的方法以及其用于靶细胞特异性产生治疗蛋白和治疗与靶细胞有关的疾病、病况或障碍的用途
US20220008557A1 (en) * 2018-11-14 2022-01-13 Flagship Pioneering Innovations V, Inc. Fusosome compositions for cns delivery
CN113631718A (zh) 2018-11-14 2021-11-09 旗舰先锋创新V股份有限公司 用于特定隔室货物递送的组合物和方法
CA3094859A1 (en) * 2020-10-01 2022-04-01 Entos Pharmaceuticals Inc. Proteolipid vesicles formulated with fusion associated small transmembrane proteins
WO2024036148A1 (en) * 2022-08-08 2024-02-15 A2 Biotherapeutics, Inc. Compositions and methods for treating blood cancers

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