CN1122715A - Functional oral liquor for enhancing human immunity - Google Patents

Abstract

The oral liquid uses three varieties of medical fungus of basidiomycetes as main material in addition of small amount of root of astragalus membranaceus, lycium barbarum and tuberous root of asparugus, and is made by fermentation process. The effective rate for treatment of cardiovascular and cerebrovascular diseases, insomnia and constipation is up to 84-95%. It is non-toxic and has no side-effect.

Description

A kind of functional oral liquid that improves body immunity

The present invention relates to field of health care products, particularly be a kind of be the center to improve the human immunologic function, the diseases prevention that can keep healthy can be treated the functional oral liquid of multiple disease again.

Defying age and raising immunologic function side medicine have kind more than 70 approximately at present, and as LIUWEI DIHUANG WAN, YUPINGFENG SAN, Beijing royal jelly etc., they have all played positive role on the one hand at this, but function ratio is less, and in some tonifying recipes use certain prerequisite are arranged also; High-tech content is low, the product instability, and the health care curative effect neither be felt quite pleased.Modern amynologic mechanism has disclosed the growth (after 40 years old) along with people's age, immunologic function is also along with descending and disorder, this has just quickened the weak process of body and the resistivity of disease when having reduced, and the medical treatment of the middle-aged and elderly people of Chan Shenging, health care problem have made the whole society be faced with serious challenge therefrom.

The objective of the invention is to for middle-aged and elderly people provides a kind of is the center to improve the human immunologic function, has fully natural green health care biological product---the functional oral liquid of multi-function action.

The present invention combines and the high-tech new product produced according to traditional medicine, health preserving, modern medicine and modern biosystem engineering.This functional oral liquid is a major ingredient with Ganoderma, Armillaria mellea, three kinds of medicinal fungis of Lentinus Edodes, and after fermentation engineering fermentation, it is formulated to add the Radix Astragali, Fructus Lycii, Radix Scutellariae, Radix Asparagi adjuvant again, and its contained component and proportioning (meter by weight) are as follows:

Ganoderma fermentation liquid 50-70 Radixs Astragali 1-3

Armillaria mellea fermented solution 20-30 Fructus Lyciis 1-2

Lentinus edodes fermented liquid 10-20 Radix Scutellariaes 0.5-1

Radix Asparagi 0.5-1

Oral liquid of the present invention has showed multi-function action, i.e. immunomodulating except containing multiple nutrient to the human body beneficial; Increase spleen and stomach function; The nourishing the liver and kidney function; The microcirculation improvement function; Remove free radical; Contain multiple bioactive polysaccharide simultaneously, its energy human activin immune system, and produce antitumor action indirectly.

Three kinds of medicinal fungis that use among the present invention are all protected storage administration committee agro-ecology center from Chinese microorganism strain and are introduced, and have guaranteed strain purity.A small amount of adjuvant Chinese herbal medicine is all stocked up from the pharmacy of authorized by state.

Three kinds of funguses among the present invention all belong to basidiomycetes, are respectively:

1, Ganoderma [Ganoderma Lucidum (Leyss.ex Fr.) Karst].

2, Armillaria mellea [Armillaria mellea (Vahl ex Fr) Ouel].

3, Lentinus Edodes [Lentinus edodes (berk) Sing].

Implementation method is that above-mentioned three kinds of standard medicinal fungis are chosen culture medium prescription separately, specifically sees table 1 for details, and the using liquid deep layer fermenting process is cultivated respectively, and concrete condition of culture and technical specification see table 2 for details.General fermentation PH reduces to 4-3.5, and mycelium begins to wear out, and promptly divides coagulation to occur, and supernatant becomes clear, and fragrant is arranged, and cleaning-less bacteria infection can stop fermentation.The fermentation liquid product (natural juice stock solution does not add water) that obtains is mixed by proportioning, and by the adding of the proportioning in the prescription Radix Astragali, structure Qi, Radix Scutellariae, Radix Asparagi mixed accessories juice, heating makes its dissolving mixing, filtration gets final product packing, and then through add a cover, autoclaving, quality inspection, packing handle can obtain can be oral the functional oral liquid product, concrete technological process sees Fig. 1 for details.

Advantage of the present invention and good effect:

1, the present invention has to improve the human immunologic function to be the multi-function action at center, except that containing multiple human body essential nutrients, immunomodulating, cardiovascular and cerebrovascular disease, insomnia, its effective percentage of constipation to be reached 84-95%, see table 3 for details.

2, the nutrient that contains of this product has kept the aggregate balancing and the reasonable proportioning of natural nutrition, and taking does not for a long time have the sort of side effect of some enriched nutritive yet, specifically sees table 4 for details.

3, by best of breed of the present invention, improved the intrinsic effect of various compositions, make comprehensive effect to have obtained performance to greatest extent, reasonably coordinated simultaneously " three big key elements " the most basic in the human body metabolism, i.e. sleep, diet, removing form good physiological metabolism circulation, for fundamentally improving old people's body constitution, important assurance and prerequisite is provided, has been subjected to user's welcome deeply.

4, the drug effect of this product, physics and chemistry sanitary index are clear and definite, and stable curative effect belongs to fully natural green health care biological preparation, and no side effects sees table 5 for details.

5, this product abundant raw materials, the source is easy to get, and is convenient to suitability for industrialized production, the quality assurance; Cost is low, and gain quick return, and high efficiency, input-output ratio are 1: 5, and does not have " three wastes " public hazards, and the fermentation technology maturation is convenient to go into operation, and antenatal preparation and with short production cycle is so have well " three is big " benefit and DEVELOPMENT PROSPECT.

Below in conjunction with embodiment in detail the present invention is described in detail:

Embodiment 1: formula for a product (unit: kilogram)

Ganoderma fermentation liquid 50 Radixs Astragali 3

Armillaria mellea fermented solution 30 Fructus Lyciis 2

Lentinus edodes fermented liquid 20 Radix Scutellariaes 1

Radix Asparagi 1

Implementation method is that above-mentioned three kinds of standard medicinal fungi Ganodermas, Armillaria mellea, Lentinus Edodess are chosen culture medium prescription separately, specifically sees table 1 for details, and the using liquid deep layer fermenting process is cultivated respectively, and condition of culture and technical specification see table 2 for details.General fermentation PH reduces to 4-3.5, and mycelium begins to wear out, and promptly divides coagulation to occur, and the supernatant ripple becomes clear, and fragrant is arranged, and cleaning-less bacteria infection can stop fermentation.The fermentation liquid product that obtains is mixed (natural juice stock solution does not add water) by above-mentioned prescription, and by the adding of the amount in the prescription Radix Astragali, Fructus Lycii, Radix Scutellariae, Radix Asparagi mixed accessories juice, heating makes its dissolving mixing, get final product packing with 80 mesh sieve filtration treatment, every vial 90ml that packs into, and then through add a cover, autoclaving (steam sterilization 112 ℃, 20 minutes), quality inspection, packing handle can obtain can be oral the functional oral liquid product

Embodiment 2: formula for a product (unit: kilogram)

Ganoderma fermentation liquid 60 Radixs Astragali 2

Armillaria mellea fermented solution 25 Fructus Lyciis 1

Lentinus edodes fermented liquid 15 Radix Scutellariaes 0.5

Radix Asparagi 0.5

Implementation method is with embodiment 1.

Embodiment 3: formula for a product (unit: kilogram)

Ganoderma fermentation liquid 70 Radixs Astragali 1

Armillaria mellea fermented solution 20 Fructus Lyciis 1

Lentinus edodes fermented liquid 10 Radix Scutellariaes 0.5

Radix Asparagi 0.5

Implementation method is with embodiment 1.

Three kinds of medicinal fungi fermentative medium formulas of table 1

Nomenclature of drug	Ganoderma proportioning (%)	Armillaria mellea proportioning (%)	Lentinus Edodes proportioning (%)
				Brown sugar	????2	????2	????2
Analysis for soybean powder	????1	????—	????—
				Semen Maydis powder	????1	????1	????1
Yeast powder	????0.2	????0.4	????0.4
				KH 2PO 4	????0.2	????0.1	????0.1
MgSO 4	????0.10	????0.05	????0.05
				Peptone	????—	????0.2????	????0.2
Vitamin B 1	????—	Trace	Trace

Table 2 deep layer condition of culture and technical specification

Content	Technical specification
		The bottling amount	?100—500ml/500—5000ml
Plant age	3---4 days
		Inoculum concentration	????????10—15％
The bottle swingging machine specification	Rotary
		Frequency of oscillation	90-240 commentaries on classics/min
Temperature	????????25——27℃
		Illumination	Dark
????PH	????????5——6
		The fermentation tank specification	????????50—500l
Inventory	????????30—300l
		Tank pressure	????????0.3—0.5kg/cm 2
Ventilation	????????1∶0.5—0.7v/v/min
		Mixing speed	90-180 commentaries on classics/min
Incubation time	4---7 days
		The termination index is determined	Mycelia contains 15-20% fragrant cleaning-less bacteria infection in PH6-3 left and right sides

Table 3. user profile feedback. the health therapy statistics

Title	The application number	Effective percentage %
			Improve immune function	????51	?????90.2
Cardiovascular and cerebrovascular disease	????38	?????84.2
			The insomnia	????23	?????95.6
Constipation	????21	?????85.8

Table 5. toxicity. physics and chemistry. health situation up to standard

Project	Acute toxicology is analyzed	Physico-chemical analysis	Health detects
				Content	??Lg507 ?10000mg/kg	Arsenic (mg/kg) 0.018 lead (mg/kg) 0.052 bronze medal (mg/kg) 0.3	Total number of bacteria＜10/ml coliform＜3 100ml pathogenic bacterium do not detect
Conclusion	Belong to nontoxic level	Meet modern sanitary standard	Meet food hygienic standard

Table 4 nutrient composition and content

Aminoacid (mg/100ml sample) protein 0.24g/100ml sample		All kinds of amino acid contents are mg/100ml relatively			PH etc. other			Vitamin			Trace element (mg/kg)
													Project	Content	Project	Content	Account for total amount %	Project	Content	Unit	Project	Content	Unit	Project	Content (mg/kg)
Aspartic Acid ASP	???30.06	Aminoacid	??244.81		??PH	???4.8		Vitamin A	??4.42	??ug/100ml	Ca (calcium)	????176.1
													Threonine THR	???8.79	Essential amino acids	??76.20	???31.13	Total acidity	???2.2％		Vitamin a-E	??0.11	??mg/100ml	P (phosphorus)	????818.0
Serine SER	???12.24	Branched-chain amino acid	??36.23	???15	Total sugar	???3.45	??g/100ml	Vitamin D2	??35.13	??iv/100ml	Fe (ferrum)	????5.18
													Glutamic acid GLU	???50.31	Aromatic amino acid	??11.74	???4.29	Reducing sugar	???0.88	??g/100ml	Vitamin C	??45.89	??mg/100ml	Mg (magnesium)	????219.0
Glycine GLY	???19.03				Sucrose	???2.01	??g/100ml	Vitamin B12	??0.21	??ug/100ml	Na (sodium)	????573.0
													Alanine ALA	???18.25				Starch	???0.55	??g/100ml	Vitamin B1	??0.03	??mg/100ml	K (potassium)	????1330
Cystine CYS	???1.91				Lecithin	???15.6	??mg/100ml	Vitamin B2	??0.4	??mg/100ml	B (boron)	????0.29
													Valine VAL	???10.29				Total fat	???475	??mg/100ml				Zn (zinc)	????0.91
Methionine MET	???2.30				Linoleic acid	???3.59	??mg/100ml				Cu (copper)	????0.13
													Isoleucine ILE	???10.85										Mn (manganese)	????0.67
Leucine LEU	???15.59										As (arsenic)	????0.018
													Tyrosine TYR	???3.77										Sr (strontium)	????0.05
Phenylalanine PHE	???7.97										Co (cobalt)	????0.011
													Lysine LYS	???8.83										Ni (nickel)	????0.077
Histidine HIS	???4.04										V (vitriol)	????0.018
													Tryptophan TRP	???1.96										Si (silicon)	????0.18
Arginine ARG	???11.74										Mo (molybdenum)	????0.011
													Proline PRO	???26.15										Ge (germanium)	????0.021
Taurine TAU	???0.73										Se (selenium)	????0.011
																								Li (lithium)	????0.009
											Cr (chromium)	????0.142
																								Ba (barium)	????0.67

Claims (2)

1, a kind of functional oral liquid that improves body immunity, it is characterized in that this functional oral liquid is a major ingredient with Ganoderma, Armillaria mellea, three kinds of medicinal fungis of Lentinus Edodes, after the fermentation engineering fermentation, it is formulated to add the Radix Astragali, structure Qi, Radix Scutellariae, Radix Asparagi adjuvant again, and its contained component and proportioning (meter by weight) are as follows:

Ganoderma fermentation liquid 50-70 Radixs Astragali 1-3

Armillaria mellea fermented solution 20-30 Fructus Lyciis 1-2

Lentinus edodes fermented liquid 10-20 Radix Scutellariaes 0.5-1

Radix Asparagi 0.5-1

2, the functional oral liquid of raising body immunity according to claim 1 is characterized in that the component of this functional oral liquid and proportioning (meter by weight) are as follows:

Ganoderma fermentation liquid 50 Radixs Astragali 3

Armillaria mellea fermented solution 30 Fructus Lyciis 2

Lentinus edodes fermented liquid 20 Radix Scutellariaes 1

Radix Asparagi 1