CN112219864A - Chinese herbal medicine antibacterial liquid and preparation method thereof - Google Patents
Chinese herbal medicine antibacterial liquid and preparation method thereof Download PDFInfo
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- CN112219864A CN112219864A CN202011192525.1A CN202011192525A CN112219864A CN 112219864 A CN112219864 A CN 112219864A CN 202011192525 A CN202011192525 A CN 202011192525A CN 112219864 A CN112219864 A CN 112219864A
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/08—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/08—Magnoliopsida [dicotyledons]
- A01N65/10—Apiaceae or Umbelliferae [Carrot family], e.g. parsley, caraway, dill, lovage, fennel or snakebed
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/08—Magnoliopsida [dicotyledons]
- A01N65/20—Fabaceae or Leguminosae [Pea or Legume family], e.g. pea, lentil, soybean, clover, acacia, honey locust, derris or millettia
Abstract
The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a Chinese herbal medicine antibacterial solution and a preparation method thereof, the Chinese herbal medicine antibacterial solution comprises an antibacterial auxiliary agent, a soapberry extract and water, wherein the antibacterial auxiliary agent comprises a radix angelicae pubescentis extracting solution, a coptis chinensis extracting solution, a radix sophorae flavescentis extracting solution and a honeysuckle extracting solution, and the components are respectively as follows by weight: 8-15 parts of radix angelicae pubescentis extracting solution, 8-10 parts of coptis chinensis extracting solution, 5-8 parts of radix sophorae flavescentis extracting solution and 4-8 parts of honeysuckle extracting solution, wherein the total glycosides of sapindus mukorossi are 60% in the sapindus mukorossi extract calculated according to a dry product.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a Chinese herbal medicine antibacterial liquid and a preparation method thereof.
Background
Bacteriostasis refers to the physical or chemical method of killing or inhibiting the growth and reproduction of microorganisms, and various bacteria exist in the natural environment at present, and part of the bacteria are harmful bacteria, such as: staphylococcus aureus, Escherichia coli, Candida albicans and the like, which are frequently exposed to the harmful bacteria, are highly required to be inhibited from causing diseases.
In summary, the invention solves the existing problems by designing the Chinese herbal medicine antibacterial liquid and the preparation method thereof.
Disclosure of Invention
The invention aims to provide a Chinese herbal medicine antibacterial liquid and a preparation method thereof, and aims to solve the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme:
a Chinese herbal medicine antibacterial liquid comprises an antibacterial auxiliary agent, a soapberry extract and water, wherein the antibacterial auxiliary agent comprises a radix angelicae pubescentis extracting solution, a coptis chinensis extracting solution, a radix sophorae flavescentis extracting solution and a honeysuckle extracting solution, and the components are respectively as follows by weight: 8-15 parts of radix angelicae pubescentis extract, 8-10 parts of coptis chinensis extract, 5-8 parts of radix sophorae flavescentis extract and 4-8 parts of honeysuckle extract.
Preferably, the total glycosides of sapindus mukorossi gaertn are 60% of the total glycosides of sapindus mukorossi gaertn.
Preferably, the weight ratio of the bacteriostatic auxiliary to the soapberry extract is as follows: (3: 1) - (5: 1).
Preferably, the specific steps are as follows:
s1, respectively obtaining the following components in parts by weight: respectively and sequentially adding the radix angelicae pubescentis extract, the coptis chinensis extract, the radix sophorae flavescentis extract and the honeysuckle extract into a reaction kettle, mixing, and uniformly stirring to obtain an antibacterial auxiliary agent for later use;
s2, obtaining the following components in parts by weight: soapberry extract and water for later use;
s3, heating the water prepared in the step S2 to 30-50 ℃, adding the soapberry extract while stirring, adding the bacteriostatic auxiliary obtained in the step S1 after the soapberry extract is completely added, stirring for 20-30 min to obtain a mixed solution, sieving with a 100-300-mesh sieve, and cooling to room temperature to obtain the Chinese herbal medicine bacteriostatic liquid.
Preferably, the stirring speed in S1 is 800-900 r/min, and the stirring speed in S3 is 600-700 r/min.
Preferably, the water in the S2 is purified water, and the room temperature in the S3 is 22-26 ℃.
Compared with the prior art, the invention has the beneficial effects that:
1. according to the invention, by designing the Chinese herbal medicine antibacterial liquid to contain the extracts of radix angelicae pubescentis, coptis chinensis, radix sophorae flavescentis, honeysuckle and soapberry and utilizing the medicinal effects of the traditional Chinese medicines of all the components to combine with each other, the antibacterial ratio to staphylococcus aureus, escherichia coli and candida albicans can reach 99.8%, the duration can reach 1min or more, the antibacterial effect is better and the stability is high.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments, and all other embodiments obtained by a person of ordinary skill in the art without creative efforts based on the embodiments of the present invention belong to the protection scope of the present invention.
The invention provides a technical scheme that: a Chinese herbal medicine antibacterial liquid comprises an antibacterial auxiliary agent, a soapberry extract and water, wherein the antibacterial auxiliary agent comprises a radix angelicae pubescentis extracting solution, a coptis chinensis extracting solution, a radix sophorae flavescentis extracting solution and a honeysuckle extracting solution, and the components are respectively as follows by weight: 8-15 parts of radix angelicae pubescentis extract, 8-10 parts of coptis chinensis extract, 5-8 parts of radix sophorae flavescentis extract and 4-8 parts of honeysuckle extract.
Further, the total glycosides of the sapindus mukorossi gaertn are 60% of the total glycosides of the sapindus mukorossi gaertn extract calculated on a dry basis.
Further, the weight ratio of the bacteriostatic auxiliary to the soapberry extract is as follows: (3: 1) - (5: 1).
Further, the method comprises the following specific steps:
s1, respectively obtaining the following components in parts by weight: respectively and sequentially adding the radix angelicae pubescentis extract, the coptis chinensis extract, the radix sophorae flavescentis extract and the honeysuckle extract into a reaction kettle, mixing, and uniformly stirring to obtain an antibacterial auxiliary agent for later use;
s2, obtaining the following components in parts by weight: soapberry extract and water for later use;
s3, heating the water prepared in the step S2 to 30-50 ℃, adding the soapberry extract while stirring, adding the bacteriostatic auxiliary obtained in the step S1 after the soapberry extract is completely added, stirring for 20-30 min to obtain a mixed solution, sieving with a 100-300-mesh sieve, and cooling to room temperature to obtain the Chinese herbal medicine bacteriostatic liquid.
Further, the stirring speed in S1 is 800-900 r/min, and the stirring speed in S3 is 600-700 r/min.
Further, the water in the S2 is purified water, and the room temperature in the S3 is 22-26 ℃.
Detailed description of the preferred embodiments
Example one
A Chinese herbal medicine antibacterial liquid comprises an antibacterial auxiliary agent, a soapberry extract and water, wherein the antibacterial auxiliary agent comprises a radix angelicae pubescentis extracting solution, a coptis chinensis extracting solution, a radix sophorae flavescentis extracting solution and a honeysuckle extracting solution, and the components are respectively as follows by weight: 10 parts of radix angelicae pubescentis extract, 8 parts of coptis chinensis extract, 8 parts of radix sophorae flavescentis extract and 8 parts of honeysuckle extract, wherein the weight ratio of the antibacterial auxiliary agent to the soapberry extract is as follows: 3: 1.
A preparation method of Chinese herbal medicine antibacterial liquid comprises the following steps:
(1) respectively obtaining the following components in parts by weight: mixing the radix angelicae pubescentis extract, the coptis chinensis extract, the radix sophorae flavescentis extract and the honeysuckle extract, and uniformly stirring to obtain the antibacterial auxiliary agent for later use, wherein the stirring speed is 800-900 r/min;
(2) the preparation method comprises the following steps of: the preparation method comprises the following steps of: soapberry extract (total glycosides 60%) and water for standby, wherein the water is purified water;
(3) heating the water prepared in the step (2) to 30-50 ℃, adding 60% of soapberry extract (total glycosides), stirring while adding, adding the antibacterial auxiliary obtained in the step (1) after completely adding, stirring for 20-30 min to obtain a mixed solution, sieving with a 100-300-mesh sieve, and cooling to room temperature to obtain a Chinese herbal medicine antibacterial solution, wherein the stirring speed is 600-700 r/min; the room temperature is 22-26 ℃.
Example two
A Chinese herbal medicine antibacterial liquid comprises an antibacterial auxiliary agent, a soapberry extract and water, wherein the antibacterial auxiliary agent comprises a radix angelicae pubescentis extracting solution, a coptis chinensis extracting solution, a radix sophorae flavescentis extracting solution and a honeysuckle extracting solution, and the components are respectively as follows by weight: 10 parts of radix angelicae pubescentis extract, 8 parts of coptis chinensis extract, 8 parts of radix sophorae flavescentis extract and 8 parts of honeysuckle extract, wherein the weight ratio of the antibacterial auxiliary agent to the soapberry extract is as follows: 4: 1.
A preparation method of Chinese herbal medicine antibacterial liquid comprises the following steps:
(1) respectively obtaining the following components in parts by weight: mixing the radix angelicae pubescentis extract, the coptis chinensis extract, the radix sophorae flavescentis extract and the honeysuckle extract, and uniformly stirring to obtain the antibacterial auxiliary agent for later use, wherein the stirring speed is 800-900 r/min;
(2) the preparation method comprises the following steps of: the preparation method comprises the following steps of: soapberry extract (total glycosides 60%) and water for standby, wherein the water is purified water;
(3) heating the water prepared in the step (2) to 30-50 ℃, adding 60% of soapberry extract (total glycosides), stirring while adding, adding the antibacterial auxiliary obtained in the step (1) after completely adding, stirring for 20-30 min to obtain a mixed solution, sieving with a 100-300-mesh sieve, and cooling to room temperature to obtain a Chinese herbal medicine antibacterial solution, wherein the stirring speed is 600-700 r/min; the room temperature is 22-26 ℃.
EXAMPLE III
A Chinese herbal medicine antibacterial liquid comprises an antibacterial auxiliary agent, a soapberry extract and water, wherein the antibacterial auxiliary agent comprises a radix angelicae pubescentis extracting solution, a coptis chinensis extracting solution, a radix sophorae flavescentis extracting solution and a honeysuckle extracting solution, and the components are respectively as follows by weight: 15 parts of radix angelicae pubescentis extract, 10 parts of coptis chinensis extract, 10 parts of radix sophorae flavescentis extract and 6 parts of honeysuckle extract, wherein the weight ratio of the antibacterial auxiliary agent to the soapberry extract is as follows: 5: 1.
A preparation method of Chinese herbal medicine antibacterial liquid comprises the following steps:
(1) respectively obtaining the following components in parts by weight: mixing the radix angelicae pubescentis extract, the coptis chinensis extract, the radix sophorae flavescentis extract and the honeysuckle extract, and uniformly stirring to obtain the antibacterial auxiliary agent for later use, wherein the stirring speed is 800-900 r/min;
(2) the preparation method comprises the following steps of: the preparation method comprises the following steps of: soapberry extract (total glycosides 60%) and water for standby, wherein the water is purified water;
(3) heating the water prepared in the step (2) to 30-50 ℃, adding 60% of soapberry extract (total glycosides), stirring while adding, adding the antibacterial auxiliary obtained in the step (1) after completely adding, stirring for 20-30 min to obtain a mixed solution, sieving with a 100-300-mesh sieve, and cooling to room temperature to obtain a Chinese herbal medicine antibacterial solution, wherein the stirring speed is 600-700 r/min; the room temperature is 22-26 ℃.
The bacteriostatic rate experiments of the Chinese herbal medicine bacteriostatic solutions prepared in the first, second and third examples are respectively carried out, and the results are as follows:
test bacteria: staphylococcus aureus, escherichia coli, and candida albicans.
Activating strains: transferring staphylococcus aureus, escherichia coli and candida albicans stored in a refrigerator at 4 ℃ to a fresh nutrient agar slant, and culturing at 37 ℃ for about 24 hours, as shown in table 1;
the results of the bacteriostatic circle test by the filter paper method are shown in table 1:
as can be seen from Table 1, the samples prepared in the first, second and third examples have the bacteriostasis ratio of 99.8% to Staphylococcus aureus, Escherichia coli and Candida albicans for 1min or more, and have better bacteriostasis effect and high stability.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.
Claims (6)
1. A Chinese herbal medicine antibacterial liquid comprises an antibacterial auxiliary agent, a soapberry extract and water, wherein the antibacterial auxiliary agent comprises a radix angelicae pubescentis extracting solution, a coptis chinensis extracting solution, a radix sophorae flavescentis extracting solution and a honeysuckle extracting solution, and the components are respectively as follows by weight: 8-15 parts of radix angelicae pubescentis extract, 8-10 parts of coptis chinensis extract, 5-8 parts of radix sophorae flavescentis extract and 4-8 parts of honeysuckle extract.
2. The Chinese herbal medicine bacteriostatic solution according to claim 1, wherein the soapberry extract contains 60% of total saponins of soapberry calculated on a dry basis.
3. The Chinese herbal medicine bacteriostatic solution according to claim 1, wherein the weight ratio of the bacteriostatic auxiliary to the soapberry extract is as follows: (3: 1) - (5: 1).
4. The preparation method of the Chinese herbal medicine bacteriostatic liquid according to claim 1, comprising the following steps:
s1, respectively obtaining the following components in parts by weight: respectively and sequentially adding the radix angelicae pubescentis extract, the coptis chinensis extract, the radix sophorae flavescentis extract and the honeysuckle extract into a reaction kettle, mixing, and uniformly stirring to obtain an antibacterial auxiliary agent for later use;
s2, obtaining the following components in parts by weight: soapberry extract and water for later use;
s3, heating the water prepared in the step S2 to 30-50 ℃, adding the soapberry extract while stirring, adding the bacteriostatic auxiliary obtained in the step S1 after the soapberry extract is completely added, stirring for 20-30 min to obtain a mixed solution, sieving with a 100-300-mesh sieve, and cooling to room temperature to obtain the Chinese herbal medicine bacteriostatic liquid.
5. The method for preparing the Chinese herbal medicine bacteriostatic liquid according to claim 4, wherein the stirring speed in S1 is 800-900 r/min, and the stirring speed in S3 is 600-700 r/min.
6. The method for preparing the Chinese herbal medicine bacteriostatic liquid according to claim 4, wherein the water in S2 is purified water, and the room temperature in S3 is 22-26 ℃.
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| CN202011192525.1A CN112219864A (en) | 2020-10-30 | 2020-10-30 | Chinese herbal medicine antibacterial liquid and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114209753A (en) * | 2021-12-29 | 2022-03-22 | 广东宇通医药生物科技有限公司 | Chinese herbal medicine antibacterial liquid and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103347529A (en) * | 2010-12-09 | 2013-10-09 | Y&B妈妈之选有限公司 | Formulations comprising saponins and uses thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103347529A (en) * | 2010-12-09 | 2013-10-09 | Y&B妈妈之选有限公司 | Formulations comprising saponins and uses thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114209753A (en) * | 2021-12-29 | 2022-03-22 | 广东宇通医药生物科技有限公司 | Chinese herbal medicine antibacterial liquid and preparation method thereof |
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Application publication date: 20210115 |