CN112190490A - 一种含有氧气的乳液及其制备方法 - Google Patents
一种含有氧气的乳液及其制备方法 Download PDFInfo
- Publication number
- CN112190490A CN112190490A CN202010960171.4A CN202010960171A CN112190490A CN 112190490 A CN112190490 A CN 112190490A CN 202010960171 A CN202010960171 A CN 202010960171A CN 112190490 A CN112190490 A CN 112190490A
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- Prior art keywords
- oxygen
- extract
- containing emulsion
- skin
- oil
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
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Abstract
本发明公开了一种可明显改善皮肤光泽度的含有氧气的乳液及其制备方法，按重量百分比计，该乳液包含：旱金莲提取物0.1‑10％、海水仙提取物0.1‑10％、酵母提取物0.1‑10％、增稠剂0.01‑3％、多元醇0.5‑20％、透明质酸钠0.001‑0.5％、保湿剂0.01‑5％、乳化剂0.5‑5％、油脂0.1‑30％、余量的含有氧气浓度20‑1000ppm的水。本发明将富氧水、旱金莲提取物、海水仙提取物和酵母提取物优化比例添加到产品中，直接涂抹于皮肤上，由皮肤表层吸收，可以为皮肤带来更多的氧气，使细胞活性提高，长期使用皮肤变得更有光泽和弹性，充满活力。
Description
技术领域
本发明属于化妆品技术领域，具体地说，涉及一种含有氧气的乳液及其制备方法。
背景技术
氧气对于人体的生命和健康至关重要，人体没有氧气只能存活5分钟，氧气最主要的作用是产能，参与机体的各种运作。在细胞水平上，氧的供给是保证皮肤细胞产生所需的代谢能量的条件，从而保证皮肤的平衡和活力。
富氧水在化妆品中已有报道，但距离实际应用仍然存在技术障碍：
一方面，常压下氧气在纯水中的溶解度只有8ppm，富氧水需要通过专门的设备和工艺，在生产过程中加入氧的成分，使水中的含氧量达到20ppm。然而常规的富氧水生产工艺有在水中鼓入氧气，但此工艺生产的氧气不能长期稳定在水中，容易挥发。
另一方面，氧气扩散能力和溶解性较差，通过空气进入皮肤的氧气，只能存在于皮肤表面。上层皮肤分子氧的供给几乎全部来自周围的大气。血液中的氧气被可逆地结合到血红蛋白形成氧合血红蛋白。到达细胞附近时，氧从血红蛋白上分离，通过浓度梯度穿透毛细血管壁进入细胞外环境，氧随后被细胞捕获利用。上层皮肤随着深度的增加，分子氧的供给在减少，而毛细血管只存在于真皮乳头层及以下，表皮中有众多细胞处于或低于临界氧分压状态，因为不能得到足够的氧气和能量而处于休眠状态。
因此，为提升氧气在化妆品中的积极效果，不仅需要维持高浓度氧气在化妆品中的稳定性，还需要解决如何使氧气进入皮肤表皮的深层细胞中以及实现皮肤深层的氧合作用。
发明内容
针对上述问题，本发明的第一目的在于提供一种新的含有氧气的乳液，按重量百分比计，其包含：旱金莲提取物0.1-10％、海水仙提取物0.1-10％、酵母提取物0.1-10％、余量的含有氧气浓度20-1000ppm的水。
较佳的，所述含有氧气浓度20-1000ppm的水中，氧气以氧笼形水合物或微纳米气泡形式存在。
进一步的，所述含有氧气20-1000ppm的水为日本医药科学希望株式会社制造的富氧水或者国内的静态螺旋切割器制造的富氧水，优选含有氧气浓度20-100ppm更优选50ppm的富氧水。日本医药科学希望株式会社制造的富氧水中的氧气以氧笼形水合物形式存在，即使在摇晃和加热情况下氧气都稳定存在，且应用到化妆品中不会与化妆品成分发生反应。而富氧水采用静态螺旋切割器制备时，可以将气液体微纳米化切割细化，将氧气切割成微纳米量级小气泡能够稳定存在水中。
较佳的，所述含有氧气的乳液还包含：增稠剂、多元醇、透明质酸钠、保湿剂、乳化剂、油脂。
进一步的，所述含有氧气的乳液包含：增稠剂0.01-3％、多元醇0.5-20％、透明质酸钠0.001-0.5％、保湿剂0.01-5％、乳化剂0.5-5％、油脂0.1-30％。
优选的，按重量百分比计，其包含：旱金莲提取物1-5％、海水仙提取物1-5％、酵母提取物1-5％、增稠剂0.1-0.5％、多元醇1-5％、透明质酸钠0.02-0.15％、保湿剂0.5-3％、乳化剂0.5-5％、油脂2-15％、余量的含有氧气浓度20-100ppm的水。
更优选的，按重量百分比计，其包含：旱金莲提取物3-5％、海水仙提取物2-5％、酵母提取物2-5％、增稠剂0.35-0.5％、多元醇3-5％、透明质酸钠0.07-0.1％、保湿剂1-3％、乳化剂2-5％、油脂8-15％、余量的含有氧气浓度20-100ppm的水。
所述增稠剂为卡波姆、丙烯酰胺类、黄原胶、纤维素和聚丙烯酸钠中的一种或多种。优选为丙烯酰胺类，商品名为Aristoflex AVC，SIMULGEL NS。
所述多元醇为甘油、1,3-丙二醇、1,3-丁二醇、双丙甘醇、1,2-戊二醇和1,2-己二醇中的一种或多种。优选的甘油、1,3-丁二醇。
所述透明质酸钠可以是不同分子量的透明质酸钠，优选160万道尔顿分子量的透明质酸钠(HA)和1万道尔顿分子量的小分子透明质酸钠(小分子HA)。
所述保湿剂为甜菜碱、海藻糖、木糖醇、肌醇和泛醇中的一种或多种，优选为泛醇。
所述乳化剂为PEG-20甲基葡糖倍半硬脂酸酯、甘油硬脂酸酯、PEG-100硬脂酸酯、蔗糖乳化剂、聚甘油类乳化剂、氢化卵磷脂、甘油硬脂酸酯和PEG-20大豆甾醇中的的一种或多种。优选的NIKKOL NIKKOMULESE LC。
所述油脂为植物油、硅油、合成油脂和植物来源的半合成油脂中的一种或多种。优选的角鲨烷、季戊四醇四(乙基己酸)酯、大花可可树籽脂。
较佳的，所述含有氧气的乳液还包含稳定剂。
所述稳定剂为脂肪醇、防腐剂、香精、精油、抗氧化剂中的一种或多种。
所述防腐剂为辛酰羟肟酸、苯氧乙醇、对羟基苯乙酮、辛甘醇、乙基己基甘油、甘油辛酸酯、氯苯甘醚、苯甲醇、山梨酸钾、苯甲酸钠、脱氢乙酸及其钠盐、茴香酸钠和尼泊金酯类中的一种或多种，优选对羟基苯乙酮、苯氧乙醇、Spectrastat CGC-10，SpectrastatCGC-10生产商美国英狄士，由辛酰羟肟酸、甘油辛酸酯、1,3-丙二醇组成。
本发明的第二目的在于提供一种制备所述的含有氧气的乳液的方法，其特征在于，包括步骤：将含有氧气浓度为20-1000ppm的水、多元醇、透明质酸钠、增稠剂混合搅拌加热至75-80℃得到水相；将乳化剂和油脂混合搅拌加热至75-80℃得到油相，将油相加到水相中，搅拌均质至料体细腻均匀，降温至40-45℃，加入保湿剂、旱金莲提取物、海水仙提取物、酵母提取物，搅拌均匀，过滤出料，获得所述含有氧气的乳液。
本发明具有以下优点和有益效果：
本发明富氧水选用的是日本医药科学希望株式会社独家技术创造的气液混合泵，产生超级振动，形成氧笼形水合物，从而稳定溶解在水中。即使在摇晃和加热情况下氧气都稳定存在，且应用到化妆品中不会与化妆品成分发生反应，氧含量在50ppm左右。还有国内的静态螺旋切割器，可以将气液体微纳米化切割细化，将氧气切割成微纳米量级小气泡能够稳定存在水中。
本发明添加了旱金莲提取物，其富含阿拉伯半乳聚糖，可以提高细胞运氧载体——细胞球蛋白的含量，帮助血管中的氧气运送进入到毛细血管的作用，加强了皮肤深层的氧合作用，从而改善肤色暗沉等问题。
本发明添加的透明质酸钠HA，其具有良好的保湿作用，又是皮肤和其它组织中广泛存在的天然生物分子，从八十年代开始用于化妆品中，被誉为理想的天然保湿因子(natural moisturizing factor,NMF)。HA的保湿性能随空气湿度变化小，且还有清除自由基的作用。普通分子量与小分子量透明质酸钠结合在一起使用，在皮肤上形成薄膜锁水，小分子透明质酸更易渗透至角质层，使肌肤表层透亮光滑。
本发明使用NIKKOL NIKKOMULESE LC乳化剂，可以使乳液形成液晶结构，其形成的层状结构与皮肤角质层类似，可以减少经皮水分流失，保护肌肤屏障。
本发明添加了海水仙提取物，其可显著抑制黑色素生成，减少黑色素沉着；酵母提取物，生产商为法国SILAB公司，酵母源自松露酵母，具有优异的抗氧化功能，减少蛋白质和脂质的氧化。
本发明将含有氧气浓度为20～1000ppm的富氧水、旱金莲提取物、海水仙提取物和酵母提取物优化比例添加到产品中，可以明显改善皮肤光泽度。
总之，本发明使用氧含量在20ppm以上的富氧水制成的乳液，直接涂抹于皮肤上，由皮肤表层吸收，可以为皮肤表层带来更多的氧气；而旱金莲提取物富含阿拉伯半乳聚糖，可以提高细胞运氧载体——细胞球蛋白的含量，帮助血管中的氧气运送进入到毛细血管的作用，加强了皮肤深层的氧合作用，富氧水和旱金莲提取物相辅相成，为皮肤带来更多的氧气，使细胞活性提高，长期使用皮肤变得更有光泽，充满活力。再加入海水仙提取物和酵母提取物，使皮肤的光泽度得到最大的改善。
进一步实验证实，使用氧含量在20ppm以上的富氧水制成的本发明乳液，直接涂抹于皮肤上，由皮肤表层吸收，可以为皮肤带来更多的氧气，使细胞活性提高，长期使用皮肤变得更有光泽和弹性，充满活力。
本发明的含有氧气的乳液可用于但不限于脸部、眼部、颈部等部位。
具体实施方式
为了更清楚地说明本发明，下面结合优选实施例对本发明做进一步的说明。本领域技术人员应当理解，下面所具体描述的内容是说明性的而非限制性的，不应以此限制本发明的保护范围。
实施例1和对比例1-3
实施例1和对比例1～3的乳液的组成及配比如下表1所示。
表1实施例1和对比例1～3的乳液的组成及重量配比
制备方法：
将含有氧气浓度为50ppm的富氧水、甘油、丁二醇、HA、小分子HA、Aristoflex AVC、对羟基苯乙酮加入水相搅拌加热至75-80℃，将NIKKOL NIKKOMULESE LC、角鲨烷、季戊四醇四(乙基己酸)酯、大花可可树籽脂加入油相搅拌加热至75-80℃，将油相加到水相中，加入SIMULGEL NS，搅拌均质5分钟至料体细腻均匀，降温至40-45℃，加入苯氧乙醇、泛醇、旱金莲提取物、海水仙提取物、酵母提取物，搅拌均匀。检验合格，过滤出料，获得所述含有氧气的乳液。
效果例
(1)经皮氧分压测试
试验对象：选取同一地区、年龄段在25-50岁的志愿者40名，平均分为4组，每组10名，分别以实施例1及对比例1～3的乳液进行经皮氧分压测试。
试验方法：经皮测量皮肤的氧气分压(tcpO2)。测量最初皮肤参数，在1.5，3，4.5和6小时后测量处理过和未处理的皮肤参数。
应用区域：前臂内侧。
测试仪器：雷度米特TCM 4经皮监测仪。
试验结果：实施例1-对比例3的氧分压测试如下表2。
表2实施例1和对比例1～3的乳液的经皮氧分压测试结果
由表2结果可以看出，含有氧气浓度50ppm的水、旱金莲提取物的实施例1和对比例1的乳液涂抹在皮肤上，经皮氧分压增长比例高，皮肤中的含氧量高。不含氧气浓度50ppm的水、旱金莲提取物的乳液的对比例2和3经皮氧分压几乎不增长。
(2)皮肤亮度测试
试验对象：选取同一地区、年龄段在25-50岁的志愿者40名，平均分为4组，每组10名，分别实施例1及对比例1～3的乳液进行皮肤亮度测试。
检测周期：1个月、3个月
试验方法：用DELFIN SKINGLOSSMETER皮肤亮度测量仪测试皮肤的亮度。
试验结果：详见表3，实施例1的志愿者皮肤亮度改善明显，对比例3的志愿者皮肤亮度基本没有改善，对比例1和对比例2的改善度在中间值。
表3实施例1和对比例1～3的乳液的皮肤亮度测试结果
| 初始Gloss SGU | 1个月后Gloss SGU | 3个月后Gloss SGU | |
| 实施例1 | 50 | 65 | 82 |
| 对比例1 | 46 | 56 | 61 |
| 对比例2 | 48 | 56 | 60 |
| 对比例3 | 49 | 52 | 54 |
经过实施例和对比例的经皮氧分压测试、皮肤亮度测试可以看出，本发明的含有氧气的乳液配合旱金莲提取物、海水仙提取物、酵母提取物，通过使用含有氧气的乳液，皮肤的氧分压增加，含氧量提高，长期使用皮肤的光泽度得到提升，使皮肤更加健康充满活力。
以上所述仅是本发明的较佳实施例而已，并非对本发明作任何形式上的限制，虽然本发明已以较佳实施例揭露如上，然而并非用以限定本发明，任何熟悉本专利的技术人员在不脱离本发明技术方案范围内，当可利用上述提示的技术内容作出些许更动或修饰为等同变化的等效实施例，但凡是未脱离本发明技术方案的内容，依据本发明的技术实质对以上实施例所作的任何简单修改、等同变化与修饰，均仍属于本发明方案的范围内。
Claims (10)
1.一种含有氧气的乳液，其特征在于，按重量百分比计，其包含：旱金莲提取物0.1-10％、海水仙提取物0.1-10％、酵母提取物0.1-10％、余量的含有氧气浓度20-1000ppm的水。
2.如权利要求1所述的含有氧气的乳液，其特征在于，其还包含：增稠剂0.01-3％、多元醇0.5-20％、透明质酸钠0.001-0.5％、保湿剂0.01-5％、乳化剂0.5-5％、油脂0.1-30％。
3.如权利要求2所述的含有氧气的乳液，其特征在于，按重量百分比计，其包含：旱金莲提取物1-5％、海水仙提取物1-5％、酵母提取物1-5％、增稠剂0.1-0.5％、多元醇1-5％、透明质酸钠0.02-0.15％、保湿剂0.5-3％、乳化剂0.5-5％、油脂2-15％、余量的含有氧气浓度20-100ppm的水。
4.如权利要求2所述的含有氧气的乳液，其特征在于，所述增稠剂为卡波姆、丙烯酰胺类、黄原胶、纤维素和聚丙烯酸钠中的一种或多种。
5.如权利要求2所述的含有氧气的乳液，其特征在于，所述多元醇为甘油、1,3-丙二醇、1,3-丁二醇、双丙甘醇、1,2-戊二醇和1,2-己二醇中的一种或多种。
6.如权利要求2所述的含有氧气的乳液，其特征在于，所述保湿剂为甜菜碱、海藻糖、木糖醇、肌醇和泛醇中的一种或多种。
7.如权利要求2所述的含有氧气的乳液，其特征在于，所述乳化剂为PEG-20甲基葡糖倍半硬脂酸酯、甘油硬脂酸酯、PEG-100硬脂酸酯、蔗糖乳化剂、聚甘油类乳化剂、氢化卵磷脂、甘油硬脂酸酯和PEG-20大豆甾醇中的的一种或多种。
8.如权利要求2所述的含有氧气的乳液，其特征在于，所述油脂为植物油、硅油、合成油脂和植物来源的半合成油脂中的一种或多种。
9.如权利要求2所述的含有氧气的乳液，其特征在于，其还包含稳定剂，所述稳定剂为脂肪醇、防腐剂、香精、精油、抗氧化剂中的一种或多种。
10.一种制备权利要求1～9任一项所述的含有氧气的乳液的方法，其特征在于，包括步骤：将含有氧气浓度为20-1000ppm的水、多元醇、透明质酸钠、增稠剂混合搅拌加热至75-80℃得到水相；将乳化剂和油脂混合搅拌加热至75-80℃得到油相，将油相加到水相中，搅拌均质至料体细腻均匀，降温至40-45℃，加入保湿剂、旱金莲提取物、海水仙提取物、酵母提取物，搅拌均匀，过滤出料，获得所述含有氧气的乳液。
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Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006176429A (ja) * | 2004-12-22 | 2006-07-06 | Stefany Keshohin Kk | 化粧品とその製造方法 |
| CN102641223A (zh) * | 2011-02-18 | 2012-08-22 | 株式会社爱茉莉太平洋 | 用于改善肤色或增加皮肤弹性的化妆品组合物 |
| CN105726447A (zh) * | 2016-04-01 | 2016-07-06 | 广州九美仟惠生物科技有限公司 | 一种富含左旋vc雪肤因子能够改善肤色提亮光彩的面膜 |
| CN106420474A (zh) * | 2016-11-02 | 2017-02-22 | 芜湖光荣网络科技有限公司 | 一种含有植物提取物活性成分的化妆品组合物 |
| CN107714590A (zh) * | 2017-11-25 | 2018-02-23 | 广州市巧美化妆品有限公司 | 一种美白保湿复合物及其制备方法 |
| KR20180065166A (ko) * | 2016-12-07 | 2018-06-18 | 주식회사 코리아나화장품 | 바다수선화 추출물과 블루로터스 추출물을 유효성분으로 하는 피부 미백용 화장료 조성물 |
| CN110025547A (zh) * | 2019-04-24 | 2019-07-19 | 伯德创研(广州)生物科技有限公司 | 一种修复蓝光损伤的组合物、其制备方法及其应用 |
-
2020
- 2020-09-14 CN CN202010960171.4A patent/CN112190490A/zh active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006176429A (ja) * | 2004-12-22 | 2006-07-06 | Stefany Keshohin Kk | 化粧品とその製造方法 |
| CN102641223A (zh) * | 2011-02-18 | 2012-08-22 | 株式会社爱茉莉太平洋 | 用于改善肤色或增加皮肤弹性的化妆品组合物 |
| CN105726447A (zh) * | 2016-04-01 | 2016-07-06 | 广州九美仟惠生物科技有限公司 | 一种富含左旋vc雪肤因子能够改善肤色提亮光彩的面膜 |
| CN106420474A (zh) * | 2016-11-02 | 2017-02-22 | 芜湖光荣网络科技有限公司 | 一种含有植物提取物活性成分的化妆品组合物 |
| KR20180065166A (ko) * | 2016-12-07 | 2018-06-18 | 주식회사 코리아나화장품 | 바다수선화 추출물과 블루로터스 추출물을 유효성분으로 하는 피부 미백용 화장료 조성물 |
| CN107714590A (zh) * | 2017-11-25 | 2018-02-23 | 广州市巧美化妆品有限公司 | 一种美白保湿复合物及其制备方法 |
| CN110025547A (zh) * | 2019-04-24 | 2019-07-19 | 伯德创研(广州)生物科技有限公司 | 一种修复蓝光损伤的组合物、其制备方法及其应用 |
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