CN112129961A - Reactor supply device and reactor supply method - Google Patents

Reactor supply device and reactor supply method Download PDF

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Publication number
CN112129961A
CN112129961A CN202011001581.2A CN202011001581A CN112129961A CN 112129961 A CN112129961 A CN 112129961A CN 202011001581 A CN202011001581 A CN 202011001581A CN 112129961 A CN112129961 A CN 112129961A
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CN
China
Prior art keywords
reaction vessel
reaction
conveying
plate
conveying device
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202011001581.2A
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Chinese (zh)
Inventor
张少鹏
龚伟
张珥
高智诚
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Maccura Medical Electronics Co Ltd
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Maccura Medical Electronics Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Maccura Medical Electronics Co Ltd filed Critical Maccura Medical Electronics Co Ltd
Priority to CN202011001581.2A priority Critical patent/CN112129961A/en
Publication of CN112129961A publication Critical patent/CN112129961A/en
Priority to PCT/CN2021/119715 priority patent/WO2022063141A1/en
Pending legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system

Abstract

The present invention relates to a reaction vessel supply apparatus and a reaction vessel supply method, the reaction vessel supply apparatus including: the fixing frame comprises at least two mounting plates; the at least two conveying devices are movably connected with the at least two mounting plates in a one-to-one correspondence manner; each conveying device comprises a pair of oppositely arranged guide plate pieces, a feeding channel is formed between the pair of guide plate pieces, and the conveying device is used for supplying a plurality of reaction containers through the feeding channel; the controller is used for monitoring the running state of one conveying device which is currently in the working mode and is supplied to the reaction container; and when the operation state is abnormal, closing the current conveying device, and starting another conveying device in the at least two conveying devices to continuously supply the reaction containers. The invention can continuously supply to the reaction container, reduce the time for processing abnormal problems during shutdown and improve the working efficiency of the whole machine.

Description

Reactor supply device and reactor supply method
Technical Field
The present invention relates to the field of medical diagnosis technology, and in particular, to a reaction vessel supply device and a reaction vessel supply method.
Background
In the field of medical diagnosis, when a body fluid sample such as blood or urine is subjected to a detection analysis, it is necessary to load the sample and a reaction reagent together in a reaction vessel and then perform the detection. The reaction vessels need to be transported through a flow line from the steps of supplying, loading the sample and the reaction reagent, performing the detection and analysis, and recovering the waste reaction vessels, so as to realize the batch detection and analysis operation. The existing reaction vessel supply device is independently arranged, and needs to be stopped for maintenance when a fault occurs, so that the detection and analysis efficiency of the whole machine is greatly reduced.
Disclosure of Invention
The invention aims to provide a reaction container supply device and a reaction container supply method, wherein the reaction container supply device can continuously supply reaction containers and is beneficial to improving the working efficiency of the whole machine.
In one aspect, the present invention provides a reaction vessel supply apparatus comprising: the fixing frame comprises at least two mounting plates; the at least two conveying devices are movably connected with the at least two mounting plates in a one-to-one correspondence manner; each conveying device comprises a pair of oppositely arranged guide plate pieces, a feeding channel is formed between the pair of guide plate pieces, and the conveying device is used for supplying a plurality of reaction containers through the feeding channel; the controller is used for monitoring the running state of one conveying device which is currently in the working mode and is supplied to the reaction container; and when the operation state is abnormal, closing the current conveying device, and starting another conveying device in the at least two conveying devices to continuously supply the reaction containers.
According to one aspect of an embodiment of the invention, the supply channel of each conveyor device has a feed position and a discharge position along its length, and the guide plate member is provided with a first sensor corresponding to the discharge position for sending a first signal to the controller when a reaction vessel reaches the discharge position and a second signal when a reaction vessel is removed.
According to an aspect of the embodiment of the present invention, the controller is further configured to count the number of times of the first signal sent by the first sensor of the transport apparatus currently in the operation mode, and determine that the current operation state of the transport apparatus is abnormal when the number of times of the first signal is equal to the supply threshold value of the reaction container.
According to an aspect of the embodiment of the present invention, the controller is further configured to determine that the current operation state of the conveying device is abnormal when the first signal or the second signal sent by the first sensor of the conveying device currently in the operation mode is not received within a predetermined time.
According to an aspect of the embodiment of the present invention, the fixing frame further includes a bottom plate, the bottom plate is used for supporting at least two conveying devices, a first magnetic member is disposed at one end of the bottom plate corresponding to the supply channel, a second magnetic member and a second sensor are disposed on the guide plate, and after the conveying devices move to a predetermined position along the mounting plate, the first magnetic member and the second magnetic member are attracted together and trigger the second sensor to send a third signal to the controller.
According to one aspect of the embodiment of the invention, a fixing piece is further arranged at one end of the bottom plate corresponding to the supply channel, a positioning pin is arranged on the fixing piece, a pin hole matched with the positioning pin is correspondingly arranged on the guide plate piece, and the positioning pin extends into the pin hole after the conveying device moves to a preset position along the mounting plate.
According to an aspect of an embodiment of the present invention, each of the transport devices includes: the supporting plate is movably connected with the mounting plate, and the pair of guide plates are fixedly connected with the supporting plate; the turntable is rotatably connected with the supporting plate and comprises a rotating shaft and a pair of disc bodies which are coaxially connected with the rotating shaft and are arranged at intervals; one end of the conveying belt is wound on the rotating shaft between the pair of disc bodies, a plurality of reaction containers which are sequentially arranged are arranged on the conveying belt along the length direction of the conveying belt, and the reaction containers are positioned on one side of the conveying belt, which is far away from the rotating shaft; and the rotating wheel assembly is connected with the supporting plate, is arranged between the rotating disc and the guide plate, and is wound at the other end of the conveying belt for guiding the reaction containers on the conveying belt into the supply channel.
According to an aspect of an embodiment of the present invention, a wheel assembly includes: the driving motor is electrically connected with the controller and is rotatably connected with the supporting plate; the driving rotating wheel is coaxially connected with an output shaft of the driving motor, an annular groove is formed in the driving rotating wheel, and the other end of the conveying belt is wound on the annular groove; the first guide wheel and the second guide wheel are respectively positioned between the rotating disc and the driving rotating wheel and are in friction contact with the conveying belt, the first guide wheel is arranged close to the rotating disc and used for guiding the conveying belt into the supply channel, and the second guide wheel is positioned on one side, far away from the rotating disc, of the first guide wheel and positioned above the supply channel and used for separating the reaction container from the conveying belt.
According to one aspect of the embodiment of the present invention, a first center connecting line between the center axis of the first guide wheel and the center axis of the second guide wheel is L1, a second center connecting line between the center axis of the second guide wheel and the center axis of the driving pulley is L2, and an included angle θ between the first center connecting line L1 and the second center connecting line L2 is greater than or equal to 90 °.
According to an aspect of the embodiment of the present invention, the reaction vessel has oppositely disposed ears, and the ears are connected to the conveyor belt, and each of the guide plate members is provided with an inwardly recessed groove on a side thereof facing the feeding path; the width dimension d1 between the oppositely disposed ears is greater than the width dimension d2 of the conveyor belt and less than the distance d3 between the pair of grooves.
According to an aspect of the embodiment of the present invention, the reaction vessel supply device further includes a cap assembly including a cap plate covering the supply passage between the second guide wheel and the discharge position, and an extension part disposed at a side of the cap plate facing the supply passage and telescopically inserted into the supply passage below the second guide wheel.
According to one aspect of the embodiment of the invention, the support plate is provided with a convex column corresponding to the rotating shaft of the turntable and a lock pin rotatably connected with the convex column, the rotating shaft is sleeved on the outer periphery side of the convex column and is pressed on one of the disc bodies through the lock pin, and an elastic piece is arranged between the other disc body and the support plate.
In another aspect, the present invention provides a reaction container supply method of the reaction container supply apparatus described above, including: acquiring running state information supplied to a reaction container by a conveying device in a working mode at present; when the running state information is abnormal, sending a stop signal to the current conveying device; another of the at least two transport devices is activated to continue feeding the reaction vessels.
The reaction container supply device and the reaction container supply method provided by the invention have the advantages that by arranging at least two conveying devices capable of being pushed and pulled to move, when one conveying device supplies an abnormal reaction container, the conveying device can be replaced by the other conveying device, so that the reaction container can be continuously supplied, the time for stopping to process the abnormal problem is reduced, and the working efficiency of the whole machine is improved. In addition, the reaction container supply device has a compact integral structure, saves space and is favorable for being arranged in the assembly line detection and analysis equipment.
Drawings
Features, advantages and technical effects of exemplary embodiments of the present invention will be described below with reference to the accompanying drawings. In the drawings, like parts are provided with like reference numerals. The figures are not drawn to scale.
FIG. 1 is a schematic perspective view of a reaction vessel supply apparatus according to an embodiment of the present invention;
FIG. 2 is a schematic side view of the reaction vessel supply apparatus shown in FIG. 1 in the direction A;
FIG. 3 is a schematic view showing a partially enlarged structure of a region D of the reaction vessel supply apparatus shown in FIG. 2;
FIG. 4 is a partially enlarged schematic structural view of a region B of the reaction vessel supply apparatus shown in FIG. 1;
FIG. 5 is a schematic view showing the structure of a transport apparatus in the reaction vessel supply apparatus shown in FIG. 1;
FIG. 6 is a schematic exploded view of the delivery device shown in FIG. 5;
FIG. 7 is a schematic view showing an assembly structure of a reaction vessel and a conveyor in the reaction vessel supplying apparatus shown in FIG. 5;
FIG. 8 is a schematic top view showing the structure of a cap assembly in the reaction vessel supplier shown in FIG. 5;
FIG. 9 is a schematic view showing a rear structure of a cap assembly in the reaction vessel supplier shown in FIG. 5;
fig. 10 is a block flow diagram of a method for supplying a reaction container according to an embodiment of the present invention.
Description of reference numerals:
1-a fixed mount; 11-a mounting plate; 111-a guide rail; 112-a slider; 12-a base plate; 121-a first magnetic member; 122-a fixing member; 123-positioning pins; c-a reaction vessel; e-ear; c1-container body; c2-fixed column; o-magnetic beads;
2-a conveying device; 20-a guide plate member; 21-a supply channel; p1-feed position; p2-discharge position; 201-a first sensor; 202-a second sensor; 203-a second magnetic member; 204-pin hole; 205-grooves; 22-a support plate; 221-convex column; 222-a detent; 223-a bending part; 23-a turntable; 231-a rotating shaft; 232-disk body; 24-a conveyor belt; 25-a rotating wheel assembly; 251-a drive motor; 252-a drive wheel; 252 a-annular groove; 253-a first guide wheel; 254-a second guide wheel; 26-an elastic member;
3-a cover assembly; 31-a cover plate; 311-blind groove; 32-an extension; 33-a toggle member; 34-hinge.
Detailed Description
Features and exemplary embodiments of various aspects of the present invention will be described in detail below. In the following detailed description, numerous specific details are set forth in order to provide a thorough understanding of the present invention. It will be apparent, however, to one skilled in the art that the present invention may be practiced without some of these specific details. The following description of the embodiments is merely intended to provide a better understanding of the present invention by illustrating examples of the present invention. In the drawings and the following description, at least some well-known structures and techniques have not been shown in detail in order to avoid unnecessarily obscuring the present invention; also, the dimensions of some of the structures may be exaggerated for clarity. Furthermore, the described features, structures, or characteristics may be combined in any suitable manner in one or more embodiments.
The following description will be given with the directional terms as they are shown in the drawings, and they are not intended to limit the specific structure of the reactor vessel supply apparatus of the present invention. In the description of the present invention, it should also be noted that, unless otherwise explicitly specified or limited, the terms "mounted" and "connected" are to be interpreted broadly, e.g., as being either fixedly connected, detachably connected, or integrally connected; can be directly connected or indirectly connected. The specific meaning of the above terms in the present invention can be understood as appropriate to those of ordinary skill in the art.
For better understanding of the present invention, the following describes in detail a reaction vessel supply apparatus and a reaction vessel supply method according to an embodiment of the present invention with reference to fig. 1 to 10.
Referring to fig. 1 to 3 together, an embodiment of the present invention provides a reactor vessel supply apparatus, including: a fixed frame 1, at least two conveying devices 2 and a controller (not shown in the figure).
The fixing frame 1 comprises at least two mounting plates 11, and the at least two conveying devices 2 are movably connected with the at least two mounting plates 11 in a one-to-one correspondence mode. Each of the transport devices 2 includes a pair of guide plate members 20 disposed opposite to each other, a supply passage 21 being formed between the pair of guide plate members 20, and the transport devices 2 supply a plurality of reaction containers C through the supply passage 21.
The conveying device 2 may be movably connected to the mounting plate 11 through a moving device, the moving device may include, for example, a guide rail 111 and a slider 112 slidably connected to the guide rail 111, the guide rail 111 is fixedly connected to the mounting plate 11, the conveying device 2 is fixedly connected to the slider 112, and an extending direction of the guide rail 111 is a moving direction of the conveying device 2. The conveying device 2 is movably arranged relative to the mounting plate 11, so that the conveying device 2 is conveniently pulled out of the fixing frame 1 to perform operations such as maintenance, repair and loading of the reaction container C, and then the conveying device 2 is pushed to the fixing frame 1.
In order to increase the stability of the fixing of the conveying devices 2, two displacement devices may be provided in the height direction of each conveying device 2, spaced apart from each other. In order to reduce the weight of the fixing frame 1 and improve the rigidity of the fixing frame 1, the mounting plate 11 may be partially hollowed out, and will not be described in detail. In addition, the number of the conveying devices 2 is at least two, one conveying device 2 is in the current working mode, and the other conveying devices 2 are all standby. The at least two conveying devices 2 are movably connected with the at least two mounting plates 11 in a one-to-one correspondence mode.
The controller is used for monitoring the running state of one conveying device 2 which is currently in the working mode and is supplied to the reaction container C; when the operation state is abnormal, the current transport apparatus 2 is turned off, and another transport apparatus 2 of the at least two transport apparatuses 2 is turned on to continue supplying the reaction containers C. The controller may be provided at any position, for example, fixed to the holder 1, or may be fixed to a position other than the reaction vessel supply device.
When the controller judges that the operation state of one of the conveyor devices 2 currently in the operating mode is abnormal, the current conveyor device 2 may be turned off, and the other conveyor device 2 may be started to continue to supply the reaction containers C. The closed conveying device 2 can be pulled out from the fixing frame 1 for maintenance work such as maintenance and the like, and is pushed into the original position after the maintenance is finished to serve as a standby conveying device 2. The normal work of the other conveying device 2 is not influenced in the whole maintenance process, so that the reaction containers C can be continuously supplied, the time for stopping the machine to process the abnormal problem is reduced, and the working efficiency of the whole machine is improved.
Optionally, the at least two mounting plates 11 of the fixing frame 1 are arranged in parallel, so that the at least two conveying devices 2 are arranged side by side, when the fixing frame is applied to a production line of the sample analysis apparatus, the manipulator can move to the feeding channel 21 of any specified conveying device 2 along the same direction perpendicular to the side by side direction conveniently, and can grab the reaction container C, the movement path of the manipulator is simplified, and the detection efficiency of the sample analysis apparatus is improved.
According to the reaction container supply device provided by the embodiment of the invention, by arranging at least two conveying devices 2 capable of being pushed and pulled, when one conveying device 2 supplies an abnormal reaction container, the conveying device can be replaced by the other conveying device 2, so that the reaction container C can be continuously supplied, the time for stopping to process the abnormal problem is reduced, and the working efficiency of the whole machine is improved. In addition, the reaction container supply device has a compact integral structure, saves space and is favorable for being arranged in the assembly line detection and analysis equipment.
The following describes in detail a specific structure of a reaction vessel supply apparatus according to an embodiment of the present invention with reference to the drawings. For convenience of description, the embodiment of the present invention is described by taking an example in which the reaction vessel supply device includes two transport devices 2.
Referring to fig. 1 and 4 together, the supply path 21 of each of the conveyors 2 has a feed position P1 and a discharge position P2 along its length, and a first sensor 201 is provided on the guide plate member 20 corresponding to the discharge position P2 for sending a first signal to the controller when a reaction vessel C reaches the discharge position P2 and a second signal to the controller when the reaction vessel C is removed.
Optionally, the first sensor 201 is a photosensor. Wherein the first signal indicates that the reaction container C has reached the discharge position P2, and the controller can control the conveying device 2 to suspend conveying the reaction container C, so as to facilitate the removal of the reaction container C by a robot or manually. The second signal indicates that the reaction vessel C at the discharge position P2 is empty, indicating that the reaction vessel C has been removed, at which point the controller may control the transport apparatus 2 to continue transporting the next reaction vessel C.
As an alternative embodiment, the controller is further configured to count the number of times of the first signal sent by the first sensor 201 of the transportation device 2 currently in the operation mode, and determine that the current operation state of the transportation device 2 is abnormal when the number of times of the first signal is equal to the supply threshold of the reaction container C.
The number of times the first sensor 201 sends the first signal is the number of reaction vessels C that have been supplied to the discharge position P2. The supply threshold of the reaction vessels C refers to a threshold of the number of reaction vessels C already supplied in place, which may be, for example, 99.5% of the total number. For example, if the total number of reaction vessels C that can be supplied by the transport apparatus 2 is 1000, the supply threshold is 995. When the number of times of the first signal transmitted by the first sensor 201 is equal to the supply threshold of the reaction container C, it represents that the remaining amount of the reaction container C is insufficient, so that the controller judges that the current operation state of the transport apparatus 2 is abnormal, and needs to switch to another transport apparatus 2, and reload the reaction container C for the transport apparatus 2.
As an optional embodiment, the controller is further configured to determine that the current operation state of the conveying device 2 is abnormal when the first signal or the second signal sent by the first sensor 201 of the conveying device 2 currently in the operating mode is not received within a predetermined time.
The predetermined time is, for example, 1s, and if the controller does not receive the first signal or the second signal within the predetermined time, which indicates that the reaction container C may be jammed due to a failure of the transport apparatus 2, the controller determines that the current operation state of the transport apparatus 2 is abnormal, and needs to switch to another transport apparatus 2, and eliminates the failure problem of the transport apparatus 2.
As described above, when the controller determines that the current operation state of the conveying device 2 is abnormal, the conveying device 2 needs to be pulled out from the fixed frame 1 along the moving device for maintenance, and the conveying device 2 is pushed to the fixed frame 1 after the maintenance is completed. At this time, it is necessary to ensure that the conveying device 2 is pushed to the original position, and safety accidents occurring when the conveying device 2 is started are avoided.
Specifically, the fixing frame 1 further includes a bottom plate 12, the bottom plate 12 is used for supporting at least two conveying devices 2, one end of the bottom plate 12 corresponding to the supply channel 21 is provided with a first magnetic member 121, the guide plate member 20 is provided with a second magnetic member 203 and a second sensor 202, and after the conveying devices 2 move to a predetermined position along the mounting plate 11, the first magnetic member 121 and the second magnetic member 203 are attracted together and trigger the second sensor 202 to send a third signal to the controller.
Alternatively, the first magnetic member 121 is a magnet, the second magnetic member 203 is a metal member having a magnetic attraction property, such as an iron plate, a nickel plate or an iron-nickel alloy plate, and the outer surface is coated with an anticorrosive coating. Alternatively, the second magnetic member 203 may also be an electrolytic lead-containing galvanized sheet, i.e., a galvanized layer is galvanized on the surface of the cold-rolled sheet. Optionally, the second sensor 202 is a micro switch, and the micro switch is a switch triggered by physical machinery, and is not interfered by the property of a triggered object, so that the problem of detection misjudgment caused by a conventional photoelectric sensor can be effectively solved. The second magnetic member 203 and the second sensor 202 are located in the same plane, and when the first magnetic member 121 and the second magnetic member 203 are attracted together, it is indicated that the conveying device 2 moves to a predetermined position along the mounting plate 11, and at this time, the first magnetic member 121 just can touch the second sensor 202, thereby triggering the second sensor 202 to send a third signal to the controller. The third signal indicates that the conveyor 2 has moved to a predetermined position along the mounting plate 11 and can be switched to the operating mode at any time.
In addition, as shown in fig. 3, magnetic beads O are preset in the reaction container C and used for functional modules such as subsequent mixing of the sample with the reaction reagent and detection of the magnetic beads. In order to prevent the first magnetic member 121 from magnetizing the magnetic beads O in the reaction container C and affecting the magnetic bead detection result, the height difference between the first magnetic member 121 and the reaction container C needs to satisfy the predetermined distance. The predetermined distance is related to the magnitude of the magnetic force of the first magnetic member 121, and is determined according to the specific application.
Due to machining errors of the components such as the mounting plate 11 or assembly errors of the components with the guide rail 111 and the slider 112, the conveying devices 2 may be displaced in a direction in which at least two conveying devices 2 are arranged side by side, which may cause abrasion of the conveying devices 2 during operation, which is not favorable for the conveying accuracy of the conveying devices 2 for supplying the reaction containers C.
In order to solve this problem, the bottom plate 12 is further provided with a fixing member 122 at an end corresponding to the supply passage 21, the fixing member 122 is provided with a positioning pin 123, the guide plate member 20 is correspondingly provided with a pin hole 204 engaged with the positioning pin 123, and after the conveying device 2 is moved to a predetermined position along the mounting plate 11, the positioning pin 123 extends into the pin hole 204. Through the cooperation of locating pin 123 and pinhole 204, can fix a position conveyor 2 fast. Meanwhile, the continuous magnetic attraction force generated between the first magnetic piece 121 and the second magnetic piece 203 can ensure that the conveying device 2 does not move in the parallel direction, and the conveying precision of the reaction containers C supplied by the conveying device 2 is further improved.
Referring to fig. 5 to 7, each of the conveying devices 2 includes: support plate 22, turntable 23, conveyor belt 24, and wheel assembly 25.
The support plate 22 is movably connected to the mounting plate 11, and the pair of guide plate members 20 is fixedly connected to the support plate 22. Specifically, the supporting plate 22 is connected to the slider 112 of the aforementioned moving device to realize the movable connection of the supporting plate 22 to the mounting plate 11. The support plate 22 further includes a bent portion 223 parallel to the bottom plate 12, and a pair of guide plate members 20 are provided to the bent portion 223 to form the supply passage 21.
The rotary plate 23 is rotatably connected to the support plate 22, and the rotary plate 23 includes a rotating shaft 231 and a pair of plate bodies 232 coaxially connected to the rotating shaft 231 and spaced apart from each other.
One end of the conveyor belt 24 is wound on the rotating shaft 231 between the pair of disc bodies 232, the conveyor belt 24 is provided with a plurality of reaction containers C arranged in sequence along the length direction thereof, and the reaction containers C are positioned on one side of the conveyor belt 24 departing from the rotating shaft 231.
The rotating wheel assembly 25 is connected to the support plate 22, the rotating wheel assembly 25 is disposed between the rotating disk 23 and the guide plate member 20, and the other end of the conveyor belt 24 is wound around the rotating wheel assembly 25 to guide the reaction containers C on the conveyor belt 24 to the supply path 21.
Further, the wheel assembly 25 includes: a drive motor 251, a drive wheel 252, a first guide wheel 253, and a second guide wheel 254.
The driving motor 251 is electrically connected to the controller and is connected to the support plate 22. The driving wheel 252 is coaxially connected to an output shaft of the driving motor 251, an annular groove 252a is provided in the driving wheel 252, and the other end of the belt 24 is wound around the annular groove 252 a. Specifically, the driving motor 251 and the driving wheel 252 are respectively disposed on two sides of the supporting plate 22 to drive the driving wheel 252 to drive the belt 24 to rotate.
The first guide wheel 253 and the second guide wheel 254 are respectively positioned between the rotating disc 23 and the driving rotating wheel 252 and are in frictional contact with the conveyor belt 24, the first guide wheel 253 is arranged close to the rotating disc 23 and is used for guiding the conveyor belt 24 into the feeding channel 21, and the second guide wheel 254 is positioned on one side of the first guide wheel 253, which is far away from the rotating disc 23, and is positioned above the feeding channel 21 and is used for separating the reaction containers C from the conveyor belt 24.
As shown in fig. 5, the driving wheel 252 is driven by the driving motor 251 to rotate in a counterclockwise direction, the conveyor belt 24 is driven to move in a direction indicated by an arrow in the figure, the conveyor belt 24 wound around the rotating shaft 231 of the rotating disc 23 is wound around the annular groove 252a of the driving wheel 252 under the guidance of the first guide wheel 253 and the second guide wheel 254, and the plurality of reaction containers C disposed on the conveyor belt 24 are conveyed into the feeding passage 21 below the second guide wheel 254.
When the conveyor belt 24 passes through the second guide wheel 254, the reaction container C is separated from the conveyor belt 24 and falls into the supply path 21 below the second guide wheel 254. The separation of the reaction containers C from the conveyor belt 24 is related to the arrangement of the components of the rotating wheel assembly 25 and the structure of the feed path 21.
On the one hand, as shown in fig. 5, a first central connecting line between the central axis of the first guide wheel 253 and the central axis of the second guide wheel 254 is L1, a second central connecting line between the central axis of the second guide wheel 254 and the central axis of the driving pulley 252 is L2, and an included angle θ between the first central connecting line L1 and the second central connecting line L2 is greater than or equal to 90 °.
Since the angle θ between the first center line L1 and the second center line L2 is greater than or equal to 90 °, when the conveyor belt 24 is guided into the feeding path 21 by the first guide wheel 253 and comes into frictional contact with the second guide wheel 254, the reaction container C shown at the rightmost side in FIG. 5 tends to separate from the upwardly moving conveyor belt 24 by its own weight.
On the other hand, as shown in FIGS. 3 and 7, the reaction container C has the ear portions E arranged oppositely, and the ear portions E are connected to the conveyor belt 24. Specifically, the reaction vessel C further includes a vessel body C1, and the ear portions E disposed opposite to each other are connected to the vessel body C1, and the ear portions E are provided with fixing posts C2, and the fixing posts C2 pass through the through holes of the conveyor belt 24, thereby connecting the ear portions E of the reaction vessel C to the conveyor belt 24. The side of each guide plate member 20 facing the supply passage 21 is provided with an inwardly recessed groove 205, and the width dimension d1 between the oppositely disposed ears E is larger than the width dimension d2 of the conveyor belt 24 and smaller than the distance d3 between the pair of grooves 205.
After the conveyor belt 24 is guided into the feeding passage 21, the conveyor belt 24 moves toward the driving wheel 252 under the guiding action of the second guide wheel 254, so as to drive the reaction container C to move upward, the ear portion E of the reaction container C is blocked by the groove 205 provided in the pair of guide plate members 20, the conveyor belt 24 passes through the groove 205 and continues to move upward toward the driving wheel 252, and the reaction container C moves downward under the action of its own gravity, so that the conveyor belt 24 is separated from the reaction container C, and the reaction container C falls into the feeding passage 21.
Referring to fig. 4, 7 to 9, the reaction vessel feeding device further includes a cover assembly 3, the cover assembly 3 includes a cover plate 31 and an extending portion 32, the cover plate 31 covers the feeding channel 21 between the second guide wheel 254 and the discharging position P2, the extending portion 32 is disposed on a side of the cover plate 31 facing the feeding channel 21, and the extending portion 32 is telescopically inserted into the feeding channel 21 under the second guide wheel 254.
As shown in fig. 8 and 9, the lid assembly 3 further includes a toggle member 33 and a hinge 34, and the lid plate 31 is pivotally connected to the guide plate member 20 via the hinge 34 to open or close the supply passage 21. The toggle member 33 is disposed on a side of the cover plate 31 facing away from the supply passage 21 and is connected to the protruding portion 32. One end of the extension part 32 is telescopically inserted between the second guide wheel 254 and the reaction container C in the supply passage 21, and the other end is provided with a cylinder, a spring (not shown) is sleeved outside the cylinder, and the cover plate 31 is correspondingly provided with holes matched with the cylinder and the spring, so that the extension part 32 can telescopically move relative to the cover plate 31. When the toggle member 33 is moved in the arrow direction in fig. 8, the protrusion 32 may be inserted into the supply passage 21 under the second guide wheel 254. When the toggle member 33 is moved in the direction opposite to the arrow direction in fig. 8, the protrusion 32 is withdrawn from the supply passage 21 under the second guide wheel 254, so that the cover plate 31 can be turned over about the hinge 34 to open the supply passage 21.
As shown in fig. 7, magnetic beads O are placed in the reaction container C, and when the conveyor belt 24 is separated from the reaction container C, the opening H of the reaction container C is opened, the reaction container C moves downward and falls into the supply channel 21, and the magnetic beads O tend to escape toward the opening H of the reaction container C due to inertia. By moving the driver 33 to the left, the extension part 32 can be inserted into the supply channel 21 below the second guide wheel 254, and the opening H of the reaction container C separated from the conveyor belt 24 can be covered, thereby preventing the magnetic beads O from escaping from the opening H. In addition, the cover plate 31 covers the supply channel 21 between the second guide wheel 254 and the discharge position P2, so that impurities such as dust can be prevented from falling into the reaction container C, and the cleanliness of subsequent samples and the accuracy of sample analysis results are prevented from being affected.
When the conveyor belt 24 wound around the rotating shaft 231 of the rotating disc 23 is mostly wound around the annular groove 252a of the driving rotating wheel 252 and the conveyor belt 24 is in a tensioned state, the conveyor belt 24 cannot drive the reaction containers C to continue moving toward the feeding channel 21, the controller recognizes that the operation state of the conveying device 2 is abnormal, and controls the driving motor 251 to stop rotating, so that a small amount of reaction containers C fall into the feeding channel 21 and cannot continue moving to the discharging position P2. The conveyor 2 is removed from the fixed frame 1, the toggle member 33 is moved to the right, and then the cover plate 31 is turned over around the pivot of the hinge 34, so that a small number of reaction containers C falling into the feed channel 21 can be manually taken out, and the counting of the reaction containers C arranged on the new conveyor belt 24 is prevented from being affected.
If the counting of the reaction containers C is not required to be considered, the controller does not receive the first signal or the second signal sent by the first sensor 201 of the conveying device 2 currently in the working mode within the preset time to judge the current operating state of the conveying device 2, and a small number of reaction containers C can be manually moved to a proper position, for example, the reaction container C at the forefront of the queue is moved to the discharge position P2, and the rest of the reaction containers C are sequentially arranged, so that the movement of a new conveyor belt 24 is not influenced, and the waste of the reaction containers C is avoided. Then, the cover plate 31 is turned over around the hinge 34 to cover the supply path 21, the toggle member 33 is moved to the left, a new conveyor belt 24 is loaded between the rotary shaft 231 of the rotary table 23 and the rotary wheel assembly 25 again, and the conveyor 2 is moved to the home position of the fixed frame 1 as a spare conveyor.
Referring to fig. 6 again, the supporting plate 22 of the conveying device 2 is provided with a convex pillar 221 and a lock pin 222 rotatably connected with the convex pillar 221 corresponding to the rotating shaft 231 of the turntable 23, the rotating shaft 231 is sleeved on the outer periphery of the convex pillar 221 and pressed on one of the disc bodies 232 through the lock pin 222, and an elastic element 26 is arranged between the other disc body 232 and the supporting plate 22.
Optionally, the elastic member 26 is an O-ring rubber. The force arm for pressing the latch 222 on the tray 232 is short, so that the tray 232 is not easy to be pressed. The elastic part 26 is arranged between the tray body 232 and the support plate 22, so that the friction force generated by extrusion between the tray body 232 and the support plate 22 can be increased, and the purpose of looseness prevention is achieved.
Referring to fig. 10, an embodiment of the present invention further provides a reaction container supply method of the reaction container supply apparatus described above, including:
step S1: acquiring the running state information supplied to the reaction container C by the conveying device 2 in the working mode at present;
step S2: when the running state information is abnormal, sending a stop signal to the current conveying device 2;
step S3: another conveyor 2 of the at least two conveyors 2 is activated to continue feeding the reaction vessels C.
As described above, when the controller determines that the current operation state of the transport apparatus 2 is abnormal, the remaining amount of the reaction container C may be insufficient, or the transport apparatus 2 may be out of order, and it is necessary to pull out the transport apparatus 2 along the moving apparatus from the fixed frame 1 for maintenance, for example, to load the transport apparatus 2 with the reaction container C again, to remove the trouble of the transport apparatus 2, and to push the transport apparatus 2 to the home position of the fixed frame 1 after the maintenance is completed. The maintenance process does not affect the normal work of other conveying devices 2, thereby being capable of continuously supplying the reaction containers C, reducing the time for stopping the machine to process the abnormal problem and improving the work efficiency of the whole machine.
While the invention has been described with reference to a preferred embodiment, various modifications may be made and equivalents may be substituted for elements thereof without departing from the scope of the invention. In particular, the technical features mentioned in the embodiments can be combined in any way as long as there is no structural conflict. It is intended that the invention not be limited to the particular embodiments disclosed, but that the invention will include all embodiments falling within the scope of the appended claims.

Claims (13)

1. A reaction vessel supply apparatus, comprising:
the fixing frame comprises at least two mounting plates;
the conveying devices are movably connected with the mounting plates in a one-to-one correspondence manner; each conveying device comprises a pair of oppositely arranged guide plate pieces, a feeding channel is formed between the pair of guide plate pieces, and the conveying device is used for feeding a plurality of reaction containers through the feeding channel;
the controller is used for monitoring the running state of one conveying device which is currently in the working mode and is supplied to the reaction container; and when the operation state is abnormal, closing the current conveying device, and starting the other conveying device of the at least two conveying devices to continuously supply the reaction containers.
2. The reaction vessel supply apparatus according to claim 1, wherein the supply channel of each of the conveyors has a feed position and a discharge position along its length, and the guide plate member is provided with a first sensor corresponding to the discharge position for sending a first signal to the controller when the reaction vessel reaches the discharge position and a second signal when the reaction vessel is removed.
3. The reaction vessel supply apparatus according to claim 2, wherein the controller is further configured to count the number of times the first signal is sent by the first sensor of the transport apparatus currently in the operation mode, and determine that the current operation state of the transport apparatus is abnormal when the number of times the first signal is equal to the supply threshold value of the reaction vessel.
4. The reaction vessel supplying apparatus according to claim 2, wherein the controller is further configured to determine that the current operating state of the transport apparatus is abnormal when the first signal or the second signal transmitted from the first sensor of the transport apparatus currently in the operating mode is not received within a predetermined time.
5. The reaction vessel supplying device according to claim 1, wherein the fixing frame further comprises a bottom plate, the bottom plate is used for supporting the at least two conveying devices, a first magnetic member is disposed at one end of the bottom plate corresponding to the supplying channel, a second magnetic member and a second sensor are disposed on the guiding plate, and after the conveying devices move to a predetermined position along the mounting plate, the first magnetic member and the second magnetic member are attracted together and trigger the second sensor to send a third signal to the controller.
6. The reaction vessel supply apparatus according to claim 5, wherein a fixing member is further provided at an end of the bottom plate corresponding to the supply passage, the fixing member is provided with a positioning pin, the guide plate member is correspondingly provided with a pin hole for engaging with the positioning pin, and the positioning pin is inserted into the pin hole after the conveying apparatus is moved to the predetermined position along the mounting plate.
7. The reaction vessel supply apparatus according to claim 1, wherein each of the transport apparatuses comprises:
the supporting plate is movably connected with the mounting plate, and the pair of guide plate pieces are fixedly connected with the supporting plate;
the turntable is rotatably connected with the supporting plate and comprises a rotating shaft and a pair of disc bodies which are coaxially connected with the rotating shaft and are arranged at intervals;
one end of the conveying belt is wound on the rotating shaft between the pair of disc bodies, a plurality of reaction containers which are sequentially arranged are arranged on the conveying belt along the length direction of the conveying belt, and the reaction containers are positioned on one side of the conveying belt, which is far away from the rotating shaft;
and the rotating wheel assembly is connected with the supporting plate, is arranged between the rotating disc and the guide plate, and is wound by the other end of the conveying belt to guide the reaction containers on the conveying belt into the supply channel.
8. The reaction vessel feeding device as set forth in claim 7, wherein the rotating wheel assembly includes:
the driving motor is electrically connected with the controller and is connected with the supporting plate;
the driving rotating wheel is coaxially connected with an output shaft of the driving motor, an annular groove is formed in the driving rotating wheel, and the other end of the conveying belt is wound on the annular groove;
first leading wheel and second leading wheel are located respectively the carousel with between the initiative runner, and with conveyer belt frictional contact, first leading wheel is close to the carousel sets up, be used for with the conveyer belt is leading-in supply passage, the second leading wheel is located first leading wheel is kept away from one side of carousel, and is located supply passage's top, be used for with reaction vessel with the conveyer belt separation.
9. The reaction vessel supply apparatus as claimed in claim 8, wherein a first central connecting line between the central axis of the first guide wheel and the central axis of the second guide wheel is L1, a second central connecting line between the central axis of the second guide wheel and the central axis of the driving pulley is L2, and an angle θ between the first central connecting line L1 and the second central connecting line L2 is not less than 90 °.
10. The reaction vessel supply apparatus according to claim 7, wherein said reaction vessels have oppositely disposed ears, and said ears are connected to said conveyor belt, and one side of each of said guide plate members facing said supply passage is provided with an inwardly recessed groove, and a width dimension d1 between said oppositely disposed ears is larger than a width dimension d2 of said conveyor belt and smaller than a distance d3 between said pair of grooves.
11. The reaction vessel feeding device according to claim 8, further comprising a cap assembly including a cap plate covering the feeding passage between the second guide wheel and the discharging position, and an extension portion provided at a side of the cap plate facing the feeding passage and telescopically inserted into the feeding passage under the second guide wheel.
12. The apparatus as claimed in claim 7, wherein the support plate is provided with a boss and a lock pin rotatably connected to the boss corresponding to a rotation shaft of the turntable, the rotation shaft is fitted around an outer circumferential side of the boss and is press-fitted to one of the trays by the lock pin, and an elastic member is provided between the other tray and the support plate.
13. A reaction vessel supply method of the reaction vessel supply apparatus according to any one of claims 1 to 12, comprising:
acquiring running state information supplied to a reaction container by a conveying device in a working mode at present;
when the running state information is abnormal, sending a stop signal to the current conveying device;
activating another of said at least two delivery devices to continue feeding said reaction vessels.
CN202011001581.2A 2020-09-22 2020-09-22 Reactor supply device and reactor supply method Pending CN112129961A (en)

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