CN112120988A - Whitening sunscreen lotion and preparation method thereof - Google Patents
Whitening sunscreen lotion and preparation method thereof Download PDFInfo
- Publication number
- CN112120988A CN112120988A CN202011227142.3A CN202011227142A CN112120988A CN 112120988 A CN112120988 A CN 112120988A CN 202011227142 A CN202011227142 A CN 202011227142A CN 112120988 A CN112120988 A CN 112120988A
- Authority
- CN
- China
- Prior art keywords
- whitening
- sunscreen
- skin
- sun
- added
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000516 sunscreening agent Substances 0.000 title claims abstract description 119
- 230000002087 whitening effect Effects 0.000 title claims abstract description 104
- 230000000475 sunscreen effect Effects 0.000 title claims abstract description 85
- 239000006210 lotion Substances 0.000 title claims abstract description 30
- 238000002360 preparation method Methods 0.000 title abstract description 13
- 239000000839 emulsion Substances 0.000 claims abstract description 43
- 239000003995 emulsifying agent Substances 0.000 claims abstract description 32
- 238000002955 isolation Methods 0.000 claims abstract description 25
- 150000003872 salicylic acid derivatives Chemical class 0.000 claims abstract description 20
- 239000000284 extract Substances 0.000 claims abstract description 18
- 241001165494 Rhodiola Species 0.000 claims abstract description 16
- 229940011403 apple seed extract Drugs 0.000 claims abstract description 16
- 239000003974 emollient agent Substances 0.000 claims abstract description 15
- 239000004615 ingredient Substances 0.000 claims abstract description 12
- 239000003607 modifier Substances 0.000 claims abstract description 12
- 230000014759 maintenance of location Effects 0.000 claims abstract description 4
- 239000004205 dimethyl polysiloxane Substances 0.000 claims description 29
- 235000013870 dimethyl polysiloxane Nutrition 0.000 claims description 29
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims description 29
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 22
- 239000000126 substance Substances 0.000 claims description 21
- 229940008099 dimethicone Drugs 0.000 claims description 16
- -1 polydimethylsiloxane Polymers 0.000 claims description 16
- 230000003020 moisturizing effect Effects 0.000 claims description 15
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 14
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 claims description 14
- 229920006037 cross link polymer Polymers 0.000 claims description 14
- 239000000377 silicon dioxide Substances 0.000 claims description 11
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 claims description 11
- 229920002554 vinyl polymer Polymers 0.000 claims description 11
- YZUUTMGDONTGTN-UHFFFAOYSA-N nonaethylene glycol Chemical compound OCCOCCOCCOCCOCCOCCOCCOCCOCCO YZUUTMGDONTGTN-UHFFFAOYSA-N 0.000 claims description 9
- LCGLNKUTAGEVQW-UHFFFAOYSA-N Dimethyl ether Chemical compound COC LCGLNKUTAGEVQW-UHFFFAOYSA-N 0.000 claims description 8
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 claims description 8
- 229920002385 Sodium hyaluronate Polymers 0.000 claims description 7
- 238000000034 method Methods 0.000 claims description 7
- 229940010747 sodium hyaluronate Drugs 0.000 claims description 7
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims description 7
- 239000004408 titanium dioxide Substances 0.000 claims description 7
- 235000011187 glycerol Nutrition 0.000 claims description 6
- YBGZDTIWKVFICR-JLHYYAGUSA-N Octyl 4-methoxycinnamic acid Chemical compound CCCCC(CC)COC(=O)\C=C\C1=CC=C(OC)C=C1 YBGZDTIWKVFICR-JLHYYAGUSA-N 0.000 claims description 5
- 238000002156 mixing Methods 0.000 claims description 5
- 229960001679 octinoxate Drugs 0.000 claims description 5
- OVYMWJFNQQOJBU-UHFFFAOYSA-N 1-octanoyloxypropan-2-yl octanoate Chemical compound CCCCCCCC(=O)OCC(C)OC(=O)CCCCCCC OVYMWJFNQQOJBU-UHFFFAOYSA-N 0.000 claims description 4
- NFIHXTUNNGIYRF-UHFFFAOYSA-N 2-decanoyloxypropyl decanoate Chemical compound CCCCCCCCCC(=O)OCC(C)OC(=O)CCCCCCCCC NFIHXTUNNGIYRF-UHFFFAOYSA-N 0.000 claims description 4
- JGUMTYWKIBJSTN-UHFFFAOYSA-N 2-ethylhexyl 4-[[4,6-bis[4-(2-ethylhexoxycarbonyl)anilino]-1,3,5-triazin-2-yl]amino]benzoate Chemical compound C1=CC(C(=O)OCC(CC)CCCC)=CC=C1NC1=NC(NC=2C=CC(=CC=2)C(=O)OCC(CC)CCCC)=NC(NC=2C=CC(=CC=2)C(=O)OCC(CC)CCCC)=N1 JGUMTYWKIBJSTN-UHFFFAOYSA-N 0.000 claims description 4
- HIQIXEFWDLTDED-UHFFFAOYSA-N 4-hydroxy-1-piperidin-4-ylpyrrolidin-2-one Chemical compound O=C1CC(O)CN1C1CCNCC1 HIQIXEFWDLTDED-UHFFFAOYSA-N 0.000 claims description 4
- FMRHJJZUHUTGKE-UHFFFAOYSA-N Ethylhexyl salicylate Chemical compound CCCCC(CC)COC(=O)C1=CC=CC=C1O FMRHJJZUHUTGKE-UHFFFAOYSA-N 0.000 claims description 4
- FDATWRLUYRHCJE-UHFFFAOYSA-N diethylamino hydroxybenzoyl hexyl benzoate Chemical compound CCCCCCOC(=O)C1=CC=CC=C1C(=O)C1=CC=C(N(CC)CC)C=C1O FDATWRLUYRHCJE-UHFFFAOYSA-N 0.000 claims description 4
- 229960001630 diethylamino hydroxybenzoyl hexyl benzoate Drugs 0.000 claims description 4
- 229940068171 ethyl hexyl salicylate Drugs 0.000 claims description 4
- 239000011787 zinc oxide Substances 0.000 claims description 4
- LEACJMVNYZDSKR-UHFFFAOYSA-N 2-octyldodecan-1-ol Chemical compound CCCCCCCCCCC(CO)CCCCCCCC LEACJMVNYZDSKR-UHFFFAOYSA-N 0.000 claims description 3
- BTFJIXJJCSYFAL-UHFFFAOYSA-N arachidyl alcohol Natural products CCCCCCCCCCCCCCCCCCCCO BTFJIXJJCSYFAL-UHFFFAOYSA-N 0.000 claims description 3
- FQUNFJULCYSSOP-UHFFFAOYSA-N bisoctrizole Chemical compound N1=C2C=CC=CC2=NN1C1=CC(C(C)(C)CC(C)(C)C)=CC(CC=2C(=C(C=C(C=2)C(C)(C)CC(C)(C)C)N2N=C3C=CC=CC3=N2)O)=C1O FQUNFJULCYSSOP-UHFFFAOYSA-N 0.000 claims description 3
- 229940031569 diisopropyl sebacate Drugs 0.000 claims description 3
- XFKBBSZEQRFVSL-UHFFFAOYSA-N dipropan-2-yl decanedioate Chemical compound CC(C)OC(=O)CCCCCCCCC(=O)OC(C)C XFKBBSZEQRFVSL-UHFFFAOYSA-N 0.000 claims description 3
- 229920003217 poly(methylsilsesquioxane) Polymers 0.000 claims description 3
- 125000003438 dodecyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 claims description 2
- 229940094332 peg-8 dimethicone Drugs 0.000 claims description 2
- YRJKYHIIYRGTCC-UHFFFAOYSA-M potassium;2-hydroxy-4-methoxybenzoate Chemical compound [K+].COC1=CC=C(C([O-])=O)C(O)=C1 YRJKYHIIYRGTCC-UHFFFAOYSA-M 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 27
- 238000012216 screening Methods 0.000 abstract description 24
- 229910000831 Steel Inorganic materials 0.000 abstract description 5
- 239000010959 steel Substances 0.000 abstract description 5
- 206010042496 Sunburn Diseases 0.000 abstract description 4
- 238000013461 design Methods 0.000 abstract description 4
- 239000000463 material Substances 0.000 abstract description 2
- 238000012856 packing Methods 0.000 abstract description 2
- 210000003491 skin Anatomy 0.000 description 70
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 60
- 238000003756 stirring Methods 0.000 description 21
- 239000003921 oil Substances 0.000 description 19
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 16
- 239000000843 powder Substances 0.000 description 12
- 230000037072 sun protection Effects 0.000 description 12
- 239000006071 cream Substances 0.000 description 11
- 238000012360 testing method Methods 0.000 description 11
- 235000019198 oils Nutrition 0.000 description 10
- 244000042430 Rhodiola rosea Species 0.000 description 7
- 235000003713 Rhodiola rosea Nutrition 0.000 description 7
- 239000002537 cosmetic Substances 0.000 description 6
- 238000010438 heat treatment Methods 0.000 description 6
- 238000005282 brightening Methods 0.000 description 5
- 238000004519 manufacturing process Methods 0.000 description 5
- 210000004080 milk Anatomy 0.000 description 5
- 235000013336 milk Nutrition 0.000 description 5
- PLISWQKGWPUZID-UHFFFAOYSA-N 2-hydroxy-4-methoxybenzoic acid;potassium Chemical compound [K].COC1=CC=C(C(O)=O)C(O)=C1 PLISWQKGWPUZID-UHFFFAOYSA-N 0.000 description 4
- 210000004027 cell Anatomy 0.000 description 4
- 238000001816 cooling Methods 0.000 description 4
- 230000006378 damage Effects 0.000 description 4
- 230000019612 pigmentation Effects 0.000 description 4
- 238000005086 pumping Methods 0.000 description 4
- 230000008439 repair process Effects 0.000 description 4
- 239000002904 solvent Substances 0.000 description 4
- 230000002195 synergetic effect Effects 0.000 description 4
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 230000004888 barrier function Effects 0.000 description 3
- 230000000052 comparative effect Effects 0.000 description 3
- 230000007123 defense Effects 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 238000005259 measurement Methods 0.000 description 3
- 239000004005 microsphere Substances 0.000 description 3
- 239000008267 milk Substances 0.000 description 3
- 239000005022 packaging material Substances 0.000 description 3
- 239000002245 particle Substances 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- DOUMFZQKYFQNTF-WUTVXBCWSA-N (R)-rosmarinic acid Chemical compound C([C@H](C(=O)O)OC(=O)\C=C\C=1C=C(O)C(O)=CC=1)C1=CC=C(O)C(O)=C1 DOUMFZQKYFQNTF-WUTVXBCWSA-N 0.000 description 2
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 2
- 102000008186 Collagen Human genes 0.000 description 2
- 108010035532 Collagen Proteins 0.000 description 2
- AFSDNFLWKVMVRB-UHFFFAOYSA-N Ellagic acid Chemical compound OC1=C(O)C(OC2=O)=C3C4=C2C=C(O)C(O)=C4OC(=O)C3=C1 AFSDNFLWKVMVRB-UHFFFAOYSA-N 0.000 description 2
- ATJXMQHAMYVHRX-CPCISQLKSA-N Ellagic acid Natural products OC1=C(O)[C@H]2OC(=O)c3cc(O)c(O)c4OC(=O)C(=C1)[C@H]2c34 ATJXMQHAMYVHRX-CPCISQLKSA-N 0.000 description 2
- 229920002079 Ellagic acid Polymers 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- 102000005348 Neuraminidase Human genes 0.000 description 2
- 108010006232 Neuraminidase Proteins 0.000 description 2
- 208000000453 Skin Neoplasms Diseases 0.000 description 2
- 230000002159 abnormal effect Effects 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 238000009825 accumulation Methods 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 231100000504 carcinogenesis Toxicity 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 229920001436 collagen Polymers 0.000 description 2
- 239000008367 deionised water Substances 0.000 description 2
- 229910021641 deionized water Inorganic materials 0.000 description 2
- 230000008021 deposition Effects 0.000 description 2
- 229960002852 ellagic acid Drugs 0.000 description 2
- 235000004132 ellagic acid Nutrition 0.000 description 2
- 230000001804 emulsifying effect Effects 0.000 description 2
- 210000002615 epidermis Anatomy 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 230000001815 facial effect Effects 0.000 description 2
- 239000004519 grease Substances 0.000 description 2
- 238000000227 grinding Methods 0.000 description 2
- 150000003278 haem Chemical class 0.000 description 2
- 238000009775 high-speed stirring Methods 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- FAARLWTXUUQFSN-UHFFFAOYSA-N methylellagic acid Natural products O1C(=O)C2=CC(O)=C(O)C3=C2C2=C1C(OC)=C(O)C=C2C(=O)O3 FAARLWTXUUQFSN-UHFFFAOYSA-N 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000037311 normal skin Effects 0.000 description 2
- 238000007670 refining Methods 0.000 description 2
- 229940058287 salicylic acid derivative anticestodals Drugs 0.000 description 2
- 239000000523 sample Substances 0.000 description 2
- 229920002545 silicone oil Polymers 0.000 description 2
- 230000009759 skin aging Effects 0.000 description 2
- 201000000849 skin cancer Diseases 0.000 description 2
- 230000005808 skin problem Effects 0.000 description 2
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 description 2
- 210000000434 stratum corneum Anatomy 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- 235000019165 vitamin E Nutrition 0.000 description 2
- 239000011709 vitamin E Substances 0.000 description 2
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 1
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 1
- FJKROLUGYXJWQN-UHFFFAOYSA-M 4-hydroxybenzoate Chemical compound OC1=CC=C(C([O-])=O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-M 0.000 description 1
- 208000002874 Acne Vulgaris Diseases 0.000 description 1
- AFHJQYHRLPMKHU-XXWVOBANSA-N Aloin Natural products O=C1c2c(O)cc(CO)cc2[C@H]([C@H]2[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O2)c2c1c(O)ccc2 AFHJQYHRLPMKHU-XXWVOBANSA-N 0.000 description 1
- 235000009024 Ceanothus sanguineus Nutrition 0.000 description 1
- 235000005979 Citrus limon Nutrition 0.000 description 1
- 244000131522 Citrus pyriformis Species 0.000 description 1
- 241000220284 Crassulaceae Species 0.000 description 1
- JPVYNHNXODAKFH-UHFFFAOYSA-N Cu2+ Chemical compound [Cu+2] JPVYNHNXODAKFH-UHFFFAOYSA-N 0.000 description 1
- 229920000832 Cutin Polymers 0.000 description 1
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 description 1
- 241001523681 Dendrobium Species 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- 229920002307 Dextran Polymers 0.000 description 1
- 206010016322 Feeling abnormal Diseases 0.000 description 1
- 108010022355 Fibroins Proteins 0.000 description 1
- 229920001503 Glucan Polymers 0.000 description 1
- 229920001202 Inulin Polymers 0.000 description 1
- ZSBXGIUJOOQZMP-UHFFFAOYSA-N Isomatrine Natural products C1CCC2CN3C(=O)CCCC3C3C2N1CCC3 ZSBXGIUJOOQZMP-UHFFFAOYSA-N 0.000 description 1
- 240000003553 Leptospermum scoparium Species 0.000 description 1
- 235000015459 Lycium barbarum Nutrition 0.000 description 1
- ZSBXGIUJOOQZMP-JLNYLFASSA-N Matrine Chemical compound C1CC[C@H]2CN3C(=O)CCC[C@@H]3[C@@H]3[C@H]2N1CCC3 ZSBXGIUJOOQZMP-JLNYLFASSA-N 0.000 description 1
- 239000000637 Melanocyte-Stimulating Hormone Substances 0.000 description 1
- 244000131316 Panax pseudoginseng Species 0.000 description 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 241000727169 Prinsepia utilis Species 0.000 description 1
- ZZAFFYPNLYCDEP-HNNXBMFYSA-N Rosmarinsaeure Natural products OC(=O)[C@H](Cc1cccc(O)c1O)OC(=O)C=Cc2ccc(O)c(O)c2 ZZAFFYPNLYCDEP-HNNXBMFYSA-N 0.000 description 1
- ILRCGYURZSFMEG-UHFFFAOYSA-N Salidroside Natural products OC1C(O)C(O)C(CO)OC1OCCC1=CC=C(O)C=C1 ILRCGYURZSFMEG-UHFFFAOYSA-N 0.000 description 1
- 241000320380 Silybum Species 0.000 description 1
- 235000010841 Silybum marianum Nutrition 0.000 description 1
- 244000269722 Thea sinensis Species 0.000 description 1
- 240000007313 Tilia cordata Species 0.000 description 1
- 240000001717 Vaccinium macrocarpon Species 0.000 description 1
- 235000012545 Vaccinium macrocarpon Nutrition 0.000 description 1
- 235000002118 Vaccinium oxycoccus Nutrition 0.000 description 1
- 229930003427 Vitamin E Natural products 0.000 description 1
- RJKYUPXJBBSRML-UHFFFAOYSA-N [4-[(4-amino-3,5-dimethylphenyl)-(2,6-dichlorophenyl)methylidene]-2,6-dimethylcyclohexa-2,5-dien-1-ylidene]azanium;dihydrogen phosphate Chemical compound OP(O)(O)=O.C1=C(C)C(=N)C(C)=CC1=C(C=1C(=CC=CC=1Cl)Cl)C1=CC(C)=C(N)C(C)=C1 RJKYUPXJBBSRML-UHFFFAOYSA-N 0.000 description 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 206010000496 acne Diseases 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- AFHJQYHRLPMKHU-OSYMLPPYSA-N aloin A Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1[C@@H]1C2=CC(CO)=CC(O)=C2C(=O)C2=C(O)C=CC=C21 AFHJQYHRLPMKHU-OSYMLPPYSA-N 0.000 description 1
- SNAAJJQQZSMGQD-UHFFFAOYSA-N aluminum magnesium Chemical compound [Mg].[Al] SNAAJJQQZSMGQD-UHFFFAOYSA-N 0.000 description 1
- 235000001014 amino acid Nutrition 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 210000004381 amniotic fluid Anatomy 0.000 description 1
- 230000003064 anti-oxidating effect Effects 0.000 description 1
- 210000001188 articular cartilage Anatomy 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 230000003750 conditioning effect Effects 0.000 description 1
- 229910001431 copper ion Inorganic materials 0.000 description 1
- 230000006003 cornification Effects 0.000 description 1
- 235000004634 cranberry Nutrition 0.000 description 1
- 210000000695 crystalline len Anatomy 0.000 description 1
- 210000004207 dermis Anatomy 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- PKPOVTYZGGYDIJ-UHFFFAOYSA-N dioctyl carbonate Chemical compound CCCCCCCCOC(=O)OCCCCCCCC PKPOVTYZGGYDIJ-UHFFFAOYSA-N 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 239000002270 dispersing agent Substances 0.000 description 1
- 239000002612 dispersion medium Substances 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 239000012154 double-distilled water Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 1
- 230000002068 genetic effect Effects 0.000 description 1
- 235000008434 ginseng Nutrition 0.000 description 1
- 125000003976 glyceryl group Chemical group [H]C([*])([H])C(O[H])([H])C(O[H])([H])[H] 0.000 description 1
- 229930182470 glycoside Natural products 0.000 description 1
- 150000002338 glycosides Chemical class 0.000 description 1
- 238000009499 grossing Methods 0.000 description 1
- 229920002674 hyaluronan Polymers 0.000 description 1
- 229960003160 hyaluronic acid Drugs 0.000 description 1
- 125000001183 hydrocarbyl group Chemical group 0.000 description 1
- 206010020718 hyperplasia Diseases 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000009776 industrial production Methods 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 229940029339 inulin Drugs 0.000 description 1
- JYJIGFIDKWBXDU-MNNPPOADSA-N inulin Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)OC[C@]1(OC[C@]2(OC[C@]3(OC[C@]4(OC[C@]5(OC[C@]6(OC[C@]7(OC[C@]8(OC[C@]9(OC[C@]%10(OC[C@]%11(OC[C@]%12(OC[C@]%13(OC[C@]%14(OC[C@]%15(OC[C@]%16(OC[C@]%17(OC[C@]%18(OC[C@]%19(OC[C@]%20(OC[C@]%21(OC[C@]%22(OC[C@]%23(OC[C@]%24(OC[C@]%25(OC[C@]%26(OC[C@]%27(OC[C@]%28(OC[C@]%29(OC[C@]%30(OC[C@]%31(OC[C@]%32(OC[C@]%33(OC[C@]%34(OC[C@]%35(OC[C@]%36(O[C@@H]%37[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O%37)O)[C@H]([C@H](O)[C@@H](CO)O%36)O)[C@H]([C@H](O)[C@@H](CO)O%35)O)[C@H]([C@H](O)[C@@H](CO)O%34)O)[C@H]([C@H](O)[C@@H](CO)O%33)O)[C@H]([C@H](O)[C@@H](CO)O%32)O)[C@H]([C@H](O)[C@@H](CO)O%31)O)[C@H]([C@H](O)[C@@H](CO)O%30)O)[C@H]([C@H](O)[C@@H](CO)O%29)O)[C@H]([C@H](O)[C@@H](CO)O%28)O)[C@H]([C@H](O)[C@@H](CO)O%27)O)[C@H]([C@H](O)[C@@H](CO)O%26)O)[C@H]([C@H](O)[C@@H](CO)O%25)O)[C@H]([C@H](O)[C@@H](CO)O%24)O)[C@H]([C@H](O)[C@@H](CO)O%23)O)[C@H]([C@H](O)[C@@H](CO)O%22)O)[C@H]([C@H](O)[C@@H](CO)O%21)O)[C@H]([C@H](O)[C@@H](CO)O%20)O)[C@H]([C@H](O)[C@@H](CO)O%19)O)[C@H]([C@H](O)[C@@H](CO)O%18)O)[C@H]([C@H](O)[C@@H](CO)O%17)O)[C@H]([C@H](O)[C@@H](CO)O%16)O)[C@H]([C@H](O)[C@@H](CO)O%15)O)[C@H]([C@H](O)[C@@H](CO)O%14)O)[C@H]([C@H](O)[C@@H](CO)O%13)O)[C@H]([C@H](O)[C@@H](CO)O%12)O)[C@H]([C@H](O)[C@@H](CO)O%11)O)[C@H]([C@H](O)[C@@H](CO)O%10)O)[C@H]([C@H](O)[C@@H](CO)O9)O)[C@H]([C@H](O)[C@@H](CO)O8)O)[C@H]([C@H](O)[C@@H](CO)O7)O)[C@H]([C@H](O)[C@@H](CO)O6)O)[C@H]([C@H](O)[C@@H](CO)O5)O)[C@H]([C@H](O)[C@@H](CO)O4)O)[C@H]([C@H](O)[C@@H](CO)O3)O)[C@H]([C@H](O)[C@@H](CO)O2)O)[C@@H](O)[C@H](O)[C@@H](CO)O1 JYJIGFIDKWBXDU-MNNPPOADSA-N 0.000 description 1
- AFHJQYHRLPMKHU-UHFFFAOYSA-N isobarbaloin Natural products OC1C(O)C(O)C(CO)OC1C1C2=CC(CO)=CC(O)=C2C(=O)C2=C(O)C=CC=C21 AFHJQYHRLPMKHU-UHFFFAOYSA-N 0.000 description 1
- GOMNOOKGLZYEJT-UHFFFAOYSA-N isoflavone Chemical compound C=1OC2=CC=CC=C2C(=O)C=1C1=CC=CC=C1 GOMNOOKGLZYEJT-UHFFFAOYSA-N 0.000 description 1
- CJWQYWQDLBZGPD-UHFFFAOYSA-N isoflavone Natural products C1=C(OC)C(OC)=CC(OC)=C1C1=COC2=C(C=CC(C)(C)O3)C3=C(OC)C=C2C1=O CJWQYWQDLBZGPD-UHFFFAOYSA-N 0.000 description 1
- 235000008696 isoflavones Nutrition 0.000 description 1
- 230000003780 keratinization Effects 0.000 description 1
- 238000002372 labelling Methods 0.000 description 1
- 229940057995 liquid paraffin Drugs 0.000 description 1
- 229930014456 matrine Natural products 0.000 description 1
- 210000003866 melanoblast Anatomy 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 description 1
- 230000000474 nursing effect Effects 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 229940100460 peg-100 stearate Drugs 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 210000002826 placenta Anatomy 0.000 description 1
- 239000000419 plant extract Substances 0.000 description 1
- 150000008442 polyphenolic compounds Chemical class 0.000 description 1
- 235000013824 polyphenols Nutrition 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 239000008213 purified water Substances 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- DOUMFZQKYFQNTF-MRXNPFEDSA-N rosemarinic acid Natural products C([C@H](C(=O)O)OC(=O)C=CC=1C=C(O)C(O)=CC=1)C1=CC=C(O)C(O)=C1 DOUMFZQKYFQNTF-MRXNPFEDSA-N 0.000 description 1
- TVHVQJFBWRLYOD-UHFFFAOYSA-N rosmarinic acid Natural products OC(=O)C(Cc1ccc(O)c(O)c1)OC(=Cc2ccc(O)c(O)c2)C=O TVHVQJFBWRLYOD-UHFFFAOYSA-N 0.000 description 1
- ILRCGYURZSFMEG-RQICVUQASA-N salidroside Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)OC1OCCC1=CC=C(O)C=C1 ILRCGYURZSFMEG-RQICVUQASA-N 0.000 description 1
- 229940082941 sedum roseum root extract Drugs 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 230000037394 skin elasticity Effects 0.000 description 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 230000003595 spectral effect Effects 0.000 description 1
- 229940032094 squalane Drugs 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 230000001502 supplementing effect Effects 0.000 description 1
- 230000009897 systematic effect Effects 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 230000008719 thickening Effects 0.000 description 1
- 229940042585 tocopherol acetate Drugs 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 230000001052 transient effect Effects 0.000 description 1
- 239000012498 ultrapure water Substances 0.000 description 1
- 238000002211 ultraviolet spectrum Methods 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 235000019155 vitamin A Nutrition 0.000 description 1
- 239000011719 vitamin A Substances 0.000 description 1
- 235000019166 vitamin D Nutrition 0.000 description 1
- 239000011710 vitamin D Substances 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0241—Containing particulates characterized by their shape and/or structure
- A61K8/025—Explicitly spheroidal or spherical shape
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/06—Emulsions
- A61K8/064—Water-in-oil emulsions, e.g. Water-in-silicone emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/27—Zinc; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/29—Titanium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
- A61K8/415—Aminophenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/496—Triazoles or their condensed derivatives, e.g. benzotriazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4966—Triazines or their condensed derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/89—Polysiloxanes
- A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
- A61Q1/02—Preparations containing skin colorants, e.g. pigments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Emergency Medicine (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dispersion Chemistry (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Cosmetics (AREA)
Abstract
The invention provides a whitening sunscreen lotion and a preparation method thereof. The whitening sun-screening isolation emulsion comprises the following components in percentage by total mass: emulsifier: 1.0-4.0%, preferably 1.5-3.0%; and (3) an emollient: 3.0-15.0%, preferably 5.0-13.0%; moisture retention component: 3.0-10.0%, preferably 5.0-8.0%; sunscreen ingredients: 20.0 to 43.0%, preferably 20.0 to 35.0%; skin feel modifier: 2.0-10.0%, preferably 4.0-9.0%; whitening components: 4.0-10.0%, preferably 5.0-8.0%; wherein the whitening component comprises rhodiola root extract, apple seed extract and salicylic acid derivative. The sun-screening emulsion disclosed by the invention has a high sun-screening index, can achieve a daily indoor protection effect and can resist sunburn and suntan of ultraviolet rays under outdoor sunlight irradiation, and meanwhile, the formula is fresh and not greasy through the design of adding steel balls in a packing material.
Description
Technical Field
The invention relates to a whitening sunscreen lotion and a preparation method thereof, belonging to the field of cosmetics.
Background
Whitening products have been a pursued by more women. Modern women are increasingly using make-up products with physical covering that instantly present a fair skin, such as make-up products like liquid foundations, air cushions, loose powder, make-up powder, etc. The product is used for decorating and whitening, and actually treats the symptoms and the root causes, and cannot achieve the long-term effective effect. Whitening needs nursing from inside to outside, and products with whitening effect after long-term use are well popular among female consumers.
In modern cities, sunburn, haze, radiation, color cosmetics and the like have no harm to the skin, and various skin problems such as dull and dull skin, reduced skin elasticity, color spots, wrinkles, acne and the like are caused. The demand of people for protective cosmetics is increased due to the fact that the skin is more and more sensitive due to non-genetic factors, and after skin care lotion, cosmetic water, foundation liquid and sunscreen cream, the sun screen or the sun screen cream becomes one of the cosmetics necessary for modern women.
The existing whitening products solve the whitening problem through one or more different active substances. The sun-screening cream or the sun-screening milk on the market usually aims at preventing sun, separating color makeup and brightening skin color, and part of the sun-screening cream or the sun-screening milk also has certain moisturizing and moistening effects. However, the sun protection index of the existing isolation emulsion is low, and the daily indoor protection effect can only be achieved.
Citation 1 discloses a moisturizing, brightening and whitening make-up cream and a preparation method thereof. The water-moistening, brightening and whitening sun screen comprises the following components in percentage by weight: 2-4% of squalane, 5-7% of vitamin E, 15-19% of vegetable oil, 1-1.5% of sodium carboxymethylcellulose, 4-6% of hyaluronic acid, 1.5-2.5% of rosmarinic acid, 3-5% of tea tree essential oil, 1-2% of titanium dioxide, 1-3% of matrine, 3-5% of barbaloin, 2-5% of silk fibroin and 40-61.5% of deionized water. However, the sun-screening cream has a common sun-screening effect and a common whitening effect, and the sun-screening effect is poor when the sun-screening cream preparation is used outdoors in summer.
Citation 2 discloses a sunscreen concealer, which is prepared from the following raw materials in parts by weight: 0.5-0.7 part of tocopherol acetate, 0.2-0.4 part of p-hydroxybenzoate, 2-3 parts of mesoporous silicon, 20-25 parts of milk thistle, 33-37 parts of dendrobium flowers, 10-13 parts of linden jacquard, 16-20 parts of cranberry, 0.4-0.6 part of polydimethylsiloxane, 1-2 parts of prinsepia utilis royle oil, 40-50 parts of waste hair, 13-15 parts of shell powder, 3-4 parts of glycerol, 1-2 parts of dioctyl carbonate, 1-2 parts of ethylhexyl methoxycinnamate, 0.3-0.5 part of tea polyphenol, 3-4 parts of liquid paraffin, 11-14 parts of freeze-dried white jade blue powder, 3-4 parts of glycerol, 9-13 parts of freeze-dried lemon peel powder, 3-4 parts of colloidal magnesium aluminum silicate, 0.4-0.6 part of PEG100 stearate, 1-2 parts of inulin and 50-60 parts of water. The whitening effect of the makeup base cream is general, and the melanin pigmentation caused by ultraviolet rays cannot be effectively solved. And it also contains various high-cost effective components.
In conclusion, it is a technical problem in the art to research a sunscreen lotion with whitening effect that can solve the facial skin problems such as pigmentation caused by ultraviolet rays, thereby causing color spots and uneven skin color.
Cited documents:
cited document 1: CN 106539715A;
cited document 2: CN 105902464A.
Disclosure of Invention
Problems to be solved by the invention
In view of the technical problems in the prior art, the invention firstly provides a whitening sunscreen lotion which can inhibit the generation of melanin, repair horny cells on the outermost layer of the skin, promote the smooth discharge of the melanin and prevent the excessive deposition of the melanin.
Furthermore, the invention also provides a preparation method of the whitening sunscreen isolation emulsion, which is simple and feasible, has easily controlled reaction conditions and is suitable for mass production.
Means for solving the problems
The invention provides a whitening and sun-screening isolation emulsion, which comprises the following components in percentage by mass:
emulsifier: 1.0-4.0%, preferably 1.5-3.0%;
and (3) an emollient: 3.0-15.0%, preferably 5.0-13.0%;
moisture retention component: 3.0-10.0%, preferably 5.0-8.0%;
sunscreen ingredients: 20.0 to 43.0%, preferably 20.0 to 35.0%;
skin feel modifier: 2.0-10.0%, preferably 4.0-9.0%;
whitening components: 4.0-10.0%, preferably 5.0-8.0%;
wherein the whitening component comprises rhodiola root extract, apple seed extract and salicylic acid derivative.
The whitening and sun-screening isolation emulsion comprises, by mass, 1.5-3.0% of rhodiola root extract, 1.5-4.0% of apple seed extract and 1.0-3.0% of salicylic acid derivative.
The whitening sun-screening isolation emulsion comprises salicylic acid derivatives, wherein the salicylic acid derivatives comprise 4-methoxy potassium salicylate.
The whitening sun-screening barrier emulsion according to the invention, wherein the emulsifier comprises a water-in-oil emulsifier; preferably, the water-in-oil emulsifier comprises PEG-9 dimethiconoethyl dimethicone, lauryl PEG-8 dimethicone, preferably the water-in-oil emulsifier is PEG-9 dimethiconoethyl dimethicone.
The whitening sun-screening isolation emulsion comprises one or more of isopropyl myristate, propylene glycol dicaprylate/dicaprate, diisopropyl sebacate, octyl dodecanol, dimethicone, cyclopentadimethylsiloxane and polydimethylsiloxane.
The whitening sun-screening and isolating emulsion comprises a physical sun-screening agent and a chemical sun-screening agent, wherein the addition amount of the physical sun-screening agent is 8.0-18.0%, and the addition amount of the chemical sun-screening agent is 12.0-25.0%.
The whitening sun-screen barrier emulsion according to the invention, wherein the physical sun-screen agent comprises zinc oxide and/or titanium dioxide; the chemical sunscreen agent comprises one or the combination of more than two of ethylhexyl salicylate, ethylhexyl methoxycinnamate, ethylhexyl triazone, methylene bis-benzotriazolyl tetramethyl butyl phenol and diethyl amino hydroxybenzoyl hexyl benzoate.
The whitening sunscreen isolation emulsion comprises one or more of glycerin, sodium hyaluronate and PEG/PPG-14/7 dimethyl ether.
The whitening sunscreen emulsion comprises silica, one or more of vinyl polydimethylsiloxane/polymethylsiloxane silsesquioxane cross-linked polymer, HDI/trihydroxymethyl hexyl lactone cross-linked polymer and polymethylsilsesquioxane; preferably, the skin feel modifier comprises silica and a vinyl dimethicone/methicone silsesquioxane crosspolymer; more preferably, the silica is added in an amount of 1.0-6.0%, preferably 3.0-6.0%, based on the total mass of the whitening sunscreen lotion; the vinyl polydimethylsiloxane/polymethylsiloxane silsesquioxane crosspolymer is added in an amount of 1.0 to 4.0%, preferably 1.0 to 3.0%.
The invention also provides a preparation method of the whitening sunscreen lotion, which comprises the step of mixing the components of the whitening sunscreen lotion.
ADVANTAGEOUS EFFECTS OF INVENTION
The sun-screening emulsion disclosed by the invention has a high sun-screening index, can achieve a daily indoor protection effect and can resist sunburn and suntan of ultraviolet rays under outdoor sunlight irradiation, and meanwhile, the formula is fresh and not greasy through the design of adding steel balls in a packing material.
Furthermore, the whitening sunscreen isolation emulsion can also provide a concealer function, and achieves the daily makeup bare effect.
Furthermore, the preparation method of the whitening sunscreen emulsion is simple and easy to implement, reaction conditions are easy to control, and the whitening sunscreen emulsion is suitable for mass production.
Detailed Description
Various exemplary embodiments, features and aspects of the invention will be described in detail below. The word "exemplary" is used exclusively herein to mean "serving as an example, embodiment, or illustration. Any embodiment described herein as "exemplary" is not necessarily to be construed as preferred or advantageous over other embodiments.
Furthermore, in the following detailed description, numerous specific details are set forth in order to provide a better understanding of the present invention. It will be understood by those skilled in the art that the present invention may be practiced without some of these specific details. In other instances, methods, means, devices and steps which are well known to those skilled in the art have not been described in detail so as not to obscure the invention.
All units used in the specification are international standard units unless otherwise stated, and numerical values and numerical ranges appearing in the present invention should be understood to include systematic errors inevitable in industrial production.
In the present specification, "%" denotes mass% unless otherwise specified.
In the present specification, the meaning of "may" includes both the meaning of performing a certain process and the meaning of not performing a certain process.
In the present specification, reference to "some particular/preferred embodiments," "other particular/preferred embodiments," "embodiments," and the like, means that a particular element (e.g., feature, structure, property, and/or characteristic) described in connection with the embodiment is included in at least one embodiment described herein, and may or may not be present in other embodiments. In addition, it is to be understood that the described elements may be combined in any suitable manner in the various embodiments.
In the present specification, the numerical range represented by "numerical value a to numerical value B" means a range including the end point numerical value A, B.
In the present specification, the term "water" includes any available water that can be used in the cosmetic field, such as deionized water, distilled water, ion-exchanged water, double distilled water, high purity water, and purified water.
In the present specification, the "room temperature" may be 10 to 40 ℃.
First aspect
The invention provides a whitening sunscreen emulsion, which comprises the following components:
emulsifier: 1.0-4.0%, preferably 1.5-3.0%;
and (3) an emollient: 3.0-15.0%, preferably 5.0-13.0%;
moisture retention component: 3.0-10.0%, preferably 5.0-8.0%;
sunscreen ingredients: 20.0 to 43.0%, preferably 20.0 to 35.0%;
skin feel modifier: 2.0-10.0%, preferably 4.0-9.0%;
whitening components: 4.0-10.0%, preferably 5.0-8.0%;
wherein the whitening component comprises rhodiola root extract, apple seed extract and salicylic acid derivative.
On one hand, the whitening sun-proof isolation emulsion disclosed by the invention is added with rhodiola rosea root extract and apple seed extract as plant whitening components, and the generation of melanin is inhibited through different channels, so that the skin whitening effect is achieved; on the other hand, the salicylic acid derivative is added to further repair the damaged cuticle, promote the peeling of epidermal melanin and achieve the effect of brightening the skin.
< emulsifiers >
In the present invention, the emulsifier used includes a water-in-oil (W/O) emulsifier. Water-in-oil emulsifiers can disperse water in the form of small droplets in an oil, the water phase being the internal or dispersed phase and the oil being the external or dispersion medium. The water-in-oil emulsifier molecule is generally composed of a nonpolar, oleophilic hydrocarbon chain part and a polar, hydrophilic group, and has the dual properties of hydrophilicity and lipophilicity. The invention can greatly reduce the tension of an oil/water interface by adding the emulsifier, and form an interface film by absorbing on the interface, thereby ensuring the stability of the emulsion to a certain extent.
In some specific embodiments, in the present invention, the water-in-oil emulsifier may be a water-in-oil type silicone emulsifier. Specifically, PEG-9 polydimethylsiloxyethyl polydimethylsiloxane may be used as the emulsifier of the present invention. The PEG-9 polydimethylsiloxyethyl polydimethylsiloxane has good compatibility with different grease, and the skin feel is fresh and non-greasy, so that the PEG-9 polydimethylsiloxyethyl polydimethylsiloxane is an ideal water-in-oil emulsifier.
Because the whitening sunscreen isolation emulsion contains the physical sunscreen agent, the powder dispersing agent is required to be added so as to well disperse the powder in the formula. The PEG-9 polydimethylsiloxyethyl polydimethylsiloxane can be used for preparing the water-in-silicone oil isolation emulsion with fresh skin feeling, and a large amount of powder can be dispersed in the silicone oil with low content, so that the oil content required by the dispersed powder can be greatly reduced.
In addition, the packaging design of the whitening sunscreen isolation emulsion is a product which is added with steel balls and is used by shaking, the requirement on the stability of a formula system is low, so that the PEG-9 polydimethylsiloxane ethyl polydimethylsiloxane with low content can disperse a large amount of powder, and can also provide transient stability for the formula system.
In the invention, the addition amount of the emulsifier is 1.0-4.0%, preferably 1.5-3.0% of the total mass of the whitening sunscreen isolation emulsion. When the adding amount of the emulsifier exceeds 4.0%, the skin feeling effect is sticky; when the amount of the emulsifier added is less than 1.0%, the powder is difficult to disperse and the stability does not satisfy the above requirements. Specifically, the emulsifier may be added in an amount of 1.2%, 1.8%, 2.0%, 2.2%, 2.5%, 2.8%, 3.2%, 3.5%, 3.8%, etc.
The whitening sunscreen lotion has fresh skin feeling, the packaging material is added with steel balls, the use method is the design of shaking uniformly before use, the dosage of the emulsifier can be reduced, the greasy feeling of the formula is relieved, and the stimulation effect of the emulsifier on the skin can be reduced.
< emollients >
The specific composition of the emollient is not particularly limited in the present invention, and may be any of those commonly used in the art. Specifically, the emollient may include one or a combination of two or more of isopropyl myristate, propylene glycol dicaprylate/dicaprate, diisopropyl sebacate, octyldodecanol, dimethicone, cyclopentadecyldimethicone, and dimethicone. Preferably, in the present invention, the emollient comprises one or a combination of two or more of propylene glycol dicaprylate/dicaprate, isopropyl myristate, and polydimethylsiloxane.
Further, in the invention, the addition amount of the moisturizing component is 3.0-15.0%, preferably 5.0-13.0% of the total mass of the whitening sunscreen isolation emulsion. Specifically, the amount of the moisturizing component added may be 4.0%, 6.0%, 7.0%, 8.0%, 9.0%, 10.0%, 11.0%, 12.0%, 14.0%, or the like.
< moisture-retaining ingredient >
The specific composition of the moisturizing ingredient in the present invention is not particularly limited, and may be any of those commonly used in the art. Specifically, the moisturizing component can include one or more of sodium hyaluronate, glycerin, propylene glycol, butylene glycol, oat glucan, glyceryl polyether-26, PEG/PPG-14/7 dimethyl ether, and the like. In some specific embodiments, the moisturizing component comprises one or a combination of two or more of sodium hyaluronate, glycerin, and PEG/PPG-14/7 dimethyl ether.
Wherein, sodium hyaluronate is a component inherent in human body, is a dextran aldehyde acid, has no species specificity, is widely present in tissues such as placenta, amniotic fluid, crystalline lens, articular cartilage, skin dermis and the like, and exogenous sodium hyaluronate is used for supplementing endogenous sodium hyaluronate of skin. The relative humidity of the surrounding environment has less effect on its moisturizing properties than other moisturizing ingredients.
Further, in the invention, the addition amount of the moisturizing component is 3.0-10.0%, preferably 5.0-8.0% of the total mass of the whitening sunscreen isolation emulsion. When the addition amount of the moisturizing component is less than 3.0%, the whitening sunscreen isolation emulsion cannot achieve a good moisturizing effect. When the amount of the moisture-retaining component added is more than 10.0%, the skin feels heavy and the use effect is poor. Specifically, the amount of the moisturizing component added may be 4.0%, 4.5%, 6.0%, 7.0%, 7.5%, 9.0%, or the like.
< sunscreen ingredients >
The whitening sunscreen isolation emulsion has a sunscreen effect by adding the sunscreen component. For sunscreen ingredients, physical sunscreens and/or chemical sunscreens may be used in the present invention.
In some specific embodiments, the sunscreen component comprises a physical sunscreen agent and a chemical sunscreen agent, wherein the physical sunscreen agent is added in an amount of 8.0-18.0% and the chemical sunscreen agent is added in an amount of 12.0-25.0% by weight of the total whitening sunscreen lotion. Specifically, the physical sunscreen may be added in an amount of 9.0%, 10.0%, 11.0%, 12.0%, 13.0%, 14.0%, 15.0%, 16.0%, 17.0%, etc.; the chemical sunscreen may be added in amounts of 14.0%, 15.0%, 16.0%, 18.0%, 20.0%, 21.0%, 22.0%, 23.0%, 24.0%, etc.
In particular, the physical sunscreen of the present invention may comprise zinc oxide and/or titanium dioxide. In addition, the average particle size of the physical sunscreen agent of the present invention is preferably 60 to 150 nm. The physical sunscreen agent of the present invention is ultra-fine, such as ultra-fine zinc oxide or titanium dioxide, and is applied to the skin very uniformly, and can reflect and scatter ultraviolet rays, thereby preventing ultraviolet rays from directly contacting the skin. In addition, the physical sunscreen agent does not need to be absorbed by the skin, the burden on the skin is small, the band of the ultraviolet spectrum which can be reflected and scattered is wide, and the sunscreen capability is strong. In addition, the titanium dioxide in the physical sun-screening agent can provide excellent sun-screening performance, and the physical sun-screening agent has good concealing effect, good skin-adhering property and smooth texture. Therefore, the titanium dioxide can provide sun protection and concealer effects, and can play an immediate covering role after being smeared, and has the functions of whitening and homogenizing skin color.
Further, the chemical sunscreen agent of the present invention may include ethylhexyl salicylate, ethylhexyl methoxycinnamate, ethylhexyl triazone, methylene bis-benzotriazolyl tetramethylbutylphenol, diethylamino hydroxybenzoyl hexyl benzoate. Wherein, the ethylhexyl salicylate and the ethylhexyl methoxycinnamate are chemical sunscreen agents with fresh skin feeling. Not only provides the sun protection index of the barrier milk, but also dissolves solid chemical sunscreens such as: ethylhexyl triazone, diethylamino hydroxybenzoyl hexyl benzoate, and the like.
The invention selects the physical sun-screening agent and the chemical sun-screening agent to be matched for use, and can play a role in high sun-screening. Specifically, the whitening sunscreen emulsion has high SPF value and PA value, can effectively prevent the damage of sunlight and other equipment capable of generating ultraviolet light sources to the skin by adding a chemical sunscreen agent and a physical sunscreen agent, and can solve the problem of tanning caused by external environment.
In addition, based on the total mass of the whitening sunscreen lotion, the addition amount of the sunscreen component is 20.0-43.0%, preferably 25.0-35.0%, when the addition amount of the sunscreen agent is less than 20.0%, the sunscreen effect is poor, and when the addition amount of the sunscreen agent is more than 43.0%, the skin feel is sticky. Specifically, the sunscreen agent may be added in an amount of 23.0%, 20.0%, 27.0%, 30.0%, 33.0%, 35.0%, 37.0%, 39.0%, 41.0%, etc.
< whitening ingredients >
The whitening component of the present invention comprises rhodiola root extract, apple seed extract and salicylic acid derivative. According to the invention, the mild rhodiola root extract and the apple seed extract are added, so that the generation of melanin is inhibited from different channels, and the skin whitening effect is achieved mildly; in addition, for the problem of melanin pigmentation caused by skin stratum corneum damage under ultraviolet irradiation, the salicylic acid derivative is added in the skin whitening cream, so that the skin stratum corneum can be repaired, the normal peeling of melanin on the epidermis is promoted, the smooth discharge of the melanin is promoted, the accumulation of the melanin is prevented, and the effects of brightening the skin and whitening the skin are achieved. By using the synergistic effect of the rhodiola root extract, the apple seed extract and the salicylic acid derivative, the excellent whitening effect is further obtained.
Rhodiola rosea is a wild plant of the genus rhodiola of the family Crassulaceae, called 'plateau ginseng', and the rhodiola rosea extract contains rhodiola rosea and rhodiola rosea gylcol, 35 trace elements, 18 amino acids, vitamins A, D, E and other chemical components through chemical analysis, and rhodiola rosea glycoside and rhodiola rosea gylcol in the rhodiola rosea extract have strong antioxidation and can inhibit the damage effect on skin tissues caused by free radicals induced by ultraviolet rays. The salidroside can inhibit melanin a-MSH (a-melanocyte stimulating hormone), block melanin formation, prevent melanin pigmentation, whiten skin, reduce skin inflammation caused by ultraviolet irradiation, and prevent skin redness under sunlight irradiation.
The apple seed extract contains active ingredients such as isoflavone, phytosterol, ellagic acid and the like, wherein the ellagic acid in the apple seeds can inhibit the proliferation of melanoblast cells, complex copper ions in a neuraminidase molecule, inhibit the activity of the neuraminidase, reduce the generation of melanin and achieve the effect of whitening skin. The interaction of the two mild plant extracts can reduce the formation of melanin from different channels and whiten the skin. The skin looks dark due to the excessive presence of melanin, which is increased in the cells in the bottom layer of the epidermal muscle, and normal skin maintains normal skin color by smoothly discharging melanin in a state where the cornification process is good.
As for the salicylic acid derivative, the salicylic acid derivative can coordinate cutin metabolism, correct abnormal hyperplasia of epidermis, promote discharge of melanin, and achieve the purposes of smoothing and whitening skin. In some specific embodiments, the salicylic acid derivative comprises 4-methoxy potassium salicylate. When the skin is irradiated by ultraviolet rays, the horny layer is disordered to generate abnormal keratinization, so that black spots are formed, and the 4-methoxy potassium salicylate can repair the horny cells on the outermost layer of the skin, promote the smooth discharge of melanin, prevent the excessive accumulation of the melanin and brighten the skin.
Based on the total mass of the whitening and sun-screening emulsion, the adding amount of the rhodiola root extract is 1.5-3.0%, the adding amount of the apple seed extract is 1.5-4.0%, and the adding amount of the salicylic acid derivative is 1.0-3.0%; when the added amounts of the rhodiola root extract and apple seed extract and the salicylic acid derivative are within the above ranges, the synergistic effect thereof can be more effectively exerted. Specifically, the addition amount of the rhodiola root extract can be 1.8%, 2.0%, 2.2%, 2.5%, 2.8%, etc.; the addition amount of the apple seed root extract can be 1.8%, 2.0%, 2.2%, 2.5%, 2.8%, 3.0%, 3.2%, 3.5%, 3.8% and the like; the salicylic acid derivative may be added in an amount of 1.2%, 1.5%, 1.8%, 2.0%, 2.2%, 2.5%, 2.8%, etc.
In some specific embodiments, the mass ratio of the rhodiola root extract to the apple seed extract to the salicylic acid derivative is 1: 1-2: 0.5-1.5; when the mass ratio of the rhodiola root extract to the apple seed extract to the 4-methoxy potassium salicylate is 1: 1-2: 0.5-1.5, the whitening effect is optimal under the synergistic effect of the rhodiola root extract and the apple seed extract.
In the invention, the addition amount of the whitening component is 4.0-10.0%, preferably 5.0-8.0% of the total mass of the whitening sunscreen lotion. Specifically, the whitening component may be added in an amount of 4.5%, 4.8%, 5.2%, 5.5%, 5.8%, 6.0%, 6.2%, 6.5%, 6.8%, 7.0%, 7.5%, 7.8%, etc.
< skin feel controlling Agents >
In the invention, the selected skin feel conditioning agents are spherical microspheres, the microspheres provide a roll ball effect, endow the finished product with elegant silk texture, have a certain oil absorption value, can absorb oil of the product, and endow the finished product with smooth texture. Meanwhile, the microsphere powder can absorb grease, has thickening and matte effects and brings soft feeling to skin.
Specifically, in the present invention, the skin feel modifier includes one or a combination of two or more of silica, vinyl polydimethylsiloxane/polymethylsiloxane silsesquioxane crosspolymer, HDI/trimethylolhexyllactone crosspolymer, and polymethylsilsesquioxane.
In some preferred embodiments, the skin feel modifier component of the present invention comprises silica and a vinyl dimethicone/methicone silsesquioxane crosspolymer. Preferably, the adding amount of the silica is 1.0-6.0% of the total mass of the whitening sunscreen lotion; preferably 3.0 to 6.0%, and the vinyl dimethicone/methicone silsesquioxane crosspolymer is added in an amount of 1.0 to 4.0%, preferably 1.0 to 3.0%. When the silica and the vinyl dimethicone/methicone silsesquioxane crosspolymer are added in an amount within the ranges set forth above, the combination absorbs oil and provides a fresh, non-greasy skin feel. Specifically, the silica may be added in an amount of 1.5%, 2.0%, 2.5%, 3.0%, 3.5%, 4.0%, 4.5%, 5.0%, 5.5%, etc.; the vinyl dimethicone/methicone silsesquioxane crosspolymer may be added at 1.2%, 1.5%, 1.8%, 2.0%, 2.2%, 2.5%, 2.8%, 3.2%, 3.5%, etc.
In the invention, the addition amount of the skin feeling modifier is 2.0-10.0%, preferably 4.0-9.0% of the total mass of the whitening sunscreen lotion. If the addition amount of the skin feel regulator is less than 2%, the product is difficult to apply and is greasy; if the amount of the skin-feel modifier added is more than 9%, a phenomenon of rubbing with mud may occur. Specifically, in the present invention, the skin feel modifier may be added in an amount of 2.7%, 3.0%, 3.5%, 4.3%, 5.0%, 5.7%, 6.5%, 7.3%, 8.2%, etc.
< other ingredients >
The whitening sunscreen lotion can also be added with other components which do not influence the functions of the invention. For example: solvents, and the like. The solvent is not particularly limited in the present invention, and may be a solvent commonly used in the art, for example: water, and the like. The amount of the solvent to be added may be adjusted as required.
The whitening sunscreen lotion disclosed by the invention can inhibit the generation of melanin, repair horny cells on the outermost layer of the skin, promote the smooth discharge of the melanin and prevent the excessive deposition of the melanin. The isolation emulsion has a high-efficiency sun protection value, can achieve a daily indoor protection effect and can resist the sunburn and suntan problems of ultraviolet rays under outdoor sunlight irradiation, and meanwhile, the isolation emulsion can be uniformly used by adding steel balls into a packaging material and shaking the packaging material before use, is fresh and cool and is not greasy, otherwise, a large amount of emulsifier is required to be added, and the formula is sticky and greasy. Therefore, after the sunscreen cream is applied, the skin can be prevented from being tanned under the irradiation of ultraviolet rays, so that the effect of whitening the skin is achieved.
Second aspect of the invention
A second aspect of the invention provides a preparation method of the whitening sunscreen lotion according to the first aspect of the invention, which comprises a step of mixing the components of the whitening sunscreen lotion.
Specifically, the method comprises the following steps:
(1) adding phase A (moisture keeping component) into water phase pot, heating to 80-85 deg.C, stirring to dissolve completely, and keeping the temperature for 5-15 min.
(2) Adding the phase C (emulsifier, part of emollient and physical sunscreen agent) into a three-roller machine, grinding, mixing uniformly, and refining without particles for later use; then adding phase B (part of chemical sunscreen agent and the rest of emollient) into oil phase pan, stirring, heating to 80-85 deg.C, keeping the temperature, and stirring for 5-15min to dissolve completely; adding phase C (emulsifier, part of emollient and physical sunscreen agent) into phase B (part of chemical sunscreen agent and the rest of emollient), stirring, heating to 80-85 deg.C, and stirring for 5-15 min.
(3) Pumping the uniformly mixed phase B (part of chemical sunscreen agent and the rest of emollient) and phase C (emulsifier, part of emollient and physical sunscreen agent) into an emulsifying pot, uniformly stirring, slowly pumping the phase A (moisturizing component) under high-speed stirring, keeping the temperature at 80-85 ℃, uniformly stirring at high speed for 5-10min, continuously stirring and cooling, adding the well mixed phase D (rest of chemical sunscreen agent), phase E (skin feel regulator, optionally preservative and optionally essence) and phase F (whitening component) at 45-55 ℃, uniformly stirring, cooling to 30-40 ℃, stopping stirring, and defoaming in vacuum to complete the preparation.
The preparation method is simple and easy to implement, convenient to operate and suitable for mass production.
Examples
Embodiments of the present invention will be described in detail below with reference to examples, but those skilled in the art will appreciate that the following examples are only illustrative of the present invention and should not be construed as limiting the scope of the present invention. The examples, in which specific conditions are not specified, were conducted under conventional conditions or conditions recommended by the manufacturer. The reagents or instruments used are not indicated by the manufacturer, and are all conventional products commercially available.
Examples
The whitening sunscreen isolation emulsion is prepared according to the content (mass percentage) of each component in the formula of the whitening sunscreen isolation emulsion of the examples and the comparative examples in the following tables 1, 3 and 5 according to the following production process steps.
The production process comprises the following steps:
(1) adding the water phase A into a water phase pot, heating to 85 deg.C, stirring to dissolve completely, and maintaining the temperature for 10 min.
(2) Grinding the phase C in a three-roller machine, uniformly mixing, and refining without particles for later use; adding phase B into oil phase pan, stirring, heating to 85 deg.C, stirring for 10min to dissolve completely, adding phase C into phase B, stirring, heating to 85 deg.C, stirring for 10 min.
(3) Pumping the uniformly mixed phase B and phase C into an emulsifying pot, uniformly stirring, slowly pumping the phase A under high-speed stirring, keeping the temperature at 80-85 ℃, uniformly stirring for 10min under stirring, continuously stirring and cooling, adding the well-mixed D, E, F phase at 50 ℃, uniformly stirring, cooling to 35 ℃, stopping stirring, and defoaming in vacuum to finish the preparation.
TABLE 1
Whitening test
1. And (3) testing items: melanin; test objects: for skin use; testing equipment: MPA 9-MexametrMX 18.
2. The working principle of skin melanin and haematochrome is as follows: based on the principle of spectral absorption (RGB), the content of melanin and heme in skin is determined by measuring the reflection of light with specific wavelength on human skin. The test probe of the pigment detector consists of a light source emitter and a light source receiver, and a spring is additionally arranged to keep the pressure on the skin constant during detection. The emitter of the probe emits light with three wavelengths of 568nm, 660nm and 880nm to the skin surface, and the receiver measures the light reflected from the skin. Because the quantity of emitted light is constant, the quantity of light absorbed by skin can be measured, and the contents of melanin and heme in skin can be measured
3. Testing the population: and selecting 28 volunteers for trial, wherein the patients are 25-40 years old, the symptoms are mainly manifested as the phenomenon of uneven and dim complexion of the face, the 28 subjects are randomly divided into 4 groups, and each group respectively uses the whitening sunscreen emulsion of one embodiment or the comparative example.
4. The experimental method comprises the following steps: after cleansing the face every morning and evening, 1g of the whitening sunscreen lotion was applied to the face and the skin melanin in the test area was tested for 1 day and 30 days, respectively, with the results shown in table 2 below.
TABLE 2
As can be seen from table 2, after the whitening sunscreen isolation milks of example 1 and comparative examples 1 to 3 are used, the difference of melanin test in the test area is significant, and the difference of example 1 is larger, which indicates that the whitening sunscreen isolation milks of example 1 have excellent whitening efficacy, and thus the three whitening components of the present application can be obtained to have synergistic effect.
TABLE 3
Test of sun protection value
The principle is as follows: the SPF refers to the sun protection coefficient, is a performance index of the sunscreen cream for preventing from being exposed to the sun and protecting the skin, and shows the sun protection effect; PA is the ability to inhibit skin aging caused by UVA, collagen loss, and skin cancer initiation, more plus signs indicate stronger defense, PA defense is classified into three stages, i.e., PA + + +, PA + for light sun protection, PA + + for moderate sun protection, PA + + + for intense sun protection, and more plus signs indicate stronger UVA protection.
The test method comprises the following steps: the sun protection factor was calculated by the SPF simulator of basf and the SPF and PA values of examples 1-4 were calculated, and the results are shown in table 4. The identification of the protection effect of the long-wave Ultraviolet (UVA) should be based on the actual measurement result of the PFA value, and the UVA protection grade PA is identified on the product label.
When the PFA value is less than 2, the UVA protection effect cannot be identified; when the PFA value is 2-3, marking as PA +; when the PFA value is 4-7, marking as PA + +; when the PFA value is 8-15, marking as PA + + +; when the PFA value is 16 or more, it is marked as PA + + +.
The indication of the Sun Protection Factor (SPF) should be based on the SPF value actually measured for the product. When the actually measured SPF value of the product is less than 2, the sun-screening effect cannot be marked; when the actual measurement SPF value of the product is 2-50 (including 2 and 50, the same below), identifying the actual measurement SPF value; when the measured SPF value of the product is greater than 50, it should be identified as SPF50 +.
TABLE 4
| SPA | PA | Labeling | |
| Example 1 | 50+ | 18.1 | ++++ |
| Example 2 | 47.9 | 15.2 | +++ |
| Example 3 | 45.4 | 18.1 | ++++ |
| Examples4 | 47.6 | 11.2 | +++ |
As can be seen from table 4, the whitening sunscreen lotion of example 1 was identified as SPF50+, PA + + + + +, and the sunscreen effect was most excellent. Therefore, the whitening sunscreen lotion of example 1 can effectively inhibit skin aging caused by UVA, collagen loss, skin cancer initiation ability and defense ability. In addition, the whitening sunscreen lotion of examples 2-4 was superior in sunscreen as compared to the fruit.
TABLE 5
Skin feel experience
And selecting more than 10 qualified volunteers as subjects to participate in the test through volunteer screening. The subjects used the standard facial cleanser to clean the arm areas, 1g of the whitening sunscreen lotion of example 1, example 5 and example 6 was applied to the face after drying, the skin feel was evaluated, the evaluation of the comprehensive score was from low to high of 0 to 10 points, the higher the value, the fresher the skin was, and the results are shown in table 6:
TABLE 6
As can be seen from table 6, the evaluation average of 10 consumers was the highest in example 1, and it was confirmed that the skin feel of example 1 was the cleanest, and the skin feel of examples 5 and 6 was also cleanier.
The above examples of the present invention are merely examples for clearly illustrating the present invention and are not intended to limit the embodiments of the present invention. Other variations and modifications will be apparent to persons skilled in the art in light of the above description. And are neither required nor exhaustive of all embodiments. Any modification, equivalent replacement, and improvement made within the spirit and principle of the present invention should be included in the protection scope of the claims of the present invention.
Claims (10)
1. The whitening sunscreen isolation emulsion is characterized by comprising the following components in percentage by mass:
emulsifier: 1.0-4.0%, preferably 1.5-3.0%;
and (3) an emollient: 3.0-15.0%, preferably 5.0-13.0%;
moisture retention component: 3.0-10.0%, preferably 5.0-8.0%;
sunscreen ingredients: 20.0 to 43.0%, preferably 20.0 to 35.0%;
skin feel modifier: 2.0-10.0%, preferably 4.0-9.0%;
whitening components: 4.0-10.0%, preferably 5.0-8.0%;
wherein the whitening component comprises rhodiola root extract, apple seed extract and salicylic acid derivative.
2. The whitening and sun-blocking lotion according to claim 1, wherein the rhodiola root extract is added in an amount of 1.5-3.0%, the apple seed extract is added in an amount of 1.5-4.0%, and the salicylic acid derivative is added in an amount of 1.0-3.0% based on the total mass of the whitening and sun-blocking lotion.
3. The whitening sunscreen emulsion according to claim 1 or 2, wherein the salicylic acid derivative comprises potassium 4-methoxysalicylate.
4. The whitening sunscreen emulsion according to any of claims 1 to 3, wherein the emulsifier comprises a water-in-oil emulsifier; preferably, the water-in-oil emulsifier comprises PEG-9 dimethiconoethyl dimethicone, lauryl PEG-8 dimethicone, preferably the water-in-oil emulsifier is PEG-9 dimethiconoethyl dimethicone.
5. The whitening sunscreen emulsion according to any of claims 1 to 4, wherein the emollient comprises one or a combination of two or more of isopropyl myristate, propylene glycol dicaprylate/dicaprate, diisopropyl sebacate, octyldodecanol, dimethicone, cyclopentadecyldimethicone, and dimethicone.
6. The whitening sunscreen emulsion according to any of claims 1 to 5, wherein the sunscreen ingredients comprise a physical sunscreen agent and a chemical sunscreen agent, the physical sunscreen agent being added in an amount of 8.0 to 18.0%, and the chemical sunscreen agent being added in an amount of 12.0 to 25.0%.
7. The whitening sunscreen emulsion of claim 6, wherein the physical sunscreen comprises zinc oxide and/or titanium dioxide; the chemical sunscreen agent comprises one or the combination of more than two of ethylhexyl salicylate, ethylhexyl methoxycinnamate, ethylhexyl triazone, methylene bis-benzotriazolyl tetramethyl butyl phenol and diethyl amino hydroxybenzoyl hexyl benzoate.
8. The whitening sunscreen emulsion according to any of claims 1 to 7, wherein the moisturizing component comprises one or a combination of two or more of glycerin, sodium hyaluronate, PEG/PPG-14/7 dimethyl ether.
9. The whitening sunscreen emulsion according to any of claims 1 to 8, wherein the skin feel modifier comprises one or a combination of two or more of silica, vinyl dimethicone/polymethylsiloxane silsesquioxane crosspolymer, HDI/trimethylolhexyllactone crosspolymer, polymethylsilsesquioxane; preferably, the skin feel modifier comprises silica and a vinyl dimethicone/methicone silsesquioxane crosspolymer; more preferably, the silica is added in an amount of 1.0-6.0%, preferably 3.0-6.0%, based on the total mass of the whitening sunscreen lotion; the vinyl polydimethylsiloxane/polymethylsiloxane silsesquioxane crosspolymer is added in an amount of 1.0 to 4.0%, preferably 1.0 to 3.0%.
10. A method of preparing the whitening sunscreen lotion according to any of claims 1 to 9, comprising the step of mixing the components of the whitening sunscreen lotion.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011227142.3A CN112120988A (en) | 2020-11-06 | 2020-11-06 | Whitening sunscreen lotion and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011227142.3A CN112120988A (en) | 2020-11-06 | 2020-11-06 | Whitening sunscreen lotion and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN112120988A true CN112120988A (en) | 2020-12-25 |
Family
ID=73852057
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202011227142.3A Pending CN112120988A (en) | 2020-11-06 | 2020-11-06 | Whitening sunscreen lotion and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN112120988A (en) |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003026532A (en) * | 2001-07-09 | 2003-01-29 | Kose Corp | Skin care preparation |
| CN102657589A (en) * | 2012-05-18 | 2012-09-12 | 通德集团有限公司 | Rhodiola crenulata sun cream |
| CN106176259A (en) * | 2016-08-31 | 2016-12-07 | 天津达仁堂京万红药业有限公司 | A kind of sunscreen cream with dual resisteance and after-sun effect |
| CN109771351A (en) * | 2019-03-28 | 2019-05-21 | 广州睿森生物科技有限公司 | A kind of Whitening, spot composition and its application |
| CN110946771A (en) * | 2019-12-04 | 2020-04-03 | 广州艾蓓生物科技有限公司 | Water-containing oil-controlling loose powder and preparation method thereof |
| CN111184657A (en) * | 2020-02-24 | 2020-05-22 | 广东密尚生物科技有限公司 | Moisturizing isolation emulsion and preparation method thereof |
| CN111450008A (en) * | 2020-04-30 | 2020-07-28 | 广州天玺生物科技有限公司 | Whitening cream and preparation method thereof |
-
2020
- 2020-11-06 CN CN202011227142.3A patent/CN112120988A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003026532A (en) * | 2001-07-09 | 2003-01-29 | Kose Corp | Skin care preparation |
| CN102657589A (en) * | 2012-05-18 | 2012-09-12 | 通德集团有限公司 | Rhodiola crenulata sun cream |
| CN106176259A (en) * | 2016-08-31 | 2016-12-07 | 天津达仁堂京万红药业有限公司 | A kind of sunscreen cream with dual resisteance and after-sun effect |
| CN109771351A (en) * | 2019-03-28 | 2019-05-21 | 广州睿森生物科技有限公司 | A kind of Whitening, spot composition and its application |
| CN110946771A (en) * | 2019-12-04 | 2020-04-03 | 广州艾蓓生物科技有限公司 | Water-containing oil-controlling loose powder and preparation method thereof |
| CN111184657A (en) * | 2020-02-24 | 2020-05-22 | 广东密尚生物科技有限公司 | Moisturizing isolation emulsion and preparation method thereof |
| CN111450008A (en) * | 2020-04-30 | 2020-07-28 | 广州天玺生物科技有限公司 | Whitening cream and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP6474084B2 (en) | Finishing composition comprising silicone fine particles and non-volatile oil | |
| US20200022893A1 (en) | Skincare Formulations and Regimens | |
| WO2010110020A1 (en) | Sunscreen cosmetic | |
| CN109077952B (en) | Blue-light-resistant air cushion CC cream and preparation method thereof | |
| CN103211738A (en) | Beautifying and grooming cream composition containing peony root extractive and pearl powder | |
| CN110897955B (en) | Sunscreen composition and preparation method and application thereof | |
| US9913785B2 (en) | Topical chicory extract skin care composition providing broad spectrum sunscreen | |
| US6673863B2 (en) | Gel composition and methods of use | |
| CN110721120A (en) | Multifunctional skin care cream and preparation method thereof | |
| KR20160094341A (en) | UV block cosmetic composition comprising high inorganic uv absorbers | |
| CN115969749A (en) | Sunscreen composition and preparation method thereof | |
| CN113768853B (en) | Whitening and freckle-removing composition, and preparation method and application thereof | |
| US20220040067A1 (en) | Matt-effect cosmetic composition | |
| CN112120988A (en) | Whitening sunscreen lotion and preparation method thereof | |
| JP2005104894A (en) | Oily cosmetic | |
| CN115024994A (en) | High-safety sunscreen composition and preparation method and application thereof | |
| US20160324762A1 (en) | Dark circle correcting and concealing compositions | |
| CN110496086B (en) | Cool and refreshing sun-proof air cushion containing dendrobium officinale extract and preparation method thereof | |
| JP2004307434A (en) | Water-resistant o/w emulsion composition and water-resistant o/w cosmetic having ultraviolet prevention effect and containing water-resistant o/w emulsion composition therein | |
| CN111467269A (en) | Health product containing Tuber summer fungus extract and its preparation method | |
| CN112791006A (en) | Transparent and refreshing face cream and preparation method thereof | |
| WO2006066741A1 (en) | Cosmetic preparation for extending tanning | |
| CN109350577A (en) | A kind of skin care compositions and its application | |
| CN114146035B (en) | Sun-proof anti-aging face cream and preparation method thereof | |
| JP2004352628A (en) | External preparation for skin |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20201225 |