CN109350577A - A kind of skin care compositions and its application - Google Patents
A kind of skin care compositions and its application Download PDFInfo
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- CN109350577A CN109350577A CN201811529140.2A CN201811529140A CN109350577A CN 109350577 A CN109350577 A CN 109350577A CN 201811529140 A CN201811529140 A CN 201811529140A CN 109350577 A CN109350577 A CN 109350577A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9706—Algae
- A61K8/9717—Rhodophycota or Rhodophyta [red algae], e.g. Porphyra
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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Abstract
The invention discloses a kind of skin care compositions and its application, the skin care compositions comprising following component: emblic berry extract, phllostachys pubescens leaf ext and seaweed extract.The present invention is found through experiments that emblic berry extract, phllostachys pubescens leaf ext and seaweed extract compounding can generate synergistic function at anti-oxidant aspect, the skin care compositions made to have stronger free radical scavenging ability.The skin care compositions can directly remove excessive free radical, can also antioxidant system in reinforcement, inhibit free radical to generate, there is high-efficiency antioxidant effect, anti-aging effects are good, and property is as mild as a dove, and sensitive skin is also suitable.The skin care compositions is added in isolated product by the present invention, and isolation cream is made.Isolation cream not only has preferable isolation, sun-proof result, also has effects that good anti-oxidant, anti-wrinkle and moist, and it is undesirable with the single defect of effect to solve existing isolated product isolation effect.
Description
Technical field
The present invention relates to cosmetic technical field more particularly to a kind of have effects that anti-wrinkle, anti-oxidant and moist skin care
Composition and its application.
Background technique
Isolation is the important protective layer of the injuries such as skin isolation radiation, ultraviolet light and electrical pollution, is the weight for protecting skin
Step is wanted, the makeup of color make-up is also helped, makes dressing more uniform, foundation cream can be prevented to enter skin blocking pore, isolation
Injury of the color make-up to skin.For a long time against computer, if it is calm, thin that skin is easy to chromogenesis without isolation appropriate
Line and early ageing.
Now, on the market isolated product is dazzling, but has the product of preferably isolation sun-proof result few.And
Most of isolated product all only has base isolation effect, cannot without having other skin-care effects such as anti-aging, moisturizing
Meet consumer demand.
Summary of the invention
It is an object of the invention to solve above-mentioned shortcoming and defect existing in the prior art, a kind of skincare composition is provided
Object, which has the multi-efficiencies such as anti-wrinkle, anti-oxidant and moistening skin-care, and is made of plant extracts, naturally, peace
Entirely, when being used in isolated product, it can increase the skin-care effect of isolated product, moreover it is possible to promote the sun-proof result of isolated product.
To realize its purpose, the technical scheme adopted by the invention is as follows:
A kind of skin care compositions comprising following component: emblic berry extract, phllostachys pubescens leaf ext and seaweed extract
Object.
Emblic (Phyllanthus emblica Linn.) is Euphorbiaceae Leafflower xylophyta, fruit fresh food acid
Sweet tea is crisp and micro-puckery, aftertaste are sweet, therefore named emblic also known as pyhllanth usemhlica L., An Luoguo, Niuganguo etc..There are many containing in emblic fruit
Vitamin, microelement, amino acid, organic acid, protein and carbohydrate etc. also contain a large amount of superoxide dismutase (SOD).
SOD is free radical scavenger, can remove free radical O2(ultra-oxygen anion free radical), the SOD in natural extract are easier quilt
Skin absorbs.The emblic berry extract that the present invention uses is purchased from hundred Hao Bo Co., Ltd of Guangzhou, model: EmblicaTM
(130165)。
Moso bamboo (Phyllostachys heterocycla (Carr.) Mitford cv.Pubescens) is that grass family is rigid
Sinobambusa, uniaxial scattered type aiphyllium shape bamboo plant.Moso bamboo is that Chinese cultivated is long, area is most wide, economic value is also most heavy
The bamboo kind wanted, people's food, clothing, housing and transportation, sight, with, decorations various aspects play an important role.It is rich in Moso Bamboo Leaves
Nutrient, such as minerals and amino acid play the role of moist moisturizing to skin.The phllostachys pubescens leaf ext purchase that the present invention uses
From Xi'an Qing Zhi Bioisystech Co., Ltd, article No.: QZ-171047.
Seaweed (Porphyra) is the general designation in marine alternate algae, and predominantly Bangiales section plant laver is lobate
Body, purple or breen.Containing phycobniliprotein and polysaccharide etc. in seaweed extract, there is anti-ultraviolet effect.The present invention
The seaweed extract used is purchased from thousand space Biotechnology Co., Ltd of Guangzhou, model: OB-PL1.
The present invention is found through experiments that emblic berry extract, phllostachys pubescens leaf ext and seaweed extract compound, in anti-wrinkle
Synergistic function can be generated with anti-oxidant aspect, makes the skin care compositions that there is stronger free radical scavenging ability and anti-wrinkle
Effect.The skin care compositions can directly remove excessive free radical, can also antioxidant system in reinforcement, inhibit free radical to produce
It is raw, there is high-efficiency antioxidant effect, anti-aging effects are good, and property is as mild as a dove, and sensitive skin is also suitable.
Preferably, the skin care compositions includes the component of following parts by weight: emblic berry extract 0.01~2 part, mao
0.01~2 part and 0.01~2 part of seaweed extract of bamboo extractive.The present invention is found through experiments that, emblic berry extract, hair
When bamboo extractive and seaweed extract are compounded with said ratio, the synergistic effect of the skin care compositions is more preferable.
It is highly preferred that the skin care compositions includes the component of following parts by weight: 0.5~1.5 part of emblic berry extract,
0.1~1 part and 1~2 part of seaweed extract of phllostachys pubescens leaf ext.
Most preferably, the skin care compositions includes the component of following parts by weight: 1 part of emblic berry extract, Moso Bamboo Leaves
0.5 part and 1.5 parts of seaweed extract of extract.The present invention is found through experiments that, emblic berry extract, phllostachys pubescens leaf ext and
When seaweed extract is compounded with said ratio, the synergistic effect of the skin care compositions is best.
The present invention also provides a kind of cosmetics, contain the skin care compositions.
The present invention also provides a kind of isolation creams, contain the skin care compositions.The skin care compositions can not only make
Isolation cream has the effect of preferable anti-oxidant, anti-wrinkle and moisturizing, moreover it is possible to promote the sun-proof result of isolation cream.
Preferably, weight percentage of the skin care compositions in the isolation cream is 0.1%~5%.The present invention
It being found through experiments that, when dosage of the skin care compositions in isolation cream reaches above-mentioned value, synthesis effect that cream is isolated is preferable,
And cost is relatively low.
Preferably, the isolation cream also contains emulsifier, sun-screening agent, moisturizer, emollient, preservative and thickener.
Preferably, the emulsifier is ring five dimethyl silicone polymer, lauryl PEG-10 tri- (trimethylsiloxy group) silicon
At least one of ethyl polymethyl siloxane, Phosphoric acid monohexadecyl ester potassium, rilanit special.
Preferably, the sun-screening agent is at least one of titanium dioxide, zinc oxide, silica.
Preferably, the moisturizer is at least one of glycerol, butanediol, glycerin polyether -26, ubiquinone.
Preferably, the emollient be Nexbase 2004, dibutyl adipate, Dimethicone Crosspolymer,
At least one of ring five dimethyl silicone polymer.
Preferably, the preservative is at least one of Phenoxyethanol, plant antiseptic agent, Sensiva SC50.
Preferably, the plant antiseptic agent is long and thin hot pepper berry extract, pasque flower extract and palpus extractive of usnea
Composition is purchased from Korean company C&B COSMETIC Co., Ltd., product name EURO-NApre.
Preferably, the thickener is acrylic acid (ester) class, polydimethylsiloxanecopolymer copolymer, the copolymerization of acrylic acid (ester) class
At least one of object sodium.
Preferably, the isolation cream is grouped as by the group of following weight percentage:
A phase: moisturizer 5%~8%, sun-screening agent 2%~4% and emollient 1%~5%；
B phase: moisturizer 4%~6% and emulsifier 2%~4%；
C phase: thickener 2%~5%；
D phase: sun-screening agent 2%~5%；
E phase: the skin care compositions 0.1%~5%；
F phase: preservative 0.01%~1.5%；
Deionized water surplus.
Preferably, the preparation method of the isolation cream, includes the following steps:
(1) with portions of de-ionized water that D phase stock dispersion is uniform, for use；
(2) A phase raw material is added to the container, stirring is warming up to 75~90 DEG C, after mixing, heat preservation for standby use；
(3) B phase raw material is added in vacuum emulsification pot, remaining deionized water is then added, stirring is warming up to 75~90
DEG C, after mixing, heat preservation for standby use；
(4) the A phase raw material of step (2) is pumped into the vacuum emulsification pot equipped with B phase raw material, 3~6min of emulsifying fills
Divide after mixing, continues to keep the temperature 10~15min at 75~90 DEG C, then stirring cooling；
(5) when the material of step (4) is cooled to 40~45 DEG C, C phase raw material is added and the scattered D phase of step (1) is former
Material is uniformly mixed, and E phase raw material is then added, and is uniformly mixed, is eventually adding F phase raw material, is uniformly mixed, and the isolation cream is made.
Preferably, in the preparation method of the isolation cream, the material cooling of step (4) can so be made using at the uniform velocity cooling down
The quality of product is more preferable, more stable.
Compared with prior art, the beneficial effects of the present invention are:
1, the present invention is re-dubbed skin care compositions using emblic berry extract, phllostachys pubescens leaf ext and seaweed extract,
The skin care compositions has effects that high-efficiency antioxidant, and anti-aging effects are good, also has effects that anti-wrinkle and moisturizing, naturally
Safety, it is mildly non-stimulated to skin.
2, the skin care compositions is added in isolated product by the present invention, and isolation cream is made.The isolation cream not only has
Have preferable isolation, sun-proof result, also have effects that anti-oxidant, anti-wrinkle well and moist, solve existing isolated product every
And effect single defect undesirable from effect.
Specific embodiment
To better illustrate the object, technical solutions and advantages of the present invention, the present invention passes through the following example furtherly
It is bright.It should be understood that the embodiment of the present invention is merely to illustrate technical effect of the invention, protection model and is not intended to limit the present invention
It encloses.In embodiment, method therefor is conventional method unless otherwise instructed.
Embodiment 1
The present embodiment 1 provides a kind of skin care compositions, is grouped as by the group of following parts by weight: emblic berry extract 1
Part, 0.5 part of phllostachys pubescens leaf ext and 1.5 parts of seaweed extract.
Embodiment 2
The present embodiment 2 provides a kind of skin care compositions, is grouped as by the group of following parts by weight: emblic berry extract
1.5 parts, 0.5 part of phllostachys pubescens leaf ext and 1 part of seaweed extract.
Embodiment 3
The present embodiment 3 provides a kind of skin care compositions, is grouped as by the group of following parts by weight: emblic berry extract
0.5 part, 0.5 part of phllostachys pubescens leaf ext and 2 parts of seaweed extract.
Embodiment 4
The present embodiment 4 provides a kind of skin care compositions, is grouped as by the group of following parts by weight: emblic berry extract 1
Part, 0.1 part of phllostachys pubescens leaf ext and 1.5 parts of seaweed extract.
Embodiment 5
The present embodiment 5 provides a kind of skin care compositions, is grouped as by the group of following parts by weight: emblic berry extract 1
Part, 1 part of phllostachys pubescens leaf ext and 1.5 parts of seaweed extract.
Embodiment 6
The present embodiment 6 provides a kind of skin care compositions, is grouped as by the group of following parts by weight: emblic berry extract 2
Part, 0.01 part of phllostachys pubescens leaf ext and 2 parts of seaweed extract.
Embodiment 7
The present embodiment 7 provides a kind of skin care compositions, is grouped as by the group of following parts by weight: emblic berry extract
0.01 part, 2 parts of phllostachys pubescens leaf ext and 2 parts of seaweed extract.
Embodiment 8
The present embodiment 8 provides a kind of skin care compositions, is grouped as by the group of following parts by weight: emblic berry extract 2
Part, 2 parts of phllostachys pubescens leaf ext and 0.01 part of seaweed extract.
Embodiment 9
The present embodiment 9 provides a kind of isolation cream, is grouped as by the group of following weight percentage:
A phase: butanediol 6%, titanium dioxide 3% and Nexbase 2004 3%；
B phase: glycerin polyether -26 5% and ring five dimethyl silicone polymer 3%；
C phase: acrylic acid (ester) analog copolymer sodium 3.5%；
D phase: silica 3%；
E phase: the skin care compositions 2% of embodiment 1；
F phase: Phenoxyethanol 0.1% and Sensiva SC50 0.4%；
Deionized water surplus.
The preparation method of the isolation cream, includes the following steps:
(1) with portions of de-ionized water that D phase stock dispersion is uniform, for use；
(2) A phase raw material is added to the container, stirring is warming up to 80 DEG C, after mixing, heat preservation for standby use；
(3) B phase raw material is added in vacuum emulsification pot, remaining deionized water is then added, stirring is warming up to 80 DEG C, mixes
After closing uniformly, heat preservation for standby use；
(4) the A phase raw material of step (2) is pumped into the vacuum emulsification pot equipped with B phase raw material, emulsifying 5min, sufficiently
After mixing, continue to keep the temperature 15min at 80 DEG C, then at the uniform velocity cool down under stiring；
(5) when the material of step (4) is cooled to 40 DEG C, C phase raw material and the scattered D phase raw material of step (1) is added, mixes
It closes uniformly, E phase raw material is then added, be uniformly mixed, be eventually adding F phase raw material, be uniformly mixed, the isolation cream is made.
Embodiment 10
The present embodiment 10 provides a kind of isolation cream, and be only that with the difference of embodiment 9: cream is isolated in the present embodiment 10
In, E phase is the skin care compositions of the embodiment 2 of 2% (weight percentage)；Remaining component and preparation method and 9 phase of embodiment
Together.
Embodiment 11
The present embodiment 11 provides a kind of isolation cream, and be only that with the difference of embodiment 9: cream is isolated in the present embodiment 11
In, E phase is the skin care compositions of the embodiment 3 of 2% (weight percentage)；Remaining component and preparation method and 9 phase of embodiment
Together.
Embodiment 12
The present embodiment 12 provides a kind of isolation cream, and be only that with the difference of embodiment 9: cream is isolated in the present embodiment 12
In, E phase is the skin care compositions of the embodiment 4 of 2% (weight percentage)；Remaining component and preparation method and 9 phase of embodiment
Together.
Embodiment 13
The present embodiment 13 provides a kind of isolation cream, and be only that with the difference of embodiment 9: cream is isolated in the present embodiment 13
In, E phase is the skin care compositions of the embodiment 5 of 2% (weight percentage)；Remaining component and preparation method and 9 phase of embodiment
Together.
Embodiment 14
The present embodiment 14 provides a kind of isolation cream, and be only that with the difference of embodiment 9: cream is isolated in the present embodiment 14
In, E phase is the skin care compositions of the embodiment 6 of 2% (weight percentage)；Remaining component and preparation method and 9 phase of embodiment
Together.
Embodiment 15
The present embodiment 15 provides a kind of isolation cream, and be only that with the difference of embodiment 9: cream is isolated in the present embodiment 15
In, E phase is the skin care compositions of the embodiment 7 of 2% (weight percentage)；Remaining component and preparation method and 9 phase of embodiment
Together.
Embodiment 16
The present embodiment 16 provides a kind of isolation cream, and be only that with the difference of embodiment 9: cream is isolated in the present embodiment 16
In, E phase is the skin care compositions of the embodiment 8 of 2% (weight percentage)；Remaining component and preparation method and 9 phase of embodiment
Together.
Embodiment 17
The present embodiment 17 provides a kind of isolation cream, is grouped as by the group of following weight percentage:
A phase: glycerol 3%, ubiquinone 2%, zinc oxide 2%, dibutyl adipate 0.5% and dimethyl silicone polymer crosslinking are poly-
Close object 0.5%；
B phase: butanediol 4%, glycerin polyether -26 2%, ring five dimethyl silicone polymer 1% and lauryl PEG-10 tri-
(trimethylsiloxy group) silica ethyl polymethyl siloxane 1%；
C phase: polydimethylsiloxanecopolymer copolymer 2% and acrylic acid (ester) analog copolymer sodium 3%；
D phase: titanium dioxide 4% and silica 1%；
E phase: the skin care compositions 0.1% of embodiment 1；
F phase: EURO-NApre plant antiseptic agent 0.01%；
Deionized water surplus.
The preparation method of the isolation cream, includes the following steps:
(1) with portions of de-ionized water that D phase stock dispersion is uniform, for use；
(2) A phase raw material is added to the container, stirring is warming up to 75 DEG C, after mixing, heat preservation for standby use；
(3) B phase raw material is added in vacuum emulsification pot, remaining deionized water is then added, stirring is warming up to 75 DEG C, mixes
After closing uniformly, heat preservation for standby use；
(4) the A phase raw material of step (2) is pumped into the vacuum emulsification pot equipped with B phase raw material, emulsifying 3min, sufficiently
After mixing, continue to keep the temperature 15min at 75 DEG C, then at the uniform velocity cool down under stiring；It can be made by the way of at the uniform velocity cooling down
The quality of product is more preferable, more stable；
(5) when the material of step (4) is cooled to 40 DEG C, C phase raw material and the scattered D phase raw material of step (1) is added, mixes
It closes uniformly, E phase raw material is then added, be uniformly mixed, be eventually adding F phase raw material, be uniformly mixed, the isolation cream is made.
Embodiment 18
The present embodiment 18 provides a kind of isolation cream, is grouped as by the group of following weight percentage:
A phase: butanediol 6%, glycerin polyether -26 2%, silica 1%, titanium dioxide 3% and ring five dimethyl silicone polymer
2% and Nexbase 2004 3%；
B phase: glycerol 4%, Phosphoric acid monohexadecyl ester potassium 2% and rilanit special 2%；
C phase: polydimethylsiloxanecopolymer copolymer 2%；
D phase: titanium dioxide 2%；
E phase: the skin care compositions 5% of embodiment 1；
F phase: EURO-NApre plant antiseptic agent 1.5%；
Deionized water surplus.
The preparation method of the isolation cream, includes the following steps:
(1) with portions of de-ionized water that D phase stock dispersion is uniform, for use；
(2) A phase raw material is added to the container, stirring is warming up to 90 DEG C, after mixing, heat preservation for standby use；
(3) B phase raw material is added in vacuum emulsification pot, remaining deionized water is then added, stirring is warming up to 90 DEG C, mixes
After closing uniformly, heat preservation for standby use；
(4) the A phase raw material of step (2) is pumped into the vacuum emulsification pot equipped with B phase raw material, emulsifying 6min, sufficiently
After mixing, continue to keep the temperature 10min at 90 DEG C, then at the uniform velocity cool down under stiring；It can be made by the way of at the uniform velocity cooling down
The quality of product is more preferable, more stable；
(5) when the material of step (4) is cooled to 45 DEG C, C phase raw material and the scattered D phase raw material of step (1) is added, mixes
It closes uniformly, E phase raw material is then added, be uniformly mixed, be eventually adding F phase raw material, be uniformly mixed, the isolation cream is made.
Comparative example 1
Comparative example 1 provides a kind of isolation cream, and be only that with the difference of embodiment 9: comparative example 1 is isolated in cream, and E phase is
The vitamin E of 2% (weight percentage)；Remaining component and preparation method are same as Example 9.
Comparative example 2
Comparative example 2 provides a kind of isolation cream, and be only that with the difference of embodiment 9: comparative example 2 is isolated in cream, and E phase is
The skin care compositions of 2% (weight percentage), and the skin care compositions is grouped as by the group of following parts by weight: emblic fruit mentions
Take 1 part and 0.5 part of phllostachys pubescens leaf ext of object.Remaining component and preparation method are same as Example 9.
Comparative example 3
Comparative example 3 provides a kind of isolation cream, and be only that with the difference of embodiment 9: comparative example 3 is isolated in cream, and E phase is
The skin care compositions of 2% (weight percentage), and the skin care compositions is grouped as by the group of following parts by weight: emblic fruit mentions
Take 1 part and 1.5 parts of seaweed extract of object.Remaining component and preparation method are same as Example 9.
Comparative example 4
Comparative example 4 provides a kind of isolation cream, and be only that with the difference of embodiment 9: comparative example 4 is isolated in cream, and E phase is
The skin care compositions of 2% (weight percentage), and the skin care compositions is grouped as by the group of following parts by weight: Moso Bamboo Leaves extract
0.5 part and 1.5 parts of seaweed extract of object.Remaining component and preparation method are same as Example 9.
One, safety evaluatio
Human skin pastes patch test: choosing volunteer's conduct without skin allergy history that 100 age brackets are 20~45 years old
Study subject.And subject is randomly divided into 10 groups, every group of 10 people.It is 23~25 DEG C in temperature, humidity is 50%~60%
Under environmental condition, selection subject's inboard arm is tested area, and test point region is 5cm × 5cm, smears embodiment 9 respectively
~18 isolation cream.0.5h, 1h, 2h, 4h, 8h, 12h after smearing, for 24 hours, 48h observe dermoreaction.
It is observed that subject does not occur allergic reaction, illustrate that isolation cream provided by the invention is mildly non-stimulated to skin,
Using safe.
Two, estimation of stability
Estimation of stability is carried out with reference to " GB/T 29665-2013 ".
Heat-resistant stability test: the isolation cream sample of Example 9~18 respectively is placed in 39 DEG C of constant incubator,
It keeps for 24 hours, restoring to room temperature, observes phenomenon.It is observed that it is unchanged to compare appearance before sample and processing, and it is not layered
Phenomenon.
Cold-resistant stability test: the isolation cream sample of Example 9~18 respectively is placed in -8 DEG C of constant incubator,
It keeps for 24 hours, restoring to room temperature, observes phenomenon.It is observed that it is unchanged to compare appearance before sample and processing, and it is not layered
Phenomenon.
Centrifugal test: the isolation cream of Example 9~18 is appropriate respectively, is placed in centrifuge tube, with turning for 2000r/min
Speed is centrifuged 30min, observes phenomenon.It is observed that it is unchanged to compare appearance before sample and processing, and do not occur lamination.
Aforementioned stable test result explanation, isolation cream stability of the invention is good, and each component is uniformly dispersed, and is not susceptible to
Lamination.
Three, anti-wrinkle efficacy assessments
140 25~50 years old volunteers are chosen, are divided into 14 groups at random, every group of 10 people distinguish practical embodiment 9~18
Isolation cream and comparative example 1~4 isolation cream.It is 24~26 DEG C in temperature, the opposite stable environment that humidity is 50%~60%
Under the conditions of tested.Subject smears isolation cream twice in face daily, after using sample, using DermaTOP to tested
Person carries out observation in 8 weeks by a definite date.(VISIOD-3D fast imaging method: skin instant imaging analysis system DermaTOP uses striped
Projection measurement technology is once positioned, the secondary positioning of facial laser, camera intake figure by head and two ear sensors
Picture, three-dimensional cutaneous fast imaging and computer disposal image obtain wrinkle index.) test result is as shown in table 1.
1 anti-wrinkle effect of table
| Group | Wrinkle depth reduced rate (%) |
| Embodiment 9 | 59.6 |
| Embodiment 10 | 57.5 |
| Embodiment 11 | 52.3 |
| Embodiment 12 | 54.1 |
| Embodiment 13 | 55.6 |
| Embodiment 14 | 54.8 |
| Embodiment 15 | 50.7 |
| Embodiment 16 | 52.8 |
| Embodiment 17 | 45.6 |
| Embodiment 18 | 55.3 |
| Comparative example 1 | 10.5 |
| Comparative example 2 | 48.6 |
| Comparative example 3 | 49.2 |
| Comparative example 4 | 22.9 |
It can be seen that from the result of table 1, the isolation cream of the embodiment of the present invention all has preferable anti-wrinkle effect, and effect is obvious
Better than comparative example 1, illustrate that skin care compositions anti-wrinkle effect of the invention is good.
The effect of embodiment 9~16 is analyzed it is found that in the case where same additive amount, with the skin care compositions of embodiment 1
Anti-wrinkle effect it is optimal, illustrate in the skin care compositions, emblic berry extract: phllostachys pubescens leaf ext: seaweed extract=
When 1:0.5:1.5, the anti-wrinkle effect of the skin care compositions is optimal.
The effect of embodiment 9 and comparative example 2~4 is analyzed it is found that emblic berry extract, phllostachys pubescens leaf ext and seaweed mention
When object being taken to be used in compounding, the anti-wrinkle significant effect of the skin care compositions is promoted, and illustrates between three kinds of components there is collaboration to increase
Effect effect.
Again from the result of comparative example 2~4 it is found that the anti-wrinkle effect of comparative example 2 and comparative example 3 is substantially better than comparative example 4, by
This explanation, the main active for playing anti-wrinkle effect is emblic berry extract.
Four, anti-oxidation efficacy is evaluated
Utilize a kind of stable organic free radical 1,1- diphenyl -2- trinitrophenyl-hydrazine (C18H12N5O6, DPPH) and freely
When base scavenger acts on, the characteristic that is become colorless by purple.With DPPH and embodiment and comparative example the effect of cream sample is isolated after,
Quantitative analysis is carried out using spectrophotometry, detects radicals scavenging situation.Specific steps are as follows: successively add in 10mL colorimetric cylinder
Enter 4.0mL DPPH solution and newborn sample is isolated, adds dehydrated alcohol to scale, existed immediately with 1cm cuvette after mixing
Light absorption value (A) is surveyed at 517nm wavelength, light absorption value is denoted as Ai, then surveys light absorption value after 30min is kept in dark place in greenhouse, is denoted as Aj, right
It is the ethanol solution for only adding DPPH according to test, light absorption value is denoted as Ac, and each sample retest 5 times is averaged, as the following formula
It calculates free radical scavenging activity (K):
K (%)=[1- (Ai-Aj)/Ac] × 100%.
Test result is as shown in table 2.
2 anti-oxidation efficacy of table
It can be seen that from the result of table 2, the isolation cream of the embodiment of the present invention has preferable antioxidant effect, and effect is obvious
Better than comparative example 1, say that name skin care compositions of the invention has preferable anti-oxidation efficacy.
The effect of embodiment 9~16 is analyzed it is found that in the case where same additive amount, with the skin care compositions of embodiment 1
Antioxidant effect it is optimal, illustrate in the skin care compositions, emblic berry extract: phllostachys pubescens leaf ext: seaweed extract
When=1:0.5:1.5, the antioxidant effect of the skin care compositions is optimal.
The effect of embodiment 9 and comparative example 2~4 is analyzed it is found that emblic berry extract, phllostachys pubescens leaf ext and seaweed mention
When object being taken to be used in compounding, the antioxidant effect of the skin care compositions is obviously improved, and illustrates there is collaboration between three kinds of components
Synergistic effect.
Again from the result of comparative example 2~4 it is found that the antioxidant effect of comparative example 2 and comparative example 3 is substantially better than comparative example 4,
Thus illustrate, the main active for playing anti-oxidation efficacy is emblic berry extract.
Five, UV protection evaluation
The subject for randomly selecting 140 unglazed allergies is divided into 14 groups.It first measures every subject and isolation is not used
The value of the ultraviolet energy (MED, Minimal Erythema Dose) for causing skin minimum erythema of newborn sample, subject exist
Under opposite stable environment, isolation cream is smeared in the region the 5cm × 5cm quantification of inboard arm, then simulate daylight, foundation with xenon lamp
The MED of subject and the sun protection factor (SPF, Sun Protection Factor) that newborn sample estimation is isolated, carry out from low to high
The MED for applying sunscreen cosmetic is measured in irradiation.The MED/ that then individual SPFi=applies the newborn sample of isolation does not apply the MED that newborn sample is isolated；
Newborn sample SPF=SPFi/50 is isolated.
Test result is as shown in table 3.
3 sun-proof function of table
| Group | Sun protection factor (SPF) |
| Embodiment 9 | 18±2 |
| Embodiment 10 | 15±3 |
| Embodiment 11 | 19±3 |
| Embodiment 12 | 14±2 |
| Embodiment 13 | 18±2 |
| Embodiment 14 | 16±1 |
| Embodiment 15 | 17±2 |
| Embodiment 16 | 13±2 |
| Embodiment 17 | 11±3 |
| Embodiment 18 | 15±1 |
| Comparative example 1 | 6±1 |
| Comparative example 2 | 7±2 |
| Comparative example 3 | 12±3 |
| Comparative example 4 | 11±3 |
It can be seen that from the result of table 3, the isolation cream of the embodiment of the present invention all has preferable sun-proof result, and effect is obvious
Better than comparative example 1, illustrate that skin care compositions of the invention can effectively promote the sun-proof function of isolation cream of inventive formulation.
In conjunction with the embodiments with the result of comparative example 2~4 it is found that in the case where same additive amount, the isolation cream of embodiment
Sun-proof result be better than the sun-proof result of comparative example, illustrate, emblic berry extract, phllostachys pubescens leaf ext and seaweed extract
When being used in compounding, effect of the skin care compositions on the newborn sun-proof function of promotion isolation is more preferable.
Again from the result of comparative example 2~4 it is found that the sun-proof result of comparative example 3 and comparative example 4 is better than comparative example 2, this is
Because containing seaweed extract in comparative example 3 and comparative example 4, illustrate that the addition of seaweed extract helps to promote the anti-of isolation cream
Shine effect.
Finally, it should be noted that the above embodiments are merely illustrative of the technical solutions of the present invention rather than protects to the present invention
The limitation of range is protected, although the invention is described in detail with reference to the preferred embodiments, those skilled in the art should
Understand, it can be with modification or equivalent replacement of the technical solution of the present invention are made, without departing from the essence of technical solution of the present invention
And range.
Claims (9)
1. a kind of skin care compositions, which is characterized in that including following component: emblic berry extract, phllostachys pubescens leaf ext and purple
Dish extract.
2. skin care compositions as described in claim 1, which is characterized in that the component including following parts by weight: emblic fruit mentions
Take 0.01~2 part of object, 0.01~2 part of phllostachys pubescens leaf ext and 0.01~2 part of seaweed extract.
3. skin care compositions as claimed in claim 2, which is characterized in that the component including following parts by weight: emblic fruit mentions
Take 0.5~1.5 part of object, 0.1~1 part of phllostachys pubescens leaf ext and 1~2 part of seaweed extract.
4. skin care compositions as claimed in claim 3, which is characterized in that the component including following parts by weight: emblic fruit mentions
Take 1 part of object, 0.5 part of phllostachys pubescens leaf ext and 1.5 parts of seaweed extract.
5. a kind of cosmetics, which is characterized in that containing such as the described in any item skin care compositions of Claims 1 to 4.
6. a kind of isolation cream, which is characterized in that weight percentage, containing such as the described in any item shields of Claims 1 to 4
Skin composition 0.1%~5%.
7. isolation cream as claimed in claim 6, which is characterized in that also contain emulsifier, sun-screening agent, moisturizer, emollient, prevent
Rotten agent and thickener；
Preferably, the emulsifier is ring five dimethyl silicone polymer, lauryl PEG-10 tri- (trimethylsiloxy group) silica ethyl
At least one of polymethyl siloxane, Phosphoric acid monohexadecyl ester potassium, rilanit special；
Preferably, the sun-screening agent is at least one of titanium dioxide, zinc oxide, silica；
Preferably, the moisturizer is at least one of glycerol, butanediol, glycerin polyether -26, ubiquinone；
Preferably, the emollient is Nexbase 2004, dibutyl adipate, Dimethicone Crosspolymer, ring five
At least one of dimethyl silicone polymer；
Preferably, the preservative is at least one of Phenoxyethanol, plant antiseptic agent, Sensiva SC50；
Preferably, the plant antiseptic agent is the combination of long and thin hot pepper berry extract, pasque flower extract and palpus extractive of usnea
Object；
Preferably, the thickener is acrylic acid (ester) class, polydimethylsiloxanecopolymer copolymer, acrylic acid (ester) analog copolymer sodium
At least one of.
8. isolation cream as claimed in claim 7, which is characterized in that be grouped as by the group of following weight percentage:
A phase: moisturizer 5%~8%, sun-screening agent 2%~4% and emollient 1%~5%；
B phase: moisturizer 4%~6% and emulsifier 2%~4%；
C phase: thickener 2%~5%；
D phase: sun-screening agent 2%~5%；
E phase: the skin care compositions 0.1%~5%；
F phase: preservative 0.01%~1.5%；
Deionized water surplus.
9. the preparation method of isolation cream as claimed in claim 8, which comprises the steps of:
(1) with portions of de-ionized water that D phase stock dispersion is uniform, for use；
(2) A phase raw material is added to the container, stirring is warming up to 75~90 DEG C, after mixing, heat preservation for standby use；
(3) B phase raw material is added in vacuum emulsification pot, remaining deionized water is then added, stirring is warming up to 75~90 DEG C, mixes
After closing uniformly, heat preservation for standby use；
(4) the A phase raw material of step (2) is pumped into the vacuum emulsification pot equipped with B phase raw material, 3~6min of emulsifying, it is sufficiently mixed
After closing uniformly, continue to keep the temperature 10~15min at 75~90 DEG C, then stirring cooling；
(5) when the material of step (4) is cooled to 40~45 DEG C, C phase raw material and the scattered D phase raw material of step (1) is added, mixes
It closes uniformly, E phase raw material is then added, be uniformly mixed, be eventually adding F phase raw material, be uniformly mixed, the isolation cream is made.
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| CN116919867A (en) * | 2023-07-20 | 2023-10-24 | 广州市精锐生物研究有限公司 | Whitening concealer uvioresistant composition and preparation method and application thereof |
| CN116919867B (en) * | 2023-07-20 | 2024-05-14 | 广州市精锐生物研究有限公司 | Whitening concealer uvioresistant composition and preparation method and application thereof |
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