KR101590803B1 - Cosmetic composition for quick whitening or improving skin tone comprising calamine - Google Patents

Abstract

The present invention relates to a cosmetic composition for quick whitening or skin tone improving, comprising calamine and, more specifically, to a cosmetic composition having an excellent quick whitening effect and skin tone improving effect, and having an excellent moisturizing function, comprising calamine.

Description

[0001] The present invention relates to a cosmetic composition for quick whitening or improving skin tone comprising calamine,

The present invention relates to a cosmetic composition having an immediate whitening effect or a complexion-improving effect, including calamine, and having excellent moisturizing power.

In general, human epidermis is divided into stratum corneum, granular layer, superficial layer, and basal layer in order from the surface. Melanin-forming cells, which are melanin-producing cells, are located in the basal layer at the bottom. In the basal layer, melanin is produced by tyrosinase, which is a melanin producing enzyme, and cells having this melanin are brought up to the stratum corneum. The time required for melanin to reach the stratum corneum is about 25 to 30 days.

In general, people instinctively pursue beauty. One of the many ways to pursue beauty is whitening, which means whitening is beautiful and whitening. The whitening effect in such a skin becomes possible by inhibiting the production of melanin or inhibiting the movement of melanosome. As a result of this mechanism, substances registered as a whitening ingredient by the pharmaceutical company are mulberry extract, arbutin, ethyl ascorbyl ether, useful licorice extract, ascorbyl glucoside, niacinamide, alpha-bisabolol and ascorbyl tetraisopalmitate .

However, as mentioned earlier, this general whitening action inhibits the production of melanin, and it requires about 30 days because the cells in the basal layer without melanin must rise to the stratum corneum. Therefore, it takes a long time for the user of the whitening product to realize the effect, so that the user feels that the whitening is not practically quickly. As a result, on the market, there is a continuous release of whitening or facial color improvement products that instantly brighten the face when the product is applied.

The effect of this immediate whitening or anti-color improvement product is mostly the effect caused by the pigment such as titanium dioxide or titanium dioxide. These pigments have a high refractive index and thus appear to have a bright skin tone, but recently it has been found that titanium dioxide nanoparticles have safety problems such as carcinogenicity, genotoxicity and oxidative DNA damage (Benedicte Trouiller, et al. Titanium Dioxide Nanoparticles Induce DNA Damage and Genetic Instability In vivo in Mice, Cancer Res 2009; 69 (22): 8784-9). Therefore, some consumers are concerned about skin hazards caused by these pigment residues.

Calamine (Calamine) is a raw material used for quasi-drugs, and is effective for inflammation, itching, eczema and so on and is generally applied to lotion-type quasi-drugs. These calamins were classified as medicines before the revision of Notification No. 2007-48 of the Ministry of Health and Welfare, but their efficacy and safety were proved, and the lotion containing calamine was classified as quasi-drugs according to the quasi-drug specification rule. Calamine lotions, which are generally marketed as quasi-commercially, are used to relieve the symptoms of sunburn, eczema, rashes, urticaria, poisoning by plants, chickenpox and insect bites.

Kalamin can be used in cosmetics according to the provisions of the Food and Drug Administration Notification No. 2010-99 on Cosmetic Ingredients Designation, but the coloramine-containing cosmetics sold on the market are used only in the conceptual category of acne products, but they are not widely used I can not.

Accordingly, the inventors of the present invention have confirmed that a cosmetic composition having an excellent moisturizing power can be prepared while improving the complexion by imparting a whitening effect immediately by containing calamine, thereby completing the present invention.

Accordingly, a problem to be solved by the present invention is to provide a cosmetic composition for immediate whitening or complexion improvement containing calamine.

Another object of the present invention is to provide an immediate whitening or facial color improvement method comprising the step of applying the cosmetic composition to the skin.

In order to solve the above problems, the present invention provides a cosmetic composition for immediate whitening or complexion improvement comprising calamine.

The present invention also provides an immediate whitening or facial improvement method comprising applying the cosmetic composition to the skin.

Hereinafter, the present invention will be described more specifically.

As used herein, the term " immediate whitening " means an immediate improvement in lightness, i.e. an increase in the value. The CIE L * a * b * color space is a color space created by nonlinear transformation of the CIE XYZ color space based on the human vision theory. The value representing the brightness in this color space is the L * value. When L * value is 0, it indicates black, and when L * value is 100, it indicates white. That is, as soon as the cosmetic is applied, the L * value indicating the objective brightness is immediately increased, and the brightness of the skin is immediately brightened.

The term " improvement of complexion " as used in the present invention means a sensual concept involving subjective judgment that the complexion improves satisfactorily. That is, in general, an increase in the brightness value has an effect of improving the complexion, but the increase in the unconditional brightness value does not mean that the complexion improves. If the brightness value is increased too much, the satisfaction of make-up may be lowered and the effect of improving the complexion may be lowered.

The present invention provides a cosmetic composition for immediate skin whitening or complexion improvement comprising calamine.

In the present invention, the calamine preferably comprises 10 to 25% by weight, more preferably 15 to 20% by weight based on the total weight of the composition. When the amount of the coloramine is more than 25% by weight based on the total weight of the composition, whitening occurs and the satisfaction of the improvement of the complexion is low. When the amount of the above-mentioned calmimin is less than 10% by weight based on the total weight of the composition, the whitening effect is insignificant immediately.

The above-mentioned calamine is a raw material in the form of a pink powder having the effects of inflammation, itching, eczema and the like, which can be easily obtained commercially, and a person skilled in the art can easily produce a modified May be included in the calamine of the present invention.

In the present invention, the composition may be any one selected from the group consisting of an aqueous dispersion type, an aqueous type, a water-in-oil type, and an oil dispersion type, but is not limited thereto.

In the formulations, the aqueous dispersions are meant to be dispersible in the aqueous component, that is, dispersed in the aqueous component.

In the formulation, the underwater type is an oil-in-water (o / w) emulsified form, and the external phase (continuous phase) is water phase and the internal phase (non-continuous phase) is oil phase.

In one embodiment of the present invention, a water-in-oil type cosmetic composition containing a calamine is prepared by mixing and dispersing a calamine in an aqueous phase component and then adding an oil-based component mixed solution.

In the formulation, the water-in-oil type is a water-in-oil (w / o) emulsion type in which the external phase (continuous phase) is an oil phase and the internal phase (non-continuous phase) is water phase. .

In one embodiment of the present invention, a water-in-oil type cosmetic composition containing a calamine is prepared by mixing and dispersing a calamine in an oil-based component, It was confirmed that not only whitening or complexion improvement, but also moisture retention and skin irritation were not observed. Accordingly, the water-in-oil type cosmetic composition containing the above-mentioned calamine can be used as a cosmetic composition for moisturizing as well as improving skin whiteness and complexion immediately.

In the formulation, the oil dispersion type refers to a dispersion capable of dispersing in an oil phase component, that is, a dispersion of a calamine in an oil phase component.

In the formulation, the water-based component may contain water as a solvent, propanediol as a moisturizing agent, glycerin, butylene glycol, propylene glycol, dipropylene glycol ) May contain at least one polyol selected from the group consisting of pentylene glycol, hexylene glycols, polyethylene glycols and sorbitol, But is not limited to.

The oily component may contain, as an oil component, a cyclic silicone oil such as cyclopentasiloxane, cyclohexasiloxane, decamethyl cyclopentasiloxane, octamethyl cyclopentasiloxane, and the like, -20 volatile oils of the hydrocarbon and vegetable oils such as Phytosqualane, Ethylhexyl Palmitate, Butylene Glycol Dicaprylate / Dicaprate, Caprylic / Capric Triglyceride Caprylic / Capric Triglyceride, Triethylhexanoin, Diisostearyl Malate, Polyglyceryl-2 Triisostearate, Dicaprylyl Carbonate, , Ester type oils such as isononyl isononanoate and the like, A silicone oil such as Phenyl Trimethicone, Methyl Trimethicone, Dimethicone, Caprylyl Methicone, Dipheynylsiloxy Phenyl Trimethicone and the like, (Ozokerite), Ceresin, Carnauba Wax, Candelilla Wax, Paraffin Wax, Behenyl Alcohol, Lecithin, Polyhydroxy But are not limited to, polyhydroxystearic acid, isopropyl myristate, isostearic acid, stearoyl inulin, dextrin palmitate, glyceryl behenate / It is also known that it can be used in combination with other materials such as Glyceryl Behenate / Eicosadioate, Disteardimonium Hectorite, Stearalkonium Hectorite, Bentonite, Silica Dimethylsilylate (S ilica Dimethyl Silylate), acrylate / ethylhexyl acrylate / dimethicone methacrylate copolymer, Fatty Alcohol, Fatty Acid, and higher alcohols (Higher Alcohol) may be used, but the present invention is not limited thereto.

In addition to the above components, at least one selected from emulsifiers, polysaccharide moisturizers, emulsion stabilizers, pigments, fragrances, preservatives, thickeners, and other additives commonly used in the production of cosmetics may be further mixed into the cosmetic composition.

As the emulsifier, Cetyl PEG / PPG-10/1 Dimethicone, Lauryl PEG-8 Dimethicone, Cetearyl Alcohol Lauryl PEG-10 Tris (Trimethylsiloxy) silylethyl Dimethicone), Sorbitan Olivate), Cetearyl Glucoside, Lauryl Phosphate-10 Tris (trimethylsiloxy) , Lauryl dimethicone / polyglycerin-3 crosspolymer, PEG-10 dimethicone, phage-9 polydimethylsiloxy ethyl cholate (PEG-10 dimethicone) -9 Polydimethylsiloxyethyl Dimethicone, Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone, Sorbitan Sesquioleate, Glyceryl Stearate, PEG-100 stearate (PEG-100 Stearate), sorbitan stearate (PEG / PPG-19/19 Dimethicone), PEG-30 Dipolyhydroxystearate, PEGi / PPG-19/19 Dimethicone, PEG-30 Dipolyhydroxystearate, Sorbitan Stearate, 20/20 Dimethicone (PEG / PPG-20/20 Dimethicone), Sorbitan Isostearate, Lauryl PEG / PPG-18/18 Methicone Ceteareth-12, PEG-60 Glyceryl Isostearate, Polysorbate 20, Polysorbate 60, Polysorbate 80, Polysorbate 80, Behenyl Alcohol, Potassium Cetyl Phophate, Cetearyl Olivate, PEG-60 Hydrogenated Castor Oil, Hydrogenase, Hydrogenated Lecithin, Arachidyl Alcohol, and Arachidyl Glucoside. Standing selected one, but you can use the least, but is not limited thereto.

The formulations of the cosmetic composition of the present invention are not particularly limited, and may include components of cosmetic compositions commonly used in the art to which the invention belongs according to the formulation to be produced. The cosmetic composition of the present invention can be formulated into, for example, a liquid product, a lotion, an essence, a cream, a sun lotion, a sun cream, a makeup base, a foundation, a baboon cream, a stick- But is not limited thereto. . In addition, oil, water, a surfactant, a moisturizer, a lower alcohol, a thickener, a chelating agent, an antiseptic, a fragrance and the like may be selected and added in accordance with the formulation to be prepared. In addition, the cosmetic composition of the present invention may contain an ultraviolet screening agent, a light scattering agent, etc., and the formulations and the additive components are not limited to the above contents. The components can also be introduced in amounts commonly used in the field of dermatology.

The cosmetic composition according to the present invention improves the complexion and improves the skin's immediate whitening effect by including the calamine. Particularly, the water-in-oil type formulation including the coloramine improves the complexion and the immediate whitening effect of the skin, Is excellent.

The present invention also provides a skin external composition for immediate whitening or complexion improvement comprising calamine.

In the present invention, the calamine may include 10 to 25% by weight based on the total weight of the composition, and may include 15 to 20% by weight based on the total weight of the composition.

The composition for external application for skin of the present invention may be blended with various known components to be blended in a composition applied to skin or mucous membranes. Examples of such components include various additives such as a surfactant, a pH adjuster, a coloring matter, a flavor, a preservative, a bactericide, a thickener, an antioxidant, a sequestering agent for metal ions, , Vitamins, plant extracts, skin astringents, anti-inflammatory agents, cell activators, vasodilators, blood circulation promoters, and skin sensitizers. Depending on the formulation, well-known reagents and carriers may also be used.

Examples of the surfactant include, but are not limited to, anionic surfactants such as higher fatty acid soaps, alkyl sulfate ester salts, polyoxyethylene alkyl ether sulfate, alkyl ether phosphate ester salts, N-acyl amino acid salts and acyl N- Surfactants; Cationic surfactants such as alkyltrimethylammonium chloride and dialkyldimethylammonium chloride; Amphoteric surfactants such as alkyldimethylaminoacetic acid betaine, alkylamido dimethylaminoacetic acid betaine and 2-alkyl-N-carboxy-N-hydroxyimidazolinium betaine; And nonionic surfactants such as polyoxyethylene type, polyhydric alcohol ester type, and ethylene oxide / propylene oxide block copolymer. Further, without limitation, surfactants belonging to polymeric surfactants or natural surfactants can also be used.

The pH regulator may be selected from the group consisting of sodium hydroxide, boric acid, citric acid, alkinoamides, triethanolamine, acetic acid, sodium hydrogencarbonate, phosphoric acid, ammonia water, sodium sulfite, sodium hexametaphosphate, glucono delta lactone, adipic acid, Sodium, and the like, but the present invention is not limited thereto.

Examples of the incrementing agent include hydroxymethylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, carboxyvinylpolymer, alkyl-modified carboxyvinylpolymer, and polyacrylamide ), Sodium alginate, propylene glycol alginate, agar, sodium polyacrylate, succinoglucan, dextran, mannan, pectin Pectin, Gellan Gum, Carrageenan, Hyaluronic acid, Polyvinyl alcohol, Bentonite, Aluminum Silicate, Magnesium Silicate, Laponite Lecithin, laponite, hectorite, silicic acid anhydride, etc. As the metal ion sequestering agent, for example, But are not limited to, sodium ethylenediaminetetraacetic acid, sodium salt, phosphoric acid, and citric acid.

Other preservatives include ethyl parabenzoyl benzoate, salicylic acid, and sorbic acid, for example.

When the formulation is a paste, a cream or a gel, an animal oil, a vegetable oil, a wax, a paraffin, a starch, a tracer, a cellulose derivative, polyethylene glycol, silicon, bentonite, silica, talc or zinc oxide may be used as a carrier component .

When the formulation is a powder or a spray, lactose, talc, silica, aluminum hydroxide, calcium silicate or polyamide powder can be used as a carrier component. In particular, in the case of a spray, a chlorofluorocarbon, Propane, such as butane or dimethyl ether.

When the formulation is a solution or an emulsion, a solvent, a solubilizing agent or an emulsifying agent may be used as a carrier component. Examples of the solvent include water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, -Butyl glycol oil, glycerol aliphatic ester, polyethylene glycol or fatty acid esters of sorbitan.

When the formulation is in the form of a suspension, a carrier, such as water, a liquid diluent such as ethanol or propylene glycol, a suspension such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol ester and polyoxyethylene sorbitan ester, microcrystalline cellulose, Aluminum metahydroxide, bentonite, agar or tracant.

The composition for external application for skin of the present invention may be directly applied to the skin or sprayed depending on its form. The amount of the composition to be used and the number of times of use per day may be appropriately set according to the age, sex, use, severity of symptoms, etc. of the user. For example, an appropriate amount of the composition may be changed from once / day to 5 or 6 times / It can be applied to skin frequently.

The present invention also provides an immediate whitening or facelift improvement method comprising applying a cosmetic composition comprising calamine to the skin.

In the present invention, the calamine may include 10 to 25% by weight based on the total weight of the composition, and may include 15 to 20% by weight based on the total weight of the composition.

The water-in-oil type cosmetic composition containing a calamine according to the present invention has an excellent whitening effect and an improved coloring effect, and has a better moisture holding ability than an underwater type cosmetic composition.

FIG. 1 is a photograph showing the immediate whitening effect (? L *) according to the content of the coloramine in Examples 1 to 8.
Fig. 2 is a photograph comparing the whitening effect and the complexion improving effect of the composition of Example 5 immediately before and after applying the facial face.
Fig. 3 is a photograph showing the result of the 24 hour human stimulation patch test of the composition of Example 5. Fig.

Hereinafter, the present invention will be described in more detail with reference to examples and comparative examples. However, the examples and comparative examples are provided only for the understanding of the present invention, and the scope of the present invention is not limited by these examples and comparative examples in any sense.

Example  1 to 8 and Comparative Example  1-2

In order to confirm the moisturizing effect of the water-in-oil (O / W) formulation, Comparative Example 1 of an underwater type cosmetic formulation was prepared in the composition shown in [Table 1] (unit: wt.%).

In order to confirm immediate whitening, improvement of complexion and moisturizing effect according to the content of calamine in the water-in-oil type (W / O) formulation, Comparative Example 2 of the water-in-oil type cosmetic formulation and Example 1 to 8 (Unit: wt%).

ingredient No. ingredient Comparative Example 1 Oil component One Cetearyl alcohol 0.50 2 Glyceryl stearate 0.25 3 FAGE -100 stearate 0.25 4 Vegetable squalane 3.00 5 Butyleneglycol dicaprylate / dicaprate 2.00 6 Ethylhexyl palmitate 5.00 7 Sheer butter 3.00 8 Dimethicone 0.2 9 Calamine 15.00 Water component 10 Purified water Balance 11 Sodium chloride 1.50 12 Disodium iodide 0.05 13 Bi Osaka Ride Sword-2 1.00 14 glycerin 10.00 15 Polysorbate 60 3.00 16 Carbomer Suitable amount 17 Sodium hydroxide Suitable amount 18 antiseptic Suitable amount 19 Spices Suitable amount Total weight% 100

division No. ingredient Comparative Example 2 Example 1 Example 2 Example 3 Example 4 Example 5 Example 6 Example 7 Example 8 Oil component One Three tilipies / piperazine-10/1 dimethicone 3.00 3.00 3.00 3.00 3.00 3.00 3.00 3.00 3.00 2 Ethylhexyl palmitate 13.00 13.00 13.00 13.00 13.00 13.00 13.00 13.00 13.00 3 Vegetable squalane 7.00 7.00 7.00 7.00 7.00 7.00 7.00 7.00 7.00 4 Ozokerite 2.00 2.00 2.00 2.00 2.00 2.00 2.00 2.00 2.00 5 Calamine - 1.00 5.00 10.00 15.00 18.00 20.00 25.00 30.00 Water component 6 Purified water Balance Balance Balance Balance Balance Balance Balance Balance Balance 7 Sodium chloride 1.50 1.50 1.50 1.50 1.50 1.50 1.50 1.50 1.50 8 Disodium iodide 0.04 0.04 0.04 0.04 0.04 0.04 0.04 0.04 0.04 9 Propanediol 12.00 12.00 12.00 12.00 12.00 12.00 12.00 12.00 12.00 10 Sodium hyaluronate 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 11 By Osaka Ride Sword 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 12 antiseptic Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount 13 Spices Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount Total weight% 100

< Comparative Example  1 &gt;

1) Water phase component No. 1 in Table 1 above. Calamine was mixed and dispersed at 10 to 19 times.

2) The oil component No. 1 in Table 1 above. 1 to 8 were all mixed.

3) The above 2) solution was added to the above 1) solution to emulsify, followed by complete degassing to prepare an underwater type cosmetic composition.

< Comparative Example  2 and Example  Manufacturing method 1 to 8>

1) Calamine was mixed and dispersed in the oil component Nos. 1 to 4 of the above [Table 2].

2) Water component Nos. 6 to 13 in Table 2 were all mixed.

3) The above 2) solution was added to the above 1) solution to emulsify, followed by complete deaeration to prepare a water-in-oil type cosmetic composition.

Test Example  One: Calamine  Depending on the content Instant whitening  effect, Improving complexion  Check effects and moisturizers

Test Example  1-1: Calamine  Depending on the content Instant whitening  Check the effect

The immediate whitening effect of the composition prepared in Comparative Example 2 and Examples 1 to 8 was evaluated in order to confirm an immediate whitening effect according to the content of calamine.

For evaluation of immediate whitening, specifically, in order to examine the change of skin brightness upon application of one time according to the content of calamine, the composition of Comparative Example 2 and Examples 1 to 8 was circulated to three adults and 2 The change in skin brightness was measured using a skin-color meter (CL400 courage Khazaka electronic GmbH, Germany) after applying 30 μl / cm ² . The skin color meter measures the L * value of the skin surface. It measures the brightness of the skin. The skin brightness was measured in advance using a skin color meter at constant temperature and humidity (22 ± 2 ° C, humidity 50 ± 10%) before the application, and the results are shown in Table 3 and FIG.

In addition, in order to examine the change of skin brightness for immediate whitening, the facial part photographing is performed while the external light is blocked by using Visioface (1000D courage Khazaka electronic GmbH, Germany) The photographs were taken based on the same conditions and face positions, and the results are shown in FIG.

<Evaluation criteria for immediate whitening effect>

The L * value, which is the brightness of the skin surface, was measured by dividing the same area of the cheek before and after application because of individual difference and area difference. Before and after application of the measured L * values of the three subjects, the amount of change DELTA L * was derived to confirm the whitening effect immediately.

division Instant whitening effect
(? L * value) Comparative Example 2 0 Example 1 0.20 Example 2 0.41 Example 3 2.50 Example 4 3.17 Example 5 3.94 Example 6 5.16 Example 7 7.04 Example 8 8.79

As a result, as shown in FIG. 1, it was confirmed that the amount of change in brightness increased with an increase in the content of calamine, and thus it was confirmed that the whitening effect was immediately excellent in a concentration-dependent manner depending on the content of calamine.

Further, as shown in Fig. 2, it was confirmed that the whitening effect immediately before and after application of Example 5 was remarkable.

In addition, as shown in Table 3, the immediate whitening effect according to the content of the calamine was increased as the content of the calamine was increased. As a result, in Examples 3 to 8, the whitening effect was more rapid than that in Comparative Example 2 and Examples 1 to 2 Respectively.

Test Example  1-2: Calamine  Depending on the content Improving complexion  Check the effect

In order to confirm the effect of improving the complexion according to the content of the coloramine, the composition of Comparative Example 2 and Examples 1 to 8 was evaluated for improving the complexion.

To evaluate the improvement of the complexion color, in order to evaluate the satisfaction of the complexion improvement of the subject when the composition was applied by one time according to the content of the coloramine, the same amount of the composition of Comparative Example 2 and Examples 1 to 8 was applied to three adults And the satisfaction was surveyed. The results are shown in Table 4 below.

<Evaluation criteria for improvement of complexion>

Sensory evaluation was performed to evaluate the satisfaction of the subjects' complexion improvement. The satisfaction level of the complexion improvement was evaluated as 10 points (1 point, 3 points, 7 points, 10 points), and the improvement effect of the complexion was confirmed.

1 point: Very dissatisfied

3 points: Dissatisfied

7 points: Satisfied

10: Very satisfied

division Improvement of complexion
(Out of 10) Comparative Example 2 0 Example 1 One Example 2 3 Example 3 7 Example 4 10 Example 5 10 Example 6 10 Example 7 7 Example 8 3

As a result, as shown in Table 4, it was confirmed that the compositions of Examples 3 to 7 were more satisfactory than those of the compositions of Examples 4 to 6, with satisfaction of the complexion improvement according to the content of the chromamine. Example 8, which has the best immediate whitening effect, is rather unsatisfactory due to severe whitening.

Test Example  1-3: Calamine  Determination of moisturizing effect by contents

In order to confirm the moisturizing effect according to the calamine content, the moisturizing effect of the composition prepared in Comparative Example 2 and Examples 1 to 8 was evaluated.

Specifically, the compositions of Comparative Example 2 and Examples 1 to 8 were applied to three adult males and females by applying a 2 μl / cm ² coating on a Falabak circle, followed by waiting for 30 minutes, and then, using a corneometer CM825 courage Khazaka electronic GmbH, Germany). The coneometer is a sensor that measures the moisture content of the surface of the skin by static charge capacitance measurement and measures moisture content within 10 μm to 20 μm. The moisture content of the skin was measured in advance by using a coneometer at constant temperature and humidity (22 ± 2 ° C., humidity: 50 ± 10%) before the application, and the results are shown in Table 5.

<Evaluation criteria for moisturizing>

In the case of moisture content, the amount of water before and after application of the armhavumb site was compared because of the large individual difference and site difference. As shown in the following equation (1), the average moisture improvement rate of the three persons was derived to confirm the moisturizing effect. The water content improvement rate is a measure of how much moisture of the skin after application has increased relative to the moisture content of the skin before application.

division Moisturizing effect
(Water content improvement ratio) Comparative Example 2 109.8% Example 1 66.2% Example 2 83.9% Example 3 53.8% Example 4 72.9% Example 5 73.7% Example 6 66.3% Example 7 64.9% Example 8 39.8%

As a result, as shown in Table 5, it was confirmed that the moisturizing effect of Example 8 was the least, and the moisturizing effects of Examples 1 to 7 were all excellent, depending on the content of the calamine.

Test Example  2: Calamin  Included Water type  And moisturizing effect of underwater type formulation

In order to confirm the moisturizing effect of water-in-oil (W / O) and water-in-oil (O / W) formulations containing calamine, in Comparative Examples 1 to 2 of the underwater type formulations and in Examples 1 to 8 of the water- The moisturizing effect of the composition thus prepared was evaluated.

Specifically, in order to evaluate the skin moisturizing ability in one application according to the water-in-water and water-in-water type formulations, the composition of Comparative Examples 1 to 2 and Examples 1 to 8 was applied to three adults 1). The results are shown in Table 6 below.

<Evaluation criteria for moisturizing>

In the case of moisture content, the amount of water before and after application of the armhavumb site was compared because of the large individual difference and site difference. As shown in the following formula (2), the average moisture change was calculated by subtracting the average moisture content before application from the average moisture content after application of three subjects, and the moisturizing effect was confirmed.

division Before application
Average moisture content After application
Average moisture content Moisturizing effect
(Average moisture change amount) Comparative Example 1 24.5 31.1 + 6.6 Comparative Example 2 21.5 44 + 22.5 Example 1 20.7 33.2 + 12.5 Example 2 19.4 35.5 + 16.1 Example 3 20.4 31.2 + 10.8 Example 4 24.8 39.5 + 14.7 Example 5 20.4 32.8 + 12.4 Example 6 23.3 35.2 + 11.9 Example 7 22.0 37.4 + 15.4 Example 8 22.7 30.8 + 8.1

As a result, as shown in Table 6, in the case of the cosmetic composition containing calamine, the water-in-oil type formulation (Comparative Example 2 and Examples 1 to 8), regardless of the content of the calamine, It was confirmed that the moisturizing effect was excellent.

Test Example  3: Calamin  inclusive Water type  Confirming the effect of improving the skin's gloss (shine)

In order to confirm the effect of improving the skin luster of the water-in-oil type (W / O) formulation including the calamine, the effect of improving the skin luster of the composition prepared in Example 5 of the water-in-oil type formulation was evaluated.

To evaluate the improvement of skin gloss, specifically, in order to evaluate the effect of improving the skin gloss upon one-time application in a water-in-oil type formulation containing calamine, the composition of Example 5 was applied to two adult males and 2 females ^{After 2} minutes of application and waiting for 30 minutes, the gloss of the skin was measured using a glossimeter (GL200 courage Khazaka electronic GmbH, Germany). Glossy meter is a sensor for measuring the gloss (shine) of skin surface against reflectance, and measures skin gloss. The skin gloss was measured beforehand using a gloss meter at the temperature of constant temperature and humidity (22 ± 2 ° C., humidity of 50 ± 10%), and the skin gloss was measured as a default. The results are shown in Table 7 below.

&Lt; Evaluation Criteria for Improvement of Skin Gloss >

Since the luster of the skin surface was large and individual differences were large, the same part of the cheeks was measured before application and after application. The average skin gloss improvement ratio after application of two subjects was derived, and skin gloss improvement effect was confirmed.

division Before application
Average skin gloss After application
Average skin gloss Skin gloss improvement effect
(Average improvement rate) Example 5 8.59 13.91 61.93%

As a result, as shown in Table 7, it was confirmed that the water-in-oil type formulation containing the calamine in Example 5 was excellent in improving the skin glossiness (glossiness).

Test Example  4: Calamin  inclusive Water type  Confirm skin irritation of formulation

In order to confirm the skin irritation of the water-in-oil type (W / O) formulation including the calamine, the skin irritation of the composition prepared in Example 5 of the water-in-oil type formulation was evaluated.

To evaluate the skin irritation, a safety evaluation was conducted according to the human body application test to determine the primary stimulation on the skin of the water-in-oil type including calamine. To 20 adult male and female subjects, 20 조성물 of the composition of Example 5 was applied to a flat area such as a vertebra except for the vertebrae for 24 hours, and the skin reaction after 1 hour and 24 hours of elimination of the patch was visually evaluated, The results are shown in FIG. 3 and Table 8 below.

<Evaluation criteria for skin irritation>

The degree of skin reaction was evaluated in 5 steps (0 ~ 4 points), and evaluation values were obtained. Skin response was calculated using the evaluation values. The skin response was calculated as shown in Equation (3) below, and the skin irritation index was calculated using the equation. The skin irritation index was calculated by the following formula (4). Skin irritation index 0.00 to 0.25 is non-irritant, 0.26 to 1.00 is mild irritant, 1.01 to 2.50 is moderate irritant, and 2.51 to 4.00 is irritant.

division Skin irritation index Degree of skin irritation Example 5 0.00 Non-irritant

As a result, as shown in Table 8 and FIG. 3, it was confirmed that the water-in-oil type formulation including the calcium salt of Example 5 was non-magnetic without irritation.

Claims (6)

A water-in-oil type cosmetic composition for immediate whitening and facial color improvement comprising calamine (Calamine) in an amount of 10 to 25% by weight based on the total weight of the composition.
delete delete delete The cosmetic composition according to claim 1, wherein the cosmetic composition is formulated into a liquid product, a lotion, an essence, a cream, a sun lotion, a sunscreen, a makeup base, a foundation, a baboon cream, a stick-shaped product or a night-type product.
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