CN112089744A - Preparation method of medicinal oil, medicinal oil and application of medicinal oil - Google Patents
Preparation method of medicinal oil, medicinal oil and application of medicinal oil Download PDFInfo
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- CN112089744A CN112089744A CN202011062231.7A CN202011062231A CN112089744A CN 112089744 A CN112089744 A CN 112089744A CN 202011062231 A CN202011062231 A CN 202011062231A CN 112089744 A CN112089744 A CN 112089744A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/30—Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/31—Hydrocarbons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/001—Preparations for care of the lips
Abstract
The invention provides a preparation method of medicinal oil and application of the medicinal oil, wherein the preparation method comprises the steps of firstly taking 20-40 parts by weight of lithospermum, 10-20 parts by weight of angelica sinensis and 5-15 parts by weight of centella asiatica, crushing, then soaking in 300-1000 parts by weight of jojoba oil, then preserving heat at 80-100 ℃ and 40-80 ℃, continuously stirring during the heat preservation, and finally collecting filtrate. The medicinal oil can be made into lipstick which comprises the following components in parts by weight: 50-150 parts of squalane, 20-40 parts of jojoba oil, 5-15 parts of shea butter, 20-40 parts of medicinal oil, 15-30 parts of VE, 30-50 parts of jasmine wax and 30-50 parts of candelilla wax. The invention uses the centella to combine the lithospermum and the angelica, and prepares the medicinal oil which is more beneficial to playing the roles of cooling blood, invigorating blood circulation and detoxifying of the lithospermum, enriching and activating blood of the angelica and clearing heat, detoxifying and reducing swelling of the centella.
Description
Technical Field
The invention relates to the technical field of skin care products, in particular to a preparation method of medicinal oil, the medicinal oil and application of the medicinal oil.
Background
The dry cracking of the lips is most common in autumn and winter, and is mainly caused by the decrease of air temperature and dry air, and the dry and water-deficient skin around the lips. The lip chapping needs to be moistened by water, saliva has a certain moistening effect, and a lot of people can involuntarily lick the lips with the tongue to form a 'sausage mouth', so that the tongue licking cheilitis is induced. The lip chap can be improved by improving the ways of eating, drinking more water, using a humidifier, having a mask and the like, and the lip chap can also be improved well by using the lip balm, so that the lip balm is more convenient and practical. However, most of the existing lipsticks with good moistening and anti-chapping effects contain chemical components which are not suitable for being taken in mouth, and are easy to be carelessly eaten after being applied to the belly, so that the body is adversely affected after long-term storage. The book two introduction of the book of surgery syndrome treatment: the lithospermum and the angelica are respectively equally divided, decocted by sesame oil, removed with slag and taken out of fire, and the lithospermum and the angelica are frequently moistened by dipping the oil in cotton. For small bubbles of white skin on the lips, the swollen lips gradually become silkworm cocoon or swollen lips are dark red dates, so the lips are dry, itchy and painful. The oil is commonly called as ZIGUI oil, and is applied by dipping a cotton swab, and the ZIGUI oil has the effects, but the moisture retention and the anti-cracking performance need to be further improved.
Disclosure of Invention
In order to solve the defects of the prior art, the invention provides a preparation method of medicinal oil, the medicinal oil and application of the medicinal oil.
The technical scheme of the invention is as follows:
a preparation method of medicinal oil comprises the following specific operations: taking 20-40 parts by weight of lithospermum, 10-20 parts by weight of angelica sinensis and 5-15 parts by weight of centella asiatica, crushing, adding 300-1000 parts by weight of jojoba oil, soaking for 30-60 min, heating to 80-100 ℃, preserving heat for 5-30 min, preserving heat for 60-120 min at 40-80 ℃, continuously stirring during soaking and heat preservation, filtering and collecting filtrate. Centella asiatica is used as a medicine with whole herbs, is cold in nature, bitter and pungent in taste, has the effects of clearing heat, promoting diuresis, detoxifying and reducing swelling, and is clinically used for damp-heat jaundice, carbuncle sore and pyogenic infections, traumatic injuries and the like. The radix arnebiae and the angelica are matched with the centella to play roles of cooling blood, activating blood and detoxifying by the radix arnebiae, and the angelica enriches the blood and activates the blood and the centella clears heat, detoxifies and reduces swelling.
Preferably, 30 parts by weight of lithospermum, 15 parts by weight of angelica and 10 parts by weight of centella are taken firstly, 500 parts by weight of jojoba oil is added after the lithospermum, the mixture is soaked for 30min, then the mixture is heated to 100 ℃ and kept warm for 5min in a water bath, then the temperature of the mixture is kept warm for 60min in a water bath at 60 ℃, the mixture is continuously stirred during the soaking and the heat preservation, and the filtrate is collected after the filtration to obtain the compound fertilizer.
A medicinal oil is prepared by the above method, and has effects of preventing and treating xerostomia.
A lipstick for preventing and treating xerostomia contains the above medicinal oil.
Preferably, the lipstick comprises the following components in parts by weight: 50-150 parts of squalane, 20-40 parts of jojoba oil, 5-15 parts of shea butter, 20-40 parts of medicinal oil, 15-30 parts of VE, 30-50 parts of jasmine wax and 30-50 parts of candelilla wax.
Further preferably, the lipstick comprises the following components in parts by weight: 80-120 parts of squalane, 25-35 parts of jojoba oil, 8-12 parts of shea butter, 25-40 parts of medicinal oil, 18-25 parts of VE, 35-45 parts of jasmine wax and 35-45 parts of candelilla wax.
The preparation method of the lipstick for preventing and treating lip chapping comprises the following operations: heating jasmine wax and candelilla wax to melt, stirring, adding squalane, jojoba oil, shea butter, medicinal oil and VE, stirring, injecting into lipstick mold, cooling, and demolding.
Preferably, the jasmine wax and the candelilla wax are heated to be molten at 80-95 ℃, stirred at the rotating speed of 5-60 r/min for 5-60 min, added with squalane, jojoba oil, shea butter, medicinal oil and VE, stirred at the rotating speed of 5-60 r/min for 5-60 min, injected into a lipstick mold, cooled and demoulded.
Compared with the prior art, the invention combines the lithospermum and the angelica with the centella, is more favorable for playing the roles of cooling blood, activating blood and detoxifying of the lithospermum, enriching blood and activating blood of the angelica and clearing heat, detoxifying and reducing swelling of the centella, so that the medicinal oil is prepared, and the prepared medicinal oil is mixed with the squash, the jojoba oil, the shea butter, the VE, the jasmine wax and the candelilla wax to prepare the lipstick with good moistening and moisturizing effects.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The materials used in the following examples are all directly commercially available.
Example 1
Preparation of medicinal oil: taking 30g of lithospermum, 15g of angelica and 10g of centella, crushing, adding 500g of jojoba oil, soaking for 30min, heating to 100 ℃, preserving heat in water bath for 5min, preserving heat in water bath at 60 ℃ for 60min, continuously stirring during soaking and heat preservation, and filtering to collect filtrate.
A lipstick for preventing and treating lip chapping comprises the following components in parts by weight: 50g of squalane, 40g of jojoba oil, 5g of shea butter, 40g of medicinal oil, VE15g, 50g of jasmine wax and 30g of candelilla wax, and the preparation method comprises the following steps: heating jasmine wax and candelilla wax at 80-85 deg.C to melt, stirring at 25r/min for 10min, adding squalane, jojoba oil, shea butter, medicinal oil and VE, stirring at 25r/min for 20min, injecting into lipstick mold, cooling, and demolding.
Example 2
Preparation of medicinal oil: pulverizing radix Arnebiae 40g, radix Angelicae sinensis 10g, and herba Centellae 5g, adding oleum Nelumbinis and semen Nelumbinis 300g, soaking for 60min, heating to 80 deg.C, maintaining the temperature in water bath for 30min, maintaining the temperature in water bath at 40 deg.C for 120min, stirring, filtering, and collecting filtrate.
A lipstick for preventing and treating lip chapping comprises the following components in parts by weight: the preparation method comprises the following steps of 80g of squalane, 35g of jojoba oil, 8g of shea butter, 35g of medicinal oil, 18g of VE, 45g of jasmine wax and 35g of candelilla wax, and the preparation method comprises the following steps: heating jasmine wax and candelilla wax at 85-90 ℃ until the jasmine wax and candelilla wax are melted, stirring at the rotation speed of 50r/min for 30min, adding squalane, jojoba oil, shea butter, medicinal oil and VE, stirring at the rotation speed of 40r/min for 40min, injecting into a lipstick mold, cooling, and demolding.
Example 3
Preparation of medicinal oil: taking 20g of lithospermum, 20g of angelica and 15g of centella, crushing, adding 1000g of jojoba oil, soaking for 45min, heating to 90 ℃, preserving heat in water bath for 15min, preserving heat in water bath for 90min at 80 ℃, continuously stirring during soaking and heat preservation, and filtering to collect filtrate.
A lipstick for preventing and treating lip chapping comprises the following components in parts by weight: the preparation method comprises the following steps of (1) 100g of squalane, 30g of jojoba oil, 10g of shea butter, 30g of medicinal oil, 20g of VE, 40g of jasmine wax and 40g of candelilla wax, and the preparation method comprises the following steps: heating jasmine wax and candelilla wax at 85-90 ℃ until the jasmine wax and candelilla wax are melted, stirring at the rotating speed of 40r/min for 40min, adding squalane, jojoba oil, shea butter, medicinal oil and VE, stirring at the rotating speed of 30r/min for 30min, injecting into a lipstick mold, cooling, and demolding.
Example 4
The preparation method of the medicinal oil is the same as that of example 1.
A lipstick for preventing and treating lip chapping comprises the following components in parts by weight: 120g of squalane, 25g of jojoba oil, 12g of shea butter, 25g of medicinal oil, 25g of VE, 35g of jasmine wax and 45g of candelilla wax, and the preparation method comprises the following steps: heating jasmine wax and candelilla wax at 90-95 ℃ until the jasmine wax and candelilla wax are melted, stirring at the rotating speed of 5r/min for 60min, adding squalane, jojoba oil, shea butter, medicinal oil and VE, stirring at the rotating speed of 60r/min for 5min, injecting into a lipstick mold, cooling, and demolding.
Example 5
The preparation method of the medicinal oil is the same as that of example 1.
A lipstick for preventing and treating lip chapping comprises the following components in parts by weight: 150g of squalane, 20g of jojoba oil, 15g of shea butter, 20g of medicinal oil, 30g of VE, 30g of jasmine wax and 50g of candelilla wax, and the preparation method comprises the following steps: heating jasmine wax and candelilla wax at 90-95 ℃ until the jasmine wax and candelilla wax are melted, stirring at the rotation speed of 60r/min for 5min, adding squalane, jojoba oil, shea butter, medicinal oil and VE, stirring at the rotation speed of 5r/min for 60min, injecting into a lipstick mold, cooling, and demolding.
The lipsticks prepared in the embodiments 1 to 5 of the invention are light purple, the cream is fine and smooth, the spreadability is good, the smell is elegant, and the hardness and the viscosity are moderate; the cold and hot stability is good, no layering exists after the paste is refrigerated for 10 days in a refrigerator at the temperature of 5 ℃, no layering and no peculiar smell occur after the paste is kept stand for 6 months at room temperature, the visual feeling is unchanged during use, and the paste is not melted, layered and smellless after the paste is placed in a constant temperature box at the temperature of 50 ℃ for 1 week. The lipsticks prepared in examples 1-5 were not delaminated after being refrigerated in a refrigerator at 5 ℃ for 10 days, allowed to stand at room temperature for 6 months, and placed in a thermostat at 50 ℃ for 1 week, and then centrifuged at 3000-.
The lipstick prepared in examples 1 to 5 was tried by selecting 50 subjects (between 16 and 30 years old, with no limitation on the nature, no other lipstick, etc. should be used on the same day of the test) and dividing into 5 groups and 10 subjects. Before the test, the test is performed after the test subject sits still for 30min at the room temperature of 20 +/-2 ℃ and the relative humidity of 50% +/-5%.
1. Heme content test
Inflammation can cause redness and swelling and lead to increased hemoglobin content. The lipsticks prepared in examples 1-5 were applied to the forehead, left cheek and right cheek of the subject, respectively, and visually observed to show that: the red and swollen part of each subject before the test is reduced or even disappears after the application. The face of the subject of example 1 was photographed using the VISIA facial image analysis system (front and left and right 45 ° directions), the change in hemoglobin content before and after use was analyzed and compared, and the change in hemoglobin content was calculated by performing image analysis on the test photograph using software IPP7.0C. The test results are shown in fig. 1: after the test, the heme content of three different parts (forehead, left cheek and right cheek) of the face of the subject is reduced, so that the lipstick prepared by the invention can obviously reduce red swelling, red blood streak and other phenomena caused by inflammation.
2. Skin texture test
The lips dry out causing a deepening and increasing of the texture. The lipsticks prepared in examples 1 to 5 were applied to the lips of the subjects, respectively, and observed with naked eyes: after a period of application, the lip cracks of each subject became light. The face of the subject of example 1 was photographed (obverse) with the VISIA facial image analysis system for 0min, 10min, and 30min for each smear sample, and the texture conditions before and after use were analyzed and compared, and the change in the number and area of the texture was calculated by analyzing the image of the test photograph with the IPP7.0C software. The test results are shown in fig. 2 and 3: after the test, the number of the textures on the surface of the lip of the tested person is obviously reduced and the area of the textures is obviously reduced after the lip is smeared for 10min and 30min, so that the phenomena of increased textures and increased area caused by lip chapping can be obviously reduced by the lipstick prepared by the invention.
3. Skin moisture content test
The lipstick prepared in example 1 was applied to the lips of the subjects, and observed with naked eyes: after application, the lips of each subject became very moist. The moisture content of the lips before and after application of the subject of example 1 was tested using an MPA10 skin moisture meter (CK, germany). The test results are shown in fig. 4: after the lipstick is applied, the moisture content of the lips is obviously increased, so that the lipstick prepared by the lipstick provided by the invention can obviously improve the dryness of the lips.
The above 3 tests are combined to show that: the lipstick prepared by the self-made medicinal oil can obviously reduce the content of heme in skin, reduce the quantity and area of skin textures, increase lip moisture, and has obvious effects on relieving skin inflammation, lightening lip textures, supplementing moisture and the like.
The invention is not to be considered as limited to the particular embodiments shown and described, but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.
Claims (9)
1. The preparation method of the medicinal oil is characterized by comprising the following steps: the specific operation is as follows: taking 20-40 parts by weight of lithospermum, 10-20 parts by weight of angelica sinensis and 5-15 parts by weight of centella asiatica, crushing, adding 300-1000 parts by weight of jojoba oil, soaking for 30-60 min, heating to 80-100 ℃, preserving heat for 5-30 min, preserving heat for 60-120 min at 40-80 ℃, continuously stirring during soaking and heat preservation, filtering and collecting filtrate.
2. The method for preparing the medicinal oil according to claim 1, which is characterized in that: the specific operation is as follows: firstly, 30 parts by weight of lithospermum, 15 parts by weight of angelica and 10 parts by weight of centella asiatica are taken, 500 parts by weight of jojoba oil is added after the lithospermum, the angelica and the centella asiatica are crushed and soaked for 30min, then the temperature is heated to 100 ℃ and kept for 5min in a water bath, the temperature is kept for 60min in a water bath at 60 ℃, the components are continuously stirred during the soaking and the heat preservation, and the filtrate is collected after.
3. A medicinal oil obtained by the method of claim 1 or 2.
4. The use of the medicinal oil according to claim 3 for preventing and treating lip dryness.
5. A lipstick for preventing lip chapping is characterized in that: the lipstick comprising the medicinal oil of claim 3.
6. The lipstick for preventing lip dryness according to claim 5, wherein: the lipstick comprises the following components in parts by weight: 50-150 parts of squalane, 20-40 parts of jojoba oil, 5-15 parts of shea butter, 20-40 parts of medicinal oil, 15-30 parts of VE, 30-50 parts of jasmine wax and 30-50 parts of candelilla wax.
7. The lipstick for preventing lip dryness according to claim 6, wherein: the lipstick comprises the following components in parts by weight: 80-120 parts of squalane, 25-35 parts of jojoba oil, 8-12 parts of shea butter, 25-40 parts of medicinal oil, 18-25 parts of VE, 35-45 parts of jasmine wax and 35-45 parts of candelilla wax.
8. A method of preparing the lipstick for preventing lip dryness according to claim 6, wherein: the method comprises the following operations: heating jasmine wax and candelilla wax to melt, stirring, adding squalane, jojoba oil, shea butter, medicinal oil and VE, stirring, injecting into lipstick mold, cooling, and demolding.
9. The method of preparing a lipstick for preventing lip dryness according to claim 8, wherein: the method comprises the following operations: heating jasmine wax and candelilla wax at 80-95 ℃ until the jasmine wax and candelilla wax are melted, stirring at the rotating speed of 5-60 r/min for 5-60 min, adding squalane, jojoba oil, shea butter, medicinal oil and VE, stirring at the rotating speed of 5-60 r/min for 5-60 min again, injecting into a lipstick mold, cooling, and demolding.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011062231.7A CN112089744A (en) | 2020-09-30 | 2020-09-30 | Preparation method of medicinal oil, medicinal oil and application of medicinal oil |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202011062231.7A CN112089744A (en) | 2020-09-30 | 2020-09-30 | Preparation method of medicinal oil, medicinal oil and application of medicinal oil |
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| CN112089744A true CN112089744A (en) | 2020-12-18 |
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| CN202011062231.7A Pending CN112089744A (en) | 2020-09-30 | 2020-09-30 | Preparation method of medicinal oil, medicinal oil and application of medicinal oil |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120308500A1 (en) * | 2011-05-13 | 2012-12-06 | Mary Kay, Inc. | Lip stick |
| CN110025554A (en) * | 2019-05-31 | 2019-07-19 | 长春师范大学 | Pure natural moist lip gloss of one kind and preparation method thereof |
-
2020
- 2020-09-30 CN CN202011062231.7A patent/CN112089744A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120308500A1 (en) * | 2011-05-13 | 2012-12-06 | Mary Kay, Inc. | Lip stick |
| CN110025554A (en) * | 2019-05-31 | 2019-07-19 | 长春师范大学 | Pure natural moist lip gloss of one kind and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 孙世发等: "《中医外科处方手册》", 30 November 2005, 科学技术文献出版社 * |
| 杨丹等: "《桂北药用植物资源现代研究》", 31 May 2019, 河海大学出版社 * |
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