CN112033779A - Operation table for liquid-based thin-layer cell sheet-making machine - Google Patents
Operation table for liquid-based thin-layer cell sheet-making machine Download PDFInfo
- Publication number
- CN112033779A CN112033779A CN202010966197.XA CN202010966197A CN112033779A CN 112033779 A CN112033779 A CN 112033779A CN 202010966197 A CN202010966197 A CN 202010966197A CN 112033779 A CN112033779 A CN 112033779A
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- China
- Prior art keywords
- experiment cabinet
- experiment
- cabinet
- pelleter
- liquid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 239000007788 liquid Substances 0.000 title claims abstract description 29
- 238000002474 experimental method Methods 0.000 claims abstract description 62
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 47
- 239000002699 waste material Substances 0.000 claims abstract description 15
- 239000011521 glass Substances 0.000 claims abstract description 11
- 238000010438 heat treatment Methods 0.000 claims abstract description 11
- 238000009413 insulation Methods 0.000 claims description 14
- 238000000034 method Methods 0.000 abstract description 11
- 230000008569 process Effects 0.000 abstract description 11
- 239000011550 stock solution Substances 0.000 abstract description 8
- 238000004321 preservation Methods 0.000 abstract description 6
- 230000010355 oscillation Effects 0.000 abstract description 3
- 230000008859 change Effects 0.000 abstract description 2
- 238000012864 cross contamination Methods 0.000 abstract description 2
- 230000007613 environmental effect Effects 0.000 abstract description 2
- 210000004027 cell Anatomy 0.000 description 24
- 239000010410 layer Substances 0.000 description 13
- 238000012360 testing method Methods 0.000 description 13
- 230000002380 cytological effect Effects 0.000 description 4
- 238000010586 diagram Methods 0.000 description 4
- 238000012545 processing Methods 0.000 description 3
- 238000005119 centrifugation Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 210000003104 cytoplasmic structure Anatomy 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 210000003097 mucus Anatomy 0.000 description 1
- 239000002356 single layer Substances 0.000 description 1
- 230000007480 spreading Effects 0.000 description 1
- 238000003892 spreading Methods 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/02—Water baths; Sand baths; Air baths
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/02—Laboratory benches or tables; Fittings therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/06—Test-tube stands; Test-tube holders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
- G01N2001/2846—Cytocentrifuge method
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The invention discloses an operating platform for a liquid-based thin-layer cell pelleter, which comprises a working box, wherein a first experiment cabinet, a second experiment cabinet and a third experiment cabinet are arranged on the inner side of the working box, the first experiment cabinet and the third experiment cabinet are positioned on the left side and the right side of the second experiment cabinet, a pelleter is arranged on the inner side of the first experiment cabinet, a centrifugal machine is arranged on the inner side of the second experiment cabinet, stock solution can be stored in a constant-temperature environment in the heat preservation box through arranging a water bath box, a heating plate, a temperature sensor, a water pipe, a water pump and a water tank, so that the stock solution can be prevented from changing due to the change of environmental temperature and influencing a smear, the three processes of oscillation, centrifugal pelleter and observation glass are all in a closed sterile environment through arranging the first experiment cabinet, the second experiment cabinet, the third experiment cabinet and the observation glass, cross contamination is avoided, the observation glass can directly observe the inner experiment process, and through, waste in the experimental process can be properly treated, and concentrated treatment is carried out after the experiment is finished.
Description
Technical Field
The invention relates to the technical field of operation tables, in particular to an operation table for a liquid-based thin-layer cell pelleter.
Background
The cytological smear making process is based on liquid-based cytological principle and includes cell dispersing, filtering, collecting and transferring collected cytological sample, filtering film cylinder driven by rotating mechanism to mix the cytological sample softly, pneumatic and fluid dynamic system controlled by computer for cell collecting, biochemical principle to adsorb the collected cells onto the glass slide naturally to reach perfect cell transfer and homogeneous single layer spreading, and treating with treating liquid to eliminate mucus, blood, etc. in the sample to result in clean background, meanwhile, the flaking process is always in a liquid environment, so that the integrity of cells is preserved, and the nuclear and cytoplasmic structures in the cells are clearer.
The cell living environment is harsh, if the temperature in a laboratory is not proper, cells can be changed abnormally, in the process of preparing the tablet, the cells are not suitable to contact air, stock solution is easy to be polluted, the final experiment result is influenced, waste liquid can not be treated at will, and the waste liquid needs to be collected properly and destroyed in a centralized manner.
Disclosure of Invention
The invention aims to solve the problems of improper stock solution storage, insufficient sealing of experimental environment and difficult waste liquid collection in the prior art, and provides an operating platform for a liquid-based thin-layer cell pelleter, which has the effects of heat preservation, sealing test and waste material collection.
In order to achieve the purpose, the invention provides the following technical scheme: an operation table for a liquid-based thin-layer cell pelleter comprises a working box, wherein a first experiment cabinet, a second experiment cabinet and a third experiment cabinet are arranged on the inner side of the working box, the first experiment cabinet and the third experiment cabinet are positioned on the left side and the right side of the second experiment cabinet, a pelleter is arranged on the inner side of the first experiment cabinet, a centrifugal machine is arranged on the inner side of the second experiment cabinet, an oscillating machine is arranged on the inner side of the third experiment cabinet, a physicochemical table is fixedly connected to the bottom of the working box, a control table is arranged at the top of the physicochemical table, a rubber sleeve is fixedly connected to the bottom of the physicochemical table, an insulation box and a waste box are arranged on the inner side of the physicochemical table, a water bath box, a temperature sensor and a heating plate are arranged on the inner side of the insulation box, the heating plate is electrically connected with the control table, a test tube is slidably connected to the inner side of the, the electronic valve is electrically connected with the control console, the other end of the water pipe is fixedly connected with the water pump, and the water pump is positioned on the inner side of the water tank.
Preferably, the type of the oscillator is KJ202, and the oscillator is electrically connected with the console.
Preferably, the centrifuge model is H1650, centrifuge and control cabinet electric connection.
Preferably, the type of the pelleter is EPS-L1200, and the pelleter is electrically connected with the console.
Preferably, the temperature sensor is of a type DS18B20, and the temperature sensor is electrically connected with the console.
Preferably, the outer sides of the first experiment cabinet, the second experiment cabinet and the third experiment cabinet are all provided with observation glass.
Preferably, the inside of the waste bin and the pelleter are connected by a pipe.
Compared with the prior art, the invention provides an operation table for a liquid-based thin-layer cell pelleter, which has the following beneficial effects:
1. according to the invention, by arranging the water bath box, the heating plate, the temperature sensor, the water pipe, the water pump and the water tank, a stock solution can be stored in a constant temperature environment in the heat preservation box, so that cells are prevented from being changed and affecting a smear due to change of environmental temperature, and by arranging the first experiment cabinet, the second experiment cabinet, the third experiment cabinet and the observation glass, three processes of oscillation, centrifugation and sheet production are all in a closed sterile environment, so that cross contamination is avoided, the observation glass can directly observe an internal experiment process, waste in the experiment process can be properly treated by arranging the waste box, and the waste is treated in a centralized manner after all experiments are finished;
2. the operation table is integrally fixed by arranging the rubber sleeve, and has a shockproof effect, the reagent cannot topple over when stored in the heat preservation box by arranging the test tube rack, and water is prevented from flowing back to the water return box by arranging the electronic valve;
the device has the advantages that the structure is scientific and reasonable, the use is safe and convenient, and great help is provided for people.
Drawings
FIG. 1 is a perspective view of an operation table for a liquid-based thin-layer cell pelleter according to the present invention;
FIG. 2 is a front view of a console for a liquid-based thin-layer cell pelleter according to the present invention;
FIG. 3 is a cross-sectional view of a console for a liquid-based thin-layer cell pelleter according to the present invention;
FIG. 4 is a schematic structural diagram of a centrifuge in a console for a liquid-based thin-layer cell pelleter according to the present invention;
FIG. 5 is a schematic structural diagram of a shaker in an operation console for a liquid-based thin-layer cell pelleter according to the present invention;
FIG. 6 is a schematic structural diagram of a pelleter in an operating console for a liquid-based thin-layer cell pelleter according to the present invention;
FIG. 7 is a schematic structural diagram of an incubator in a console of a liquid-based thin-layer cell pelleter according to the present invention.
Description of the reference numerals
1. A work box; 2. a physical and chemical desk; 3. a rubber sleeve; 4. a heat preservation box; 5. a waste bin; 6. a console; 7. a first laboratory cabinet; 8. observing glass; 9. a second laboratory cabinet; 10. a third experimental cabinet; 11. a water pipe; 12. a water tank; 13. a water pump; 14. a centrifuge; 15. an oscillator; 16. a test tube rack; 17. a water bath tank; 18. a temperature sensor; 19. a heating plate; 20. a sheet making machine; 21. an electronic valve.
Detailed Description
The following detailed description of embodiments of the invention refers to the accompanying drawings. It should be understood that the detailed description and specific examples, while indicating the present invention, are given by way of illustration and explanation only, not limitation.
In the description of the present invention, it should be noted that the terms "upper", "lower", "inner", "outer", "front", "rear", "both ends", "one end", "the other end", and the like indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience of description and simplicity of description, but do not indicate or imply that the referred device or element must have a specific orientation, be constructed in a specific orientation, and be operated, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first" and "second" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
In the description of the present invention, it is to be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "disposed," "connected," and the like are to be construed broadly, and for example, "connected" may be a fixed connection, a detachable connection, or an integral connection; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.
Referring to fig. 1-7, the present invention provides a technical solution: an operation table for a liquid-based thin-layer cell pelleter comprises a work box 1, wherein a first experiment cabinet 7, a second experiment cabinet 9 and a third experiment cabinet 10 are arranged on the inner side of the work box 1, the first experiment cabinet 7 and the third experiment cabinet 10 are positioned on the left side and the right side of the second experiment cabinet 9, a pelleter 20 is arranged on the inner side of the first experiment cabinet 7, a centrifugal machine 14 is arranged on the inner side of the second experiment cabinet 9, an oscillating machine 15 is arranged on the inner side of the third experiment cabinet 10, a physicochemical table 2 is fixedly connected to the bottom of the work box 1, a control table 6 is arranged on the top of the physicochemical table 2 and used for operating all instruments of the operation table, a rubber sleeve 3 is fixedly connected to the bottom of the physicochemical table 2 and used for preventing vibration, an insulation box 4 and a waste box 5 are arranged on the inner side of the physicochemical table 2, a water bath box 17, a temperature sensor 18 and a heating, the inboard sliding connection of water bath 17 has test-tube rack 16, is convenient for file the test tube, and insulation can 4 one side fixedly connected with water pipe 11, and the one end of water pipe 11 is located the insulation can 4 outside and is provided with electronic valve 21, and electronic valve 21 and 6 electric connection of control cabinet prevent water refluence return water tank 12 in, the water pipe 11 other end and water pump 13 fixed connection, and water pump 13 is located water tank 12 inboardly, can go into insulation can 4 with the water pump.
In the invention, preferably, the model of the oscillator 15 is KJ202, the oscillator 15 is electrically connected with the control console 6 and is used for processing stock solution, the model of the centrifuge 14 is H1650, the centrifuge 14 is electrically connected with the control console 6 and is used for processing stock solution, the model of the sheet making machine 20 is EPS-L1200, the sheet making machine 20 is electrically connected with the control console 6 and is used for automatically making sheets, the model of the temperature sensor 18 is DS18B20, the temperature sensor 18 is electrically connected with the control console 6 and is used for controlling the temperature in the heat insulation box, the outer sides of the first experiment cabinet 7, the second experiment cabinet 9 and the third experiment cabinet 10 are respectively provided with observation glasses 8 so as to facilitate observation of an experiment process, the inner side of the waste box 5 is connected with the sheet making machine 20 through a pipeline, and residual waste liquid is directly discharged.
The working principle and the using process of the invention are as follows: when in use, a sampled and numbered cell preservation liquid bottle is placed on a test tube rack 16 in a water bath box 17 in an insulation box 4, an electronic valve 21 is opened on a control console 6, a water pump 13 in a water box 12 is opened, water is pumped into the insulation box 4 through a water pipe 11, the water pump 13 and the electronic valve are operated and closed on the control console 6 after the water is added, a heating sheet 19 is started, a temperature sensor 18 is set on the control console 6 to store the temperature of 37 ℃, when the temperature difference in the insulation box 4 is overlarge, the control console automatically alarms, when the water temperature reaches 37 ℃, the heating sheet 19 is closed, when the water temperature is lower than 37 ℃, the heating sheet is started, so that the unexperienced stock solution is properly stored, one bottle to be tested is taken out according to the number and poured into a clean test tube, then a third experiment cabinet 10 is opened, the test tube is put into an oscillator 15 in the third experiment cabinet 10, the control console 6 starts a machine to start oscillation, the test tube is taken out after the vibration finishes, open second experiment cabinet 9, place the test tube on centrifuge 14, start centrifuge 14 at control cabinet 6, take out the test tube after the centrifugation finishes, and pour the supernatant rapidly in dustbin 5, put the test tube on oscillator 15, oscillate once more, after the vibration finishes, open first experiment cabinet 7, put into pelleter 20 with the test tube, and put into pelleter 20 glass slide with the preliminary treatment slide, open the instrument at control cabinet 6, pelleter 20 accomplishes the film-making, and directly discharge the discarded object in dustbin 5 through the pipeline, so that centralized processing.
The preferred embodiments of the present invention have been described above in detail, but the present invention is not limited thereto. Within the scope of the technical idea of the invention, many simple modifications can be made to the technical solution of the invention, including combinations of various technical features in any other suitable way, and these simple modifications and combinations should also be regarded as the disclosure of the invention, and all fall within the scope of the invention.
Claims (7)
1. The utility model provides a liquid-based thin-layer cell pelleter is with operation panel, includes work box (1), its characterized in that: the utility model discloses a biochemical experiment device, including work box (1), first experiment cabinet (7), second experiment cabinet (9) and third experiment cabinet (10) are provided with to the inboard of work box (1), first experiment cabinet (7) and third experiment cabinet (10) are located the second experiment cabinet (9) left and right sides, first experiment cabinet (7) inboard is provided with pelleter (20), second experiment cabinet (9) inboard is provided with centrifuge (14), third experiment cabinet (10) inboard is provided with shaker (15), work box (1) bottom fixed connection has physicochemical table (2), physicochemical table (2) top is provided with control cabinet (6), physicochemical table (2) bottom fixed connection has rubber sleeve (3), physicochemical table (2) inboard is provided with insulation can (4) and dustbin (5), insulation can (4) inboard is provided with water bath (17), temperature sensor (18) and heating plate (19), heating plate (19) and control cabinet (6) electric connection, water bath (17) inboard sliding connection has test-tube rack (16), insulation can (4) one side fixedly connected with water pipe (11), the one end of water pipe (11) is located insulation can (4) outside and is provided with electronic valve (21), electronic valve (21) and control cabinet (6) electric connection, water pipe (11) other end and water pump (13) fixed connection, water pump (13) are located water tank (12) inboardly.
2. The console for liquid-based thin-layer cell pelleter according to claim 1, wherein the shaker (15) is of type KJ202, and the shaker (15) is electrically connected with the console (6).
3. The console of claim 1, wherein the centrifuge (14) is of type H1650, and the centrifuge (14) is electrically connected to the console (6).
4. The console for a liquid-based thin-layer cell pelleter according to claim 1, wherein the pelleter (20) is of EPS-L1200 type, and the pelleter (20) is electrically connected with the console (6).
5. The console for liquid-based thin-layer cell pelleter according to claim 1, wherein the temperature sensor (18) is of type DS18B20, and the temperature sensor (18) is electrically connected with the console (6).
6. The operating platform for the liquid-based thin-layer cell pelleter according to claim 1, wherein the first experiment cabinet (7), the second experiment cabinet (9) and the third experiment cabinet (10) are provided with observation glasses (8) at the outer sides.
7. Station for a liquid-based thin-layer cell pelleter according to claim 1, characterized in that the inside of the waste tank (5) and the pelleter (20) are connected by a pipe.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010966197.XA CN112033779A (en) | 2020-09-15 | 2020-09-15 | Operation table for liquid-based thin-layer cell sheet-making machine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010966197.XA CN112033779A (en) | 2020-09-15 | 2020-09-15 | Operation table for liquid-based thin-layer cell sheet-making machine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN112033779A true CN112033779A (en) | 2020-12-04 |
Family
ID=73589360
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010966197.XA Pending CN112033779A (en) | 2020-09-15 | 2020-09-15 | Operation table for liquid-based thin-layer cell sheet-making machine |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN112033779A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113731523A (en) * | 2021-09-23 | 2021-12-03 | 潢川县鹏升畜产品有限公司 | Experiment table for extracting heparin sodium crude product |
-
2020
- 2020-09-15 CN CN202010966197.XA patent/CN112033779A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113731523A (en) * | 2021-09-23 | 2021-12-03 | 潢川县鹏升畜产品有限公司 | Experiment table for extracting heparin sodium crude product |
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| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20201204 |
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| WD01 | Invention patent application deemed withdrawn after publication |