CN112022953A - Traditional Chinese medicine composition for clearing intestines and stomach and expelling toxin and preparation method thereof - Google Patents
Traditional Chinese medicine composition for clearing intestines and stomach and expelling toxin and preparation method thereof Download PDFInfo
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Abstract
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for clearing intestines and stomach and expelling toxin and a preparation method thereof; comprises a first component and a second component, wherein the first component comprises: 10-12 parts of angelica sinensis, 8-10 parts of peach kernel, 10-14 parts of morinda officinalis, 10-14 parts of codonopsis pilosula, 10-12 parts of fructus cannabis, 10-12 parts of trichosanthes kirilowii maxim, 10-14 parts of thunberg dwarf lilyturf tuber, 8-12 parts of almond, 10-14 parts of radix rehmanniae, 3-5 parts of safflower, 5-7 parts of cimicifugae foetidae, 8-12 parts of bighead atractylodes rhizome and 5-9 parts of fructus aurantii: the invention has the functions of detoxification, intestine moistening and bowel relaxing, and has better curative effect on various gastrointestinal diseases. It can be used for treating constipation and various speckle, acne, and chloasma caused by long-term constipation. Has obvious curative effect on enteritis and gastritis with symptoms of flatulence, pain in qi, dry and yellow face, poor diet and the like caused by disordered qi and blood due to gastrointestinal dysfunction. The invention is prepared from pure traditional Chinese medicines, is convenient to use, safe and reliable, and has no toxic or side effect. Can be used for a long time.
Description
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for clearing intestines and stomach and expelling toxin and a preparation method thereof.
Background
The stomach is a major organ of the human body and plays an important role in human health. Interior channel is said: it is considered as original and accepted by the abdomen, receiving water and food, purging dregs and qi, ascending and descending the clear and turbid, and ending up the life and ears of the people. Modern people have frequent stomach and intestine diseases due to the reasons of over-fine living diet, reduced exercise amount, overeating or overstrain, gradual decline of human metabolic function, reduced intestinal tract peristalsis, reduced intestinal tract liquid secretion, reduced abdominal muscle contraction force and the like; when the wastes and residues in the body can not be discharged in time, the wastes and residues are decayed and fermented to form stubborn stool, which causes constipation, and feces poison enters blood to cause rough skin and lusterless complexion, and spots, acne, pimples, chloasma and the like are easy to appear on the face. The oil in the intestinal tract can not be discharged out of the body in time, so that the phenomenon of fat intestine is formed. Long-term constipation may induce intestinal cancer, which seriously affects the quality of life and harms the health of people. With the improvement of living standard of people, the aging of social population, the acceleration of the rhythm of life and work of people, the incidence rate of gastrointestinal diseases tends to increase year by year, and the diseased age tends to be younger. Western medicines are adopted to treat the diseases, the side effect is great, and the traditional Chinese medicines are used for expelling toxin and moistening the intestines to achieve a better curative effect.
Disclosure of Invention
In order to solve the technical problems, the invention provides a traditional Chinese medicine composition for clearing intestines and stomach and expelling toxin,
the invention is realized by the following steps:
a traditional Chinese medicine composition for clearing intestines and stomach and expelling toxin comprises a first component and a second component, wherein the first component comprises:
10-12 parts of angelica sinensis, 8-10 parts of peach kernel, 10-14 parts of morinda officinalis, 10-14 parts of codonopsis pilosula, 10-12 parts of fructus cannabis, 10-12 parts of trichosanthes kirilowii maxim, 10-14 parts of thunberg dwarf lilyturf tuber, 8-12 parts of almond, 10-14 parts of radix rehmanniae, 3-5 parts of safflower, 5-7 parts of cimicifugae foetidae, 8-12 parts of bighead atractylodes rhizome and 5-9 parts of fructus aurantii.
Furthermore, the second component comprises 2-4 parts of egg oil.
Further, the first component comprises 10-12 parts of angelica sinensis, 8-10 parts of peach kernel, 11-14 parts of morinda officinalis, 11-14 parts of codonopsis pilosula, 10-12 parts of fructus cannabis, 10-12 parts of trichosanthes kirilowii maxim, 11-14 parts of thunberg dwarf lilyturf tuber, 9-12 parts of almond, 11-14 parts of radix rehmanniae, 3-5 parts of safflower, 5-7 parts of rhizoma cimicifugae, 9-12 parts of bighead atractylodes rhizome and 6-9 parts of fructus aurantii, and the second component comprises 2-4 parts of egg yolk oil.
Further, the first component comprises 10-12 parts of angelica sinensis, 8-10 parts of peach kernel, 11-13 parts of morinda officinalis, 11-13 parts of codonopsis pilosula, 10-12 parts of fructus cannabis, 10-12 parts of trichosanthes kirilowii maxim, 11-13 parts of thunberg dwarf lilyturf tuber, 9-11 parts of almond, 11-13 parts of radix rehmanniae, 3-5 parts of safflower, 5-7 parts of rhizoma cimicifugae, 9-11 parts of bighead atractylodes rhizome and 6-8 parts of fructus aurantii, and the second component comprises 5-7 parts of egg yolk oil.
Further, the first component comprises 10 parts of Chinese angelica, 8 parts of peach kernel, 10 parts of morinda officinalis, 10 parts of codonopsis pilosula, 10 parts of fructus cannabis, 10 parts of trichosanthes kirilowii maxim, 10 parts of Zhejiang ophiopogon root, 8 parts of almond, 10 parts of radix rehmanniae, 3 parts of safflower, 5 parts of rhizoma cimicifugae, 8 parts of bighead atractylodes rhizome and 5 parts of fructus aurantii, and the second component comprises 2 parts of egg yolk oil.
Further, the first component comprises 11 parts of Chinese angelica, 9 parts of peach kernel, 12 parts of morinda officinalis, 12 parts of codonopsis pilosula, 11 parts of fructus cannabis, 11 parts of trichosanthes kirilowii maxim, 12 parts of radix ophiopogonis, 10 parts of almond, 12 parts of radix rehmanniae, 4 parts of safflower, 6 parts of rhizoma cimicifugae, 10 parts of bighead atractylodes rhizome and 7 parts of fructus aurantii, and the second component comprises 3 parts of egg yolk oil.
Further, the first component comprises 12 parts of angelica sinensis, 10 parts of peach kernel, 14 parts of morinda officinalis, 14 parts of codonopsis pilosula, 12 parts of fructus cannabis, 12 parts of trichosanthes kirilowii maxim, 14 parts of thunberg dwarf lilyturf tuber, 12 parts of almond, 14 parts of radix rehmanniae, 5 parts of safflower, 7 parts of cimicifugae foetidae, 12 parts of rhizoma atractylodis macrocephalae and 9 parts of fructus aurantii, and the second component comprises 4 parts of egg yolk oil.
The invention also provides a preparation method of the traditional Chinese medicine composition for clearing intestines and stomach and expelling toxin,
mixing the first components, crushing, heating, steaming the first mixture after heat treatment, fermenting to obtain a first composition, soaking the first composition to obtain a first filtrate, extracting the first filtrate, and adding the second component.
Further, the heating treatment comprises cooking, wherein the cooking time is 10-15 min; the extraction method of the first filtrate comprises reduced pressure evaporation to dryness.
Further, the reduced pressure evaporation drying condition is that the negative pressure is 0.08pa, and the temperature is 55-60 ℃.
The beneficial effect of above-mentioned scheme:
the invention has the functions of detoxification, intestine moistening and bowel relaxing, and has better curative effect on various gastrointestinal diseases. It can be used for treating constipation and various speckle, acne, and chloasma caused by long-term constipation. Has obvious curative effect on enteritis and gastritis with symptoms of flatulence, pain in qi, dry and yellow face, poor diet and the like caused by disordered qi and blood due to gastrointestinal dysfunction. The invention is prepared from pure traditional Chinese medicines, is convenient to use, safe and reliable, and has no toxic or side effect. Can be used for a long time.
The invention adopts the advanced technology, and optimizes and improves the traditional decoction process according to the property characteristics of the active ingredients of the raw material medicines. A great deal of experimental research has been conducted on the selection of the type and amount of enzyme. Finally obtaining the preparation method and the tablets prepared by the method. The method purifies the extract, and the obtained extract (extractum) is remarkably improved compared with the traditional method under the condition of reducing a large amount of impurities, the effective components are stable compared with the original traditional process, the curative effect is remarkably improved compared with the traditional process, and the production cost is greatly reduced.
Detailed Description
The present invention is described in further detail below with reference to specific embodiments.
A traditional Chinese medicine composition for clearing intestines and stomach and expelling toxin comprises a first component and a second component, wherein the first component comprises:
10-12 parts of angelica sinensis, 8-10 parts of peach kernel, 10-14 parts of morinda officinalis, 10-14 parts of codonopsis pilosula, 10-12 parts of fructus cannabis, 10-12 parts of trichosanthes kirilowii maxim, 10-14 parts of thunberg dwarf lilyturf tuber, 8-12 parts of almond, 10-14 parts of radix rehmanniae, 3-5 parts of safflower, 5-7 parts of cimicifugae foetidae, 8-12 parts of bighead atractylodes rhizome and 5-9 parts of fructus aurantii.
The second component comprises 2-4 parts of egg oil.
The parts are all calculated by weight.
The invention provides a prepared traditional Chinese medicine composition for clearing intestines and stomach and expelling toxin, which comprises the following steps:
mixing radix Angelicae sinensis, semen Persicae, radix Morindae officinalis, radix Codonopsis, fructus Cannabis, fructus Trichosanthis, radix Ophiopogonis, semen Armeniacae amarum, radix rehmanniae, Carthami flos, cimicifugae rhizoma, Atractylodis rhizoma, and fructus Aurantii, crushing;
the mixture after the crushing is put into a steamer for heating treatment, wherein the heating treatment in the embodiment is steaming; the steamed first mixture is placed, cooled and dried;
soaking the dried composition to obtain a filtrate;
mixing the filtrate with egg yolk oil, and extracting to obtain extractive solution.
In this embodiment, the cooking time is 10-15 min, and the extraction method of the filtrate comprises reduced pressure evaporation to dryness.
In the embodiment, the reduced pressure evaporation drying condition is that the negative pressure is 0.08pa, and the temperature is 55-60 ℃.
The following details are provided for the pharmacological actions of the Chinese herbs in the Chinese medicinal composition of the present invention:
safflower, peach kernel, Chinese angelica root: promoting blood circulation and removing blood stasis. Aims to improve local circulation and gradually improve the function of the large intestine of a patient with chronic constipation, thus being a permanent cure.
Fructus aurantii: promote gastrointestinal peristalsis and assist in relaxing bowels.
Zhe ophiopogon root and dried rehmannia root: nourish yin, moisten liquid and promote the production of body fluid.
Codonopsis pilosula and almond: moistening lung and tonifying qi, sufficient qi can push stool downward.
Morinda officinalis: to tonify kidney and moisten intestine.
Fructus cannabis: loosening the bowel to relieve constipation, blood deficiency and fluid deficiency, constipation due to intestinal dryness.
And (3) snakegourd fruit: clear heat and remove phlegm, relieve chest stuffiness and dissipate nodulation, moisten dryness and smooth intestines.
White atractylodes rhizome: tonify spleen and qi, dry dampness and induce diuresis.
Cimicifugae foetidae: has the functions of lifting hair, clearing heat and detoxicating.
Egg oil of chicken: due to excessive water absorption of the intestinal tract of a person with constipation, the toxin of the person is excessive, and the detoxification of egg oil is the safest and effective medicine.
The raw material medicaments are combined to clear intestines and stomach and expel toxin, and have extremely strong effects of reducing blood pressure and blood fat. In addition, the traditional Chinese medicine composition provided by the embodiment is suitable for all ages, is not classified into men and women, and has an obvious effect after being used.
The following are specific preparation examples of the traditional Chinese medicine composition provided in this example:
example 1
Mixing and smashing Chinese angelica 10 parts, peach kernel 8 parts, morinda officinalis 10 parts, codonopsis pilosula 10 parts, fructus cannabis 10 parts, trichosanthes kirilowii maxim 10 parts, thunberg dwarf lilyturf tuber 10 parts, almond 8 parts, dried rehmannia root 10 parts, safflower 3 parts, cimicifuga foetida 5 parts, bighead atractylodes rhizome 8 parts and bitter orange 5 parts, and putting into a steamer to steam for 10 minutes;
crushing 6 parts of hawthorn, putting into a steamer, steaming the composition in the steamer and cooling;
soaking the dried composition in ethanol for 4 hr, filtering to remove residue to obtain filtrate, mixing the filtrate with 2 parts of egg yolk oil, and evaporating under reduced pressure at 55 deg.C under 0.08pa to obtain pasty plant extract.
Example 2
The same method as in example 1 was adopted, except that 11 parts of angelica sinensis, 9 parts of peach kernel, 12 parts of morinda officinalis, 12 parts of codonopsis pilosula, 11 parts of fructus cannabis, 11 parts of trichosanthes kirilowii maxim, 12 parts of thunberg dwarf lilyturf tuber, 10 parts of almond, 12 parts of radix rehmanniae, 4 parts of safflower, 6 parts of cimicifugae foetidae, 10 parts of bighead atractylodes rhizome, 7 parts of fructus aurantii, and 3 parts of egg yolk oil.
The steaming time is 15min, and the temperature is 60 deg.C under reduced pressure.
Example 3
The same method as that of example 1 is adopted, except that 12 parts of angelica sinensis, 10 parts of peach kernel, 14 parts of morinda officinalis, 14 parts of codonopsis pilosula, 12 parts of fructus cannabis, 12 parts of trichosanthes kirilowii maxim, 14 parts of thunberg dwarf lilyturf tuber, 12 parts of almond, 14 parts of radix rehmanniae, 5 parts of safflower, 7 parts of cimicifugae foetidae, 12 parts of bighead atractylodes rhizome, 9 parts of fructus aurantii and 4 parts of egg yolk oil are adopted;
steaming for 13min at 57 deg.C under reduced pressure
Experimental example 1
Case 1, 100 patients with constipation were treated by the drug tracking of embodiment 1 of the present invention, wherein 37 men and 63 women aged 25-80 years old with a history of 1-40 years old, most patients had dry stools, and once every 3-5 days, had frequent dizziness, lassitude, anorexia, and many symptoms such as intestinal changes in the body, intestinal pore narrowing, balloon emptying, and pale complexion, hemorrhoids, anal fissure, rectocele, dysphoria, poor sleep, etc. were observed by hospital enteroscopy, while 42 patients had simple constipation, 39 men; constipation was accompanied by 58 cases of facial symptoms such as spots, acne, pimples, chloasma, etc., of which 52 women were present; most of the existing cathartics are taken to ensure that the excrement is smooth, the constipation still happens after the medicine is stopped, the state of illness is more serious in some cases, and the patient with a bigger age often suffers from profuse sweat stranguria and pain in defecation.
The treatment method comprises the following steps: the medicine is any one of powder, tablets, pills, capsules, granules, oral liquid and honeyed pills, is selected, 3 times a day, 6-10 g each time, 10 days is an external treatment course, 1-3 treatment courses are usually effective, persistent symptoms need 3-5 treatment courses, and various dosage forms can be used alternately. After 3 courses of administration, the clinical symptoms basically disappear, 71 patients with normal defecate after stopping administration are cured every day, and the significant rate is 71%. Clinical symptoms disappear partially, 22 people defecate for 2-3 days after stopping taking the medicine, the effective rate is 22%, and 7 invalid patients with symptoms still changed after 5 treatment courses have 7 ineffective rates. After 5 treatment courses, no toxic or side effect and no gastrointestinal discomfort are found. Along with the gradual normality of the stool, the face color of a patient begins to become ruddy, the symptoms such as spots, acne, pimples and chloasma on the face gradually decline, dizziness, tiredness, lassitude, limb tiredness, no speaking and the like are improved and gradually eliminated, the appetite is increased, and no relapse occurs in the follow-up visit for 2 years.
Case 2, the medicine of the invention is adopted to treat 100 cases of simple spots, acne, pimples, acne, chloasma and the like, wherein 33 cases of men and 67 cases of women are aged 18-50 years, and the patients are mainly young and strong.
Clinical symptoms: the face is dark, and has spots, acne, pimples, acne, chloasma and the like for a long time, and most of the existing medicines for treating the skin diseases are used, so the effect is not obvious or ineffective. The traditional Chinese medicine diagnosis considers that the disease is caused by the fact that external toxin and internal toxin enter viscera to form viscera internal stagnation and viscera disorder, and the treatment mainly aims at removing the viscera internal stagnation.
The treatment method comprises the following steps: the medicine is oral preparation, selected from one of powder, tablet, pill, capsule, granule, oral liquid and honeyed pill, 3 times per day, 6-10 g each time, 10 days as one external treatment course, usually 3-5 treatment courses are effective, the persistent ailment needs 6-9 treatment courses, and various dosage forms can be used alternatively.
The treatment effect is as follows: after 3-5 courses of administration, 37 cured patients with completely disappeared clinical symptoms are treated, the cure rate is 27%, 42 significant patients with basically disappeared clinical symptoms are treated, and the significant rate is 42%. 14 patients with partial reduction of clinical symptoms have an effective rate of 14 percent, and 7 patients with symptoms which can not be changed after 6 to 9 treatment courses have an ineffective rate of 7 percent. No obvious adverse drug reactions and toxic or side effects are seen in the treatment process, and no gastrointestinal discomfort is found after 9 treatment courses. No relapse is found in the follow-up 2 years.
The foregoing shows and describes the general principles, essential features, and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.
Claims (10)
1. A traditional Chinese medicine composition for clearing intestines and stomach and expelling toxin is characterized by comprising a first component and a second component, wherein the first component comprises:
10-12 parts of angelica sinensis, 8-10 parts of peach kernel, 10-14 parts of morinda officinalis, 10-14 parts of codonopsis pilosula, 10-12 parts of fructus cannabis, 10-12 parts of trichosanthes kirilowii maxim, 10-14 parts of thunberg dwarf lilyturf tuber, 8-12 parts of almond, 10-14 parts of radix rehmanniae, 3-5 parts of safflower, 5-7 parts of cimicifugae foetidae, 8-12 parts of bighead atractylodes rhizome and 5-9 parts of fructus aurantii.
2. The gastrointestinal tract cleansing and toxin expelling traditional Chinese medicine composition according to claim 1, wherein the second component comprises 2-4 parts of egg oil.
3. The traditional Chinese medicine composition for clearing intestines and stomach and expelling toxin according to claim 2, wherein the first component comprises 10-12 parts of angelica sinensis, 8-10 parts of peach kernel, 11-14 parts of morinda officinalis, 11-14 parts of codonopsis pilosula, 10-12 parts of fructus cannabis, 10-12 parts of trichosanthes kirilowii maxim, 11-14 parts of thunberg ophiopogon root, 9-12 parts of almond, 11-14 parts of radix rehmanniae, 3-5 parts of safflower, 5-7 parts of cimicifugae foetidae, 9-12 parts of bighead atractylodes rhizome and 6-9 parts of fructus aurantii; the second component comprises 2-4 parts of egg oil.
4. The traditional Chinese medicine composition for clearing intestines and stomach and expelling toxin according to claim 2, wherein the first component comprises 10-12 parts of angelica sinensis, 8-10 parts of peach kernel, 11-13 parts of morinda officinalis, 11-13 parts of codonopsis pilosula, 10-12 parts of fructus cannabis, 10-12 parts of trichosanthes kirilowii maxim, 11-13 parts of thunberg ophiopogon root, 9-11 parts of almond, 11-13 parts of radix rehmanniae, 3-5 parts of safflower, 5-7 parts of cimicifugae foetidae, 9-11 parts of bighead atractylodes rhizome and 6-8 parts of fructus aurantii; the second component comprises 5-7 parts of egg oil.
5. The traditional Chinese medicine composition for clearing intestine and stomach and expelling toxin according to claim 2, wherein the first component comprises 10 parts of angelica sinensis, 8 parts of peach kernel, 10 parts of morinda officinalis, 10 parts of codonopsis pilosula, 10 parts of fructus cannabis, 10 parts of trichosanthes kirilowii maxim, 10 parts of thunberg ophiopogon root, 8 parts of almond, 10 parts of radix rehmanniae, 3 parts of safflower, 5 parts of cimicifuga foetida, 8 parts of bighead atractylodes rhizome and 5 parts of fructus aurantii; the second component comprises 2 parts of egg yolk oil.
6. The traditional Chinese medicine composition for clearing intestines and stomach and expelling toxin according to claim 2, wherein the first component comprises 11 parts of angelica, 9 parts of peach kernel, 12 parts of morinda officinalis, 12 parts of codonopsis pilosula, 11 parts of fructus cannabis, 11 parts of trichosanthes kirilowii maxim, 12 parts of thunberg ophiopogon root, 10 parts of almond, 12 parts of radix rehmanniae, 4 parts of safflower, 6 parts of cimicifuga foetida, 10 parts of rhizoma atractylodis macrocephalae and 7 parts of fructus aurantii; the second component comprises 3 parts of egg oil.
7. The traditional Chinese medicine composition for clearing intestines and stomach and expelling toxin according to claim 2, wherein the first component comprises 12 parts of angelica sinensis, 10 parts of peach kernel, 14 parts of morinda officinalis, 14 parts of codonopsis pilosula, 12 parts of fructus cannabis, 12 parts of trichosanthes kirilowii maxim, 14 parts of thunberg ophiopogon root, 12 parts of almond, 14 parts of radix rehmanniae, 5 parts of safflower, 7 parts of cimicifuga foetida, 12 parts of bighead atractylodes rhizome and 9 parts of fructus aurantii; the second component comprises 4 parts of egg oil.
8. A preparation method of the traditional Chinese medicine composition for clearing intestines and stomach and expelling toxin according to any one of claims 1 to 7 is characterized by mixing and crushing the first component, heating, steaming the first mixture after heat treatment, fermenting to obtain the first composition, soaking the first composition to obtain a first filtrate, extracting the first filtrate, and adding the second component.
9. The preparation method of the traditional Chinese medicine composition for clearing intestines and stomach and expelling toxin according to claim 8, wherein the heating treatment comprises cooking, and the cooking time is 10-15 min; the extraction method of the first filtrate comprises reduced pressure evaporation to dryness.
10. The preparation method of the traditional Chinese medicine composition for clearing intestines and stomach and expelling toxin according to claim 9, wherein the reduced pressure evaporation drying condition is negative pressure of 0.08pa and temperature of 55-60 ℃.
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