CN111973490A - 一种液晶结构的护肤化妆品 - Google Patents
一种液晶结构的护肤化妆品 Download PDFInfo
- Publication number
- CN111973490A CN111973490A CN201910433572.1A CN201910433572A CN111973490A CN 111973490 A CN111973490 A CN 111973490A CN 201910433572 A CN201910433572 A CN 201910433572A CN 111973490 A CN111973490 A CN 111973490A
- Authority
- CN
- China
- Prior art keywords
- skin care
- parts
- care formulation
- skin
- formulation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000004973 liquid crystal related substance Substances 0.000 title abstract description 14
- 239000002537 cosmetic Substances 0.000 title abstract description 11
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 10
- 235000004433 Simmondsia californica Nutrition 0.000 claims abstract description 9
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 claims abstract description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 7
- 241000221095 Simmondsia Species 0.000 claims abstract description 5
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical class CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims abstract description 4
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims abstract description 4
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 claims abstract description 4
- 239000004475 Arginine Substances 0.000 claims abstract description 4
- 241000221096 Simmondsia chinensis Species 0.000 claims abstract description 4
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims abstract description 4
- 229920006037 cross link polymer Polymers 0.000 claims abstract description 4
- 229920006007 hydrogenated polyisobutylene Polymers 0.000 claims abstract description 4
- 235000015112 vegetable and seed oil Nutrition 0.000 claims abstract description 4
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims abstract description 3
- 150000002148 esters Chemical class 0.000 claims abstract description 3
- NOPFSRXAKWQILS-UHFFFAOYSA-N docosan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCCCCCO NOPFSRXAKWQILS-UHFFFAOYSA-N 0.000 claims description 6
- BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 claims description 6
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 claims description 6
- 235000019198 oils Nutrition 0.000 claims description 5
- 229920001184 polypeptide Polymers 0.000 claims description 4
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 4
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 4
- QGGBBQJHVCVVKM-XOBYPWAZSA-N (4s)-4-acetamido-5-[[(2s)-1-[[(2s)-1-[[(2s)-5-amino-1-[[(2s)-1-[[(2s)-1-[[(2s)-1-[[(2s)-1-amino-3-carboxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amin Chemical compound OC(=O)CC[C@H](NC(C)=O)C(=C)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(N)=O QGGBBQJHVCVVKM-XOBYPWAZSA-N 0.000 claims description 3
- JEBFVOLFMLUKLF-IFPLVEIFSA-N Astaxanthin Natural products CC(=C/C=C/C(=C/C=C/C1=C(C)C(=O)C(O)CC1(C)C)/C)C=CC=C(/C)C=CC=C(/C)C=CC2=C(C)C(=O)C(O)CC2(C)C JEBFVOLFMLUKLF-IFPLVEIFSA-N 0.000 claims description 3
- 229940078033 acetyl octapeptide-3 Drugs 0.000 claims description 3
- MQZIGYBFDRPAKN-ZWAPEEGVSA-N astaxanthin Chemical compound C([C@H](O)C(=O)C=1C)C(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)C(=O)[C@@H](O)CC1(C)C MQZIGYBFDRPAKN-ZWAPEEGVSA-N 0.000 claims description 3
- 229940022405 astaxanthin Drugs 0.000 claims description 3
- 235000013793 astaxanthin Nutrition 0.000 claims description 3
- 239000001168 astaxanthin Substances 0.000 claims description 3
- 229960000541 cetyl alcohol Drugs 0.000 claims description 3
- 229960000735 docosanol Drugs 0.000 claims description 3
- WQXNXVUDBPYKBA-YFKPBYRVSA-N ectoine Chemical compound CC1=[NH+][C@H](C([O-])=O)CCN1 WQXNXVUDBPYKBA-YFKPBYRVSA-N 0.000 claims description 3
- 239000003995 emulsifying agent Substances 0.000 claims description 3
- 235000011187 glycerol Nutrition 0.000 claims description 3
- 229940075529 glyceryl stearate Drugs 0.000 claims description 3
- GOQYKNQRPGWPLP-UHFFFAOYSA-N n-heptadecyl alcohol Natural products CCCCCCCCCCCCCCCCCO GOQYKNQRPGWPLP-UHFFFAOYSA-N 0.000 claims description 3
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 claims description 2
- AJLNZWYOJAWBCR-OOPVGHQCSA-N (4s)-4-acetamido-5-[[(2s)-1-[[(2s)-1-[[(2s)-5-amino-1-[[(2s)-1-[[(2s)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-car Chemical compound OC(=O)CC[C@H](NC(C)=O)C(=C)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCN=C(N)N)C(N)=O AJLNZWYOJAWBCR-OOPVGHQCSA-N 0.000 claims description 2
- 229940095094 acetyl hexapeptide-8 Drugs 0.000 claims description 2
- 108010006338 acetyl-glutamyl-glutamyl-methionyl-glutaminyl-arginyl-argininamide Proteins 0.000 claims description 2
- 229940012831 stearyl alcohol Drugs 0.000 claims description 2
- 239000000203 mixture Substances 0.000 claims 16
- 238000009472 formulation Methods 0.000 claims 15
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims 3
- TXFPEBPIARQUIG-UHFFFAOYSA-N 4'-hydroxyacetophenone Chemical compound CC(=O)C1=CC=C(O)C=C1 TXFPEBPIARQUIG-UHFFFAOYSA-N 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 235000013399 edible fruits Nutrition 0.000 claims 2
- 239000003974 emollient agent Substances 0.000 claims 2
- 239000000839 emulsion Substances 0.000 claims 2
- SHZIWNPUGXLXDT-UHFFFAOYSA-N ethyl hexanoate Chemical compound CCCCCC(=O)OCC SHZIWNPUGXLXDT-UHFFFAOYSA-N 0.000 claims 2
- RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 claims 2
- 239000004615 ingredient Substances 0.000 claims 2
- 230000003472 neutralizing effect Effects 0.000 claims 2
- -1 polyglycerol-3 Chemical compound 0.000 claims 2
- 239000003381 stabilizer Substances 0.000 claims 2
- 239000002562 thickening agent Substances 0.000 claims 2
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 claims 1
- CGPSWQBETUSORI-MTUNXJOQSA-N (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-(4-hydroxyphenyl)propanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-hydroxypropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-6-amino-N-[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]hexanamide Chemical compound C[C@@H](O)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(C)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O CGPSWQBETUSORI-MTUNXJOQSA-N 0.000 claims 1
- WSGCRSMLXFHGRM-DEVHWETNSA-N (2s)-2-[[(2s)-6-amino-2-[[(2s,3r)-2-[[(2s,3r)-2-[[(2s)-6-amino-2-(hexadecanoylamino)hexanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxybutanoyl]amino]hexanoyl]amino]-3-hydroxypropanoic acid Chemical compound CCCCCCCCCCCCCCCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(O)=O WSGCRSMLXFHGRM-DEVHWETNSA-N 0.000 claims 1
- 229940015975 1,2-hexanediol Drugs 0.000 claims 1
- PQUXFUBNSYCQAL-UHFFFAOYSA-N 1-(2,3-difluorophenyl)ethanone Chemical compound CC(=O)C1=CC=CC(F)=C1F PQUXFUBNSYCQAL-UHFFFAOYSA-N 0.000 claims 1
- JFSQSDAOQLNSQI-DTBJPNGVSA-N 2-[[(2s)-1-[(2s)-2-[[(2s)-2-[[2-[[(2s)-2-(hexadecanoylamino)-3-methylbutanoyl]amino]acetyl]amino]-3-methylbutanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]acetic acid Chemical compound CCCCCCCCCCCCCCCC(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(O)=O JFSQSDAOQLNSQI-DTBJPNGVSA-N 0.000 claims 1
- HIQIXEFWDLTDED-UHFFFAOYSA-N 4-hydroxy-1-piperidin-4-ylpyrrolidin-2-one Chemical compound O=C1CC(O)CN1C1CCNCC1 HIQIXEFWDLTDED-UHFFFAOYSA-N 0.000 claims 1
- ODHCTXKNWHHXJC-VKHMYHEASA-N 5-oxo-L-proline Chemical compound OC(=O)[C@@H]1CCC(=O)N1 ODHCTXKNWHHXJC-VKHMYHEASA-N 0.000 claims 1
- KWIUHFFTVRNATP-UHFFFAOYSA-N Betaine Natural products C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 claims 1
- YDSVPIYLRFZLAT-UHFFFAOYSA-N C(C)(=O)O.C(C)(=O)O.NC(CCC(=O)NCC1=CC=CC=C1)N Chemical compound C(C)(=O)O.C(C)(=O)O.NC(CCC(=O)NCC1=CC=CC=C1)N YDSVPIYLRFZLAT-UHFFFAOYSA-N 0.000 claims 1
- XMWRBQBLMFGWIX-UHFFFAOYSA-N C60 fullerene Chemical compound C12=C3C(C4=C56)=C7C8=C5C5=C9C%10=C6C6=C4C1=C1C4=C6C6=C%10C%10=C9C9=C%11C5=C8C5=C8C7=C3C3=C7C2=C1C1=C2C4=C6C4=C%10C6=C9C9=C%11C5=C5C8=C3C3=C7C1=C1C2=C4C6=C2C9=C5C3=C12 XMWRBQBLMFGWIX-UHFFFAOYSA-N 0.000 claims 1
- BYUQATUKPXLFLZ-UIOOFZCWSA-N CCCCCCCCCCCCCCCC(=O)NCC(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(O)=O)CC1=CN=CN1 Chemical compound CCCCCCCCCCCCCCCC(=O)NCC(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(O)=O)CC1=CN=CN1 BYUQATUKPXLFLZ-UIOOFZCWSA-N 0.000 claims 1
- QRYRORQUOLYVBU-VBKZILBWSA-N Carnosic acid Natural products CC([C@@H]1CC2)(C)CCC[C@]1(C(O)=O)C1=C2C=C(C(C)C)C(O)=C1O QRYRORQUOLYVBU-VBKZILBWSA-N 0.000 claims 1
- 108010087806 Carnosine Proteins 0.000 claims 1
- 108010016626 Dipeptides Proteins 0.000 claims 1
- 108010024636 Glutathione Proteins 0.000 claims 1
- MVORZMQFXBLMHM-QWRGUYRKSA-N Gly-His-Lys Chemical compound NCCCC[C@@H](C(O)=O)NC(=O)[C@@H](NC(=O)CN)CC1=CN=CN1 MVORZMQFXBLMHM-QWRGUYRKSA-N 0.000 claims 1
- 239000004354 Hydroxyethyl cellulose Substances 0.000 claims 1
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 claims 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 claims 1
- 239000004909 Moisturizer Substances 0.000 claims 1
- KWIUHFFTVRNATP-UHFFFAOYSA-O N,N,N-trimethylglycinium Chemical compound C[N+](C)(C)CC(O)=O KWIUHFFTVRNATP-UHFFFAOYSA-O 0.000 claims 1
- CQOVPNPJLQNMDC-UHFFFAOYSA-N N-beta-alanyl-L-histidine Natural products NCCC(=O)NC(C(O)=O)CC1=CN=CN1 CQOVPNPJLQNMDC-UHFFFAOYSA-N 0.000 claims 1
- 240000007817 Olea europaea Species 0.000 claims 1
- OQILCOQZDHPEAZ-UHFFFAOYSA-N Palmitinsaeure-octylester Natural products CCCCCCCCCCCCCCCC(=O)OCCCCCCCC OQILCOQZDHPEAZ-UHFFFAOYSA-N 0.000 claims 1
- 229920002385 Sodium hyaluronate Polymers 0.000 claims 1
- 229920002125 Sokalan® Polymers 0.000 claims 1
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 claims 1
- 241001135917 Vitellaria paradoxa Species 0.000 claims 1
- 235000018936 Vitellaria paradoxa Nutrition 0.000 claims 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 claims 1
- 229940048053 acrylate Drugs 0.000 claims 1
- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 claims 1
- 229960003237 betaine Drugs 0.000 claims 1
- CQOVPNPJLQNMDC-ZETCQYMHSA-N carnosine Chemical compound [NH3+]CCC(=O)N[C@H](C([O-])=O)CC1=CNC=N1 CQOVPNPJLQNMDC-ZETCQYMHSA-N 0.000 claims 1
- 229940044199 carnosine Drugs 0.000 claims 1
- 230000003750 conditioning effect Effects 0.000 claims 1
- 229920001577 copolymer Polymers 0.000 claims 1
- 229940008099 dimethicone Drugs 0.000 claims 1
- 239000004205 dimethyl polysiloxane Substances 0.000 claims 1
- 235000013870 dimethyl polysiloxane Nutrition 0.000 claims 1
- PKPOVTYZGGYDIJ-UHFFFAOYSA-N dioctyl carbonate Chemical compound CCCCCCCCOC(=O)OCCCCCCCC PKPOVTYZGGYDIJ-UHFFFAOYSA-N 0.000 claims 1
- GJQLBGWSDGMZKM-UHFFFAOYSA-N ethylhexyl palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC(CC)CCCCC GJQLBGWSDGMZKM-UHFFFAOYSA-N 0.000 claims 1
- 229910003472 fullerene Inorganic materials 0.000 claims 1
- 229960003180 glutathione Drugs 0.000 claims 1
- 125000003976 glyceryl group Chemical group [H]C([*])([H])C(O[H])([H])C(O[H])([H])[H] 0.000 claims 1
- FHKSXSQHXQEMOK-UHFFFAOYSA-N hexane-1,2-diol Chemical compound CCCCC(O)CO FHKSXSQHXQEMOK-UHFFFAOYSA-N 0.000 claims 1
- 239000003906 humectant Substances 0.000 claims 1
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 230000001333 moisturizer Effects 0.000 claims 1
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 claims 1
- 229940077272 palmitoyl hexapeptide-12 Drugs 0.000 claims 1
- 229940093441 palmitoyl oligopeptide Drugs 0.000 claims 1
- WXZMFSXDPGVJKK-UHFFFAOYSA-N pentaerythritol Chemical compound OCC(CO)(CO)CO WXZMFSXDPGVJKK-UHFFFAOYSA-N 0.000 claims 1
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims 1
- 229940079889 pyrrolidonecarboxylic acid Drugs 0.000 claims 1
- 229940047670 sodium acrylate Drugs 0.000 claims 1
- 229940010747 sodium hyaluronate Drugs 0.000 claims 1
- 229940080352 sodium stearoyl lactylate Drugs 0.000 claims 1
- ODFAPIRLUPAQCQ-UHFFFAOYSA-M sodium stearoyl lactylate Chemical compound [Na+].CCCCCCCCCCCCCCCCCC(=O)OC(C)C(=O)OC(C)C([O-])=O ODFAPIRLUPAQCQ-UHFFFAOYSA-M 0.000 claims 1
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims 1
- 229940074410 trehalose Drugs 0.000 claims 1
- LADGBHLMCUINGV-UHFFFAOYSA-N tricaprin Chemical compound CCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCC)COC(=O)CCCCCCCCC LADGBHLMCUINGV-UHFFFAOYSA-N 0.000 claims 1
- 239000000230 xanthan gum Substances 0.000 claims 1
- 229920001285 xanthan gum Polymers 0.000 claims 1
- 235000010493 xanthan gum Nutrition 0.000 claims 1
- 229940082509 xanthan gum Drugs 0.000 claims 1
- 230000003020 moisturizing effect Effects 0.000 abstract description 5
- DRRMRHKHTQRWMB-UHFFFAOYSA-N [3-(2-ethylhexanoyloxy)-2,2-bis(2-ethylhexanoyloxymethyl)propyl] 2-ethylhexanoate Chemical compound CCCCC(CC)C(=O)OCC(COC(=O)C(CC)CCCC)(COC(=O)C(CC)CCCC)COC(=O)C(CC)CCCC DRRMRHKHTQRWMB-UHFFFAOYSA-N 0.000 abstract description 3
- ACCCMOQWYVYDOT-UHFFFAOYSA-N hexane-1,1-diol Chemical compound CCCCCC(O)O ACCCMOQWYVYDOT-UHFFFAOYSA-N 0.000 abstract description 3
- PUGFCQQOYJMKOO-UHFFFAOYSA-N n-(3-hexadecoxy-2-hydroxypropyl)-n-(2-hydroxyethyl)hexadecanamide Chemical compound CCCCCCCCCCCCCCCCOCC(O)CN(CCO)C(=O)CCCCCCCCCCCCCCC PUGFCQQOYJMKOO-UHFFFAOYSA-N 0.000 abstract description 3
- 239000002994 raw material Substances 0.000 abstract description 3
- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 abstract description 2
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 abstract description 2
- 239000002085 irritant Substances 0.000 abstract 1
- 231100000021 irritant Toxicity 0.000 abstract 1
- 210000003491 skin Anatomy 0.000 description 31
- 238000003756 stirring Methods 0.000 description 7
- 229940106189 ceramide Drugs 0.000 description 6
- 210000000434 stratum corneum Anatomy 0.000 description 5
- 230000000694 effects Effects 0.000 description 4
- 230000001804 emulsifying effect Effects 0.000 description 4
- 238000010438 heat treatment Methods 0.000 description 4
- 150000002632 lipids Chemical class 0.000 description 4
- YDNKGFDKKRUKPY-JHOUSYSJSA-N C16 ceramide Natural products CCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@H](O)C=CCCCCCCCCCCCCC YDNKGFDKKRUKPY-JHOUSYSJSA-N 0.000 description 3
- CRJGESKKUOMBCT-VQTJNVASSA-N N-acetylsphinganine Chemical compound CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC(C)=O CRJGESKKUOMBCT-VQTJNVASSA-N 0.000 description 3
- 230000032683 aging Effects 0.000 description 3
- ZVEQCJWYRWKARO-UHFFFAOYSA-N ceramide Natural products CCCCCCCCCCCCCCC(O)C(=O)NC(CO)C(O)C=CCCC=C(C)CCCCCCCCC ZVEQCJWYRWKARO-UHFFFAOYSA-N 0.000 description 3
- 150000001783 ceramides Chemical class 0.000 description 3
- 238000001816 cooling Methods 0.000 description 3
- 238000002156 mixing Methods 0.000 description 3
- VVGIYYKRAMHVLU-UHFFFAOYSA-N newbouldiamide Natural products CCCCCCCCCCCCCCCCCCCC(O)C(O)C(O)C(CO)NC(=O)CCCCCCCCCCCCCCCCC VVGIYYKRAMHVLU-UHFFFAOYSA-N 0.000 description 3
- RJZNPROJTJSYLC-LLINQDLYSA-N (4s)-4-acetamido-5-[[(2s)-1-[[(2s)-1-[[(2s)-5-amino-1-[[(2s)-1-[[(2s)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-car Chemical compound OC(=O)CC[C@H](NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O RJZNPROJTJSYLC-LLINQDLYSA-N 0.000 description 2
- 206010012438 Dermatitis atopic Diseases 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 201000008937 atopic dermatitis Diseases 0.000 description 2
- 230000004888 barrier function Effects 0.000 description 2
- 239000011449 brick Substances 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 238000004945 emulsification Methods 0.000 description 2
- 210000002615 epidermis Anatomy 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000008439 repair process Effects 0.000 description 2
- 230000008591 skin barrier function Effects 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 230000002087 whitening effect Effects 0.000 description 2
- 206010001488 Aggression Diseases 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- 102000016942 Elastin Human genes 0.000 description 1
- 108010014258 Elastin Proteins 0.000 description 1
- 239000004976 Lyotropic liquid crystal Substances 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000016571 aggressive behavior Effects 0.000 description 1
- 230000000172 allergic effect Effects 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 229940099417 ceramide 2 Drugs 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 229920002549 elastin Polymers 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 238000005562 fading Methods 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 235000021588 free fatty acids Nutrition 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 210000002510 keratinocyte Anatomy 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 239000005445 natural material Substances 0.000 description 1
- 231100000344 non-irritating Toxicity 0.000 description 1
- 230000000474 nursing effect Effects 0.000 description 1
- 206010033675 panniculitis Diseases 0.000 description 1
- 229940068065 phytosterols Drugs 0.000 description 1
- 230000037307 sensitive skin Effects 0.000 description 1
- 230000009759 skin aging Effects 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 210000004304 subcutaneous tissue Anatomy 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0295—Liquid crystals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/342—Alcohols having more than seven atoms in an unbroken chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
- A61K8/553—Phospholipids, e.g. lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8105—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers
- A61K8/8111—Homopolymers or copolymers of aliphatic olefines, e.g. polyethylene, polyisobutene; Compositions of derivatives of such polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Cosmetics (AREA)
Abstract
本发明涉及一种护肤化妆品，其特点是具有层状液晶的微观结构。其中原料的重量组分为：丁二醇2～5份、甘油2～5份、丙烯酸(酯)类/C10‑30烷醇丙烯酸酯交联聚合物0.1～0.5份、精氨酸0.1～0.5份、鲸蜡基‑PG羟乙基棕榈酰胺0.1～0.5份、植物甾醇类0.01～0.5份、氢化卵磷脂0.1～2.0份、甘油硬脂酸酯0.1～0.5份、氢化聚异丁烯1～3份、霍霍巴(SIMMONDSIA CHINENSIS)籽油1～3份、季戊四醇四(乙基己酸)酯1～3份、乙酰基八肽‑31～3份、水60～80份、己二醇1～3份。实现了具有层状液晶结构护肤的工业化大生产。层状的结构赋予产品润滑的肤感。产品温和不刺激，对皮肤具有极好的保湿和修复功能。
Description
技术领域
本发明涉及一种护肤用化妆品，确切为具有液晶结构的功效型护肤品，属于日化产品技术领域。
背景技术
进入全球化和信息化的新时代，全球化妆品纷纷涌进中国市场，化妆品行业也经历了快速的发展。原材料，配方设计和功效评价等方面技术水平显著提高。产品功能越来越细分化与多功效，从简单的保湿到抗老化，美白淡斑和多功效合一。
随着经济的发展，环境污染问题日趋凸显，人们的生活节奏加快，饮食不规律都对人们的皮肤产生不可逆转的影响。使用化妆品的消费者年龄层次越来越广泛，使用频率显著增加。
目前市场上不乏各种保湿，敏感肌肤修复，美白以及抗衰老产品。但是仍缺乏安全有效的温和护肤产品。
皮肤的结构从外到内依次为表皮层，真皮层以及皮下组织。其中表皮层的最外层即角质层与护肤产品之间接触，关系最为密切。研究角质层结构的经典模型(砖墙模型)，主要观点为角质层由角质细胞与细胞间脂质按照类似砖墙的结构排列，防止皮肤水分散失，同时保护肌肤免于外界的侵害。
研究发现，细胞间脂质的组成成分为神经酰胺，胆固醇，游离脂肪酸以及天然保湿因子(NMF)。这些成分形成溶致液晶的结构。选择皮肤中天然存在的物质成分，形成与皮肤角质层结构类似的护肤产品，对皮肤安全温和，同时具有增强的护肤功效。
发明内容
本发明在于通过选择类神经酰胺，植物甾醇类，配合乳化剂甘油硬脂酸酯，制成一种具有层状液晶结构的护肤产品。其安全温和，通过负载不同的功效成分，达到改善皮肤状况的效果。
本发明的技术方案如下：
一种具有液晶结构的护肤化妆品，包括以下重量份的组分：丁二醇2-5份、甘油2-5份、丙烯酸(酯)类/C10-30烷醇丙烯酸酯交联聚合物0.1-0.5份、精氨酸0.1-0.5份、鲸蜡基-PG羟乙基棕榈酰胺0.1-0.5份、植物甾醇类0.01-0.5份、氢化卵磷脂0.1-2.0份、甘油硬脂酸酯0.1-0.5份、氢化聚异丁烯1-3份、霍霍巴(SIMMONDSIA CHINENSIS)籽油1-3份、季戊四醇四(乙基己酸)酯1-3份、乙酰基八肽-31-3份、水60-80份、己二醇1-3份。
上述原料中还可加入鲸蜡醇1-3份、硬脂醇1-3份、山嵛醇1-3份、依克多因0.1-1份、虾青素0.01-1份、乙酰基六肽1-2份。
其中：
A组分为：水、丁二醇、甘油、丙烯酸(酯)类/C10-30烷醇丙烯酸酯交联聚合物、精氨酸；
B组分为：鲸蜡基-PG羟乙基棕榈酰胺、植物甾醇类、氢化卵磷脂、甘油硬脂酸酯、氢化聚异丁烯、霍霍巴(SIMMONDSIA CHINENSIS)籽油、季戊四醇四(乙基己酸)酯、鲸蜡醇、硬脂醇、山嵛醇；
C组分为：依克多因、乙酰基八肽-3、虾青素、乙酰基六肽、己二醇。
制备上述液晶结构的护肤化妆品的方法：将A组组分加入水锅中，并加热至70-75℃，搅拌均匀；将B组组分加入油锅中，加热至70-75℃，搅拌均匀；将A组组分和B组组分在乳化锅中混合，均质乳化约10分钟；乳化完成后，边搅拌边降温至50℃，加入C组组分；搅拌30分钟后出料，测试PH值和微生物；制备的膏体外观均匀细腻。
所使用的类神经酰胺具有与神经酰胺神2相似的化学结构。神经酰胺是众所周知的角质层脂质，在皮肤屏障功能维护方面起着重要的作用。随着神经酰胺和其它角质层细胞间脂质量的减少，对抗特应性皮炎的屏障功能降低。特应性皮炎患者的神经酰胺代谢异常导致神经酰胺水平降低。据报道，使用含类神经酰胺的屏障修复霜，经表皮水分损失测定显示，能改善过敏性症状以及皮肤屏障功能。
所使用的护肤多肽是皮肤中胶原蛋白和弹性蛋白的片段，通常含有3～8个氨基酸，如乙酰基六肽-8和乙酰基八肽-3。衰老的迹象通常反应在人体的皮肤上，干燥、敏感和细小的皱纹。通过不同种类多肽的组合，能改善可见的肌肤老化包括细纹，皮肤粗糙、干燥；改善眼部皮肤的老化症状包括眼袋和黑眼圈。
本发明制备的护肤化妆品具有以下特点：
制备的护肤化妆品具有稳定的液晶结构，在1mol/L的氯化钠条件下仍能保持液晶结构。
具体实施方式
本发明的实施例为：
一种液晶结构的护肤品配方如表1
(单位为重量份)
表1一种液晶结构的护肤品的配方
具有液晶结构的护肤品的调配方法为：将A组组分加入水锅中，并加热至70-75℃，搅拌均匀；将B组组分加入油锅中，加热至70-75℃，搅拌均匀；将A组组分和B组组分在乳化锅中混合，均质乳化约10分钟；乳化完成后，边搅拌边降温至50℃，加入C组组分；冷却至室温进行灌装即可。
所得产品为外观光亮，粘稠的乳霜状护肤品，安全、温和不刺激。具有层状液晶结构。对肌肤具有优异的保湿护理功效。
上述实例为本发明较佳的实施方式，单本发明的实施方式不受上述实施实例的限制。
Claims (13)
1.一种具有液晶结构的护肤品配方，其特征为含有约0.1％至约2.0％(％w/w)的类神经酰胺和约0.05％-2.0％的植物甾醇类。
2.如权利要求1中的护肤品配方，其特征在于含有约10.0％至约20.0％(％w/w)的保湿剂。
3.如权利要求1中的护肤品配方，其特征在于含有约2.0％至约40.0％(％w/w)的油脂润肤剂。
4.如权利要求1中的护肤品配方，其特征在于含有约0.1％至约10.0％(％w/w)的护肤多肽。
5.如权利要求1中的护肤品配方，配方中的外加成分适用于角质组织，具有调理皮肤的作用。
6.如权利要求1中的护肤品配方，其特征在于含有约0.2％至约2.0％(％w/w)的增稠剂和约0.2％至约2.0％(％w/w)的中和剂。
7.如权利要求1中的护肤品配方，其特征在于含有约0.2％至约2.0％(％w/w)的乳化剂和约0.2％至约10.0％(％w/w)的乳化稳定剂。
8.如权利要求2中的护肤品配方，配方中含有至少一种或几种保湿剂为甘油、丁二醇、海藻糖、甜菜碱、透明质酸钠、聚甘油-3、吡咯烷酮羧酸、甘油聚醚-26。
9.如权利要求3中的护肤品配方，配方中含有至少一种或几种油脂润肤剂为辛酸/癸酸甘油三酯、氢化聚异丁烯、油橄榄(OLEAEUROPAEA)果油、肉豆蔻酸异丙酯、棕榈酸乙基己酯、碳酸二辛酯、霍霍巴(SIMMONDSIA CHINENSIS)籽油、牛油果树(BUTYROSPERMUM PARKII)果脂、聚二甲基硅氧烷、聚二甲基硅氧烷醇、季戊四醇四(乙基己酸)酯、霍霍巴酯类。
10.如权利要求4中的护肤品配方，配方中含有至少一种或几种护肤多肽为乙酰基六肽-8、乙酰基八肽-3、二肽二氨基丁酰苄基酰胺二乙酸盐、棕榈酰五肽-4、棕榈酰三肽-1、肌肽、己酰基四肽-3、乙酰基十肽-3、乙酰基六肽-30、棕榈酰六肽-12、铜肽、谷胱甘肽。
11.如权利要求5中的护肤品配方，配方中的至少一种外加成分为依克多因、虾青素、温泉水、富勒烯、对羟基苯乙酮、1，2-己二醇。
12.如权利要求6中的护肤品配方，配方中含有至少一种或几种增稠剂为卡波姆、黄原胶、羟乙基纤维素、丙烯酸(酯)类/C10-30烷醇丙烯酸酯交联聚合物、丙烯酸钠/丙烯酰二甲基牛磺酸钠共聚物；配方中含有至少一种或几种中和剂为精氨酸和氢氧化钠。
13.如权利要求7中的护肤品配方，配方中含有至少一种或几种乳化剂为氢化卵磷脂、甘油硬脂酸酯、硬脂酰乳酰乳酸钠；配方中含有至少一种或几种乳化稳定剂为鲸蜡醇、硬脂醇、山嵛醇。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910433572.1A CN111973490A (zh) | 2019-05-23 | 2019-05-23 | 一种液晶结构的护肤化妆品 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910433572.1A CN111973490A (zh) | 2019-05-23 | 2019-05-23 | 一种液晶结构的护肤化妆品 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN111973490A true CN111973490A (zh) | 2020-11-24 |
Family
ID=73436499
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910433572.1A Pending CN111973490A (zh) | 2019-05-23 | 2019-05-23 | 一种液晶结构的护肤化妆品 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN111973490A (zh) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112826762A (zh) * | 2021-01-07 | 2021-05-25 | 广州艾蓓生物科技有限公司 | 一种双连续型微乳液组合物及其应用 |
| CN113693996A (zh) * | 2021-08-20 | 2021-11-26 | 上海溪上生物科技有限公司 | 一种含有大米酒糟发酵产物和棕榈酰五肽的抗衰老组合物 |
| CN115778835A (zh) * | 2022-12-29 | 2023-03-14 | 羽楠(广州)化妆品有限公司 | 一种聚甘油酯润肤霜及其制备方法 |
| CN116327630A (zh) * | 2023-05-19 | 2023-06-27 | 华东理工大学 | 一种大鲵肽复合液晶乳液制备及应用 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20080090741A (ko) * | 2007-04-06 | 2008-10-09 | 주식회사 코리아나화장품 | 아미노 레불리닉산을 배합시킨 액정 유화 베이스를포함하는 피부보호용 화장료 조성물 |
| CN104814881A (zh) * | 2015-05-07 | 2015-08-05 | 广州市花安堂生物科技有限公司 | 一种保湿修复组合物及由其构筑的表皮仿生膜液晶复合体 |
| CN107049903A (zh) * | 2017-05-16 | 2017-08-18 | 曼秀雷敦(中国)药业有限公司 | 一种用于敏感肌肤的膏霜及其制备方法 |
| CN107213027A (zh) * | 2017-06-30 | 2017-09-29 | 广州澳希亚实业有限公司 | 一种具有修复润肤功能的化妆品组合物及其制备方法 |
-
2019
- 2019-05-23 CN CN201910433572.1A patent/CN111973490A/zh active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20080090741A (ko) * | 2007-04-06 | 2008-10-09 | 주식회사 코리아나화장품 | 아미노 레불리닉산을 배합시킨 액정 유화 베이스를포함하는 피부보호용 화장료 조성물 |
| CN104814881A (zh) * | 2015-05-07 | 2015-08-05 | 广州市花安堂生物科技有限公司 | 一种保湿修复组合物及由其构筑的表皮仿生膜液晶复合体 |
| CN107049903A (zh) * | 2017-05-16 | 2017-08-18 | 曼秀雷敦(中国)药业有限公司 | 一种用于敏感肌肤的膏霜及其制备方法 |
| CN107213027A (zh) * | 2017-06-30 | 2017-09-29 | 广州澳希亚实业有限公司 | 一种具有修复润肤功能的化妆品组合物及其制备方法 |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112826762A (zh) * | 2021-01-07 | 2021-05-25 | 广州艾蓓生物科技有限公司 | 一种双连续型微乳液组合物及其应用 |
| CN112826762B (zh) * | 2021-01-07 | 2022-09-27 | 广州艾蓓生物科技有限公司 | 一种双连续型微乳液组合物及其应用 |
| CN113693996A (zh) * | 2021-08-20 | 2021-11-26 | 上海溪上生物科技有限公司 | 一种含有大米酒糟发酵产物和棕榈酰五肽的抗衰老组合物 |
| CN115778835A (zh) * | 2022-12-29 | 2023-03-14 | 羽楠(广州)化妆品有限公司 | 一种聚甘油酯润肤霜及其制备方法 |
| CN116327630A (zh) * | 2023-05-19 | 2023-06-27 | 华东理工大学 | 一种大鲵肽复合液晶乳液制备及应用 |
| CN116327630B (zh) * | 2023-05-19 | 2024-05-24 | 华东理工大学 | 一种大鲵肽复合液晶乳液制备及应用 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN111249209B (zh) | 一种保湿修护霜及其制备方法 | |
| CN111973490A (zh) | 一种液晶结构的护肤化妆品 | |
| US9855199B2 (en) | Cosmetic base composition and its use | |
| US8268335B2 (en) | Skin treatment systems | |
| CN110664644B (zh) | 一种含叶酸的护肤组合物、精华及其制备方法 | |
| CN111840161A (zh) | 一种抗衰提亮组合物及其应用和制备方法 | |
| WO2008154483A2 (en) | New and improved skin treatment systems | |
| CN110974767A (zh) | 用于皮肤屏障再生修复的组合物及其应用 | |
| CN109549863A (zh) | 一种美白组合物及其制备方法 | |
| CN109908021A (zh) | 一种具有修复作用的含水唇膏产品及其制备方法 | |
| JP2020128382A (ja) | ビタミンｄ様作用剤 | |
| JP2013527190A (ja) | 角化膜の成熟欠陥を通して生じる疾患又は症状の処置に有用な局所用薬学的又は化粧品組成物 | |
| CN115154375A (zh) | 一种稳定且具有修护及舒缓功效的清洁组合物 | |
| JP2016515567A (ja) | ポリゴヌム・ビストルタ抽出物の美容又は皮膚科学的な使用 | |
| CN116583264A (zh) | 包含蔗糖酯和溶剂的化妆品组合物 | |
| CN108653176A (zh) | 一种抗皱修复组合物及其在化妆品中的应用 | |
| KR20030085903A (ko) | 천연세라마이드, 파이토스핑고신, 콜레스테롤 및 레시틴을함유하는 피부보호용 조성물 및 그의 제조방법 | |
| CN108653088B (zh) | 一种水漾丝滑润泽霜 | |
| AU2018204216B2 (en) | Skin mimicking emulsion | |
| CN113749972B (zh) | 一种具有抗皱效果的组合物及其在化妆品中的应用 | |
| US9974734B2 (en) | Cosmetic composition for moisturizing keratinic tissue | |
| JP6207184B2 (ja) | 化粧料及び皮膚外用剤 | |
| CN115778875A (zh) | 一种抗衰老护肤组合物及其制备方法 | |
| WO2022223000A1 (zh) | 保湿组合物、皮肤修护特护霜、粉底组合物及其制备方法 | |
| US9040097B2 (en) | Compositions for improving skin appearance |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| DD01 | Delivery of document by public notice | ||
| DD01 | Delivery of document by public notice |
Addressee: Patents of Metre Biotechnology (Shanghai) Co.,Ltd. The person in charge Document name: Notice of Approval of Claim for Restoration of Rights Addressee: Patents of Metre Biotechnology (Shanghai) Co.,Ltd. The person in charge Document name: Notice on the Application for Invention Patent Entering the Substantive Examination Stage |
|
| DD01 | Delivery of document by public notice | ||
| DD01 | Delivery of document by public notice |
Addressee: Metri Biotechnology (Shanghai) Co.,Ltd. Person in charge of patents Document name: Notice of First Examination Opinion |