CN111971562A - 法伯病标志物及其用途 - Google Patents

法伯病标志物及其用途 Download PDF

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Publication number
CN111971562A
CN111971562A CN201980008575.9A CN201980008575A CN111971562A CN 111971562 A CN111971562 A CN 111971562A CN 201980008575 A CN201980008575 A CN 201980008575A CN 111971562 A CN111971562 A CN 111971562A
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CN
China
Prior art keywords
cd11b
mhcii
subject
cells
mid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201980008575.9A
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English (en)
Chinese (zh)
Inventor
C·科克里
B·桑佩
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Arthur Reagan
Original Assignee
Real Vanguard
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Real Vanguard filed Critical Real Vanguard
Priority to CN202311688835.6A priority Critical patent/CN118112249A/zh
Publication of CN111971562A publication Critical patent/CN111971562A/zh
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/50—Hydrolases (3) acting on carbon-nitrogen bonds, other than peptide bonds (3.5), e.g. asparaginase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/01—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1)
    • C12Y305/01023—Ceramidase (3.5.1.23)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN201980008575.9A 2018-03-27 2019-03-22 法伯病标志物及其用途 Pending CN111971562A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202311688835.6A CN118112249A (zh) 2018-03-27 2019-03-22 法伯病标志物及其用途

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862648775P 2018-03-27 2018-03-27
US62/648,775 2018-03-27
PCT/IB2019/000290 WO2019186272A1 (en) 2018-03-27 2019-03-22 Farber disease markers and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN202311688835.6A Division CN118112249A (zh) 2018-03-27 2019-03-22 法伯病标志物及其用途

Publications (1)

Publication Number Publication Date
CN111971562A true CN111971562A (zh) 2020-11-20

Family

ID=66530353

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201980008575.9A Pending CN111971562A (zh) 2018-03-27 2019-03-22 法伯病标志物及其用途
CN202311688835.6A Pending CN118112249A (zh) 2018-03-27 2019-03-22 法伯病标志物及其用途

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN202311688835.6A Pending CN118112249A (zh) 2018-03-27 2019-03-22 法伯病标志物及其用途

Country Status (15)

Country Link
EP (1) EP3775924A1 (https=)
JP (2) JP2021516757A (https=)
KR (2) KR20200136367A (https=)
CN (2) CN111971562A (https=)
AU (1) AU2019244477A1 (https=)
BR (1) BR112020016435A2 (https=)
CA (1) CA3090354A1 (https=)
CL (1) CL2020002105A1 (https=)
CO (1) CO2020010043A2 (https=)
IL (2) IL311212A (https=)
MX (1) MX2020008377A (https=)
PH (1) PH12020551206A1 (https=)
RU (1) RU2020119065A (https=)
SG (1) SG11202007508TA (https=)
WO (1) WO2019186272A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020152532A1 (en) * 2019-01-23 2020-07-30 Enzyvant Therapeutics Gmbh Method of ameliorating a pro-inflammatory immunophenotype in farber disease subjects by repeated administration of a recombinant human acid ceramidase
US20240180982A1 (en) * 2021-03-29 2024-06-06 University College Cardiff Consultants Limited Modified adenovirus

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5059421A (en) 1985-07-26 1991-10-22 The Liposome Company, Inc. Preparation of targeted liposome systems of a defined size distribution
US5631237A (en) 1992-12-22 1997-05-20 Dzau; Victor J. Method for producing in vivo delivery of therapeutic agents via liposomes
WO1995001164A1 (en) 1993-06-30 1995-01-12 Genentech, Inc. Method for preparing liposomes
US5885613A (en) 1994-09-30 1999-03-23 The University Of British Columbia Bilayer stabilizing components and their use in forming programmable fusogenic liposomes
US5643599A (en) 1995-06-07 1997-07-01 President And Fellows Of Harvard College Intracellular delivery of macromolecules
CA2905449C (en) 2013-03-14 2024-09-10 Icahn School Of Medicine At Mount Sinai THERAPEUTIC COMPOSITIONS OF ACID CERAMIDASE AND THEIR PROCESSES OF MANUFACTURE AND USE
EP3115786A1 (en) * 2015-07-08 2017-01-11 Centogene AG Method for the diagnosis of farber's disease

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
B S HANNA等: "Depletion of CLL-associated patrolling monocytes and macrophages controls disease development and repairs immune dysfunction in vivo", ，,", LEUKEMIA, pages 570 - 579 *

Also Published As

Publication number Publication date
RU2020119065A (ru) 2022-04-27
JP2021516757A (ja) 2021-07-08
WO2019186272A1 (en) 2019-10-03
EP3775924A1 (en) 2021-02-17
AU2019244477A1 (en) 2020-06-25
CN118112249A (zh) 2024-05-31
IL276420A (en) 2020-09-30
JP2023159164A (ja) 2023-10-31
CA3090354A1 (en) 2019-10-03
MX2020008377A (es) 2020-09-25
PH12020551206A1 (en) 2021-04-19
BR112020016435A2 (pt) 2020-12-15
SG11202007508TA (en) 2020-09-29
CL2020002105A1 (es) 2020-12-04
IL311212A (en) 2024-05-01
KR20200136367A (ko) 2020-12-07
CO2020010043A2 (es) 2020-11-10
KR20240111011A (ko) 2024-07-16

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PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
TA01 Transfer of patent application right
TA01 Transfer of patent application right

Effective date of registration: 20211203

Address after: Delaware

Applicant after: Arthur Reagan

Address before: Basel, Switzerland

Applicant before: Real Vanguard

WD01 Invention patent application deemed withdrawn after publication
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20201120