CN111840405A - Sleep-aiding foot patch and preparation method thereof - Google Patents
Sleep-aiding foot patch and preparation method thereof Download PDFInfo
- Publication number
- CN111840405A CN111840405A CN202010629245.6A CN202010629245A CN111840405A CN 111840405 A CN111840405 A CN 111840405A CN 202010629245 A CN202010629245 A CN 202010629245A CN 111840405 A CN111840405 A CN 111840405A
- Authority
- CN
- China
- Prior art keywords
- parts
- powder
- sleep
- aiding
- oyster
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000002360 preparation method Methods 0.000 title description 10
- 239000000843 powder Substances 0.000 claims abstract description 147
- 239000003814 drug Substances 0.000 claims abstract description 66
- 241000237502 Ostreidae Species 0.000 claims abstract description 34
- 235000020636 oyster Nutrition 0.000 claims abstract description 34
- 235000017166 Bambusa arundinacea Nutrition 0.000 claims abstract description 30
- 235000017491 Bambusa tulda Nutrition 0.000 claims abstract description 30
- 235000015334 Phyllostachys viridis Nutrition 0.000 claims abstract description 30
- 239000011425 bamboo Substances 0.000 claims abstract description 30
- 239000000052 vinegar Substances 0.000 claims abstract description 29
- 235000021419 vinegar Nutrition 0.000 claims abstract description 29
- SZVJSHCCFOBDDC-UHFFFAOYSA-N iron(II,III) oxide Inorganic materials O=[Fe]O[Fe]O[Fe]=O SZVJSHCCFOBDDC-UHFFFAOYSA-N 0.000 claims abstract description 27
- 239000000341 volatile oil Substances 0.000 claims abstract description 24
- 244000178870 Lavandula angustifolia Species 0.000 claims abstract description 22
- 235000010663 Lavandula angustifolia Nutrition 0.000 claims abstract description 22
- 239000000919 ceramic Substances 0.000 claims abstract description 22
- 239000001102 lavandula vera Substances 0.000 claims abstract description 22
- 235000018219 lavender Nutrition 0.000 claims abstract description 22
- 239000002994 raw material Substances 0.000 claims abstract description 20
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims abstract description 14
- 235000003140 Panax quinquefolius Nutrition 0.000 claims abstract description 14
- 235000008434 ginseng Nutrition 0.000 claims abstract description 14
- 244000018716 Impatiens biflora Species 0.000 claims abstract description 10
- 235000015912 Impatiens biflora Nutrition 0.000 claims abstract description 10
- 244000236658 Paeonia lactiflora Species 0.000 claims abstract description 10
- 235000008598 Paeonia lactiflora Nutrition 0.000 claims abstract description 10
- 235000005155 Tanacetum balsamita Nutrition 0.000 claims abstract description 10
- 240000000559 Albizia odoratissima Species 0.000 claims abstract description 9
- 235000011438 Albizia odoratissima Nutrition 0.000 claims abstract description 9
- 241001080798 Polygala tenuifolia Species 0.000 claims abstract description 9
- 240000006079 Schisandra chinensis Species 0.000 claims abstract description 9
- 235000008422 Schisandra chinensis Nutrition 0.000 claims abstract description 9
- 244000082204 Phyllostachys viridis Species 0.000 claims abstract 5
- 239000000203 mixture Substances 0.000 claims description 13
- 239000000463 material Substances 0.000 claims description 12
- 238000000034 method Methods 0.000 claims description 12
- 239000007788 liquid Substances 0.000 claims description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 10
- 229940079593 drug Drugs 0.000 claims description 9
- 238000000605 extraction Methods 0.000 claims description 9
- 238000001035 drying Methods 0.000 claims description 7
- 239000008367 deionised water Substances 0.000 claims description 5
- 229910021641 deionized water Inorganic materials 0.000 claims description 5
- 238000004519 manufacturing process Methods 0.000 claims description 5
- 238000002156 mixing Methods 0.000 claims description 5
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims description 5
- 239000004745 nonwoven fabric Substances 0.000 claims description 5
- 238000007873 sieving Methods 0.000 claims description 4
- 238000005303 weighing Methods 0.000 claims description 4
- 241000628997 Flos Species 0.000 claims description 3
- 238000001816 cooling Methods 0.000 claims description 3
- 238000001914 filtration Methods 0.000 claims description 3
- 238000010438 heat treatment Methods 0.000 claims description 3
- 238000010298 pulverizing process Methods 0.000 claims description 3
- 238000003756 stirring Methods 0.000 claims description 3
- 239000002245 particle Substances 0.000 claims description 2
- 210000000582 semen Anatomy 0.000 claims description 2
- 241000208340 Araliaceae Species 0.000 claims 4
- 230000000694 effects Effects 0.000 abstract description 19
- 210000004185 liver Anatomy 0.000 abstract description 19
- 230000017531 blood circulation Effects 0.000 abstract description 7
- 210000003734 kidney Anatomy 0.000 abstract description 7
- 210000005036 nerve Anatomy 0.000 abstract description 7
- 230000003860 sleep quality Effects 0.000 abstract description 7
- 230000003213 activating effect Effects 0.000 abstract description 5
- 230000002040 relaxant effect Effects 0.000 abstract description 4
- 210000002435 tendon Anatomy 0.000 abstract description 4
- 230000004060 metabolic process Effects 0.000 abstract description 3
- 210000003205 muscle Anatomy 0.000 abstract description 2
- 244000131316 Panax pseudoginseng Species 0.000 abstract 1
- 210000002683 foot Anatomy 0.000 description 43
- 241001330002 Bambuseae Species 0.000 description 25
- 210000002216 heart Anatomy 0.000 description 19
- 239000008280 blood Substances 0.000 description 15
- 210000004369 blood Anatomy 0.000 description 14
- 239000000047 product Substances 0.000 description 11
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 9
- 240000004371 Panax ginseng Species 0.000 description 9
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 8
- 206010022437 insomnia Diseases 0.000 description 8
- 230000002936 tranquilizing effect Effects 0.000 description 8
- 230000000052 comparative effect Effects 0.000 description 7
- 238000009472 formulation Methods 0.000 description 7
- 206010062717 Increased upper airway secretion Diseases 0.000 description 6
- 239000004480 active ingredient Substances 0.000 description 6
- 208000026435 phlegm Diseases 0.000 description 6
- 238000010521 absorption reaction Methods 0.000 description 5
- 230000001914 calming effect Effects 0.000 description 5
- 230000007812 deficiency Effects 0.000 description 5
- 230000001976 improved effect Effects 0.000 description 5
- 230000008569 process Effects 0.000 description 5
- 239000000126 substance Substances 0.000 description 5
- 239000005913 Maltodextrin Substances 0.000 description 4
- 229920002774 Maltodextrin Polymers 0.000 description 4
- 230000036541 health Effects 0.000 description 4
- -1 iron ions Chemical class 0.000 description 4
- 210000004072 lung Anatomy 0.000 description 4
- 229940035034 maltodextrin Drugs 0.000 description 4
- 238000004806 packaging method and process Methods 0.000 description 4
- 210000000952 spleen Anatomy 0.000 description 4
- 230000035900 sweating Effects 0.000 description 4
- 229940126680 traditional chinese medicines Drugs 0.000 description 4
- 235000010894 Artemisia argyi Nutrition 0.000 description 3
- 241000721047 Danaus plexippus Species 0.000 description 3
- 208000001431 Psychomotor Agitation Diseases 0.000 description 3
- 206010038743 Restlessness Diseases 0.000 description 3
- 244000030166 artemisia Species 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 3
- 239000000686 essence Substances 0.000 description 3
- 230000001737 promoting effect Effects 0.000 description 3
- 210000003491 skin Anatomy 0.000 description 3
- 206010010904 Convulsion Diseases 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- 239000004831 Hot glue Substances 0.000 description 2
- 239000004698 Polyethylene Substances 0.000 description 2
- 239000004743 Polypropylene Substances 0.000 description 2
- 241000405414 Rehmannia Species 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 208000031971 Yin Deficiency Diseases 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 239000000853 adhesive Substances 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
- 239000002390 adhesive tape Substances 0.000 description 2
- 230000002411 adverse Effects 0.000 description 2
- 210000001124 body fluid Anatomy 0.000 description 2
- 239000010839 body fluid Substances 0.000 description 2
- 230000004087 circulation Effects 0.000 description 2
- 230000003750 conditioning effect Effects 0.000 description 2
- 235000009508 confectionery Nutrition 0.000 description 2
- 230000036461 convulsion Effects 0.000 description 2
- 230000002950 deficient Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000002708 enhancing effect Effects 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 230000004438 eyesight Effects 0.000 description 2
- 239000004744 fabric Substances 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 230000001939 inductive effect Effects 0.000 description 2
- 229910052500 inorganic mineral Inorganic materials 0.000 description 2
- CDOSHBSSFJOMGT-UHFFFAOYSA-N linalool Chemical compound CC(C)=CCCC(C)(O)C=C CDOSHBSSFJOMGT-UHFFFAOYSA-N 0.000 description 2
- UWKAYLJWKGQEPM-LBPRGKRZSA-N linalyl acetate Chemical compound CC(C)=CCC[C@](C)(C=C)OC(C)=O UWKAYLJWKGQEPM-LBPRGKRZSA-N 0.000 description 2
- 239000011707 mineral Substances 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- 230000035764 nutrition Effects 0.000 description 2
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 2
- 229920000573 polyethylene Polymers 0.000 description 2
- 229920001155 polypropylene Polymers 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 238000010791 quenching Methods 0.000 description 2
- 230000000171 quenching effect Effects 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- 230000000638 stimulation Effects 0.000 description 2
- 238000005728 strengthening Methods 0.000 description 2
- 239000013589 supplement Substances 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- 238000003809 water extraction Methods 0.000 description 2
- 239000001490 (3R)-3,7-dimethylocta-1,6-dien-3-ol Substances 0.000 description 1
- DSSYKIVIOFKYAU-XCBNKYQSSA-N (R)-camphor Chemical compound C1C[C@@]2(C)C(=O)C[C@@H]1C2(C)C DSSYKIVIOFKYAU-XCBNKYQSSA-N 0.000 description 1
- CDOSHBSSFJOMGT-JTQLQIEISA-N (R)-linalool Natural products CC(C)=CCC[C@@](C)(O)C=C CDOSHBSSFJOMGT-JTQLQIEISA-N 0.000 description 1
- 244000061520 Angelica archangelica Species 0.000 description 1
- 241000045403 Astragalus propinquus Species 0.000 description 1
- 206010007247 Carbuncle Diseases 0.000 description 1
- 241000723346 Cinnamomum camphora Species 0.000 description 1
- 241000675108 Citrus tangerina Species 0.000 description 1
- 244000124209 Crocus sativus Species 0.000 description 1
- 235000015655 Crocus sativus Nutrition 0.000 description 1
- 208000015220 Febrile disease Diseases 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 235000001287 Guettarda speciosa Nutrition 0.000 description 1
- 240000005779 Jasminum multiflorum Species 0.000 description 1
- 244000062241 Kaempferia galanga Species 0.000 description 1
- 235000013421 Kaempferia galanga Nutrition 0.000 description 1
- 241000244365 Ligusticum sinense Species 0.000 description 1
- 241000112528 Ligusticum striatum Species 0.000 description 1
- 241000195954 Lycopodium clavatum Species 0.000 description 1
- 206010033557 Palpitations Diseases 0.000 description 1
- 240000002505 Pogostemon cablin Species 0.000 description 1
- 235000011751 Pogostemon cablin Nutrition 0.000 description 1
- 241000208966 Polygala Species 0.000 description 1
- 240000001341 Reynoutria japonica Species 0.000 description 1
- 235000018167 Reynoutria japonica Nutrition 0.000 description 1
- 241000304195 Salvia miltiorrhiza Species 0.000 description 1
- 235000011135 Salvia miltiorrhiza Nutrition 0.000 description 1
- 206010043376 Tetanus Diseases 0.000 description 1
- 244000273928 Zingiber officinale Species 0.000 description 1
- 235000006886 Zingiber officinale Nutrition 0.000 description 1
- 240000008866 Ziziphus nummularia Species 0.000 description 1
- 230000001133 acceleration Effects 0.000 description 1
- 238000001467 acupuncture Methods 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 235000006533 astragalus Nutrition 0.000 description 1
- 235000019606 astringent taste Nutrition 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- 229960000846 camphor Drugs 0.000 description 1
- 229930008380 camphor Natural products 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 239000003610 charcoal Substances 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 239000002274 desiccant Substances 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 230000000517 effect on sleep Effects 0.000 description 1
- 230000008451 emotion Effects 0.000 description 1
- 238000011841 epidemiological investigation Methods 0.000 description 1
- 206010015037 epilepsy Diseases 0.000 description 1
- 230000005284 excitation Effects 0.000 description 1
- 230000005281 excited state Effects 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 235000008397 ginger Nutrition 0.000 description 1
- 239000011086 glassine Substances 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 238000009499 grossing Methods 0.000 description 1
- 208000006454 hepatitis Diseases 0.000 description 1
- 208000021760 high fever Diseases 0.000 description 1
- 235000012907 honey Nutrition 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- XEEYBQQBJWHFJM-UHFFFAOYSA-N iron Substances [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- WTFXARWRTYJXII-UHFFFAOYSA-N iron(2+);iron(3+);oxygen(2-) Chemical compound [O-2].[O-2].[O-2].[O-2].[Fe+2].[Fe+3].[Fe+3] WTFXARWRTYJXII-UHFFFAOYSA-N 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 229930007744 linalool Natural products 0.000 description 1
- UWKAYLJWKGQEPM-UHFFFAOYSA-N linalool acetate Natural products CC(C)=CCCC(C)(C=C)OC(C)=O UWKAYLJWKGQEPM-UHFFFAOYSA-N 0.000 description 1
- 208000018191 liver inflammation Diseases 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 230000005906 menstruation Effects 0.000 description 1
- 230000006996 mental state Effects 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 230000036565 night sweats Effects 0.000 description 1
- 206010029410 night sweats Diseases 0.000 description 1
- 230000024121 nodulation Effects 0.000 description 1
- 230000003204 osmotic effect Effects 0.000 description 1
- 238000012536 packaging technology Methods 0.000 description 1
- 244000138993 panchioli Species 0.000 description 1
- 239000000123 paper Substances 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 239000012466 permeate Substances 0.000 description 1
- 239000011505 plaster Substances 0.000 description 1
- 206010036067 polydipsia Diseases 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 208000020016 psychiatric disease Diseases 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 230000036578 sleeping time Effects 0.000 description 1
- 235000019614 sour taste Nutrition 0.000 description 1
- 238000007619 statistical method Methods 0.000 description 1
- 210000000434 stratum corneum Anatomy 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 229910052613 tourmaline Inorganic materials 0.000 description 1
- 229940070527 tourmaline Drugs 0.000 description 1
- 239000011032 tourmaline Substances 0.000 description 1
- 239000005419 vinegar essence Substances 0.000 description 1
- 230000002618 waking effect Effects 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- 235000014101 wine Nutrition 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/69—Polygalaceae (Milkwort family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/79—Schisandraceae (Schisandra family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/009—Sachets, pouches characterised by the material or function of the envelope
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
- A61N2005/0659—Radiation therapy using light characterised by the wavelength of light used infrared
- A61N2005/066—Radiation therapy using light characterised by the wavelength of light used infrared far infrared
Abstract
A sleep-aiding foot patch comprises a medicine bag consisting of the following components: 30-80 parts by weight of sleep-aiding traditional Chinese medicine extract powder; 0.1-5 parts of lavender essential oil, 1-10 parts of far infrared ceramic powder, 5-40 parts of bamboo vinegar powder, 5-30 parts of magnetite powder and 1-15 parts of oyster powder; the traditional Chinese medicine extract powder for aiding sleep is prepared from the following raw materials: 5-50 parts of albizia flower, 1-20 parts of ginseng, 10-30 parts of radix rehmanniae, 10-40 parts of white peony root, 10-40 parts of schisandra chinensis, 10-40 parts of polygala tenuifolia, 2-80 parts of spina date seed, 10-40 parts of garden balsam stem, 10-50 parts of oyster and 10-50 parts of magnet. The foot patch has effects of relieving nerve, relaxing muscles and tendons, activating collaterals, dispersing stagnated liver qi, relieving qi stagnation, invigorating kidney, replenishing vital essence, improving blood circulation and metabolism, improving sleep quality and improving body state.
Description
Technical Field
The invention belongs to the field of health care products. In particular to a sleep-aiding foot patch.
Background
The theory of traditional Chinese medicine considers that the foot is the starting point of the three yin meridians of the foot and the end point of the three yang meridians of the foot, and the foot is connected with the whole body through the six meridians, so that the tradition of applying the sole to treat diseases and keep health in the ancient times has related records in a plurality of documents such as Huangdi's internal meridian, elbow backup emergency prescription, Qian jin Yao Fang and Wai Tai Mi Yao.
Due to the limitation of the preparation level, most of the ancient books record that the medicines are made into powder, then mixed into paste with water, yellow wine, vinegar, honey and the like, and applied to acupuncture points such as navel, sole and the like to play a role in treatment and health care. The operation is complex in the using process, the moisture is easy to lose in the using process, the transdermal absorption effect is poor after drying, and clothes and the like are easy to pollute.
With the progress of extraction and packaging technology, some people simply crush traditional Chinese medicines in China and then mix and package the traditional Chinese medicines to prepare commodities. For example:
201810722786.6A health foot patch is prepared from natural bamboo vinegar essence powder, bamboo charcoal powder, tourmaline, natural mineral micropowder, folium Artemisiae Argyi, tangerine pith essential oil, conch protein powder, lavender powder and flos Carthami. The preparation method comprises pulverizing the above materials into 120-140 mesh powder, mixing, and packaging into 6-8 g package.
201810230643.3 discloses a Chinese mugwort new foot patch, which comprises the following components: 450 parts of Chinese mugwort 410-containing material, 5-25 parts of ligusticum chuanxiong hort, 5-25 parts of astragalus membranaceus, 3-15 parts of saffron crocus, 5-25 parts of prepared rehmannia root, 10-30 parts of garden balsam stem, 1.1-5.2 parts of galangal, 1.8-9.3 parts of patchouli, 0.9-5.1 parts of dalbergia wood, 1.2-4.7 parts of rhizoma cyperi, 1.1-5.3 parts of dried orange peel, 1.1-5.1 parts of salvia miltiorrhiza, 1.2-5.3 parts of raw radix aconiti, 0.8-5.5 parts of angelica, 1.2-5.3 parts of Chinese starjasmine stem, 1.1-5.3 parts of tuber fleeceflower stem, 2.1-8.8 parts of lycopodium clavatum, 2.2-9 parts of caulis spatholobi, 2-9 parts of ligusticum wallichii, 1-5 parts of rhizoma ligustici wallichii, 1.1-5.2 parts of dried ginger peel and 0.3-1.5. The Chinese mugwort neopodia paste has the effects of clearing and activating the channels and collaterals, dispelling wind and removing dampness, and strengthening yang and consolidating the constitution.
The current method still comprises the steps of grinding the traditional Chinese medicines and additives into fine powder, and then mixing and packaging. Even if the traditional Chinese medicinal materials are crushed, the active ingredients in the traditional Chinese medicinal materials still exist in the tissues of the traditional Chinese medicinal materials and are difficult to be absorbed by the skin.
Disclosure of Invention
The invention provides a sleep-aiding foot patch which has the effects of relieving nerves, relaxing tendons, activating collaterals, soothing liver, relieving depression, tonifying kidney, replenishing vital essence, improving blood circulation, enhancing metabolism and the like, and can improve sleep quality and body state from multiple aspects.
In order to achieve the purpose, the invention comprises the following technical scheme:
a sleep-aiding foot patch comprises a medicine bag consisting of the following components: 30-80 parts by weight of sleep-aiding traditional Chinese medicine extract powder; 0.1-5 parts of lavender essential oil, 1-10 parts of far infrared ceramic powder, 5-40 parts of bamboo vinegar powder, 5-30 parts of magnetite powder and 1-15 parts of oyster powder;
the traditional Chinese medicine extract powder for aiding sleep is prepared from the following raw materials: 5-50 parts of albizia flower, 1-20 parts of ginseng, 10-30 parts of radix rehmanniae, 10-40 parts of white peony root, 10-40 parts of schisandra chinensis, 10-40 parts of polygala tenuifolia, 2-80 parts of spina date seed, 10-40 parts of garden balsam stem, 10-50 parts of oyster and 10-50 parts of magnet.
The sleep-aiding foot patch is preferably prepared from 35-75 parts by weight of sleep-aiding traditional Chinese medicine extract powder; 0.1-3 parts of lavender essential oil, 1-10 parts of far infrared ceramic powder, 10-30 parts of bamboo vinegar powder, 2-10 parts of oyster powder and 5-20 parts of magnetite powder.
The sleep-aiding foot patch is characterized in that preferably, 45-70 parts by weight of the sleep-aiding traditional Chinese medicine extract powder; 0.1-1 part of lavender essential oil, 1-10 parts of far infrared ceramic powder, 10-30 parts of bamboo vinegar powder, 2-10 parts of oyster powder and 5-20 parts of magnetite powder.
The sleep-aiding foot patch is preferably prepared from the following raw materials: 10-40 parts of albizia flower, 2-10 parts of ginseng, 10-30 parts of radix rehmanniae, 10-30 parts of white peony root, 10-30 parts of schisandra chinensis, 10-30 parts of polygala tenuifolia, 20-70 parts of spina date seed, 10-30 parts of garden balsam stem, 10-30 parts of oyster and 15-45 parts of magnet.
The sleep-aiding foot patch is preferably prepared from the following raw materials: 20-30 parts of albizia flower, 3-5 parts of ginseng, 15-20 parts of radix rehmanniae, 15-25 parts of white peony root, 15-20 parts of schisandra chinensis, 20-30 parts of polygala tenuifolia, 30-60 parts of spina date seed, 20-30 parts of garden balsam stem, 20-30 parts of oyster and 20-40 parts of magnet.
The sleep-aiding foot patch is preferably prepared by mixing the raw material medicines, extracting the mixture with hot water, concentrating the extracted liquid medicine, and drying to prepare an extract.
The sleep-aiding foot patch is preferably prepared from the sleep-aiding traditional Chinese medicine extract powder by the following method:
I. pulverizing flos Albizziae, Ginseng radix, radix rehmanniae, radix Paeoniae alba, fructus Schisandrae chinensis, cortex et radix Polygalae, semen Ziziphi Spinosae, caulis et folium Gaultheriae Yunnanensis, Concha Ostreae, and Magnetitum powder, and sieving with 40 mesh sieve;
weighing various medicinal powders according to the formula dosage, firstly adding oyster powder and magnetite powder into an extraction tank, adding deionized water with the weight 4-12 times that of the medicaments, heating to 85-100 ℃, keeping the temperature for 0.2-2 hours, then adding other medicinal powders, keeping the temperature for 0.2-2 hours, and then cooling to 40-60 ℃;
filtering dregs, adding deionized water 2-6 times of the weight of the medicine into the dregs, and extracting once according to the time and temperature conditions of the previous step;
and IV, concentrating the liquid medicine extracted twice, drying the liquid medicine into extract, crushing the extract, and sieving the crushed extract by a sieve of 80 meshes.
The sleep-aiding foot patch as described above, preferably, the particle size of the far infrared ceramic powder, oyster powder and magnet powder is 100 mesh or more.
In another aspect, the present invention provides a method for preparing a pharmaceutical pack of the sleep-aiding foot patch, the method comprising: adding the sleep-aiding traditional Chinese medicine extract powder, the lavender essential oil, the far infrared ceramic powder, the bamboo vinegar powder, the oyster powder and the magnetite powder into a mixer according to the proportion, stirring until the mixture is uniformly mixed, and then putting the mixture into a bag made of a heat-seal non-woven fabric material or a heat-seal paper material.
The lavender essential oil and bamboo vinegar powder can be prepared by a conventional method and can also be purchased in the market.
The foot patch comprises a plurality of traditional Chinese medicines, far infrared ceramic powder, lavender essential oil, bamboo vinegar powder, oyster powder and magnetite powder.
The lavender essential oil not only endows the product with elegant fragrance and has the functions of tranquilizing and allaying excitement and aiding sleep, but also contains rich linalool, linalyl acetate, camphor and other components, and the components have small molecular weight, are easy to permeate and absorb, can improve the permeability of stratum corneum and improve the permeation and absorption of other substances.
Magnetitum is salty and cold in nature, descending and sinking, calming the liver and subduing yang, improving hearing and eyesight, relieving convulsion and tranquilizing the mind, and absorbing qi and relieving asthma. When the health-care product is used in the product, the health-care product can help sleep, can tonify kidney essence, has the effects of improving hearing and eyesight, and directly improves the mental state when getting up the next day.
Mu Li has the actions of tranquilizing mind, pacifying liver and subduing yang, softening hardness and dissipating nodulation, astringing and inducing astringency. When used in the product, the product can also strengthen the heart and spirit and accelerate the sleeping speed.
The invention not only uses the original medicine powder of the oyster and the magnet, but also adds the oyster and the magnet in the preparation process of the extract because the oyster and the magnet are found in the research and development process of the product and have the synergistic effect. The sleep process can be obviously improved only by extracting the extract powder, and the sleep depth can be increased and the sleep quality can be improved after the original medicinal powder is added.
The albizia flower can sooth the liver and relieve depression, and relieve depression and melancholy and other adverse emotions of modern people caused by fast-paced life, so that people are happy and carefree, and sleep peacefully.
Ginseng is effective in invigorating primordial qi, restoring pulse, relieving depletion, invigorating spleen, benefiting lung, promoting fluid production, tranquilizing mind, and improving intelligence. Modern people generally have the problems of too fast life rhythm, short sleeping time and the like, and in addition, the exercise amount is less, the phenomenon of qi deficiency is common, the mind of a human body depends on qi and blood nourishing, and the mind is easy to cause insomnia due to the lack of nourishment caused by qi deficiency. Ginseng can supplement primordial qi, and insomnia can be relieved by qi and blood.
Radix rehmanniae clears heat and cools blood, and nourishes yin and promotes the production of body fluid. The disturbance of heart-mind by heat can lead to difficulty in falling asleep, dreaminess, etc., which is one of the important causes of sleep quality deterioration. In addition, TCM holds that "yang entering yin is sleep and yang exiting yin is the rule. The rehmannia root can clear heat and cool blood, prevent heat from disturbing heart spirit, nourish yin and promote the production of body fluid, and avoid insomnia caused by yang failing to enter yin.
White peony root: nourish blood and regulate menstruation, astringe yin and check sweating, soften liver and relieve pain, and calm liver yang. White peony root, radix Paeoniae alba nourishes blood and nourishes heart, and simultaneously it calms down liver yang and prevents the excessive excitation of heart-qi, makes heart quiet and easy to fall asleep.
Schisandra chinensis: astringe, tonify qi, nourish kidney, calm heart and induce tranquilization.
Wild jujube seed: nourish heart and nourish liver, induce tranquilization and check sweating. It is the key herb for nourishing heart and tranquilizing mind, and commonly indicated for various insomnia.
Polygala root: calm heart and induce tranquilization, remove phlegm and induce resuscitation, resolve carbuncle and swelling. Polygala tenuifolia is a good product for restoring normal coordination between heart and kidney, tranquilizing mind, improving intelligence and strengthening memory, because it can promote the circulation of heart-qi and calm the mind, and can promote the circulation of kidney-qi and strengthen the mind.
The garden balsam stem has the effects of dispelling wind and removing dampness, relaxing tendons and activating collaterals, promoting blood circulation and relieving pain and the like, can relieve discomfort such as aching, pain and swelling of muscles and bones caused by running in the day, relieves the influence of adverse stimulation on the rest effect, improves the sleep quality, improves the self-feeling after waking up, and improves the life quality of the next day.
The far infrared ceramic powder enters an excited state after being radiated by the far infrared rays of a human body, emits the far infrared rays with similar wave bands and feeds back the far infrared rays to the human body, so that the beneficial stimulation is provided for the use part of the human body, the blood flowing speed is accelerated, the local nutrition supply and the timely cleaning of metabolic waste are improved, the local environment is improved, and the rest effect is improved. Meanwhile, the acceleration of blood circulation can further improve the distribution speed of the active ingredients absorbed by permeation in vivo, and enhance and strengthen the conditioning effect of the foot patch.
The production process of the bamboo vinegar powder is derived from traditional Chinese medicine bamboo juice, which is liquid flowing out when bamboo is heated at high temperature, and has the effects of clearing heat, reducing pathogenic fire, smoothing phlegm and benefiting orifices due to the addition of various phenolic substances and the like. It is mainly used for treating phlegm retention in the middle-jiao, lung heat, infantile convulsion, epilepsy, excessive phlegm in febrile disease, high fever, polydipsia, vexation, tetanus, etc. Because of the large amount of acetic acid in it, it has obvious sour taste, so some people refer to it as bamboo vinegar. The significance of the bamboo vinegar powder used in the invention is that the bamboo vinegar contains small molecular acid such as acetic acid, etc., which can soften cuticle and promote the penetration and absorption of other active ingredients. Meanwhile, the acetic acid and the phenolic substances in the bamboo vinegar can inhibit the growth of fungi, local moist and rich nutrition environment is caused during the foot patch application period, the microorganism breeding is easily caused, and the trend can be effectively controlled by adding the bamboo vinegar powder.
The invention is based on the results of epidemiological investigation of the modern human body, and it is believed that insomnia is mostly caused by liver-blood deficiency and yin deficiency with internal heat. The liver stores blood and the heart stores spirit. Deficient liver blood failing to nourish the heart and yin deficiency generating internal heat can cause restlessness, insomnia and palpitation due to disturbance of deficient heat. The conditioning should be done by methods of nourishing blood, tranquillizing mind, clearing heat and relieving restlessness.
The spina date seed and the ginseng are used as monarch drugs in the formula, the spina date seed is sweet and sour, can enter heart and liver channels, nourish blood and liver, calm heart and tranquilize mind, the ginseng is sweet and neutral, enters heart, spleen and lung and channels, greatly tonifies primordial qi, tonifies spleen and lung, produces saliva and soothes the nerves, and the spina date seed and the ginseng are used together to tonify qi and blood, nourish heart and tonify liver and spleen to calm the nerves. Polygala tenuifolia has effects of calming heart, tranquilizing mind, eliminating phlegm and inducing resuscitation; the albizia flower relieves depression and soothes nerves; radix rehmanniae has effects of nourishing yin and clearing away heat; the white peony root, radix paeoniae alba and radix paeoniae alba nourish blood and regulate liver, astringe yin and stop sweating are used as ministerial drugs, are compatible with monarch drugs, have the effects of eliminating phlegm, resolving depression, clearing deficiency heat and nourishing liver blood to help tranquilize and relieve restlessness, and can clear deficiency heat and stop night sweat. The magnetite and the oyster are used for assisting in calming the nerves, calming the liver and suppressing yang, and subsiding the fire of heart and liver inflammation; the garden balsam stem has the effects of promoting blood circulation, removing obstruction in channels, dispelling wind and removing dampness; the schisandra chinensis has the effects of astringing, arresting discharge, tonifying kidney and calming heart, and the pungent powder and the acid powder are used together to supplement qi and promote blood circulation, nourish heart and regulate liver, clear heat and stop sweating in an adjuvant mode with monarch and minister medicines.
The beneficial effects of the invention are as follows:
(1) even if the medicine is pulverized into fine powder, it takes a long time for the active ingredients of the Chinese medicine to dissolve out of the fiber. The invention adopts water-soluble extraction, so that the active ingredients are completely separated from the constraint of plant fibers, and the invention is more favorable for osmotic absorption.
(2) The traditional Chinese medicine extract contains a certain amount of hydrophilic substances such as saccharides and proteins, and can absorb moisture exhaled by skin to be liquefied and dissolved and seep out of the packaging bag when being applied, and the moisture is directly acted on the surface of the skin, so that the permeation and absorption are further promoted.
(3) During the process of decocting, concentrating and drying the traditional Chinese medicine, the volatile oil contained in the traditional Chinese medicine is lost, and plant essential oil and other beneficial ingredients are added, so that the requirement of formula design is met.
(4) The traditional Chinese medicine extract powder for aiding sleep is prepared by mixing a plurality of traditional Chinese medicine raw materials and then carrying out water extraction, and researchers of the invention find that the effect of extracting the compound together is obviously better than that of single extraction. Generally, magnetite is considered to have poor water solubility, and generally has a very low extraction rate by simple water extraction, and in order to increase the extraction rate, magnetite is generally processed by vinegar quenching or the like. However, researchers find that the effect of the raw magnetite is better, probably because the iron ions of the magnetite after vinegar quenching are dissolved out too much, and the dissolution of active ingredients in other medicinal materials is influenced.
(5) The foot patch has the effects of relieving nerves, relaxing tendons, activating collaterals, soothing liver, relieving depression, tonifying kidney, replenishing vital essence, improving blood circulation, enhancing metabolism and the like, and can improve sleep quality and physical state from multiple aspects.
Detailed Description
The invention will be further illustrated with reference to the following specific examples. It should be understood that these examples are for illustrative purposes only and are not intended to limit the scope of the present invention.
The sources of some of the raw materials in the following examples are as follows:
far infrared ceramic powder: shanghai Ganna powder technology Co., Ltd
Lavender essential oil: beijing Peking Shih daily chemical Limited liability company
Bamboo vinegar powder: jiangyun Zhongju Biotech Co Ltd
Magnetic stone powder: lingshou county-Chuan new mineral processing factory
The preparation method of the sleep-aiding traditional Chinese medicine extract powder used in the following examples is as follows:
TABLE 1
1. The raw medicinal materials in the table 1 are inspected to be qualified and then are crushed into powder of 40 meshes.
2. Firstly weighing magnetite powder according to the formula dosage of the following table 1, adding water, heating to 98 ℃, preserving heat for 1 hour, then adding the rest medicinal powder, continuously preserving heat for 60 minutes, and cooling to 45 ℃.
3. Filtering out the residue by centrifuge. 800 kg of deionized water is added into the medicine residue, and the extraction is carried out once again according to the extraction conditions in the previous step.
4. Adding the liquid medicine extracted twice into a concentration tank, and concentrating to 200 liters.
5. Drying the concentrated liquid medicine in a microwave dryer to obtain extract.
6. The extract is crushed into 80 meshes, and two kinds of sleep-aiding traditional Chinese medicine extract powder, namely sleep-aiding traditional Chinese medicine extract powder (I) and sleep-aiding traditional Chinese medicine extract powder (II) are obtained respectively.
EXAMPLE 1 preparation of sleep-aid foot paste
1. The formula comprises the following components:
TABLE 2
Name of raw materials | Dosage (kg) |
Chinese medicine extract powder for helping sleep | 50.0 |
Far infrared ceramic powder | 4.5 |
Lavender essential oil | 0.5 |
Bamboo vinegar powder | 10.0 |
Magnetite powder | 15.0 |
Oyster powder | 5.0 |
2. Medicine bag for preparing sleep-aiding foot patch
Weighing the components according to the proportion in the table 1, adding the components into a mixer, stirring the components until the components are uniformly mixed, and then putting the components into a bag made of heat-seal non-woven fabric materials, namely the sleep-aiding foot patch medicine bag.
3. Non-woven adhesive cloth block for foot paste
One side of 50 g/square meter spunlace nonwoven fabric is coated with hot melt adhesive, 80 g/square meter glassine is adhered on the hot melt adhesive, the size of the fabric is 95mm multiplied by 120mm, and a straight line incision is formed at a position 1.5CM away from the short side.
4. Package (I)
The foot patch medicated bag is packaged into Polyethylene (PE) foot patch self-sealing bag, and the non-woven fabric adhesive plaster block is packaged into polypropylene (OPP) self-sealing bag. And (3) filling the foot patch valve bag, the adhesive tape block valve bag and the desiccant bag (the outer part is a non-woven bag, and the inner part is granular silicon dioxide) into a polypropylene packaging bag to obtain the sleep-aiding foot patch product.
EXAMPLE 2 preparation of sleep-aid foot paste (II)
A sleep-aiding foot patch was prepared in the same manner as in example 1, except that the formulation shown in table 3 was used:
TABLE 3
Name of raw materials | Dosage (kg) |
Chinese medicine extract powder for helping sleep | 70.0 |
Far infrared ceramic powder | 1.0 |
Lavender essential oil | 1.0 |
Bamboo vinegar powder | 20.0 |
Magnetite powder | 5.0 |
Oyster powder | 10.0 |
EXAMPLE 3 preparation of sleep-aid foot paste (III)
A sleep-aiding foot patch was prepared in the same manner as in example 1, except that the formulation shown in table 4 was used:
TABLE 4
Name of raw materials | Dosage (kg) |
Chinese medicine extract powder for helping sleep | 30.0 |
Far infrared ceramic powder | 10.0 |
Lavender essential oil | 0.3 |
Bamboo vinegar powder | 30 |
Magnetite powder | 19.7 |
Oyster powder | 2.0 |
EXAMPLE 4 preparation of sleep-aid foot paste (IV)
A sleep-aiding foot patch was prepared in the same manner as in example 1, except that the formulation shown in table 5 was used:
TABLE 5
Name of raw materials | Dosage (kg) |
Chinese medicine extract powder for helping sleep | 60.0 |
Far infrared ceramic powder | 15.0 |
Lavender essential oil | 0.1 |
Bamboo vinegar powder | 5.0 |
Magnetite powder | 14.9 |
Oyster powder | 3.0 |
Comparative example 1
A sleep-aiding foot patch was prepared in the same manner as in example 1, except that the formulation shown in table 6 was used:
TABLE 6
Name of raw materials | Dosage (kg) |
Chinese medicine extract powder for helping sleep | 50.0 |
Maltodextrin | 4.5 |
Far infrared potteryPorcelain powder | 0.0 |
Lavender essential oil | 0.5 |
Bamboo vinegar powder | 10.0 |
Magnetite powder | 15.0 |
Oyster powder | 5.0 |
Comparative example 2
A sleep-aiding foot patch was prepared in the same manner as in example 1, except that the formulation shown in table 7 was used:
TABLE 7
Name of raw materials | Dosage (kg) |
Chinese medicine extract powder for helping sleep | 50.0 |
Maltodextrin | 15.0 |
Far infrared ceramic powder | 4.5 |
Lavender essential oil | 0.5 |
Bamboo vinegar powder | 10.0 |
Magnetite powder | 0.0 |
Oyster powder | 5.0 |
Comparative example 3
A sleep-aiding foot patch was prepared in the same manner as in example 1, except that the formulation shown in table 8 was used:
TABLE 8
Name of raw materials | Dosage (kg) |
Chinese medicine extract powder for helping sleep | 50.0 |
Maltodextrin | 5.0 |
Far infrared ceramic powder | 4.5 |
Lavender essential oil | 0.5 |
Bamboo vinegar powder | 10.0 |
Magnetite powder | 15.0 |
Oyster powder | 0.0 |
Comparative example 4
A sleep-aiding foot patch was prepared in the same manner as in example 1, except that the formulation shown in table 9 was used:
TABLE 9
Name of raw materials | Dosage (kg) |
Chinese medicine extract powder for helping sleep | 0 |
Maltodextrin | 50.0 |
Far infrared ceramic powder | 4.5 |
Lavender essential oil | 0.5 |
Bamboo vinegar powder | 10.0 |
Magnetite powder | 15.0 |
Oyster powder | 5.0 |
Experimental example 1 Performance evaluation experiment
The foot patch products of examples 1 to 4 and comparative examples 1 to 4 were subjected to sleep-aid performance evaluation experiments, wherein 20 persons in each group were selected as volunteers under the following conditions: 1. age 18-75 years; 2. patients with insomnia were diagnosed according to the Chinese Classification and diagnosis of mental disorders (third edition, CCMD-3); 3. the disease course standard is as follows: at least 3 times per week for more than one month; PSQI > 7 points; 5. the vital signs are stable, the mind is clear, and certain expression capacity is realized; 6. insomnia due to non-organic lesions. If the conditions are met, the method can be selected.
The test method comprises the following steps: firstly, collecting the information related to the sleep of the testees, and grouping the testees according to the PSQI score. The foot is applied to the sole of the foot before sleeping every night, and the Yongquan acupoint is covered with adhesive tape, and removed the next morning before getting up, and the residual medicinal liquid is wiped off with wet towel. After six weeks of treatment for each group, subjects were re-evaluated for sleep effects in Pesburg based on the last month of sleep. Statistical analysis was performed using SPSS 23.0 software. The difference is statistically significant when P < 0.05. The comparative test results are shown in Table 10.
Watch 10
From the perspective of sleep treatment improvement effect, the treatment effect of the group in example 1 is the best, and the improvement degree of the sleep quality of comparative examples 1-4, in which no far infrared ceramic powder, magnetite powder, oyster powder or sleep-aiding traditional Chinese medicine extract powder is added in the formula, is not the same as that of the treatment group, so that the statistical significance is achieved.
It should be understood that the above-mentioned embodiments of the present invention are only examples for clearly illustrating the present invention, and are not intended to limit the embodiments of the present invention, and it will be obvious to those skilled in the art that other variations or modifications may be made on the basis of the above description, and all embodiments may not be exhaustive, and all obvious variations or modifications belonging to the technical solutions of the present invention are within the scope of the present invention.
Claims (9)
1. The sleep-aiding foot patch is characterized by comprising a medicine bag consisting of the following components: 30-80 parts by weight of sleep-aiding traditional Chinese medicine extract powder; 0.1-5 parts of lavender essential oil, 1-10 parts of far infrared ceramic powder, 5-40 parts of bamboo vinegar powder, 5-30 parts of magnetite powder and 1-15 parts of oyster powder;
the traditional Chinese medicine extract powder for aiding sleep is prepared from the following raw materials: 5-50 parts of albizia flower, 1-20 parts of ginseng, 10-30 parts of radix rehmanniae, 10-40 parts of white peony root, 10-40 parts of schisandra chinensis, 10-40 parts of polygala tenuifolia, 2-80 parts of spina date seed, 10-40 parts of garden balsam stem, 10-50 parts of oyster and 10-50 parts of magnet.
2. The sleep-aiding foot patch as claimed in claim 1, wherein 35-75 parts by weight of the sleep-aiding traditional Chinese medicine extract powder; 0.1-3 parts of lavender essential oil, 1-10 parts of far infrared ceramic powder, 10-30 parts of bamboo vinegar powder, 2-10 parts of oyster powder and 5-20 parts of magnetite powder.
3. The sleep-aiding foot patch as claimed in claim 2, wherein 45-70 parts by weight of the sleep-aiding traditional Chinese medicine extract powder; 0.1-1 part of lavender essential oil, 1-10 parts of far infrared ceramic powder, 10-30 parts of bamboo vinegar powder, 2-10 parts of oyster powder and 5-20 parts of magnetite powder.
4. The sleep-aiding foot patch as claimed in any one of claims 1 to 3, wherein the sleep-aiding Chinese medicinal extract powder is prepared from the following raw materials: 10-40 parts of albizia flower, 2-10 parts of ginseng, 10-30 parts of radix rehmanniae, 10-30 parts of white peony root, 10-30 parts of schisandra chinensis, 10-30 parts of polygala tenuifolia, 20-70 parts of spina date seed, 10-30 parts of garden balsam stem, 10-30 parts of oyster and 15-45 parts of magnet.
5. The sleep-aiding foot patch as claimed in claim 4, wherein the sleep-aiding traditional Chinese medicine extract powder is prepared from the following raw materials: 20-30 parts of albizia flower, 3-5 parts of ginseng, 15-20 parts of radix rehmanniae, 15-25 parts of white peony root, 15-20 parts of schisandra chinensis, 20-30 parts of polygala tenuifolia, 30-60 parts of spina date seed, 20-30 parts of garden balsam stem, 20-30 parts of oyster and 20-40 parts of magnet.
6. The sleep-aiding foot patch as claimed in any one of claims 1 to 5, wherein the sleep-aiding traditional Chinese medicine extract powder is prepared by mixing the raw material medicines, extracting the raw material medicines with hot water, concentrating the extracted liquid medicine, and drying the concentrated liquid medicine to prepare an extract.
7. The sleep-aiding foot patch as claimed in claim 6, wherein the sleep-aiding traditional Chinese medicine extract powder is prepared by the following method:
I. pulverizing flos Albizziae, Ginseng radix, radix rehmanniae, radix Paeoniae alba, fructus Schisandrae chinensis, cortex et radix Polygalae, semen Ziziphi Spinosae, caulis et folium Gaultheriae Yunnanensis, Concha Ostreae, and Magnetitum powder, and sieving with 40 mesh sieve;
weighing various medicinal powders according to the formula dosage, firstly adding oyster powder and magnetite powder into an extraction tank, adding deionized water with the weight 4-12 times that of the medicaments, heating to 85-100 ℃, keeping the temperature for 0.2-2 hours, then adding other medicinal powders, keeping the temperature for 0.2-2 hours, and then cooling to 40-60 ℃;
filtering dregs, adding deionized water 2-6 times of the weight of the medicine into the dregs, and extracting once according to the time and temperature conditions of the previous step;
and IV, concentrating the liquid medicine extracted twice, drying the liquid medicine into extract, crushing the extract, and sieving the crushed extract by a sieve of 80 meshes.
8. The sleep-aiding foot patch as claimed in claim 1, wherein the particle size of the far infrared ceramic powder, oyster powder and magnet powder is more than 100 meshes.
9. A method of making a sleep aid foot patch package according to any one of claims 1 to 8, comprising: adding the sleep-aiding traditional Chinese medicine extract powder, the lavender essential oil, the far infrared ceramic powder, the bamboo vinegar powder, the oyster powder and the magnetite powder into a mixer according to the proportion, stirring until the mixture is uniformly mixed, and then putting the mixture into a bag made of a heat-seal non-woven fabric material or a heat-seal paper material.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202010629245.6A CN111840405A (en) | 2020-07-02 | 2020-07-02 | Sleep-aiding foot patch and preparation method thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202010629245.6A CN111840405A (en) | 2020-07-02 | 2020-07-02 | Sleep-aiding foot patch and preparation method thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
CN111840405A true CN111840405A (en) | 2020-10-30 |
Family
ID=73152606
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202010629245.6A Pending CN111840405A (en) | 2020-07-02 | 2020-07-02 | Sleep-aiding foot patch and preparation method thereof |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN111840405A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112791155A (en) * | 2021-01-08 | 2021-05-14 | 国珍健康科技(北京)有限公司 | Rose foot patch and preparation method thereof |
CN112891470A (en) * | 2021-01-28 | 2021-06-04 | 国珍健康科技(北京)有限公司 | Wormwood foot patch and preparation method thereof |
CN112972610A (en) * | 2021-03-22 | 2021-06-18 | 国珍健康科技(北京)有限公司 | Evodia rutaecarpa foot patch and preparation method thereof |
-
2020
- 2020-07-02 CN CN202010629245.6A patent/CN111840405A/en active Pending
Non-Patent Citations (1)
Title |
---|
1993308389: "Q_NSY072-2017薰衣草足贴最新", 《HTTPS://WWW.DOC88.COM/P-3867854324965.HTML》 * |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112791155A (en) * | 2021-01-08 | 2021-05-14 | 国珍健康科技(北京)有限公司 | Rose foot patch and preparation method thereof |
CN112891470A (en) * | 2021-01-28 | 2021-06-04 | 国珍健康科技(北京)有限公司 | Wormwood foot patch and preparation method thereof |
CN112972610A (en) * | 2021-03-22 | 2021-06-18 | 国珍健康科技(北京)有限公司 | Evodia rutaecarpa foot patch and preparation method thereof |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN102078520B (en) | Chinese medicinal preparation for treating nervous headache and preparation method thereof | |
CN104305788B (en) | A kind of Flos Chrysanthemi Indici mind easing tea health-care medicine pillow and preparation method thereof | |
CN111110898A (en) | Herbal original dew atomized liquid with essence | |
CN111840405A (en) | Sleep-aiding foot patch and preparation method thereof | |
CN104586669A (en) | Fat-reducing externally-applied cream | |
CN106880782A (en) | Disease-relieving and physique enhancing medicine-filled pillow | |
CN103566202A (en) | Traditional Chinese medicine conducive to sleep | |
CN111150822A (en) | Multifunctional herbal essence atomized liquid | |
CN104666896A (en) | Orally-taken medicine for treating alopecia seborrhoeica and preparation method for orally-taken medicine | |
CN108315185B (en) | Health wine for dispelling cold and tonifying kidney and preparation method thereof | |
CN108126160B (en) | Traditional Chinese medicine composition, traditional Chinese medicine health tea, preparation method and application thereof | |
CN104958429A (en) | Traditional Chinese medicinal composition for treating geriatric fracture and preparation method thereof | |
CN109674704A (en) | A kind of Chinese medicine bathing antibacterial liquid/particle improving damp-heat constitution and preparation and application method | |
CN108355038A (en) | The Chinese medicine bathing instant granular of improvement qi deficiency to blood stasis rheumatism and preparation and application method | |
CN112891470A (en) | Wormwood foot patch and preparation method thereof | |
KR20150122302A (en) | Herbal composition, method for producing therof and method for use therof | |
CN105617330A (en) | External essential oil for quickly eliminating skin inflammation | |
CN105920379A (en) | Traditional Chinese medicine eye cream to alleviate pouch and preparation method thereof | |
CN105919907A (en) | Manufacturing method of traditional Chinese medicine eye cream and eye cream | |
CN105343660A (en) | Traditional Chinese medicinal preparation for treating peripheral vertigo and preparation method of traditional Chinese medicinal preparation | |
CN104906252A (en) | Traditional Chinese medicine for treating gray hair | |
CN104548020A (en) | Application of medicine composition in preparing medicine curing senile dementia | |
CN104083311A (en) | Natural plant-derived functional massage lotion | |
CN112043811A (en) | Radix morindae officinalis and radix gastrodiae patch and preparation method thereof | |
CN112791155A (en) | Rose foot patch and preparation method thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20201030 |
|
RJ01 | Rejection of invention patent application after publication |