CN111840405A - Sleep-aiding foot patch and preparation method thereof - Google Patents

Sleep-aiding foot patch and preparation method thereof Download PDF

Info

Publication number
CN111840405A
CN111840405A CN202010629245.6A CN202010629245A CN111840405A CN 111840405 A CN111840405 A CN 111840405A CN 202010629245 A CN202010629245 A CN 202010629245A CN 111840405 A CN111840405 A CN 111840405A
Authority
CN
China
Prior art keywords
parts
powder
sleep
aiding
oyster
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202010629245.6A
Other languages
Chinese (zh)
Inventor
张莹
李永强
彭金乱
魏昊
孙流生
李爱民
李颖
邢岩
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guozhen Health Technology Beijing Co ltd
Original Assignee
Guozhen Health Technology Beijing Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guozhen Health Technology Beijing Co ltd filed Critical Guozhen Health Technology Beijing Co ltd
Priority to CN202010629245.6A priority Critical patent/CN111840405A/en
Publication of CN111840405A publication Critical patent/CN111840405A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/26Iron; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/69Polygalaceae (Milkwort family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725Ziziphus, e.g. jujube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/79Schisandraceae (Schisandra family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/009Sachets, pouches characterised by the material or function of the envelope
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0658Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0659Radiation therapy using light characterised by the wavelength of light used infrared
    • A61N2005/066Radiation therapy using light characterised by the wavelength of light used infrared far infrared

Abstract

A sleep-aiding foot patch comprises a medicine bag consisting of the following components: 30-80 parts by weight of sleep-aiding traditional Chinese medicine extract powder; 0.1-5 parts of lavender essential oil, 1-10 parts of far infrared ceramic powder, 5-40 parts of bamboo vinegar powder, 5-30 parts of magnetite powder and 1-15 parts of oyster powder; the traditional Chinese medicine extract powder for aiding sleep is prepared from the following raw materials: 5-50 parts of albizia flower, 1-20 parts of ginseng, 10-30 parts of radix rehmanniae, 10-40 parts of white peony root, 10-40 parts of schisandra chinensis, 10-40 parts of polygala tenuifolia, 2-80 parts of spina date seed, 10-40 parts of garden balsam stem, 10-50 parts of oyster and 10-50 parts of magnet. The foot patch has effects of relieving nerve, relaxing muscles and tendons, activating collaterals, dispersing stagnated liver qi, relieving qi stagnation, invigorating kidney, replenishing vital essence, improving blood circulation and metabolism, improving sleep quality and improving body state.

Description

Sleep-aiding foot patch and preparation method thereof
Technical Field
The invention belongs to the field of health care products. In particular to a sleep-aiding foot patch.
Background
The theory of traditional Chinese medicine considers that the foot is the starting point of the three yin meridians of the foot and the end point of the three yang meridians of the foot, and the foot is connected with the whole body through the six meridians, so that the tradition of applying the sole to treat diseases and keep health in the ancient times has related records in a plurality of documents such as Huangdi's internal meridian, elbow backup emergency prescription, Qian jin Yao Fang and Wai Tai Mi Yao.
Due to the limitation of the preparation level, most of the ancient books record that the medicines are made into powder, then mixed into paste with water, yellow wine, vinegar, honey and the like, and applied to acupuncture points such as navel, sole and the like to play a role in treatment and health care. The operation is complex in the using process, the moisture is easy to lose in the using process, the transdermal absorption effect is poor after drying, and clothes and the like are easy to pollute.
With the progress of extraction and packaging technology, some people simply crush traditional Chinese medicines in China and then mix and package the traditional Chinese medicines to prepare commodities. For example:
201810722786.6A health foot patch is prepared from natural bamboo vinegar essence powder, bamboo charcoal powder, tourmaline, natural mineral micropowder, folium Artemisiae Argyi, tangerine pith essential oil, conch protein powder, lavender powder and flos Carthami. The preparation method comprises pulverizing the above materials into 120-140 mesh powder, mixing, and packaging into 6-8 g package.
201810230643.3 discloses a Chinese mugwort new foot patch, which comprises the following components: 450 parts of Chinese mugwort 410-containing material, 5-25 parts of ligusticum chuanxiong hort, 5-25 parts of astragalus membranaceus, 3-15 parts of saffron crocus, 5-25 parts of prepared rehmannia root, 10-30 parts of garden balsam stem, 1.1-5.2 parts of galangal, 1.8-9.3 parts of patchouli, 0.9-5.1 parts of dalbergia wood, 1.2-4.7 parts of rhizoma cyperi, 1.1-5.3 parts of dried orange peel, 1.1-5.1 parts of salvia miltiorrhiza, 1.2-5.3 parts of raw radix aconiti, 0.8-5.5 parts of angelica, 1.2-5.3 parts of Chinese starjasmine stem, 1.1-5.3 parts of tuber fleeceflower stem, 2.1-8.8 parts of lycopodium clavatum, 2.2-9 parts of caulis spatholobi, 2-9 parts of ligusticum wallichii, 1-5 parts of rhizoma ligustici wallichii, 1.1-5.2 parts of dried ginger peel and 0.3-1.5. The Chinese mugwort neopodia paste has the effects of clearing and activating the channels and collaterals, dispelling wind and removing dampness, and strengthening yang and consolidating the constitution.
The current method still comprises the steps of grinding the traditional Chinese medicines and additives into fine powder, and then mixing and packaging. Even if the traditional Chinese medicinal materials are crushed, the active ingredients in the traditional Chinese medicinal materials still exist in the tissues of the traditional Chinese medicinal materials and are difficult to be absorbed by the skin.
Disclosure of Invention
The invention provides a sleep-aiding foot patch which has the effects of relieving nerves, relaxing tendons, activating collaterals, soothing liver, relieving depression, tonifying kidney, replenishing vital essence, improving blood circulation, enhancing metabolism and the like, and can improve sleep quality and body state from multiple aspects.
In order to achieve the purpose, the invention comprises the following technical scheme:
a sleep-aiding foot patch comprises a medicine bag consisting of the following components: 30-80 parts by weight of sleep-aiding traditional Chinese medicine extract powder; 0.1-5 parts of lavender essential oil, 1-10 parts of far infrared ceramic powder, 5-40 parts of bamboo vinegar powder, 5-30 parts of magnetite powder and 1-15 parts of oyster powder;
the traditional Chinese medicine extract powder for aiding sleep is prepared from the following raw materials: 5-50 parts of albizia flower, 1-20 parts of ginseng, 10-30 parts of radix rehmanniae, 10-40 parts of white peony root, 10-40 parts of schisandra chinensis, 10-40 parts of polygala tenuifolia, 2-80 parts of spina date seed, 10-40 parts of garden balsam stem, 10-50 parts of oyster and 10-50 parts of magnet.
The sleep-aiding foot patch is preferably prepared from 35-75 parts by weight of sleep-aiding traditional Chinese medicine extract powder; 0.1-3 parts of lavender essential oil, 1-10 parts of far infrared ceramic powder, 10-30 parts of bamboo vinegar powder, 2-10 parts of oyster powder and 5-20 parts of magnetite powder.
The sleep-aiding foot patch is characterized in that preferably, 45-70 parts by weight of the sleep-aiding traditional Chinese medicine extract powder; 0.1-1 part of lavender essential oil, 1-10 parts of far infrared ceramic powder, 10-30 parts of bamboo vinegar powder, 2-10 parts of oyster powder and 5-20 parts of magnetite powder.
The sleep-aiding foot patch is preferably prepared from the following raw materials: 10-40 parts of albizia flower, 2-10 parts of ginseng, 10-30 parts of radix rehmanniae, 10-30 parts of white peony root, 10-30 parts of schisandra chinensis, 10-30 parts of polygala tenuifolia, 20-70 parts of spina date seed, 10-30 parts of garden balsam stem, 10-30 parts of oyster and 15-45 parts of magnet.
The sleep-aiding foot patch is preferably prepared from the following raw materials: 20-30 parts of albizia flower, 3-5 parts of ginseng, 15-20 parts of radix rehmanniae, 15-25 parts of white peony root, 15-20 parts of schisandra chinensis, 20-30 parts of polygala tenuifolia, 30-60 parts of spina date seed, 20-30 parts of garden balsam stem, 20-30 parts of oyster and 20-40 parts of magnet.
The sleep-aiding foot patch is preferably prepared by mixing the raw material medicines, extracting the mixture with hot water, concentrating the extracted liquid medicine, and drying to prepare an extract.
The sleep-aiding foot patch is preferably prepared from the sleep-aiding traditional Chinese medicine extract powder by the following method:
I. pulverizing flos Albizziae, Ginseng radix, radix rehmanniae, radix Paeoniae alba, fructus Schisandrae chinensis, cortex et radix Polygalae, semen Ziziphi Spinosae, caulis et folium Gaultheriae Yunnanensis, Concha Ostreae, and Magnetitum powder, and sieving with 40 mesh sieve;
weighing various medicinal powders according to the formula dosage, firstly adding oyster powder and magnetite powder into an extraction tank, adding deionized water with the weight 4-12 times that of the medicaments, heating to 85-100 ℃, keeping the temperature for 0.2-2 hours, then adding other medicinal powders, keeping the temperature for 0.2-2 hours, and then cooling to 40-60 ℃;
filtering dregs, adding deionized water 2-6 times of the weight of the medicine into the dregs, and extracting once according to the time and temperature conditions of the previous step;
and IV, concentrating the liquid medicine extracted twice, drying the liquid medicine into extract, crushing the extract, and sieving the crushed extract by a sieve of 80 meshes.
The sleep-aiding foot patch as described above, preferably, the particle size of the far infrared ceramic powder, oyster powder and magnet powder is 100 mesh or more.
In another aspect, the present invention provides a method for preparing a pharmaceutical pack of the sleep-aiding foot patch, the method comprising: adding the sleep-aiding traditional Chinese medicine extract powder, the lavender essential oil, the far infrared ceramic powder, the bamboo vinegar powder, the oyster powder and the magnetite powder into a mixer according to the proportion, stirring until the mixture is uniformly mixed, and then putting the mixture into a bag made of a heat-seal non-woven fabric material or a heat-seal paper material.
The lavender essential oil and bamboo vinegar powder can be prepared by a conventional method and can also be purchased in the market.
The foot patch comprises a plurality of traditional Chinese medicines, far infrared ceramic powder, lavender essential oil, bamboo vinegar powder, oyster powder and magnetite powder.
The lavender essential oil not only endows the product with elegant fragrance and has the functions of tranquilizing and allaying excitement and aiding sleep, but also contains rich linalool, linalyl acetate, camphor and other components, and the components have small molecular weight, are easy to permeate and absorb, can improve the permeability of stratum corneum and improve the permeation and absorption of other substances.
Magnetitum is salty and cold in nature, descending and sinking, calming the liver and subduing yang, improving hearing and eyesight, relieving convulsion and tranquilizing the mind, and absorbing qi and relieving asthma. When the health-care product is used in the product, the health-care product can help sleep, can tonify kidney essence, has the effects of improving hearing and eyesight, and directly improves the mental state when getting up the next day.
Mu Li has the actions of tranquilizing mind, pacifying liver and subduing yang, softening hardness and dissipating nodulation, astringing and inducing astringency. When used in the product, the product can also strengthen the heart and spirit and accelerate the sleeping speed.
The invention not only uses the original medicine powder of the oyster and the magnet, but also adds the oyster and the magnet in the preparation process of the extract because the oyster and the magnet are found in the research and development process of the product and have the synergistic effect. The sleep process can be obviously improved only by extracting the extract powder, and the sleep depth can be increased and the sleep quality can be improved after the original medicinal powder is added.
The albizia flower can sooth the liver and relieve depression, and relieve depression and melancholy and other adverse emotions of modern people caused by fast-paced life, so that people are happy and carefree, and sleep peacefully.
Ginseng is effective in invigorating primordial qi, restoring pulse, relieving depletion, invigorating spleen, benefiting lung, promoting fluid production, tranquilizing mind, and improving intelligence. Modern people generally have the problems of too fast life rhythm, short sleeping time and the like, and in addition, the exercise amount is less, the phenomenon of qi deficiency is common, the mind of a human body depends on qi and blood nourishing, and the mind is easy to cause insomnia due to the lack of nourishment caused by qi deficiency. Ginseng can supplement primordial qi, and insomnia can be relieved by qi and blood.
Radix rehmanniae clears heat and cools blood, and nourishes yin and promotes the production of body fluid. The disturbance of heart-mind by heat can lead to difficulty in falling asleep, dreaminess, etc., which is one of the important causes of sleep quality deterioration. In addition, TCM holds that "yang entering yin is sleep and yang exiting yin is the rule. The rehmannia root can clear heat and cool blood, prevent heat from disturbing heart spirit, nourish yin and promote the production of body fluid, and avoid insomnia caused by yang failing to enter yin.
White peony root: nourish blood and regulate menstruation, astringe yin and check sweating, soften liver and relieve pain, and calm liver yang. White peony root, radix Paeoniae alba nourishes blood and nourishes heart, and simultaneously it calms down liver yang and prevents the excessive excitation of heart-qi, makes heart quiet and easy to fall asleep.
Schisandra chinensis: astringe, tonify qi, nourish kidney, calm heart and induce tranquilization.
Wild jujube seed: nourish heart and nourish liver, induce tranquilization and check sweating. It is the key herb for nourishing heart and tranquilizing mind, and commonly indicated for various insomnia.
Polygala root: calm heart and induce tranquilization, remove phlegm and induce resuscitation, resolve carbuncle and swelling. Polygala tenuifolia is a good product for restoring normal coordination between heart and kidney, tranquilizing mind, improving intelligence and strengthening memory, because it can promote the circulation of heart-qi and calm the mind, and can promote the circulation of kidney-qi and strengthen the mind.
The garden balsam stem has the effects of dispelling wind and removing dampness, relaxing tendons and activating collaterals, promoting blood circulation and relieving pain and the like, can relieve discomfort such as aching, pain and swelling of muscles and bones caused by running in the day, relieves the influence of adverse stimulation on the rest effect, improves the sleep quality, improves the self-feeling after waking up, and improves the life quality of the next day.
The far infrared ceramic powder enters an excited state after being radiated by the far infrared rays of a human body, emits the far infrared rays with similar wave bands and feeds back the far infrared rays to the human body, so that the beneficial stimulation is provided for the use part of the human body, the blood flowing speed is accelerated, the local nutrition supply and the timely cleaning of metabolic waste are improved, the local environment is improved, and the rest effect is improved. Meanwhile, the acceleration of blood circulation can further improve the distribution speed of the active ingredients absorbed by permeation in vivo, and enhance and strengthen the conditioning effect of the foot patch.
The production process of the bamboo vinegar powder is derived from traditional Chinese medicine bamboo juice, which is liquid flowing out when bamboo is heated at high temperature, and has the effects of clearing heat, reducing pathogenic fire, smoothing phlegm and benefiting orifices due to the addition of various phenolic substances and the like. It is mainly used for treating phlegm retention in the middle-jiao, lung heat, infantile convulsion, epilepsy, excessive phlegm in febrile disease, high fever, polydipsia, vexation, tetanus, etc. Because of the large amount of acetic acid in it, it has obvious sour taste, so some people refer to it as bamboo vinegar. The significance of the bamboo vinegar powder used in the invention is that the bamboo vinegar contains small molecular acid such as acetic acid, etc., which can soften cuticle and promote the penetration and absorption of other active ingredients. Meanwhile, the acetic acid and the phenolic substances in the bamboo vinegar can inhibit the growth of fungi, local moist and rich nutrition environment is caused during the foot patch application period, the microorganism breeding is easily caused, and the trend can be effectively controlled by adding the bamboo vinegar powder.
The invention is based on the results of epidemiological investigation of the modern human body, and it is believed that insomnia is mostly caused by liver-blood deficiency and yin deficiency with internal heat. The liver stores blood and the heart stores spirit. Deficient liver blood failing to nourish the heart and yin deficiency generating internal heat can cause restlessness, insomnia and palpitation due to disturbance of deficient heat. The conditioning should be done by methods of nourishing blood, tranquillizing mind, clearing heat and relieving restlessness.
The spina date seed and the ginseng are used as monarch drugs in the formula, the spina date seed is sweet and sour, can enter heart and liver channels, nourish blood and liver, calm heart and tranquilize mind, the ginseng is sweet and neutral, enters heart, spleen and lung and channels, greatly tonifies primordial qi, tonifies spleen and lung, produces saliva and soothes the nerves, and the spina date seed and the ginseng are used together to tonify qi and blood, nourish heart and tonify liver and spleen to calm the nerves. Polygala tenuifolia has effects of calming heart, tranquilizing mind, eliminating phlegm and inducing resuscitation; the albizia flower relieves depression and soothes nerves; radix rehmanniae has effects of nourishing yin and clearing away heat; the white peony root, radix paeoniae alba and radix paeoniae alba nourish blood and regulate liver, astringe yin and stop sweating are used as ministerial drugs, are compatible with monarch drugs, have the effects of eliminating phlegm, resolving depression, clearing deficiency heat and nourishing liver blood to help tranquilize and relieve restlessness, and can clear deficiency heat and stop night sweat. The magnetite and the oyster are used for assisting in calming the nerves, calming the liver and suppressing yang, and subsiding the fire of heart and liver inflammation; the garden balsam stem has the effects of promoting blood circulation, removing obstruction in channels, dispelling wind and removing dampness; the schisandra chinensis has the effects of astringing, arresting discharge, tonifying kidney and calming heart, and the pungent powder and the acid powder are used together to supplement qi and promote blood circulation, nourish heart and regulate liver, clear heat and stop sweating in an adjuvant mode with monarch and minister medicines.
The beneficial effects of the invention are as follows:
(1) even if the medicine is pulverized into fine powder, it takes a long time for the active ingredients of the Chinese medicine to dissolve out of the fiber. The invention adopts water-soluble extraction, so that the active ingredients are completely separated from the constraint of plant fibers, and the invention is more favorable for osmotic absorption.
(2) The traditional Chinese medicine extract contains a certain amount of hydrophilic substances such as saccharides and proteins, and can absorb moisture exhaled by skin to be liquefied and dissolved and seep out of the packaging bag when being applied, and the moisture is directly acted on the surface of the skin, so that the permeation and absorption are further promoted.
(3) During the process of decocting, concentrating and drying the traditional Chinese medicine, the volatile oil contained in the traditional Chinese medicine is lost, and plant essential oil and other beneficial ingredients are added, so that the requirement of formula design is met.
(4) The traditional Chinese medicine extract powder for aiding sleep is prepared by mixing a plurality of traditional Chinese medicine raw materials and then carrying out water extraction, and researchers of the invention find that the effect of extracting the compound together is obviously better than that of single extraction. Generally, magnetite is considered to have poor water solubility, and generally has a very low extraction rate by simple water extraction, and in order to increase the extraction rate, magnetite is generally processed by vinegar quenching or the like. However, researchers find that the effect of the raw magnetite is better, probably because the iron ions of the magnetite after vinegar quenching are dissolved out too much, and the dissolution of active ingredients in other medicinal materials is influenced.
(5) The foot patch has the effects of relieving nerves, relaxing tendons, activating collaterals, soothing liver, relieving depression, tonifying kidney, replenishing vital essence, improving blood circulation, enhancing metabolism and the like, and can improve sleep quality and physical state from multiple aspects.
Detailed Description
The invention will be further illustrated with reference to the following specific examples. It should be understood that these examples are for illustrative purposes only and are not intended to limit the scope of the present invention.
The sources of some of the raw materials in the following examples are as follows:
far infrared ceramic powder: shanghai Ganna powder technology Co., Ltd
Lavender essential oil: beijing Peking Shih daily chemical Limited liability company
Bamboo vinegar powder: jiangyun Zhongju Biotech Co Ltd
Magnetic stone powder: lingshou county-Chuan new mineral processing factory
The preparation method of the sleep-aiding traditional Chinese medicine extract powder used in the following examples is as follows:
TABLE 1
Figure BDA0002567542620000061
1. The raw medicinal materials in the table 1 are inspected to be qualified and then are crushed into powder of 40 meshes.
2. Firstly weighing magnetite powder according to the formula dosage of the following table 1, adding water, heating to 98 ℃, preserving heat for 1 hour, then adding the rest medicinal powder, continuously preserving heat for 60 minutes, and cooling to 45 ℃.
3. Filtering out the residue by centrifuge. 800 kg of deionized water is added into the medicine residue, and the extraction is carried out once again according to the extraction conditions in the previous step.
4. Adding the liquid medicine extracted twice into a concentration tank, and concentrating to 200 liters.
5. Drying the concentrated liquid medicine in a microwave dryer to obtain extract.
6. The extract is crushed into 80 meshes, and two kinds of sleep-aiding traditional Chinese medicine extract powder, namely sleep-aiding traditional Chinese medicine extract powder (I) and sleep-aiding traditional Chinese medicine extract powder (II) are obtained respectively.
EXAMPLE 1 preparation of sleep-aid foot paste
1. The formula comprises the following components:
TABLE 2
Name of raw materials Dosage (kg)
Chinese medicine extract powder for helping sleep 50.0
Far infrared ceramic powder 4.5
Lavender essential oil 0.5
Bamboo vinegar powder 10.0
Magnetite powder 15.0
Oyster powder 5.0
2. Medicine bag for preparing sleep-aiding foot patch
Weighing the components according to the proportion in the table 1, adding the components into a mixer, stirring the components until the components are uniformly mixed, and then putting the components into a bag made of heat-seal non-woven fabric materials, namely the sleep-aiding foot patch medicine bag.
3. Non-woven adhesive cloth block for foot paste
One side of 50 g/square meter spunlace nonwoven fabric is coated with hot melt adhesive, 80 g/square meter glassine is adhered on the hot melt adhesive, the size of the fabric is 95mm multiplied by 120mm, and a straight line incision is formed at a position 1.5CM away from the short side.
4. Package (I)
The foot patch medicated bag is packaged into Polyethylene (PE) foot patch self-sealing bag, and the non-woven fabric adhesive plaster block is packaged into polypropylene (OPP) self-sealing bag. And (3) filling the foot patch valve bag, the adhesive tape block valve bag and the desiccant bag (the outer part is a non-woven bag, and the inner part is granular silicon dioxide) into a polypropylene packaging bag to obtain the sleep-aiding foot patch product.
EXAMPLE 2 preparation of sleep-aid foot paste (II)
A sleep-aiding foot patch was prepared in the same manner as in example 1, except that the formulation shown in table 3 was used:
TABLE 3
Name of raw materials Dosage (kg)
Chinese medicine extract powder for helping sleep 70.0
Far infrared ceramic powder 1.0
Lavender essential oil 1.0
Bamboo vinegar powder 20.0
Magnetite powder 5.0
Oyster powder 10.0
EXAMPLE 3 preparation of sleep-aid foot paste (III)
A sleep-aiding foot patch was prepared in the same manner as in example 1, except that the formulation shown in table 4 was used:
TABLE 4
Name of raw materials Dosage (kg)
Chinese medicine extract powder for helping sleep 30.0
Far infrared ceramic powder 10.0
Lavender essential oil 0.3
Bamboo vinegar powder 30
Magnetite powder 19.7
Oyster powder 2.0
EXAMPLE 4 preparation of sleep-aid foot paste (IV)
A sleep-aiding foot patch was prepared in the same manner as in example 1, except that the formulation shown in table 5 was used:
TABLE 5
Name of raw materials Dosage (kg)
Chinese medicine extract powder for helping sleep 60.0
Far infrared ceramic powder 15.0
Lavender essential oil 0.1
Bamboo vinegar powder 5.0
Magnetite powder 14.9
Oyster powder 3.0
Comparative example 1
A sleep-aiding foot patch was prepared in the same manner as in example 1, except that the formulation shown in table 6 was used:
TABLE 6
Name of raw materials Dosage (kg)
Chinese medicine extract powder for helping sleep 50.0
Maltodextrin 4.5
Far infrared potteryPorcelain powder 0.0
Lavender essential oil 0.5
Bamboo vinegar powder 10.0
Magnetite powder 15.0
Oyster powder 5.0
Comparative example 2
A sleep-aiding foot patch was prepared in the same manner as in example 1, except that the formulation shown in table 7 was used:
TABLE 7
Name of raw materials Dosage (kg)
Chinese medicine extract powder for helping sleep 50.0
Maltodextrin 15.0
Far infrared ceramic powder 4.5
Lavender essential oil 0.5
Bamboo vinegar powder 10.0
Magnetite powder 0.0
Oyster powder 5.0
Comparative example 3
A sleep-aiding foot patch was prepared in the same manner as in example 1, except that the formulation shown in table 8 was used:
TABLE 8
Name of raw materials Dosage (kg)
Chinese medicine extract powder for helping sleep 50.0
Maltodextrin 5.0
Far infrared ceramic powder 4.5
Lavender essential oil 0.5
Bamboo vinegar powder 10.0
Magnetite powder 15.0
Oyster powder 0.0
Comparative example 4
A sleep-aiding foot patch was prepared in the same manner as in example 1, except that the formulation shown in table 9 was used:
TABLE 9
Name of raw materials Dosage (kg)
Chinese medicine extract powder for helping sleep 0
Maltodextrin 50.0
Far infrared ceramic powder 4.5
Lavender essential oil 0.5
Bamboo vinegar powder 10.0
Magnetite powder 15.0
Oyster powder 5.0
Experimental example 1 Performance evaluation experiment
The foot patch products of examples 1 to 4 and comparative examples 1 to 4 were subjected to sleep-aid performance evaluation experiments, wherein 20 persons in each group were selected as volunteers under the following conditions: 1. age 18-75 years; 2. patients with insomnia were diagnosed according to the Chinese Classification and diagnosis of mental disorders (third edition, CCMD-3); 3. the disease course standard is as follows: at least 3 times per week for more than one month; PSQI > 7 points; 5. the vital signs are stable, the mind is clear, and certain expression capacity is realized; 6. insomnia due to non-organic lesions. If the conditions are met, the method can be selected.
The test method comprises the following steps: firstly, collecting the information related to the sleep of the testees, and grouping the testees according to the PSQI score. The foot is applied to the sole of the foot before sleeping every night, and the Yongquan acupoint is covered with adhesive tape, and removed the next morning before getting up, and the residual medicinal liquid is wiped off with wet towel. After six weeks of treatment for each group, subjects were re-evaluated for sleep effects in Pesburg based on the last month of sleep. Statistical analysis was performed using SPSS 23.0 software. The difference is statistically significant when P < 0.05. The comparative test results are shown in Table 10.
Watch 10
Figure BDA0002567542620000101
From the perspective of sleep treatment improvement effect, the treatment effect of the group in example 1 is the best, and the improvement degree of the sleep quality of comparative examples 1-4, in which no far infrared ceramic powder, magnetite powder, oyster powder or sleep-aiding traditional Chinese medicine extract powder is added in the formula, is not the same as that of the treatment group, so that the statistical significance is achieved.
It should be understood that the above-mentioned embodiments of the present invention are only examples for clearly illustrating the present invention, and are not intended to limit the embodiments of the present invention, and it will be obvious to those skilled in the art that other variations or modifications may be made on the basis of the above description, and all embodiments may not be exhaustive, and all obvious variations or modifications belonging to the technical solutions of the present invention are within the scope of the present invention.

Claims (9)

1. The sleep-aiding foot patch is characterized by comprising a medicine bag consisting of the following components: 30-80 parts by weight of sleep-aiding traditional Chinese medicine extract powder; 0.1-5 parts of lavender essential oil, 1-10 parts of far infrared ceramic powder, 5-40 parts of bamboo vinegar powder, 5-30 parts of magnetite powder and 1-15 parts of oyster powder;
the traditional Chinese medicine extract powder for aiding sleep is prepared from the following raw materials: 5-50 parts of albizia flower, 1-20 parts of ginseng, 10-30 parts of radix rehmanniae, 10-40 parts of white peony root, 10-40 parts of schisandra chinensis, 10-40 parts of polygala tenuifolia, 2-80 parts of spina date seed, 10-40 parts of garden balsam stem, 10-50 parts of oyster and 10-50 parts of magnet.
2. The sleep-aiding foot patch as claimed in claim 1, wherein 35-75 parts by weight of the sleep-aiding traditional Chinese medicine extract powder; 0.1-3 parts of lavender essential oil, 1-10 parts of far infrared ceramic powder, 10-30 parts of bamboo vinegar powder, 2-10 parts of oyster powder and 5-20 parts of magnetite powder.
3. The sleep-aiding foot patch as claimed in claim 2, wherein 45-70 parts by weight of the sleep-aiding traditional Chinese medicine extract powder; 0.1-1 part of lavender essential oil, 1-10 parts of far infrared ceramic powder, 10-30 parts of bamboo vinegar powder, 2-10 parts of oyster powder and 5-20 parts of magnetite powder.
4. The sleep-aiding foot patch as claimed in any one of claims 1 to 3, wherein the sleep-aiding Chinese medicinal extract powder is prepared from the following raw materials: 10-40 parts of albizia flower, 2-10 parts of ginseng, 10-30 parts of radix rehmanniae, 10-30 parts of white peony root, 10-30 parts of schisandra chinensis, 10-30 parts of polygala tenuifolia, 20-70 parts of spina date seed, 10-30 parts of garden balsam stem, 10-30 parts of oyster and 15-45 parts of magnet.
5. The sleep-aiding foot patch as claimed in claim 4, wherein the sleep-aiding traditional Chinese medicine extract powder is prepared from the following raw materials: 20-30 parts of albizia flower, 3-5 parts of ginseng, 15-20 parts of radix rehmanniae, 15-25 parts of white peony root, 15-20 parts of schisandra chinensis, 20-30 parts of polygala tenuifolia, 30-60 parts of spina date seed, 20-30 parts of garden balsam stem, 20-30 parts of oyster and 20-40 parts of magnet.
6. The sleep-aiding foot patch as claimed in any one of claims 1 to 5, wherein the sleep-aiding traditional Chinese medicine extract powder is prepared by mixing the raw material medicines, extracting the raw material medicines with hot water, concentrating the extracted liquid medicine, and drying the concentrated liquid medicine to prepare an extract.
7. The sleep-aiding foot patch as claimed in claim 6, wherein the sleep-aiding traditional Chinese medicine extract powder is prepared by the following method:
I. pulverizing flos Albizziae, Ginseng radix, radix rehmanniae, radix Paeoniae alba, fructus Schisandrae chinensis, cortex et radix Polygalae, semen Ziziphi Spinosae, caulis et folium Gaultheriae Yunnanensis, Concha Ostreae, and Magnetitum powder, and sieving with 40 mesh sieve;
weighing various medicinal powders according to the formula dosage, firstly adding oyster powder and magnetite powder into an extraction tank, adding deionized water with the weight 4-12 times that of the medicaments, heating to 85-100 ℃, keeping the temperature for 0.2-2 hours, then adding other medicinal powders, keeping the temperature for 0.2-2 hours, and then cooling to 40-60 ℃;
filtering dregs, adding deionized water 2-6 times of the weight of the medicine into the dregs, and extracting once according to the time and temperature conditions of the previous step;
and IV, concentrating the liquid medicine extracted twice, drying the liquid medicine into extract, crushing the extract, and sieving the crushed extract by a sieve of 80 meshes.
8. The sleep-aiding foot patch as claimed in claim 1, wherein the particle size of the far infrared ceramic powder, oyster powder and magnet powder is more than 100 meshes.
9. A method of making a sleep aid foot patch package according to any one of claims 1 to 8, comprising: adding the sleep-aiding traditional Chinese medicine extract powder, the lavender essential oil, the far infrared ceramic powder, the bamboo vinegar powder, the oyster powder and the magnetite powder into a mixer according to the proportion, stirring until the mixture is uniformly mixed, and then putting the mixture into a bag made of a heat-seal non-woven fabric material or a heat-seal paper material.
CN202010629245.6A 2020-07-02 2020-07-02 Sleep-aiding foot patch and preparation method thereof Pending CN111840405A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202010629245.6A CN111840405A (en) 2020-07-02 2020-07-02 Sleep-aiding foot patch and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202010629245.6A CN111840405A (en) 2020-07-02 2020-07-02 Sleep-aiding foot patch and preparation method thereof

Publications (1)

Publication Number Publication Date
CN111840405A true CN111840405A (en) 2020-10-30

Family

ID=73152606

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202010629245.6A Pending CN111840405A (en) 2020-07-02 2020-07-02 Sleep-aiding foot patch and preparation method thereof

Country Status (1)

Country Link
CN (1) CN111840405A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112791155A (en) * 2021-01-08 2021-05-14 国珍健康科技(北京)有限公司 Rose foot patch and preparation method thereof
CN112891470A (en) * 2021-01-28 2021-06-04 国珍健康科技(北京)有限公司 Wormwood foot patch and preparation method thereof
CN112972610A (en) * 2021-03-22 2021-06-18 国珍健康科技(北京)有限公司 Evodia rutaecarpa foot patch and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
1993308389: "Q_NSY072-2017薰衣草足贴最新", 《HTTPS://WWW.DOC88.COM/P-3867854324965.HTML》 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112791155A (en) * 2021-01-08 2021-05-14 国珍健康科技(北京)有限公司 Rose foot patch and preparation method thereof
CN112891470A (en) * 2021-01-28 2021-06-04 国珍健康科技(北京)有限公司 Wormwood foot patch and preparation method thereof
CN112972610A (en) * 2021-03-22 2021-06-18 国珍健康科技(北京)有限公司 Evodia rutaecarpa foot patch and preparation method thereof

Similar Documents

Publication Publication Date Title
CN102078520B (en) Chinese medicinal preparation for treating nervous headache and preparation method thereof
CN104305788B (en) A kind of Flos Chrysanthemi Indici mind easing tea health-care medicine pillow and preparation method thereof
CN111110898A (en) Herbal original dew atomized liquid with essence
CN111840405A (en) Sleep-aiding foot patch and preparation method thereof
CN104586669A (en) Fat-reducing externally-applied cream
CN106880782A (en) Disease-relieving and physique enhancing medicine-filled pillow
CN103566202A (en) Traditional Chinese medicine conducive to sleep
CN111150822A (en) Multifunctional herbal essence atomized liquid
CN104666896A (en) Orally-taken medicine for treating alopecia seborrhoeica and preparation method for orally-taken medicine
CN108315185B (en) Health wine for dispelling cold and tonifying kidney and preparation method thereof
CN108126160B (en) Traditional Chinese medicine composition, traditional Chinese medicine health tea, preparation method and application thereof
CN104958429A (en) Traditional Chinese medicinal composition for treating geriatric fracture and preparation method thereof
CN109674704A (en) A kind of Chinese medicine bathing antibacterial liquid/particle improving damp-heat constitution and preparation and application method
CN108355038A (en) The Chinese medicine bathing instant granular of improvement qi deficiency to blood stasis rheumatism and preparation and application method
CN112891470A (en) Wormwood foot patch and preparation method thereof
KR20150122302A (en) Herbal composition, method for producing therof and method for use therof
CN105617330A (en) External essential oil for quickly eliminating skin inflammation
CN105920379A (en) Traditional Chinese medicine eye cream to alleviate pouch and preparation method thereof
CN105919907A (en) Manufacturing method of traditional Chinese medicine eye cream and eye cream
CN105343660A (en) Traditional Chinese medicinal preparation for treating peripheral vertigo and preparation method of traditional Chinese medicinal preparation
CN104906252A (en) Traditional Chinese medicine for treating gray hair
CN104548020A (en) Application of medicine composition in preparing medicine curing senile dementia
CN104083311A (en) Natural plant-derived functional massage lotion
CN112043811A (en) Radix morindae officinalis and radix gastrodiae patch and preparation method thereof
CN112791155A (en) Rose foot patch and preparation method thereof

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20201030

RJ01 Rejection of invention patent application after publication