CN111840151A

CN111840151A - Sunscreen agent

Info

Publication number: CN111840151A
Application number: CN201910353407.5A
Authority: CN
Inventors: 姜婷
Original assignee: Xi'an Bohe Medical Technology Co ltd
Current assignee: Xi'an Bohe Medical Technology Co ltd
Priority date: 2019-04-29
Filing date: 2019-04-29
Publication date: 2020-10-30

Abstract

The invention provides a sunscreen agent, which comprises ethylhexyl methoxycinnamate, bis-ethylhexyloxyphenol methoxyphenyl triazine, diethylamino hydroxybenzoyl hexyl benzoate, octocrine and polygonum aviculare extract. The sunscreen agent can effectively protect ultraviolet rays and infrared rays, and has the effects of calming and relieving the skin.

Description

Sunscreen agent

Technical Field

The invention relates to the field of skin care products, and particularly relates to a sunscreen and application thereof.

Background

Sunlight is an indispensable part of life and includes X-rays, ultraviolet rays, visible rays, infrared rays, and the like. Most of them are blocked by the atmosphere, and if the ecological environment on which people live is further damaged, especially the ozone content of the ozone layer is further reduced, the intensity of ultraviolet rays entering the earth will be increased. When a human is exposed to ultraviolet radiation for a long time and in a large dose, the human can cause great damage to the skin and even the whole body. Because the skin is the outermost organ and tissue of the body, the damage caused by ultraviolet rays is more prominent and obvious.

The ultraviolet ray is a part with the wavelength of 200-400nm in the solar spectrum, accounts for about 6.1 percent in the sunlight, and is divided into 3 sections according to the wavelength: short-band ultraviolet (UVC, 200-. Wherein, the UVC area is called as a sterilization area, the penetration force is weak, the UVC area is almost completely absorbed in the atmosphere, the ground reaching amount is small, the transmission capacity can only reach the horny layer of the skin, and the skin cannot be damaged; UVB has the strongest action on skin, can denature nucleic acid or protein in epidermal cells of the skin, and can cause acute dermatitis, namely sunburn (erythema or burn); UVA can oxidize the reduced melanin in the epidermis to directly tan the skin, has strong penetrating power, slow and lasting effect and accumulative property, can cause skin aging after a long time, and increases the damage of UVB to the skin.

Infrared rays, which are different from photochemical and photo-immunological reactions caused by ultraviolet rays, can cause thermal radiation, and have a penetration force to skin exceeding that of ultraviolet rays, so that skin temperature comes to the market, capillaries dilate congestion, increase water evaporation of skin epidermis, cause adverse effects to skin, and accelerate skin aging.

Therefore, the damage of the skin by the infrared ray cannot be ignored while the damage of the skin by the ultraviolet ray is prevented. With the development of society and the improvement of living standard of people, consumers have higher and higher awareness on skin care, pay more and more attention to skin protection, and have higher and more high requirements on skin care products. The sun protection products in the current market are full of precious and various products with different sun protection indexes, but most of the products are mainly ultraviolet-proof, people do not pay enough attention to the damage of infrared rays to the skin, and even if the damage of the infrared rays is paid enough attention, the sun protection products are not aware of not being protected but needing to be protected. The sun-screening product can protect the skin while preventing the skin from being damaged by ultraviolet rays and infrared rays, and the existing sun-screening product generally only protects the ultraviolet rays, but not the infrared rays and does not pay attention to the sedation and the relaxation of the skin.

Accordingly, in the field of skin care products, there is a strong need for a repair sunscreen product that can protect against both ultraviolet and infrared radiation, and also has a soothing, soothing effect on the skin.

Disclosure of Invention

In view of the above, the present invention provides a sunscreen agent, which has the following characteristics:

the skin care product has good ultraviolet UVA and/or ultraviolet UVB absorption performance and good infrared absorption performance, can promote skin barrier repair, improve the tolerance threshold of the skin, inhibit inflammatory factors, and can maintain the healthy and ruddy skin while protecting ultraviolet rays after long-term use; it also has tranquilizing and soothing effects on skin. On the other hand, the sunscreen effect of the skin care product is further improved by adjusting the weight parts of the components in the sunscreen agent and the composition and proportion of the compound in the sunscreen milk.

Therefore, the invention provides the following technical scheme.

In a first aspect, the present invention provides a sunscreen comprising ethylhexyl methoxycinnamate, bis-ethylhexyloxyphenol methoxyphenyl triazine, hexyl diethylaminohydroxybenzoyl benzoate, octocrylene, and polygonum aviculare extract.

In a preferred embodiment, the weight portion of the ethylhexyl methoxycinnamate is 1-10, the weight portion of bis-ethylhexyloxyphenol methoxyphenyl triazine is 0.5-10, the weight portion of diethylamino hydroxybenzoyl hexyl benzoate is 0.5-10, the weight portion of octocrylene is 0.5-10, and the weight portion of polygonum aviculare extract is 0.1-5.

In a more preferred embodiment, the weight parts of ethylhexyl methoxycinnamate is 1-7, the weight parts of bis-ethylhexyloxyphenol methoxyphenyl triazine is 1-6, the weight parts of diethylamino hydroxybenzoyl hexyl benzoate is 1-6, the weight parts of octocrylene is 1-7, and the weight parts of polygonum aviculare extract is 0.5-4.

In a preferred embodiment, the sunscreen agent further comprises an extract of vitex rotundifolia.

In a preferred embodiment, the part by weight of the vitex rotundifolia fruit extract is 0.1-5.

In a more preferred embodiment, the part by weight of the vitex rotundifolia fruit extract is 0.5-5.

In a second aspect, the present invention provides a sunscreen comprising a sunscreen according to the present invention.

In a preferred embodiment, the sunscreen emulsion further comprises a water retention agent and/or a grease; the water-retaining agent is selected from one or more of glycerol, butanediol and sodium hyaluronate; the grease is selected from one or more of diethylhexyl carbonate, cyclopentadidimethyl siloxane, polydimethylsiloxane, isododecane, cetyl polydimethylsiloxane and isopropyl isostearate.

In a more preferred embodiment, the sunscreen further comprises a skin conditioning agent and/or a pH adjusting agent; the skin conditioning agent is selected from one or more of hydrolyzed yeast protein and purslane extract; the pH adjusting agent may be selected from one or more of phosphate buffer, citrate buffer, acetate buffer, Tris buffer and HEPES buffer.

In a more preferred embodiment, the sunscreen emulsion further comprises a thickener and/or an emulsifier; the thickening agent is selected from one or more of polyacrylate cross-linked polymer-6, xanthan gum, carbomer and hydroxyethyl cellulose; the emulsifier is selected from one or more of abietic acid, behenyl alcohol, glycerol-6 stearate and polyglycerol-6 behenate.

In a more preferred embodiment, the sunscreen milk further comprises a preservative; the preservative is selected from one or more of benzyl alcohol, phenoxyethanol, methyl hydroxybenzoate, benzoic acid, salicylic acid, boric acid, sorbic acid, other alcohols and aldehydes.

In a most preferred embodiment, the sunscreen further comprises water.

In a most preferred embodiment, the water may be deionized water.

In a third aspect, the present invention provides a skin care product comprising the sunscreen agent of the present invention or the sunscreen emulsion of the present invention.

In a fourth aspect, the invention also provides the use of the sunscreen agent or the sunscreen emulsion in the invention in the preparation of skin care products.

In a fifth aspect, the present invention provides a method for preparing a sun-screen, wherein the method comprises the following steps:

(1) uniformly mixing a thickening agent, a water-retaining agent and water, heating, and keeping the temperature until the thickening agent, the water-retaining agent and the water are completely dissolved to obtain a mixture A;

(2) mixing oil and emulsifier uniformly, heating, and keeping the temperature to obtain oil phase B;

(3) uniformly mixing ethylhexyl methoxycinnamate, bis-ethylhexyloxyphenol methoxyphenyl triazine, diethyl amino hydroxybenzoyl hexyl benzoate and octocrylene, heating, and keeping the temperature to obtain an oil phase C;

(4) uniformly mixing the mixture A, the oil phase B and the oil phase C, homogenizing and emulsifying, and vacuumizing and defoaming to obtain a mixture D; (5) cooling the mixture D to 40-45 deg.C, mixing with herba Polygoni Avicularis (Polygonum AVICULARE) extract, fructus Vitics Simplicifoliae (Vitextrifolia) extract, skin conditioner, antiseptic and pH regulator, cooling, and discharging to obtain the sunscreen emulsion.

The thickener may be selected from one or more of polyacrylate crosspolymer-6, xanthan gum, carbomer, and hydroxyethyl cellulose.

The water retaining agent may be selected from one or more of glycerin, butylene glycol and sodium hyaluronate.

The oil may be selected from one or more of diethylhexyl carbonate, cyclopentadimethylsiloxane, polydimethylsiloxane, isododecane, cetyl polydimethylsiloxane and isopropyl isostearate.

The emulsifier can be one or more selected from abietic acid, behenic acid, glycerol-6 stearate and polyglycerol-6 behenate.

The skin conditioning agent may be selected from one or more of hydrolyzed yeast protein, purslane extract.

The pH adjusting agent may be selected from one or more of phosphate buffer, citrate buffer, acetate buffer, Tris buffer and HEPES buffer.

The preservative may be selected from one or more of benzyl alcohol, phenoxyethanol, methylparaben, benzoic acid, salicylic acid, boric acid, sorbic acid, other alcohols and aldehydes.

In a preferred embodiment, the heating temperature in the steps (1) to (3) is 75 to 85 ℃, more preferably 80 ℃.

In a preferred embodiment, the holding time in the steps (2) and (3) is 20-30min, and more preferably 25 min.

In a preferred embodiment, the temperature for the homogeneous emulsification in step (4) is 75-80 ℃, more preferably 78 ℃.

In a preferred embodiment, the time for homogenizing and emulsifying in the step (4) is 10-40min, and more preferably 15 min.

In a preferred embodiment, the cooling temperature in step (5) is 40-45 ℃, more preferably 40 ℃.

Compared with the prior art, the invention has the beneficial effects that:

according to the sunscreen agent provided by the invention, ethylhexyl methoxycinnamate and octocrylene used in the sunscreen agent have good UVB ultraviolet absorption performance; the used diethyl amino hydroxy benzoyl benzoic acid hexyl ester has good UVA ultraviolet absorption performance; the bis-ethylhexyloxyphenol methoxyphenyl triazine has good UVA and UVB ultraviolet absorption performance; the polygonum aviculare extract and the vitex rotundifolia fruit extract have good infrared ray absorption performance; can be widely applied to the field of skin care products.

The sunscreen emulsion provided by the invention contains the sunscreen agent, has good UVA and/or UVB ultraviolet absorption performance and good infrared absorption performance, can improve the sunscreen effect from three aspects of resisting UVB, UVA and infrared and can prevent skin photoaging; the skin conditioner used in the sunscreen milk can promote skin barrier repair, reduce skin redness and swelling, improve skin tolerance threshold, inhibit inflammatory factors, calm and relieve skin, so that the skin is healthier and ruddy; can be widely applied to the field of skin care products.

The sun block provided by the invention is weak in acidity, the pH value is stabilized between 5.5 and 6.5, the sun block is consistent with the average pH value of normal skin, the sun block has good skin affinity, does not stimulate the skin, enables the acid-base balance of the skin, is suitable for any skin and is suitable for long-term use; meanwhile, the sunscreen emulsion provided by the invention can keep excellent stability and glossiness under the storage condition from low temperature (about minus 18 ℃) to high temperature (45 ℃), and has no layering or precipitation phenomenon.

On the other hand, the sunscreen effect of the skin care product is further improved by adjusting the weight parts of the components in the sunscreen agent and the composition and proportion of the compound in the sunscreen milk.

The preparation method of the sunscreen lotion provided by the invention is simple to operate, easy for industrial production, low in cost and high in application value.

Detailed Description

At present, sunscreen products for skin care have the problems of incapability of protecting infrared rays or poor infrared ray protecting effect and skin allergy, and the sunscreen effects of the skin care products are affected. In order to improve the protection effect of the skin care product on ultraviolet rays and infrared rays and calm and relieve the skin so as to enable the sun protection effect of the skin care product to be more ideal, the invention tries to select and adjust the type and the dosage of the protection ultraviolet rays or the infrared rays and select a buffer system matched with the protection ultraviolet rays or the infrared rays, but most of the selection and adjustment modes do not obtain the more ideal effect.

In the process of a great deal of experimental research, the inventor unexpectedly discovers that the combination mode of 'specific sunscreen components and proportions thereof' has the effects of calming and relieving the skin while improving the protection effect of ultraviolet rays and infrared rays, and obtains more ideal sunscreen effect.

Accordingly, the invention provides a sunscreen agent, a sunscreen lotion and a skin care product containing the sunscreen agent and the sunscreen lotion, which overcome the defects of poor ultraviolet and infrared protection effects and skin allergy of the existing skin care products, and achieve an unexpected sunscreen effect.

The present invention will be described in detail below with reference to specific embodiments and examples, and the advantages and various effects of the present invention will be more clearly apparent therefrom. It will be understood by those skilled in the art that these specific embodiments and examples are for the purpose of illustrating the invention and are not to be construed as limiting the invention.

Throughout the specification, unless otherwise specifically noted, terms used herein should be understood as having meanings as commonly used in the art. Thus, unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. If there is a conflict, the present specification will control.

Sunscreen agent

In the present invention, a sunscreen agent is a substance that prevents ultraviolet rays and infrared rays from being irradiated.

As the kind of the substance in the sunscreen agent, there may be mentioned substances containing ethylhexyl methoxycinnamate, bis-ethylhexyloxyphenol methoxyphenyl triazine, diethylamino hydroxybenzoyl hexyl benzoate, octocrylene and polygonum aviculare extract.

For the amount of the substances in the sunscreen, the weight portion of the ethylhexyl methoxycinnamate can be 1-10, the weight portion of the bis-ethylhexyloxyphenol methoxyphenyl triazine can be 0.5-10, the weight portion of the diethylamino hydroxybenzoyl hexyl benzoate can be 0.5-10, the weight portion of the octocrylene can be 0.5-10, and the weight portion of the polygonum aviculare extract can be 0.1-5.

Preferably, for the amount of the substances in the sunscreen agent, the weight part of the ethylhexyl methoxycinnamate can be 1-7, the weight part of the bis-ethylhexyloxyphenol methoxyphenyl triazine can be 1-6, the weight part of the diethylamino hydroxybenzoyl hexyl benzoate can be 1-6, the weight part of the octocrylene can be 1-7, and the weight part of the polygonum aviculare extract can be 0.5-4.

As the kind of the substance in the sunscreen agent, there may be mentioned a substance containing ethylhexyl methoxycinnamate, bis-ethylhexyloxyphenol methoxyphenyl triazine, diethylamino hydroxybenzoyl hexyl benzoate, octocrine, polygonum aviculare extract and vitex rotundifolia fruit extract.

For the amount of the substances in the sunscreen agent, the weight portion of the ethylhexyl methoxycinnamate can be 1-10, the weight portion of the bis-ethylhexyloxyphenol methoxyphenyl triazine can be 0.5-10, the weight portion of the diethylamino hydroxybenzoyl hexyl benzoate can be 0.5-10, the weight portion of the octocrine can be 0.5-10, the weight portion of the polygonum aviculare extract can be 0.1-5, and the weight portion of the fructus viticis extract can be 0.1-5.

Preferably, for the amount of the substances in the sunscreen agent, the weight part of the ethylhexyl methoxycinnamate can be 1-7, the weight part of the bis-ethylhexyloxyphenol methoxyphenyl triazine can be 1-6, the weight part of the diethylamino hydroxybenzoyl hexyl benzoate can be 1-6, the weight part of octocrine can be 1-7, the weight part of the polygonum aviculare extract can be 0.5-4, and the weight part of the fructus viticis extract can be 0.5-5.

For example, when the weight portion of ethylhexyl methoxycinnamate is controlled to be 1-10, the weight portion of bis-ethylhexyloxyphenol methoxyphenyl triazine is controlled to be 0.5-10, the weight portion of diethylamino hydroxybenzoyl hexyl benzoate is controlled to be 0.5-10, the weight portion of octocrilene is controlled to be 0.5-10, the weight portion of polygonum aviculare extract is controlled to be 0.1-5, and the weight portion of fructus viticis extract is controlled to be 0.1-5, the composition can effectively protect ultraviolet rays and infrared rays and calm and relieve the skin. The weight portion of ethylhexyl oxy-cinnamate is controlled to be 1-7, the weight portion of bis-ethylhexyloxyphenol methoxyphenyl triazine is controlled to be 1-6, the weight portion of diethylamino hydroxybenzoyl hexyl benzoate is controlled to be 1-6, the weight portion of octocrine is controlled to be 1-7, the weight portion of polygonum aviculare extract is controlled to be 0.5-4, and the weight portion of fructus viticis extract is controlled to be 0.5-5, so that the skin can be well and fully protected from ultraviolet rays and infrared rays and calmed and relieved.

Oil and fat

In the present invention, the oil-and-fat-based raw material mainly includes oil and wax, which are a generic name of oil-phase raw materials, which are also a base material, oil which is in a fluid form at normal temperature, and wax which is in a semisolid form, and the main components of which are higher fatty acid esters. Mainly has the functions of skin care, lubrication, solidification and shaping and the like.

Depending on the source, oily materials can be broadly classified into animal fats and oils, vegetable fats and oils, mineral fats and oils, semisynthetic fats and oils, and related waxes. Generally, the skin absorbs animal oils best, followed by vegetable oils.

For the type of grease, the present invention is selected from one or more of diethylhexyl carbonate, cyclopentadimethylsiloxane, polydimethylsiloxane, isododecane, cetyl polydimethylsiloxane, and isopropyl isostearate.

The amount of the oil or fat to be used may be selected by those skilled in the art depending on the kind of the oil or fat, and for example, 0.1 to 4 parts by weight may be used when diethylhexyl carbonate is used, 0.1 to 5 parts by weight may be used when cyclopentadimethicone is used, 0.1 to 5 parts by weight may be used when dimethicone is used, 0.1 to 5 parts by weight may be used when isododecane is used, 0.1 to 3 parts by weight may be used when cetyl dimethicone is used, and 0.1 to 3 parts by weight may be used when isopropyl isostearate is used.

Skin conditioning agent

In the present invention, the skin conditioner means an agent which can improve the appearance of dry/damaged skin, reduce peeling and restore skin softness, and also has anti-irritation, anti-inflammatory and skin-soothing effects.

For the class of skin conditioners, the present invention is selected from one or more of hydrolyzed yeast protein, purslane extract.

The amount of skin conditioning agent used can be selected by one skilled in the art depending on the type of skin conditioning agent, for example, 0.1 to 5 parts by weight when hydrolyzed yeast protein is used, and 0.1 to 5 parts by weight when purslane extract is used.

pH regulator

In the present invention, the pH regulator refers to a reagent capable of offsetting and reducing the influence of an external strong acid or strong base on the pH of a solution to a certain extent, thereby keeping the pH of the solution relatively stable.

For the kind of the pH adjusting agent, the present invention is selected from one or more of phosphate buffer, citrate buffer, acetate buffer, Tris buffer, and HEPES buffer.

The amount of the pH adjustor can be selected by those skilled in the art according to the kind of the pH adjustor, and for example, 0.001 to 0.5 parts by weight can be used when a citric acid buffer is used.

Emulsifier

In the present invention, the emulsifier is a substance capable of improving the surface tension between various constituent phases in an emulsion to form a uniform and stable dispersion or emulsion. Emulsifiers are surface-active substances which have both hydrophilic and lipophilic groups in the molecule and which accumulate at the oil/water interface and reduce the interfacial tension and the energy required to form an emulsion, thereby increasing the energy of the emulsion.

As for the kind of the emulsifier, the present invention is selected from one or more of abietic acid, behenic acid, glycerol-6 stearate and polyglyceryl-6 behenate.

As the amount of the emulsifier to be used, those skilled in the art can select the amount according to the kind of the emulsifier.

Thickening agent

Thickeners can have a significant effect on the appearance of the product. The thickener enables the system to achieve the thickening purpose through a rod-shaped micelle formed by the thickener and a surfactant, a three-dimensional hydration network structure formed by the action of the thickener and water, a self macromolecular long-chain structure and the like.

For the kind of the thickener, the present invention is selected from one or more of polyacrylate crosspolymer-6, xanthan gum, carbomer, and hydroxyethylcellulose.

The amount of the thickener used can be selected by those skilled in the art according to the type of the thickener, and for example, 0.5 parts by weight or less can be used when triton 100 is used, 0.5 parts by weight or less can be used when xanthan gum is used, 0.5 parts by weight or less can be used when carbomer is used, and 0.3 parts by weight or less can be used when hydroxyethyl cellulose is used.

Water-retaining agent

In the invention, the water-retaining agent is a reagent which can protect skin, keep the skin moist, smooth, fine, tender and elastic.

For the kind of the water retention agent, the present invention is selected from one or more of glycerin, butylene glycol and sodium hyaluronate.

The amount of the water retaining agent to be used is selected by those skilled in the art depending on the kind of the water retaining agent, and for example, 1 to 10 parts by weight may be used when glycerin is used, 1 to 5 parts by weight may be used when butylene glycol is used, and 0.1 to 0.5 parts by weight may be used when sodium hyaluronate is used.

Preservative

In the present invention, the preservative is a substance added to the skin care product for the purpose of inhibiting the growth and proliferation of microorganisms in the skin care product, and is used to prolong the shelf life of the skin care product.

Skin care preservatives come in different categories. Common skin care product preservatives include benzyl alcohol, phenoxyethanol, methylparaben, benzoic acid, salicylic acid, boric acid, sorbic acid, other alcohols, aldehydes and the like.

The amount of the preservative to be used can be selected by those skilled in the art depending on the kind of the preservative, and for example, 0.2 to 0.5 parts by weight can be used when phenoxyethanol is used.

Skin care product

The skin care products of the present invention may include containers, instructions for use, use aids, and/or other structures and/or reagents as desired for performing the performance test.

Other structures necessary for performing performance tests in the skin care products of the present invention include, but are not limited to, structures for sampling, structures for performing control, and/or structures for observing the progress or results of the assay.

The other agents required for performance testing in the skin care products of the present invention include, but are not limited to, culture media, detergents, color developers and/or terminators, and other sunscreens besides the sunscreens, water retention agents, thickeners, oils, emulsifiers, skin conditioners, pH adjusters, preservatives of the present invention, water retention agents, thickeners, oils, emulsifiers, skin conditioners, pH adjusters, preservatives.

The present invention will be described in more detail below with reference to examples, but the present invention is not limited to these examples.

Example 1: preparation of sunscreen emulsion

Example 1 provides a sunscreen emulsion comprising the following components in parts by weight:

5 parts of ethylhexyl methoxycinnamate, 2 parts of bis-ethylhexyloxyphenol methoxyphenyl triazine, 2.5 parts of diethyl hydroxy benzoyl benzoate, 3 parts of octocrylene, 4 parts of polygonum aviculare extract, 5 parts of fructus viticis extract, 3 parts of diethylhexyl carbonate, 5 parts of cyclopenta dimethyl siloxane, 4 parts of dimethyl polysiloxane, 5 parts of isododecane, 1.5 parts of cetyl dimethyl polysiloxane, 3 parts of isopropyl isostearate, 2 parts of polyglycerol-6 stearate and 2 parts of polyglycerol-6 behenate, 60.4 parts of polyacrylate cross-linked polymer, 0.4 part of xanthan gum, 0.1 part of carbomer, 0.2 part of hydroxyethyl cellulose, 7.5 parts of glycerol, 4 parts of butanediol, 0.3 part of sodium hyaluronate, 2.5 parts of hydrolyzed yeast protein, 3 parts of purslane extract, 0.2 part of phenoxyethanol, 0.1 part of methylparaben, 0.002 part of citric acid and a proper amount of deionized water.

The preparation of the sunscreen of example 1 is as follows:

(1) adding 0.4 part by weight of polyacrylate cross-linked polymer-6, 0.4 part by weight of xanthan gum, 0.1 part by weight of carbomer, 0.2 part by weight of hydroxyethyl cellulose, 7.5 parts by weight of glycerol, 4 parts by weight of butanediol, 0.3 part by weight of sodium hyaluronate and a proper amount of deionized water into a water phase pot, uniformly mixing, heating to 80 ℃, and keeping the temperature for 25min until complete dissolution to obtain a mixture A;

(2) Adding 3 parts by weight of diethylhexyl carbonate, 5 parts by weight of cyclopentadimethylsiloxane, 4 parts by weight of polydimethylsiloxane, 5 parts by weight of isododecane, 1.5 parts by weight of cetyl polydimethylsiloxane, 3 parts by weight of isopropyl isostearate, 2 parts by weight of polyglycerol-6 stearate and 2 parts by weight of polyglycerol-6 behenate into an oil phase pot, uniformly mixing, heating to 80 ℃, and keeping the temperature for 25min to obtain an oil phase B;

(3) adding 5 parts by weight of ethylhexyl methoxycinnamate, 2 parts by weight of bis-ethylhexyloxyphenol methoxyphenyl triazine, 2.5 parts by weight of diethyl amino hydroxybenzoyl hexyl benzoate and 3 parts by weight of octocrylene into a stainless steel container, uniformly mixing, heating to 80 ℃, and preserving heat for 25min to obtain an oil phase C;

(4) uniformly mixing the mixture A, the oil phase B and the oil phase C in an emulsifying pot, homogenizing and emulsifying at 78 ℃ for 15min, and vacuumizing and defoaming to obtain a mixture D;

(5) and cooling the mixture D to 40 ℃, adding 4 parts by weight of polygonum aviculare extract, 5 parts by weight of fructus viticis extract, 2.5 parts by weight of hydrolyzed yeast protein, 3 parts by weight of purslane extract, 0.2 parts by weight of phenoxyethanol, 0.1 parts by weight of methylparaben and 0.002 parts by weight of citric acid, uniformly mixing, cooling at 40 ℃, and discharging to obtain the sunscreen emulsion.

Example 2: preparation of sunscreen emulsion

Example 2 provides a sunscreen emulsion comprising the following components in parts by weight:

5 parts of ethylhexyl methoxycinnamate, 2.5 parts of diethyl-amino-hydroxybenzoyl hexyl benzoate, 3 parts of octocrine, 4 parts of polygonum aviculare extract, 5 parts of fructus viticis extract, 3 parts of diethylhexyl carbonate, 5 parts of cyclopenta dimethyl siloxane, 4 parts of dimethyl siloxane, 5 parts of isododecane, 1.5 parts of cetyl dimethyl siloxane, 3 parts of isopropyl isostearate, 2 parts of polyglycerol-6 stearate, 2 parts of polyglycerol-6 behenate, 60.4 parts of polyacrylate cross-linked polymer, 0.4 part of xanthan gum, 0.1 part of carbomer, 0.2 part of hydroxyethyl cellulose, 7.5 parts of glycerol, 4 parts of butanediol, 0.3 part of sodium hyaluronate, 2.5 parts of hydrolyzed yeast protein, 3 parts of purslane extract, 0.2 part of phenoxyethanol, 0.1 part of methyl hydroxybenzoate, 0.002 part of citric acid and a proper amount of deionized water.

The preparation of the sunscreen of example 2 is as follows:

(3) adding 5 parts by weight of ethylhexyl methoxycinnamate, 2.5 parts by weight of diethylamino hydroxybenzoyl hexyl benzoate and 3 parts by weight of octocrylene into a stainless steel container, uniformly mixing, heating to 80 ℃, and keeping the temperature for 25min to obtain an oil phase C;

Example 3: preparation of sunscreen emulsion

Example 3 provides a sunscreen emulsion comprising the following components in parts by weight:

5 parts of ethylhexyl methoxycinnamate, 3 parts of octocrylene, 4 parts of polygonum aviculare extract, 5 parts of fructus viticis extract, 3 parts of diethylhexyl carbonate, 5 parts of cyclopentadimethylsiloxane, 4 parts of polydimethylsiloxane, 5 parts of isododecane, 1.5 parts of cetyl polydimethylsiloxane, 3 parts of isopropyl isostearate, 2 parts of polyglycerol-6 stearate, 2 parts of polyglycerol-6 behenate, 60.4 parts of polyacrylate cross-linked polymer, 0.4 part of xanthan gum, 0.1 part of carbomer, 0.2 part of hydroxyethyl cellulose, 7.5 parts of glycerol, 4 parts of butanediol, 0.3 part of sodium hyaluronate, 3 parts of purslane extract, 0.2 part of phenoxyethanol, 0.1 part of methylparaben, 0.002 part of citric acid and a proper amount of deionized water.

The preparation of the sunscreen of example 3 is as follows:

(3) adding 5 parts by weight of ethylhexyl methoxycinnamate and 3 parts by weight of octocrylene into a stainless steel container, uniformly mixing, heating to 80 ℃, and preserving heat for 25min to obtain an oil phase C;

(5) and cooling the mixture D to 40 ℃, adding 4 parts by weight of polygonum aviculare extract, 5 parts by weight of fructus viticis extract, 3 parts by weight of purslane extract, 0.2 part by weight of phenoxyethanol, 0.1 part by weight of methylparaben and 0.002 part by weight of citric acid, uniformly mixing, cooling at 40 ℃, and discharging to obtain the sunscreen emulsion.

Example 4: preparation of sunscreen emulsion

Example 4 provides a sunscreen emulsion comprising the following components in parts by weight:

5 parts of ethylhexyl methoxycinnamate, 4 parts of polygonum aviculare extract, 5 parts of fructus viticis extract, 3 parts of diethylhexyl carbonate, 5 parts of cyclopenta dimethyl siloxane, 4 parts of dimethyl siloxane, 5 parts of isododecane, 1.5 parts of cetyl dimethyl siloxane, 3 parts of isopropyl isostearate, 2 parts of polyglycerol-6 stearate, 2 parts of polyglycerol-6 behenate, 60.4 parts of polyacrylate cross-linked polymer, 0.4 part of xanthan gum, 0.1 part of carbomer, 0.2 part of hydroxyethyl cellulose, 7.5 parts of glycerol, 4 parts of butanediol, 0.3 part of sodium hyaluronate, 2.5 parts of hydrolyzed yeast protein, 0.2 part of phenoxyethanol, 0.1 part of methylparaben, 0.002 part of citric acid and a proper amount of deionized water.

The preparation of the sunscreen of example 4 is as follows:

(3) adding 5 parts by weight of ethylhexyl methoxycinnamate into a stainless steel container, uniformly mixing, heating to 80 ℃, and keeping the temperature for 25min to obtain an oil phase C;

(5) and cooling the mixture D to 40 ℃, adding 4 parts by weight of polygonum aviculare extract, 5 parts by weight of fructus viticis extract, 2.5 parts by weight of hydrolyzed yeast protein, 0.2 parts by weight of phenoxyethanol, 0.1 parts by weight of methylparaben and 0.002 parts by weight of citric acid, uniformly mixing, cooling at 40 ℃, and discharging to obtain the sunscreen emulsion.

Example 5: preparation of sunscreen emulsion

Example 5 provides a sunscreen emulsion comprising the following components in parts by weight:

5 parts of ethylhexyl methoxycinnamate, 5 parts of fructus viticis extract, 3 parts of diethylhexyl carbonate, 5 parts of cyclopenta dimethyl silicone polymer, 4 parts of dimethyl silicone polymer, 5 parts of isododecane, 1.5 parts of cetyl dimethyl silicone polymer, 3 parts of isopropyl isostearate, 2 parts of polyglycerol-6 stearate, 2 parts of polyglycerol-6 behenate, 60.4 parts of polyacrylate cross-linked polymer, 0.4 part of xanthan gum, 0.1 part of carbomer, 0.2 part of hydroxyethyl cellulose, 7.5 parts of glycerol, 4 parts of butanediol, 0.3 part of sodium hyaluronate, 0.2 part of phenoxyethanol, 0.1 part of methylparaben, 0.002 part of citric acid and a proper amount of deionized water.

The preparation of the sunscreen of example 5 is as follows:

(5) and cooling the mixture D to 40 ℃, adding 5 parts by weight of fructus viticis extract, 0.2 parts by weight of phenoxyethanol, 0.1 parts by weight of methylparaben and 0.002 parts by weight of citric acid, uniformly mixing, cooling at 40 ℃, and discharging to obtain the sunscreen emulsion.

Example 6: preparation of sunscreen emulsion

Example 6 provides a sunscreen emulsion comprising the following components in parts by weight:

1 part of ethylhexyl methoxycinnamate, 0.5 part of bis-ethylhexyloxyphenol methoxyphenyl triazine, 0.5 part of diethyl aminohydroxybenzoyl hexyl benzoate, 0.5 part of octocrylene, 0.1 part of polygonum aviculare extract, 3 parts of diethylhexyl carbonate, 2 parts of polyglycerol-6 stearate, 60.4 parts of polyacrylate cross-linked polymer, 7.5 parts of glycerol, 3 parts of purslane extract, 0.2 part of phenoxyethanol, 0.002 part of citric acid and a proper amount of deionized water.

The preparation of the sunscreen of example 6 is as follows:

(1) adding 0.4 part by weight of polyacrylate cross-linked polymer-6, 7.5 parts by weight of glycerol and a proper amount of deionized water into a water phase pot, uniformly mixing, heating to 80 ℃, and keeping the temperature for 25min until the mixture is completely dissolved to obtain a mixture A;

(2) adding 3 parts by weight of diethylhexyl carbonate and 2 parts by weight of polyglycerol-6 stearate into an oil phase pot, uniformly mixing, heating to 80 ℃, and preserving heat for 25min to obtain an oil phase B;

(3) adding 1 weight part of ethylhexyl methoxycinnamate, 0.5 weight part of bis-ethylhexyloxyphenol methoxyphenyl triazine, 0.5 weight part of diethylamino hydroxybenzoyl hexyl benzoate and 0.5 weight part of octocrylene into a stainless steel container, uniformly mixing, heating to 80 ℃, and preserving heat for 25min to obtain an oil phase C;

(5) and cooling the mixture D to 40 ℃, adding 0.1 part by weight of polygonum aviculare extract, 3 parts by weight of purslane extract, 0.2 part by weight of phenoxyethanol and 0.002 part by weight of citric acid, uniformly mixing, cooling at 40 ℃, and discharging to obtain the sunscreen emulsion.

Example 7: preparation of sunscreen emulsion

Example 7 provides a sunscreen emulsion comprising the following components in parts by weight:

10 parts of ethylhexyl methoxycinnamate, 10 parts of bis-ethylhexyloxyphenol methoxyphenyl triazine, 10 parts of diethyl amino hydroxybenzoyl hexyl benzoate, 10 parts of octocrylene, 5 parts of polygonum aviculare extract, 3 parts of diethylhexyl carbonate, 2 parts of polyglycerol-6 stearate, 60.4 parts of polyacrylate cross-linked polymer, 7.5 parts of glycerol, 3 parts of purslane extract, 0.2 part of phenoxyethanol, 0.002 part of citric acid and a proper amount of deionized water.

The sunscreen of example 7 was prepared as follows:

(3) adding 10 parts by weight of ethylhexyl methoxycinnamate, 10 parts by weight of bis-ethylhexyloxyphenol methoxyphenyl triazine, 10 parts by weight of diethyl amino hydroxybenzoyl hexyl benzoate and 10 parts by weight of octocrylene into a stainless steel container, uniformly mixing, heating to 80 ℃, and preserving heat for 25min to obtain an oil phase C;

(5) and cooling the mixture D to 40 ℃, adding 5 parts by weight of polygonum aviculare extract, 3 parts by weight of purslane extract, 0.2 part by weight of phenoxyethanol and 0.002 part by weight of citric acid, uniformly mixing, cooling at 40 ℃, and discharging to obtain the sunscreen emulsion.

Comparative example: preparation of sunscreen emulsion

To demonstrate that a sunscreen outside the weight part range of the present invention does not have the sunscreen effect of the present invention as compared to a sunscreen within the weight part range of the present invention, a comparative example is provided which differs from example 6 in that: the weight portion of ethylhexyl methoxycinnamate in the sunscreen milk is 0.5, the weight portion of bis-ethylhexyloxyphenol methoxyphenyl triazine is 0.3, the weight portion of diethyl amino hydroxybenzoyl hexyl benzoate is 0.3, the weight portion of octocrine is 0.3, and the weight portion of polygonum aviculare extract is 0.05.

The comparative example provides a sunscreen emulsion comprising the following components in parts by weight:

0.5 part of ethylhexyl methoxycinnamate, 0.3 part of bis-ethylhexyloxyphenol methoxyphenyl triazine, 0.3 part of diethyl aminooxybenzoyl hexyl benzoate, 0.3 part of octocrylene, 0.05 part of polygonum aviculare extract, 3 parts of diethylhexyl carbonate, 2 parts of polyglycerol-6 stearate, 60.4 parts of polyacrylate cross-linked polymer, 7.5 parts of glycerol, 3 parts of purslane extract, 0.2 part of phenoxyethanol, 0.002 part of citric acid and a proper amount of deionized water.

The preparation of the sunscreen of the comparative example was as follows:

(3) adding 0.5 weight part of ethylhexyl methoxycinnamate, 0.3 weight part of bis-ethylhexyloxyphenol methoxyphenyl triazine, 0.3 weight part of diethylamino hydroxybenzoyl hexyl benzoate and 0.3 weight part of octocrylene into a stainless steel container, uniformly mixing, heating to 80 ℃, and preserving heat for 25min to obtain an oil phase C;

(5) and cooling the mixture D to 40 ℃, adding 0.05 part by weight of polygonum aviculare extract, 3 parts by weight of purslane extract, 0.2 part by weight of phenoxyethanol and 0.002 part by weight of citric acid, uniformly mixing, cooling at 40 ℃, and discharging to obtain the sunscreen emulsion.

Example 8: skin care, sun protection performance testing of sun protection lotions

The Melanin (Melanin) value and Erythema (erythma) value data of the invention are purchased from Beijing Dynasty Tuoda science and technology Limited company in Denmark

Measured by a skin noninvasive detector. The transepidermal water loss (TEWL) data of the present invention was measured by Derma-ExpertMC 960, a skin diagnosis expert from CK, Germany.

30 healthy volunteers 25-30 years old were tested, and Melanin value and Erythema value of the tested part of the volunteer before using the sunscreen lotion of the present invention were recorded, and then the sunscreen lotions of examples 1-8 were continuously applied to the face of the volunteer at a position of 10mm cheek by 10mm²The skin area is 10 × 10mm selected from symmetrical part of face of the same person²Area of skin, without any skin care product, applied each morning and evening for 4 weeks, and after 4 weeks the Melanin value, the erythma value, and The data before trial use were compared, and eight sets of data were selected, wherein trial examples 1-7, comparative example, and the data are shown in table 9 below. The Melanin value is a skin Melanin value which can indicate whether the skin is suntanned or not, and the Melanin value is not increased after the skin is used, so that the product has a sun-block black effect and the skin is not suntanned; the Erythema value is the Erythema value of the skin, namely the sunburn value, and indicates whether the skin is sunburned or not, and the Erythema value is not increased after the skin care product is used, so that the skin is not sunburned. The two data are combined to show the sun-screening effect of the sun-screening milk; the data in table 9 were measured for five sets of data for each test point and then averaged.

The TWEL value indicates the water loss rate of the epidermis of the skin within a period of time, indirectly indicates the barrier function of the skin, if the TEWL value is reduced, the water dispersion loss of the skin is reduced within a period of time, and the barrier function of the skin is improved, thereby indicating that the invention has repairing effect on the skin. The data in table 9 were measured for five sets of data for each test point and then averaged.

TABLE 9 Melanin, Erythema and TEWL values of sunscreens using different formulation systems

From the above results, it can be seen that:

after the sun block emulsion is used, the melanin value is obviously reduced, which shows that the sun block emulsion has sun block effect and can effectively prevent the skin from being tanned; after the sun block emulsion is used, the erythema value is obviously reduced, which shows that the sun block emulsion can effectively prevent skin from being sunburned; meanwhile, after the sunscreen lotion disclosed by the invention is used, the water loss rate is reduced, the water dispersion loss of the skin is reduced, and the skin barrier function is improved, so that the sunscreen lotion disclosed by the invention has a repairing effect on the skin, and the sunscreen lotion disclosed by the invention achieves a more ideal sunscreen effect.

Whereas, after using a sunscreen outside the present invention (i.e., the comparative example), the melanin value was significantly increased, i.e., the skin was tanned after using the sunscreen of the comparative example; after using the sunscreen of the comparative example, the erythema value also increased, even after sunburn of the skin after using the sunscreen of the comparative example; meanwhile, after the sunscreen lotion of the comparative example is used, the water loss rate is unchanged, and the skin barrier function is not improved, namely, the sunscreen effect of the sunscreen lotion of the comparative example is poor.

It is to be understood that the invention disclosed is not limited to the particular methodology, protocols, and materials described, as these may vary. It is also to be understood that the terminology used herein is for the purpose of describing particular embodiments only, and is not intended to limit the scope of the present invention which will be limited only by the appended claims.

Those skilled in the art will also recognize, or be able to ascertain using no more than routine experimentation, many equivalents to the specific embodiments of the invention described herein. Such equivalents are intended to be encompassed by the following claims.

Claims

1. A sunscreen, wherein the sunscreen comprises ethylhexyl methoxycinnamate, bis-ethylhexyloxyphenol methoxyphenyl triazine, hexyl diethylamino hydroxybenzoyl benzoate, octocrylene, and polygonum aviculare extract.

2. The sunscreen of claim 1, wherein the ethylhexyl methoxycinnamate is in a weight fraction of 1 to 10, the bis-ethylhexyloxyphenol methoxyphenyl triazine is in a weight fraction of 0.5 to 10, the diethylamino hydroxybenzoyl hexyl benzoate is in a weight fraction of 0.5 to 10, the octocrylene is in a weight fraction of 0.5 to 10, and the polygonum aviculare extract is in a weight fraction of 0.1 to 5.

3. The sunscreen of claim 2, wherein the ethylhexyl methoxycinnamate is in a weight fraction of 1-7, bis-ethylhexyloxyphenol methoxyphenyl triazine is in a weight fraction of 1-6, hexyl diethylaminohydroxybenzoyl benzoate is in a weight fraction of 1-6, octocrylene is in a weight fraction of 1-7, and polygonum aviculare extract is in a weight fraction of 0.5-4.

4. The sunscreen of claim 1, wherein the sunscreen further comprises an extract of Vitex agnus-castus.

5. The sunscreen of claim 4, wherein the vitex rotundifolia fruit extract is present in an amount of 0.1-5 parts by weight.

6. The sunscreen of claim 5, wherein the vitex rotundifolia fruit extract is present in an amount of 0.5 to 5 parts by weight.

7. A sunscreen comprising the sunscreen of any one of claims 1-6.

8. The sun block of claim 7, wherein the sun block further comprises a water retention agent and/or an oil

A lipid; the water-retaining agent is selected from one or more of glycerol, butanediol and sodium hyaluronate; the grease is selected from one or more of diethylhexyl carbonate, cyclopentadidimethyl siloxane, polydimethylsiloxane, isododecane, cetyl polydimethylsiloxane and isopropyl isostearate.

9. The sun-protecting cream according to claim 8, wherein said sun-protecting cream further comprises a skin conditioning agent and £ or £ er

Or a pH adjusting agent; the skin conditioning agent is selected from one or more of hydrolyzed yeast protein and purslane extract; the pH regulator is selected from one or more of phosphate buffer, citrate buffer, acetate buffer, Tris buffer and HEPES buffer.

10. The suncare milk of claim 9, wherein the suncare milk further comprises a thickener and/or an emulsifier; the thickening agent is selected from one or more of polyacrylate cross-linked polymer-6, xanthan gum, carbomer and hydroxyethyl cellulose; the emulsifier is selected from one or more of abietic acid, behenyl alcohol, glycerol-6 stearate and polyglycerol-6 behenate.

11. The sun-care lotion according to claim 10, wherein the sun-care lotion further comprises a preservative; the preservative is selected from one or more of benzyl alcohol, phenoxyethanol, methyl hydroxybenzoate, benzoic acid, salicylic acid, boric acid, sorbic acid, other alcohols and aldehydes.

12. A skin care product comprising the sunscreen of any one of claims 1-6 or the sunscreen of any one of claims 7-11.

13. Use of a sunscreen as claimed in any one of claims 1 to 6 or a sunscreen as claimed in any one of claims 7 to 11 in the manufacture of a skin care product.