CN111812340A - Temperature raising disc mechanism of full-automatic urine specific protein analyzer - Google Patents

Temperature raising disc mechanism of full-automatic urine specific protein analyzer Download PDF

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Publication number
CN111812340A
CN111812340A CN202010473037.1A CN202010473037A CN111812340A CN 111812340 A CN111812340 A CN 111812340A CN 202010473037 A CN202010473037 A CN 202010473037A CN 111812340 A CN111812340 A CN 111812340A
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China
Prior art keywords
placing
reaction cup
temperature raising
specific protein
tray
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CN202010473037.1A
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Chinese (zh)
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CN111812340B (en
Inventor
姜文波
王德正
李文
许建成
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Hangzhou Longxin Technology Co ltd
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Hangzhou Longxin Technology Co ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00346Heating or cooling arrangements
    • G01N2035/00356Holding samples at elevated temperature (incubation)
    • G01N2035/00366Several different temperatures used
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00346Heating or cooling arrangements
    • G01N2035/00445Other cooling arrangements

Abstract

The invention provides a temperature raising tray mechanism of a full-automatic urine specific protein analyzer, belongs to the technical field of medical instruments, and aims to solve the problems that in the prior art, a temperature raising tray for incubating samples is not uniformly heated and has large temperature difference, so that analysis and diagnosis results are greatly influenced. This temperature raising plate mechanism of specific protein analyzer of full-automatic urine, including placing the tray, it includes reaction cup portion of placing and sample reagent portion of placing to place the tray, the below of placing the tray is equipped with refrigeration dish and heat preservation part, sample reagent portion of placing, heat preservation part and refrigeration dish enclose into the accommodation space one that is used for holding sample and reagent, reaction cup portion of placing with heat preservation part encloses into the accommodation space two that is used for holding the reaction cup, be equipped with the heater block in the accommodation space two. The invention is used for analyzing specific protein in urine.

Description

Temperature raising disc mechanism of full-automatic urine specific protein analyzer
Technical Field
The invention belongs to the technical field of medical instruments, and particularly relates to a temperature raising disc mechanism of a full-automatic urine specific protein analyzer.
Background
The diagnosis method, in vitro diagnosis, which is the most commonly used method in the medical field at present, refers to collecting body fluid, excrement and secretion of a human body to perform chemical composition or chemical reaction analysis so as to judge human body pathological changes. Such as chemiluminescence analysis and molecular diagnosis. The diagnosis methods adopt automatic or semi-automatic instruments to sample and analyze, and give a diagnosis report.
The immune reaction is sensitive to temperature, and the reliability of the detection result can be ensured only by the detected sample and the reagent under the appropriate temperature environment. However, the incubation tray for incubating the samples in the prior art is not uniformly heated and has a large temperature difference, thereby having a large influence on the analysis and diagnosis results.
Disclosure of Invention
The invention aims to solve the technical problems and provides a temperature raising disc mechanism of a full-automatic urine specific protein analyzer.
In order to achieve the purpose, the invention adopts the following technical scheme:
the temperature raising plate mechanism of the full-automatic urine specific protein analyzer comprises a placing tray, wherein the placing tray comprises a reaction cup placing part and a sample reagent placing part, a refrigerating plate and a heat preservation component are arranged below the placing tray, the sample reagent placing part, the heat preservation component and the refrigerating plate enclose a first accommodating space for accommodating a sample and a reagent, the reaction cup placing part and the heat preservation component enclose a second accommodating space for accommodating a reaction cup, and a heating component is arranged in the second accommodating space.
Preferably, the bottom of the refrigerating disc is provided with a plurality of semiconductor refrigerating pieces, each semiconductor refrigerating piece comprises a cold end and a hot end, and the cold ends of the semiconductor refrigerating pieces are in contact with the refrigerating disc.
Preferably, a radiator is arranged at the hot end of the semiconductor refrigerating sheet and connected with a radiating fan.
Preferably, the placing tray includes a reaction cup holder and a sample reagent holder, the reaction cup placing portion is provided on the reaction cup holder, the sample reagent placing portion is provided on the sample reagent holder, the reaction cup holder is ring-shaped, and the reaction cup holder is fixedly mounted on an edge of the sample reagent holder.
Preferably, the reaction cup holder comprises a plurality of fan-ring-shaped cup holder sheets.
Preferably, a plurality of reaction cup placing holes are uniformly formed in the reaction cup placing portion along the circumferential direction, a plurality of urine collecting tube placing holes and reagent placing holes are uniformly formed in the sample reagent placing portion along the circumferential direction, and the placing tray is connected with a rotating motor.
Preferably, the temperature raising plate mechanism further comprises a temperature raising cover, a placing window and a sampling port are formed in the temperature raising cover, a detection cover plate is arranged at the position of the placing window, and the detection cover plate is rotatably connected with the temperature raising cover.
Preferably, the detection cover plate is provided with a limit baffle.
After the technical scheme is adopted, the invention has the following advantages:
the temperature raising tray mechanism comprises a reaction cup placing part and a sample reagent placing part, wherein the reaction cup placing part and the sample reagent placing part are respectively used for placing reaction cups, samples and reagents which are suitable for different temperatures. The sample reagent placing part, the heat preservation part and the refrigerating disc enclose a first accommodating space for accommodating a sample and a reagent, and the sample and the reagent are refrigerated in the first accommodating space; the reaction cup placing part and the heat preservation part enclose a second accommodating space for accommodating the reaction cup, and the sample cup is kept at the temperature of the human body environment in the second accommodating space. The temperature raising tray mechanism of the invention has uniform heating and small temperature deviation, so that the analysis and diagnosis result is accurate.
Drawings
FIG. 1 is a schematic structural diagram of a temperature raising tray mechanism of a fully automatic urine specific protein analyzer according to the present invention;
FIG. 2 is an exploded view of a temperature raising tray mechanism of the fully automatic urine specific protein analyzer of the present invention;
FIG. 3 is a schematic view of the temperature raising cover;
in the figure:
1-a bottom plate; 2-placing a tray; 201-reaction cup holder; 2011-reaction cup placing hole; 202-sample reagent rack; 2021-ureter placement hole; 2022-reagent placement wells; 3-a refrigerating disc; 4-a heat preservation component; 401-inner heat preservation ring; 402-outer heat preservation ring; 5-semiconductor refrigerating sheet; 6-a radiator; 7-a heat dissipation fan; 8-a fan mounting bracket; 10-a rotating electrical machine; 11-spindle turntable; 12-a frame connecting column; 13-a refrigeration tray mounting post; 14-insulating ring mounting columns; 15-temperature raising cover; 1501-placing a window; 1502-a sample port; 16-detecting the cover plate; 1601-limit baffle.
Detailed Description
The present invention will be described in further detail with reference to the following drawings and specific examples.
As shown in figures 1-2, the temperature raising tray mechanism of the fully automatic urine specific protein analyzer comprises a bottom plate 1 and a placing tray 2.
The placement tray 2 includes a reaction cup holder 201 and a sample reagent holder 202. The reaction cup holder 201 is annular, and the reaction cup holder 201 is evenly provided with a plurality of reaction cup placing holes 2011 along the circumference. The reaction cup holder 201 comprises a plurality of fan-shaped cup holder sheets. The sample reagent rack 202 comprises an upper rack body and a lower rack body, which are fixedly connected through a plurality of rack body connecting columns 12. The upper frame body and the lower frame body are both disc-shaped. A plurality of urine collecting tube placing holes 2021 and reagent placing holes 2022 are uniformly arranged on the upper frame body along the circumferential direction. The reaction cup holder 201 is fixedly connected to the edge of the upper holder body. Therefore, the reaction cup holder 201 and the sample reagent holder 202 are separately arranged, so that the temperature transmission between the reaction cup holder 201 and the sample reagent holder 202 is slow.
The bottom of the lower frame body is provided with a spindle turntable 11, the spindle turntable 11 is connected with a rotating motor 10, and the rotating motor 10 is fixedly installed on the bottom plate 1.
The lower frame body is provided with a refrigeration disc 3 below, and the refrigeration disc 3 is fixedly connected to the bottom plate 1 through a plurality of refrigeration disc mounting columns 13. And a heat preservation component 4 is arranged below the reaction cup holder 201 and the upper holder body. Go up support body, heat preservation part 4 and refrigeration dish 3 and enclose into accommodation space one, reaction glass stand 201, heat preservation part 4 enclose into accommodation space two, be equipped with the heater block in the accommodation space two. The heating component can be a heating belt wound on the outer wall of the inner heat-preservation ring 401.
In this embodiment, the heat insulating member 4 includes an inner heat insulating ring 401 and an outer heat insulating ring 402, the inner heat insulating ring 401 is fixedly connected to the edge of the refrigerating disc 3, and the outer heat insulating ring 402 is disposed on the periphery of the inner heat insulating ring 401. The outer heat-insulating ring 402 is mounted on the bottom plate 1 through a plurality of heat-insulating ring mounting columns 14.
The bottom of refrigeration dish 3 is equipped with a plurality of semiconductor refrigeration pieces 5, semiconductor refrigeration piece 5 includes cold junction and hot junction, the cold junction of semiconductor refrigeration piece 5 with refrigeration dish 3 contact. The semiconductor refrigeration device is characterized in that a radiator 6 is arranged at the hot end of the semiconductor refrigeration sheet 5, the radiator 6 is connected with a radiating fan 7, and the radiating fan 7 is installed below the radiator 6 through a fan installation support 8.
The semiconductor chilling plate 5 is a means for heat transfer. When a current passes through a thermocouple pair formed by connecting an N-type semiconductor material and a P-type semiconductor material, heat transfer can be generated between the two ends, and the heat can be transferred from one end to the other end, so that temperature difference is generated to form a cold end and a hot end. But the semiconductor itself presents a resistance that generates heat when current passes through the semiconductor, thereby affecting heat transfer. But the heat between the two plates is also transferred through the air and the semiconductor material itself in a reverse direction. When the cold end and the hot end reach a certain temperature difference and the heat transfer amounts of the two types are equal, a balance point is reached, and the positive heat transfer and the reverse heat transfer are mutually offset. The temperature of the cold and hot ends will not change continuously. In order to reach lower temperature, the temperature of the hot end can be reduced by adopting a heat dissipation mode and the like.
The heat dissipation fan 7 and the heat sink 6 mainly dissipate heat from the hot end of the semiconductor cooling fin 5. The temperature difference between the cold end and the hot end of the semiconductor refrigerating sheet 5 can reach 40-65 degrees, and if the temperature of the hot end is reduced in an active heat dissipation mode, the temperature of the cold end can be correspondingly reduced, so that the lower temperature is reached.
The temperature raising tray mechanism further comprises a temperature raising cover 15, as shown in fig. 3, a placing window 1501 and a sampling port 1502 are arranged on the temperature raising cover 15, a detection cover plate 16 is arranged at the place of the placing window 1501, and the detection cover plate 16 is rotatably connected with the temperature raising cover 15. And a limit baffle 1601 is arranged on the detection cover plate 16.
The temperature raising tray mechanism comprises a reaction cup placing part and a sample reagent placing part, wherein the reaction cup placing part and the sample reagent placing part are respectively used for placing reaction cups, samples and reagents which are suitable for different temperatures. The sample reagent placing part, the heat preservation part and the refrigerating disc enclose a first accommodating space for accommodating a sample and a reagent, and the sample and the reagent are refrigerated in the first accommodating space; the reaction cup placing part and the heat preservation part enclose a second accommodating space for accommodating the reaction cup, and the sample cup is kept at the temperature of the human body environment in the second accommodating space.
The temperature raising tray mechanism of the invention has uniform heating and small temperature deviation, so that the analysis and diagnosis result is accurate.
Other embodiments of the present invention than the preferred embodiments described above will be apparent to those skilled in the art from the present invention, and various changes and modifications can be made therein without departing from the spirit of the present invention as defined in the appended claims.

Claims (8)

1. The temperature raising plate mechanism of the full-automatic urine specific protein analyzer is characterized by comprising a placing tray (2), wherein the placing tray (2) comprises a reaction cup placing part and a sample reagent placing part, a refrigerating plate (3) and a heat preservation part (4) are arranged below the placing tray, the sample reagent placing part, the heat preservation part (4) and the refrigerating plate (3) are enclosed to form a first accommodating space for accommodating a sample and a reagent, the reaction cup placing part and the heat preservation part (4) are enclosed to form a second accommodating space for accommodating the reaction cup, and a heating part is arranged in the second accommodating space.
2. The incubation disc mechanism of the fully automatic urine specific protein analyzer as claimed in claim 1, wherein the bottom of the cooling disc (3) is provided with a plurality of semiconductor cooling plates (5), the semiconductor cooling plates (5) comprise a cold end and a hot end, and the cold end of the semiconductor cooling plate (5) is in contact with the cooling disc (3).
3. The temperature raising tray mechanism of the full-automatic urine specific protein analyzer as claimed in claim 2, wherein a heat radiator (6) is arranged at the hot end of the semiconductor refrigeration sheet (5), and the heat radiator (6) is connected with a heat radiation fan (7).
4. The incubator mechanism of the fully automatic urine specific protein analyzer according to claim 1, wherein the placement tray (2) comprises a reaction cup holder (201) and a sample reagent rack (202), the reaction cup placement portion is disposed on the reaction cup holder (201), the sample reagent placement portion is disposed on the sample reagent rack (202), the reaction cup holder (201) has a ring shape, and the reaction cup holder (201) is fixedly mounted on an edge of the sample reagent rack (202).
5. The temperature raising tray mechanism of the fully automatic urine specific protein analyzer according to claim 4, wherein the reaction cup holder (201) comprises a plurality of fan-ring shaped cup holder pieces.
6. The temperature raising tray mechanism of the fully automatic urine specific protein analyzer according to claim 1, 4 or 5, wherein a plurality of reaction cup placing holes (2011) are uniformly formed in the reaction cup placing portion along the circumferential direction, a plurality of urine collection tube placing holes (2021) and reagent placing holes (2022) are uniformly formed in the sample reagent placing portion along the circumferential direction, and the placing tray (2) is connected with a rotating motor (10).
7. The temperature raising tray mechanism of the fully automatic urine specific protein analyzer according to claim 6, further comprising a temperature raising cover (15), wherein the temperature raising cover (15) is provided with a placing window (1501) and a sampling port (1502), the placing window (1501) is provided with a detecting cover plate (16), and the detecting cover plate (16) is rotatably connected with the temperature raising cover (15).
8. The temperature raising tray mechanism of the fully automatic urine specific protein analyzer as claimed in claim 7, wherein the detection cover plate (16) is provided with a limit baffle (1601).
CN202010473037.1A 2020-05-29 2020-05-29 Temperature raising disc mechanism of full-automatic urine specific protein analyzer Active CN111812340B (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113419576A (en) * 2021-07-08 2021-09-21 安徽伊普诺康生物技术股份有限公司 Temperature control system of protein analyzer

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CN208092069U (en) * 2018-03-13 2018-11-13 张玉兰 Small size automatic chemical illumination immunity analysis instrument
CN208443845U (en) * 2018-07-23 2019-01-29 苏州长光华医生物医学工程有限公司 A kind of incubation disk
CN109580595A (en) * 2017-09-29 2019-04-05 深圳市新产业生物医学工程股份有限公司 Chemiluminescence detector incubates device and reaction disc mechanism
US20190204233A1 (en) * 2017-12-28 2019-07-04 Shenzhen New Industries Biomedical Engineering Co., Ltd. Chemiluminescence Detector and Detection Method Thereof
WO2019137032A1 (en) * 2018-01-09 2019-07-18 苏州长光华医生物医学工程有限公司 Reagent chamber structure

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Publication number Priority date Publication date Assignee Title
US20010049092A1 (en) * 2000-05-31 2001-12-06 Pfizer Inc. Method and device for drug-drug interaction testing sample preparation
JP2004233123A (en) * 2003-01-29 2004-08-19 Fuji Kiki Kogyo Kk Automatic analyzer
CN101566624A (en) * 2008-11-14 2009-10-28 北京量质科技有限公司 Full-automatic medical inspection and detection system
CN106980026A (en) * 2017-03-29 2017-07-25 盐城拜明生物技术有限公司 Automatic chemiluminescence immunoassay detects performs device
CN109580595A (en) * 2017-09-29 2019-04-05 深圳市新产业生物医学工程股份有限公司 Chemiluminescence detector incubates device and reaction disc mechanism
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WO2019137032A1 (en) * 2018-01-09 2019-07-18 苏州长光华医生物医学工程有限公司 Reagent chamber structure
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113419576A (en) * 2021-07-08 2021-09-21 安徽伊普诺康生物技术股份有限公司 Temperature control system of protein analyzer

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