CN111803518A - Liquid trace element, preparation method and application - Google Patents

Liquid trace element, preparation method and application Download PDF

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Publication number
CN111803518A
CN111803518A CN202010709831.1A CN202010709831A CN111803518A CN 111803518 A CN111803518 A CN 111803518A CN 202010709831 A CN202010709831 A CN 202010709831A CN 111803518 A CN111803518 A CN 111803518A
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micro powder
liquid trace
trace element
liquid
trace elements
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CN202010709831.1A
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Chinese (zh)
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李冠玉
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Yantai Guanyu Biotechnology Co ltd
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Yantai Guanyu Biotechnology Co ltd
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Priority to CN202010709831.1A priority Critical patent/CN111803518A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/12Magnesium silicate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/04Sulfur, selenium or tellurium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/26Iron; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/02Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses

Abstract

A liquid microelement, a preparation method and an application thereof, wherein the liquid microelement comprises the following components in percentage by mass: natural rock micro powder: chelating agent: and (3) analytical purification: purified water =1: 0.05-0.1: 0.1-0.5: 1.5 to 3; in the natural rock micro powder, 20-30% of tourmaline micro powder, 20-30% of germanite micro powder, 20-30% of medical stone micro powder, 10-20% of volcanic rock micro powder and 5-10% of selenium ore micro powder. Putting the raw materials into a high-temperature physical reaction kettle at 450 ℃ and under the pressure of 2 multiplied by 105Pa is reacted for 5 hours under the condition of high temperature, high pressure and strong oxidation, and chelation reaction is carried out for at least 96 hours under the condition of 20 ℃; and (3) distilling and separating the rock micro powder at the temperature of 110 ℃ to obtain balanced liquid trace elements, wherein the pH of the liquid trace elements is 7.1-7.6. Can be used for treating diabetic foot, rheumatoid diseases, herpes zoster, and psoriasis.

Description

Liquid trace element, preparation method and application
Technical Field
The invention relates to the technical field of liquid trace elements, in particular to a liquid trace element, a preparation method and application thereof.
Background
The twenty-first century is a century of biological science, and from the medical point of view, in the field of life science, trace elements are a supporting framework of a human body energy source, and the demonstration of genetic gene DNA, protein ATP, ADP and synthetase brings new height to the cognition of the life science and the medicine on the trace elements. The loss of trace elements in the human body is a major factor leading to the dysregulation of the human immune system. The loss of trace element iron can cause iron-deficiency heart disease and iron-deficiency anemia. The deficiency of the trace element copper can cause leucoderma diseases. Diabetes, rheumatoid disease, psoriasis, herpes zoster, etc. are all disorders of the human immune system. How to improve the immunity is a difficult problem in daily life of people.
At present, most top-level life scientists in the world give a very scientific discussion about the role of trace elements in the human body, and more than 70 trace elements are needed in the human body. The trace elements which can be absorbed in daily diet of people are very few at present, because the long-term cultivation of soil can not be maintained, the trace elements in the soil are seriously lost in the aspect of agriculture, and the fruits and vegetables grown by the fertilizer of plant skeletons such as single fertilizer, nitrogen, phosphorus and potassium are used for a long time, the trace elements which are balanced are seriously lost, so that the human body can not absorb the trace elements.
At present, trace elements are widely applied to medical products, such as 21 jin vitamin, multi-vitamin mineral tablets, Ganquiwei tablets and the like, which are all in mineral grade, are mostly synthetic products and are difficult to be directly absorbed by human bodies, and the products are only suitable for adults and are forbidden for pregnant women and children. Because the preparation method is too simple and cannot be applied to human bodies, the research on trace elements is generally only limited to theoretical research but less than the application, the trace elements which can be absorbed by human bodies stay on the level of mineral substances, the absorption of the trace elements by the human bodies is blocked, and the trace elements which can be directly applied by the human bodies are not available at present.
Disclosure of Invention
Therefore, the invention provides a liquid trace element, a preparation method and application thereof, wherein the liquid trace element is prepared by reducing mineral substances rich in trace elements to an initial trace element stage in a physical mode and a chemical mode through a thermodynamic principle.
In order to achieve the above purpose, the invention provides the following technical scheme: the liquid trace element comprises the following raw materials in percentage by mass:
natural rock micro powder: chelating agent: and (3) analytical purification: purified water =1: 0.05-0.1: 0.1-0.5: 1.5 to 3;
the natural rock micro powder comprises the following raw materials in percentage by mass: 20-30% of tourmaline micro powder, 20-30% of germanite micro powder, 20-30% of medical stone micro powder, 10-20% of volcanic stone micro powder and 5-10% of selenium ore micro powder.
As a preferable scheme of the liquid trace element, the liquid trace element comprises the following raw materials in percentage by mass: natural rock micro powder: chelating agent: and (3) analytical purification: purified water =1:0.008:0.3: 2.
As a preferable scheme of liquid trace elements, the natural rock micro powder comprises the following raw materials in percentage by mass: 25% of tourmaline micro powder, 25% of germanite micro powder, 25% of medical stone micro powder, 15% of volcanic rock micro powder and 10% of selenium ore micro powder.
As a preferable mode of the liquid trace elements, the liquid trace elements include the following types: carbon, hydrogen, oxygen, nitrogen, phosphorus, sulfur, calcium, magnesium, sodium, potassium, iron, zinc, copper, manganese, chromium, selenium, molybdenum, cobalt, and fluorine.
The trace elements are catalyst speed of biological enzyme, and can regulate organism balance. The microelement catalytic enzyme has high efficiency, can catalyze plant enzymes for plants, and can catalyze animal protease for animals. The trace elements of the liquid prepared by the invention can be widely applied to the aspects of medicine, health care, beauty treatment, soil improvement, environmental protection, planting, breeding and the like. Does not cause secondary pollution to the environment, and is a non-toxic, high-efficiency and environment-friendly biological high-tech product.
The invention also provides a preparation method of the liquid trace element, which comprises the following steps:
(1) respectively crushing tourmaline, germanite, medical stone, volcanic rock and selenium ore into powder of 10000 meshes below to nanometer, respectively preparing into micro powder of various rocks, weighing corresponding rock micro powder according to the composition raw materials and mass percentage of the rock micro powder, putting the rock micro powder into a high-temperature physical reaction kettle, and performing reaction at the temperature of 450 ℃ and the pressure of 2 multiplied by 105The Pa reacts for at least 5 hours under the high-temperature high-pressure oxidation condition to form natural rock micro powder;
(2) naturally cooling the natural rock micro powder in the step (1) to 150 ℃, adding purified water, analytically pure and a chelating agent, and carrying out a chelating reaction for at least 96 hours at a temperature of 80 ℃;
(3) and (3) distilling and separating rock micro powder from a product obtained after the chelation reaction in the step (2) for at least 96 hours at the temperature of 110 ℃ to obtain balanced liquid trace elements, wherein the pH value of the liquid trace elements is 7.1-7.6.
The liquid trace elements are used for bubble therapy of diabetic foot, bubble therapy of rheumatoid disease, bubble therapy of herpes zoster disease and bubble therapy of psoriasis.
By adopting the technical scheme, the invention has the following beneficial effects:
(1) the liquid trace elements can be chelated with various complex enzymes, so that the trace elements can be quickly and effectively supplemented, the activity of the enzyme is improved, and the action efficiency of the enzyme is improved.
(2) The invention aims at animals and can improve the activity of animal protease to promote the healthy growth of the animals. The activity of plant enzymes can be improved aiming at plants to promote the healthy growth of the plants. The prepared liquid trace elements are widely applied to the fields of medical use, planting, breeding and the like.
(3) The preparation method is simple, easy to operate and low in production cost, and can be widely applied to production.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below. It should be apparent that the drawings in the following description are merely exemplary, and that other embodiments can be derived from the drawings provided by those of ordinary skill in the art without inventive effort.
FIG. 1 is a patient information document using the liquid trace elements of the present invention provided in an example of the present invention;
FIG. 2 is a patient's condition examination report using the liquid trace elements of the present invention provided in an example of the present invention;
FIG. 3 is a pre-treatment biped condition of a patient provided in an embodiment of the invention using liquid trace elements of the invention;
FIG. 4 is a foot bath of a patient with liquid trace elements of the present invention provided in an embodiment of the present invention;
FIG. 5 shows the healing condition of a patient after soaking feet for one week, wherein the patient is provided with the liquid trace elements of the invention in the example of the invention;
FIG. 6 is a pre-herpetic bubble therapy chart of a patient with the liquid trace elements of the present invention;
FIG. 7 is a photograph of a patient undergoing herpes zoster bubble therapy with liquid trace elements of the invention for one month;
FIG. 8 is a report of a test report of a patient before performing bubble therapy for rheumatoid diseases with the liquid trace elements of the present invention;
FIG. 9 is a report of the examination of a patient after performing bubble therapy for rheumatoid arthritis with the liquid trace elements of the present invention;
FIG. 10 is a first page of a liquid trace element detection report provided in an embodiment of the present invention;
FIG. 11 is a second page of a liquid trace element detection report according to an embodiment of the present invention;
fig. 12 is a third page of a liquid trace element detection report provided in the embodiment of the present invention.
Detailed Description
The present invention is described in terms of particular embodiments, other advantages and features of the invention will become apparent to those skilled in the art from the following disclosure, and it is to be understood that the described embodiments are merely exemplary of the invention and that it is not intended to limit the invention to the particular embodiments disclosed. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The embodiment of the invention provides a liquid trace element, which comprises the following raw materials in parts by mass: 100g of natural rock micro powder, 5g of chelating agent, 10g of analytical purity and 150g of purified water; the natural rock micro powder comprises the following raw materials in parts by mass: 25g of tourmaline micro powder, 25g of germanite micro powder, 25g of medical stone micro powder, 10g of vesuvianite micro powder and 5g of selenium ore micro powder.
Referring to fig. 10, fig. 11 and fig. 12, in the embodiment of the present invention, the tourmaline stone used contains all the macroelements required by animals, such as K, Na, Ca, Mg, etc., and trace elements such as Cu, Mo, etc., and rare earth elements, and there are more than 50 kinds of trace elements in total. A large amount of germanium in germanite used exists in silicate ores, sulfide ores, and various types of coal in a dispersed state for various metals. The medical stone contains all macroelements required by animals, such as K, Na, Ca and Mg, and trace elements such as Cu and Mo and rare earth elements, and is about 58 kinds. The adopted volcanic rock contains dozens of mineral substances and trace elements such as Na, Mg, Al, Si, Ca, Ti, Mn, Fe, Ni, Co, Mo and the like. The adopted selenium ore is rich in Se element. The natural rock contains rich trace elements, the natural rock micro powder is prepared through physical high temperature, water is added for mixing, and after the natural rock micro powder is chelated with a chelating agent and analytically pure, the trace elements can be balanced to more than 50 liquid trace elements.
Among them, molybdenum is an important constituent of various enzymes, and is involved in the utilization of iron in the human body, and can prevent anemia, promote development, and aid in the metabolism of carbohydrates and fats. Maintaining myocardial energy metabolism and preventing keshan disease. Maintaining elasticity of artery, and preventing cardiovascular diseases. Maintaining the immune function of human body. Regulating thyroid gland. Preventing dental caries, renal calculus and cancer. Molybdenum is an important component that makes up the iris of the eye. Effects of strontium on mesenchymal stem cells of bone marrow. Studies show that strontium can regulate differentiation of MSCs (bone marrow mesenchymal stem cells) to osteoblasts and promote synthesis and precipitation of bone matrix proteins. Therefore, strontium has an osteoblast differentiation and osteogenesis promoting effect. Effect of strontium on osteoblasts and osteoclasts: strontium can improve bone metabolism, prevent bone loss, and improve bone quality of osteoporosis animals.
The preparation steps of the liquid trace elements in the embodiment of the invention comprise:
(1) respectively crushing tourmaline, germanite, medical stone, volcanic rock and selenium ore into powder of 10000 meshes below to nanometer, respectively preparing into micro powder of various rocks, weighing corresponding rock micro powder according to the composition raw materials and mass percentage of the rock micro powder, putting the rock micro powder into a high-temperature physical reaction kettle, and performing reaction at the temperature of 450 ℃ and the pressure of 2 multiplied by 105The reaction is carried out for 5 hours under the high-temperature high-pressure oxidation condition of Pa to form natural rock micro powder;
(2) naturally cooling the natural rock micro powder in the step (1) to room temperature, then adding purified water, analytical reagent and chelating agent, and carrying out chelation reaction for 96h at the temperature of 20 ℃;
(3) and (3) distilling and separating rock micro powder from a product obtained after the chelation reaction in the step (2) for 96 hours at the temperature of 110 ℃ to obtain balanced liquid trace elements, wherein the pH of the liquid trace elements is 7.1-7.6.
The liquid trace elements of the embodiment are applied to medical treatment and bubble therapy of diabetic feet, so that fester wounds can be healed to avoid suffering from amputation. The liquid trace element bubble therapy for rheumatoid patients relieves pain and restores adenine and guanine to enable uric acid to recover normal. The liquid trace element bubble therapy for the herpes zoster patient can quickly relieve pain and recover. The psoriasis patient can recover to normal skin state by the liquid trace element bubble therapy. The specific part of the application test results are as follows:
referring to fig. 1 and 2, a female of the south of china, Guangdong, with type II diabetes, had diabetic feet with complications, and 7 ulcers on both feet were examined in the hospital of people in Gao Zhou, 7 months, and referring to fig. 3, skin ulcers with a size of about 3.0cm × 3.0cm were seen on both feet, scabs were seen, and a little pus was formed under the scabs. Referring to fig. 4, after one week of bubble therapy, the skin ulcer is obviously relieved, the red swelling subsides, the scab heals, the pus disappears and no tendency of continuous ulcer develops for the ladies to take the liquid trace elements for bubble therapy, referring to fig. 5. It can be seen that the liquid trace elements of the present invention can heal ulcerated wounds without suffering amputation.
Referring to fig. 6, a patient who does not want to leak information has herpes zoster on the upper body skin, and the liquid trace element bubble therapy of the invention is adopted. Referring to fig. 7, after one month, the area of the herpes zoster is obviously reduced, the herpes zoster trace is lightened, the pain and itch feeling of a patient after bubble therapy is obviously relieved, and after three times of bubble therapy, the pain is avoided, and the rehabilitation effect is obvious.
Comparing fig. 8 and 9, the test report is for a more than 30 year rheumatoid patient who has malformed a knee joint and then developed a swollen knee joint, and who is also ventilated. The liquid trace elements are adopted, and the time from the beginning of soaking in No. 4 and No. 10 to No. 5 and No. 18 is zero and eight days in one month. Before bubble therapy, the patient can not walk by himself, people around the patient can know the bubble therapy, and after the bubble therapy, the patient can walk, can freely move to a hospital, moves flexibly, and walks with legs easily, so that the patient can take care of other patients who need to be operated at home.
The patient had a rheumatoid factor result of <3 and uric acid result of 406.47 before bubble therapy, and a rheumatoid factor result of <17 and uric acid result of 258.35 after bubble therapy. Rheumatoid Factor (RF) is an antibody against an antigenic determinant of the Fc fragment of human or animal IgG molecules, and is an autoantibody targeting denatured IgG. The closer the human median value is to 20, the less rheumatoid disease. Uric acid is an index reflecting ventilation, and the higher the uric acid value is, the more serious the ventilation is. By comparing the examination reports of the patient before and after bubble therapy, the rheumatoid disease and ventilation of the patient are improved.
Although the invention has been described in detail above with reference to a general description and specific examples, it will be apparent to one skilled in the art that modifications or improvements may be made thereto based on the invention. Accordingly, such modifications and improvements are intended to be within the scope of the invention as claimed.

Claims (6)

1. The liquid trace element is characterized by comprising the following raw materials in percentage by mass:
natural rock micro powder: chelating agent: and (3) analytical purification: purified water =1: 0.05-0.1: 0.1-0.5: 1.5 to 3;
the natural rock micro powder comprises the following raw materials in percentage by mass: 20-30% of tourmaline micro powder, 20-30% of germanite micro powder, 20-30% of medical stone micro powder, 10-20% of volcanic stone micro powder and 5-10% of selenium ore micro powder.
2. The liquid trace element according to claim 1, wherein the liquid trace element comprises the following raw materials in percentage by mass:
natural rock micro powder: chelating agent: and (3) analytical purification: purified water =1:0.008:0.3: 2.
3. The liquid trace element according to claim 1, wherein the natural rock micro powder comprises the following raw materials in percentage by mass: 25% of tourmaline micro powder, 25% of germanite micro powder, 25% of medical stone micro powder, 15% of volcanic rock micro powder and 10% of selenium ore micro powder.
4. A liquid trace element according to claim 1, wherein the liquid trace element comprises the following species: carbon, hydrogen, oxygen, nitrogen, phosphorus, sulfur, calcium, magnesium, sodium, potassium, iron, zinc, copper, manganese, chromium, selenium, molybdenum, cobalt, and fluorine.
5. The preparation method of the liquid trace element is characterized by comprising the following steps of:
(1) respectively crushing tourmaline, germanite, medical stone, volcanic rock and selenium ore into powder of 10000 meshes below to nanometer, respectively preparing into micro powder of various rocks, weighing corresponding rock micro powder according to the composition raw materials and mass percentage of the rock micro powder, putting the rock micro powder into a high-temperature physical reaction kettle, and performing reaction at the temperature of 450 ℃ and the pressure of 2 multiplied by 105The Pa reacts for at least 5 hours under the high-temperature high-pressure oxidation condition to form natural rock micro powder;
(2) naturally cooling the natural rock micro powder in the step (1) to 150 ℃, adding purified water, analytically pure and a chelating agent, and carrying out a chelating reaction for at least 96 hours at a temperature of 80 ℃;
(3) and (3) distilling and separating rock micro powder from a product obtained after the chelation reaction in the step (2) for at least 96 hours at the temperature of 110 ℃ to obtain balanced liquid trace elements, wherein the pH value of the liquid trace elements is 7.1-7.6.
6. A liquid trace element according to claims 1 to 4, for use in bubble therapy of diabetic foot, rheumatoid, herpes zoster and psoriasis.
CN202010709831.1A 2020-07-22 2020-07-22 Liquid trace element, preparation method and application Pending CN111803518A (en)

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Application Number Priority Date Filing Date Title
CN202010709831.1A CN111803518A (en) 2020-07-22 2020-07-22 Liquid trace element, preparation method and application

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101268997A (en) * 2008-01-14 2008-09-24 尹吉山 Complexing form wash and bath liquid of natural mineral matter and micro-element, and preparation method
CN102579488A (en) * 2012-03-24 2012-07-18 苏州本源生物技术有限公司 Cell nutrient mineral bath material
CN106580756A (en) * 2016-12-21 2017-04-26 湖南御家化妆品制造有限公司 Mineral hot spring water and preparation method and application thereof
CN108774631A (en) * 2018-09-25 2018-11-09 烟台冠玉生物科技有限公司 A kind of preparation method of rock kinases

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101268997A (en) * 2008-01-14 2008-09-24 尹吉山 Complexing form wash and bath liquid of natural mineral matter and micro-element, and preparation method
CN102579488A (en) * 2012-03-24 2012-07-18 苏州本源生物技术有限公司 Cell nutrient mineral bath material
CN106580756A (en) * 2016-12-21 2017-04-26 湖南御家化妆品制造有限公司 Mineral hot spring water and preparation method and application thereof
CN108774631A (en) * 2018-09-25 2018-11-09 烟台冠玉生物科技有限公司 A kind of preparation method of rock kinases

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