CN111801568A - 测定血小板浓度的方法及系统 - Google Patents
测定血小板浓度的方法及系统 Download PDFInfo
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- CN111801568A CN111801568A CN201980011879.0A CN201980011879A CN111801568A CN 111801568 A CN111801568 A CN 111801568A CN 201980011879 A CN201980011879 A CN 201980011879A CN 111801568 A CN111801568 A CN 111801568A
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Abstract
一种分析血液样本中血小板浓度的方法、血液分析系统(100)及存储介质，测定血液样本中血小板浓度的方法包括：将血液样本的第一份与稀释液混合，形成第一悬浮液；将血液样本的第二份与溶血剂和荧光染料混合以溶解红细胞和染色白细胞，形成第二悬浮液；测量第一悬浮液流过小孔的直流阻抗信号；测量第二悬浮液流过光学流动室(20)的光散射信号和荧光信号；分析第一悬浮液的该直流阻抗信号以获取第一血小板分布；分析第二悬浮液的光散射信号和荧光信号以区分血小板和白细胞并获取第二血小板分布；基于第一血小板分布和第二血小板分布确定血液样本的血小板分析数据，如血小板浓度。
Description
PCT国内申请，说明书已公开。
Claims (69)
- PCT国内申请，权利要求书已公开。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNPCT/CN2018/085197 | 2018-04-28 | ||
| CN2018085197 | 2018-04-28 | ||
| PCT/CN2019/084687 WO2019206313A1 (zh) | 2018-04-28 | 2019-04-26 | 测定血小板浓度的方法及系统 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN111801568A true CN111801568A (zh) | 2020-10-20 |
| CN111801568B CN111801568B (zh) | 2024-05-24 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201980011879.0A Active CN111801568B (zh) | 2018-04-28 | 2019-04-26 | 测定血小板浓度的方法及系统 |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US11841358B2 (zh) |
| EP (2) | EP4439582A3 (zh) |
| CN (1) | CN111801568B (zh) |
| WO (1) | WO2019206313A1 (zh) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114047109A (zh) * | 2022-01-11 | 2022-02-15 | 深圳市帝迈生物技术有限公司 | 一种样本分析仪及其计数方法 |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019206313A1 (zh) * | 2018-04-28 | 2019-10-31 | 深圳迈瑞生物医疗电子股份有限公司 | 测定血小板浓度的方法及系统 |
| CN111337392A (zh) * | 2020-02-28 | 2020-06-26 | 清华大学深圳国际研究生院 | 一种悬浮颗粒偏振荧光同步测量装置 |
| CN114729871A (zh) * | 2021-08-05 | 2022-07-08 | 深圳迈瑞动物医疗科技有限公司 | 一种样本分析装置、动物用分析装置和样本分析方法 |
| CN116952805A (zh) | 2022-04-14 | 2023-10-27 | 深圳迈瑞生物医疗电子股份有限公司 | 样本分析仪以及血小板计数方法 |
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| US5874310A (en) * | 1997-11-21 | 1999-02-23 | Coulter International Corp. | Method for differentiation of nucleated red blood cells |
| CN1323395A (zh) * | 1998-10-20 | 2001-11-21 | 库尔特国际公司 | 鉴别网状细胞的试剂组合物和方法 |
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-
2019
- 2019-04-26 WO PCT/CN2019/084687 patent/WO2019206313A1/zh unknown
- 2019-04-26 EP EP24180348.5A patent/EP4439582A3/en active Pending
- 2019-04-26 CN CN201980011879.0A patent/CN111801568B/zh active Active
- 2019-04-26 EP EP19792132.3A patent/EP3789751B1/en active Active
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2020
- 2020-10-20 US US17/075,603 patent/US11841358B2/en active Active
-
2023
- 2023-12-11 US US18/536,047 patent/US20240230621A9/en active Pending
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| CN1323395A (zh) * | 1998-10-20 | 2001-11-21 | 库尔特国际公司 | 鉴别网状细胞的试剂组合物和方法 |
| US6525807B1 (en) * | 1999-01-21 | 2003-02-25 | Sysmex Corporation | Particle analyzing apparatus |
| US20040038413A1 (en) * | 2002-08-23 | 2004-02-26 | Kramer Donald L. | Method and apparatus for differentiating blood cells using back-scatter |
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| US20240230621A9 (en) | 2024-07-11 |
| US11841358B2 (en) | 2023-12-12 |
| US20240133864A1 (en) | 2024-04-25 |
| WO2019206313A1 (zh) | 2019-10-31 |
| US20210033593A1 (en) | 2021-02-04 |
| EP4439582A3 (en) | 2024-10-16 |
| EP4439582A2 (en) | 2024-10-02 |
| CN111801568B (zh) | 2024-05-24 |
| EP3789751A1 (en) | 2021-03-10 |
| EP3789751C0 (en) | 2024-06-26 |
| EP3789751B1 (en) | 2024-06-26 |
| EP3789751A4 (en) | 2021-06-30 |
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