CN111743844A - Traditional Chinese medicine compound gargle and preparation method thereof - Google Patents

Traditional Chinese medicine compound gargle and preparation method thereof Download PDF

Info

Publication number
CN111743844A
CN111743844A CN202010660550.1A CN202010660550A CN111743844A CN 111743844 A CN111743844 A CN 111743844A CN 202010660550 A CN202010660550 A CN 202010660550A CN 111743844 A CN111743844 A CN 111743844A
Authority
CN
China
Prior art keywords
parts
chinese medicine
traditional chinese
cleaning
positioning
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202010660550.1A
Other languages
Chinese (zh)
Inventor
孙盼盼
金鑫
洪蕊
陶秀彬
王晓晔
年四辉
姚银春
刘爽
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yijishan Hospital of Wannan Medical College
Original Assignee
Yijishan Hospital of Wannan Medical College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yijishan Hospital of Wannan Medical College filed Critical Yijishan Hospital of Wannan Medical College
Priority to CN202010660550.1A priority Critical patent/CN111743844A/en
Publication of CN111743844A publication Critical patent/CN111743844A/en
Pending legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287Chrysanthemum, e.g. daisy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/58Meliaceae (Chinaberry or Mahogany family), e.g. Azadirachta (neem)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/756Phellodendron, e.g. corktree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/77Sapindaceae (Soapberry family), e.g. lychee or soapberry
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968Ophiopogon (Lilyturf)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02Local antiseptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B08CLEANING
    • B08BCLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B13/00Accessories or details of general applicability for machines or apparatus for cleaning
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B08CLEANING
    • B08BCLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B3/00Cleaning by methods involving the use or presence of liquid or steam
    • B08B3/04Cleaning involving contact with liquid
    • B08B3/044Cleaning involving contact with liquid using agitated containers in which the liquid and articles or material are placed
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26DRYING
    • F26BDRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B21/00Arrangements or duct systems, e.g. in combination with pallet boxes, for supplying and controlling air or gases for drying solid materials or objects
    • F26B21/004Nozzle assemblies; Air knives; Air distributors; Blow boxes
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26DRYING
    • F26BDRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B25/00Details of general application not covered by group F26B21/00 or F26B23/00
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26DRYING
    • F26BDRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B9/00Machines or apparatus for drying solid materials or objects at rest or with only local agitation; Domestic airing cupboards
    • F26B9/06Machines or apparatus for drying solid materials or objects at rest or with only local agitation; Domestic airing cupboards in stationary drums or chambers

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Birds (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a traditional Chinese medicine compound mouthwash, and relates to the technical field of oral health care, and the traditional Chinese medicine compound mouthwash is prepared from the following raw materials in parts by weight: 20-40 parts of wild chrysanthemum, 25-35 parts of golden cypress, 10-25 parts of honeysuckle, 30-40 parts of maimen, 40-60 parts of lychee seed, 2-8 parts of mirabilis jalapa, 5-10 parts of chamomile, 10-15 parts of cortex meliae, 1-5 parts of preservative and 10-15 parts of sweetener.

Description

Traditional Chinese medicine compound gargle and preparation method thereof
Technical Field
The invention belongs to the technical field of oral health care, and particularly relates to a preparation method of a traditional Chinese medicine compound gargle.
Background
Dental plaque is a main factor inducing oral diseases, pathogenic bacteria are generally accumulated in the dental plaque, and the occurrence of the oral diseases such as periodontal diseases, dental caries, inflammation and the like can be effectively prevented only by inhibiting the growth of the dental plaque.
Gargling is an auxiliary tooth cleaning measure, has good antibacterial effect, and can be matched with toothpaste for further enhancing the tooth cleaning effect. The principle is as follows: the integrity of the biofilm on the plaque surface is mechanically disrupted by brushing the teeth while reducing the number of bacteria in the plaque. The bacteriostatic agent in the gargle directly plays a role of sterilization through the damaged biological film on the surface of the bacterial plaque, thereby improving the effects of inhibiting the formation of the bacterial plaque and killing bacterial plaque. Therefore, the quality of the gargle directly affects the prevention effect of oral diseases.
The cleaning and drying of the raw material medicines belong to an essential production process in the processing process of the gargle, at present, the cleaning and drying are generally divided into two independent processes which are respectively carried out in different devices, and the efficiency is low.
Disclosure of Invention
The invention aims to provide a preparation method of a traditional Chinese medicine compound gargle, which aims to overcome the defects caused by the prior art.
A traditional Chinese medicine compound mouthwash is prepared from the following raw materials in parts by weight: 20-40 parts of wild chrysanthemum, 25-35 parts of golden cypress, 10-25 parts of honeysuckle, 30-40 parts of maimendong, 40-60 parts of lychee seed, 2-8 parts of mirabilis jalapa, 5-10 parts of chamomile, 10-15 parts of cortex meliae, 1-5 parts of preservative and 10-15 parts of sweetener.
Preferably, the traditional Chinese medicine compound mouthwash is prepared from the following raw materials in parts by weight: 30 parts of wild chrysanthemum flower, 30 parts of golden cypress, 20 parts of honeysuckle flower, 35 parts of maimendong, 50 parts of lychee seed, 5 parts of mirabilis jalapa, 8 parts of chamomile, 12 parts of cortex meliae, 3 parts of preservative and 12 parts of sweetener.
Preferably, the sweetener is one or a mixture of several of stevia rebaudiana, xylitol, sorbitol and alitame mixed according to any ratio.
A preparation method of a traditional Chinese medicine compound gargle comprises the following steps:
(1) putting wild chrysanthemum flower, amur corktree bark, honeysuckle flower, maidenhair, lychee seed, mirabilis jalapa, chamomile and chinaberry bark in the raw material medicines into a cleaning and drying device according to the proportion for cleaning, then drying the raw material medicines by using the cleaning and drying device, pumping the dried raw material medicines into a crusher by using suction equipment, crushing the raw material medicines by using the crusher, and sieving the crushed raw material medicines by using a 105-fold 110-mesh sieve;
(2) adding deionized water into the crushed raw material medicines in the step (1), decocting for 10-25 minutes, filtering while hot, and adding a certain amount of deionized water into the filtrate;
(3) grinding the sweetening agent and the preservative into powder, adding the powder into the filtrate obtained in the step (2), heating in a water bath at 52-58 ℃, stirring for 1-2 hours, cooling, filtering, sterilizing and subpackaging to obtain the traditional Chinese medicine compound mouthwash.
Preferably, the cleaning and drying device comprises a box body, a box cover, a cleaning cage, side supports, a rotating mechanism and a power mechanism, wherein the box body is of a shell structure with an upper end open, the box cover is installed at the top of the box body, the cleaning cage is provided with two parts which are symmetrically installed at the upper end and the lower end of each side support, the cleaning cage is rotatably connected onto the side supports through a driving shaft, when the cleaning cage is in a vertical position, the driving shaft can be connected with the power mechanism to drive the cleaning cage to rotate automatically, a rotating sleeve is installed at the outer side of each side support and rotatably connected onto the side wall of the box body through a bearing, the rotating sleeve is further connected to the rotating mechanism to realize the rotation of the side supports, a horizontal partition plate is further arranged between the two side supports and divides the box body into a drying chamber at the upper part and a cleaning chamber at the, the outer end of the supporting shaft is connected with a positioning shaft with a polygonal cross section, the outer side of the box body is provided with a fixing plate, and the fixing plate is provided with a positioning hole matched with the positioning shaft and used for limiting the positioning shaft;
in the box, be located the width direction of baffle and still the symmetry install two breakwaters, the one end of breakwater rotates through the pivot to be connected on the inner wall of box, leave the clearance between the other end of breakwater and the baffle, the pivot passes the lateral wall of box and the cover is equipped with the torsional spring and can keeps the horizontality in order to realize the breakwater, still install on the baffle and shelter from drainage mechanism to be used for realizing that the washing cage can order about the breakwater steady when switching to vertical position, open the wash port on the baffle and realize the location of collateral branch frame.
Preferably, the blocking and draining mechanism comprises two guide blocks, a connecting rod, a positioning plate, a blocking plate and a plug, the two guide blocks are symmetrically arranged at two ends of the partition plate in the length direction, a guide hole matched with the guide blocks is formed in the partition plate so that the guide blocks can slide up and down, the lower end of each guide block is connected with the blocking plate, the plug is provided with a plurality of water discharge holes which are arranged on the top surface of the blocking plate in a linear array mode and used for blocking the partition plate, and a plurality of reset springs are connected between the blocking plate and the partition plate;
step surfaces are arranged at two ends of the partition board in the width direction, the two step surfaces are arranged in a central symmetry manner, the positioning board is connected to the step surfaces in a sliding manner by means of a sliding block on the positioning board and a sliding groove on the partition board, the upper end surface of the positioning board is also connected with a hinge seat, one end of a connecting rod is hinged to the hinge seat, and the other end of the connecting rod is hinged to the guide block;
the top of guide block is circular-arc and its highest point still is equipped with a constant head tank, and the inboard of every collateral branch frame is equipped with two and constant head tank complex locating levers, and two locating levers are symmetrical in the length direction of collateral branch frame and are set up.
Preferably, the rotating mechanism comprises a rotating motor, a motor base I, a belt pulley I and a belt pulley II, the rotating motor is installed on the outer side of the box body through the motor base I, the output end of the rotating motor is connected to the belt pulley I, the belt pulley I is connected to the belt pulley II through a belt, and the belt pulley II is installed on a rotating sleeve located on one side of the rotating motor.
Preferably, power unit includes driving motor, motor cabinet two, supporting seat, pneumatic cylinder and friction disk one, and driving motor passes through motor cabinet two sliding connection on the supporting seat, and the outer end of motor cabinet two is connected to the output of pneumatic cylinder, and the pneumatic cylinder is installed on the supporting seat and is used for realizing the horizontal migration of motor cabinet two, and driving motor's output passes the lateral wall of box and is connected to friction disk one, and the outer end of drive shaft is connected with friction disk two.
Preferably, the side wall of the box body positioned in the drying chamber is provided with an air inlet pipe, the box cover is provided with an air outlet, and the side wall of the box body positioned in the cleaning process is provided with a water inlet pipe and a water outlet pipe.
The invention has the advantages that:
(1) the traditional Chinese medicine mouthwash disclosed by the invention can effectively kill harmful flora in the oral cavity, help to restore balance of other flora in the oral cavity, can help vital qi, resist pathogen going out and quickly treat oral fungal infection;
(2) the invention can effectively reduce the side effect of the medicinal gargle, the chinaberry bark and the lychee seed are main medicinal components of the gargle, and the gargle has good specific inhibition effect on helicobacter pylori, is beneficial to maintaining the microecological balance of the oral cavity and reduces the side effect of the medicinal gargle;
(3) the preparation method is simple and easy to operate, adopts a double-station treatment mode in the same box body by matching with a special cleaning and drying device, simplifies the structural layout, saves the equipment cost, and can also improve the cleaning and drying efficiency, and the shielding and drainage mechanism in the preparation method can respectively realize the three purposes of driving the water baffle to be stable, opening the drainage hole on the partition plate and positioning the side bracket.
Drawings
Fig. 1 is a process flow chart of the preparation method of the traditional Chinese medicine compound mouthwash of the invention.
Fig. 2 and 3 are schematic structural diagrams of the cleaning and drying device in different viewing angles.
Fig. 4 is a partially enlarged view of a portion a in fig. 2.
Fig. 5 and 6 are schematic structural diagrams of the cleaning and drying device with the box body, the box cover and the water baffle removed from the device from different viewing angles.
Fig. 7 is a schematic diagram of the cleaning cage in the cleaning and drying device in the switching operation state.
Fig. 8 is a schematic structural view of the separator of the present invention.
FIG. 9 is a schematic structural view of the side stand of the present invention.
FIG. 10 is a schematic diagram of the cleaning cage of the present invention.
Wherein: 1-box body, 2-box cover, 3-cleaning cage, 4-side bracket, 5-rotating mechanism, 51-rotating motor, 52-motor base I, 53-belt pulley I, 54-belt pulley II, 6-power mechanism, 61-driving motor, 62-motor base II, 63-supporting base, 64-hydraulic cylinder, 65-friction disk I, 66-friction disk II, 7-driving shaft, 8-rotating sleeve, 9-partition plate, 10-drying chamber, 11-cleaning chamber, 12-supporting shaft, 13-positioning shaft, 14-fixing plate, 15-water baffle, 16-rotating shaft, 17-positioning rod, 18-torsion spring, 19-shielding drainage mechanism, 191-guide block, 192-connecting rod, 193-positioning plate, 194-blocking plate, 195-blocking head, 196-water discharging hole, 197-guide hole, 198-step surface, 199-notch, 1910-sliding groove, 1911-hinged seat, 1912-positioning groove, 1913-return spring, 1913-, 20-air inlet pipe, 21-air outlet, 22-water inlet pipe, 23-water discharging pipe and 24-side plate.
Detailed Description
In order to make the technical means, the creation characteristics, the achievement purposes and the effects of the invention easy to understand, the invention is further described with the specific embodiments.
Example 1
As shown in fig. 1, a preparation method of a traditional Chinese medicine compound mouthwash comprises the following steps:
(1) putting wild chrysanthemum flower, amur corktree bark, honeysuckle flower, maidenhair, lychee seed, mirabilis jalapa, chamomile and chinaberry bark in the raw material medicines into a cleaning and drying device according to the proportion for cleaning, then drying the raw material medicines by using the cleaning and drying device, pumping the dried raw material medicines into a crusher by using suction equipment, crushing the raw material medicines by using the crusher, and sieving the crushed raw material medicines by using a 105-fold 110-mesh sieve;
(2) adding deionized water into the crushed raw material medicines in the step (1), decocting for 10-25 minutes, filtering while hot, and adding a certain amount of deionized water into the filtrate;
(3) grinding the sweetening agent and the preservative into powder, adding the powder into the filtrate obtained in the step (2), heating in a water bath at 52-58 ℃, stirring for 1-2 hours, cooling, filtering, sterilizing and subpackaging to obtain the traditional Chinese medicine compound mouthwash.
In the embodiment, the traditional Chinese medicine compound mouthwash is prepared from the following raw materials in parts by weight: 20 parts of wild chrysanthemum, 25 parts of golden cypress, 10 parts of honeysuckle, 30 parts of maimendong, 40 parts of lychee seed, 2 parts of mirabilis jalapa, 5 parts of chamomile, 10-15 parts of cortex meliae, 1 part of preservative and 10 parts of sweetener.
Example 2
A preparation method of a traditional Chinese medicine compound gargle comprises the following steps:
(1) putting wild chrysanthemum flower, amur corktree bark, honeysuckle flower, maidenhair, lychee seed, mirabilis jalapa, chamomile and chinaberry bark in the raw material medicines into a cleaning and drying device according to the proportion for cleaning, then drying the raw material medicines by using the cleaning and drying device, pumping the dried raw material medicines into a crusher by using suction equipment, crushing the raw material medicines by using the crusher, and sieving the crushed raw material medicines by using a 105-fold 110-mesh sieve;
(2) adding deionized water into the crushed raw material medicines in the step (1), decocting for 10-25 minutes, filtering while hot, and adding a certain amount of deionized water into the filtrate;
(3) grinding the sweetening agent and the preservative into powder, adding the powder into the filtrate obtained in the step (2), heating in a water bath at 52-58 ℃, stirring for 1-2 hours, cooling, filtering, sterilizing and subpackaging to obtain the traditional Chinese medicine compound mouthwash.
In the embodiment, the traditional Chinese medicine compound mouthwash is prepared from the following raw materials in parts by weight: 30 parts of wild chrysanthemum flower, 30 parts of golden cypress, 20 parts of honeysuckle flower, 35 parts of maimendong, 50 parts of lychee seed, 5 parts of mirabilis jalapa, 8 parts of chamomile, 12 parts of cortex meliae, 3 parts of preservative and 12 parts of sweetener.
Example 3
A preparation method of a traditional Chinese medicine compound gargle comprises the following steps:
(1) putting wild chrysanthemum flower, amur corktree bark, honeysuckle flower, maidenhair, lychee seed, mirabilis jalapa, chamomile and chinaberry bark in the raw material medicines into a cleaning and drying device according to the proportion for cleaning, then drying the raw material medicines by using the cleaning and drying device, pumping the dried raw material medicines into a crusher by using suction equipment, crushing the raw material medicines by using the crusher, and sieving the crushed raw material medicines by using a 105-fold 110-mesh sieve;
(2) adding deionized water into the crushed raw material medicines in the step (1), decocting for 10-25 minutes, filtering while hot, and adding a certain amount of deionized water into the filtrate;
(3) grinding the sweetening agent and the preservative into powder, adding the powder into the filtrate obtained in the step (2), heating in a water bath at 52-58 ℃, stirring for 1-2 hours, cooling, filtering, sterilizing and subpackaging to obtain the traditional Chinese medicine compound mouthwash.
In the embodiment, the traditional Chinese medicine compound mouthwash is prepared from the following raw materials in parts by weight: 40 parts of wild chrysanthemum flower, 35 parts of golden cypress, 25 parts of honeysuckle flower, 40 parts of maimendong, 60 parts of lychee seed, 8 parts of mirabilis jalapa, 10 parts of chamomile, 15 parts of cortex meliae, 5 parts of preservative and 15 parts of sweetener.
As shown in fig. 2 to 10, in order to achieve better and faster cleaning and drying, the cleaning and drying device of the present invention is designed, and includes a box body 1, a box cover 2, a cleaning cage 3, a side bracket 4, a rotating mechanism 5 and a power mechanism 6, wherein the box body 1 is a shell structure with an opening at the upper end, the box cover 2 is installed at the top of the box body 1, the cleaning cage 3 has two parts and is symmetrically installed at the upper and lower ends of the side bracket 4, the left and right sides of the side bracket 4 are also connected with side plates, wherein the cleaning cage 3 is rotatably connected to the side bracket 4 through a driving shaft 7, when the cleaning cage 3 is in a vertical position, the driving shaft 7 can be connected with the power mechanism 6 to drive the cleaning cage 3 to rotate automatically, the rotating sleeve 8 is installed at the outer side of the side bracket 4, the rotating sleeve 8 is rotatably connected to the side wall of the box body 1 through a, a horizontal partition plate 9 is arranged between the two side brackets 4 and divides the box body 1 into an upper drying chamber 10 and a lower cleaning chamber 11, two ends of the partition plate 9 are connected with support shafts 12, the support shafts 12 penetrate through holes in the side brackets 4 and a rotating sleeve 8, the outer ends of the support shafts 12 are connected with positioning shafts 13 with polygonal cross sections, fixing plates 14 are arranged on the outer sides of the box body 1, and the fixing plates 14 are provided with positioning holes matched with the positioning shafts 13 and used for limiting the positioning shafts 13;
in the box 1, be located the width direction of baffle 9 and still install two breakwaters 15 symmetrically, the one end of breakwater 15 is rotated through pivot 16 and is connected on the inner wall of box 1, leave the clearance between the other end of breakwater 15 and the baffle 9, pivot 16 passes the lateral wall of box 1 and overlaps and be equipped with torsional spring 17 in order to realize that breakwater 15 can keep the horizontality, still install on the baffle 9 and shelter from drainage mechanism 19, and be used for realizing that cleaning cage 3 can order about breakwater 15 steady when switching to vertical position, open wash port 196 on the baffle 9 and realize the location of collateral branch frame 4.
In this embodiment, the blocking and draining mechanism 19 includes two guide blocks 191, a connecting rod 192, a positioning plate 193, a blocking plate 194 and a plug 195, the two guide blocks 191 are symmetrically installed at two ends of the partition plate 9 in the length direction, the partition plate 9 is provided with a guide hole 197 matched with the guide blocks 191 to enable the guide blocks 191 to slide up and down, the lower end of the guide blocks 191 is connected with the blocking plate 194, the plug 195 is provided with a plurality of water discharge holes 196 arranged on the top surface of the blocking plate 194 in a linear array manner and used for blocking the partition plate 9, and a plurality of return springs are connected between the blocking plate 194 and the partition plate 9;
step surfaces 198 are arranged at two ends of the partition plate 9 in the width direction, the two step surfaces 198 are arranged in a central symmetry manner, the positioning plate 193 is connected to the step surfaces 198 in a sliding manner by means of a sliding block on the positioning plate 193 and a sliding groove 1910 on the partition plate 9, the upper end surface of the positioning plate 193 is further connected with a hinge seat 1911, one end of the connecting rod 192 is hinged to the hinge seat 1911, and the other end of the connecting rod 192 is hinged to the guide block 191; the sliding groove 1910 at one end of the partition 9 in the width direction is a through sliding groove 1910, and the hinge seat 1911 at the through sliding groove 1910 is connected with the connecting rod 192.
The top of the guide block 191 is arc-shaped, the highest position of the guide block is also provided with a positioning groove 1912, the inner side of each side support 4 is provided with two positioning rods 17 matched with the positioning grooves 1912, the two positioning rods 17 are symmetrically arranged in the length direction of the side support 4, and the partition 9 is provided with a notch 199 for the positioning rods 17 to pass through.
In this embodiment, the rotating mechanism 5 includes a rotating motor 51, a first motor base 52, a first belt pulley 53 and a second belt pulley 54, the rotating motor 51 is installed outside the box 1 through the first motor base 52, an output end of the rotating motor 51 is connected to the first belt pulley 53, the first belt pulley 53 is connected to the second belt pulley 54 through a belt, and the second belt pulley 54 is installed on the rotating sleeve 8 on one side of the rotating motor 51.
In this embodiment, the power mechanism 6 includes a driving motor 61, a second motor base 62, a supporting base 63, a hydraulic cylinder 64, and a first friction disc 65, the driving motor 61 is slidably connected to the supporting base 63 through the second motor base 62, an outer end of the second motor base 62 is connected to an output end of the hydraulic cylinder 64, the hydraulic cylinder 64 is mounted on the supporting base 63 and is configured to achieve horizontal movement of the second motor base 62, the output end of the driving motor 61 penetrates through a side wall of the case 1 and is connected to the first friction disc 65, and an outer end of the driving shaft 7 is connected to the second friction. The connection between the output end of the driving motor 61 and the cabinet 1 needs to be sealed for water-proof to prevent the leakage of the washing water.
In this embodiment, an air inlet pipe 20 is provided on the sidewall of the box body 1 located in the drying chamber 10, the air inlet pipe 20 is connected to a dry air source, an air outlet 21 is provided on the box cover 2 for discharging moisture, and an inlet pipe 22 and a drain pipe 23 are provided on the sidewall of the box body 1 located in the cleaning process to realize the replacement of water in the cleaning chamber 11.
The working process and the principle of the cleaning and drying device are as follows:
under the operating condition, two wash cages 3 are located drying chamber 10 on upper portion and purge chamber 11 of lower part respectively, let in high temperature drying gas through intake pipe 20 in drying chamber 10, carry out drying process to the bulk drug in wasing cage 3, and the wash cage 3 that is located purge chamber 11 then washs the bulk drug with the help of the water in it. In the drying and cleaning processes, the cleaning cage 3 is in a self-rotating state. The principle is as follows: when the hydraulic cylinder 64 is extended, the first friction disc 65 is contacted with the second friction disc 66 and pressed (similar to the clutch principle), so that the power of the driving motor 61 can be transmitted to the cleaning cage 3. Conversely, the first friction disk 65 is separated from the second friction disk 66, and the cleaning cage 3 stops rotating.
When the cleaning and drying process is finished, the raw material medicine in the cleaning cage 3 positioned above is transferred away by utilizing suction equipment and is put into new uncleaned raw material medicine, in order to take and place materials conveniently, a feeding port with a cover plate is arranged on the side surface of the cleaning cage 3, and the cover plate is clamped in the feeding port;
then, the rotating motor 51 is started, and the side bracket 4 rotates the cleaning cage 3 by 180 degrees. In the process, the positioning rod 17 gradually approaches to and contacts with the guide block 191, due to the arc-shaped structural design of the top of the guide block 191, the positioning rod 17 presses the guide block 191 to force the guide block 191 to move downwards, meanwhile, the blocking plate 194 also moves downwards, the water discharge hole 196 is gradually opened, the connecting rod 192 also drives the positioning plate 193 to move towards the outer side of the width direction of the partition plate 9 along the step surface 198 at the moment, before the cleaning cage 3 is free from contact with the water baffle 15, the positioning plate 193 is located in the area where the step surface 198 is located, when the cleaning cage 3 is located at the vertical position, the positioning rod 17 is just clamped in the positioning groove 1912 at the top of the guide block 191 to complete the positioning of the side bracket 4, the water discharge hole 196 at the moment is also completely opened, and the positioning plate 193 also extends to the farthest end and stabilizes the water baffle. In this way, the switching of wash cage 3 between drying chamber 10 and wash chamber 11 is completed. When the positioning rod 17 is separated from the positioning groove 1912, the guide block 191 is lifted and returned by the return spring in the process, so that the other positioning rod 17 symmetrically arranged does not interfere with the blocking plate 194. In addition, the top surface of the partition 9 is provided with a curved surface depressed downward to facilitate the drainage of water falling on the partition 9.
It will be appreciated by those skilled in the art that the invention may be embodied in other specific forms without departing from the spirit or essential characteristics thereof. The embodiments disclosed above are therefore to be considered in all respects as illustrative and not restrictive. All changes which come within the scope of or equivalence to the invention are intended to be embraced therein.

Claims (9)

1. The traditional Chinese medicine compound mouthwash is characterized by being prepared from the following raw materials in parts by weight: 20-40 parts of wild chrysanthemum, 25-35 parts of golden cypress, 10-25 parts of honeysuckle, 30-40 parts of maimendong, 40-60 parts of lychee seed, 2-8 parts of mirabilis jalapa, 5-10 parts of chamomile, 10-15 parts of cortex meliae, 1-5 parts of preservative and 10-15 parts of sweetener.
2. The traditional Chinese medicine compound mouthwash according to claim 1, is prepared from the following raw materials in parts by weight: 30 parts of wild chrysanthemum flower, 30 parts of golden cypress, 20 parts of honeysuckle flower, 35 parts of maimendong, 50 parts of lychee seed, 5 parts of mirabilis jalapa, 8 parts of chamomile, 12 parts of cortex meliae, 3 parts of preservative and 12 parts of sweetener.
3. The traditional Chinese medicine compound mouthwash according to claim 1, wherein the sweetener is one or a mixture of several of stevia rebaudiana, xylitol, sorbitol and alitame mixed according to any ratio.
4. A method for preparing a compound traditional Chinese medicine mouthwash according to claim 1 or 2, which comprises the following steps:
(1) putting wild chrysanthemum flower, amur corktree bark, honeysuckle flower, maidenhair, lychee seed, mirabilis jalapa, chamomile and chinaberry bark in the raw material medicines into a cleaning and drying device according to the proportion for cleaning, then drying the raw material medicines by using the cleaning and drying device, pumping the dried raw material medicines into a crusher by using suction equipment, crushing the raw material medicines by using the crusher, and sieving the crushed raw material medicines by using a 105-fold 110-mesh sieve;
(2) adding deionized water into the crushed raw material medicines in the step (1), decocting for 10-25 minutes, filtering while hot, and adding a certain amount of deionized water into the filtrate;
(3) grinding the sweetening agent and the preservative into powder, adding the powder into the filtrate obtained in the step (2), heating in a water bath at 52-58 ℃, stirring for 1-2 hours, cooling, filtering, sterilizing and subpackaging to obtain the traditional Chinese medicine compound mouthwash.
5. The preparation method of the traditional Chinese medicine compound mouthwash according to claim 4, is characterized in that: the cleaning and drying device comprises a box body (1), a box cover (2), a cleaning cage (3), a side support (4), a rotating mechanism (5) and a power mechanism (6), wherein the box body (1) is of a shell structure with an upper end opening, the box cover (2) is installed at the top of the box body (1), the cleaning cage (3) is provided with two parts which are symmetrically installed at the upper end and the lower end of the side support (4), the cleaning cage (3) is rotationally connected onto the side support (4) through a driving shaft (7), when the cleaning cage (3) is in a vertical position, the driving shaft (7) can be connected with the power mechanism (6) to drive the cleaning cage (3) to rotate automatically, the outer side of the side support (4) is provided with a rotating sleeve (8), the rotating sleeve (8) is rotationally connected onto the side wall of the box body (1) through a bearing, the rotating sleeve (8) is further connected to the rotating mechanism (5) to, a partition plate (9) which is horizontally arranged is further arranged between the two side supports (4) and divides the box body (1) into a drying chamber (10) at the upper part and a cleaning chamber (11) at the lower part, two ends of the partition plate (9) are connected with support shafts (12), the support shafts (12) penetrate through holes in the side supports (4) and rotating sleeves (8), the outer ends of the support shafts (12) are connected with positioning shafts (13) with polygonal cross sections, a fixing plate (14) is installed on the outer side of the box body (1), and positioning holes matched with the positioning shafts (13) are formed in the fixing plate (14) and used for limiting the positioning shafts (13);
in box (1), lie in the width direction of baffle (9) and still the symmetry install two breakwaters (15), the one end of breakwater (15) is passed through pivot (16) and is rotated and connect on the inner wall of box (1), leave the clearance between the other end of breakwater (15) and baffle (9), pivot (16) pass the lateral wall of box (1) and the cover is equipped with torsional spring (17) and can keep the horizontality in order to realize breakwater (15), still install on baffle (9) and shelter from drainage mechanism (19), and be used for realizing that wash cage (3) can order about breakwater (15) steady when switching to vertical position, open wash port (196) on baffle (9) and realize the location of side branch frame (4).
6. The preparation method of the traditional Chinese medicine compound mouthwash according to claim 5, is characterized in that: the shielding and drainage mechanism (19) comprises two guide blocks (191), a connecting rod (192), a positioning plate (193), a blocking plate (194) and a plug (195), the two guide blocks (191) are symmetrically arranged at two ends of the length direction of the partition plate (9), a guide hole (197) matched with the guide blocks (191) is formed in the partition plate (9) to enable the guide blocks (191) to slide up and down, the blocking plate (194) is connected to the lower end of the guide blocks (191), the plug (195) is provided with a plurality of drainage holes (196) which are arranged on the top surface of the blocking plate (194) in a linear array mode and used for blocking the partition plate (9), and a plurality of reset springs are connected between the blocking plate (194) and the partition plate (9);
step surfaces (198) are arranged at two ends of the partition plate (9) in the width direction, the two step surfaces (198) are arranged in a central symmetry mode, the positioning plate (193) is connected to the step surfaces (198) in a sliding mode through a sliding block on the positioning plate (193) and a sliding groove (1910) on the partition plate (9), the upper end face of the positioning plate (193) is further connected with a hinge seat (1911), one end of the connecting rod (192) is hinged to the hinge seat (1911), and the other end of the connecting rod (192) is hinged to the guide block (191);
the top of the guide block (191) is arc-shaped, a positioning groove (1912) is further formed in the highest position of the guide block, two positioning rods (17) matched with the positioning grooves (1912) are arranged on the inner side of each side support (4), and the two positioning rods (17) are symmetrically arranged in the length direction of the side supports (4).
7. The preparation method of the traditional Chinese medicine compound mouthwash according to claim 6, is characterized in that: the rotating mechanism (5) comprises a rotating motor (51), a motor base I (52), a belt pulley I (53) and a belt pulley II (54), the rotating motor (51) is installed on the outer side of the box body (1) through the motor base I (52), the output end of the rotating motor (51) is connected to the belt pulley I (53), the belt pulley I (53) is connected to the belt pulley II (54) through a belt, and the belt pulley II (54) is installed on a rotating sleeve (8) located on one side of the rotating motor (51).
8. The preparation method of the traditional Chinese medicine compound mouthwash according to claim 7, is characterized in that: the power mechanism (6) comprises a driving motor (61), a second motor base (62), a supporting seat (63), a hydraulic cylinder (64) and a first friction disc (65), the driving motor (61) is connected to the supporting seat (63) in a sliding mode through the second motor base (62), the outer end of the second motor base (62) is connected to the output end of the hydraulic cylinder (64), the hydraulic cylinder (64) is installed on the supporting seat (63) and used for achieving horizontal movement of the second motor base (62), the output end of the driving motor (61) penetrates through the side wall of the box body (1) and is connected to the first friction disc (65), and the outer end of the driving shaft (7) is connected with the second friction disc (.
9. The preparation method of the compound traditional Chinese medicine mouthwash according to claim 8, is characterized in that: be equipped with intake pipe (20) on box (1) lateral wall that is located drying chamber (10), be equipped with gas vent (21) on case lid (2), be equipped with inlet tube (22) and drain pipe (23) on the lateral wall of box (1) that is located when wasing.
CN202010660550.1A 2020-07-10 2020-07-10 Traditional Chinese medicine compound gargle and preparation method thereof Pending CN111743844A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202010660550.1A CN111743844A (en) 2020-07-10 2020-07-10 Traditional Chinese medicine compound gargle and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202010660550.1A CN111743844A (en) 2020-07-10 2020-07-10 Traditional Chinese medicine compound gargle and preparation method thereof

Publications (1)

Publication Number Publication Date
CN111743844A true CN111743844A (en) 2020-10-09

Family

ID=72711074

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202010660550.1A Pending CN111743844A (en) 2020-07-10 2020-07-10 Traditional Chinese medicine compound gargle and preparation method thereof

Country Status (1)

Country Link
CN (1) CN111743844A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113476386A (en) * 2021-08-19 2021-10-08 杭州迅腾医疗器械有限公司 Gargle and preparation method thereof
CN114642616A (en) * 2022-01-17 2022-06-21 西南大学 Mouth wash based on mulberry leaf polyphenol and preparation method thereof
CN114754438A (en) * 2022-03-04 2022-07-15 湖北天兴瑞智能科技有限公司 Traditional Chinese medicine health-preserving purifier and traditional Chinese medicine refining method

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101040830A (en) * 2006-03-23 2007-09-26 吴志坚 Chinese traditional medicine tea bag for gargling
CN103536497A (en) * 2013-10-30 2014-01-29 昆明理工大学 Traditional Chinese medicinal compound collutory and preparation method thereof
CN104414886A (en) * 2013-08-21 2015-03-18 左华炜 Mouthwash
CN105689320A (en) * 2016-02-04 2016-06-22 王祥领 Traditional Chinese medicine cleaning and drying device
CN105920210A (en) * 2016-06-20 2016-09-07 徐艳 Mouthwash for mouth care of cancer patients receiving chemotherapy
CN105999241A (en) * 2016-06-21 2016-10-12 江苏奇力康皮肤药业有限公司 Compound gargle for preventing and treating periodontosis and preparation method thereof
CN106607359A (en) * 2016-12-28 2017-05-03 郑州吉音动漫科技有限公司 A traditional Chinese medicinal material cleaning, drying and screening device
CN106623198A (en) * 2016-12-29 2017-05-10 河南时代云通信技术有限公司 Water-saving traditional Chinese medicine cleaning and drying device
CN107166922A (en) * 2017-07-07 2017-09-15 张艳艳 A kind of Chinese medicine Rapid Cleaning drying device

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101040830A (en) * 2006-03-23 2007-09-26 吴志坚 Chinese traditional medicine tea bag for gargling
CN104414886A (en) * 2013-08-21 2015-03-18 左华炜 Mouthwash
CN103536497A (en) * 2013-10-30 2014-01-29 昆明理工大学 Traditional Chinese medicinal compound collutory and preparation method thereof
CN105689320A (en) * 2016-02-04 2016-06-22 王祥领 Traditional Chinese medicine cleaning and drying device
CN105920210A (en) * 2016-06-20 2016-09-07 徐艳 Mouthwash for mouth care of cancer patients receiving chemotherapy
CN105999241A (en) * 2016-06-21 2016-10-12 江苏奇力康皮肤药业有限公司 Compound gargle for preventing and treating periodontosis and preparation method thereof
CN106607359A (en) * 2016-12-28 2017-05-03 郑州吉音动漫科技有限公司 A traditional Chinese medicinal material cleaning, drying and screening device
CN106623198A (en) * 2016-12-29 2017-05-10 河南时代云通信技术有限公司 Water-saving traditional Chinese medicine cleaning and drying device
CN107166922A (en) * 2017-07-07 2017-09-15 张艳艳 A kind of Chinese medicine Rapid Cleaning drying device

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
季红玲: "急性口腔黏膜炎31例中药护理效果观察", 《中医药导报》 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113476386A (en) * 2021-08-19 2021-10-08 杭州迅腾医疗器械有限公司 Gargle and preparation method thereof
CN114642616A (en) * 2022-01-17 2022-06-21 西南大学 Mouth wash based on mulberry leaf polyphenol and preparation method thereof
CN114642616B (en) * 2022-01-17 2024-01-26 西南大学 Mulberry leaf polyphenol-based mouthwash and preparation method thereof
CN114754438A (en) * 2022-03-04 2022-07-15 湖北天兴瑞智能科技有限公司 Traditional Chinese medicine health-preserving purifier and traditional Chinese medicine refining method
CN114754438B (en) * 2022-03-04 2024-04-16 湖北天兴瑞智能科技有限公司 Traditional Chinese medicine health preserving purifier and traditional Chinese medicine refining method

Similar Documents

Publication Publication Date Title
CN111743844A (en) Traditional Chinese medicine compound gargle and preparation method thereof
Prakash et al. Role of Triphala in dentistry
CN108606939A (en) A kind of composition and its application and preparation method with oral health function
CN110787243A (en) Chinese herbal medicine dressing for wound treatment and preparation method thereof
CN103520049B (en) Compound Chinese medicine extract is preparing the application in oral cavity nursing health products
CN207655583U (en) A kind of medical instrument cleaning sterilizing device
CN102151241A (en) Toothpaste containing natural plant extractive and preparation method thereof
CN108464956A (en) A kind of composition and the preparation method and application thereof applied to oral cavity
CN109223663A (en) A kind of Chinese herbal toothpaste and preparation method thereof for gingivitis
CN205413706U (en) Washing and drying device of apparatus is washd by gynaecology
CN107412131A (en) Oral nursing liquid and Pediatric Oral Emergency maintenance method
CN106377481A (en) Extraction method of cyperus rotundus extract and toothpaste and mouth wash containing cyperus rotundus extract
CN1234389C (en) Chinese traditional medicine for treating oral disease and its preparing process
CN106858028B (en) Chewing gum containing eclipta and preparation method thereof
CN105287244A (en) Montmorillonite-containing functional toothpaste and preparation method thereof
CN1229104C (en) Composition for preventing and curing gingivitis
CN107913234A (en) A kind of savatier monochasma herb toothpaste and preparation method thereof
CN211497276U (en) Goat farm sewage treatment plant
CN1943625B (en) Oral sterilizing liquid
CN211052122U (en) Paediatrics respiratory tube belt cleaning device with stoving effect
CN110123723A (en) A kind of Garbo fruit blade mouthwash of pre- antiplaque and preparation method thereof
CN115463072B (en) Toothpaste and preparation method thereof
CN111297737A (en) A Chinese medicinal facial mask containing Sargassum extract for promoting blood circulation and resisting aging, and its preparation method
CN112022775A (en) Oral care product for resisting helicobacter pylori
CN217016548U (en) Preparation facilities of antibacterial gel of aloe nursing

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20201009