CN111732672A - 一种具有降尿酸功效的黄秋葵聚半乳糖醛酸及其制备方法和用途 - Google Patents
一种具有降尿酸功效的黄秋葵聚半乳糖醛酸及其制备方法和用途 Download PDFInfo
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- CN111732672A CN111732672A CN202010709763.9A CN202010709763A CN111732672A CN 111732672 A CN111732672 A CN 111732672A CN 202010709763 A CN202010709763 A CN 202010709763A CN 111732672 A CN111732672 A CN 111732672A
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- okra
- polygalacturonic acid
- nacl
- leaching
- acid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0045—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Galacturonans, e.g. methyl ester of (alpha-1,4)-linked D-galacturonic acid units, i.e. pectin, or hydrolysis product of methyl ester of alpha-1,4-linked D-galacturonic acid units, i.e. pectinic acid; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0045—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Galacturonans, e.g. methyl ester of (alpha-1,4)-linked D-galacturonic acid units, i.e. pectin, or hydrolysis product of methyl ester of alpha-1,4-linked D-galacturonic acid units, i.e. pectinic acid; Derivatives thereof
- C08B37/0048—Processes of extraction from organic materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Polymers & Plastics (AREA)
- Materials Engineering (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Description
Claims (10)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202010709763.9A CN111732672B (zh) | 2020-07-22 | 2020-07-22 | 一种具有降尿酸功效的黄秋葵聚半乳糖醛酸及其制备方法和用途 |
US17/138,926 US11479616B2 (en) | 2020-07-22 | 2020-12-31 | Method for preparing okra polygalacturonic acid having uric acid-lowering effect |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202010709763.9A CN111732672B (zh) | 2020-07-22 | 2020-07-22 | 一种具有降尿酸功效的黄秋葵聚半乳糖醛酸及其制备方法和用途 |
Publications (2)
Publication Number | Publication Date |
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CN111732672A true CN111732672A (zh) | 2020-10-02 |
CN111732672B CN111732672B (zh) | 2020-12-18 |
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Family Applications (1)
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CN202010709763.9A Active CN111732672B (zh) | 2020-07-22 | 2020-07-22 | 一种具有降尿酸功效的黄秋葵聚半乳糖醛酸及其制备方法和用途 |
Country Status (2)
Country | Link |
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US (1) | US11479616B2 (zh) |
CN (1) | CN111732672B (zh) |
Citations (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060233898A1 (en) * | 2004-10-26 | 2006-10-19 | Miri Seiberg | Ingestible compositions containing extracts |
US20090170809A1 (en) * | 2006-05-10 | 2009-07-02 | Bohus Biotech Ab | Pectic Polysaccharides Isolated from Fruit Pods of Okra |
CN102670673A (zh) * | 2012-05-21 | 2012-09-19 | 信毅投资咨询(上海)有限公司 | 秋葵活性成分在制备防治代谢性疾病的药物中的应用 |
CN104448033A (zh) * | 2014-12-31 | 2015-03-25 | 天津国际生物医药联合研究院 | 一种秋葵果胶的提取方法 |
CN104644528A (zh) * | 2015-03-13 | 2015-05-27 | 吉林工商学院 | 一种可食用的新型保湿营养软膏的制备及应用 |
US20150144574A1 (en) * | 2013-11-27 | 2015-05-28 | The Texas A&M University System | Polysaccharide agents and methods of their use for removing solids from water |
CN105218697A (zh) * | 2015-11-13 | 2016-01-06 | 谢镜国 | 一种从黄秋葵中提取秋葵多糖的方法 |
CN106496353A (zh) * | 2016-10-11 | 2017-03-15 | 芜湖职业技术学院 | 一种具有高清除胆固醇活性的黄秋葵果胶多糖制备方法 |
CN108703930A (zh) * | 2018-08-26 | 2018-10-26 | 福建乐伴护理用品有限公司 | 一种含有黄秋葵提取物的保湿霜及其制备方法 |
CN110463755A (zh) * | 2019-08-28 | 2019-11-19 | 广东省生物工程研究所(广州甘蔗糖业研究所) | 一种水果抗皱剂及其制备方法与应用 |
CN110916198A (zh) * | 2019-12-24 | 2020-03-27 | 集美大学 | 一种利用黄秋葵发酵酒酒渣同时制备果胶多糖和黏性糖蛋白的方法 |
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2020
- 2020-07-22 CN CN202010709763.9A patent/CN111732672B/zh active Active
- 2020-12-31 US US17/138,926 patent/US11479616B2/en active Active
Patent Citations (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060233898A1 (en) * | 2004-10-26 | 2006-10-19 | Miri Seiberg | Ingestible compositions containing extracts |
US20090170809A1 (en) * | 2006-05-10 | 2009-07-02 | Bohus Biotech Ab | Pectic Polysaccharides Isolated from Fruit Pods of Okra |
CN102670673A (zh) * | 2012-05-21 | 2012-09-19 | 信毅投资咨询(上海)有限公司 | 秋葵活性成分在制备防治代谢性疾病的药物中的应用 |
US20150144574A1 (en) * | 2013-11-27 | 2015-05-28 | The Texas A&M University System | Polysaccharide agents and methods of their use for removing solids from water |
CN104448033A (zh) * | 2014-12-31 | 2015-03-25 | 天津国际生物医药联合研究院 | 一种秋葵果胶的提取方法 |
CN104644528A (zh) * | 2015-03-13 | 2015-05-27 | 吉林工商学院 | 一种可食用的新型保湿营养软膏的制备及应用 |
CN105218697A (zh) * | 2015-11-13 | 2016-01-06 | 谢镜国 | 一种从黄秋葵中提取秋葵多糖的方法 |
CN106496353A (zh) * | 2016-10-11 | 2017-03-15 | 芜湖职业技术学院 | 一种具有高清除胆固醇活性的黄秋葵果胶多糖制备方法 |
CN108703930A (zh) * | 2018-08-26 | 2018-10-26 | 福建乐伴护理用品有限公司 | 一种含有黄秋葵提取物的保湿霜及其制备方法 |
CN110463755A (zh) * | 2019-08-28 | 2019-11-19 | 广东省生物工程研究所(广州甘蔗糖业研究所) | 一种水果抗皱剂及其制备方法与应用 |
CN110916198A (zh) * | 2019-12-24 | 2020-03-27 | 集美大学 | 一种利用黄秋葵发酵酒酒渣同时制备果胶多糖和黏性糖蛋白的方法 |
Non-Patent Citations (9)
Title |
---|
GAO HAN ET AL.: ""Purification, characterization and anti-fatigue activity of polysaccharide fractions from okra (Abelmoschus esculentus (L.) Moench)"", 《FOOD & FUNCTION》 * |
JING CHEN: ""Effect of okra polysaccharide on the spermatogenesis of KKAy mice"", 《INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES》 * |
TAO ZHANG ET AL.: ""Preliminary characterization and anti-hyperglycemic activity of a pectic polysaccharide from okra (Abelmoschus esculentus (L.) Moench)"", 《JOURNAL OF FUNCTIONAL FOODS》 * |
宋春蕾等: ""黄秋葵水提物对2型糖尿病大鼠血尿酸及肾功能的影响"", 《食品工业科技》 * |
张力田: "《碳水化合物化学(第1版)》", 31 October 1988, 轻工业出版社 * |
张灵敏: ""黄秋葵水提物对实验性2型糖尿病大鼠血糖、血脂及血尿酸水平的影响"", 《中国优秀硕士学位论文全文数据库 医药卫生科技辑》 * |
李明主编: "《提取技术与实例(第1版)》", 30 September 2006, 化学工业出版社 * |
王建蕊: ""黄秋葵功能成分提取及应用研究"", 《中国优秀硕士学位论文全文数据库工程科技I辑》 * |
董雨晴等: ""黄秋葵多糖提取条件优化及多糖纯度检测"", 《食品工业》 * |
Also Published As
Publication number | Publication date |
---|---|
US11479616B2 (en) | 2022-10-25 |
CN111732672B (zh) | 2020-12-18 |
US20220025074A1 (en) | 2022-01-27 |
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Address after: No.10, shiliugang Road, Haizhu District, Guangzhou City, Guangdong Province 510000 Patentee after: Institute of biological and medical engineering, Guangdong Academy of Sciences Address before: No.10, shiliugang Road, Haizhu District, Guangzhou City, Guangdong Province 510000 Patentee before: Institute of bioengineering, Guangdong Academy of Sciences |
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Address after: No.10, shiliugang Road, Haizhu District, Guangzhou City, Guangdong Province 510000 Patentee after: Institute of bioengineering, Guangdong Academy of Sciences Address before: No. 10, shiliugang Road, Haizhu District, Guangzhou, Guangdong 510310 Patentee before: GUANGDONG PROVINCIAL BIOENGINEERING INSTITUTE (GUANGZHOU SUGARCANE INDUSTRY RESEARCH INSTITUTE) |