CN111714393A - Skin activating composition and activating emulsion thereof - Google Patents
Skin activating composition and activating emulsion thereof Download PDFInfo
- Publication number
- CN111714393A CN111714393A CN202010586694.7A CN202010586694A CN111714393A CN 111714393 A CN111714393 A CN 111714393A CN 202010586694 A CN202010586694 A CN 202010586694A CN 111714393 A CN111714393 A CN 111714393A
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- CN
- China
- Prior art keywords
- component
- skin
- parts
- dipropylene glycol
- emulsion
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- Pending
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- 239000000203 mixture Substances 0.000 title claims abstract description 34
- 239000000839 emulsion Substances 0.000 title claims abstract description 33
- 230000003213 activating effect Effects 0.000 title claims abstract description 17
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 claims abstract description 34
- 239000000047 product Substances 0.000 claims abstract description 20
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 claims abstract description 17
- 229960000458 allantoin Drugs 0.000 claims abstract description 17
- WTVHAMTYZJGJLJ-UHFFFAOYSA-N (+)-(4S,8R)-8-epi-beta-bisabolol Natural products CC(C)=CCCC(C)C1(O)CCC(C)=CC1 WTVHAMTYZJGJLJ-UHFFFAOYSA-N 0.000 claims abstract description 16
- RGZSQWQPBWRIAQ-CABCVRRESA-N (-)-alpha-Bisabolol Chemical compound CC(C)=CCC[C@](C)(O)[C@H]1CCC(C)=CC1 RGZSQWQPBWRIAQ-CABCVRRESA-N 0.000 claims abstract description 16
- FYGDTMLNYKFZSV-URKRLVJHSA-N (2s,3r,4s,5s,6r)-2-[(2r,4r,5r,6s)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2r,4r,5r,6s)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1[C@@H](CO)O[C@@H](OC2[C@H](O[C@H](O)[C@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O FYGDTMLNYKFZSV-URKRLVJHSA-N 0.000 claims abstract description 16
- 229920002498 Beta-glucan Polymers 0.000 claims abstract description 16
- 241000219357 Cactaceae Species 0.000 claims abstract description 16
- 241000186660 Lactobacillus Species 0.000 claims abstract description 16
- RGZSQWQPBWRIAQ-LSDHHAIUSA-N alpha-Bisabolol Natural products CC(C)=CCC[C@@](C)(O)[C@@H]1CCC(C)=CC1 RGZSQWQPBWRIAQ-LSDHHAIUSA-N 0.000 claims abstract description 16
- 229940036350 bisabolol Drugs 0.000 claims abstract description 16
- HHGZABIIYIWLGA-UHFFFAOYSA-N bisabolol Natural products CC1CCC(C(C)(O)CCC=C(C)C)CC1 HHGZABIIYIWLGA-UHFFFAOYSA-N 0.000 claims abstract description 16
- 238000000855 fermentation Methods 0.000 claims abstract description 16
- 230000004151 fermentation Effects 0.000 claims abstract description 16
- 229940039696 lactobacillus Drugs 0.000 claims abstract description 16
- 244000068988 Glycine max Species 0.000 claims abstract description 15
- 235000010469 Glycine max Nutrition 0.000 claims abstract description 15
- 239000000706 filtrate Substances 0.000 claims abstract description 15
- 235000013336 milk Nutrition 0.000 claims abstract description 15
- 239000008267 milk Substances 0.000 claims abstract description 15
- 210000004080 milk Anatomy 0.000 claims abstract description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 10
- 230000004913 activation Effects 0.000 claims abstract description 9
- 230000001804 emulsifying effect Effects 0.000 claims abstract description 6
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 66
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 36
- SZXQTJUDPRGNJN-UHFFFAOYSA-N dipropylene glycol Chemical compound OCCCOCCCO SZXQTJUDPRGNJN-UHFFFAOYSA-N 0.000 claims description 36
- -1 polydimethylsiloxane Polymers 0.000 claims description 30
- 239000002562 thickening agent Substances 0.000 claims description 30
- XDOFQFKRPWOURC-UHFFFAOYSA-N 16-methylheptadecanoic acid Chemical compound CC(C)CCCCCCCCCCCCCCC(O)=O XDOFQFKRPWOURC-UHFFFAOYSA-N 0.000 claims description 24
- 229920006037 cross link polymer Polymers 0.000 claims description 24
- 239000004205 dimethyl polysiloxane Substances 0.000 claims description 24
- 235000013870 dimethyl polysiloxane Nutrition 0.000 claims description 24
- 235000011187 glycerol Nutrition 0.000 claims description 24
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims description 24
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 claims description 24
- 229920001577 copolymer Polymers 0.000 claims description 22
- BANXPJUEBPWEOT-UHFFFAOYSA-N 2-methyl-Pentadecane Chemical compound CCCCCCCCCCCCCC(C)C BANXPJUEBPWEOT-UHFFFAOYSA-N 0.000 claims description 20
- 238000010438 heat treatment Methods 0.000 claims description 15
- KZRXPHCVIMWWDS-AWEZNQCLSA-N (4S)-4-amino-5-dodecanoyloxy-5-oxopentanoic acid Chemical compound CCCCCCCCCCCC(=O)OC(=O)[C@@H](N)CCC(O)=O KZRXPHCVIMWWDS-AWEZNQCLSA-N 0.000 claims description 12
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims description 12
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 12
- LEACJMVNYZDSKR-UHFFFAOYSA-N 2-octyldodecan-1-ol Chemical compound CCCCCCCCCCC(CO)CCCCCCCC LEACJMVNYZDSKR-UHFFFAOYSA-N 0.000 claims description 12
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 claims description 12
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 claims description 12
- 229920002126 Acrylic acid copolymer Polymers 0.000 claims description 12
- SNPLKNRPJHDVJA-ZETCQYMHSA-N D-panthenol Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCCO SNPLKNRPJHDVJA-ZETCQYMHSA-N 0.000 claims description 12
- 240000007817 Olea europaea Species 0.000 claims description 12
- 239000004264 Petrolatum Substances 0.000 claims description 12
- 229920002385 Sodium hyaluronate Polymers 0.000 claims description 12
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims description 12
- 229940048053 acrylate Drugs 0.000 claims description 12
- BTFJIXJJCSYFAL-UHFFFAOYSA-N arachidyl alcohol Natural products CCCCCCCCCCCCCCCCCCCCO BTFJIXJJCSYFAL-UHFFFAOYSA-N 0.000 claims description 12
- 150000002148 esters Chemical class 0.000 claims description 12
- 229940071085 lauroyl glutamate Drugs 0.000 claims description 12
- 238000002156 mixing Methods 0.000 claims description 12
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 claims description 12
- AEIJTFQOBWATKX-UHFFFAOYSA-N octane-1,2-diol Chemical compound CCCCCCC(O)CO AEIJTFQOBWATKX-UHFFFAOYSA-N 0.000 claims description 12
- 229940101267 panthenol Drugs 0.000 claims description 12
- 235000020957 pantothenol Nutrition 0.000 claims description 12
- 239000011619 pantothenol Substances 0.000 claims description 12
- 229940023750 peg-60 glyceryl isostearate Drugs 0.000 claims description 12
- 229940066842 petrolatum Drugs 0.000 claims description 12
- 235000019271 petrolatum Nutrition 0.000 claims description 12
- 229960005323 phenoxyethanol Drugs 0.000 claims description 12
- 229920001495 poly(sodium acrylate) polymer Polymers 0.000 claims description 12
- 229940010747 sodium hyaluronate Drugs 0.000 claims description 12
- NNMHYFLPFNGQFZ-UHFFFAOYSA-M sodium polyacrylate Chemical compound [Na+].[O-]C(=O)C=C NNMHYFLPFNGQFZ-UHFFFAOYSA-M 0.000 claims description 12
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims description 12
- 229940032094 squalane Drugs 0.000 claims description 12
- GYDJEQRTZSCIOI-LJGSYFOKSA-N tranexamic acid Chemical compound NC[C@H]1CC[C@H](C(O)=O)CC1 GYDJEQRTZSCIOI-LJGSYFOKSA-N 0.000 claims description 12
- 229960000401 tranexamic acid Drugs 0.000 claims description 12
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 claims description 12
- 229920002554 vinyl polymer Polymers 0.000 claims description 12
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 claims description 11
- PQUXFUBNSYCQAL-UHFFFAOYSA-N 1-(2,3-difluorophenyl)ethanone Chemical group CC(=O)C1=CC=CC(F)=C1F PQUXFUBNSYCQAL-UHFFFAOYSA-N 0.000 claims description 10
- 229940043268 2,2,4,4,6,8,8-heptamethylnonane Drugs 0.000 claims description 10
- BQMNFPBUAQPINY-UHFFFAOYSA-N azane;2-methyl-2-(prop-2-enoylamino)propane-1-sulfonic acid Chemical compound [NH4+].[O-]S(=O)(=O)CC(C)(C)NC(=O)C=C BQMNFPBUAQPINY-UHFFFAOYSA-N 0.000 claims description 10
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims description 10
- KUVMKLCGXIYSNH-UHFFFAOYSA-N isopentadecane Natural products CCCCCCCCCCCCC(C)C KUVMKLCGXIYSNH-UHFFFAOYSA-N 0.000 claims description 10
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 claims description 10
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 claims description 10
- 229940068968 polysorbate 80 Drugs 0.000 claims description 10
- 229920000053 polysorbate 80 Polymers 0.000 claims description 10
- 238000002360 preparation method Methods 0.000 claims description 10
- 229940047670 sodium acrylate Drugs 0.000 claims description 10
- 238000003756 stirring Methods 0.000 claims description 8
- 239000003086 colorant Substances 0.000 claims description 6
- 238000001816 cooling Methods 0.000 claims description 6
- 239000003906 humectant Substances 0.000 claims description 5
- 229940008099 dimethicone Drugs 0.000 claims description 4
- 239000003974 emollient agent Substances 0.000 claims description 4
- GHJOIQFPDMIKHT-UHFFFAOYSA-N propane-1,2,3-triol;prop-2-enoic acid Chemical compound OC(=O)C=C.OCC(O)CO GHJOIQFPDMIKHT-UHFFFAOYSA-N 0.000 claims description 4
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 claims description 2
- GEOVAQINSQDMCB-UHFFFAOYSA-N C(CCCCCCC)(=O)O.C(CC)OC(CCCCCC)=O Chemical compound C(CCCCCCC)(=O)O.C(CC)OC(CCCCCC)=O GEOVAQINSQDMCB-UHFFFAOYSA-N 0.000 claims description 2
- 239000004902 Softening Agent Substances 0.000 claims description 2
- 238000000034 method Methods 0.000 claims description 2
- 238000005303 weighing Methods 0.000 claims description 2
- 239000004909 Moisturizer Substances 0.000 claims 1
- 239000006071 cream Substances 0.000 claims 1
- 230000001333 moisturizer Effects 0.000 claims 1
- 150000003626 triacylglycerols Chemical class 0.000 claims 1
- 239000002537 cosmetic Substances 0.000 abstract description 34
- 230000003020 moisturizing effect Effects 0.000 abstract description 17
- 230000037303 wrinkles Effects 0.000 abstract description 10
- 230000006870 function Effects 0.000 abstract description 3
- 239000004480 active ingredient Substances 0.000 abstract description 2
- 230000008719 thickening Effects 0.000 abstract description 2
- 239000004615 ingredient Substances 0.000 abstract 2
- 210000003491 skin Anatomy 0.000 description 38
- 230000000052 comparative effect Effects 0.000 description 15
- 230000018109 developmental process Effects 0.000 description 12
- 238000011161 development Methods 0.000 description 11
- OWPUOLBODXJOKH-UHFFFAOYSA-N 2,3-dihydroxypropyl prop-2-enoate Chemical compound OCC(O)COC(=O)C=C OWPUOLBODXJOKH-UHFFFAOYSA-N 0.000 description 8
- 230000000694 effects Effects 0.000 description 6
- 239000002994 raw material Substances 0.000 description 6
- 239000000126 substance Substances 0.000 description 4
- 230000006872 improvement Effects 0.000 description 3
- 210000003205 muscle Anatomy 0.000 description 3
- 210000000434 stratum corneum Anatomy 0.000 description 3
- 206010013786 Dry skin Diseases 0.000 description 2
- 150000001720 carbohydrates Chemical class 0.000 description 2
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 230000035876 healing Effects 0.000 description 2
- 230000014759 maintenance of location Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 235000015097 nutrients Nutrition 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 230000008439 repair process Effects 0.000 description 2
- 238000006467 substitution reaction Methods 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 206010003694 Atrophy Diseases 0.000 description 1
- 208000032544 Cicatrix Diseases 0.000 description 1
- 229920000832 Cutin Polymers 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 208000028990 Skin injury Diseases 0.000 description 1
- 206010052428 Wound Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000001133 acceleration Effects 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000037444 atrophy Effects 0.000 description 1
- 230000003385 bacteriostatic effect Effects 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000003796 beauty Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000010261 cell growth Effects 0.000 description 1
- 230000019522 cellular metabolic process Effects 0.000 description 1
- 239000003599 detergent Substances 0.000 description 1
- 230000037336 dry skin Effects 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 210000004177 elastic tissue Anatomy 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 230000001815 facial effect Effects 0.000 description 1
- 238000007429 general method Methods 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 230000000887 hydrating effect Effects 0.000 description 1
- 239000002085 irritant Substances 0.000 description 1
- 231100000021 irritant Toxicity 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 239000002932 luster Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- YLGYACDQVQQZSW-UHFFFAOYSA-N n,n-dimethylprop-2-enamide Chemical compound CN(C)C(=O)C=C YLGYACDQVQQZSW-UHFFFAOYSA-N 0.000 description 1
- 230000037311 normal skin Effects 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 206010033675 panniculitis Diseases 0.000 description 1
- 239000012466 permeate Substances 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 238000007788 roughening Methods 0.000 description 1
- 231100000241 scar Toxicity 0.000 description 1
- 230000037387 scars Effects 0.000 description 1
- 230000009759 skin aging Effects 0.000 description 1
- 206010040872 skin infection Diseases 0.000 description 1
- 230000036548 skin texture Effects 0.000 description 1
- 150000003384 small molecules Chemical class 0.000 description 1
- FWFUWXVFYKCSQA-UHFFFAOYSA-M sodium;2-methyl-2-(prop-2-enoylamino)propane-1-sulfonate Chemical compound [Na+].[O-]S(=O)(=O)CC(C)(C)NC(=O)C=C FWFUWXVFYKCSQA-UHFFFAOYSA-M 0.000 description 1
- 230000003238 somatosensory effect Effects 0.000 description 1
- 235000013322 soy milk Nutrition 0.000 description 1
- 210000004304 subcutaneous tissue Anatomy 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 229940104261 taurate Drugs 0.000 description 1
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 230000007306 turnover Effects 0.000 description 1
- 230000002087 whitening effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Emergency Medicine (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a skin activation composition and an activation emulsion thereof. The skin activating composition contains various active ingredients such as allantoin, bisabolol, cactus extract, beta-glucan, bioglycan-1, lactobacillus/soybean milk fermentation product filtrate and the like, and is matched with the ingredients with moisturizing, thickening and emulsifying functions in a specific combination, and the ingredients are mutually synergistically activated and synergized, so that the cosmetics prepared based on the skin activating composition have excellent skin activating effect, and meanwhile, the problems of skin wrinkles, water wettability, roughness and uniformity can be effectively improved.
Description
Technical Field
The invention relates to the field of cosmetics, and particularly relates to a skin activation composition and an activation emulsion thereof.
Background
Cosmetics (or color cosmetics) are currently substances used to enhance the beauty of the human body in addition to simple cleansing products, and are primarily intended for topical application to the skin to provide anti-aging, hydrating and/or skin texture activating effects.
As the human skin can age, have rough skin or generate wrinkles and other phenomena along with age, physiological factors or environmental factors, for example, the skin of normal young people has certain elasticity and tension, and when the expression muscle is relaxed, the skin can be quickly recovered, so that the wrinkles disappear. But in the middle age, the skin begins to age obviously, becomes thin, hard, dry and has reduced tension; the dermal elastic fibers are denatured and broken, and the tension and elasticity of the skin are reduced. Thus, when the expression muscle is relaxed, the skin does not recover very quickly, and wrinkles are formed over time. Furthermore, with age, the skin and subcutaneous tissue become more lax, and with the atrophy or loss of facial support tissue and the laxity of muscles, the skin slips under the force of gravity, forming deeper wrinkles. The rough skin is a skin trouble caused by external factors such as dryness, ultraviolet rays, irritants such as detergents and chemicals, or internal factors such as disturbance of hormone balance, and is accompanied by phenomena such as reduction of barrier function of stratum corneum, reduction of water content of stratum corneum, acceleration of epidermal turnover, and roughening of cutin due to generation of scales. Therefore, if the cells on the skin lose their elasticity and moisture-retaining function, they may cause wrinkles, dryness and loss of luster.
Various functional cosmetics which are greatly publicized in the market at present have not very obvious actual efficacy on the aspects of improving dry skin, peeling, wrinkles, brightness, elasticity and the like, and some functional cosmetics have irritation to the skin and are easy to cause allergy. Moreover, most of the cosmetics have single efficacy in terms of components of various commercially available cosmetics, and the traditional cosmetics only supply external nutrition to the skin and cover aged skin, so that the skin aging cannot be prevented. The actual effect of the nutrient and active cosmetic prepared by the general method is not great, because the nutrient and active cosmetic are not easy to permeate into the deep layer of the skin, normal skin can only absorb a few of small molecules and fat-soluble substances, macromolecular proteins cannot be absorbed and are more difficult to enter cells, the active cosmetic is easy to be influenced by external conditions and is often inactivated in use, and as the cosmetic is accepted and used by more and more women, the new application of the cosmetic is continuously developed to become a new trend of the cosmetic development.
Therefore, the traditional skin-activating skin care products can not meet the actual demands, and a cosmetic which can effectively improve the problems and has the efficacy of water retention or moisture retention and extremely high market value is needed.
Disclosure of Invention
It is an object of the present invention to provide a skin-activating composition;
it is another object of the present invention to provide an activated emulsion;
another object of the present invention is to provide a method for preparing the above activated emulsion.
The technical scheme adopted by the invention is as follows:
in a first aspect of the present invention, there is provided:
a skin activating composition comprising the following components:
and (2) component A: PEG-60 glyceryl isostearate and emollient;
and (B) component: phytosterol/octyldodecanol lauroyl glutamate, dimethicone/vinyl dimethicone crosspolymer, isostearic acid, essence, olive squalane;
and (3) component C: humectant, phenoxyethanol, caprylyl glycol, allantoin, tranexamic acid, colorant;
and (3) component D: thickener A, sodium polyacrylate, glycerin acrylate/acrylic acid copolymer, dipropylene glycol and glycerin;
and (3) component E: triethanolamine, bisabolol, a thickening agent B, cactus extract, beta-glucan, bioglycan-1, lactobacillus/soybean milk fermentation product filtrate, sodium hyaluronate and dipropylene glycol.
The allantoin can promote the growth and metabolism of cells, effectively soften the stratum corneum protein, accelerate the healing of wounds and effectively treat skin injury or infection. In addition, allantoin has skin moisturizing, repairing and moisturizing effects.
The bisabolol of the present invention has anti-inflammatory properties and also has been demonstrated to have bacteriostatic activity.
The cactus extractive solution can promote the regeneration and repair of cells and restore the elasticity of skin.
The beta-glucan in the invention can help to renew and repair tense skin, effectively reduce skin wrinkles, improve the moisture retention and tightening smoothness of the skin, and promote the healing of scars.
The biological carbohydrate gum-1 has the effects of moisturizing, improving skin feel, relieving skin and bringing soft, silky and pleasant skin feel to the skin.
The lactobacillus/soybean milk fermentation product filtrate has the effects of protection, relieving, moisturizing, repairing and whitening.
Further, the skin activation composition comprises the following components in parts by mass:
and (2) component A: 0.1-0.5 part of PEG-60 glyceryl isostearate and 2.1-6.5 parts of a softening agent;
and (B) component: 0.1-0.5 part of phytosterol/octyldodecanol lauroyl glutamate, 3-5 parts of polydimethylsiloxane/vinyl polydimethylsiloxane cross-linked polymer, 0.1-0.5 part of isostearic acid, 0.01-0.08 part of essence and 0.1-0.5 part of olive squalane;
and (3) component C: 5.5 to 9.6 parts of humectant, 0.1 to 0.4 part of phenoxyethanol, 0.1 to 0.2 part of caprylyl glycol, 0.1 to 0.2 part of allantoin, 0.1 to 0.2 part of tranexamic acid and 0.1 to 0.2 part of colorant;
and (3) component D: 0.18-0.38 part of thickener A, 0.1-0.2 part of sodium polyacrylate, 1-3 parts of glycerin acrylate/acrylic acid copolymer, 0.9-1.9 parts of dipropylene glycol and 1-3 parts of glycerin;
and (3) component E: 0.1-0.2 part of triethanolamine, 0.1-0.2 part of bisabolol, 0.1-0.5 part of thickening agent B, 0.001-1 part of cactus extract, 0.001-1 part of beta-glucan, 10.1-0.5 part of bioglycan gum, 0.1-0.3 part of lactobacillus/soybean milk fermentation product filtrate, 0.001-1 part of sodium hyaluronate and 0.1-0.5 part of dipropylene glycol.
Further, the emollient comprises triglyceride, petrolatum, propylheptanoate octanoate;
wherein the mass ratio of the triglyceride, the petrolatum and the caprylic propyl heptyl ester is (1-3): (0.1-0.5): (1-3).
Further, the humectant includes butylene glycol, propylene glycol, dipropylene glycol, glycerin, panthenol;
wherein the mass ratio of the butanediol, the propylene glycol, the dipropylene glycol, the glycerol and the panthenol is (1-2): (1-2): (2.4-3.4): (1-2): (0.1-0.2).
Further, the thickener A comprises acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, and acryloyl dimethyl ammonium taurate/VP copolymer;
wherein the mass ratio of acrylic acid (ester)/C10-30 alkanol acrylate crosslinked polymer to the ammonium acryloyldimethyl taurate/VP copolymer is (0.08-0.18): (0.1-0.2).
Further, the thickener B is a mixture of sodium acrylate/sodium acryloyldimethyl taurate copolymer, isohexadecane and polysorbate-80.
Thickener B as described above was obtained from Guangzhou Mega-Heng trade development Co., Ltd
Further, the colorant includes CI 75470.
In a second aspect of the present invention, there is provided:
an activating emulsion comprising the skin activating composition.
Further, the activated emulsion comprises an emulsion, a water agent and a paste agent.
In a third aspect of the present invention, there is provided:
the preparation method of the cosmetic comprises the following steps:
(1) weighing the skin-activating composition components according to claims 1-7;
(2) mixing the component A and heating;
(3) dissolving component B in water;
(4) mixing the component C and heating;
(5) mixing the component D and stirring;
(6) heating the component B, adding the mixed components A, C and D, emulsifying, cooling, adding the component E, and stirring to obtain the activated emulsion.
Wherein the heating temperature of the component A is 70-100 ℃.
The heating temperature of the component C is 70-100 ℃.
The heating temperature of the component B is 70-100 ℃.
The invention has the beneficial effects that:
compared with the prior art, the skin care product has the advantages that various active ingredients such as allantoin, bisabolol, cactus extract, beta-glucan, bioglycan-1, lactobacillus/soybean milk fermentation product filtrate and the like are added, and components with moisturizing, thickening and emulsifying functions in specific combinations are matched to be mutually activated in a synergistic manner, so that the skin care product can simultaneously exert excellent skin activation effects; moreover, a number of practical tests showed that at least 70% of the subjects considered good improvement in skin wrinkles, moisturization, roughness, and uniformity after application of the lotion of the present invention.
Detailed Description
In order to make the objects, technical solutions and technical effects of the present invention more clear, the present invention will be described in further detail with reference to specific embodiments. It should be understood that the detailed description and specific examples, while indicating the preferred embodiment of the invention, are intended for purposes of illustration only and are not intended to limit the scope of the invention.
The experimental materials and reagents used are, unless otherwise specified, all consumables and reagents which are conventionally available from commercial sources.
Allantoin in the present invention was purchased from Guangzhou Ruiping chemical Co., Ltd.
Bisabolol in the present invention was purchased from Shanghai hong Jiu corporation, development Limit.
The cactus extract in the present invention was purchased from Yihui International trade (Shanghai) Co., Ltd.
The beta-glucan in the present invention was purchased from Guangzhou jin Yuan chemical trade company, Inc.
The biosaccharide gum-1 of the present invention is available from Asahi Biotech Limited, Guangzhou.
The lactobacillus/soymilk fermentation product filtrate in the present invention was purchased from Kyowa Korsay, Guangzhou.
Thickener B in the present invention was purchased from guangzhou megabalance trade development ltd.
Example 1 an activating emulsion
The specific components of the activated emulsion in this example include:
and (2) component A: 0.5 part of PEG-60 glyceryl isostearate, 3 parts of triglyceride, 0.5 part of petrolatum and 3 parts of caprylic propyl heptyl ester;
and (B) component: 0.5 part of phytosterol/octyldodecanol lauroyl glutamate, 5 parts of polydimethylsiloxane/vinyl polydimethylsiloxane cross-linked polymer, 0.5 part of isostearic acid, 0.08 part of essence and 0.5 part of olive squalane;
and (3) component C: 2 parts of butanediol, 2 parts of propylene glycol, 3.4 parts of dipropylene glycol, 2 parts of glycerol, 0.2 part of panthenol, 0.4 part of phenoxyethanol, 0.2 part of caprylyl glycol, 0.1 part of allantoin, 0.1 part of tranexamic acid and 754700.2 parts of CI;
and (3) component D: 0.18 part of acrylic acid (ester)/C10-30 alkanol acrylate crosslinked polymer, 0.2 part of ammonium acryloyl dimethyl taurate/VP copolymer, 0.1 part of sodium polyacrylate, 3 parts of glycerol acrylate/acrylic acid copolymer, 1.9 parts of dipropylene glycol and 3 parts of glycerol;
and (3) component E: 0.2 part of triethanolamine, 0.1 part of bisabolol, 0.5 part of thickening agent B, 0.001 part of cactus extract, 0.001 part of beta-glucan, 10.1 parts of bioglycan, 0.3 part of lactobacillus/soybean milk fermentation product filtrate, 0.001 part of sodium hyaluronate and 0.1 part of dipropylene glycol.
Thickener B is a sodium acrylate/sodium acryloyldimethyl taurate copolymer, isohexadecane and polysorbate-80 mixture from guangzhou million-balance trade development ltd.
The preparation method of the cosmetic in the embodiment includes the following steps:
(1) the skin-activating composition components were weighed according to this example;
(2) mixing the raw materials of the component A, and heating to 100 ℃;
(3) dissolving component B in water to disperse component B in water;
(4) mixing the raw materials of the component C, and heating to 100 ℃;
(5) mixing the raw materials of the component D, and stirring and dissolving uniformly;
(6) heating the component B to 100 ℃, then adding the mixed components A, C and D, vacuumizing, emulsifying, cooling to 50 ℃, adding the component E, uniformly stirring, and cooling to 35 ℃ to obtain the activated emulsion.
Example 2 an activating emulsion
The specific components of the activated emulsion in this example include:
and (2) component A: 0.1 part of PEG-60 glyceryl isostearate, 1 part of triglyceride, 0.1 part of petrolatum and 1 part of caprylic propyl heptyl ester;
and (B) component: 0.1 part of phytosterol/octyldodecanol lauroyl glutamate, 3 parts of polydimethylsiloxane/vinyl polydimethylsiloxane cross-linked polymer, 0.1 part of isostearic acid, 0.01 part of essence and 0.1 part of olive squalane;
and (3) component C: 1 part of butanediol, 1 part of propylene glycol, 2.4 parts of dipropylene glycol, 1 part of glycerol, 0.1 part of panthenol, 0.1 part of phenoxyethanol, 0.1 part of caprylyl glycol, 0.2 part of allantoin, 0.2 part of tranexamic acid and 754700.1 parts of CI;
and (3) component D: 0.08 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.1 part of acryloyl dimethyl taurate/VP copolymer, 0.2 part of sodium polyacrylate, 1 part of glycerol acrylate/acrylic acid copolymer, 0.9 part of dipropylene glycol and 1 part of glycerol;
and (3) component E: 0.1 part of triethanolamine, 0.2 part of bisabolol, 0.1 part of thickening agent B, 1 part of cactus extract, 1 part of beta-glucan, 10.5 parts of biological carbohydrate gum, 0.1 part of lactobacillus/soybean milk fermentation product filtrate, 1 part of sodium hyaluronate and 0.5 part of dipropylene glycol.
Thickener B is a sodium acrylate/sodium acryloyldimethyl taurate copolymer, isohexadecane and polysorbate-80 mixture from guangzhou million-balance trade development ltd.
The preparation method of the cosmetic in the embodiment includes the following steps:
(1) the skin-activating composition components were weighed according to this example;
(2) mixing the raw materials of the component A, and heating to 70 ℃;
(3) dissolving component B in water to disperse component B in water;
(4) mixing the raw materials of the component C, and heating to 70 ℃;
(5) mixing the raw materials of the component D, and stirring and dissolving uniformly;
(6) heating the component B to 70 ℃, then adding the mixed components A, C and D, vacuumizing, emulsifying, cooling to 40 ℃, adding the component E, uniformly stirring, and cooling to 30 ℃ to obtain the activated emulsion.
Comparative example 1
The specific components of the cosmetic in this example include:
and (2) component A: 0.5 part of PEG-60 glyceryl isostearate, 3 parts of triglyceride, 0.5 part of petrolatum and 3 parts of caprylic propyl heptyl ester;
and (B) component: 0.5 part of phytosterol/octyldodecanol lauroyl glutamate, 5 parts of polydimethylsiloxane/vinyl polydimethylsiloxane cross-linked polymer, 0.5 part of isostearic acid, 0.08 part of essence and 0.5 part of olive squalane;
and (3) component C: 2 parts of butanediol, 2 parts of propylene glycol, 3.4 parts of dipropylene glycol, 2 parts of glycerol, 0.2 part of panthenol, 0.4 part of phenoxyethanol, 0.2 part of caprylyl glycol, 0.1 part of tranexamic acid and 754700.2 parts of CI;
and (3) component D: 0.18 part of acrylic acid (ester)/C10-30 alkanol acrylate crosslinked polymer, 0.2 part of ammonium acryloyl dimethyl taurate/VP copolymer, 0.1 part of sodium polyacrylate, 3 parts of glycerol acrylate/acrylic acid copolymer, 1.9 parts of dipropylene glycol and 3 parts of glycerol;
and (3) component E: 0.2 part of triethanolamine, 0.1 part of bisabolol, 0.5 part of thickening agent B, 0.001 part of cactus extract, 0.001 part of beta-glucan, 10.1 parts of bioglycan, 0.3 part of lactobacillus/soybean milk fermentation product filtrate, 0.001 part of sodium hyaluronate and 0.1 part of dipropylene glycol.
Thickener B is a sodium acrylate/sodium acryloyldimethyl taurate copolymer, isohexadecane and polysorbate-80 mixture from guangzhou million-balance trade development ltd.
The preparation method of the cosmetic of this example is as shown in example 1.
Comparative example 2
The specific components of the cosmetic in this example include:
and (2) component A: 0.5 part of PEG-60 glyceryl isostearate, 3 parts of triglyceride, 0.5 part of petrolatum and 3 parts of caprylic propyl heptyl ester;
and (B) component: 0.5 part of phytosterol/octyldodecanol lauroyl glutamate, 5 parts of polydimethylsiloxane/vinyl polydimethylsiloxane cross-linked polymer, 0.5 part of isostearic acid, 0.08 part of essence and 0.5 part of olive squalane;
and (3) component C: 2 parts of butanediol, 2 parts of propylene glycol, 3.4 parts of dipropylene glycol, 2 parts of glycerol, 0.2 part of panthenol, 0.4 part of phenoxyethanol, 0.2 part of caprylyl glycol, 0.1 part of allantoin, 0.1 part of tranexamic acid and 754700.2 parts of CI;
and (3) component D: 0.18 part of acrylic acid (ester)/C10-30 alkanol acrylate crosslinked polymer, 0.2 part of ammonium acryloyl dimethyl taurate/VP copolymer, 0.1 part of sodium polyacrylate, 3 parts of glycerol acrylate/acrylic acid copolymer, 1.9 parts of dipropylene glycol and 3 parts of glycerol;
and (3) component E: 0.2 part of triethanolamine, 0.5 part of thickening agent B, 0.001 part of cactus extract, 0.001 part of beta-glucan, 10.1 parts of bioglycan gum, 0.3 part of lactobacillus/soybean milk fermentation product filtrate, 0.001 part of sodium hyaluronate and 0.1 part of dipropylene glycol.
Thickener B is a sodium acrylate/sodium acryloyldimethyl taurate copolymer, isohexadecane and polysorbate-80 mixture from guangzhou million-balance trade development ltd.
The preparation method of the cosmetic of this example is as shown in example 1.
Comparative example 3
The specific components of the cosmetic in this example include:
and (2) component A: 0.5 part of PEG-60 glyceryl isostearate, 3 parts of triglyceride, 0.5 part of petrolatum and 3 parts of caprylic propyl heptyl ester;
and (B) component: 0.5 part of phytosterol/octyldodecanol lauroyl glutamate, 5 parts of polydimethylsiloxane/vinyl polydimethylsiloxane cross-linked polymer, 0.5 part of isostearic acid, 0.08 part of essence and 0.5 part of olive squalane;
and (3) component C: 2 parts of butanediol, 2 parts of propylene glycol, 3.4 parts of dipropylene glycol, 2 parts of glycerol, 0.2 part of panthenol, 0.4 part of phenoxyethanol, 0.2 part of caprylyl glycol, 0.1 part of allantoin, 0.1 part of tranexamic acid and 754700.2 parts of CI;
and (3) component D: 0.18 part of acrylic acid (ester)/C10-30 alkanol acrylate crosslinked polymer, 0.2 part of ammonium acryloyl dimethyl taurate/VP copolymer, 0.1 part of sodium polyacrylate, 3 parts of glycerol acrylate/acrylic acid copolymer, 1.9 parts of dipropylene glycol and 3 parts of glycerol;
and (3) component E: 0.2 part of triethanolamine, 0.1 part of bisabolol, 0.5 part of thickening agent B, 0.001 part of beta-glucan, 10.1 parts of bioglycan gum, 0.3 part of lactobacillus/soybean milk fermentation product filtrate, 0.001 part of sodium hyaluronate and 0.1 part of dipropylene glycol.
Thickener B is a sodium acrylate/sodium acryloyldimethyl taurate copolymer, isohexadecane and polysorbate-80 mixture from guangzhou million-balance trade development ltd.
The preparation method of the cosmetic of this example is as shown in example 1.
Comparative example 4
The specific components of the cosmetic in this example include:
and (2) component A: 0.5 part of PEG-60 glyceryl isostearate, 3 parts of triglyceride, 0.5 part of petrolatum and 3 parts of caprylic propyl heptyl ester;
and (B) component: 0.5 part of phytosterol/octyldodecanol lauroyl glutamate, 5 parts of polydimethylsiloxane/vinyl polydimethylsiloxane cross-linked polymer, 0.5 part of isostearic acid, 0.08 part of essence and 0.5 part of olive squalane;
and (3) component C: 2 parts of butanediol, 2 parts of propylene glycol, 3.4 parts of dipropylene glycol, 2 parts of glycerol, 0.2 part of panthenol, 0.4 part of phenoxyethanol, 0.2 part of caprylyl glycol, 0.1 part of allantoin, 0.1 part of tranexamic acid and 754700.2 parts of CI;
and (3) component D: 0.18 part of acrylic acid (ester)/C10-30 alkanol acrylate crosslinked polymer, 0.2 part of ammonium acryloyl dimethyl taurate/VP copolymer, 0.1 part of sodium polyacrylate, 3 parts of glycerol acrylate/acrylic acid copolymer, 1.9 parts of dipropylene glycol and 3 parts of glycerol;
and (3) component E: 0.2 part of triethanolamine, 0.1 part of bisabolol, 0.5 part of thickening agent B, 0.001 part of cactus extract, 0.001 part of beta-glucan, 10.1 parts of bioglycan, 0.001 part of sodium hyaluronate and 0.1 part of dipropylene glycol.
Thickener B is a sodium acrylate/sodium acryloyldimethyl taurate copolymer, isohexadecane and polysorbate-80 mixture from guangzhou million-balance trade development ltd.
The preparation method of the cosmetic of this example is as shown in example 1.
Comparative example 5
The specific components of the cosmetic in this example include:
and (2) component A: 0.5 part of PEG-60 glyceryl isostearate, 3 parts of triglyceride, 0.5 part of petrolatum and 3 parts of caprylic propyl heptyl ester;
and (B) component: 0.5 part of phytosterol/octyldodecanol lauroyl glutamate, 5 parts of polydimethylsiloxane/vinyl polydimethylsiloxane cross-linked polymer, 0.5 part of isostearic acid, 0.08 part of essence and 0.5 part of olive squalane;
and (3) component C: 2 parts of butanediol, 2 parts of propylene glycol, 3.4 parts of dipropylene glycol, 2 parts of glycerol, 0.2 part of panthenol, 0.4 part of phenoxyethanol, 0.2 part of caprylyl glycol, 0.1 part of allantoin, 0.1 part of tranexamic acid and 754700.2 parts of CI;
and (3) component D: 0.18 part of acrylic acid (ester)/C10-30 alkanol acrylate crosslinked polymer, 0.2 part of ammonium acryloyl dimethyl taurate/VP copolymer, 0.1 part of sodium polyacrylate, 3 parts of glycerol acrylate/acrylic acid copolymer, 1.9 parts of dipropylene glycol and 3 parts of glycerol;
and (3) component E: 0.2 part of triethanolamine, 0.1 part of bisabolol, 0.5 part of thickening agent B, 0.001 part of cactus extract, 10.1 parts of bioglycasin, 0.3 part of lactobacillus/soybean milk fermentation product filtrate, 0.001 part of sodium hyaluronate and 0.1 part of dipropylene glycol.
Thickener B is a sodium acrylate/sodium acryloyldimethyl taurate copolymer, isohexadecane and polysorbate-80 mixture from guangzhou million-balance trade development ltd.
The preparation method of the cosmetic of this example is as shown in example 1.
Comparative example 6
The specific components of the cosmetic in this example include:
and (2) component A: 0.5 part of PEG-60 glyceryl isostearate, 3 parts of triglyceride, 0.5 part of petrolatum and 3 parts of caprylic propyl heptyl ester;
and (B) component: 0.5 part of phytosterol/octyldodecanol lauroyl glutamate, 5 parts of polydimethylsiloxane/vinyl polydimethylsiloxane cross-linked polymer, 0.5 part of isostearic acid, 0.08 part of essence and 0.5 part of olive squalane;
and (3) component C: 2 parts of butanediol, 2 parts of propylene glycol, 3.4 parts of dipropylene glycol, 2 parts of glycerol, 0.2 part of panthenol, 0.4 part of phenoxyethanol, 0.2 part of caprylyl glycol, 0.1 part of allantoin, 0.1 part of tranexamic acid and 754700.2 parts of CI;
and (3) component D: 0.18 part of acrylic acid (ester)/C10-30 alkanol acrylate crosslinked polymer, 0.2 part of ammonium acryloyl dimethyl taurate/VP copolymer, 0.1 part of sodium polyacrylate, 3 parts of glycerol acrylate/acrylic acid copolymer, 1.9 parts of dipropylene glycol and 3 parts of glycerol;
and (3) component E: 0.2 part of triethanolamine, 0.1 part of bisabolol, 0.5 part of thickening agent B, 0.001 part of cactus extract, 0.001 part of beta-glucan, 0.3 part of lactobacillus/soybean milk fermentation product filtrate, 0.001 part of sodium hyaluronate and 0.1 part of dipropylene glycol.
Thickener B is a sodium acrylate/sodium acryloyldimethyl taurate copolymer, isohexadecane and polysorbate-80 mixture from guangzhou million-balance trade development ltd.
The preparation method of the cosmetic of this example is as shown in example 1.
Further effect tests were made on the above examples and comparative examples.
1000 subjects were randomly selected, and the cosmetics of examples 1 to 2 and comparative examples 1 to 6 were used and tested for 24 hours, respectively, and the evaluation of each cosmetic by the subjects was collected, and the cosmetic which was considered to be the best was selected (%, the ratio of the number of subjects who selected the moisturizing emulsion to the total number of subjects).
The results are shown in the following table.
Table 1 somatosensory evaluation of moisturizing emulsions of example 1 and comparative examples 1-8 by subjects
As a result, it was found that 73% of the subjects considered that wrinkles were improved compared to the moisturizing emulsions of comparative examples 1 to 6 after using the moisturizing emulsions of example 1 or 2 after comparing the moisturizing emulsions of comparative examples 1 to 2 and comparative examples 1 to 8; 73% of the subjects considered that the moisturizing emulsions of examples 1 and 2 felt improved skin moisturization compared to the moisturizing emulsions of comparative examples 1-6; 75% of the subjects considered that improvement in skin roughness was felt after using the moisturizing emulsion of example 1 or 2, compared to the moisturizing emulsions of comparative examples 1-6; it was considered that 73% of the subjects felt that improvement in skin uniformity was observed using the moisturizing emulsions of examples 1 or 2, compared to the moisturizing emulsions of comparative examples 1-6. The allantoin, the bisabolol, the cactus extract, the beta-glucan, the bioglycan-1 and the lactobacillus/soybean milk fermentation product filter play an irreplaceable promoting role in the invention.
The above embodiments are preferred embodiments of the present invention, but the present invention is not limited to the above embodiments, and any other changes, modifications, substitutions, combinations, and simplifications which do not depart from the spirit and principle of the present invention should be construed as equivalents thereof, and all such changes, modifications, substitutions, combinations, and simplifications are intended to be included in the scope of the present invention.
Claims (10)
1. A skin activating composition, wherein said skin activating composition comprises the following components:
and (2) component A: PEG-60 glyceryl isostearate and emollient;
and (B) component: phytosterol/octyldodecanol lauroyl glutamate, dimethicone/vinyl dimethicone crosspolymer, isostearic acid, essence, olive squalane;
and (3) component C: humectant, phenoxyethanol, caprylyl glycol, allantoin, tranexamic acid, colorant;
and (3) component D: thickener A, sodium polyacrylate, glycerin acrylate/acrylic acid copolymer, dipropylene glycol and glycerin;
and (3) component E: triethanolamine, bisabolol, a thickening agent B, cactus extract, beta-glucan, bioglycan-1, lactobacillus/soybean milk fermentation product filtrate, sodium hyaluronate and dipropylene glycol.
2. The skin activation composition according to claim 1, wherein the skin activation composition comprises the following components in parts by mass:
and (2) component A: 0.1-0.5 part of PEG-60 glyceryl isostearate and 2.1-6.5 parts of a softening agent;
and (B) component: 0.1-0.5 part of phytosterol/octyldodecanol lauroyl glutamate, 3-5 parts of polydimethylsiloxane/vinyl polydimethylsiloxane cross-linked polymer, 0.1-0.5 part of isostearic acid, 0.01-0.08 part of essence and 0.1-0.5 part of olive squalane;
and (3) component C: 5.5 to 9.6 parts of humectant, 0.1 to 0.4 part of phenoxyethanol, 0.1 to 0.2 part of caprylyl glycol, 0.1 to 0.2 part of allantoin, 0.1 to 0.2 part of tranexamic acid and 0.1 to 0.2 part of colorant;
and (3) component D: 0.18-0.38 part of thickener A, 0.1-0.2 part of sodium polyacrylate, 1-3 parts of glycerin acrylate/acrylic acid copolymer, 0.9-1.9 parts of dipropylene glycol and 1-3 parts of glycerin;
and (3) component E: 0.1-0.2 part of triethanolamine, 0.1-0.2 part of bisabolol, 0.1-0.5 part of thickening agent B, 0.001-1 part of cactus extract, 0.001-1 part of beta-glucan, 10.1-0.5 part of bioglycan gum, 0.1-0.3 part of lactobacillus/soybean milk fermentation product filtrate, 0.001-1 part of sodium hyaluronate and 0.1-0.5 part of dipropylene glycol.
3. The skin activating composition according to any one of claims 1 to 2 wherein the emollient includes triglycerides, petrolatum, propylheptanoate octanoate;
wherein the mass ratio of the triglyceride, the petrolatum and the caprylic propyl heptyl ester is (1-3): (0.1-0.5): (1-3).
4. The skin activation composition of any one of claims 1 to 2, wherein the moisturizer comprises butylene glycol, propylene glycol, dipropylene glycol, glycerin, panthenol;
wherein the mass ratio of the butanediol, the propylene glycol, the dipropylene glycol, the glycerol and the panthenol is (1-2): (1-2): (2.4-3.4): (1-2): (0.1-0.2).
5. The skin-activating composition according to any one of claims 1 to 2, characterized in that the thickener a comprises acrylic acid (ester)/C10-30 alkanol acrylate crosspolymer, ammonium acryloyldimethyltaurate/VP copolymer;
wherein the mass ratio of acrylic acid (ester)/C10-30 alkanol acrylate crosslinked polymer to the ammonium acryloyldimethyl taurate/VP copolymer is (0.08-0.18): (0.1-0.2).
6. The skin-activating composition according to any one of claims 1 to 2 characterised in that the thickener B is a sodium acrylate/sodium acryloyldimethyl taurate copolymer, isohexadecane and polysorbate-80 mixture.
7. The skin activating composition according to any one of claims 1 to 2 wherein the colorant comprises CI 75470.
8. An activated emulsion comprising the skin-activating composition of any one of claims 1 to 7.
9. The activated emulsion of claim 8, wherein the activated emulsion comprises an emulsion, a water aqua, and a cream.
10. A process for the preparation of an activated emulsion according to any one of claims 8 to 9, characterized in that it comprises the following steps:
(1) weighing the skin-activating composition components according to claims 1-7;
(2) mixing the component A and heating;
(3) dissolving component B in water;
(4) mixing the component C and heating;
(5) mixing the component D and stirring;
(6) heating the component B, adding the mixed components A, C and D, emulsifying, cooling, adding the component E, and stirring to obtain the activated emulsion.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010586694.7A CN111714393A (en) | 2020-06-24 | 2020-06-24 | Skin activating composition and activating emulsion thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202010586694.7A CN111714393A (en) | 2020-06-24 | 2020-06-24 | Skin activating composition and activating emulsion thereof |
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| CN111714393A true CN111714393A (en) | 2020-09-29 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112807421A (en) * | 2021-01-08 | 2021-05-18 | 南京贝芙生物科技有限公司 | Composition for improving scar hyperplasia and pigmentation in skin repair process |
-
2020
- 2020-06-24 CN CN202010586694.7A patent/CN111714393A/en active Pending
Non-Patent Citations (1)
| Title |
|---|
| 安婕妤化妆品科技股份有限公司: "安婕妤多效养护平抚水乳", 《HTTP://FTBA.NMPA.GOV.CN:8181/FTBAN/ITOWNET/HZP_BA/FW/PZ.JSP?PROCESSID=20190430140515841C3&NID=20190430140515841C3》, 20 May 2019 (2019-05-20) * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112807421A (en) * | 2021-01-08 | 2021-05-18 | 南京贝芙生物科技有限公司 | Composition for improving scar hyperplasia and pigmentation in skin repair process |
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