CN111686067A - Anti-dandruff moisturizing shampoo and preparation method thereof - Google Patents
Anti-dandruff moisturizing shampoo and preparation method thereof Download PDFInfo
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- CN111686067A CN111686067A CN202010724062.2A CN202010724062A CN111686067A CN 111686067 A CN111686067 A CN 111686067A CN 202010724062 A CN202010724062 A CN 202010724062A CN 111686067 A CN111686067 A CN 111686067A
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
- A61K8/553—Phospholipids, e.g. lecithin
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
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- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/006—Antidandruff preparations
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/02—Preparations for cleaning the hair
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/12—Preparations containing hair conditioners
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
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- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/84—Products or compounds obtained by lyophilisation, freeze-drying
Abstract
The invention discloses an anti-dandruff moisturizing shampoo and a preparation method thereof, wherein the anti-dandruff moisturizing shampoo is prepared from the following raw materials in parts by weight: 7-10.5 parts of biomass nourishing factors, 4-6 parts of smoothing factors, 9-13.5 parts of bio-based surfactants, 2-3 parts of biomass nutrients and 67-78 parts of solvents. The anti-dandruff moisturizing shampoo disclosed by the invention takes various natural biological environment-friendly ingredients as main raw materials, is mild and skin-friendly, is clean and efficient, has a long-acting and obvious effect of moisturizing scalp, can prevent dandruff while removing dandruff, and obviously improves the problems of dry hair.
Description
Technical Field
The invention belongs to the technical field of shampoo, and particularly relates to anti-dandruff moisturizing shampoo and a preparation method thereof.
Background
The shampoo is one of common household bathing products, and has the main functions of washing scalp and hair and keeping the scalp and the hair clean and sanitary. With the improvement of living standard, the requirements of people on the quality and the function of the shampoo are higher and higher, and the shampoo cannot meet the cleaning effect of the shampoo alone. The shampoo products sold on the market at present have various varieties and are suitable for different hair qualities, wherein most of the anti-dandruff shampoo is mainly prepared from a chemically synthesized surfactant and has certain stimulation harm to scalp; most varieties can only remove dandruff, but cannot prevent dandruff, and treat the symptoms and the root causes.
Based on the above, the anti-dandruff shampoo is developed mainly from safe and environment-friendly components such as biomass nourishing factors, bio-based surfactants, softening factors and the like, can clean and remove dandruff, can moisten scalp and prevent dandruff, has better application adaptability and has wide market prospect.
Disclosure of Invention
This section is for the purpose of summarizing some aspects of embodiments of the invention and to briefly introduce some preferred embodiments. In this section, as well as in the abstract and the title of the invention of this application, simplifications or omissions may be made to avoid obscuring the purpose of the section, the abstract and the title, and such simplifications or omissions are not intended to limit the scope of the invention.
The present invention has been made keeping in mind the above and/or other problems occurring in the prior art.
Therefore, the invention aims to overcome the defects in the prior art and provide the anti-dandruff moisturizing shampoo.
In order to solve the technical problems, the invention provides the following technical scheme: the anti-dandruff moisturizing shampoo comprises the following raw materials in parts by weight: 7-10.5 parts of biomass nourishing factors, 4-6 parts of smoothing factors, 9-13.5 parts of bio-based surfactants, 2-3 parts of biomass nutrients and 67-78 parts of solvents.
As a preferable scheme of the anti-dandruff moisturizing shampoo, the anti-dandruff moisturizing shampoo comprises the following components in percentage by weight: the preparation method of the biomass nourishing factor comprises the following steps: drying the animal and plant containing the trophic factors in an oven at 27-32 ℃ for 3-5 hours in advance, adding the dried animal and plant containing the trophic factors into a medicine grinder, fully grinding, soaking in 75-95% ethanol water solution, adding a small amount of sodium carbonate, uniformly mixing the whole system, soaking for 24 hours at-15 ℃, and filtering to obtain a primary extracting solution, wherein the mass ratio of the animal and plant containing the trophic factors to the ethanol water solution to the sodium carbonate is 1: 15-30: 0.1-0.2; and (2) dialyzing and separating the primary extract obtained by filtering at room temperature by using a dialysis membrane with the molecular weight cutoff of 8000-18000 for 1-3 days, performing rotary evaporation concentration treatment after dialysis, performing suction filtration on the whole system at-15 ℃ through filter paper with the aperture of 1-5 mu m, wherein the pump pressure is 0.01-0.03 MPa, performing freeze drying on the obtained filtrate, performing ultrasonic dispersion on the filtrate in butanediol, and performing freeze drying to obtain solid particles, wherein the mass ratio of the solid particles to the butanediol is 1: 3-5, so that the biomass nourishing factor is obtained.
As a preferable scheme of the anti-dandruff moisturizing shampoo, the anti-dandruff moisturizing shampoo comprises the following components in percentage by weight: the animal and plant containing nourishing factors is a composition of two or more of aloe, cactus, sisal, ramie, fresh ginger and shallot and two or more of krill, Procambarus clarkii, pig bone and ox bone.
As a preferable scheme of the anti-dandruff moisturizing shampoo, the anti-dandruff moisturizing shampoo comprises the following components in percentage by weight: the softening factor is a composition of isopropyl myristate, fatty glyceride polyoxyethylene ether and polyamine amide.
As a preferable scheme of the anti-dandruff moisturizing shampoo, the anti-dandruff moisturizing shampoo comprises the following components in percentage by weight: the bio-based surfactant is a composition of soapberry saponin, tea saponin, a protein surfactant, yolk essence and cephalin.
As a preferable scheme of the anti-dandruff moisturizing shampoo, the anti-dandruff moisturizing shampoo comprises the following components in percentage by weight: the biomass nutrient is a composition of vitamin E, vitamin C, nicotinamide and hyaluronic acid.
As a preferable scheme of the anti-dandruff moisturizing shampoo, the anti-dandruff moisturizing shampoo comprises the following components in percentage by weight: the solvent is a composition of deionized water and glycerol.
The invention further aims to overcome the defects in the prior art and provide a preparation method of the anti-dandruff moisturizing shampoo.
In order to solve the technical problems, the invention provides the following technical scheme: a preparation method of anti-dandruff moisturizing shampoo comprises the following specific steps: stirring and dissolving 3-4 parts of glycerol, 1-2 parts of isopropyl myristate, 1.5-2 parts of fatty glyceride polyoxyethylene ether, 1.5-2 parts of polyamine amide and 32-37 parts of deionized water until the mixture is uniform and clear, then adding 7-10.5 parts of biomass nourishing factor, 3-4.5 parts of soapnut saponin, 2-3 parts of tea saponin, 2-3 parts of protein surfactant, 1-1.5 parts of yolk and 1-1.5 parts of cephalin slowly, simultaneously stirring for 18-22 min at 340-380 rpm by using a high-speed stirrer, then adding 32-37 parts of deionized water, 0.5-0.75 part of vitamin E, 0.25-0.5 part of vitamin C, 0.25-0.5 part of nicotinamide and 1-1.25 parts of hyaluronic acid, and continuously stirring at 420-480 rpm and 26 ℃ for 13-17 min, and adjusting the pH value to 5.3-6.0 by using a small amount of citric acid to obtain uniform and viscous gel, namely the anti-dandruff moisturizing shampoo.
The invention has the beneficial effects that:
(1) the anti-dandruff moisturizing shampoo disclosed by the invention adopts various natural biological environment-friendly components as main raw materials, is mild, skin-friendly, non-irritant, efficient and clean, can prevent dandruff increase, scalp itching, dryness of hair and the like, is exquisite and rich in foam, can prevent dandruff more, has a remarkable effect of moisturizing scalp, and is particularly suitable for people with dry and mixed dry hair. The anti-dandruff moisturizing shampoo disclosed by the invention achieves the functions of efficiently cleaning and removing dandruff mainly through the compounding of the bio-based surfactant and the smoothing factor: one end of the bio-based surfactant molecule is hydrophilic, and the other end is hydrophobic, so that stains such as dust, oil stain, dandruff and the like can be emulsified into small droplets or stripped and surrounded, and the stains can be conveniently removed; the softening factor enhances the penetration, foaming and covering effects of the shampoo on the surface of the scalp, is beneficial to the compatibility of oily components and aqueous components, and simultaneously softens cutin, thereby further improving the cleaning effect on the scalp and the hair. Experiments prove that the reasonable compounding effect of the two components is far better than that of any one of the two components which are independently used, which shows that the two components have the synergistic effect.
(2) The dandruff removing and moisturizing shampoo disclosed by the invention has the moisturizing and moisturizing effects on scalp and hair, and is derived from the effects of biomass nourishing factors, softening factors and biomass nutrients: the biomass nourishing factors in reasonable proportion provide sufficient moisture for scalp and hair root by the film forming, moisture absorption and anti-drying effects of natural active substances contained in the biomass nourishing factors, and firmly lock the water; the supple factor is helpful for the penetration of the biomass nourishing factor to the scalp and the hair, so that the efficacy of the supple factor is fully exerted; the biomass nutrient can promote metabolism of scalp and hair root cells, make the cells full, soften cutin and prevent the drying of old thick cutin. This fully explains the mechanism of the cooperative and synergistic effects of the three ingredients.
(3) According to the anti-dandruff moisturizing shampoo disclosed by the invention, the addition of the biomass nourishing factors, the smoothing factors and the biomass nutrients surprisingly endows the shampoo with an effect of preventing dandruff generation, and the dandruff preventing effect after reasonable compounding of the three components is far better than that of one component, which shows that the biomass nourishing factors, the smoothing factors and the biomass nutrients have a synergistic effect.
(4) The anti-dandruff moisturizing shampoo disclosed by the invention is prepared by adding deionized water twice, and adding biomass nutrients in the follow-up manner, and experiments prove that only by the addition sequence and the distribution proportion, the finally obtained shampoo has the emulsion type of oil-in-water, a moisturizing and moisturizing protective film can be formed on the surfaces of the scalp and the hair, and only the anti-dandruff moisturizing shampoo in the type can be more stable, various functions can be fully exerted, otherwise, the effect is greatly reduced.
(5) In the preparation process of the anti-dandruff moisturizing shampoo, if only one of animal or plant components is used as a raw material, the anti-dandruff moisturizing shampoo can finally generate obvious negative effects on the effects of preventing dandruff and moisturizing scalp and hair, which indicates that the animal and plant components have synergistic interaction.
Detailed Description
In order to make the aforementioned objects, features and advantages of the present invention more comprehensible, specific embodiments thereof are described in detail below with reference to examples of the specification.
In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention, but the present invention may be practiced in other ways than those specifically described and will be readily apparent to those of ordinary skill in the art without departing from the spirit of the present invention, and therefore the present invention is not limited to the specific embodiments disclosed below.
Furthermore, reference herein to "one embodiment" or "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment is included in at least one implementation of the invention. The appearances of the phrase "in one embodiment" in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments.
The cleaning and decontaminating performance of the invention is tested as follows: weighing mass m1The hair is soaked in prepared dirt, and the dirt formula comprises the following raw materials in percentage by mass: 15-16% of palmitic acid, 8-9% of paraffin, 5-6% of tetradecanoic acid, 13-14% of oleic acid, 16-18% of glyceryl stearate, 1-2% of lecithin, 0.5-1% of carbon black and 0.5-1% of dust; taking out, naturally air drying in shade, and weighing mass m2Calculating the oil stain mass m before washing2-m1(ii) a Preparing shampoo into 0.6% washing solution with 2000mg/kg hard water, washing stained hair with the washing solution, rinsing in cold water for 1 time, taking out, naturally air drying in shade, and weighing mass m3And calculating the mass m of the washed oil stain2-m3；
Cleaning and stain removal performance (%) (m)2-m3)/(m2-m1)×100。
The invention tests the moisturizing performance: according to the Young modulus values before and after washing hair, the average value of more than 10 people (dry or dry skin people) is obtained by an evaluation group, the using amount is 2 g/person, and the water temperature is 39 ℃. The low water holding capacity of hair tends to reduce the strength of hair, dry, brittle, dull and difficult to shape, and in this case, the surface coat of hair is damaged to make it porous and difficult to retain water. The Young's modulus is evaluated by measuring the tensile strength of hair to indirectly reflect the integrity of the keratin network of the hair, the health of the hair and the moisturizing performance of the hair. The smaller the Young's modulus value, the better the hair moisturizing performance. The Young modulus value in the invention is measured: taking a hair sample to be measured under the conditions of room temperature and relative humidity (30 +/-3)%, fixing one end of a hair on a clamp of a Young modulus instrument, applying fixed low stress to a linear hooke deformation area, and calculating the Young modulus value through a slope. The experiment was repeated 10 times and the mean was calculated.
Example 1
The embodiment provides a preparation method of anti-dandruff moisturizing shampoo, which comprises the following steps:
(1) drying cactus, ramie, fresh ginger, procambarus clarkii and pig bones (the mass ratio is 1.2:1:0.8:1.5:1.2) in an oven at 32 ℃ for 4 hours in advance, fully crushing in a medicine crusher, soaking in 95% ethanol water solution, adding a small amount of soda ash containing a nourishing factor, the mass ratio of the ethanol water solution to the soda ash is 1:22.5:0.15, uniformly mixing the whole system, soaking at-15 ℃ for 24 hours, and filtering to obtain a primary extracting solution;
dialyzing and separating the primary extract obtained by filtering at room temperature by using a dialysis membrane with the molecular weight cutoff of 18000 for 3 days, performing rotary evaporation and concentration treatment after dialysis is finished, performing suction filtration on the whole system at-15 ℃ through filter paper with the pore diameter of 5 mu m, wherein the pump pressure is 0.03MPa, performing freeze drying on the obtained filtrate, and performing ultrasonic dispersion on the obtained filtrate in butanediol (the mass ratio of solid particles obtained after freeze drying to butanediol is 1:4), thereby obtaining the biomass nourishing factor.
(2) 3.5 parts of glycerol, 1.5 parts of isopropyl myristate, 1.75 parts of fatty glyceride polyoxyethylene ether, 1.75 parts of polyamine amide and 34.5 parts of deionized water are stirred and dissolved until the mixture is uniform and clear, then 8.75 parts of biomass nourishing factor, 3.75 parts of soapnut saponin, 2.5 parts of tea saponin, 2.5 parts of protein surfactant, 1.25 parts of egg yolk and 1.25 parts of cephalin are slowly added into the mixture, and simultaneously, a high-speed stirrer is used for stirring for 20min at 360rpm, at the moment, 34.5 parts of deionized water, 0.625 parts of vitamin E, 0.375 parts of vitamin C, 0.375 parts of nicotinamide and 1.125 parts of hyaluronic acid are added, the mixture is continuously stirred for 15min at 450rpm and 26 ℃, a small amount of citric acid is used for adjusting the pH value to be 6.0, and then uniform and viscous gel is obtained, namely the dandruff removing and moistening shampoo.
And (3) testing results: the obtained dandruff removing and moistening shampoo is uniform and stable, and has moderate viscosity.
Comparative example 1
(1) Drying cactus, ramie, fresh ginger, procambarus clarkii and pig bones (the mass ratio is 1.2:1:0.8:1.5:1.2) in an oven at 32 ℃ for 4 hours in advance, fully crushing in a medicine crusher, soaking in 95% ethanol water solution, adding a small amount of soda ash containing a nourishing factor, the mass ratio of the ethanol water solution to the soda ash is 1:22.5:0.15, uniformly mixing the whole system, soaking at-15 ℃ for 24 hours, and filtering to obtain a primary extracting solution;
dialyzing and separating the primary extract obtained by filtering at room temperature by using a dialysis membrane with the molecular weight cutoff of 18000 for 3 days, performing rotary evaporation and concentration treatment after dialysis is finished, performing suction filtration on the whole system at-15 ℃ through filter paper with the pore diameter of 5 mu m, wherein the pump pressure is 0.03MPa, performing freeze drying on the obtained filtrate, and performing ultrasonic dispersion on the obtained filtrate in butanediol (the mass ratio of solid particles obtained after freeze drying to butanediol is 1:4), thereby obtaining the biomass nourishing factor.
(2) 4.75 parts of glycerol, 1.5 parts of isopropyl myristate, 1.75 parts of fatty glyceride polyoxyethylene ether, 1.75 parts of polyamine amide and 39.5 parts of deionized water are stirred and dissolved until the mixture is uniform and clear, then 8.75 parts of biomass nourishing factor is slowly added into the mixture, a high-speed stirrer is used for stirring at 360rpm for 20min, at the same time, 39.5 parts of deionized water, 0.625 parts of vitamin E, 0.375 parts of vitamin C, 0.375 parts of nicotinamide and 1.125 parts of hyaluronic acid are added, stirring is continuously carried out at 450rpm and 26 ℃ for 15min, and a small amount of citric acid is used for adjusting the pH value to 6.0, so that uniform and viscous gel, namely the anti-dandruff shampoo (compared with the embodiment 1, no bio-based surfactant is added, and the balance is supplemented by a solvent) is obtained.
And (3) testing results: the obtained dandruff removing and moistening shampoo is uniform and stable, and has moderate viscosity.
Comparative example 2
(1) Drying cactus, ramie, fresh ginger, procambarus clarkii and pig bones (the mass ratio is 1.2:1:0.8:1.5:1.2) in an oven at 32 ℃ for 4 hours in advance, fully crushing in a medicine crusher, soaking in 95% ethanol water solution, adding a small amount of soda ash containing a nourishing factor, the mass ratio of the ethanol water solution to the soda ash is 1:22.5:0.15, uniformly mixing the whole system, soaking at-15 ℃ for 24 hours, and filtering to obtain a primary extracting solution;
dialyzing and separating the primary extract obtained by filtering at room temperature by using a dialysis membrane with the molecular weight cutoff of 18000 for 3 days, performing rotary evaporation and concentration treatment after dialysis is finished, performing suction filtration on the whole system at-15 ℃ through filter paper with the pore diameter of 5 mu m, wherein the pump pressure is 0.03MPa, performing freeze drying on the obtained filtrate, and performing ultrasonic dispersion on the obtained filtrate in butanediol (the mass ratio of solid particles obtained after freeze drying to butanediol is 1:4), thereby obtaining the biomass nourishing factor.
(2) Stirring and dissolving 4.5 parts of glycerol and 36.5 parts of deionized water until the mixture is uniform and clear, then slowly adding 8.75 parts of biomass nourishing factor, 3.75 parts of soapnut saponin, 2.5 parts of tea saponin, 2.5 parts of protein surfactant, 1.25 parts of yolk essence and 1.25 parts of cephalin into the mixture, stirring the mixture for 20min at 360rpm by using a high-speed stirrer, then adding 36.5 parts of deionized water, 0.625 parts of vitamin E, 0.375 parts of vitamin C, 0.375 parts of nicotinamide and 1.125 parts of hyaluronic acid, continuously stirring the mixture for 15min at 450rpm and 26 ℃, and adjusting the pH value to be 6.0 by using a small amount of citric acid to obtain uniform and viscous gel, namely the dandruff removing and moistening shampoo (the pH value is not added with a softening factor compared with that of the shampoo in the embodiment 1, and the balance is supplemented with a solvent).
And (3) testing results: the obtained dandruff removing and moistening shampoo is uniform and stable, and has moderate viscosity.
Comparative example 3
(1) 3.5 parts of glycerol, 1.5 parts of isopropyl myristate, 1.75 parts of fatty glyceride polyoxyethylene ether, 1.75 parts of polyamine amide and 34.5 parts of deionized water are stirred and dissolved until uniform clarification is achieved, then 3.75 parts of soapnut saponin, 2.5 parts of tea saponin, 2.5 parts of protein surfactant, 1.25 parts of lecithin and 1.25 parts of cephalin are slowly added into the mixture, a high-speed stirrer is used for stirring at 360rpm for 20min, at the moment, 34.5 parts of deionized water, 0.625 part of vitamin E, 0.375 part of vitamin C, 0.375 part of nicotinamide and 1.125 parts of hyaluronic acid are added, the mixture is continuously stirred at 450rpm and 26 ℃ for 15min, and a small amount of citric acid is used for adjusting the pH value to be between 5.3 and 6.0, so that uniform and viscous gel is obtained, namely the dandruff removing and moistening shampoo (no biomass nourishing factor is added compared with the shampoo in example 1).
And (3) testing results: the obtained dandruff removing and moistening shampoo is uniform and stable, and has moderate viscosity.
Comparative example 4
(1) Drying cactus, ramie and fresh ginger (the mass ratio is 1.2:1:0.8) in an oven at 32 ℃ for 4 hours in advance, fully crushing in a medicine crusher, soaking in 95% ethanol water solution, adding a small amount of soda ash, the mass ratio of the animal and plant containing the nourishing factors to the ethanol water solution to the soda ash is 1:22.5:0.15, uniformly mixing the whole system, soaking at-15 ℃ for 24 hours, and filtering to obtain a primary extracting solution;
dialyzing and separating the primary extract obtained by filtering at room temperature by using a dialysis membrane with the molecular weight cutoff of 18000 for 3 days, performing rotary evaporation and concentration treatment after dialysis is finished, performing suction filtration on the whole system at-15 ℃ through filter paper with the pore diameter of 5 mu m, wherein the pump pressure is 0.03MPa, performing freeze drying on the obtained filtrate, and performing ultrasonic dispersion on the obtained filtrate in butanediol (the mass ratio of solid particles obtained after freeze drying to butanediol is 1:4), thereby obtaining the biomass nourishing factor.
(2) 3.5 parts of glycerol, 1.5 parts of isopropyl myristate, 1.75 parts of fatty glyceride polyoxyethylene ether, 1.75 parts of polyamine amide and 34.5 parts of deionized water are stirred and dissolved until uniform clarification is achieved, then 8.75 parts of biomass nourishing factor, 3.75 parts of soapnut saponin, 2.5 parts of tea saponin, 2.5 parts of protein surfactant, 1.25 parts of egg yolk and 1.25 parts of cephalin are slowly added into the mixture, and simultaneously a high-speed stirrer is used for stirring at 360rpm for 20min, at the moment, 34.5 parts of deionized water, 0.625 parts of vitamin E, 0.375 parts of vitamin C, 0.375 parts of nicotinamide and 1.125 parts of hyaluronic acid are added, the mixture is continuously stirred at 450rpm and 26 ℃ for 15min, and a small amount of citric acid is used for adjusting the pH value to be 6.0, so that uniform and viscous gel is obtained, namely the dandruff removing and moistening shampoo (compared with the biomass nourishing factor of example 1, only plant raw materials are used).
And (3) testing results: the obtained dandruff removing and moistening shampoo is uniform and stable, and has moderate viscosity.
Comparative example 5
(1) Drying cactus, ramie, fresh ginger, procambarus clarkii and pig bones (the mass ratio is 1.2:1:0.8:1.5:1.2) in an oven at 32 ℃ for 4 hours in advance, fully crushing in a medicine crusher, soaking in 95% ethanol water solution, adding a small amount of soda ash containing a nourishing factor, the mass ratio of the ethanol water solution to the soda ash is 1:22.5:0.15, uniformly mixing the whole system, soaking at-15 ℃ for 24 hours, and filtering to obtain a primary extracting solution;
dialyzing and separating the primary extract obtained by filtering at room temperature by using a dialysis membrane with the molecular weight cutoff of 18000 for 3 days, performing rotary evaporation and concentration treatment after dialysis is finished, performing suction filtration on the whole system at-15 ℃ through filter paper with the pore diameter of 5 mu m, wherein the pump pressure is 0.03MPa, performing freeze drying on the obtained filtrate, and performing ultrasonic dispersion on the obtained filtrate in butanediol (the mass ratio of solid particles obtained after freeze drying to butanediol is 1:4), thereby obtaining the biomass nourishing factor.
(2) 3.5 parts of glycerol, 1.5 parts of isopropyl myristate, 1.75 parts of fatty glyceride polyoxyethylene ether, 1.75 parts of polyamine amide and 34.5 parts of deionized water are stirred and dissolved until the mixture is uniform and clear, then 8.75 parts of biomass nourishing factor, 3.75 parts of soapnut saponin, 2.5 parts of tea saponin, 2.5 parts of protein surfactant, 1.25 parts of egg yolk and 1.25 parts of cephalin are slowly added into the mixture, a high-speed stirrer is used for stirring for 20min at 360rpm, at the moment, 34.5 parts of deionized water is added, the mixture is continuously stirred for 15min at 450rpm and 26 ℃, and a small amount of citric acid is used for adjusting the pH value to be 6.0, so that uniform and viscous gel, namely the dandruff removing and moistening shampoo (compared with the shampoo in the example 1, no biomass nutrient is added).
And (3) testing results: the obtained dandruff removing and moistening shampoo is uniform and stable, and has moderate viscosity.
Comparative example 6
(1) Drying cactus, ramie, fresh ginger, procambarus clarkii and pig bones (the mass ratio is 1.2:1:0.8:1.5:1.2) in an oven at 32 ℃ for 4 hours in advance, fully crushing in a medicine crusher, soaking in 95% ethanol water solution, adding a small amount of soda ash containing a nourishing factor, the mass ratio of the ethanol water solution to the soda ash is 1:22.5:0.15, uniformly mixing the whole system, soaking at-15 ℃ for 24 hours, and filtering to obtain a primary extracting solution;
dialyzing and separating the primary extract obtained by filtering at room temperature by using a dialysis membrane with the molecular weight cutoff of 18000 for 3 days, performing rotary evaporation and concentration treatment after dialysis is finished, performing suction filtration on the whole system at-15 ℃ through filter paper with the pore diameter of 5 mu m, wherein the pump pressure is 0.03MPa, performing freeze drying on the obtained filtrate, and performing ultrasonic dispersion on the obtained filtrate in butanediol (the mass ratio of solid particles obtained after freeze drying to butanediol is 1:4), thereby obtaining the biomass nourishing factor.
(2) 3.5 parts of glycerol, 1.5 parts of isopropyl myristate, 1.75 parts of fatty glyceride polyoxyethylene ether, 1.75 parts of polyamine amide, 0.625 parts of vitamin E, 0.375 parts of vitamin C, 0.375 parts of nicotinamide, 1.125 parts of hyaluronic acid and 69 parts of deionized water are stirred and dissolved until uniform and clear, then 8.75 parts of biomass nourishing factor, 3.75 parts of sapindus saponin, 2.5 parts of tea saponin, 2.5 parts of protein surfactant, 1.25 parts of egg yolk and 1.25 parts of cephalin are slowly added into the mixture, and simultaneously a high-speed stirrer is used for stirring at 450rpm for 35min, and a small amount of citric acid is used for adjusting the pH value to be 6.0, so that uniform and viscous gel is obtained, namely the dandruff removing and moistening shampoo (compared with the example 1, the deionized water is added once, and the adding sequence of the biomass nutrients is advanced).
And (3) testing results: the obtained dandruff-removing moisturizing shampoo is uniform but not stable enough, and has low viscosity.
The anti-dandruff efficacy of the products prepared in example 1 and comparative examples 1 to 6 is characterized by using malassezia inhibition activity as an index through a malassezia inhibition experiment, and the performance measurement results are shown in table 1.
TABLE 1
In conclusion, the anti-dandruff moisturizing shampoo disclosed by the invention adopts various natural biological environment-friendly components as main raw materials, is mild, skin-friendly, non-irritant, efficient and clean, can prevent dandruff increase, scalp itching, dryness of hair and the like, is exquisite and rich in foam, can prevent dandruff by removing dandruff, has a remarkable effect of moisturizing scalp, and is particularly suitable for people with dry and mixed dry hair.
The anti-dandruff moisturizing shampoo disclosed by the invention achieves the functions of efficiently cleaning and removing dandruff mainly through the compounding of the bio-based surfactant and the smoothing factor: one end of the bio-based surfactant molecule is hydrophilic, and the other end is hydrophobic, so that stains such as dust, oil stain, dandruff and the like can be emulsified into small droplets or stripped and surrounded, and the stains can be conveniently removed; the softening factor enhances the penetration, foaming and covering effects of the shampoo on the surface of the scalp, is beneficial to the compatibility of oily components and aqueous components, and simultaneously softens cutin, thereby further improving the cleaning effect on the scalp and the hair. Experiments prove that the reasonable compounding effect of the two components is far better than that of any one of the two components which are independently used, which shows that the two components have the synergistic effect. The dandruff removing and moisturizing shampoo disclosed by the invention has the moisturizing and moisturizing effects on scalp and hair, and is derived from the effects of biomass nourishing factors, softening factors and biomass nutrients: the biomass nourishing factors in reasonable proportion provide sufficient moisture for scalp and hair root by the film forming, moisture absorption and anti-drying effects of natural active substances contained in the biomass nourishing factors, and firmly lock the water; the supple factor is helpful for the penetration of the biomass nourishing factor to the scalp and the hair, so that the efficacy of the supple factor is fully exerted; the biomass nutrient can promote metabolism of scalp and hair root cells, make the cells full, soften cutin and prevent the drying of old thick cutin. This fully explains the mechanism of the cooperative and synergistic effects of the three ingredients.
According to the anti-dandruff moisturizing shampoo disclosed by the invention, the addition of the biomass nourishing factors, the smoothing factors and the biomass nutrients surprisingly endows the shampoo with an effect of preventing dandruff generation, and the dandruff preventing effect after reasonable compounding of the three components is far better than that of one component, which shows that the biomass nourishing factors, the smoothing factors and the biomass nutrients have a synergistic effect.
The anti-dandruff moisturizing shampoo disclosed by the invention is prepared by adding deionized water twice, and adding biomass nutrients in the follow-up manner, and experiments prove that only by the addition sequence and the distribution proportion, the finally obtained shampoo has the emulsion type of oil-in-water, a moisturizing and moisturizing protective film can be formed on the surfaces of the scalp and the hair, and only the anti-dandruff moisturizing shampoo in the type can be more stable, various functions can be fully exerted, otherwise, the effect is greatly reduced.
In the preparation process of the anti-dandruff moisturizing shampoo, if only one of animal or plant components is used as a raw material, the anti-dandruff moisturizing shampoo can finally generate obvious negative effects on the effects of preventing dandruff and moisturizing scalp and hair, which indicates that the animal and plant components have synergistic interaction.
It should be noted that the above-mentioned embodiments are only for illustrating the technical solutions of the present invention and not for limiting, and although the present invention has been described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that modifications or equivalent substitutions may be made on the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention, which should be covered by the claims of the present invention.
Claims (8)
1. An anti-dandruff moisturizing shampoo is characterized in that: the anti-dandruff moisturizing shampoo comprises the following raw materials in parts by weight: 7-10.5 parts of biomass nourishing factors, 4-6 parts of smoothing factors, 9-13.5 parts of bio-based surfactants, 2-3 parts of biomass nutrients and 67-78 parts of solvents.
2. The anti-dandruff moisturizing shampoo according to claim 1, characterized in that: the preparation method of the biomass nourishing factor comprises the following steps:
drying the animal and plant containing the trophic factors in an oven at 27-32 ℃ for 3-5 hours in advance, adding the dried animal and plant containing the trophic factors into a medicine grinder, fully grinding, soaking in 75-95% ethanol water solution, adding a small amount of sodium carbonate, uniformly mixing the whole system, soaking for 24 hours at-15 ℃, and filtering to obtain a primary extracting solution, wherein the mass ratio of the animal and plant containing the trophic factors to the ethanol water solution to the sodium carbonate is 1: 15-30: 0.1-0.2;
and (2) dialyzing and separating the primary extract obtained by filtering at room temperature by using a dialysis membrane with the molecular weight cutoff of 8000-18000 for 1-3 days, performing rotary evaporation concentration treatment after dialysis, performing suction filtration on the whole system at-15 ℃ through filter paper with the aperture of 1-5 mu m, wherein the pump pressure is 0.01-0.03 MPa, performing freeze drying on the obtained filtrate, performing ultrasonic dispersion on the filtrate in butanediol, and performing freeze drying to obtain solid particles, wherein the mass ratio of the solid particles to the butanediol is 1: 3-5, so that the biomass nourishing factor is obtained.
3. The method for preparing biomass nourishing factors according to claim 2, characterized in that: the animal and plant containing nourishing factors is a composition of two or more of aloe, cactus, sisal, ramie, fresh ginger and shallot and two or more of krill, Procambarus clarkii, pig bone and ox bone.
4. The anti-dandruff moisturizing shampoo according to claim 1, characterized in that: the softening factor is a composition of isopropyl myristate, fatty glyceride polyoxyethylene ether and polyamine amide.
5. The anti-dandruff moisturizing shampoo according to claim 1, characterized in that: the bio-based surfactant is a composition of soapberry saponin, tea saponin, a protein surfactant, yolk and cephalin.
6. The anti-dandruff moisturizing shampoo according to claim 1, characterized in that: the biomass nutrient is a composition of vitamin E, vitamin C, nicotinamide and hyaluronic acid.
7. The anti-dandruff moisturizing shampoo according to claim 1, characterized in that: the solvent is a composition of deionized water and glycerol.
8. The preparation method of the anti-dandruff moisturizing shampoo according to any one of claims 1 to 7, which is characterized by comprising the following specific steps:
stirring and dissolving 3-4 parts of glycerol, 1-2 parts of isopropyl myristate, 1.5-2 parts of fatty glyceride polyoxyethylene ether, 1.5-2 parts of polyamine amide and 32-37 parts of deionized water until the mixture is uniform and clear, then adding 7-10.5 parts of biomass nourishing factor, 3-4.5 parts of soapnut saponin, 2-3 parts of tea saponin, 2-3 parts of protein surfactant, 1-1.5 parts of yolk and 1-1.5 parts of cephalin slowly, simultaneously stirring for 18-22 min at 340-380 rpm by using a high-speed stirrer, then adding 32-37 parts of deionized water, 0.5-0.75 part of vitamin E, 0.25-0.5 part of vitamin C, 0.25-0.5 part of nicotinamide and 1-1.25 parts of hyaluronic acid, and continuously stirring at 420-480 rpm and 26 ℃ for 13-17 min, and adjusting the pH value to 5.3-6.0 by using a small amount of citric acid to obtain uniform and viscous gel, namely the anti-dandruff moisturizing shampoo.
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| CN103702656A (en) * | 2011-05-25 | 2014-04-02 | 株式会社资生堂 | Shampoo composition |
| CN105534820A (en) * | 2016-01-25 | 2016-05-04 | 柳州三农科技有限公司 | Pure natural anti-dandruff hair-moisturizing shampoo and preparation method thereof |
| KR20170065260A (en) * | 2015-12-03 | 2017-06-13 | 조길수 | Method for producing of shampoos customized by individual and shampoos by the method |
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| CN103702656A (en) * | 2011-05-25 | 2014-04-02 | 株式会社资生堂 | Shampoo composition |
| CN103349622A (en) * | 2013-07-15 | 2013-10-16 | 澳宝化妆品（惠州）有限公司 | Special mild soft repairing anti-dandruff shampoo |
| KR20170065260A (en) * | 2015-12-03 | 2017-06-13 | 조길수 | Method for producing of shampoos customized by individual and shampoos by the method |
| CN105534820A (en) * | 2016-01-25 | 2016-05-04 | 柳州三农科技有限公司 | Pure natural anti-dandruff hair-moisturizing shampoo and preparation method thereof |
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