CN111671670B

CN111671670B - Moisturizing essence toner

Info

Publication number: CN111671670B
Application number: CN202010782895.4A
Authority: CN
Inventors: 黄美红
Original assignee: Suzhou Misifu Cosmetic Co ltd
Current assignee: Suzhou Misifu Cosmetic Co ltd
Priority date: 2020-08-06
Filing date: 2020-08-06
Publication date: 2023-03-28
Anticipated expiration: 2040-08-06
Also published as: CN111671670A

Abstract

The invention discloses a moisturizing essence toner which is prepared from the following raw materials in percentage by weight: dipotassium glycyrrhizinate 0.02-0.08%; 26.5 to 3.5 percent of glycerol polyether; 0.2 to 0.6 percent of PEG-5 glyceryl stearate; polysorbate-60.1-0.5%; 4.0-8.0% of biological polysaccharide humectant; 0.02-0.08% of EDTA disodium; 0.03-0.07% of nisin; the balance being water. The moisturizing essence toner disclosed by the invention can effectively remove dirt and oily secretion on skin, and keep the stratum corneum of the skin to be soft and moist by moderate moisture.

Description

Moisturizing essence toner

Technical Field

The invention relates to the technical field of cosmetics, and particularly relates to moisturizing essence toner.

Background

Most skin problems are caused by a lack of water in the skin. When the skin is deficient in water, cell metabolism, information transmission and the like are affected and even disorders occur, causing problems such as dry skin, roughness, loss of luster, reduced elasticity, increased or deepened wrinkles, increased pigmentation and the like, and even causing skin barrier dysfunction, which not only increases the susceptibility to skin diseases, but also induces or aggravates skin diseases such as dry dermatitis, atopic dermatitis, psoriasis, ichthyosis, acne and seborrheic dermatitis and the like. The water content of the stratum corneum of healthy skin should be kept at 10% -20%, and when the water content of the stratum corneum is sufficient, the skin assumes a soft, smooth, tender and elastic state, and less than 10% of the skin causes the above-mentioned skin problems.

Moisturizing is achieved by preventing the loss of moisture from the skin and absorbing the moisture from the external environment. For example, mineral oil, stearate, silicone oil, etc. having a certain lubricating effect are used to prevent moisture from evaporating, thereby achieving the purpose of moisture retention (patent document 1,cn104887595a); substances with moisture absorption effects such as glycerin, 1, 2-propylene glycol, lactic acid, urea, allantoin and the like are adopted to absorb water from the external environment and the deep layer of the skin to the stratum corneum so as to achieve the purpose of moisture preservation (patent document 2,CN108434033A); the purpose of moisturizing is achieved by using a substance capable of forming a network structure by binding with water molecules, such as hyaluronic acid, dextran, or ceramide (patent document 3,cn106109265a). However, the above moisturizers are generally only suitable for moisturizing functions in normal environments, and it is difficult to obtain a desired moisturizing effect in dry environments with low humidity. Meanwhile, the moisturizing effect of the moisturizing agent is poor in timeliness, the moisturizing effect can be achieved only in a short time, the long-time moisturizing effect is remarkably reduced, and qualified moisturizing can be achieved only by being applied for many times.

Toner, also called toning lotion, is applied to skin for cleaning and mainly has the functions of restoring pH value, conditioning horny layer and supplementing water. The moisturizing and water-locking performances of the existing toner are not ideal.

Disclosure of Invention

The invention aims to provide the moisturizing essence toner, the biological carbohydrate gum-1 can improve the skin immunity and the oxidation resistance, and is cooperated with other components to obviously improve the phenomenon of dry and water shortage of the skin, enhance the moisturizing and moisturizing capabilities of the skin, and achieve the effects of moisturizing the skin, improving the skin quality, keeping moisture for a long time and the like, and the biological carbohydrate gum-1 is modified to have better moisturizing property and improve the whitening and anti-aging properties.

The technical scheme of the invention is realized as follows:

the invention provides moisturizing essence toner which is prepared from the following raw materials: dipotassium glycyrrhizinate, glycerol, glyceryl polyether-26, 1, 2-propylene glycol, PEG-5 glyceryl stearate, polysorbate-60, polyglutamic acid, biological polysaccharide humectant, EDTA disodium, antiseptic and water.

As a further improvement of the invention, the moisturizing essence toner is prepared from the following raw materials in percentage by weight:

dipotassium glycyrrhizinate 0.02-0.08%;

0.5-3.5% of glyceryl polyether;

0.2 to 0.6 percent of PEG-5 glyceryl stearate;

polysorbate-60.1-0.5%;

4.0 to 8.0 percent of biological polysaccharide humectant;

0.02-0.08% of EDTA disodium;

0.03-0.07% of nisin;

the balance being water.

In the formula, dipotassium glycyrrhizinate is used as an astringent. Glyceryl polyether-26 and humectant. PEG-5 glyceryl stearate and emulsifier. Polysorbate-60 and emulsifier. Disodium EDTA, chelating agent. The nisin is a preservative.

The biological polysaccharide humectant is biological carbohydrate gum-1 (CAS No. 194237-89-3) and/or hydrolyzed sclerotium rolfsii gum (CAS No. 39464-87-4). Preferably, the biological polysaccharide humectant is a mixture of biological carbohydrate gum-1 and hydrolyzed sclerotium rolfsii gum according to the mass ratio of (1-6) to 1; preferably, (2-4): 1, preferably, 3.

The biological polysaccharide gum-1 and the hydrolyzed sclerotium rolfsii gum have obvious effects of moisturizing and supplementing water, the biological polysaccharide gum-1 contains polysaccharide with high molecular weight, so the water absorption and moisturizing effects of the biological polysaccharide gum are enhanced, the biological polysaccharide gum is easier to degrade into small molecular sugar by skin cells to naturally capture water molecules, the skin barrier repair can be accelerated and the percutaneous water loss can be reduced due to the fact that the biological polysaccharide gum contains fucose, the hydrolyzed sclerotium rolfsii gum is a novel nonionic salt-resistant and temperature-resistant biological polysaccharide polymer-scleroglucan produced by sclerotium rolfsii, the scleroglucan is a natural capsule-shaped glucan, the biological polysaccharide gum-1 and the hydrolyzed sclerotium rolfsii gum are mixed and compounded, the two biological polysaccharides are mutually wound, the obtained high molecular polysaccharide locks water and is difficult to volatilize and dissipate, and the moisturizing effect can be obviously improved.

Furthermore, the invention modifies the biological carbohydrate gum-1 to further improve the performance. The biological carbohydrate gum-1 can improve the immunity and the oxidation resistance of the skin, is cooperated with other components, obviously improves the phenomenon of dry and water-deficient skin, enhances the water replenishing and moisturizing capability of the skin, achieves the effects of moisturizing the skin, improving the skin quality, long-acting and efficient moisturizing and the like, and has better moisturizing property, and the whitening and anti-aging performance after the biological carbohydrate gum-1 is modified.

The modified biological sugar gum-1 is prepared by the following method:

dissolving 1 weight part of biological carbohydrate gum-1 in NaOH aqueous solution, adding 0.5-3 weight parts of modifier p-methylbenzenesulfonyl chloride and/or acetic anhydride, controlling the pH value of a reaction solution to be 8.0-8.5, and reacting for 1-3 hours;

adjusting the pH value of the reaction solution to 7.0, and centrifuging to obtain a supernatant;

and drying the supernatant to constant weight to obtain the modified biological carbohydrate gum-1.

Further, the modified biological sugar gum-1 is prepared by the following method:

dissolving 1 weight part of bioglycan-1 in 30-50 weight parts of NaOH aqueous solution with pH of 9.0-10.0 at 20-25 ℃, adding 0.5-3 weight parts of modifier p-toluenesulfonyl chloride and/or acetic anhydride, dropwise adding NaOH aqueous solution with pH of 9.0-10.0 to control the pH of reaction liquid to be 8.0-8.5, and stirring for 10-30 minutes; reacting for 1-3 hours at 30-50 ℃;

naturally cooling to 20-25 ℃, dropwise adding 0.5-2mol/L HCl aqueous solution until the pH value of the reaction solution is 7.0, centrifuging at 3000-4000r/min for 5-15 minutes to remove insoluble substances to obtain supernatant;

and drying the supernatant at 80-100 ℃ to constant weight to obtain the modified biological carbohydrate gum-1.

Further, the modifier is p-methyl benzene sulfonyl chloride and acetic anhydride according to a mass ratio of 1: (3-6), preferably 1.

The invention adopts acetylation modification by acetic anhydride method or sulfonylation modification by p-methyl benzene sulfonyl chloride method, which can effectively improve the moisture absorption/retention capacity, and the acetylation modification by acetic anhydride method is better than the sulfonylation modification by p-methyl benzene sulfonyl chloride method. Furthermore, the combined treatment of acetylation modification by an acetic anhydride method and sulfonylation modification by a p-methylbenzenesulfonyl chloride method is adopted, so that the in-vitro oxidation resistance and moisture absorption/retention capacity of the laminarin can be greatly improved, the two have synergistic interaction, and the mechanism is yet to be researched.

Further preferably, the biological polysaccharide humectant is a mixture of modified biological carbohydrate gum-1 and hydrolyzed sclerotium rolfsii gum according to a mass ratio of (1-6) to 1; preferably, (2-4) 1, preferably, 3.

The moisturizing essence toner is prepared by a general method in the cosmetic industry, for example, dipotassium glycyrrhizinate, glyceryl polyether-26, PEG-5 glyceryl stearate, polysorbate-60, a biological polysaccharide humectant, EDTA disodium and a preservative are directly dissolved in water at 40-60 ℃, stirred and mixed uniformly, and then the moisturizing essence toner is obtained after standing, cooling and filtering.

The moisturizing essence toner disclosed by the invention can effectively remove dirt and oily secretion on the skin, and keep the stratum corneum of the skin to be soft and moist by moderate moisture.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be obtained by a person skilled in the art without making any creative effort based on the embodiments in the present invention, belong to the protection scope of the present invention.

The biological sugar gum-1 is selected from SYT-202001 biological sugar gum-1 available from Guangzhou Ansheng Fine chemical engineering Co. Acetic anhydride CAS number 108-24-7, p-methylbenzenesulfonyl chloride CAS number 98-59-9. The hydrolyzed sclerotium rolfsii gum is prepared from hydrolyzed sclerotium rolfsii gum provided by Guangzhou Jiahang biological technology limited company.

Example 1 preparation of modified biogel Gum-1

Dissolving 1 weight part of bioglycan-1 in 40 weight parts of NaOH aqueous solution with pH of 9.5 at 20 ℃, adding 2 weight parts of modifier p-toluenesulfonyl chloride, dropwise adding the NaOH aqueous solution with pH of 9.5 to control the pH of the reaction solution to be 8.5, and stirring for 20 minutes; reacting for 2 hours at 40 ℃;

naturally cooling to 20 ℃, dropwise adding 1mol/L HCl aqueous solution until the pH value of the reaction solution is 7.0, centrifuging at 3500r/min for 10 minutes, and removing insoluble substances to obtain supernatant;

and drying the supernatant at 90 ℃ to constant weight to obtain the modified biological sugar gum-1.

EXAMPLE 2 preparation of modified biosaccharide gum-1

Dissolving 1 weight part of bioglycan gum-1 in 40 weight parts of NaOH aqueous solution with pH of 9.5 at 20 ℃, adding 2 weight parts of modifier acetic anhydride, dropwise adding NaOH aqueous solution with pH of 9.5 to control the pH of reaction liquid to be 8.5, and stirring for 20 minutes; reacting for 2 hours at 40 ℃;

EXAMPLE 3 preparation of modified biosaccharide gum-1

Dissolving 1 weight part of bioglycan gum-1 in 40 weight parts of NaOH aqueous solution with pH of 9.5 at 20 ℃, adding 0.4 weight part of modifier p-toluenesulfonyl chloride and 1.6 weight parts of modifier acetic anhydride, dropwise adding NaOH aqueous solution with pH of 9.5 to control the pH of reaction liquid to be 8.5, and stirring for 20 minutes; reacting at 40 ℃ for 2 hours;

Example 4 preparation of moisturizing essence toner

The moisturizing essence toner is prepared from the following raw materials in percentage by weight:

the biological polysaccharide humectant is biological carbohydrate gum-1.

Dissolving dipotassium glycyrrhizinate, glyceryl polyether-26, PEG-5 glyceryl stearate, polysorbate-60, biological polysaccharide humectant, EDTA disodium and preservative in water at 50 ℃, stirring and mixing uniformly, standing, cooling, filtering and filling to obtain the moisturizing essence toner.

Example 5 preparation of moisturizing essence toner

the biological polysaccharide humectant is hydrolyzed sclerotium rolfsii gum.

At 50 ℃, dissolving dipotassium glycyrrhizinate, glyceryl polyether-26, PEG-5 glyceryl stearate, polysorbate-60, biological polysaccharide humectant, EDTA disodium and preservative in water, stirring and mixing uniformly, standing, cooling, filtering and filling to obtain the moisturizing essence toner.

Example 6 preparation of moisturizing essence toner

the biological polysaccharide humectant is the modified biological carbohydrate gum-1 prepared in example 1.

Example 7 preparation of moisturizing essence toner

the biological polysaccharide humectant is the modified biological carbohydrate gum-1 prepared in example 2.

Example 8 preparation of moisturizing essence toner

the biological polysaccharide humectant is a mixture of biological carbohydrate gum-1 and hydrolyzed sclerotium rolfsii gum in a mass ratio of 3.

Example 9 preparation of moisturizing essence toner

the biological polysaccharide humectant is the modified biological carbohydrate gum-1 prepared in example 3.

Example 10 preparation of moisturizing essence toner

the biological polysaccharide humectant is a mixture of the modified biological carbohydrate gum-1 prepared in the example 3 and the hydrolyzed sclerotium rolfsii gum in a mass ratio of 3.

Test example 1

After the facial skin was cleaned with a face wash, dried, 2 grams of moisturizing essence toner was evenly applied to the face, and the facial skin was tapped for 30 seconds.

After the face is naturally dried, the moisture content A of the face skin is measured by a skin detector under the condition of room temperature 25 ℃ and humidity 60%. And (4) standing and sitting indoors for 1 hour, measuring the moisture content B of the facial skin again under the same condition, and calculating the moisture retention rate, wherein the higher the moisture retention rate is, the more excellent the water retention property is.

Each group was tested by selecting 10 healthy skin women as the test subjects and taking the average value. After comparison, statistical analysis is carried out, and the comparison results of all groups show that P is less than 0.05, and the difference has statistical significance.

Moisture retention = B ÷ a × 100%.

Table 1: water retention of facial skin

	Water retention of facial skin,%
		Example 4	68.4
Example 5	72.5
		Example 6	74.8
Example 7	75.3
		Example 8	81.2
Example 9	83.7
		Example 10	88.5

Furthermore, the invention adopts acetylation modification by an acetic anhydride method or sulfonylation modification by a p-methyl benzene sulfonyl chloride method, both of which can effectively improve the moisture absorption/retention capacity, and the acetylation modification by the acetic anhydride method is better than the sulfonylation modification by the p-methyl benzene sulfonyl chloride method. Furthermore, the acetic anhydride method acetylation modification and the p-methyl benzene sulfonyl chloride method sulfonylation modification are combined for treatment, so that the in-vitro oxidation resistance and the moisture absorption/retention capacity of the laminarin can be greatly improved, the two synergistically enhance the effects of obviously improving the phenomenon of skin dryness and water shortage, enhancing the water and moisture retention capacity of the skin, and achieving the effects of moistening the skin, improving the skin quality, long-acting high-efficiency moisture retention and the like, and the biological carbohydrate gum-1 is modified to have better moisture retention and improve the whitening and anti-aging performance.

The above description is only for the purpose of illustrating the preferred embodiments of the present invention and should not be taken as limiting the scope of the present invention, which is intended to cover any modifications, equivalents, improvements, etc. within the spirit and scope of the present invention.

Claims

1. The moisturizing essence toner is characterized by being prepared from the following raw materials:

dipotassium glycyrrhizinate 0.02-0.08%;

0.5-3.5% of glyceryl polyether;

PEG-5 glyceryl stearate 0.2-0.6%;

polysorbate-60.1-0.5%;

4.0 to 8.0 percent of biological polysaccharide humectant;

0.02-0.08% of EDTA disodium;

0.03-0.07% of nisin;

the balance of water;

the biological polysaccharide humectant is a mixture of modified biological carbohydrate gum-1 and hydrolyzed sclerotium rolfsii gum according to the mass ratio of 3;

the modified biological sugar gum-1 is prepared by the following method: