CN111643596A - A Chinese medicinal composition for treating diabetes, and its preparation method - Google Patents
A Chinese medicinal composition for treating diabetes, and its preparation method Download PDFInfo
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
Abstract
The invention provides a traditional Chinese medicine composition for treating diabetes and a preparation method thereof, relating to the technical field of traditional Chinese medicine, the raw materials comprise rhizoma polygonati, herba cistanche, radix polygoni multiflori preparata, fructus rosae laevigatae, rhizoma dioscoreae, radix paeoniae rubra, hawthorn, fructus schizandrae 10, fingered citron and mixed extracts, (1) the raw materials are weighed according to the weight proportion; (2) drying the raw materials, and grinding into powder; (3) preparing a mixed extract; (4) mixing the wall-broken ganoderma lucidum spore powder with the mixed extract to obtain a mixture A: (5) pouring the raw material powder into the mixture A (6) and preparing into tablets. The sealwort, the cistanche, the prepared fleece flower root, the cherokee rose fruit, the Chinese yam, the red paeony root, the Chinese magnoliavine fruit and the fingered citron are used as the medicines to strengthen the spleen and replenish qi, clear away heat and toxic material and effectively reduce the blood sugar.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating diabetes and a preparation method thereof.
Background
Diabetes is a group of metabolic diseases characterized by hyperglycemia. Hyperglycemia is caused by a defect in insulin secretion or an impaired biological action, or both. Hyperglycemia, which is a long-standing cause of chronic damage to, and dysfunction of, various tissues, particularly the eye, kidney, heart, blood vessels, and nerves.
On one hand, the sugar content in blood of a diabetic is overproof, on the other hand, the sugar content in cells is lack, and the required nutrition cannot enter the cells, so that the diabetes is caused. Patients with diabetes are tired and weak, have emaciation, and are easy to have scabies and various inflammations of respiratory and urinary biliary systems. The traditional Chinese medicine and the western medicine for treating diabetes at present are various in variety, the western medicine has obvious blood sugar reducing effect, but the side effect of long-term administration of the traditional Chinese medicine and the western medicine can cause damage to the stomach, the liver and the kidney and cause dependence of patients, while the traditional Chinese medicine has no toxic or side effect and no dependence after long-term administration, but the blood sugar reducing effect is not obvious and the curative effect is unstable, particularly aiming at type II diabetes, the traditional Chinese medicine and the western medicine which are only blood sugar reducing type have unsatisfactory curative effect, the pathogeny cannot be thoroughly removed, and the purpose of completely.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine composition for treating diabetes to solve the technical problems.
In order to solve the technical problems, the invention adopts the following technical scheme:
a traditional Chinese medicine composition for treating diabetes is characterized in that: the feed is prepared from the following raw materials in parts by weight:
10-30 parts of rhizoma polygonati, 10-20 parts of cistanche, 10-20 parts of radix polygoni multiflori preparata, 10-20 parts of cherokee rose fruit, 10-20 parts of Chinese yam, 5-15 parts of red peony root, 5-15 parts of hawthorn, 10-20 parts of schisandra chinensis, 10-20 parts of fingered citron and 30-40 parts of mixed extract.
Preferably, the traditional Chinese medicine composition comprises 20 parts of rhizoma polygonati, 15 parts of cistanche, 15 parts of radix polygoni multiflori preparata, 15 parts of cherokee rose fruit, 15 parts of Chinese yam, 10 parts of red peony root, 10 parts of hawthorn, 15 parts of schisandra chinensis, 15 parts of fingered citron and 35 parts of mixed extract.
Preferably, the mixed extract comprises wall-broken ganoderma lucidum spore powder, ganoderma lucidum extract, inonotus obliquus extract, mulberry leaf extract and grifola frondosa extract.
Preferably, the wall-broken ganoderma lucidum spore powder is superfine powder obtained by wall breaking of ganoderma lucidum spores.
Preferably, the wall-broken ganoderma lucidum spore powder, the ganoderma lucidum extract, the inonotus obliquus extract, the mulberry leaf extract and the grifola frondosa extract are prepared from the following components in percentage by weight: and (3) ganoderma lucidum extract: inonotus obliquus extract: and (3) mulberry leaf extract: maitake mushroom extract = 1.5: 1: 2: 2: 1.
a preparation method of a traditional Chinese medicine composition for treating diabetes is characterized by comprising the following steps: the method comprises the following steps:
(1) weighing rhizoma Polygonati, Cistanchis herba, radix Polygoni Multiflori Preparata, fructus Rosae Laevigatae, rhizoma Dioscoreae, radix Paeoniae Rubra, fructus crataegi, fructus Schisandrae chinensis and fructus Citri Sarcodactylis according to weight ratio;
(2) drying all the raw materials in the step (1), and then grinding into powder;
(3) crushing lucid ganoderma, inonotus obliquus, mulberry leaves and grifola frondosa, leaching for 40-50 h by using ethanol water solution with volume concentration of 65-75%, filtering to obtain filtrate, and concentrating the filtrate to obtain extract;
(4) fully stirring and mixing the wall-broken ganoderma lucidum spore powder and the extract in the step (3) to obtain a mixture A;
(5) pouring rhizoma Polygonati, Cistanchis herba, radix Polygoni Multiflori Preparata, fructus Rosae Laevigatae, rhizoma Dioscoreae, radix Paeoniae Rubra, fructus Schisandrae chinensis and fructus Citri Sarcodactylis into mixture A, and stirring to obtain viscous mixture B;
(6) preparing the mixture B into tablets, granules, capsules or pills, and then uniformly spraying the hawthorn powder on the outer surface of the prepared medicament;
(7) and (3) conveying the prepared medicament into a drying oven for drying, and removing moisture to obtain the final traditional Chinese medicine composition.
Preferably, when drying in the step (7), the drying temperature is 50-70 ℃, and the drying time is 30-50 min.
Preferably, the relative density of the extract prepared in the step (3) is 1.1-1.15.
Preferably, the sealwort is made from root position as raw material.
The invention has the beneficial effects that:
the medicinal composition of the invention takes sealwort, desertliving cistanche, prepared fleece flower root, cherokee rose fruit, Chinese yam, red paeony root, Chinese magnoliavine fruit and finger citron as medicines, has the effects of strengthening spleen, supplementing qi, clearing heat and removing toxicity, can effectively play the role of reducing blood sugar, has better curative effect on treating diabetes by the effective matching of monarch, minister, assistant and guide, can also facilitate the swallowing of the medicament by arranging hawthorn, eliminating food retention, tonifying spleen and wrapping the hawthorn on the outer surface of the medicament, takes lucid ganoderma and lucid ganoderma spore powder with wall broken as monarch medicines, inonotus obliquus betulina as minister medicines, mulberry leaves as assistant medicines and grifola frondosa as guide medicines by adding mixed extracts, has the characteristics of reasonable formula, combination of all medicines, effective reduction of blood sugar content and enhancement of the immunity of a diabetic patient, can repair and improve the pancreas function to a certain degree, has obvious effect on promoting the recovery of diabetes, has no toxic or side effect on the human body, the components of the whole preparation are matched with each other, so that the blood sugar can be reduced, other complications caused by diabetes can be relieved, the diabetic can recover normal life, and the preparation method has good application prospect in the field of diabetes rehabilitation.
And (3) pharmacological and medicinal property analysis:
rhizoma polygonati: sweet, neutral and non-toxic. Tonify middle energizer and qi, expel wind-damp, and calm five zang organs.
Cistanche deserticola is sweet, mild and nontoxic. The five strains damage seven organs, tonify the middle-jiao, nourish the five fu-organs, strengthen yin and nourish essence.
Radix Polygoni Multiflori Preparata is bitter, sweet, astringent and slightly warm. It enters liver, heart and kidney meridians. Nourishing liver and kidney, replenishing essence and blood, blackening beard and hair, strengthening bones and muscles,
the cherokee rose fruit is sour, astringent and flat and has no toxicity. The spleen draining diarrhea and astringing essence.
The Chinese yam is sweet, warm, flat and nontoxic. Deficiency, cold and heat, pathogenic qi, middle warmer, qi and force, muscle growth, and yin tonification.
Red peony root: bitter and slightly cold. Entering liver meridian, nourishing yin, removing blood stasis, relieving pain, cooling blood, and relieving swelling
Hawthorn fruit: acid, cold and non-toxic. Promote digestion, nourish the spleen.
Schisandra chinensis: acid, warm and non-toxic. Replenishing qi, relieving cough, invigorating qi, treating asthenia, treating emaciation, nourishing viscera, and treating asthenia
Fingered citron: has the functions of regulating qi, reducing phlegm, relieving vomit, relieving distension, soothing liver, strengthening spleen and harmonizing stomach.
The ganoderma lucidum and the wall-broken ganoderma lucidum spore powder can help effectively reduce blood sugar and avoid urine sugar, and are health-care food. Ganoderma lucidum, as a medicine, is originally recorded in Shen nong Ben Cao Jing, can moisten and reinforce the body, strengthen the body resistance and consolidate the constitution, prolong life, and has multiple effects of inhibiting tumor, improving immunity, reducing blood sugar, resisting oxidation and the like. Ganoderma belongs to the family Polyporaceae of Basidiomycetes, and Ganoderma spore is germ cell ejected from pileus of Ganoderma when Ganoderma grows mature, and is also called basidiospore. Ganoderma triterpene in Ganoderma and Ganoderma spore powder can enhance function of immune system, and also can effectively improve blood circulation of pancreas, stimulate insulin secretion, thereby improving physiological function of pancreas, and reducing blood sugar concentration; besides containing abundant terpenes, the health-care food also contains abundant microelements such as ganoderma lucidum polysaccharide, adenosine, amino acid and organic germanium, has the functions of resisting oxidation and clearing blood, and can effectively reduce the risk of diabetic patients for generating complications such as cardiovascular diseases.
Inonotus obliquus belongs to Aphyllophorales of Polyporaceae of Eumycota, contains plant fiber polysaccharide, inonotus obliquus essence, inonotus obliquus alcohol, various oxidized triterpenoids, tetanic acid, various lanosterol triterpenoids, folic acid derivatives, aromatic vanillic acid, syringic acid and gamma hydroxybenzoic acid, has effects of resisting cancer, lowering blood pressure, lowering blood sugar, reviving immunity, improving activity of immunocyte, inhibiting cancer cell diffusion and recurrence, preventing absorption of harmful substances such as carcinogen in stomach and intestine, and promoting excretion. It is reported that the cure rate of the refined powder of inonotus obliquus for diabetes reaches 93%, which can increase the supply of insulin and reduce the level of malonic acid of diabetic patients by eliminating free radicals and improving the micro-ecological environment, repairing damaged islet cells and pancreatic tissues.
The mulberry leaves contain abundant glycosidase inhibitor 1-Deoxynojirimycin (DNJ) and mulberry leaf polysaccharide, and the DNJ inhibits the activity of the saccharide clastic enzyme, so that the absorption of the disaccharide by the small intestine is inhibited, and the increase of fasting blood sugar and postprandial blood sugar is reduced; meanwhile, the mulberry leaf polysaccharide can also promote beta cells to secrete insulin, so that the utilization of sugar by cells, the synthesis of hepatic glycogen and the improvement of glycometabolism can be promoted, and the effect of reducing blood sugar is finally achieved; crude protein and amino acid in mulberry leaves can also stimulate the secretion of insulin, and can be used as a regulating factor for the secretion and release of insulin in vivo to reduce the speed of insulin decomposition; the organic chromium in folium Mori can relieve insulin resistance and enhance insulin function. In a word, the mulberry leaves contain various physiological active substances such as rich amino acids, dietary fibers, polysaccharides, vitamins, minerals and the like, have good blood sugar reducing effect, and also have various effects of reducing blood pressure and blood fat, delaying senility and the like.
Grifola frondosa belongs to Grifola of Polyporaceae, is rich in nutrition, and contains abundant proteins, carbohydrates, fibers, vitamins, multiple trace elements and biotin. Through a plurality of clinical experimental researches in the United states and Japan, the Grifola frondosa extract has the treatment effect on diabetes, can reduce the blood sugar of a hereditary diabetes mouse, can also reduce the levels of insulin and triglyceride in the plasma of the mouse, and has the effects of reducing blood fat and increasing fat metabolism. Additional experimental results indicate that the anti-diabetic effect of the resistor (grifolan) is through modulation of the metabolism of absorbed carbohydrates rather than through inhibition of enzymes or modulation of carbohydrate absorption on the intestinal mucosa.
Detailed Description
The present invention will be further described with reference to specific embodiments for the purpose of facilitating an understanding of technical means, characteristics of creation, objectives and functions realized by the present invention, but the following embodiments are only preferred embodiments of the present invention, and are not intended to be exhaustive. Based on the embodiments in the implementation, other embodiments obtained by those skilled in the art without any creative efforts belong to the protection scope of the present invention. The experimental methods in the following examples are conventional methods unless otherwise specified, and materials, reagents and the like used in the following examples are commercially available unless otherwise specified.
Example 1
A traditional Chinese medicine composition for treating diabetes is prepared from the following raw materials in parts by weight:
10 parts of rhizoma polygonati, 10 parts of cistanche, 10 parts of radix polygoni multiflori preparata, 10 parts of cherokee rose fruit, 10 parts of Chinese yam, 5 parts of red peony root, 5 parts of hawthorn, 10 parts of schisandra chinensis, 10 parts of fingered citron and 30 parts of mixed extract.
The mixed extract comprises wall-broken ganoderma lucidum spore powder, ganoderma lucidum extract, inonotus obliquus extract, mulberry leaf extract and grifola frondosa extract, wherein the wall-broken ganoderma lucidum spore powder comprises the following components in percentage by weight: and (3) ganoderma lucidum extract: inonotus obliquus extract: and (3) mulberry leaf extract: maitake mushroom extract = 1.5: 1: 2: 2: 1.
a preparation method of a traditional Chinese medicine composition for treating diabetes comprises the following steps:
(1) weighing rhizoma Polygonati, Cistanchis herba, radix Polygoni Multiflori Preparata, fructus Rosae Laevigatae, rhizoma Dioscoreae, radix Paeoniae Rubra, fructus crataegi, fructus Schisandrae chinensis and fructus Citri Sarcodactylis according to weight ratio;
(2) drying all the raw materials in the step (1), and then grinding into powder;
(3) crushing lucid ganoderma, inonotus obliquus, mulberry leaves and grifola frondosa, leaching for 40-50 h by using ethanol water solution with volume concentration of 65-75%, filtering to obtain filtrate, and concentrating the filtrate to obtain extract;
(4) fully stirring and mixing the wall-broken ganoderma lucidum spore powder and the extract in the step (3) to obtain a mixture A;
(5) pouring rhizoma Polygonati, Cistanchis herba, radix Polygoni Multiflori Preparata, fructus Rosae Laevigatae, rhizoma Dioscoreae, radix Paeoniae Rubra, fructus Schisandrae chinensis and fructus Citri Sarcodactylis into mixture A, and stirring to obtain viscous mixture B;
(6) preparing the mixture B into tablets, granules, capsules or pills, and then uniformly spraying the hawthorn powder on the outer surface of the prepared medicament;
(7) and (3) conveying the prepared medicament into a drying oven for drying, and removing moisture to obtain the final traditional Chinese medicine composition.
Example 2
A traditional Chinese medicine composition for treating diabetes is prepared from the following raw materials in parts by weight:
20 parts of rhizoma polygonati, 15 parts of cistanche, 15 parts of prepared fleece-flower root, 15 parts of cherokee rose fruit, 15 parts of Chinese yam, 10 parts of red peony root, 10 parts of hawthorn, 15 parts of schisandra fruit, 15 parts of fingered citron and 35 parts of mixed extract.
The mixed extract comprises wall-broken ganoderma lucidum spore powder, ganoderma lucidum extract, inonotus obliquus extract, mulberry leaf extract and grifola frondosa extract, wherein the wall-broken ganoderma lucidum spore powder comprises the following components in percentage by weight: and (3) ganoderma lucidum extract: inonotus obliquus extract: and (3) mulberry leaf extract: maitake mushroom extract = 1.5: 1: 2: 2: 1.
a preparation method of a traditional Chinese medicine composition for treating diabetes is characterized by comprising the following steps: the method comprises the following steps:
(1) weighing rhizoma Polygonati, Cistanchis herba, radix Polygoni Multiflori Preparata, fructus Rosae Laevigatae, rhizoma Dioscoreae, radix Paeoniae Rubra, fructus crataegi, fructus Schisandrae chinensis and fructus Citri Sarcodactylis according to weight ratio;
(2) drying all the raw materials in the step (1), and then grinding into powder;
(3) crushing lucid ganoderma, inonotus obliquus, mulberry leaves and grifola frondosa, leaching for 40-50 h by using ethanol water solution with volume concentration of 65-75%, filtering to obtain filtrate, and concentrating the filtrate to obtain extract;
(4) fully stirring and mixing the wall-broken ganoderma lucidum spore powder and the extract in the step (3) to obtain a mixture A;
(5) pouring rhizoma Polygonati, Cistanchis herba, radix Polygoni Multiflori Preparata, fructus Rosae Laevigatae, rhizoma Dioscoreae, radix Paeoniae Rubra, fructus Schisandrae chinensis and fructus Citri Sarcodactylis into mixture A, and stirring to obtain viscous mixture B;
(6) preparing the mixture B into tablets, granules, capsules or pills, and then uniformly spraying the hawthorn powder on the outer surface of the prepared medicament;
(7) and (3) conveying the prepared medicament into a drying oven for drying, and removing moisture to obtain the final traditional Chinese medicine composition.
Example 3
A traditional Chinese medicine composition for treating diabetes is prepared from the following raw materials in parts by weight:
30 parts of rhizoma polygonati, 20 parts of cistanche, 20 parts of prepared fleece-flower root, 20 parts of cherokee rose fruit, 20 parts of Chinese yam, 15 parts of red peony root, 15 parts of hawthorn, 20 parts of schisandra fruit, 20 parts of fingered citron and 40 parts of mixed extract.
The mixed extract comprises wall-broken ganoderma lucidum spore powder, ganoderma lucidum extract, inonotus obliquus extract, mulberry leaf extract and grifola frondosa extract, wherein the wall-broken ganoderma lucidum spore powder comprises the following components in percentage by weight: and (3) ganoderma lucidum extract: inonotus obliquus extract: and (3) mulberry leaf extract: maitake mushroom extract = 1.5: 1: 2: 2: 1.
a preparation method of a traditional Chinese medicine composition for treating diabetes is characterized by comprising the following steps: the method comprises the following steps:
(1) weighing rhizoma Polygonati, Cistanchis herba, radix Polygoni Multiflori Preparata, fructus Rosae Laevigatae, rhizoma Dioscoreae, radix Paeoniae Rubra, fructus crataegi, fructus Schisandrae chinensis and fructus Citri Sarcodactylis according to weight ratio;
(2) drying all the raw materials in the step (1), and then grinding into powder;
(3) crushing lucid ganoderma, inonotus obliquus, mulberry leaves and grifola frondosa, leaching for 40-50 h by using ethanol water solution with volume concentration of 65-75%, filtering to obtain filtrate, and concentrating the filtrate to obtain extract;
(4) fully stirring and mixing the wall-broken ganoderma lucidum spore powder and the extract in the step (3) to obtain a mixture A;
(5) pouring rhizoma Polygonati, Cistanchis herba, radix Polygoni Multiflori Preparata, fructus Rosae Laevigatae, rhizoma Dioscoreae, radix Paeoniae Rubra, fructus Schisandrae chinensis and fructus Citri Sarcodactylis into mixture A, and stirring to obtain viscous mixture B;
(6) preparing the mixture B into tablets, granules, capsules or pills, and then uniformly spraying the hawthorn powder on the outer surface of the prepared medicament;
(7) and (3) conveying the prepared medicament into a drying oven for drying, and removing moisture to obtain the final traditional Chinese medicine composition.
Example 4
A traditional Chinese medicine composition for treating diabetes is prepared from the following raw materials in parts by weight:
20 parts of rhizoma polygonati, 15 parts of cistanche, 15 parts of prepared fleece-flower root, 15 parts of cherokee rose fruit, 15 parts of Chinese yam, 10 parts of red peony root, 10 parts of hawthorn, 15 parts of schisandra chinensis and 15 parts of fingered citron.
A preparation method of a traditional Chinese medicine composition for treating diabetes is characterized by comprising the following steps: the method comprises the following steps:
(1) weighing rhizoma Polygonati, Cistanchis herba, radix Polygoni Multiflori Preparata, fructus Rosae Laevigatae, rhizoma Dioscoreae, radix Paeoniae Rubra, fructus crataegi, fructus Schisandrae chinensis and fructus Citri Sarcodactylis according to weight ratio;
(2) drying all the raw materials in the step (1), and then grinding into powder;
(5) adding water into rhizoma Polygonati, Cistanchis herba, radix Polygoni Multiflori Preparata, fructus Rosae Laevigatae, rhizoma Dioscoreae, radix Paeoniae Rubra, fructus Schisandrae chinensis and fructus Citri Sarcodactylis, and stirring to obtain viscous mixture B;
(6) preparing the mixture B into tablets, granules, capsules or pills, and then uniformly spraying the hawthorn powder on the outer surface of the prepared medicament;
(7) and (3) conveying the prepared medicament into a drying oven for drying, and removing moisture to obtain the final traditional Chinese medicine composition.
Example 5
A traditional Chinese medicine composition for treating diabetes is prepared from the following raw materials in parts by weight:
35 parts of mixed extract, wherein the mixed extract comprises wall-broken ganoderma lucidum spore powder, a ganoderma lucidum extract, an inonotus obliquus extract, a mulberry leaf extract and a grifola frondosa extract, and the wall-broken ganoderma lucidum spore powder comprises the following components in parts by weight: and (3) ganoderma lucidum extract: inonotus obliquus extract: and (3) mulberry leaf extract: maitake mushroom extract = 1.5: 1: 2: 2: 1.
a preparation method of a traditional Chinese medicine composition for treating diabetes comprises the following steps:
(1) crushing lucid ganoderma, inonotus obliquus, mulberry leaves and grifola frondosa, leaching for 40-50 h by using ethanol water solution with volume concentration of 65-75%, filtering to obtain filtrate, and concentrating the filtrate to obtain extract;
(2) fully stirring and mixing the wall-broken ganoderma lucidum spore powder and the extract in the step (3) to obtain a mixture A;
(6) preparing the mixture A into tablets, granules, capsules or pills;
(7) and (3) conveying the prepared medicament into a drying oven for drying, and removing moisture to obtain the final traditional Chinese medicine composition.
Example analysis:
in examples 1 to 3, the starting materials used were all the same, but the amounts of the starting materials were varied;
example 4 compared to example 2, no mixed extract was added to example 4;
compared with the embodiment 2, in the embodiment 5, the raw materials of rhizoma polygonati, herba cistanche, radix polygoni multiflori preparata, fructus rosae laevigatae, rhizoma dioscoreae, radix paeoniae rubra, hawthorn, fructus schizandrae and fingered citron are not added.
Acute toxicity test: the method comprises the following steps of taking 10 mice, randomly selecting the sex of the mice, dividing the mice into 5 groups, feeding the traditional Chinese medicine composition produced in the embodiment 1-5 to the mice of each group, continuously gavage the mice for one week twice a day with the gavage volume of 15ml/kg, and continuously observing the mice for 7 days without death.
Examples of clinical experiments
The preparation prepared in the embodiment 2 of the invention is taken as an example to explain the efficacy, the honeyed pill is clinically taken and orally taken, 2 times a day and 8-10 g each time, 300 patients with diabetes are treated, and the honeyed pill is continuously taken for 40-70 days. 294 cases are cured, 300 cases are clinically and obviously effective, 0 case is ineffective, and the overall cure rate reaches 98 percent. Follow-up visit was continued for 12 months with no recurrence.
Case 1
Li Jie, Jiangxi Nanchang, 60 years old, male. After the disease is suffered for 7 years, the blood sugar is 11-13mmol/L, and the improvement of taking traditional Chinese medicines and western medicines is not realized all the time. After the traditional Chinese medicine composition is tried to be eaten for 10 days, the blood sugar is reduced by 9 to 10.5mmol/L, and after the traditional Chinese medicine composition is eaten for one month, the blood sugar is reduced by 5.2 to 5.9 mmol/L. After one year, the call returns, all physical indexes are good, and the disease does not relapse until now.
Case 2
Zhangqi, Jiangxi Nanchang, age 52 years old, male. For patients with diabetes, the blood sugar is 10-12mmol/L for more than three years, and the improvement of taking traditional Chinese medicines and western medicines by seeking medical advice is not seen. After the traditional Chinese medicine composition is tried to be eaten for 10 days, the blood sugar is reduced by 9-11mmol/L, and then the blood sugar is reduced by 5.4-6.0mmol/L after the traditional Chinese medicine composition is insisted to be eaten for one month. After one year, the call returns, all physical indexes are good, and the disease does not relapse until now.
Case 3
Liu somewhere Yun, Anhui Hefei, 48 years old and male. For patients with diabetes, the blood sugar is 9-11mmol/L for more than four years, and the improvement of taking traditional Chinese medicines and western medicines by seeking medical doctors is not seen. After the traditional Chinese medicine composition is tried to be eaten for 10 days, the blood sugar is reduced by 8-10mmol/L, and then the blood sugar is reduced by 5.4-9.2mmol/L after the traditional Chinese medicine composition is eaten for 30 days. After one year, the call returns, all physical indexes are good, and the disease does not relapse until now.
Case 4
Chen and an Xie are good, 53 years old and male. The blood sugar of the patients with diabetes is 8.7-11mmol/L for more than five years, and the improvement of the traditional Chinese medicine and the western medicine is not seen all the time. After the traditional Chinese medicine composition is tried to be eaten for 10 days, the blood sugar is reduced by 7.6 to 9.5mmol/L, and then the blood sugar is reduced by 5.4 to 6.0mmol/L after the traditional Chinese medicine composition is eaten for 30 days. After one year, the call returns, all physical indexes are good, and the disease does not relapse until now.
In the above concrete cases, a plurality of actual cases prove that the traditional Chinese medicine composition has good curative effect, high cure rate of 98 percent and low recurrence rate when being used for treating diabetes. The traditional Chinese medicine composition has good treatment effect on diabetes of various degrees and has high cure rate.
The foregoing shows and describes the general principles, essential features, and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, and the preferred embodiments of the present invention are described in the above embodiments and the description, and are not intended to limit the present invention. The scope of the invention is defined by the appended claims and equivalents thereof.
Claims (9)
1. A traditional Chinese medicine composition for treating diabetes is characterized in that: the feed is prepared from the following raw materials in parts by weight:
10 to 30 parts of rhizoma polygonati, 10 to 20 parts of cistanche, 10 to 20 parts of radix polygoni multiflori preparata, 10 to 20 parts of cherokee rose fruit, 10 to 20 parts of Chinese yam, 5 to 15 parts of red peony root, 5 to 15 parts of hawthorn, 10 to 20 parts of schisandra chinensis, 10 to 20 parts of fingered citron and 30 to 40 parts of mixed extract.
2. The traditional Chinese medicine composition for treating diabetes according to claim 1, characterized in that: 20 parts of rhizoma polygonati, 15 parts of cistanche, 15 parts of prepared fleece-flower root, 15 parts of cherokee rose fruit, 15 parts of Chinese yam, 10 parts of red peony root, 10 parts of hawthorn, 15 parts of schisandra chinensis, 15 parts of fingered citron and 35 parts of mixed extract.
3. The traditional Chinese medicine composition for treating diabetes according to claim 1, characterized in that: the mixed extract comprises wall-broken ganoderma lucidum spore powder, ganoderma lucidum extract, inonotus obliquus extract, mulberry leaf extract and grifola frondosa extract.
4. The traditional Chinese medicine composition for treating diabetes according to claim 1, characterized in that: the wall-broken ganoderma lucidum spore powder is superfine powder obtained by wall breaking ganoderma lucidum spores.
5. The traditional Chinese medicine composition for treating diabetes according to claim 1, characterized in that: the wall-broken ganoderma lucidum spore powder, the ganoderma lucidum extract, the inonotus obliquus extract, the mulberry leaf extract and the grifola frondosa extract are prepared from the following components in parts by weight: and (3) ganoderma lucidum extract: inonotus obliquus extract: and (3) mulberry leaf extract: maitake mushroom extract = 1.5: 1: 2: 2: 1.
6. a method for preparing the traditional Chinese medicine composition for treating diabetes mellitus of claim 1, which is characterized by comprising the following steps: the method comprises the following steps:
(1) weighing rhizoma Polygonati, Cistanchis herba, radix Polygoni Multiflori Preparata, fructus Rosae Laevigatae, rhizoma Dioscoreae, radix Paeoniae Rubra, fructus crataegi, fructus Schisandrae chinensis and fructus Citri Sarcodactylis according to weight ratio;
(2) drying all the raw materials in the step (1), and then grinding into powder;
(3) crushing lucid ganoderma, inonotus obliquus, mulberry leaves and grifola frondosa, leaching for 40-50 h by using ethanol water solution with volume concentration of 65-75%, filtering to obtain filtrate, and concentrating the filtrate to obtain extract;
(4) fully stirring and mixing the wall-broken ganoderma lucidum spore powder and the extract in the step (3) to obtain a mixture A;
(5) pouring rhizoma Polygonati, Cistanchis herba, radix Polygoni Multiflori Preparata, fructus Rosae Laevigatae, rhizoma Dioscoreae, radix Paeoniae Rubra, fructus Schisandrae chinensis and fructus Citri Sarcodactylis into mixture A, and stirring to obtain viscous mixture B;
(6) preparing the mixture B into tablets, granules, capsules or pills, and then uniformly spraying the hawthorn powder on the outer surface of the prepared medicament;
(7) and (3) conveying the prepared medicament into a drying oven for drying, and removing moisture to obtain the final traditional Chinese medicine composition.
7. The preparation method of the traditional Chinese medicine composition for treating diabetes according to claim 7, characterized in that: and (3) when drying in the step (7), the drying temperature is 50-70 ℃, and the drying time is 30-50 min.
8. The preparation method of the traditional Chinese medicine composition for treating diabetes according to claim 7, characterized in that: the relative density of the extract prepared in the step (3) is 1.1-1.15.
9. The traditional Chinese medicine composition for treating diabetes according to claim 1, characterized in that: the sealwort adopts root position as raw material.
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| CN112704693A (en) * | 2020-12-31 | 2021-04-27 | 吴杰 | A Chinese medicinal extract composition for preventing and treating diabetes |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104288527A (en) * | 2014-11-04 | 2015-01-21 | 王松华 | Traditional Chinese medicinal composition for treating diabetes and preparation method and application thereof |
| CN106806643A (en) * | 2017-01-23 | 2017-06-09 | 邹玉华 | A kind of Chinese medicine composition for treating diabetes |
| CN108815230A (en) * | 2018-08-29 | 2018-11-16 | 常德市永春堂生物科技有限公司 | Chinese medicine composition and its preparation method and application for treating diabetes |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104288527A (en) * | 2014-11-04 | 2015-01-21 | 王松华 | Traditional Chinese medicinal composition for treating diabetes and preparation method and application thereof |
| CN106806643A (en) * | 2017-01-23 | 2017-06-09 | 邹玉华 | A kind of Chinese medicine composition for treating diabetes |
| CN108815230A (en) * | 2018-08-29 | 2018-11-16 | 常德市永春堂生物科技有限公司 | Chinese medicine composition and its preparation method and application for treating diabetes |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN112704693A (en) * | 2020-12-31 | 2021-04-27 | 吴杰 | A Chinese medicinal extract composition for preventing and treating diabetes |
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Application publication date: 20200911 |