CN111617103A - Silver ion graphene oxide-containing antibacterial and disinfectant protective cleaning solution - Google Patents
Silver ion graphene oxide-containing antibacterial and disinfectant protective cleaning solution Download PDFInfo
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Abstract
The invention discloses a protective cleaning solution containing silver ion graphene oxide for antibiosis and disinfection, a preparation method and application thereof, wherein the protective cleaning solution comprises the following components in percentage by mass: the protective cleaning solution comprises, by weight, 3.0-20.0% of cocamidopropyl betaine, 1.0-3.0% of glycerol, 1.0-10.0% of propylene glycol, 0.1-0.5% of carbomer, 0.1-0.5% of potassium hydroxide, 0.05-0.2% of hyaluronic acid, and the balance of silver ion solution, graphene oxide dispersion solution and water, wherein the dosage of the silver ion solution is 0.05-5.0ppm of the concentration of the protective cleaning solution, and the dosage of the graphene oxide dispersion solution is 0.1-3.0ppm of the concentration of the protective cleaning solution.
Description
Technical Field
The invention relates to the technical field of medicines, and particularly relates to a protective cleaning solution containing silver ions and graphene oxide for antibiosis and disinfection.
Background
The global new coronavirus epidemic situation outbreak in early spring 2020 brings huge challenges and serious injuries to the public health protection system of the society, immeasurable economic losses are brought to the society, the environmental protection and personal protection face great gaps, particularly, only local protection measures such as masks and hand washing disinfectant are adopted on the personal protection of the common people, and no corresponding protection articles are used for protecting the parts such as limbs, faces and hair exposed outside.
Traditional antiseptic solution for antibiosis often kills bacteria through the chemical reaction principle of antibacterial raw materials, and the drawback is that harm of different degrees is caused to human body, for example, harm of skin mucous membrane, symptom of digestive system, symptom of circulatory system and harm of nervous system:
firstly, the harm of the disinfection solution to human skin can burn the skin mucosa, so that the skin mucosa has the harm of red, swelling, heat, pain, damaged epidermis and the like.
Secondly, the digestive system is particularly remarkable, for example, the severe burning sensation and spastic pain of the esophagus, such as acid regurgitation, heartburn, nausea, vomiting and abdominal colic, are caused by drinking the sterile water by mistake, and the periumbilical colic and the whole abdominal colic are remarkable, and occasionally, diarrhea, black stool or hematemesis and other conditions can occur to patients.
Thirdly, the damage to the circulatory system may be symptoms such as arrhythmia, tachycardia, chest distress, short breath, and precordial discomfort.
Fourth, damage to the nervous system can irritate the central and peripheral nervous systems, causing dizziness, headache, disorientation, and different symptoms of the pyramidal and extrapyramidal systems.
Disclosure of Invention
Technical problem to be solved
In order to overcome the defects of the prior art, the protective cleaning solution containing silver ion graphene oxide antibacterial disinfection is provided, the physical disinfection technology of silver ion graphene oxide antibacterial disinfection is used, the protective cleaning solution can be used for the whole body, the personal protection function is more efficient, safe, mild and lasting, the skin infection risk can be well prevented and treated, the sterilization and disinfection effects are improved, the adverse reaction of a human body is reduced to the maximum extent, meanwhile, the decontamination capability is increased on the function of the traditional disinfectant, the protective cleaning solution integrates washing and protecting, and the number of bacteria and viruses on the skin can be greatly reduced at the initial stage of product use.
(II) technical scheme
The invention is realized by the following technical scheme: the invention provides a protective cleaning solution containing silver ion graphene oxide for antibiosis and disinfection, and a preparation method and steps thereof, wherein the protective cleaning solution comprises the following components in percentage by mass: 3.0-5.0% of cocamidopropyl betaine, 1.0-3.0% of glycerol, 1.0-10.0% of propylene glycol, 0.1-0.5% of carbomer, 0.1-0.5% of potassium hydroxide, 0.05-0.2% of hyaluronic acid and the balance of silver ion solution, graphene oxide dispersion solution and water, and the preparation method comprises the following steps:
(1) according to the weight portion, the cocamidopropyl betaine accounts for 3.0-5.0%, the glycerol accounts for 1.0-3.0%, and the dosage of the silver ion solution is 0.05-5.0 dosage of the total concentration of the protective cleaning solution; the graphene oxide dispersion solution is 0.1-3.0 dosage of the total concentration of the protective cleaning solution, and the purified water is added into a water pot until the concentration is 79.9% and heated to 80 ℃ for 40min to prepare a mixed solution A.
(2) Taking 0.1-0.5% of carbomer, 0.1-0.5% of potassium hydroxide, 1.0-10.0% of propylene glycol and purified water, fully adding the mixture to 20%, heating the mixture to 80 ℃ for 40min, and preparing a mixed solution B.
(3) Vacuumizing the emulsifying pot and keeping the vacuum degree of the emulsifying pot at 0.06Pa, and simultaneously starting a heating button of the emulsifying pot to heat the emulsifying pot.
(4) Slowly pumping the mixed solution A into an emulsifying pot under the vacuum condition, and keeping the temperature in the emulsifying pot at 80 ℃ at constant temperature.
(5) Slowly pumping the mixed solution B into an emulsifying pot with the stirring speed of 20/min; keeping the temperature in the emulsifying pot at 80 ℃ at constant temperature, starting a button of a homogenizer, and homogenizing and stirring for 8min at a stirring speed of 10 r/min; the rotation speed is increased, and the mixture is stirred for 15min at the stirring speed of 25 r/min.
(6) The cooling water is started and the speed of the cooling water is controlled, the cooling is carried out while stirring, and the temperature of the emulsifying pot is reduced to 60 ℃ within 45 min.
(7) Slowly adding 0.05-0.2% of hyaluronic acid into an emulsifying pot, and then starting a vacuum button to keep the vacuum degree in the emulsifying pot at 0.06 Pa; stirring to reduce the temperature in the emulsifying pot to 55 ℃; stirring for 15min to obtain mixed solution.
(8) Placing the mixed solution prepared in the step 7 in a sterilization container, cooling to 25 ℃, applying a preservative film, and sealing for 24 hours to obtain the preservative film.
Further, the dosage of the silver ion solution is 0.05-5.0ppm of the concentration of the protective cleaning solution.
Further, the concentration of the graphene oxide dispersion solution is 0.1-3.0ppm of the concentration of the protective cleaning solution.
(III) advantageous effects
Compared with the prior art, the invention has the following beneficial effects:
1. can be directly used by the skin of the whole body, has simple and effective method, provides corresponding comprehensive protection for the parts such as the limbs, the face, the hair and the like exposed outside, and overcomes the defects of the traditional antibacterial liquid.
2. The physical killing technology of silver ion graphene oxide antibacterial disinfection is used, the disinfectant can be used for the whole body, the decontamination capability is increased on the function of the traditional disinfectant, the cleaning and the protection are integrated, the number of bacteria and viruses on the skin can be greatly reduced at the initial stage of product use, and the personal protection function is more efficient, safe, mild and lasting.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the following embodiments further describe the present invention in detail. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
A protective cleaning solution containing silver ions and graphene oxide for antibiosis and disinfection comprises the following components in percentage by mass: 3.0-5.0% of cocamidopropyl betaine, 1.0-3.0% of glycerol, 1.0-10.0% of propylene glycol, 0.1-0.5% of carbomer, 0.1-0.5% of potassium hydroxide, 0.05-0.2% of hyaluronic acid and the balance of silver ion solution, graphene oxide dispersion solution and water, and the preparation method comprises the following steps: (1) according to the weight parts, the content of the cocamidopropyl betaine is 3.0-5.0%, the content of the glycerol is 1.0-3.0%, and the dosage of the silver ion solution is 0.05-5.0 dosage of the total concentration of the protective cleaning solution; adding purified water to 79.9% of the total concentration of the protective cleaning solution in 0.1-3.0 dose of the graphene oxide dispersion solution, adding the purified water into a water pot, heating to 80 ℃, and heating for 40min to obtain a mixed solution A; (2) taking 0.1-0.5% carbomer, 0.1-0.5% potassium hydroxide, 1.0-10.0% propylene glycol, and purified water, adding to 20%, heating to 80 deg.C, and standing for 40min to obtain mixed solution B; (3) vacuumizing the emulsifying pot, maintaining the vacuum degree of the emulsifying pot at 0.06Pa, and simultaneously starting a heating button of the emulsifying pot to heat the emulsifying pot; (4) slowly pumping the mixed solution A into an emulsifying pot under a vacuum condition, and keeping the temperature in the emulsifying pot at 80 ℃ at a constant temperature; (5) slowly pumping the mixed solution B into an emulsifying pot with the stirring speed of 20/min; keeping the temperature in the emulsifying pot at 80 ℃ at constant temperature, starting a button of a homogenizer, and homogenizing and stirring for 8min at a stirring speed of 10 r/min; increasing the rotating speed, and stirring for 15min at the stirring speed of 25 r/min; (6) starting cooling water, controlling the speed of the cooling water, cooling while stirring, and reducing the temperature of the emulsifying pot to 60 ℃ within 45 min; (7) slowly adding 0.05-0.2% of hyaluronic acid into an emulsifying pot, and then starting a vacuum button to keep the vacuum degree in the emulsifying pot at 0.06 Pa; stirring to reduce the temperature in the emulsifying pot to 55 ℃; stirring for 15min to obtain mixed solution; (8) and (4) placing the mixed solution prepared in the step (7) in a sterilization container, cooling to 25 ℃, applying a preservative film, and sealing for 24 hours to obtain the preservative film.
Wherein the dosage of the silver ion solution is 0.05-5.0ppm of the concentration of the protective cleaning solution; the concentration of the graphene oxide dispersion solution is 0.1-3.0ppm of the concentration of the protective cleaning solution.
Example 1
A protective cleaning solution containing silver ion graphene oxide for antibiosis and disinfection, a preparation method and an application. Comprises the following components in percentage by mass: 3.0% of cocamidopropyl betaine, 1.0% of glycerol, 1.0% of propylene glycol, 0.2% of carbomer, 0.1% of potassium hydroxide, 0.1% of hyaluronic acid and 0.1ppm of silver ion solution, wherein the dosage of the silver ion solution is 0.1ppm of the concentration of the protective cleaning solution; the concentration of the graphene oxide dispersion solution is 0.1ppm of the concentration of the protective cleaning solution, and the purified water is filled to 100%.
The preparation method of the silver ion graphene oxide antibacterial and disinfectant protective cleaning solution comprises the following steps:
(1) according to the weight parts, the content of the cocamidopropyl betaine is 3.0%, the content of the glycerol is 1.0%, and the dosage of the silver ion solution is 0.1ppm of the total concentration of the protective cleaning solution; the graphene oxide dispersion solution is 0.1ppm of the total concentration of the protective cleaning solution, and the purified water is added to a water kettle to be heated to 80 ℃ for 40min when the purified water is filled to 79.9%, so as to prepare a mixed solution A.
(2) Taking carbomer 0.2%, potassium hydroxide 0.1%, propylene glycol 1.0%, and purified water, adding to 20%, heating to 80 deg.C, and standing for 40min to obtain mixed solution B.
(3) Vacuumizing the emulsifying pot, maintaining the vacuum degree at 0.06Pa, and simultaneously starting a heating button of the emulsifying pot to heat the emulsifying pot.
(4) Slowly pumping the mixed solution A into an emulsifying pot under the vacuum condition, and keeping the temperature in the emulsifying pot at 80 ℃ at constant temperature.
(5) Slowly pumping the mixed solution B into an emulsifying pot with the stirring speed of 20/min; keeping the temperature in the emulsifying pot at 80 ℃ at constant temperature, starting a button of a homogenizer, and homogenizing and stirring for 8min at a stirring speed of 10 r/min; the rotation speed is increased, and the mixture is stirred for 15min at the stirring speed of 25 r/min.
(6) The cooling water is started, the speed of the cooling water is controlled, the cooling is carried out while stirring, and the temperature of the emulsifying pot is reduced to 60 ℃ within 45 min.
(7) Slowly adding 0.1% of hyaluronic acid into an emulsifying pot, and then starting a vacuum button to keep the vacuum degree in the emulsifying pot at 0.06 Pa; stirring to reduce the temperature in the emulsifying pot to 55 ℃; stirring for 15min to obtain mixed solution.
(8) And (4) placing the mixed solution prepared in the step (7) in a sterilization container, cooling to 25 ℃, applying a preservative film, and sealing for 24 hours to obtain the preservative film.
Example 2
A protective cleaning solution containing silver ion graphene oxide for antibiosis and disinfection, a preparation method and an application. Comprises the following components in percentage by mass: 2.0% of cocamidopropyl betaine, 2.0% of glycerol, 3.0% of propylene glycol, 0.2% of carbomer, 0.1% of potassium hydroxide, 0.2% of hyaluronic acid and 1.0ppm of silver ion solution, wherein the dosage of the silver ion solution is the concentration of the protective cleaning solution; the concentration of the graphene oxide dispersion solution is 1.1ppm of the concentration of the protective cleaning solution, and the purified water is filled to 100%.
The preparation method of the silver ion graphene oxide antibacterial and disinfectant protective cleaning solution comprises the following steps:
(1) according to the weight parts, the content of the cocamidopropyl betaine is 2.0 percent, the content of the glycerol is 2.0 percent, and the dosage of the silver ion solution is 1.0ppm of the total concentration of the protective cleaning solution; the graphene oxide dispersion solution is 1.0ppm of the total concentration of the protective cleaning solution, and the purified water is added to the water kettle to reach 79.8 percent and is heated to 80 ℃ for 40min, so as to prepare a mixed solution A.
(2) Taking 0.2% of carbomer, 0.1% of potassium hydroxide, 3.0% of propylene glycol and purified water, fully adding the mixture to 20%, heating the mixture to 80 ℃ for 40min, and obtaining a mixed solution B.
(3) Vacuumizing the emulsifying pot, maintaining the vacuum degree at 0.06Pa, and simultaneously starting a heating button of the emulsifying pot to heat the emulsifying pot.
(4) Slowly pumping the mixed solution A into an emulsifying pot under the vacuum condition, and keeping the temperature in the emulsifying pot at 80 ℃ at constant temperature.
(5) Slowly pumping the mixed solution B into an emulsifying pot with the stirring speed of 20/min; keeping the temperature in the emulsifying pot at 80 ℃ at constant temperature, starting a button of a homogenizer, and homogenizing and stirring for 8min at a stirring speed of 10 r/min; the rotation speed is increased, and the mixture is stirred for 15min at the stirring speed of 25 r/min.
(6) The cooling water is started, the speed of the cooling water is controlled, the cooling is carried out while stirring, and the temperature of the emulsifying pot is reduced to 60 ℃ within 45 min.
(7) Slowly adding 0.2% of hyaluronic acid into an emulsifying pot, and then starting a vacuum button to keep the vacuum degree in the emulsifying pot at 0.06 Pa; stirring to reduce the temperature in the emulsifying pot to 55 ℃; stirring for 15min to obtain mixed solution.
(8) And (4) placing the mixed solution prepared in the step (7) in a sterilization container, cooling to 25 ℃, applying a preservative film, and sealing for 24 hours to obtain the preservative film.
Example 3
A protective cleaning solution containing silver ion graphene oxide for antibiosis and disinfection, a preparation method and an application. Comprises the following components in percentage by mass: 5.0% of cocamidopropyl betaine, 3.0% of glycerol, 10.0% of propylene glycol, 0.2% of carbomer, 0.1% of potassium hydroxide, 0.05% of hyaluronic acid and 5.0ppm of silver ion solution, wherein the dosage of the silver ion solution is the concentration of the protective cleaning solution; the concentration of the graphene oxide dispersion solution is 3.0ppm of the concentration of the protective cleaning solution, and the purified water is filled to 100%.
The preparation method of the silver ion graphene oxide antibacterial and disinfectant protective cleaning solution comprises the following steps:
(1) according to the weight parts, the content of the cocamidopropyl betaine is 5.0%, the content of the glycerol is 3.0%, and the dosage of the silver ion solution is 5.0ppm of the total concentration of the protective cleaning solution; the graphene oxide dispersion solution is 3.0ppm of the total concentration of the protective cleaning solution, and the purified water is added to a water kettle to be heated to 80 ℃ for 40min when the purified water is filled to 79.95%, so as to prepare a mixed solution A.
(2) Taking 0.2% of carbomer, 0.1% of potassium hydroxide, 10.0% of propylene glycol and purified water, fully adding the mixture to 20%, heating the mixture to 80 ℃ for 40min, and obtaining a mixed solution B.
(3) Vacuumizing the emulsifying pot, maintaining the vacuum degree at 0.06Pa, and simultaneously starting a heating button of the emulsifying pot to heat the emulsifying pot.
(4) Slowly pumping the mixed solution A into an emulsifying pot under the vacuum condition, and keeping the temperature in the emulsifying pot at 80 ℃ at constant temperature.
(5) Slowly pumping the mixed solution B into an emulsifying pot with the stirring speed of 20/min; keeping the temperature in the emulsifying pot at 80 ℃ at constant temperature, starting a button of a homogenizer, and homogenizing and stirring for 8min at a stirring speed of 10 r/min; the rotation speed is increased, and the mixture is stirred for 15min at the stirring speed of 25 r/min.
(6) The cooling water is started, the speed of the cooling water is controlled, the cooling is carried out while stirring, and the temperature of the emulsifying pot is reduced to 60 ℃ within 45 min.
(7) Slowly adding 0.05% of hyaluronic acid into an emulsifying pot, and then starting a vacuum button to keep the vacuum degree in the emulsifying pot at 0.06 Pa; stirring to reduce the temperature in the emulsifying pot to 55 ℃; stirring for 15min to obtain mixed solution.
(8) And (4) placing the mixed solution prepared in the step (7) in a sterilization container, cooling to 25 ℃, applying a preservative film, and sealing for 24 hours to obtain the preservative film.
In the embodiment, the protective cleaning solution containing silver ion graphene oxide for antibacterial disinfection belongs to a protective technical formula combining physical sterilization, disinfection and washing and protection, is prepared from components such as silver ions, graphene oxide, glycerin, propylene glycol, cocoamidopropyl betaine and the like, can be used for the whole body, has a personal protection function more efficient, safe, mild and durable, can well prevent and treat skin infection risks, improves the sterilization and disinfection effect, reduces adverse reactions of a human body to the maximum extent, increases the decontamination capability on the function of a traditional disinfectant, integrates washing and protection, and can greatly reduce the number of bacteria and viruses on the skin at the initial stage of product use.
In the above components, the silver ions are silver in which silver atoms lose more than one electron, exist in an ionic state, and are generally positively charged, such as Ag +, Ag2+, Ag3+, and the like, the chemical structure of silver determines that silver has high catalytic ability, the reduction potential of silver in a high oxidation state is extremely high enough to generate atomic oxygen in the surrounding space, and atomic oxygen O2 has strong oxidizing property, so that sterilization can be achieved. Ag + can strongly attract thiol groups (-SH) on proteases in virus envelopes and bacterial cell membranes, and can be rapidly combined with the proteases to inactivate the proteases and kill bacteria and viruses, silver ions can kill bacteria without damaging beneficial bacteria and normal cells, because most pathogenic bacteria are unicellular microorganisms and rely on the proteases to maintain metabolism so as to propagate and influence normal cells, the proteases also contain an oxygen metabolism enzyme, when silver meets the oxygen metabolism enzyme, the activity of the oxygen metabolism enzyme can rob away one electron of the silver to change silver atoms into positively charged silver ions, and the silver ions can attract the specific combination of the thiol groups (-SH) with negative charges in the proteases, effectively puncture the cell walls and the cell membranes, further enable the bacterial cells to be incapable of breathing and breathing due to protein denaturation, Metabolizing and propagating until death, and achieving the effect of sterilization. The survival time of the pathogenic bacteria is only dozens of minutes, the pathogenic bacteria can die naturally under the condition of incapable propagation, and the silver ions can be reduced into silver atoms by the original electrons. The bactericidal function of the silver ions themselves is not lost.
Graphene is a two-dimensional carbon nanomaterial consisting of carbon atoms in a hexagonal honeycomb lattice with sp2 hybridized orbitals. The Graphene Oxide (GO) is the most researched antibacterial and antiviral graphene material at present, and the antibacterial and antiviral capacity of the graphene material is mainly based on the mixed synergistic effect of the following mechanisms:
1) physical cutting, also called Nano-Knives (Nano-knifes), sharp physical edges of graphene materials can effectively cut surfaces of bacterial viruses, destroy cell walls and membrane structures, cause leakage of substances in cells and metabolic disturbance, and finally cause death of the bacterial viruses, and the graphene materials are one of main antibacterial and antiviral mechanisms of the graphene materials.
2) The membrane surface component Extraction (intercalation and Extraction), the graphene material has large specific surface area and hydrophobicity, and can effectively adsorb phospholipid molecules bound on the surface of the bacterial virus in a contact or Insertion mode, so that the cell membrane structure of the bacterial virus is damaged to cause the bacterial virus to die.
3) Physical trapping (Wrapping), the graphene material can isolate bacteria from surrounding media in a Wrapping mode, so that the proliferation of the bacteria is blocked, and the antibacterial effect is achieved.
4) Oxidative Stress (ROS), during the contact process with bacteria, the surface defects and sharp edge structures of graphene can induce the bacteria to generate active oxygen components, so that the normal physiological metabolism of the bacteria is disturbed, and the bacteria die. In addition to the main antibacterial and antiviral mechanisms, charge conduction is also an important graphene antibacterial mechanism, and the mechanism conducts the charges on the surface of bacteria through graphene, destroys the physiological activities and functions of cell membranes, causes the metabolic disorder of the bacteria, and further promotes the death of the bacteria.
The propylene glycol has the characteristics of a fat-soluble solvent, is very strong in permeability and strong in dissolving power, can soften and destroy bacterial cell membranes and virus envelopes, promotes physical damage of silver ions and graphene oxide to bacteria and viruses, achieves an inhibiting effect, has very strong adhesion and hygroscopicity, prolongs the residence time of the silver ions and the graphene oxide on skin, can slow down the chemical loss of the silver ions and the graphene oxide in dry air, and keeps a lasting antibacterial and disinfection effect.
The above-described embodiments are merely illustrative of the preferred embodiments of the present invention and do not limit the spirit and scope of the present invention. Various modifications and improvements of the technical solutions of the present invention may be made by those skilled in the art without departing from the design concept of the present invention, and the technical contents of the present invention are all described in the claims.
Claims (3)
1. A protective cleaning solution containing silver ions and graphene oxide for antibiosis and disinfection comprises the following components in percentage by mass: 3.0-5.0% of cocamidopropyl betaine, 1.0-3.0% of glycerol, 1.0-10.0% of propylene glycol, 0.1-0.5% of carbomer, 0.1-0.5% of potassium hydroxide, 0.05-0.2% of hyaluronic acid and the balance of silver ion solution, graphene oxide dispersion solution and water, and the preparation method comprises the following steps:
(1) according to the weight portion, the cocamidopropyl betaine accounts for 3.0-5.0%, the glycerol accounts for 1.0-3.0%, and the dosage of the silver ion solution is 0.05-5.0 dosage of the total concentration of the protective cleaning solution; the graphene oxide dispersion solution is 0.1-3.0 dosage of the total concentration of the protective cleaning solution, and the purified water is added into a water pot until the concentration is 79.9% and heated to 80 ℃ for 40min to prepare a mixed solution A.
(2) Taking 0.1-0.5% of carbomer, 0.1-0.5% of potassium hydroxide, 1.0-10.0% of propylene glycol and purified water, fully adding the mixture to 20%, heating the mixture to 80 ℃ for 40min, and preparing a mixed solution B.
(3) Vacuumizing the emulsifying pot and keeping the vacuum degree of the emulsifying pot at 0.06Pa, and simultaneously starting a heating button of the emulsifying pot to heat the emulsifying pot.
(4) Slowly pumping the mixed solution A into an emulsifying pot under the vacuum condition, and keeping the temperature in the emulsifying pot at 80 ℃ at constant temperature.
(5) Slowly pumping the mixed solution B into an emulsifying pot with the stirring speed of 20/min; keeping the temperature in the emulsifying pot at 80 ℃ at constant temperature, starting a button of a homogenizer, and homogenizing and stirring for 8min at a stirring speed of 10 r/min; the rotation speed is increased, and the mixture is stirred for 15min at the stirring speed of 25 r/min.
(6) The cooling water is started and the speed of the cooling water is controlled, the cooling is carried out while stirring, and the temperature of the emulsifying pot is reduced to 60 ℃ within 45 min.
(7) Slowly adding 0.05-0.2% of hyaluronic acid into an emulsifying pot, and then starting a vacuum button to keep the vacuum degree in the emulsifying pot at 0.06 Pa; stirring to reduce the temperature in the emulsifying pot to 55 ℃; stirring for 15min to obtain mixed solution.
(8) Placing the mixed solution prepared in the step 7 in a sterilization container, cooling to 25 ℃, applying a preservative film, and sealing for 24 hours to obtain the preservative film.
2. The protective cleaning solution containing silver ion graphene oxide for antibacterial disinfection according to claim 1, is characterized in that: the dosage of the silver ion solution is 0.05-5.0ppm of the concentration of the protective cleaning solution.
3. The protective cleaning solution containing silver ion graphene oxide for antibacterial disinfection according to claim 1, is characterized in that: the concentration of the graphene oxide dispersion solution is 0.1-3.0ppm of the concentration of the protective cleaning solution.
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112156025A (en) * | 2020-09-30 | 2021-01-01 | 雅弗生物实验室有限公司(加拿大) | Silver ion induction biological micro-current membrane cloth and preparation method thereof |
| CN112716822A (en) * | 2021-02-03 | 2021-04-30 | 深圳市南门科技有限公司 | Disinfectant for resisting new coronavirus and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN112156025A (en) * | 2020-09-30 | 2021-01-01 | 雅弗生物实验室有限公司(加拿大) | Silver ion induction biological micro-current membrane cloth and preparation method thereof |
| CN112156025B (en) * | 2020-09-30 | 2023-03-31 | 雅弗生物实验室有限公司(加拿大) | Silver ion induction biological micro-current membrane cloth and preparation method thereof |
| WO2022126857A1 (en) * | 2020-12-17 | 2022-06-23 | 深圳先进技术研究院 | Use of two-dimensional nanomaterial in inhibition of coronavirus |
| CN112716822A (en) * | 2021-02-03 | 2021-04-30 | 深圳市南门科技有限公司 | Disinfectant for resisting new coronavirus and preparation method thereof |
| CN113767929A (en) * | 2021-10-13 | 2021-12-10 | 孙雪迎 | Durable graphene sterilizing and antibacterial liquid and preparation method thereof |
| CN114133650A (en) * | 2021-11-06 | 2022-03-04 | 深圳市真味生物科技有限公司 | Preparation and cleaning method of antibacterial suction nozzle for electronic atomization equipment |
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