CN111616825B - Fixing device for fixing rat testis for injection - Google Patents
Fixing device for fixing rat testis for injection Download PDFInfo
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- CN111616825B CN111616825B CN202010413896.1A CN202010413896A CN111616825B CN 111616825 B CN111616825 B CN 111616825B CN 202010413896 A CN202010413896 A CN 202010413896A CN 111616825 B CN111616825 B CN 111616825B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
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Abstract
The invention discloses a fixing device for fixing a rat testis for injection, which comprises a positioning tube, one end of the positioning tube is arranged in a conical shape, the other end of the positioning tube is provided with a bearing platform, a binding piece is arranged in the positioning tube, a sliding groove is arranged on the bearing platform, a butting seat is arranged in the sliding groove, a butting cam is rotationally arranged on the butting seat, the bearing table is provided with a hole seat, the hole seat is provided with an elastic binding arm which is arranged in a U shape in a swinging way, two free ends of the elastic binding arms are bent to form pins which are inserted in the hole seats, the elastic binding arm is tightly attached to the matching surface of the outer wall of the hole seat, a first positioning groove, a first convergence bulge, a second positioning groove, a second convergence bulge and a third positioning groove are sequentially formed on the matching surface, and the second positioning groove is deeper than the first positioning groove and the third positioning groove. The whole structure is simple, and the fixing of the rat testis can be realized, thereby facilitating the cell transplantation test.
Description
Technical Field
The invention relates to the technical field of medical experimental instruments, in particular to a fixing device for fixing a rat testis for injection.
Background
In cell transplantation experiments, it is usually necessary to fix the testis of a rat and then inject the cells to be transplanted into the testis of the rat through a micro-injection needle. However, in the operation process, because the testis of the rat is small in size, inconvenient in injection positioning and very sensitive, and is easy to shrink into the groin when being stimulated to influence the injection operation, two operators are required to perform the testis injection operation at present, one operator needs to restrain the rat, then fixes the testis of the rat by hand, and the other operator performs the injection operation, but the two operators are inconvenient to cooperate in the operation process, and due to injection, when the testis of the rat is restrained, the hind leg of the rat can struggle to influence the restraining action of the operator, so that the test efficiency is reduced.
Disclosure of Invention
Aiming at the defects of the prior art, the invention provides a fixing device for fixing a rat testis for injection, which has a simple overall structure and can realize the fixation of the rat testis so as to facilitate the cell transplantation test.
In order to achieve the above purpose, the invention provides a fixing device for fixing a rat testis for injection, which comprises a positioning tube, wherein one end of the positioning tube is arranged in a conical shape, the other end of the positioning tube is provided with a bearing table, a binding piece for binding the rat body is arranged in the positioning tube, a sliding groove is arranged on the bearing table along the length direction of the positioning tube, a contact seat is arranged in the sliding groove, a contact cam is rotatably arranged on the contact seat, a hole seat is arranged at one end of the bearing table far away from the positioning tube, a U-shaped elastic binding arm is arranged on the hole seat in a swinging manner, two free ends of the elastic binding arm are bent to form pins, the pins are inserted into the hole seat and arranged, and a first positioning groove, a first binding bulge, a second positioning groove, a second binding bulge and a third positioning groove are sequentially formed on a matching surface of the elastic binding arm, which is tightly attached to the outer wall of the hole seat, the second positioning groove is deeper than the first positioning groove and the third positioning groove.
The beneficial effect who so sets up is: the positioning tube and the bearing platform are arranged, the positioning tube can be placed on the test bed without overturning, the rat can be drilled into the positioning tube by utilizing the habit of drilling a hole in the rat, the front end of the positioning tube is arranged in a conical shape, the front claw of the rat can be effectively restrained, the movement of the front claw of the rat is limited, and an operator is prevented from being scratched, meanwhile, the positioning tube is also provided with a restraining piece which can restrain the rat body, the displacement of the rat caused by struggling of subsequent injection operation is avoided, the accuracy of subsequent test operation is ensured, after the restraining action is completed, the positioning tube is overturned to enable the abdomen of the rat to be upward, a contact seat and a contact cam are further arranged on the bearing platform, in the test operation, the position of the abdomen of the rat close to the groin is resisted through the contact cam, the contact cam has two functions, the starting end of one contact cam can abut against the groin tube, so as to seal the inguinal canal and the leading belt and avoid the testis from retracting into the inguinal canal, and secondly, when the testis of the rat retracts into the inguinal canal, the non-convex end of the abutting cam reciprocates at the position of the inguinal canal by swinging the abutting cam in a reciprocating way to relax the muscle of the rat and enable the testis to descend back into the scrotum so as to carry out subsequent operation, meanwhile, the elastic binding arm is also arranged, the two ends of the elastic binding arm are arranged in the hole seat to realize the swinging operation of the elastic binding arm, the further elastic binding arm has outward opening force due to the elasticity of the elastic binding arm, and the matching surface of the elastic binding arm and the hole seat is sequentially provided with a concave part and a convex part, the elastic binding arm is limited in the first positioning groove by the matching of the first positioning groove and the first retracting convex part, can be limited at the initial position, and is not easy to be accidentally deviated under the condition of no operation of an operator, when the operation enters the second positioning groove, the second positioning groove is deeper than the first positioning groove and the third positioning groove, wherein the depth refers to the width direction of the positioning pipe, the elastic constraint arm expands outwards due to the elasticity of the elastic constraint arm to form an open V-shaped mode, so that the elastic constraint arm can not clamp a rat testis when passing through the testis position, the rat testis is prevented from being stimulated to retract, the elastic constraint arm further swings to enter the third positioning groove, the elastic constraint arm is constrained through the matching of the third positioning groove and the second constraint bulge, the opening in the middle of the elastic constraint arm is smaller than the width of two testes of the rat, and the elastic constraint arm is folded in the third positioning groove to play a role of positioning and pressing, so that the testis is positioned, the subsequent injection operation is convenient, the structure is simple, and the positioning of the whole rat and the testis position can be realized by one operator, effectively avoid the rat testicle to receive the amazing and retract into the groin, the simple operation, follow-up injection is more smooth and easy, improves test efficiency.
As a further arrangement of the invention, a plurality of clamping grooves are arranged at intervals on two sides of the sliding groove, clamping blocks are arranged on the side wall of the contact base, and the clamping blocks are clamped with the clamping grooves to form the fixation of the contact base on the sliding groove.
The beneficial effect who so sets up is: set up like this, can be through removing the butt seat, thereby adjust the conflict position of conflict cam, the rat of the different size of adaptation, make the conflict cam can conflict in suitable position, the realization is sealed the conflict of rat groin pipe, prevent that the rat testicle from retracting the groin, the use effect is improved, further joint location through joint piece and joint groove, realize the fixing to the butt seat position, the skew appears in avoiding the use, guarantee the stability of position, thereby guarantee the conflict effect, simultaneously this kind of joint structure simple structure, do benefit to the realization, the operation is convenient, can realize quick installation location, the result of use and the availability factor of overall structure are improved.
As a further arrangement of the invention, a spacing ring groove is formed in the middle of the interference cam, and a plurality of interference bulges are arranged on the interference cam at intervals.
The beneficial effect who so sets up is: set up like this, set up the interval annular, reduce the extrusion to the rat abdominal cavity, reduce the injury to the rat, set up simultaneously and contradict protrudingly, after the testicle retraction groin of target rat, can pass through reciprocating rotation cam, be the reciprocal conflict rat groin position in non-bellied one side of cam, can massage through the conflict arch and relax the rat, order about the testicle and move down to make things convenient for follow-up location injection operation, this kind of simple structure does benefit to the realization, improves overall structure's result of use.
The binding piece is further arranged to be a binding belt, a binding opening is formed in the outer wall of the positioning pipe along the axial direction of the positioning pipe, one end of the binding belt is fixedly connected into the positioning pipe and is arranged close to the binding opening, the other end of the binding belt penetrates out of the binding opening after surrounding along the inner peripheral wall of the positioning pipe, an elastic snap spring used for pressing the binding belt on the inner wall of the positioning pipe is further wrapped in the binding belt, an adhesive buckle is further arranged at one end of the binding belt exposed out of the positioning pipe, and adhesive cloth is arranged on the outer wall of the positioning pipe.
The beneficial effect who so sets up is: the binding piece is arranged in such a way, after a rat is drilled into the positioning pipe, one end of the binding belt exposed out of the positioning pipe is pulled, so that the binding belt is tightened, the body position of the rat is fixed, the movement range of the body in the rat injection operation is reduced, the injection efficiency and the injection effect are improved, further, after the binding belt is tightened, the binding belt can be attached to sticky cloth through an adhesive buckle, so that both hands are liberated, an elastic snap spring used for pressing the binding belt on the inner wall of the positioning pipe is arranged in the binding belt, the phenomenon that the mouse touches the binding belt when being drilled is avoided, the position of the binding belt is influenced, the using effect of the binding belt is ensured, meanwhile, the structure is simple, the implementation is facilitated, and a good binding effect is achieved.
As a further arrangement of the invention, a limiting flange is arranged in the middle of the elastic constraint arm.
The beneficial effect who so sets up is: set up like this when through the second constant head tank, the limit flange position opens to make rat testicle position can pass through limit flange, when elasticity constraint arm reachd the third constant head tank position, because the second constant head tank is dark in the setting of third constant head tank, make limit flange draw in, thereby push down rat testicle both sides through elasticity constraint arm, seal and draw the area, avoid the testicle retraction, can fix a position the testicle simultaneously, make things convenient for the injection operation.
As a further arrangement of the invention, the outer wall of the elastic constraint arm is sleeved with a soft sleeve.
The beneficial effect who so sets up is: set up the soft cover and slow down the stimulation to the rat, the fish tail rat can be avoided to the soft cover simultaneously, reduces struggling of rat.
Drawings
FIG. 1 is a schematic structural diagram of an embodiment of the present invention;
FIG. 2 is an enlarged view of a portion A of FIG. 1 according to an embodiment of the present invention;
fig. 3 is a schematic front view of the structure according to the embodiment of the present invention.
Detailed Description
The embodiment of the fixing device for fixing rat testis for injection of the invention is shown in figure 1, figure 2 and figure 3: comprises a positioning tube 1, one end of the positioning tube 1 is arranged in a conical shape, the other end is provided with a bearing table 2, a binding piece for binding a rat body is arranged in the positioning tube 1, a sliding groove 21 is arranged on the bearing table 2 along the length direction of the positioning tube 1, a contact seat 3 is arranged in the sliding groove 21, a contact cam 4 is rotatably arranged on the contact seat 3, a hole seat 6 is arranged at one end of the bearing table 2 far away from the positioning tube 1, a U-shaped elastic binding arm 5 is arranged on the hole seat 6 in a swinging manner, two free ends of the elastic binding arm 5 are bent to form pins which are inserted in the hole seat 6, a first positioning groove 61, a first binding bulge 64, a second positioning groove 62, a second binding bulge 65 and a third positioning groove 63 are sequentially formed on the matching surface of the elastic binding arm 5 tightly attached to the outer wall of the hole seat 6, the second positioning groove 62 is deeper than the first positioning groove 61 and the third positioning groove 63. The beneficial effect who so sets up is: the positioning tube 1 and the bearing platform 2 are arranged, the positioning tube 1 can be placed on a test bed without overturning by matching the bearing platform 2 with the positioning tube 1, a rat can be driven into the positioning tube 1 by utilizing the drilling habit of the rat, the front end of the positioning tube 1 is arranged in a conical shape, the front claw of the rat can be effectively bound, the movement of the front claw of the rat is limited, the scratching of an operator is avoided, meanwhile, a binding piece is also arranged in the positioning tube 1, the rat can be bound, the displacement of the rat caused by struggling of subsequent injection operation is avoided, the accuracy of the subsequent test operation is ensured, after the binding action is completed, the positioning tube 1 is overturned to enable the abdomen of the rat to face upwards, a contact seat 3 and a contact cam 4 are further arranged on the bearing platform 2, in the test operation, the position of the abdomen of the rat close to a groin is resisted by the contact cam 4, and the contact cam 4 has two functions, the convex end of one of the abutting cam 4 can abut against the inguinal canal so as to seal the inguinal canal and the leading belt and prevent the testis from retracting into the inguinal canal, and the non-convex end of the abutting cam 4 reciprocates at the position of the inguinal canal by swinging the abutting cam 4 back and forth under the condition that the rat testis retracts into the inguinal canal so as to relax the muscle of the rat and enable the testis to descend back into the scrotum so as to carry out subsequent operation, meanwhile, the elastic binding arm 5 is also arranged, two ends of the elastic binding arm 5 are arranged in the hole seat 6 so as to realize the swinging operation of the elastic binding arm 5, the further elastic binding arm 5 has outward opening force due to the elasticity of the elastic binding arm 5, the matching surface of the elastic binding arm 5 and the hole seat 6 is sequentially provided with the recess and the protrusion, the elastic binding arm 5 is limited in the first positioning groove 61 through the matching of the first positioning groove 61 and the first collecting protrusion 64, can be limited at the initial position, is not easy to be accidentally deviated without the operation of an operator, when the operation enters the second positioning groove 62, because the second positioning groove 62 is deeper than the first positioning groove 61 and the third positioning groove 63, the depth refers to the width direction of the positioning tube 1, the elastic constraint arm 5 expands and forms an open V-shaped pattern due to the self elasticity, so that the elastic constraint arm 5 can not clamp a rat testis when passing through the testis position, the rat testis is prevented from being stimulated and retracted, the elastic constraint arm 5 is further swung to enter the third positioning groove 63, the elastic constraint arm 5 is constrained through the cooperation of the third positioning groove 63 and the second constraint bulge, the opening at the middle position of the elastic constraint arm 5 is smaller than the width of the two rat testis, and the elasticity of the elastic constraint arm 5 plays a role of positioning and abutting pressure due to the folding of the third positioning groove 63, thereby realize the location to the testicle, make things convenient for follow-up injection operation, this kind of simple structure can realize the location to the whole and testicle position of rat through an operator, effectively avoids the rat testicle to receive the stimulation and retract into the groin, the simple operation, follow-up injection is more smooth and easy, improves test efficiency.
As a further arrangement of the present invention, a plurality of clamping grooves 22 are arranged at intervals on two sides of the sliding groove 21, a clamping block 31 is arranged on the side wall of the contact base 3, and the clamping block 31 and the clamping groove 22 are clamped to form a fixation of the contact base 3 on the sliding groove 21. The beneficial effect who so sets up is: set up like this, can be through removing the conflict seat 3, thereby the conflict position of adjustment conflict cam 4, the rat of the different size of adaptation, make conflict cam 4 can conflict in suitable position, the realization is sealed the conflict of rat groin pipe, prevent that the rat testicle from retracting the groin, the result of use is improved, further joint location through joint piece 31 and joint groove 22, realize the fixed to the 3 positions of conflict seat, the skew appears in avoiding the use, guarantee the stability of position, thereby guarantee the effect of contradicting, this kind of joint structure simple structure simultaneously, do benefit to the realization, the operation is convenient, can realize quick installation location, the result of use and the availability factor of improvement overall structure.
As a further arrangement of the present invention, a spacing ring groove 41 is formed in the middle of the interference cam 4, and a plurality of interference protrusions 42 are further formed on the interference cam 4 at intervals. The beneficial effect who so sets up is: set up like this, set up interval annular 41, reduce the extrusion to the rat abdominal cavity, reduce the injury to the rat, set up conflict arch 42 simultaneously, after the testicle retraction groin of target rat, can pass through reciprocating rotation cam, be the reciprocal conflict rat groin position in non-bellied one side of cam, can massage through conflict arch 42 and relax the rat, it moves down to order about the testicle, thereby make things convenient for follow-up location injection operation, this kind of simple structure does benefit to the realization, improve overall structure's result of use.
As a further arrangement of the invention, the binding piece is arranged as a binding belt 11, a binding opening is arranged on the outer wall of the positioning tube 1 along the axial direction of the positioning tube 1, one end of the binding belt 11 is fixedly connected in the positioning tube 1 and is arranged close to the binding opening, the other end of the binding belt 11 is arranged to penetrate out of the binding opening after surrounding along the inner circumferential wall of the positioning tube 1, an elastic snap spring for pressing the binding belt 11 on the inner wall of the positioning tube 1 is further wrapped in the binding belt 11, an adhesive buckle is further arranged at one end of the binding belt 11 exposed out of the positioning tube 1, and adhesive cloth 12 is arranged on the outer wall of the positioning tube 1. The beneficial effect who so sets up is: the binding piece is arranged in such a way, after a rat is drilled into the positioning pipe 1, one end of the binding belt 11 exposed out of the positioning pipe 1 is pulled, so that the binding belt 11 is tightened, the fixing of the body position of the rat is achieved, the motion range of the body in the rat injection operation is reduced, the injection efficiency and the injection effect are improved, further, after the binding belt 11 is tightened, the binding belt can be attached to the sticky cloth 12 through the sticky buckles, so that both hands are liberated, the elastic clamp spring used for pressing the binding belt 11 onto the inner wall of the positioning pipe 1 is arranged in the binding belt 11, the phenomenon that the rat touches the binding belt 11 when the rat is drilled is avoided, the position of the binding belt 11 is affected, the using effect of the binding belt 11 is guaranteed, meanwhile, the structure is simple, the implementation is facilitated, and a good binding effect is achieved.
As a further arrangement of the invention, a limit flange is arranged in the middle of the elastic constraint arm 5. The beneficial effect who so sets up is: set up like this when second constant head tank 62, the limit flange position opens to make the rat testicle position can pass through limit flange, when elastic constraint arm 5 reachd third constant head tank 63 position, because second constant head tank 62 is dark in the setting of third constant head tank 63, make limit flange draw in, thereby support through elastic constraint arm 5 and press rat testicle both sides, seal the area of drawing, avoid the testicle retraction, can fix a position the testicle simultaneously, make things convenient for the injection operation.
As a further arrangement of the invention, the outer wall of the elastic constraint arm 5 is sleeved with a soft sleeve. The beneficial effect who so sets up is: set up the soft cover and slow down the stimulation to the rat, the fish tail rat can be avoided to the soft cover simultaneously, reduces struggling of rat.
The above example is only one of the preferred embodiments of the present invention, and general changes and substitutions by those skilled in the art within the technical scope of the present invention are included in the protection scope of the present invention.
Claims (6)
1. A fixing device for fixing a rat testis for injection is characterized in that: comprises a positioning tube, one end of the positioning tube is arranged in a conical shape, the other end of the positioning tube is provided with a bearing platform, a binding piece for binding the body of a rat is arranged in the positioning tube, a sliding groove is arranged on the bearing table along the length direction of the positioning pipe, a contact seat is arranged in the sliding groove, a conflict cam is rotationally arranged on the conflict seat, a hole seat is arranged at one end of the plummer far away from the positioning pipe, the hole seat is provided with an elastic binding arm in a U shape in a swinging way, two free ends of the elastic binding arm are bent to form a pin, the plug pins are inserted into the hole seats and arranged, the elastic binding arms are sequentially provided with a first positioning groove, a first collecting bulge, a second positioning groove, a second collecting bulge and a third positioning groove on the matching surface clinging to the outer wall of the hole seats, and the second positioning groove is deeper than the first positioning groove and the third positioning groove.
2. A holding device for holding a rat testis for injection according to claim 1, wherein: the sliding groove is provided with a plurality of clamping grooves at intervals on two sides, the abutting seat side wall is provided with a clamping block, and the clamping block and the clamping grooves are clamped to form fixation of the abutting seat on the sliding groove.
3. A fixation device for fixing a rat testis for injection according to claim 1 or 2, characterized in that: the middle of the conflict cam is provided with a spacing ring groove, and the conflict cam is also provided with a plurality of conflict bulges at intervals.
4. A holding device for holding a rat testis for injection according to claim 1, wherein: the binding piece is arranged to be a binding belt, a binding opening is formed in the outer wall of the positioning pipe in the axial direction of the positioning pipe, one end of the binding belt is fixedly connected in the positioning pipe and is close to the binding opening, the other end of the binding belt penetrates out of the binding opening after being surrounded by the inner peripheral wall of the positioning pipe, an elastic snap spring used for pressing the binding belt on the inner wall of the positioning pipe is further wrapped in the binding belt, a sticking buckle is further arranged at one end of the binding belt exposed out of the positioning pipe, and sticky cloth is arranged on the outer wall of the positioning pipe.
5. A holding device for holding a rat testis for injection according to claim 1, wherein: and a limiting flange is arranged in the middle of the elastic constraint arm.
6. A holding device for holding a rat testis for injection according to claim 1, wherein: the outer wall of the elastic binding arm is sleeved with a soft sleeve.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010413896.1A CN111616825B (en) | 2020-05-15 | 2020-05-15 | Fixing device for fixing rat testis for injection |
| KR1020210061068A KR102504889B1 (en) | 2020-05-15 | 2021-05-12 | Fixing device for fixing rat testis for injection |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010413896.1A CN111616825B (en) | 2020-05-15 | 2020-05-15 | Fixing device for fixing rat testis for injection |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN111616825A CN111616825A (en) | 2020-09-04 |
| CN111616825B true CN111616825B (en) | 2021-07-20 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010413896.1A Active CN111616825B (en) | 2020-05-15 | 2020-05-15 | Fixing device for fixing rat testis for injection |
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| Country | Link |
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| KR (1) | KR102504889B1 (en) |
| CN (1) | CN111616825B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114099048B (en) * | 2021-10-29 | 2022-10-25 | 西安交通大学 | A tail vein injection device for male mouse |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH08131465A (en) * | 1994-11-04 | 1996-05-28 | Dai Ichi Pure Chem Co Ltd | Experimental animal fixing device |
| US7213538B2 (en) * | 2004-01-14 | 2007-05-08 | The Board Of Regents Of The University Of Texas System | Animal restraining apparatus for physiological and pharmacological studies |
| US7402137B2 (en) * | 2004-05-04 | 2008-07-22 | Buxco Electronics, Inc. | Adjustable table plethysmograph |
| CN201316328Y (en) * | 2008-12-09 | 2009-09-30 | 北京大学第三医院 | Animal operation table surface |
| KR101302884B1 (en) * | 2011-10-07 | 2013-09-05 | 한국화학연구원 | Mouse Holder |
| CN203677297U (en) * | 2013-11-18 | 2014-07-02 | 吴翊馨 | Fixing device for anesthetic injection of rat |
| KR101967867B1 (en) * | 2017-09-29 | 2019-04-11 | 한국생명공학연구원 | Apparatus for acquiring bio-signal of laboratory animal and system for measuring bio-signal having the same |
| CN107898527B (en) * | 2017-11-22 | 2019-12-03 | 福州太古农业科技有限公司 | One kind being used for hog auxiliary device |
| CN109966007A (en) * | 2019-03-27 | 2019-07-05 | 华中科技大学 | A kind of mouse testis heat shock experiment container |
| KR102038991B1 (en) | 2019-07-30 | 2019-10-31 | 박성걸 | A Restrainer for breeding or injection the tail vein of small animals |
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2020
- 2020-05-15 CN CN202010413896.1A patent/CN111616825B/en active Active
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2021
- 2021-05-12 KR KR1020210061068A patent/KR102504889B1/en active IP Right Grant
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| Publication number | Publication date |
|---|---|
| CN111616825A (en) | 2020-09-04 |
| KR20210141378A (en) | 2021-11-23 |
| KR102504889B1 (en) | 2023-02-28 |
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