CN111603471B - 一种邻二氮杂环化合物在制备抑制tlr4受体的药物中的用途 - Google Patents
一种邻二氮杂环化合物在制备抑制tlr4受体的药物中的用途 Download PDFInfo
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- CN111603471B CN111603471B CN202010591073.8A CN202010591073A CN111603471B CN 111603471 B CN111603471 B CN 111603471B CN 202010591073 A CN202010591073 A CN 202010591073A CN 111603471 B CN111603471 B CN 111603471B
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
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SG11201704628VA (en) * | 2015-02-05 | 2017-07-28 | Merck Patent Gmbh | Macrocyclic compounds as irak1/4 inhibitors and uses thereof |
WO2016127024A1 (en) * | 2015-02-06 | 2016-08-11 | Merck Patent Gmbh | Pyridazinone macrocycles as irak inhibitors and uses thereof |
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CN105601617B (zh) * | 2016-03-24 | 2019-02-22 | 山东省科学院生物研究所 | 一种邻二氮杂环化合物及其制备方法与应用 |
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